DATE_ADDED_TO_CATALOG	PUBMEDID	FIRST_AUTHOR	DATE	JOURNAL	LINK	STUDY	DISEASE_TRAIT	INITIAL_SAMPLE_SIZE	REPLICATION_SAMPLE_SIZE	REGION	CHR_ID	CHR_POS	REPORTED_GENE(S)	MAPPED_GENE	UPSTREAM_GENE_ID	DOWNSTREAM_GENE_ID	SNP_GENE_IDS	UPSTREAM_GENE_DISTANCE	DOWNSTREAM_GENE_DISTANCE	STRONGEST_SNP-RISK_ALLELE	SNPS	MERGED	SNP_ID_CURRENT	CONTEXT	INTERGENIC	RISK_ALLELE_FREQUENCY	P-VALUE	PVALUE_MLOG	P-VALUE_(TEXT)	OR_or_BETA	95%_CI_(TEXT)	PLATFORM_[SNPS_PASSING_QC]	CNV	MAPPED_TRAIT	MAPPED_TRAIT_URI	STUDY_ACCESSION	GENOTYPING_TECHNOLOGY	risk_allele_freq	oddsratio	beta
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	5q11.2	5	56510924	NR	RPL26P19 - C5orf67	ENSG00000226221	ENSG00000225940	NA	5852	643	rs459193-A	rs459193	0	459193	intergenic_variant	TRUE	0.263207257894075	6e-10	9.221848749616356	NA	0.022980455	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.263207257894075	NA	0.022980455
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	5q35.2	5	173921153	NR	CPEB4	NA	NA	ENSG00000113742	NA	NA	rs10516107-A	rs10516107	0	10516107	intron_variant	FALSE	0.326573038451688	3e-12	11.522878745280337	NA	0.024094902	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.326573038451688	NA	0.024094902
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	5q35.3	5	177100576	NR	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-T	rs6556301	0	6556301	intergenic_variant	TRUE	0.355742327647949	7e-8	7.154901959985743	NA	0.020001272	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.355742327647949	NA	0.020001272
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	6p25.1	6	6738519	NR	LY86 - BTF3P7	ENSG00000112799	ENSG00000219986	NA	83536	56396	rs1294410-T	rs1294410	0	1294410	intron_variant	TRUE	0.366834831644638	1e-16	16	NA	0.027864806	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.366834831644638	NA	0.027864806
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	6p21.32	6	32386651	NR	TSBP1-AS1	NA	NA	ENSG00000225914	NA	NA	rs4424066-A	rs4424066	0	4424066	intron_variant	FALSE	0.578029598622173	7e-14	13.154901959985743	NA	0.024764335	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.578029598622173	NA	0.024764335
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	6q22.33	6	127131790	NR	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs2745353-T	rs2745353	0	2745353	intron_variant	FALSE	0.513045531553055	7e-41	40.15490195998574	NA	0.043643847	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.513045531553055	NA	0.043643847
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	7p15.2	7	25817905	NR	NA	NA	NA	NA	NA	NA	rs4141278-T	rs4141278	0	4141278	intergenic_variant	TRUE	0.801724671969546	4e-16	15.397940008672037	NA	0.033633854	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.801724671969546	NA	0.033633854
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	7p15.2	7	27184152	NR	HOXA11	NA	NA	ENSG00000005073	NA	NA	rs7801581-T	rs7801581	0	7801581	intron_variant	FALSE	0.245530226279377	7e-12	11.154901959985743	NA	0.028230367	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.245530226279377	NA	0.028230367
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	8p21.2	8	23745811	NR	NKX2-6 - STC1	ENSG00000180053	ENSG00000159167	NA	39055	96118	rs7830933-A	rs7830933	0	7830933	intron_variant	TRUE	0.766227574005384	8e-7	6.096910013008056	NA	0.01889321	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.766227574005384	NA	0.01889321
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	8q13.3	8	71580003	NR	EYA1	NA	NA	ENSG00000104313	NA	NA	rs12549058-T	rs12549058	0	12549058	intron_variant	FALSE	0.920749920492886	7e-9	8.154901959985743	NA	0.037428677	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.920749920492886	NA	0.037428677
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	9q31.1	9	104964637	NR	ABCA1 - CT70	ENSG00000165029	ENSG00000230013	NA	36482	5956	rs10991433-T	rs10991433	0	10991433	intergenic_variant	TRUE	0.887123614680935	7e-12	11.154901959985743	NA	0.036508307	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.887123614680935	NA	0.036508307
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	12p11.23	12	26318431	NR	SSPN - ITPR2	ENSG00000123096	ENSG00000123104	NA	19141	16921	rs10842707-T	rs10842707	0	10842707	intron_variant	TRUE	0.232379900368638	1e-19	19	NA	0.034759838	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.232379900368638	NA	0.034759838
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	12q13.13	12	53955989	NR	HOXC12	NA	NA	ENSG00000123407	NA	NA	rs10783615-A	rs10783615	0	10783615	intron_variant	FALSE	0.855651556311748	3e-14	13.522878745280337	NA	0.036315188	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.855651556311748	NA	0.036315188
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	12q24.31	12	123924955	NR	CCDC92, DNAH10	NA	NA	ENSG00000119242, ENSG00000197653	NA	NA	rs7133378-A	rs7133378	0	7133378	intron_variant	FALSE	0.31614887027496	1e-14	14	NA	0.027374689	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.31614887027496	NA	0.027374689
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	15q13.3	15	31416060	NR	KLF13, KLF13	NA	NA	ENSG00000275746, ENSG00000169926	NA	NA	rs8042543-T	rs8042543	0	8042543	intron_variant	FALSE	0.212439614225287	2e-9	8.698970004336019	NA	0.025153223	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.212439614225287	NA	0.025153223
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	15q21.3	15	56236608	NR	RFX7	NA	NA	ENSG00000181827	NA	NA	rs12595496-A	rs12595496	0	12595496	intron_variant	FALSE	0.875928267939582	4e-9	8.397940008672037	NA	0.029148584	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.875928267939582	NA	0.029148584
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	15q22.31	15	66740813	NR	SMAD6	NA	NA	ENSG00000137834	NA	NA	rs1440372-T	rs1440372	0	1440372	non_coding_transcript_exon_variant	FALSE	0.294481057263378	3e-10	9.522878745280337	NA	0.023097303	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.294481057263378	NA	0.023097303
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	17p11.2	17	17516885	NR	PEMT	NA	NA	ENSG00000133027	NA	NA	rs4646404-A	rs4646404	0	4646404	intron_variant	FALSE	0.34295575089661	5e-12	11.301029995663981	NA	0.026232956	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.34295575089661	NA	0.026232956
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	19p13.11	19	18278325	NR	IQCN - JUND	ENSG00000130518	ENSG00000130522	NA	3816	1369	rs12608504-A	rs12608504	0	12608504	regulatory_region_variant	TRUE	0.357006954395047	1e-8	8	NA	0.019687975	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.357006954395047	NA	0.019687975
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	19q13.11	19	33395448	NR	PEPD	NA	NA	ENSG00000124299	NA	NA	rs7258031-T	rs7258031	0	7258031	intron_variant	FALSE	0.339355889807184	3e-14	13.522878745280337	NA	0.026753515	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.339355889807184	NA	0.026753515
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	20p12.3	20	6642727	NR	NA - LINC01713	NA	ENSG00000228482	NA	NA	88353	rs979012-T	rs979012	0	979012	intergenic_variant	TRUE	0.344993542700339	7e-15	14.154901959985743	NA	0.02709985	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.344993542700339	NA	0.02709985
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	20q11.22	20	35385145	NR	UQCC1	NA	NA	ENSG00000101019	NA	NA	rs4911180-A	rs4911180	0	4911180	intron_variant	FALSE	0.603048781484029	3e-9	8.522878745280337	NA	0.019708263	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.603048781484029	NA	0.019708263
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	20q13.12	20	46874575	NR	RN7SKP33 - EYA2	ENSG00000222874	ENSG00000064655	NA	14903	20049	rs6012059-A	rs6012059	0	6012059	intergenic_variant	TRUE	0.387352850701881	5e-12	11.301029995663981	NA	0.027685227	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.387352850701881	NA	0.027685227
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	22q12.1	22	29054935	NR	ZNRF3	NA	NA	ENSG00000183579	NA	NA	rs2179129-A	rs2179129	0	2179129	3_prime_UTR_variant	FALSE	0.587757226661405	1e-15	15	NA	0.026648788	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.587757226661405	NA	0.026648788
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI (age <50)	up to 43,776 European ancestry men, up to 50,526 European ancestry women	NA	4q22.1	4	88791970	FAM13A, HERC6, HERC5, PIGY, PYURF, HERC3, NAP1L5, FAM13A-AS1, TIGD2, GPRIN3	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs9991328-T	rs9991328	0	9991328	intron_variant	FALSE	0.49	2e-6	5.698970004336019	(women)	0.034	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005957	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.49	NA	0.034
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	4q31.21	4	144616698	HHIP-AS1, GYPA, ANAPC10, ABCE1	KRT18P51 - HHIP-AS1	ENSG00000250504	ENSG00000248890	NA	43715	26224	rs11947381-T	rs11947381	0	11947381	intron_variant	TRUE	0.463079500710578	2e-8	7.698970004336019	NA	0.01867371	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.463079500710578	NA	0.01867371
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	6q24.1	6	139514552	ABRACL, HECA, TXLNB, LOC645434, LOC100132735	LINC01625 - ATP5PBP6	ENSG00000238099	ENSG00000219806	NA	39894	99886	rs668459-T	rs668459	0	668459	intron_variant	TRUE	0.574702916942344	6e-9	8.221848749616356	NA	0.019618856	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.574702916942344	NA	0.019618856
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	7p21.1	7	20380528	MACC1, MACC1-AS1, ABCB5, SP8, RPL23P8	ITGB8	NA	NA	ENSG00000105855	NA	NA	rs4721902-T	rs4721902	0	4721902	non_coding_transcript_exon_variant	FALSE	0.607172346625404	3e-8	7.522878745280337	NA	0.021385951	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.607172346625404	NA	0.021385951
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	7q31.1	7	107973558	COG5, GPR22, DUS4L, BCAP29, SLC26A4-AS1, SLC26A4, CBLL1, SLC26A3, DLD, LAMB4, NRCAM, PNPLA8	LAMB1	NA	NA	ENSG00000091136	NA	NA	rs4727695-A	rs4727695	0	4727695	intron_variant	FALSE	0.908759033200764	2e-8	7.698970004336019	NA	0.03303066	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.908759033200764	NA	0.03303066
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	7q31.2	7	117249664	MET, CAPZA2, ST7-AS1, ST7, ST7-OT4, ST7-AS2, ST7-OT3, ASZ1, CFTR, CTTNBP2	ST7 - MTND4P6	ENSG00000004866	ENSG00000224042	NA	19488	14253	rs38902-A	rs38902	0	38902	intergenic_variant	TRUE	0.515765264231727	5e-9	8.301029995663981	NA	0.021886844	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.515765264231727	NA	0.021886844
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	10p11.22	10	31701695	ZEB1-AS1, ZEB1, KIF5B	MACORIS	NA	NA	ENSG00000237797	NA	NA	rs7081678-A	rs7081678	0	7081678	intron_variant	FALSE	0.079330886319744	2e-8	7.698970004336019	NA	0.041659556	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.079330886319744	NA	0.041659556
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	11q12.3	11	62567436	SCGB2A1, SCGB1D2, SCGB2A2, SCGB1D4, ASRGL1, SCGB1A1, AHNAK, MIR3654, TUT1, MTA2, EML3, ROM1, B3GAT3, GANAB, INTS5, C11orf48, METTL12, SNORA57, C11orf83, UBXN1, LRRN4CL, BSCL2, HNRNPUL2-BSCL2, GNG3, TTC9C, ZBTB3, POLR2G, TAF6L, TMEM179B, TMEM223, NXF1, STX5, WDR74, SNHG1, SNORD22, SNORD31, INCENP, SCGB1D1	EEF1G	NA	NA	ENSG00000254772	NA	NA	rs1061093-C	rs1061093	0	1061093	synonymous_variant	FALSE	0.347173947735835	1e-8	8	NA	0.023226092	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.347173947735835	NA	0.023226092
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	15q24.1	15	73192819	BBS4, ADPGK, ADPGK-AS1, HCN4, C15orf60, NPTN	NEO1	NA	NA	ENSG00000067141	NA	NA	rs11072405-A	rs11072405	0	11072405	intron_variant	FALSE	0.564379482293836	1e-8	8	NA	0.021156829	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.564379482293836	NA	0.021156829
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	1p12	1	119031964	NR	WARS2	NA	NA	ENSG00000116874	NA	NA	rs2645294-T	rs2645294	0	2645294	3_prime_UTR_variant	FALSE	0.577416449101785	2e-25	24.69897000433602	NA	0.03445078	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.577416449101785	NA	0.03445078
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	1q21.3	1	155018913	NR	DCST2	NA	NA	ENSG00000163354	NA	NA	rs905938-T	rs905938	0	905938	intron_variant	FALSE	0.734309758354771	4e-10	9.397940008672037	NA	0.024901243	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.734309758354771	NA	0.024901243
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	1q24.2	1	170403362	NR	HAUS4P1 - GORAB-AS1	ENSG00000226967	ENSG00000231407	NA	32995	57091	rs10919388-A	rs10919388	0	10919388	intergenic_variant	TRUE	0.277856953814921	7e-11	10.154901959985743	NA	0.02485462	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.277856953814921	NA	0.02485462
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	1q24.3	1	172383850	NR	PIGC, DNM3	NA	NA	ENSG00000135845, ENSG00000197959	NA	NA	rs714515-A	rs714515	0	714515	intron_variant	FALSE	0.573760826852533	3e-16	15.522878745280337	NA	0.02717696	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.573760826852533	NA	0.02717696
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	1q41	1	219471154	NR	LYPLAL1-AS1 - NA	ENSG00000228536	NA	NA	11785	NA	rs2605101-A	rs2605101	0	2605101	intergenic_variant	TRUE	0.676330377743423	1e-21	21	NA	0.03778358	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.676330377743423	NA	0.03778358
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	2p14	2	65984655	NR	NA	NA	NA	NA	NA	NA	rs10210513-A	rs10210513	0	10210513	intron_variant	TRUE	0.855921310793251	4e-10	9.397940008672037	NA	0.029621748	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.855921310793251	NA	0.029621748
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	2q24.3	2	164656581	NR	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs10195252-T	rs10195252	0	10195252	intron_variant	FALSE	0.590334060130194	6e-15	14.221848749616356	NA	0.026324013	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.590334060130194	NA	0.026324013
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	2q32.1	2	187218396	NR	RN7SKP42 - RNU6-989P	ENSG00000222845	ENSG00000199626	NA	95535	52302	rs13424740-T	rs13424740	0	13424740	intron_variant	TRUE	0.529034400293698	2e-12	11.698970004336019	NA	0.022926193	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.529034400293698	NA	0.022926193
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	3p25.2	3	12292917	NR	PPARG	NA	NA	ENSG00000132170	NA	NA	rs2972164-T	rs2972164	0	2972164	intron_variant	FALSE	0.460702141477614	2e-8	7.698970004336019	NA	0.018405639	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.460702141477614	NA	0.018405639
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	3p25.2	3	12447843	NR	PPARG - TSEN2	ENSG00000132170	ENSG00000154743	NA	13487	36578	rs17819328-T	rs17819328	0	17819328	intergenic_variant	TRUE	0.568866821787217	1e-7	7	NA	0.018419184	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.568866821787217	NA	0.018419184
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	3p21.2	3	52254929	NR	WDR82	NA	NA	ENSG00000164091	NA	NA	rs1060330-T	rs1060330	0	1060330	3_prime_UTR_variant	FALSE	0.494155726283807	3e-8	7.522878745280337	NA	0.018098544	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.494155726283807	NA	0.018098544
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	3p21.1	3	52532998	NR	NT5DC2	NA	NA	ENSG00000168268	NA	NA	rs12489828-T	rs12489828	0	12489828	intron_variant	FALSE	0.549420159198893	2e-11	10.698970004336019	NA	0.022019453	units decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.549420159198893	NA	0.022019453
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	rs2710323-T	rs2710323	0	2710323	NA	TRUE	0.508618171719219	7e-12	11.154901959985743	NA	0.022739816	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.508618171719219	NA	0.022739816
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	3p14.1	3	64716214	NR	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs4504165-T	rs4504165	0	4504165	intron_variant	FALSE	0.703113195665242	5e-18	17.30102999566398	NA	0.032882467	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.703113195665242	NA	0.032882467
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	3q22.1	3	129615390	NR	PLXND1 - TMCC1	ENSG00000004399	ENSG00000172765	NA	8714	32402	rs10804591-A	rs10804591	0	10804591	intergenic_variant	TRUE	0.793416064960674	1e-8	8	NA	0.023304546	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.793416064960674	NA	0.023304546
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	3q25.31	3	157080505	NR	LEKR1 - LINC00880	ENSG00000197980	ENSG00000243629	NA	34376	1162	rs1482852-A	rs1482852	0	1482852	intergenic_variant	TRUE	0.597302751052095	6e-14	13.221848749616356	NA	0.026141942	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.597302751052095	NA	0.026141942
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	4q28.1	4	123145793	NR	SPATA5	NA	NA	ENSG00000145375	NA	NA	rs303084-A	rs303084	0	303084	intron_variant	FALSE	0.79545236333131	5e-9	8.301029995663981	NA	0.023823267	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.79545236333131	NA	0.023823267
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	83915207	ADAMTSL3	ADAMTSL3	NA	NA	ENSG00000156218	NA	NA	rs2030839-C	rs2030839	0	2030839	intron_variant	FALSE	0.5211	7e-15	14.154901959985743	(EA, men)	0.0435	[0.033-0.054] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5211	NA	0.0435
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q11.2	17	30837005	ATAD5	ATAD5	NA	NA	ENSG00000176208	NA	NA	rs3764419-C	rs3764419	0	3764419	intron_variant	FALSE	0.6093	4e-8	7.3979400086720375	(EA, men)	0.0317	[0.02-0.043] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6093	NA	0.0317
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q23.2	17	61419916	C17orf82	LINC02875 - TBX4	ENSG00000187013	ENSG00000121075	NA	6636	32488	rs757608-A	rs757608	0	757608	regulatory_region_variant	TRUE	0.3207	9e-6	5.045757490560675	(EA, men)	0.0265	[0.015-0.038] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3207	NA	0.0265
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	18q11.2	18	23151966	CABLES1	CABLES1	NA	NA	ENSG00000134508	NA	NA	rs4239436-G	rs4239436	0	4239436	intron_variant	FALSE	0.7888999999999999	2e-11	10.698970004336019	(EA, men)	0.0455	[0.032-0.059] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7888999999999999	NA	0.0455
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118321979	SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126	NA	57490	292354	rs7536458-T	rs7536458	0	7536458	intergenic_variant	TRUE	0.7428	6e-7	6.221848749616356	(EA, women)	0.0279	[0.017-0.039] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7428	NA	0.0279
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118961220	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs984222-G	rs984222	0	984222	intron_variant	FALSE	0.6225	8e-15	14.096910013008056	(EA, women)	0.0384	[0.029-0.048] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6225	NA	0.0384
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q21.2	1	149934520	MTMR11	MTMR11	NA	NA	ENSG00000014914	NA	NA	rs11205303-C	rs11205303	0	11205303	missense_variant	FALSE	0.3839	8e-9	8.096910013008056	(EA, women)	0.031	[0.02-0.042] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3839	NA	0.031
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q24.3	1	172361919	DNM3	DNM3	NA	NA	ENSG00000197959	NA	NA	rs1894633-G	rs1894633	0	1894633	intron_variant	FALSE	0.3388	2e-10	9.698970004336019	(EA, women)	0.0332	[0.023-0.043] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3388	NA	0.0332
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.3	1	184049341	 TSEN15	COLGALT2 - TSEN15	ENSG00000198756	ENSG00000198860	NA	11612	2310	rs1926872-C	rs1926872	0	1926872	intergenic_variant	TRUE	0.35229999999999995	7e-9	8.154901959985743	(EA, women)	0.0352	[0.023-0.047] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.35229999999999995	NA	0.0352
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p23.3	2	25263901	DNMT3A	DNMT3A	NA	NA	ENSG00000119772	NA	NA	rs12991495-T	rs12991495	0	12991495	intron_variant	FALSE	0.692	9e-6	5.045757490560675	(EA, women)	0.0251	[0.014-0.036] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.692	NA	0.0251
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2q24.3	2	164656581	GRB14, COBLL1	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs10195252-T	rs10195252	0	10195252	intron_variant	FALSE	0.5932	2e-13	12.698970004336019	(EA, women)	0.0378	[0.028-0.048] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5932	NA	0.0378
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p21.1	3	52615732	PBRM1	PBRM1	NA	NA	ENSG00000163939	NA	NA	rs13083798-A	rs13083798	0	13083798	intron_variant	FALSE	0.4905	2e-11	10.698970004336019	(EA, women)	0.0325	[0.023-0.042] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.4905	NA	0.0325
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p14.1	3	64744216	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs7638389-A	rs7638389	0	7638389	intron_variant	FALSE	0.7481	6e-13	12.221848749616356	(EA, women)	0.0407	[0.03-0.052] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7481	NA	0.0407
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q25.31	3	157079820	LEKR1	LEKR1 - LINC00880	ENSG00000197980	ENSG00000243629	NA	33691	1847	rs17451107-T	rs17451107	0	17451107	regulatory_region_variant	TRUE	0.6097	8e-13	12.096910013008056	(EA, women)	0.0368	[0.027-0.047] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6097	NA	0.0368
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4q13.3	4	72611184	ADAMTS3	ADAMTS3 - NA	ENSG00000156140	NA	NA	41963	NA	rs16848284-C	rs16848284	0	16848284	intergenic_variant	TRUE	0.4458	9e-6	5.045757490560675	(EA, women)	0.0215	[0.012-0.031] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.4458	NA	0.0215
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4q21.21	4	81228677	PRKG2	PRKG2 - NA	ENSG00000138669	NA	NA	13455	NA	rs710841-T	rs710841	0	710841	intergenic_variant	TRUE	0.2519	4e-6	5.3979400086720375	(EA, women)	0.0257	[0.015-0.037] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2519	NA	0.0257
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5p13.3	5	32753566	NPR3	NPR3	NA	NA	ENSG00000113389	NA	NA	rs2062708-C	rs2062708	0	2062708	intron_variant	FALSE	0.16169999999999995	1e-6	6	(EA, women)	0.0321	[0.019-0.045] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.16169999999999995	NA	0.0321
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q11.2	5	56565039	MAP3K1	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs3936510-T	rs3936510	0	3936510	intron_variant	FALSE	0.1867	2e-12	11.698970004336019	(EA, women)	0.045	[0.032-0.058] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.1867	NA	0.045
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q35.1	5	171856465	FBXW11	SMIM23 - FBXW11	ENSG00000185662	ENSG00000072803	NA	60339	5084	rs4868126-G	rs4868126	0	4868126	regulatory_region_variant	TRUE	0.6084	4e-7	6.3979400086720375	(EA, women)	0.0261	[0.016-0.036] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6084	NA	0.0261
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q35.3	5	177100576	FGFR4	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-T	rs6556301	0	6556301	intergenic_variant	TRUE	0.3576	1e-7	7	(EA, women)	0.029	[0.018-0.04] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3576	NA	0.029
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p22.2	6	26200449	HIST1H2BF	H2BC7	NA	NA	ENSG00000277224	NA	NA	rs806794-A	rs806794	0	806794	3_prime_UTR_variant	FALSE	0.6986	8e-7	6.096910013008056	(EA, women)	0.0263	[0.016-0.037] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6986	NA	0.0263
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.31	6	34231315	CYCSL1, HMGA1	CYCSP55 - HMGA1	ENSG00000214810	ENSG00000137309	NA	11249	5558	rs2780226-C	rs2780226	0	2780226	regulatory_region_variant	TRUE	0.0816	1e-11	11	(EA, women)	0.0618	[0.044-0.08] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.0816	NA	0.0618
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.1	6	43790159	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	3672	54719	rs998584-A	rs998584	0	998584	regulatory_region_variant	TRUE	0.486	8e-24	23.096910013008056	(EA, women)	0.0542	[0.044-0.065] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.486	NA	0.0542
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q16.3	6	104916546	HACE1	LIN28B-AS1	NA	NA	ENSG00000203809	NA	NA	rs11156429-T	rs11156429	0	11156429	intron_variant	FALSE	0.4566	2e-6	5.698970004336019	(EA, women)	0.0232	[0.014-0.033] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.4566	NA	0.0232
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q22.33	6	127115500	RSPO3	NA - RSPO3	NA	ENSG00000146374	NA	NA	3171	rs1555091-A	rs1555091	0	1555091	intron_variant	TRUE	0.2617	3e-11	10.522878745280337	(EA, women)	0.0367	[0.026-0.047] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2617	NA	0.0367
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q24.2	6	142382740	GPR126	ADGRG6	NA	NA	ENSG00000112414	NA	NA	rs4896582-G	rs4896582	0	4896582	intron_variant	FALSE	0.6960999999999999	2e-6	5.698970004336019	(EA, women)	0.0252	[0.015-0.035] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6960999999999999	NA	0.0252
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	25821192	UBA52P1	NA	NA	NA	NA	NA	NA	rs7798431-A	rs7798431	0	7798431	TF_binding_site_variant	TRUE	0.2505	2e-11	10.698970004336019	(EA, women)	0.0381	[0.027-0.049] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2505	NA	0.0381
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.1	7	28150327	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs1708299-A	rs1708299	0	1708299	intron_variant	FALSE	0.2994	3e-7	6.522878745280337	(EA, women)	0.027	[0.017-0.037] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2994	NA	0.027
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7q32.2	7	130373797	CPA5	CPA5 - CPA1	ENSG00000158525	ENSG00000091704	NA	5067	6542	rs1465370-G	rs1465370	0	1465370	regulatory_region_variant	TRUE	0.6767000000000001	3e-8	7.522878745280337	(EA, women)	0.0318	[0.02-0.043] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6767000000000001	NA	0.0318
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	8p21.2	8	23745811	NKX2-6	NKX2-6 - STC1	ENSG00000180053	ENSG00000159167	NA	39055	96118	rs7830933-A	rs7830933	0	7830933	intron_variant	TRUE	0.7625	4e-9	8.397940008672037	(EA, women)	0.0333	[0.022-0.044] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7625	NA	0.0333
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	10q22.3	10	79147390	ZMIZ1	ZMIZ1	NA	NA	ENSG00000108175	NA	NA	rs780159-G	rs780159	0	780159	intron_variant	FALSE	0.5817	2e-6	5.698970004336019	(EA, women)	0.0236	[0.014-0.033] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5817	NA	0.0236
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	11q13.5	11	75565133	SERPINH1	SERPINH1	NA	NA	ENSG00000149257	NA	NA	rs606452-A	rs606452	0	606452	intron_variant	FALSE	0.1447	2e-6	5.698970004336019	(EA, women)	0.0335	[0.02-0.047] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.1447	NA	0.0335
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12p11.23	12	26300350	ITPR2, SSPN	SSPN - ITPR2	ENSG00000123096	ENSG00000123104	NA	1060	35002	rs718314-G	rs718314	0	718314	intron_variant	TRUE	0.2551	1e-9	9	(EA, women)	0.0338	[0.023-0.045] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2551	NA	0.0338
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12p11.22	12	28318386	CCDC91	CCDC91	NA	NA	ENSG00000123106	NA	NA	rs10843151-G	rs10843151	0	10843151	intron_variant	FALSE	0.6889000000000001	2e-7	6.698970004336019	(EA, women)	0.032	[0.02-0.044] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6889000000000001	NA	0.032
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q13.13	12	53991815	MIR196A2	MIR196A2, HOXC6	NA	NA	ENSG00000207924, ENSG00000197757	NA	NA	rs11614913-T	rs11614913	0	11614913	non_coding_transcript_exon_variant	FALSE	0.415	4e-8	7.3979400086720375	(EA, women)	0.0313	[0.02-0.042] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.415	NA	0.0313
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q24.31	12	123935181	DNAH10	DNAH10, CCDC92	NA	NA	ENSG00000197653, ENSG00000119242	NA	NA	rs11057397-C	rs11057397	0	11057397	intron_variant	FALSE	0.6614	2e-13	12.698970004336019	(EA, women)	0.0374	[0.027-0.047] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6614	NA	0.0374
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	83845538	ADAMTSL3	ADAMTSL3	NA	NA	ENSG00000156218	NA	NA	rs7162542-G	rs7162542	0	7162542	intron_variant	FALSE	0.5582	8e-15	14.096910013008056	(EA, women)	0.0381	[0.028-0.048] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5582	NA	0.0381
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q26.1	15	88871064	ACAN	ACAN	NA	NA	ENSG00000157766	NA	NA	rs1879529-G	rs1879529	0	1879529	intron_variant	FALSE	0.7214	1e-7	7	(EA, women)	0.0295	[0.019-0.04] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7214	NA	0.0295
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17p13.3	17	560603	VPS53	VPS53, VPS53	NA	NA	ENSG00000141252, ENSG00000283883	NA	NA	rs741677-A	rs741677	0	741677	intron_variant	FALSE	0.5798	8e-6	5.096910013008056	(EA, women)	0.0241	[0.014-0.035] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5798	NA	0.0241
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q23.2	17	61419916	C17orf82	LINC02875 - TBX4	ENSG00000187013	ENSG00000121075	NA	6636	32488	rs757608-A	rs757608	0	757608	regulatory_region_variant	TRUE	0.3207	1e-6	6	(EA, women)	0.0253	[0.015-0.035] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3207	NA	0.0253
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	18q11.2	18	23151966	CABLES1	CABLES1	NA	NA	ENSG00000134508	NA	NA	rs4239436-G	rs4239436	0	4239436	intron_variant	FALSE	0.7888999999999999	4e-9	8.397940008672037	(EA, women)	0.0353	[0.024-0.047] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7888999999999999	NA	0.0353
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	20p12.3	20	6610469	LOC149844, BMP2	CASC20 - RALY	ENSG00000229876	ENSG00000125970	NA	82010	27383177	rs6107848-A	rs6107848	0	6107848	intergenic_variant	TRUE	0.3631	3e-8	7.522878745280337	(EA, women)	0.0282	[0.018-0.038] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3631	NA	0.0282
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p36.13	1	16981663	MFAP2	MFAP2 - ATP13A2	ENSG00000117122	ENSG00000159363	NA	1031	4295	rs9435732-C	rs9435732	0	9435732	intron_variant	TRUE	0.7313000000000001	8e-13	12.096910013008056	(EA)	0.0303	[0.022-0.039] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7313000000000001	NA	0.0303
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118321979	SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126	NA	57490	292354	rs7536458-T	rs7536458	0	7536458	intergenic_variant	TRUE	0.7428	3e-14	13.522878745280337	(EA)	0.0327	[0.024-0.041] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7428	NA	0.0327
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118961220	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs984222-G	rs984222	0	984222	intron_variant	FALSE	0.6225	2e-24	23.69897000433602	(EA)	0.0392	[0.032-0.047] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6225	NA	0.0392
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q21.2	1	149934520	MTMR11	MTMR11	NA	NA	ENSG00000014914	NA	NA	rs11205303-C	rs11205303	0	11205303	missense_variant	FALSE	0.3839	8e-14	13.096910013008056	(EA)	0.031	[0.023-0.039] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3839	NA	0.031
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q24.3	1	172361919	DNM3	DNM3	NA	NA	ENSG00000197959	NA	NA	rs1894633-G	rs1894633	0	1894633	intron_variant	FALSE	0.3388	6e-11	10.221848749616356	(EA)	0.0261	[0.018-0.034] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3388	NA	0.0261
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.3	1	184054395	 TSEN15	TSEN15	NA	NA	ENSG00000198860	NA	NA	rs1046934-C	rs1046934	0	1046934	missense_variant	FALSE	0.35729999999999995	4e-12	11.397940008672037	(EA)	0.0273	[0.02-0.035] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.35729999999999995	NA	0.0273
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q41	1	218451191	TGFB2, LYPLAL1	TGFB2 - LINC02869	ENSG00000092969	ENSG00000228208	NA	6572	8074	rs10429950-C	rs10429950	0	10429950	intergenic_variant	TRUE	0.2791	5e-13	12.301029995663981	(EA)	0.03	[0.022-0.038] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2791	NA	0.03
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p23.3	2	25263901	DNMT3A	DNMT3A	NA	NA	ENSG00000119772	NA	NA	rs12991495-T	rs12991495	0	12991495	intron_variant	FALSE	0.692	2e-10	9.698970004336019	(EA)	0.0272	[0.019-0.036] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.692	NA	0.0272
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p13	20	159200	NR	DEFB127 - DEFB128; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4142303-A; rs4142304-C; rs6077288-G; rs6055356-C; rs6086092-T; rs2298108-T; rs1858594-C; rs16995685-A; rs6039029-G; rs12624951-A; rs6039035-C; rs11087789-C; rs1434790-G; rs2298109-T; rs6086352-G; rs6038867-T	rs4142303; rs4142304; rs6077288; rs6055356; rs6086092; rs2298108; rs1858594; rs16995685; rs6039029; rs12624951; rs6039035; rs11087789; rs1434790; rs2298109; rs6086352; rs6038867	0	NA	intergenic_variant; 3_prime_UTR_variant; intron_variant; intergenic_variant; intergenic_variant; 5_prime_UTR_variant; intron_variant; missense_variant; intergenic_variant; splice_region_variant; intergenic_variant; intron_variant; intergenic_variant; 5_prime_UTR_variant; intergenic_variant; intergenic_variant	NA	0.351	1e-20	20	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.351	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p13	20	423763	NR	TBC1D20; RBCK1; No mapped genes	NA	NA	NA	NA	NA	rs6107303-T; rs6051908-G	rs6107303; rs6051908	0	NA	3_prime_UTR_variant; intron_variant	NA	0.006	7e-26	25.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.006	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p13	20	423763	NR	TBC1D20; RBCK1; No mapped genes	NA	NA	NA	NA	NA	rs6107303-T; rs6051908-T	rs6107303; rs6051908	0	NA	3_prime_UTR_variant; intron_variant	NA	0.286	6e-13	12.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.286	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p13	20	706757	NR	SCRT2 - SLC52A3; No mapped genes	NA	NA	NA	NA	NA	rs6038447-C; rs6139971-T	rs6038447; rs6139971	0	NA	intergenic_variant; intergenic_variant	NA	0.167	4e-9	8.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.167	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p13	20;20	1131525;1135786	NR	PSMF1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; PSMF1; No mapped genes	NA	NA	NA	NA	NA	rs2284371-A; rs3787573-A; rs6514115-A; rs6074148-C; rs4289256-G; rs6077860-A; rs2284372-T	rs2284371; rs3787573; rs6514115; rs6074148; rs4289256; rs6077860; rs2284372	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	1e-8	8	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p13	20	4474366	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs17227126-T; rs6116371-T; rs3907202-A; rs4465845-A; rs297660-C; rs6037853-C; rs979073-C; rs1382033-G	rs17227126; rs6116371; rs3907202; rs4465845; rs297660; rs6037853; rs979073; rs1382033	0	NA	intergenic_variant; intergenic_variant; TF_binding_site_variant; intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant	NA	0.154	7e-8	7.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.154	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p13	20	5043692	NR	SLC23A2 - TMEM230; No mapped genes	NA	NA	NA	NA	NA	rs6038044-G; rs404678-C	rs6038044; rs404678	0	NA	intergenic_variant; intergenic_variant	NA	0.393	1e-21	21	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.393	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p13	20	5043692	NR	SLC23A2 - TMEM230; No mapped genes	NA	NA	NA	NA	NA	rs6038044-G; rs404678-T	rs6038044; rs404678	0	NA	intergenic_variant; intergenic_variant	NA	0.255	2e-13	12.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.255	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.3	20;20	5335443;5336940	NR	PROKR2 - RNA5-8SP7; PROKR2 - RNA5-8SP7; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs6053319-C; rs2145095-G; rs6107619-G; rs17721514-A; rs6085111-G; rs2103974-G	rs6053319; rs2145095; rs6107619; rs17721514; rs6085111; rs2103974	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.119	7e-6	5.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.119	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.3	20	5392434	NR	RNA5-8SP7 - LINC00658; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs17721798-C; rs6076827-A; rs6053352-G; rs7267662-C; rs6053353-G; rs11699382-A; rs4815805-C	rs17721798; rs6076827; rs6053352; rs7267662; rs6053353; rs11699382; rs4815805	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.002	3e-7	6.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.002	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.3	20	8784632	NR	PLCB1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4816085-G; rs6039266-A; rs4633993-C; rs718711-C; rs6039268-C; rs2327088-A; rs6086595-C; rs6133621-T; rs6086591-G; rs2076411-T; rs6039267-C; rs17376808-T; rs718712-G	rs4816085; rs6039266; rs4633993; rs718711; rs6039268; rs2327088; rs6086595; rs6133621; rs6086591; rs2076411; rs6039267; rs17376808; rs718712	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.2	20	10128293	NR	SNAP25-AS1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs510915-C; rs510734-C; rs644028-C; rs663250-G; rs6077654-T; rs3761161-G; rs543895-T; rs2064655-G; rs570383-C; rs586791-G; rs509110-T; rs12624858-C; rs555185-C; rs6133806-C; rs4813912-G	rs510915; rs510734; rs644028; rs663250; rs6077654; rs3761161; rs543895; rs2064655; rs570383; rs586791; rs509110; rs12624858; rs555185; rs6133806; rs4813912	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.002	7e-16	15.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.002	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.2	20	10128293	NR	SNAP25-AS1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs510915-T; rs510734-C; rs644028-C; rs663250-G; rs6077654-T; rs3761161-G; rs543895-T; rs2064655-G; rs570383-C; rs586791-G; rs509110-T; rs12624858-C; rs555185-C; rs6133806-C; rs4813912-G	rs510915; rs510734; rs644028; rs663250; rs6077654; rs3761161; rs543895; rs2064655; rs570383; rs586791; rs509110; rs12624858; rs555185; rs6133806; rs4813912	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.15	2e-7	6.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.15	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.2	20	10335578	NR	SNAP25-AS1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs6108479-A; rs1540902-A; rs362557-C; rs12625867-C; rs11087010-G; rs11087009-T; rs6133869-C; rs6104580-T	rs6108479; rs1540902; rs362557; rs12625867; rs11087010; rs11087009; rs6133869; rs6104580	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	9e-21	20.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.2	20	10335578	NR	SNAP25-AS1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs6108479-A; rs1540902-A; rs362557-C; rs12625867-T; rs11087010-G; rs11087009-T; rs6133869-C; rs6104580-T	rs6108479; rs1540902; rs362557; rs12625867; rs11087010; rs11087009; rs6133869; rs6104580	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.187	7e-10	9.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.187	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.2	20	11928203	NR	BTBD3 - N/A; No mapped genes	NA	NA	NA	NA	NA	rs6074369-A; rs1883791-C	rs6074369; rs1883791	0	NA	intergenic_variant; intergenic_variant	NA	0.189	6e-9	8.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.189	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.2	20	11928203	NR	BTBD3 - N/A; No mapped genes	NA	NA	NA	NA	NA	rs6074369-G; rs1883791-C	rs6074369; rs1883791	0	NA	intergenic_variant; intergenic_variant	NA	0.582	1e-6	6	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.582	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.1	20	12000348	NR	BTBD3 - N/A; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2206804-C; rs12626103-T; rs12626037-T; rs17190199-A; rs6041020-C; rs6131288-C	rs2206804; rs12626103; rs12626037; rs17190199; rs6041020; rs6131288	0	NA	intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; regulatory_region_variant	NA	0.0	2e-13	12.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.1	20	12000348	NR	BTBD3 - N/A; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2206804-C; rs12626103-T; rs12626037-T; rs17190199-A; rs6041020-T; rs6131288-C	rs2206804; rs12626103; rs12626037; rs17190199; rs6041020; rs6131288	0	NA	intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; regulatory_region_variant	NA	0.171	2e-9	8.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.171	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.1	20	14705863	NR	MACROD2; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11908351-A; rs11907538-C; rs17775664-T; rs10485775-T	rs11908351; rs11907538; rs17775664; rs10485775	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.314	6e-15	14.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.314	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.1	20	14705863	NR	MACROD2; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11908351-A; rs11907538-C; rs17775664-G; rs10485775-T	rs11908351; rs11907538; rs17775664; rs10485775	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.419	5e-8	7.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.419	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.1	20	15301802	NR	MACROD2; No mapped genes	NA	NA	NA	NA	NA	rs6043194-G; rs6043189-G	rs6043194; rs6043189	0	NA	intron_variant; intron_variant	NA	0.18	4e-14	13.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.18	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.1	20	15301802	NR	MACROD2; No mapped genes	NA	NA	NA	NA	NA	rs6043194-A; rs6043189-G	rs6043194; rs6043189	0	NA	intron_variant; intron_variant	NA	0.27	4e-12	11.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.27	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p12.1	20	17376380	NR	PCSK2; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs6075201-C; rs6034809-G; rs11696192-G; rs6080665-C; rs4814615-G; rs12106074-A; rs4814616-G; rs16999051-T; rs6034810-A; rs11698484-C; rs6044770-T	rs6075201; rs6034809; rs11696192; rs6080665; rs4814615; rs12106074; rs4814616; rs16999051; rs6034810; rs11698484; rs6044770	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	8e-6	5.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p11.23	20	19014188	NR	No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4814820-A; rs8124833-C; rs8113962-T	rs4814820; rs8124833; rs8113962	0	NA	intron_variant; intron_variant; intron_variant	NA	0.148	2e-7	6.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.148	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q23	3	141529673	RASA2	RASA2	NA	NA	ENSG00000155903	NA	NA	rs79308158-G	rs79308158	0	79308158	intron_variant	FALSE	0.0712	2e-15	14.698970004336019	NA	0.05473161	[0.041-0.068] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.0712	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q23	3	142114139	TFDP2	TFDP2	NA	NA	ENSG00000114126	NA	NA	rs62284572-T	rs62284572	0	62284572	intron_variant	FALSE	0.1974	6e-9	8.221848749616356	NA	0.02596429	[0.017-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.1974	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q23	3	142601690	PLS1	PLS1	NA	NA	ENSG00000120756	NA	NA	rs7428496-T	rs7428496	0	7428496	intron_variant	FALSE	0.585	3e-60	59.52287874528034	NA	0.05879796	[0.052-0.066] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.585	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q26.32	3	179022634	ZMAT3	ZMAT3	NA	NA	ENSG00000172667	NA	NA	rs7641761-A	rs7641761	0	7641761	3_prime_UTR_variant	FALSE	0.6978	3e-10	9.522878745280337	NA	0.02431824	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.6978	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q29	3	196065999	TFRC	TFRC	NA	NA	ENSG00000072274	NA	NA	rs3789135-A	rs3789135	0	3789135	intron_variant	FALSE	0.6132	1e-83	83	NA	0.07033563	[0.063-0.077] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.6132	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q29	3	196107432	intergenic	TFRC - LINC00885	ENSG00000072274	ENSG00000224652	NA	25336	35093	rs9816784-C	rs9816784	0	9816784	intergenic_variant	TRUE	0.5241	4e-98	97.39794000867204	NA	0.07473334	[0.068-0.082] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.5241	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q29	3	196128111	intergenic	TFRC - LINC00885	ENSG00000072274	ENSG00000224652	NA	46015	14414	rs7617390-C	rs7617390	0	7617390	regulatory_region_variant	TRUE	0.1777	3e-40	39.52287874528034	NA	0.06391008	[0.054-0.073] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.1777	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q29	3	196179876	intergenic	LINC00885 - ZDHHC19	ENSG00000224652	ENSG00000163958	NA	18983	17576	rs28429906-G	rs28429906	0	28429906	TF_binding_site_variant	TRUE	0.1959	5e-34	33.30102999566398	NA	0.05503497	[0.046-0.064] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.1959	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q29	3	196195556	ZDHHC19	LINC00885 - ZDHHC19	ENSG00000224652	ENSG00000163958	NA	34663	1896	rs9850274-G	rs9850274	0	9850274	intergenic_variant	TRUE	0.7082	5e-54	53.30102999566398	NA	0.06081938	[0.053-0.069] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.7082	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	4p15.32	4	15601446	CC2D2A	CC2D2A	NA	NA	ENSG00000048342	NA	NA	rs1134634-C	rs1134634	0	1134634	3_prime_UTR_variant	FALSE	0.577	3e-18	17.522878745280337	NA	0.0313188	[0.024-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.577	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	4p14	4	38607291	intergenic	KLF3-AS1	NA	NA	ENSG00000231160	NA	NA	rs6855993-T	rs6855993	0	6855993	intron_variant	FALSE	0.2126	3e-10	9.522878745280337	NA	0.02730825	[0.019-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2126	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	4p14	4	39364100	RFC1	RFC1	NA	NA	ENSG00000035928	NA	NA	rs78773383-G	rs78773383	0	78773383	intron_variant	FALSE	0.5416	2e-12	11.698970004336019	NA	0.02522975	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.5416	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	NA	NA	NA	intergenic	NA	NA	NA	NA	NA	NA	chr4:55392250-G	chr4:55392250	0	NA	NA	TRUE	0.094	1e-10	10	NA	0.0391184	[0.027-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.094	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	4q12	4	54542832	intergenic	LINC02283 - LINC02260	ENSG00000248184	ENSG00000250456	NA	186878	60379	rs218265-C	rs218265	0	218265	intergenic_variant	TRUE	0.1572	2e-169	168.69897000433602	NA	0.1367009	[0.13-0.15] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.1572	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	4q13.2	4	68516682	UGT2B29P	UGT2B29P, UGT2B29P	NA	NA	ENSG00000250566, ENSG00000281547	NA	NA	rs546475500-G	rs546475500	0	546475500	intron_variant	FALSE	0.2906	4e-9	8.397940008672037	NA	0.02627355	[0.018-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2906	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	4q21.3	4	87054903	AFF1	AFF1	NA	NA	ENSG00000172493	NA	NA	rs443459-A	rs443459	0	443459	intron_variant	FALSE	0.2616	9e-15	14.045757490560675	NA	0.03119863	[0.023-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2616	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	4q27	4	121808259	EXOSC9	EXOSC9	NA	NA	ENSG00000123737	NA	NA	rs33964027-C	rs33964027	0	33964027	intron_variant	FALSE	0.3967	6e-18	17.221848749616356	NA	0.03129383	[0.024-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.3967	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	4q28.1	4	127647811	INTU	INTU	NA	NA	ENSG00000164066	NA	NA	rs181743661-T	rs181743661	0	181743661	intron_variant	FALSE	0.0085	3e-9	8.522878745280337	NA	0.1167006	[0.078-0.155] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.0085	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	4q31.21	4	144114635	GYPA, GYPB, RP11-673E1.4	GYPA	NA	NA	ENSG00000170180	NA	NA	rs6857303-A	rs6857303	0	6857303	intron_variant	FALSE	0.4555	6e-13	12.221848749616356	NA	0.02599851	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.4555	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	5p15.33	5	1286401	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs2736100-A	rs2736100	0	2736100	3_prime_UTR_variant	FALSE	0.4982	5e-34	33.30102999566398	NA	0.04294034	[0.036-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.4982	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	5q13.1	5	68300260	PIK3R1	PIK3R1	NA	NA	ENSG00000145675	NA	NA	rs3756668-A	rs3756668	0	3756668	3_prime_UTR_variant	FALSE	0.4593	4e-17	16.397940008672037	NA	0.02984507	[0.023-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.4593	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	5q14.3	5	88895818	MEF2C-AS1, MEF2C	MEF2C-AS1, MEF2C	NA	NA	ENSG00000248309, ENSG00000081189	NA	NA	rs2067663-T	rs2067663	0	2067663	intron_variant	FALSE	0.2213	7e-16	15.154901959985743	NA	0.03452001	[0.026-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2213	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	5q33.2	5	154655677	intergenic	MIR3141 - MIR1303	ENSG00000264760	ENSG00000221552	NA	59605	30099	rs35998524-T	rs35998524	0	35998524	intergenic_variant	TRUE	0.096	1e-43	43	NA	0.08383663	[0.072-0.096] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.096	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	5q33.2	5	154655826	intergenic	MIR3141 - MIR1303	ENSG00000264760	ENSG00000221552	NA	59754	29950	rs5872391-G	rs5872391	0	5872391	intergenic_variant	TRUE	0.3276	7e-41	40.15490195998574	NA	0.05085245	[0.043-0.058] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.3276	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	5q33.2	5	154973452	MRPL22	MRPL22 - KIF4B	ENSG00000082515	ENSG00000226650	NA	4041	40303	rs13165424-G	rs13165424	0	13165424	intergenic_variant	TRUE	0.252	1e-28	28	NA	0.04552891	[0.038-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.252	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	8q24.3	8	143913053	Intergenic	EPPK1 - PLEC	ENSG00000261150	ENSG00000178209	NA	34586	2100	rs6990361-T	rs6990361	0	6990361	intergenic_variant	TRUE	0.377	1e-6	6	NA	0.047	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.377	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	8q24.3	8	143912625	Intergenic	EPPK1 - PLEC	ENSG00000261150	ENSG00000178209	NA	34158	2528	rs3923387-T	rs3923387	0	3923387	regulatory_region_variant	TRUE	0.378	1e-6	6	NA	0.047	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.378	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144524542	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	47696	rs7658614-A	rs7658614	0	7658614	intron_variant	TRUE	0.595	1e-7	7	NA	0.048	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.595	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144370054	Intergenic	NA	NA	NA	NA	NA	NA	rs4465995-T	rs4465995	0	4465995	intron_variant	TRUE	0.684	2e-7	6.698970004336019	NA	0.048	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.684	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78727810	Intergenic	CHRNB4 - ADAMTS7	ENSG00000117971	ENSG00000136378	NA	56	31396	rs35583595-C	rs35583595	0	35583595	intron_variant	TRUE	0.619	4e-7	6.3979400086720375	NA	0.048	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.619	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88880152	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs62308745-T	rs62308745	0	62308745	intron_variant	FALSE	0.7	6e-7	6.221848749616356	NA	0.048	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.7	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78793573	ADAMTS7	ADAMTS7	NA	NA	ENSG00000136378	NA	NA	rs11631955-A	rs11631955	0	11631955	intron_variant	FALSE	0.593	7e-7	6.154901959985743	NA	0.048	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.593	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78703459	Intergenic	CHRNB4	NA	NA	ENSG00000117971	NA	NA	rs12324870-T	rs12324870	0	12324870	intron_variant	FALSE	0.317	7e-7	6.154901959985743	NA	0.048	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.317	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144387147	Intergenic	STX18 - NA	ENSG00000168818	NA	NA	139844801	NA	rs1505766-T	rs1505766	0	1505766	intron_variant	TRUE	0.276	9e-7	6.045757490560675	NA	0.048	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.276	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144381003	Intergenic	NA	NA	NA	NA	NA	NA	rs1394998-T	rs1394998	0	1394998	intron_variant	TRUE	0.725	9e-7	6.045757490560675	NA	0.048	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.725	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78730273	Intergenic	CHRNB4 - ADAMTS7	ENSG00000117971	ENSG00000136378	NA	2519	28933	rs8027972-T	rs8027972	0	8027972	intron_variant	TRUE	0.645	1e-6	6	NA	0.048	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.645	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88887588	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs10033824-T	rs10033824	0	10033824	intron_variant	FALSE	0.746	2e-6	5.698970004336019	NA	0.048	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.746	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78468576	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs4887057-A	rs4887057	0	4887057	intron_variant	FALSE	0.421	4e-8	7.3979400086720375	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.421	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144530761	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	41477	rs4835639-T	rs4835639	0	4835639	intron_variant	TRUE	0.603	6e-8	7.221848749616356	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.603	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144342862	Intergenic	NA	NA	NA	NA	NA	NA	rs6840871-T	rs6840871	0	6840871	intron_variant	TRUE	0.315	1e-7	7	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.315	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144349715	Intergenic	NA	NA	NA	NA	NA	NA	rs987246-T	rs987246	0	987246	intron_variant	TRUE	0.685	1e-7	7	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.685	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88884818	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs62308746-T	rs62308746	0	62308746	intron_variant	FALSE	0.702	3e-7	6.522878745280337	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.702	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88898156	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs7668636-T	rs7668636	0	7668636	intron_variant	FALSE	0.7	3e-7	6.522878745280337	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.7	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88918689	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs4693976-T	rs4693976	0	4693976	intron_variant	FALSE	0.422	3e-7	6.522878745280337	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.422	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78725343	Intergenic	CHRNB4	NA	NA	ENSG00000117971	NA	NA	rs8038543-A	rs8038543	0	8038543	intron_variant	FALSE	0.618	3e-7	6.522878745280337	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.618	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88899639	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs28529050-A	rs28529050	0	28529050	intron_variant	FALSE	0.7	3e-7	6.522878745280337	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.7	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144426946	Intergenic	NA	NA	NA	NA	NA	NA	rs12499537-T	rs12499537	0	12499537	intron_variant	TRUE	0.3	3e-7	6.522878745280337	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.3	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78724939	Intergenic	CHRNB4	NA	NA	ENSG00000117971	NA	NA	rs76919723-T	rs76919723	0	76919723	intron_variant	FALSE	0.623	5e-7	6.301029995663981	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.623	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78728695	Intergenic	CHRNB4 - ADAMTS7	ENSG00000117971	ENSG00000136378	NA	941	30511	rs2869554-T	rs2869554	0	2869554	intron_variant	TRUE	0.632	7e-7	6.154901959985743	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.632	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q22.2	11	102849947	Intergenic	MMP3 - MMP12	ENSG00000149968	ENSG00000262406	NA	6338	12789	rs615098-T	rs615098	0	615098	regulatory_region_variant	TRUE	0.772	2e-6	5.698970004336019	NA	0.049	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.772	NA	NA
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8q24.12	8	120848349	NR	SNTB1 - NA	ENSG00000172164	NA	NA	35076	NA	rs13248499-G	rs13248499	0	13248499	intergenic_variant	TRUE	NR	1e-11	11	NA	0.025	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.025
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	10q26.12	10	121099663	NR	NA - RPL19P16	NA	ENSG00000236762	NA	NA	33427	rs7079858-G	rs7079858	0	7079858	intergenic_variant	TRUE	0.911	2e-8	7.698970004336019	(EA)	0.037	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.911	NA	0.037
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	10q26.12	10	121099663	NR	NA - RPL19P16	NA	ENSG00000236762	NA	NA	33427	rs7079858-G	rs7079858	0	7079858	intergenic_variant	TRUE	NR	5e-8	7.301029995663981	NA	0.031	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.031
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	11p15.4	11	2937308	NR	PHLDA2 - NAP1L4	ENSG00000181649	ENSG00000205531	NA	7888	7123	rs7935422-T	rs7935422	0	7935422	intergenic_variant	TRUE	0.599	2e-8	7.698970004336019	(EA)	0.022	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.599	NA	0.022
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	11p15.4	11	2937308	NR	PHLDA2 - NAP1L4	ENSG00000181649	ENSG00000205531	NA	7888	7123	rs7935422-T	rs7935422	0	7935422	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	NA	0.02	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.02
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	11q13.1	11	64109691	NR	FLRT1, MACROD1	NA	NA	ENSG00000126500, ENSG00000133315	NA	NA	rs11231698-C	rs11231698	0	11231698	intron_variant	FALSE	NR	3e-6	5.522878745280337	NA	0.038	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.038
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	14q23.3	14	64653121	NR	NUP50P1 - PLEKHG3	ENSG00000259010	ENSG00000126822	NA	51477	50981	rs7148864-A	rs7148864	0	7148864	regulatory_region_variant	TRUE	0.796	7e-10	9.154901959985743	(EA)	0.03	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.796	NA	0.03
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	14q23.3	14	64653121	NR	NUP50P1 - PLEKHG3	ENSG00000259010	ENSG00000126822	NA	51477	50981	rs7148864-A	rs7148864	0	7148864	regulatory_region_variant	TRUE	NR	1e-8	8	NA	0.025	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.025
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr14:92498829:D-ATAT	chr14:92498829:D	0	NA	NA	TRUE	0.767	2e-7	6.698970004336019	(EA)	0.024	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.767	NA	0.024
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr14:92498829:D-ATAT	chr14:92498829:D	0	NA	NA	TRUE	NR	1e-8	8	NA	0.023	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.023
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	Xp22.2	X	14841981	NR	FANCB	NA	NA	ENSG00000181544	NA	NA	rs138331350-G	rs138331350	0	138331350	intron_variant	FALSE	0.942	3e-11	10.522878745280337	(EA)	0.048	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.942	NA	0.048
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	Xp22.2	X	14841981	NR	FANCB	NA	NA	ENSG00000181544	NA	NA	rs138331350-G	rs138331350	0	138331350	intron_variant	FALSE	NR	1e-12	12	NA	0.049	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.049
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p36.11	1	26661155	NR	RNU7-29P - ARID1A	ENSG00000252429	ENSG00000117713	NA	58723	32081	rs193084249-A	rs193084249	0	193084249	intergenic_variant	TRUE	0.98	2e-14	13.698970004336019	(EA)	0.113	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.98	NA	0.113
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p36.11	1	26661155	NR	RNU7-29P - ARID1A	ENSG00000252429	ENSG00000117713	NA	58723	32081	rs193084249-A	rs193084249	0	193084249	intergenic_variant	TRUE	NR	2e-14	13.698970004336019	NA	0.114	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.114
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p36.11	1	26811902	NR	PIGV - RN7SL165P	ENSG00000060642	ENSG00000241188	NA	11243	2920	rs12748152-C	rs12748152	0	12748152	regulatory_region_variant	TRUE	0.925	5e-13	12.301029995663981	(EA)	0.051	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.925	NA	0.051
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p36.11	1	26811902	NR	PIGV - RN7SL165P	ENSG00000060642	ENSG00000241188	NA	11243	2920	rs12748152-C	rs12748152	0	12748152	regulatory_region_variant	TRUE	NR	3e-14	13.522878745280337	NA	0.052	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.052
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p36.11	1	26958422	NR	KDF1	NA	NA	ENSG00000175707	NA	NA	rs79598313-C	rs79598313	0	79598313	intron_variant	FALSE	0.979	4e-14	13.397940008672037	(EA)	0.099	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.979	NA	0.099
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p36.11	1	26958422	NR	KDF1	NA	NA	ENSG00000175707	NA	NA	rs79598313-C	rs79598313	0	79598313	intron_variant	FALSE	NR	1e-14	14	NA	0.098	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.098
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p34.3	1	39085816	NR	MACF1	NA	NA	ENSG00000127603	NA	NA	rs72634501-T	rs72634501	0	72634501	intron_variant	FALSE	0.785	4e-8	7.3979400086720375	(EA)	0.027	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.785	NA	0.027
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p34.3	1	39085816	NR	MACF1	NA	NA	ENSG00000127603	NA	NA	rs72634501-T	rs72634501	0	72634501	intron_variant	FALSE	NR	3e-9	8.522878745280337	NA	0.027	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.027
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p34.3	1	39557105	NR	PPIEL	NA	NA	ENSG00000243970	NA	NA	rs17264866-C	rs17264866	0	17264866	intron_variant	FALSE	0.762	1e-15	15	(EA)	0.035	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.762	NA	0.035
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p34.3	1	39557105	NR	PPIEL	NA	NA	ENSG00000243970	NA	NA	rs17264866-C	rs17264866	0	17264866	intron_variant	FALSE	NR	9e-19	18.045757490560675	NA	0.037	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.037
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p34.3	1	39562508	NR	PABPC4	NA	NA	ENSG00000090621	NA	NA	rs4660293-A	rs4660293	0	4660293	non_coding_transcript_exon_variant	FALSE	0.762	1e-15	15	(EA)	0.035	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.762	NA	0.035
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p34.3	1	39562508	NR	PABPC4	NA	NA	ENSG00000090621	NA	NA	rs4660293-A	rs4660293	0	4660293	non_coding_transcript_exon_variant	FALSE	NR	9e-19	18.045757490560675	NA	0.037	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.037
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p34.3	1	39570014	NR	PABPC4, PABPC4-AS1	NA	NA	ENSG00000090621, ENSG00000228060	NA	NA	rs17513135-C	rs17513135	0	17513135	intron_variant	FALSE	0.769	1e-16	16	(EA)	0.037	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.769	NA	0.037
2017-06-21	28358029	Afshari NA	2017-03-30	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28358029	Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy.	Fuchs's corneal dystrophy	1,404 European ancestry cases, 2,564 European ancestry controls	671 European ancestry cases, 778 European ancestry controls	1p31.3	1	62317189	KANK4	KANK4	NA	NA	ENSG00000132854	NA	NA	rs79742895-?	rs79742895	0	79742895	intron_variant	FALSE	NR	1e-14	14	NA	2.09	[1.73-2.52]	Illumina [8680745] (imputed)	N	Fuchs endothelial corneal dystrophy	http://www.orpha.net/ORDO/Orphanet_98974	GCST004217	Genome-wide genotyping array	NA	2.09	NA
2017-06-21	28358029	Afshari NA	2017-03-30	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28358029	Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy.	Fuchs's corneal dystrophy	1,404 European ancestry cases, 2,564 European ancestry controls	671 European ancestry cases, 778 European ancestry controls	1q24.2	1	169091251	LINC00970, ATP1B1	LINC00970 - ATP1B1	ENSG00000203601	ENSG00000143153	NA	4246	14446	rs1200114-?	rs1200114	0	1200114	intron_variant	TRUE	NR	1e-18	18	NA	1.45	[1.34-1.58]	Illumina [8680745] (imputed)	N	Fuchs endothelial corneal dystrophy	http://www.orpha.net/ORDO/Orphanet_98974	GCST004217	Genome-wide genotyping array	NA	1.45	NA
2017-06-21	28358029	Afshari NA	2017-03-30	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28358029	Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy.	Fuchs's corneal dystrophy	1,404 European ancestry cases, 2,564 European ancestry controls	671 European ancestry cases, 778 European ancestry controls	1q25.3	1	183123365	LAMC1	LAMC1	NA	NA	ENSG00000135862	NA	NA	rs3768617-?	rs3768617	0	3768617	intron_variant	FALSE	NR	7e-16	15.154901959985743	NA	1.4084507	[1.3-1.54]	Illumina [8680745] (imputed)	N	Fuchs endothelial corneal dystrophy	http://www.orpha.net/ORDO/Orphanet_98974	GCST004217	Genome-wide genotyping array	NA	1.4084507	NA
2017-06-21	28358029	Afshari NA	2017-03-30	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28358029	Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy.	Fuchs's corneal dystrophy	1,404 European ancestry cases, 2,564 European ancestry controls	671 European ancestry cases, 778 European ancestry controls	1q31.3	1	196713817	CFH	CFH	NA	NA	ENSG00000000971	NA	NA	rs2274700-?	rs2274700	0	2274700	synonymous_variant	FALSE	NR	2e-7	6.698970004336019	NA	1.25	[1.15-1.36]	Illumina [8680745] (imputed)	N	Fuchs endothelial corneal dystrophy	http://www.orpha.net/ORDO/Orphanet_98974	GCST004217	Genome-wide genotyping array	NA	1.25	NA
2017-06-21	28358029	Afshari NA	2017-03-30	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28358029	Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy.	Fuchs's corneal dystrophy	1,404 European ancestry cases, 2,564 European ancestry controls	671 European ancestry cases, 778 European ancestry controls	11p15.5	11	772701	SLC25A22	GATD1	NA	NA	ENSG00000177225	NA	NA	rs12223324-?	rs12223324	0	12223324	intron_variant	FALSE	NR	7e-7	6.154901959985743	NA	1.2345679	[1.14-1.33]	Illumina [8680745] (imputed)	N	Fuchs endothelial corneal dystrophy	http://www.orpha.net/ORDO/Orphanet_98974	GCST004217	Genome-wide genotyping array	NA	1.2345679	NA
2017-06-21	28358029	Afshari NA	2017-03-30	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28358029	Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy.	Fuchs's corneal dystrophy	1,404 European ancestry cases, 2,564 European ancestry controls	671 European ancestry cases, 778 European ancestry controls	18q21.2	18	55729968	TCF4	TCF4 - LINC01415	ENSG00000196628	ENSG00000267325	NA	65181	46759	rs784257-?	rs784257	0	784257	intron_variant	TRUE	NR	3e-200	199.52287874528034	NA	4.94	[4.45-5.48]	Illumina [8680745] (imputed)	N	Fuchs endothelial corneal dystrophy	http://www.orpha.net/ORDO/Orphanet_98974	GCST004217	Genome-wide genotyping array	NA	4.94	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	20p13	20	1949439	RP4-684O24.5	PDYN-AS1	NA	NA	ENSG00000233896	NA	NA	rs5839925-C	rs5839925	0	5839925	intron_variant	FALSE	0.34	4e-26	25.397940008672037	NA	0.04013052	[0.033-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.34	NA	0.04013052
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	20q11.21	20	32792395	DNMT3B	DNMT3B	NA	NA	ENSG00000088305	NA	NA	rs1040555-T	rs1040555	0	1040555	intron_variant	FALSE	0.4449	1e-10	10	NA	0.02319633	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4449	NA	0.02319633
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	20q13.12	20	44188394	JPH2	JPH2 - OSER1	ENSG00000149596	ENSG00000132823	NA	1206	7545	rs11469915-C	rs11469915	1	11469764	TF_binding_site_variant	TRUE	0.3525	9e-11	10.045757490560675	NA	0.02435906	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.3525	NA	0.02435906
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	20q13.32	20	59173314	intergenic	ZNF831	NA	NA	ENSG00000124203	NA	NA	rs259981-A	rs259981	0	259981	intron_variant	FALSE	0.3597	1e-9	9	NA	0.02282645	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.3597	NA	0.02282645
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	NA	NA	NA	HELZ2	NA	NA	NA	NA	NA	NA	chr20:62196253-A	chr20:62196253	0	NA	NA	TRUE	0.412	8e-10	9.096910013008056	NA	0.02219634	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.412	NA	0.02219634
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	22q11.21	22	21563190	UBE2L3	UBE2L3	NA	NA	ENSG00000185651	NA	NA	rs5998509-T	rs5998509	0	5998509	intron_variant	FALSE	0.1887	3e-14	13.522878745280337	NA	0.0345522	[0.026-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.1887	NA	0.0345522
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	22q12.2	22	30153082	HORMAD2	HORMAD2	NA	NA	ENSG00000176635	NA	NA	rs5763821-C	rs5763821	0	5763821	intron_variant	FALSE	0.4399	1e-13	13	NA	0.02654227	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4399	NA	0.02654227
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	22q13.2	22	41381237	TEF	TEF	NA	NA	ENSG00000167074	NA	NA	rs2234052-G	rs2234052	0	2234052	intron_variant	FALSE	0.2241	2e-9	8.698970004336019	NA	0.02548559	[0.017-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.2241	NA	0.02548559
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	5q32	5	148820448	intergenic	HTR4 - ADRB2	ENSG00000164270	ENSG00000169252	NA	143213	6163	rs56330463-C	rs56330463	0	56330463	regulatory_region_variant	TRUE	0.5508	3e-27	26.522878745280337	NA	0.03942365	[0.032-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.5508	NA	0.03942365
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6p22.1	6	29955646	HLA-W	HLA-A - HLA-W	ENSG00000235657	ENSG00000235144	NA	9762	950	rs9260639-T	rs9260639	0	9260639	intron_variant	TRUE	0.1389	2e-14	13.698970004336019	NA	0.03938988	[0.029-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1389	NA	0.03938988
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6p21.1	6	42548053	intergenic	TRERF1 - UBR2	ENSG00000124496	ENSG00000024048	NA	96002	15976	rs16895831-T	rs16895831	0	16895831	regulatory_region_variant	TRUE	0.2033	2e-10	9.698970004336019	NA	0.02848855	[0.02-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2033	NA	0.02848855
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6q21	6	107810094	SCML4	SCML4	NA	NA	ENSG00000146285	NA	NA	rs11966931-A	rs11966931	0	11966931	intron_variant	FALSE	0.2384	4e-9	8.397940008672037	NA	0.02490724	[0.017-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2384	NA	0.02490724
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	17q21.1	17	40017384	CSF3	CSF3	NA	NA	ENSG00000108342	NA	NA	rs146890554-T	rs146890554	0	146890554	3_prime_UTR_variant	FALSE	0.0135	1e-13	13	NA	0.1166919	[0.086-0.148] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0135	NA	0.1166919
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	17q22	17	58309247	BZRAP1	TSPOAP1	NA	NA	ENSG00000005379	NA	NA	rs200436316-GTCCTCCTCT	rs200436316	0	200436316	inframe_insertion	FALSE	0.0534	3e-12	11.522878745280337	NA	0.05936271	[0.043-0.076] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0534	NA	0.05936271
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	19p13.3	19	1079960	HMHA1	ARHGAP45	NA	NA	ENSG00000180448	NA	NA	rs36084354-A	rs36084354	0	36084354	missense_variant	FALSE	0.092	2e-12	11.698970004336019	NA	0.04331237	[0.031-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.092	NA	0.04331237
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	19p13.13	19	13114672	TRMT1	TRMT1	NA	NA	ENSG00000104907	NA	NA	rs12977417-A	rs12977417	0	12977417	intron_variant	FALSE	0.1769	4e-9	8.397940008672037	NA	0.02883879	[0.019-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1769	NA	0.02883879
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	19q13.31	19	43648948	PLAUR	PLAUR	NA	NA	ENSG00000011422	NA	NA	rs4760-G	rs4760	0	4760	missense_variant	FALSE	0.157	2e-33	32.69897000433602	NA	0.0591609	[0.05-0.069] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.157	NA	0.0591609
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	20q13.12	20	44413724	HNF4A	HNF4A	NA	NA	ENSG00000101076	NA	NA	rs1800961-T	rs1800961	0	1800961	missense_variant	FALSE	0.0313	1e-10	10	NA	0.06643613	[0.046-0.087] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0313	NA	0.06643613
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1p36.11	1	26692640	RP5-968P14.2	RNU7-29P - ARID1A	ENSG00000252429	ENSG00000117713	NA	90208	596	rs112203773-A	rs112203773	0	112203773	non_coding_transcript_exon_variant	TRUE	0.0829	4e-9	8.397940008672037	NA	0.0381765	[0.025-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0829	NA	0.0381765
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1p34.3	1	36478315	CSF3R	CSF3R	NA	NA	ENSG00000119535	NA	NA	rs3917932-G	rs3917932	0	3917932	intron_variant	FALSE	0.5759	1e-23	23	NA	0.03620792	[0.029-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.5759	NA	0.03620792
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	NA	NA	NA	CSF3R	NA	NA	NA	NA	NA	NA	chr1:36952851-A	chr1:36952851	0	NA	NA	TRUE	0.0111	1e-14	14	NA	0.1327145	[0.099-0.166] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0111	NA	0.1327145
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1p32.2	1	56440602	intergenic	LINC01767 - PLPP3	ENSG00000223956	ENSG00000162407	NA	23465	54159	rs7537229-A	rs7537229	0	7537229	intron_variant	TRUE	0.8958	3e-24	23.522878745280337	NA	0.05930679	[0.048-0.071] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.8958	NA	0.05930679
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1p31.3	1	65671509	intergenic	LEPR - RN7SL854P	ENSG00000116678	ENSG00000239319	NA	29950	89549	rs34293785-C	rs34293785	0	34293785	intergenic_variant	TRUE	0.3664	1e-13	13	NA	0.0276318	[0.02-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3664	NA	0.0276318
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1p31.3	1	67023487	SLC35D1	SLC35D1	NA	NA	ENSG00000116704	NA	NA	rs145445141-A	rs145445141	1	35716426	intron_variant	FALSE	0.7896	7e-11	10.154901959985743	NA	0.02867173	[0.02-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.7896	NA	0.02867173
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1p22.1	1	92300881	RPAP2	RPAP2	NA	NA	ENSG00000122484	NA	NA	rs115340020-A	rs115340020	0	115340020	intron_variant	FALSE	0.0286	2e-11	10.698970004336019	NA	0.07137411	[0.05-0.092] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0286	NA	0.07137411
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	4p14	4	38362516	RP11-83C7.1	TBC1D1 - LINC02513	ENSG00000065882	ENSG00000248227	NA	223341	4398	rs33942080-G	rs33942080	0	33942080	intergenic_variant	TRUE	0.6811	7e-29	28.154901959985743	NA	0.04276293	[0.035-0.05] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.6811	NA	0.04276293
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	4q12	4	54530155	intergenic	LINC02283 - LINC02260	ENSG00000248184	ENSG00000250456	NA	174201	73056	rs218243-G	rs218243	0	218243	intergenic_variant	TRUE	0.1874	1e-10	10	NA	0.02985492	[0.021-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1874	NA	0.02985492
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	4q13.3	4	73835795	CXCL6	CXCL8 - CXCL6	ENSG00000169429	ENSG00000124875	NA	92079	845	rs62312418-A	rs62312418	0	62312418	intergenic_variant	TRUE	0.4049	5e-32	31.30102999566398	NA	0.04315252	[0.036-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.4049	NA	0.04315252
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	4q13.3	4	74094279	CXCL2	PPBPP2 - CXCL2	ENSG00000248848	ENSG00000081041	NA	38880	2761	rs11725704-G	rs11725704	0	11725704	regulatory_region_variant	TRUE	0.3762	3e-48	47.52287874528034	NA	0.05377511	[0.047-0.061] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3762	NA	0.05377511
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	4q21.21	4	79958649	ANTXR2	ANTXR2	NA	NA	ENSG00000163297	NA	NA	rs7655441-T	rs7655441	0	7655441	intron_variant	FALSE	0.7408	7e-12	11.154901959985743	NA	0.02751349	[0.02-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.7408	NA	0.02751349
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	4q21.22	4	82886057	SEC31A	SEC31A	NA	NA	ENSG00000138674	NA	NA	rs57960857-A	rs57960857	0	57960857	intron_variant	FALSE	0.5978	8e-9	8.096910013008056	NA	0.02111551	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.5978	NA	0.02111551
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	4q24	4	102570706	NFKB1	NFKB1	NA	NA	ENSG00000109320	NA	NA	rs230501-C	rs230501	0	230501	intron_variant	FALSE	0.6347	1e-14	14	NA	0.02852236	[0.021-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.6347	NA	0.02852236
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	4q24	4	105204229	TET2	TET2	NA	NA	ENSG00000168769	NA	NA	rs546941547-A	rs546941547	0	546941547	intron_variant	FALSE	0.4614	1e-20	20	NA	0.0334381	[0.026-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.4614	NA	0.0334381
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	5p15.33	5	1280013	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs7734992-C	rs7734992	0	7734992	intron_variant	FALSE	0.422	3e-11	10.522878745280337	NA	0.02457254	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.422	NA	0.02457254
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	5p13.2	5	35852868	IL7R	IL7R	NA	NA	ENSG00000168685	NA	NA	rs151286246-C	rs151286246	0	151286246	5_prime_UTR_variant	FALSE	0.2592	2e-19	18.69897000433602	NA	0.03670038	[0.029-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2592	NA	0.03670038
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	5q13.2	5	69294573	CCDC125	CCDC125, CCDC125	NA	NA	ENSG00000277868, ENSG00000183323	NA	NA	rs11741826-C	rs11741826	0	11741826	intron_variant	FALSE	0.4441	1e-9	9	NA	0.02199452	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.4441	NA	0.02199452
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	5q31.1	5	132619905	RAD50	RAD50	NA	NA	ENSG00000113522	NA	NA	rs10479009-G	rs10479009	0	10479009	intron_variant	FALSE	0.2097	2e-9	8.698970004336019	NA	0.02746763	[0.018-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2097	NA	0.02746763
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	5q35.3	5	177310719	MXD3	MXD3	NA	NA	ENSG00000213347	NA	NA	rs13190036-G	rs13190036	0	13190036	non_coding_transcript_exon_variant	FALSE	0.8923	1e-11	11	NA	0.03930816	[0.028-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.8923	NA	0.03930816
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	5q35.3	5	178694598	intergenic	CLK4 - MSANTD5	ENSG00000113240	ENSG00000285891	NA	63983	7	rs6866344-G	rs6866344	0	6866344	intergenic_variant	TRUE	0.2715	6e-10	9.221848749616356	NA	0.02471816	[0.017-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2715	NA	0.02471816
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6p22.3	6	24819824	FAM65B	RIPOR2	NA	NA	ENSG00000111913	NA	NA	rs6911302-C	rs6911302	0	6911302	intron_variant	FALSE	0.5516	2e-16	15.698970004336019	NA	0.02954939	[0.022-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.5516	NA	0.02954939
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6p21.33	6	31344282	intergenic	LINC02571 - HLA-B	ENSG00000256166	ENSG00000206450	NA	42640	9590	rs2256752-C	rs2256752	0	2256752	intron_variant	TRUE	0.3515	2e-13	12.698970004336019	NA	0.02753249	[0.02-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3515	NA	0.02753249
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6p21.33	6	31373994	FGFR3P1	RNU6-283P - FGFR3P1	ENSG00000201658	ENSG00000230994	NA	3754	3425	rs2523517-A	rs2523517	0	2523517	intron_variant	TRUE	0.3597	3e-17	16.522878745280337	NA	0.0314362	[0.024-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3597	NA	0.0314362
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6p21.32	6	32628763	HLA-DQA1	HLA-DQA1, HLA-DQA1	NA	NA	ENSG00000206305, ENSG00000196735	NA	NA	rs9271925-G	rs9271925	0	9271925	intron_variant	FALSE	0.3014	3e-9	8.522878745280337	NA	0.0266219	[0.018-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3014	NA	0.0266219
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6q14.1	6	81753659	FAM46A	TENT5A - SNORA70	ENSG00000112773	ENSG00000206886	NA	885	10365	rs915125-T	rs915125	0	915125	regulatory_region_variant	TRUE	0.2812	3e-9	8.522878745280337	NA	0.02370401	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2812	NA	0.02370401
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6q14.3	6	87280908	GJB7	ZNF292 - GJB7	ENSG00000188994	ENSG00000164411	NA	14965	2072	rs545836323-G	rs545836323	1	35051966	intergenic_variant	TRUE	0.4904	2e-18	17.69897000433602	NA	0.03127891	[0.024-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.4904	NA	0.03127891
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6q21	6	109268801	C6orf183	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs9487023-G	rs9487023	0	9487023	intron_variant	FALSE	0.4456	1e-13	13	NA	0.02658125	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.4456	NA	0.02658125
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	6q24.2	6	144064640	PLAGL1	PLAGL1 - SF3B5	ENSG00000118495	ENSG00000169976	NA	41	30244	rs149110519-T	rs149110519	0	149110519	TF_binding_site_variant	TRUE	0.0349	5e-17	16.30102999566398	NA	0.08266498	[0.063-0.102] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0349	NA	0.08266498
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	7p22.1	7	6458426	KDELR2, DAGLB	DAGLB, KDELR2	NA	NA	ENSG00000164535, ENSG00000136240	NA	NA	rs62454712-C	rs62454712	0	62454712	intron_variant	FALSE	0.2426	7e-25	24.154901959985743	NA	0.0432763	[0.035-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2426	NA	0.0432763
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	7p15.1	7	28237488	JAZF1-AS1	JAZF1-AS1	NA	NA	ENSG00000234336	NA	NA	rs2158799-G	rs2158799	0	2158799	intron_variant	FALSE	0.6082	1e-34	34	NA	0.04525739	[0.038-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.6082	NA	0.04525739
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	7p15.1	7	28684757	CREB5	CREB5	NA	NA	ENSG00000146592	NA	NA	rs56388170-T	rs56388170	0	56388170	intron_variant	FALSE	0.2957	3e-54	53.52287874528034	NA	0.06154059	[0.054-0.069] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2957	NA	0.06154059
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1p21.2	1	100773738	intergenic	VCAM1 - EXTL2	ENSG00000162692	ENSG00000162694	NA	34693	98634	rs147120681-C	rs147120681	0	147120681	regulatory_region_variant	TRUE	0.4365	4e-14	13.397940008672037	NA	0.0272701	[0.02-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.4365	NA	0.0272701
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1q21.3	1	150678699	GOLPH3L	GOLPH3L	NA	NA	ENSG00000143457	NA	NA	rs11800059-T	rs11800059	0	11800059	intron_variant	FALSE	0.5146	9e-19	18.045757490560675	NA	0.03155783	[0.025-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.5146	NA	0.03155783
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1q23.1	1	158615440	SPTA1	SPTA1	NA	NA	ENSG00000163554	NA	NA	rs2518491-T	rs2518491	0	2518491	intron_variant	FALSE	0.2659	4e-11	10.397940008672037	NA	0.02651297	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2659	NA	0.02651297
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1q23.2	1	159204893	DARC	CADM3-AS1, ACKR1	NA	NA	ENSG00000225670, ENSG00000213088	NA	NA	rs2814778-C	rs2814778	0	2814778	5_prime_UTR_variant	FALSE	0.0019	2e-11	10.698970004336019	NA	0.2783955	[0.2-0.36] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0019	NA	0.2783955
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1q23.2	1	159205704	DARC	ACKR1, CADM3-AS1	NA	NA	ENSG00000213088, ENSG00000225670	NA	NA	rs34599082-T	rs34599082	0	34599082	missense_variant	FALSE	0.0138	1e-18	18	NA	0.1346594	[0.1-0.16] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0138	NA	0.1346594
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1q42.13	1	226987666	RP5-1087E8.3	COQ8A - CDC42BPA	ENSG00000163050	ENSG00000143776	NA	122	2199	rs6426558-T	rs6426558	0	6426558	regulatory_region_variant	TRUE	0.5111	3e-14	13.522878745280337	NA	0.02704981	[0.02-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.5111	NA	0.02704981
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	1q44	1	247438293	NLRP3	NLRP3	NA	NA	ENSG00000162711	NA	NA	rs12239046-C	rs12239046	0	12239046	intron_variant	FALSE	0.6281	2e-9	8.698970004336019	NA	0.02202123	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.6281	NA	0.02202123
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2p23.3	2	25279683	DNMT3A	DNMT3A	NA	NA	ENSG00000119772	NA	NA	rs2006788-G	rs2006788	0	2006788	intron_variant	FALSE	0.3077	8e-10	9.096910013008056	NA	0.02384621	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3077	NA	0.02384621
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2p21	2	43224818	ZFP36L2	ZFP36L2	NA	NA	ENSG00000152518	NA	NA	rs149290349-A	rs149290349	0	149290349	missense_variant	FALSE	0.0761	2e-36	35.69897000433602	NA	0.08704756	[0.074-0.101] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0761	NA	0.08704756
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2q13	2	110869157	ACOXL	ACOXL	NA	NA	ENSG00000153093	NA	NA	rs2341873-C	rs2341873	0	2341873	intron_variant	FALSE	0.7	2e-9	8.698970004336019	NA	0.02349403	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.7	NA	0.02349403
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2q13	2	111033227	ACOXL	MIR4435-2HG, ACOXL	NA	NA	ENSG00000172965, ENSG00000153093	NA	NA	rs3789088-C	rs3789088	0	3789088	intron_variant	FALSE	0.1655	2e-11	10.698970004336019	NA	0.03199461	[0.023-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1655	NA	0.03199461
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2q13	2	111165510	BCL2L11	MIR4435-2HG, BCL2L11	NA	NA	ENSG00000172965, ENSG00000153094	NA	NA	rs68021656-GT	rs68021656	0	68021656	3_prime_UTR_variant	FALSE	0.1025	3e-10	9.522878745280337	NA	0.03725625	[0.026-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1025	NA	0.03725625
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2q13	2	111473966	MIR4435-1HG	MIR4435-2HG	NA	NA	ENSG00000172965	NA	NA	rs11695997-A	rs11695997	0	11695997	intron_variant	FALSE	0.0798	5e-10	9.301029995663981	NA	0.04487325	[0.031-0.059] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0798	NA	0.04487325
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2q14.1	2	113108257	IL1RN	IL1RN	NA	NA	ENSG00000136689	NA	NA	rs10171849-C	rs10171849	0	10171849	intron_variant	FALSE	0.3877	5e-11	10.301029995663981	NA	0.02408378	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3877	NA	0.02408378
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2q24.2	2	159661779	intergenic	BAZ2B - RPS3AP13	ENSG00000123636	ENSG00000230783	NA	45210	27438	rs34435647-C	rs34435647	0	34435647	intergenic_variant	TRUE	0.3783	1e-10	10	NA	0.02368909	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3783	NA	0.02368909
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2q31.3	2	181155969	AC104820.2	LINC01934	NA	NA	ENSG00000234663	NA	NA	rs59395276-C	rs59395276	0	59395276	intron_variant	FALSE	0.3209	2e-11	10.698970004336019	NA	0.02567474	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3209	NA	0.02567474
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2q33.1	2	201288355	ALS2CR12	FLACC1	NA	NA	ENSG00000155749	NA	NA	rs1035142-G	rs1035142	0	1035142	3_prime_UTR_variant	FALSE	0.6394	7e-12	11.154901959985743	NA	0.02538182	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.6394	NA	0.02538182
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2q35	2	218135259	CXCR2	CXCR2	NA	NA	ENSG00000180871	NA	NA	rs55799208-A	rs55799208	0	55799208	missense_variant	FALSE	0.0029	3e-25	24.522878745280337	NA	0.3710271	[0.3-0.44] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0029	NA	0.3710271
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	2q35	2	218156235	intergenic	CXCR2 - CXCR1	ENSG00000180871	ENSG00000163464	NA	18984	6606	rs114050631-T	rs114050631	0	114050631	regulatory_region_variant	TRUE	0.0106	8e-13	12.096910013008056	NA	0.1385776	[0.1-0.18] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0106	NA	0.1385776
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	3p25.2	3	12247950	intergenic	SYN2 - GSTM5P1	ENSG00000157152	ENSG00000236062	NA	55918	9851	rs9310400-T	rs9310400	0	9310400	intergenic_variant	TRUE	0.3285	1e-12	12	NA	0.02715901	[0.02-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3285	NA	0.02715901
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	3p21.31	3	47207586	KIF9-AS1	KIF9-AS1	NA	NA	ENSG00000227398	NA	NA	rs57383920-TA	rs57383920	0	57383920	intron_variant	FALSE	0.1905	1e-17	17	NA	0.03898093	[0.03-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1905	NA	0.03898093
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	3p13	3	71332916	FOXP1	FOXP1	NA	NA	ENSG00000114861	NA	NA	rs71298382-G	rs71298382	0	71298382	5_prime_UTR_variant	FALSE	0.0286	8e-11	10.096910013008056	NA	0.07561602	[0.053-0.098] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0286	NA	0.07561602
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	3q21.3	3	128479261	GATA2	DNAJB8-AS1 - GATA2	ENSG00000242049	ENSG00000179348	NA	6944	166	rs2713579-A	rs2713579	0	2713579	intergenic_variant	TRUE	0.6548	2e-11	10.698970004336019	NA	0.02554502	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.6548	NA	0.02554502
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	3q21.3	3	128597592	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	21506	22377	rs4328821-G	rs4328821	0	4328821	intergenic_variant	TRUE	0.1077	5e-50	49.30102999566398	NA	0.08527041	[0.074-0.097] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1077	NA	0.08527041
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	4p14	4	38124190	TBC1D1	TBC1D1	NA	NA	ENSG00000065882	NA	NA	rs636487-C	rs636487	0	636487	intron_variant	FALSE	0.3403	5e-9	8.301029995663981	NA	0.02203569	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.3403	NA	0.02203569
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	18q12.3	18	45782716	SLC14A1	SLC14A1 - SIGLEC15	ENSG00000141469	ENSG00000197046	NA	30196	42959	rs16978499-C	rs16978499	0	16978499	regulatory_region_variant	TRUE	0.001946	3e-6	5.522878745280337	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.001946	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	19p13.2	19	9807553	FBXL12	ZNF846 - FBXL12	ENSG00000196605	ENSG00000127452	NA	14373	2714	rs7246760-A	rs7246760	0	7246760	regulatory_region_variant	TRUE	0.06349	5e-6	5.301029995663981	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.06349	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	21q11.2	21	14743715	LOC388813	SAMSN1 - POLR2CP1	ENSG00000155307	ENSG00000228600	NA	84894	13873	rs9636593-G	rs9636593	0	9636593	intron_variant	TRUE	0.3268	3e-6	5.522878745280337	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.3268	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	7q31.33	7	125615031	LOC101928283	NA	NA	NA	NA	NA	NA	rs201048567-?	rs201048567	0	201048567	intergenic_variant	TRUE	NR	6e-9	8.221848749616356	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	STAMBP	NA	NA	NA	NA	NA	NA	chr2:74086046:I-AC	chr2:74086046:I	0	NA	NA	TRUE	0.1144	1e-6	6	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.1144	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	DIP2A	NA	NA	NA	NA	NA	NA	exm2268377-A	exm2268377	0	NA	NA	TRUE	0.4665	3e-6	5.522878745280337	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.4665	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	8q24.3	8	143933366	PLEC	PLEC	NA	NA	ENSG00000178209	NA	NA	rs7003580-C	rs7003580	0	7003580	intron_variant	FALSE	0.4097	4e-6	5.3979400086720375	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.4097	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	22q12.1	22	26563860	TPST2	TPST2	NA	NA	ENSG00000128294	NA	NA	rs2283831-A	rs2283831	0	2283831	intron_variant	FALSE	0.2357	4e-6	5.3979400086720375	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.2357	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	5p13.3	5	29090677	LOC101929645	LINC02109	NA	NA	ENSG00000259786	NA	NA	rs173684-A	rs173684	0	173684	intron_variant	FALSE	0.4885	5e-6	5.301029995663981	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.4885	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	8p11.21	8	41092754	SFRP1	RNU6-356P - LINC00968	ENSG00000206867	ENSG00000246430	NA	59756	15403294	rs16890285-G	rs16890285	0	16890285	regulatory_region_variant	TRUE	0.142	5e-6	5.301029995663981	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.142	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	21q11.2	21	14706751	LOC388813	SAMSN1 - POLR2CP1	ENSG00000155307	ENSG00000228600	NA	47930	50837	rs17004073-A	rs17004073	0	17004073	intron_variant	TRUE	0.1189	5e-6	5.301029995663981	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.1189	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	7q31.33	7	127150893	GRM8	GRM8	NA	NA	ENSG00000179603	NA	NA	rs17867775-T	rs17867775	0	17867775	intron_variant	FALSE	0.1187	6e-6	5.221848749616356	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.1187	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	8p23.2	8	4061891	CSMD1	CSMD1	NA	NA	ENSG00000183117	NA	NA	rs7015239-G	rs7015239	0	7015239	intron_variant	FALSE	0.229	6e-6	5.221848749616356	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.229	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	TMEM72-AS1	NA	NA	NA	NA	NA	NA	chr10:45162664:D-A	chr10:45162664:D	0	NA	NA	TRUE	0.1352	7e-6	5.154901959985743	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.1352	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	2p21	2	46505266	ATP6V1E2	ATP6V1E2	NA	NA	ENSG00000250565	NA	NA	rs11125080-G	rs11125080	0	11125080	intron_variant	FALSE	0.1689	8e-6	5.096910013008056	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.1689	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	3q29	3	193043928	MB21D2	NA	NA	NA	NA	NA	NA	rs2367278-G	rs2367278	0	2367278	intergenic_variant	TRUE	0.07584	9e-6	5.045757490560675	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.07584	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	15q21.3	15	54207566	UNC13C	UNC13C	NA	NA	ENSG00000137766	NA	NA	rs12591055-C	rs12591055	0	12591055	intron_variant	FALSE	0.1149	9e-6	5.045757490560675	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.1149	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	2q23.3	2	153322119	RPRM	NA - LINC01850	NA	ENSG00000227708	NA	NA	15586	rs72873391-A	rs72873391	0	72873391	intergenic_variant	TRUE	0.07305	9e-7	6.045757490560675	(EA)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.07305	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	21q21.1	21	20237054	LINC00320	NA - LINC02573	NA	ENSG00000233236	NA	NA	19698	rs141237305-G	rs141237305	1	12482578	intergenic_variant	TRUE	0.05	1e-6	6	(EA)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.05	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	1q42.2	1	231762845	TSNAX-DISC1	TSNAX-DISC1, DISC1	NA	NA	ENSG00000270106, ENSG00000162946	NA	NA	rs11122330-G	rs11122330	0	11122330	intron_variant	FALSE	0.1129	2e-6	5.698970004336019	(EA)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.1129	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	12q24.33	12	132216510	GALNT9	GALNT9	NA	NA	ENSG00000182870	NA	NA	rs11834862-A	rs11834862	0	11834862	intron_variant	FALSE	0.2065	2e-6	5.698970004336019	(EA)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.2065	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	19q13.2	19	38855269	HNRNPL	HNRNPL - RINL	ENSG00000104824	ENSG00000282895	NA	2922	12561	rs140569062-T	rs140569062	0	140569062	TF_binding_site_variant	TRUE	0.2922	2e-6	5.698970004336019	(EA)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.2922	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	3p24.1	3	30258824	RBMS3	NA - U3	NA	ENSG00000221673	NA	NA	45497	rs2888238-A	rs2888238	0	2888238	TF_binding_site_variant	TRUE	0.1794	5e-6	5.301029995663981	(EA)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.1794	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	12p13.32	12	4814531	KCNA6	GALNT8	NA	NA	ENSG00000130035	NA	NA	rs2058205-T	rs2058205	0	2058205	non_coding_transcript_exon_variant	FALSE	0.3072	7e-6	5.154901959985743	(EA)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.3072	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	14q32.31	14	101884215	PPP2R5C	PPP2R5C	NA	NA	ENSG00000078304	NA	NA	rs3783364-G	rs3783364	0	3783364	intron_variant	FALSE	0.04902	8e-6	5.096910013008056	(EA)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.04902	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	6q24.2	6	143994082	PLAGL1	PLAGL1	NA	NA	ENSG00000118495	NA	NA	rs6928827-A	rs6928827	0	6928827	intron_variant	FALSE	0.1263	9e-6	5.045757490560675	(EA)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.1263	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	10p11.22	10	32098880	KIF5B	Y_RNA - RPS4XP11	ENSG00000199964	ENSG00000234335	NA	42041	3642	rs117623576-T	rs117623576	0	117623576	intergenic_variant	TRUE	0.09032	9e-6	5.045757490560675	(EA)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.09032	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	21q11.2	21	14706751	LOC388813	SAMSN1 - POLR2CP1	ENSG00000155307	ENSG00000228600	NA	47930	50837	rs17004073-A	rs17004073	0	17004073	intron_variant	TRUE	0.07036	5e-7	6.301029995663981	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.07036	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	12q24.33	12	132218673	GALNT9	GALNT9	NA	NA	ENSG00000182870	NA	NA	rs7306456-G	rs7306456	0	7306456	intron_variant	FALSE	0.3776	6e-7	6.221848749616356	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.3776	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	SAP130	NA	NA	NA	NA	NA	NA	chr2:128781506:D-C	chr2:128781506:D	0	NA	NA	TRUE	0.2676	8e-7	6.096910013008056	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.2676	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	4p15.2	4	22938588	GBA3	NA	NA	NA	NA	NA	NA	rs16873221-T	rs16873221	0	16873221	intergenic_variant	TRUE	0.0607	2e-6	5.698970004336019	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.0607	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	STAMBP	NA	NA	NA	NA	NA	NA	chr2:74086046:I-AC	chr2:74086046:I	0	NA	NA	TRUE	0.04095	3e-6	5.522878745280337	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.04095	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	12q15	12	68096560	IFNG	IFNG-AS1	NA	NA	ENSG00000255733	NA	NA	rs10735946-C	rs10735946	0	10735946	intron_variant	FALSE	0.387	3e-6	5.522878745280337	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.387	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	13q14.2	13	47511391	LINC00562	RN7SL700P - NA	ENSG00000244521	NA	NA	52157	NA	rs17070253-C	rs17070253	0	17070253	intergenic_variant	TRUE	0.06034	3e-6	5.522878745280337	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.06034	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	ZZEF1	NA	NA	NA	NA	NA	NA	exm1279674-C	exm1279674	0	NA	NA	TRUE	0.009165	3e-6	5.522878745280337	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.009165	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	FAM71E2	NA	NA	NA	NA	NA	NA	exm1508736-T	exm1508736	0	NA	NA	TRUE	0.124	3e-6	5.522878745280337	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.124	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	20p12.3	20	5416598	LINC00658	RNA5-8SP7 - LINC00658	ENSG00000200313	ENSG00000226995	NA	70438	10294	rs1884752-G	rs1884752	0	1884752	intron_variant	TRUE	0.4714	3e-6	5.522878745280337	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.4714	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	22q12.1	22	26563860	TPST2	TPST2	NA	NA	ENSG00000128294	NA	NA	rs2283831-A	rs2283831	0	2283831	intron_variant	FALSE	0.2522	4e-6	5.3979400086720375	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.2522	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	7q36.3	7	156373855	LOC285889	ZNF655 - LINC01006	ENSG00000197343	ENSG00000182648	NA	56797402	15067	rs4716602-G	rs4716602	0	4716602	intergenic_variant	TRUE	0.3766	5e-6	5.301029995663981	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.3766	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	7q31.33	7	125604523	LOC101928283	NA	NA	NA	NA	NA	NA	rs73435943-T	rs73435943	0	73435943	intergenic_variant	TRUE	0.09349	8e-6	5.096910013008056	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.09349	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	13q12.13	13	27024689	USP12	RPS20P32 - USP12	ENSG00000218198	ENSG00000152484	NA	6780	41467	rs3123308-A	rs3123308	0	3123308	regulatory_region_variant	TRUE	0.4302	8e-6	5.096910013008056	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.4302	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	21q21.1	21	18743288	MIR548XHG	MIR548XHG	NA	NA	ENSG00000224141	NA	NA	rs59376436-G	rs59376436	0	59376436	intron_variant	FALSE	0.06237	8e-6	5.096910013008056	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.06237	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	8q24.3	8	139201287	COL22A1	NA	NA	NA	NA	NA	NA	rs7001362-G	rs7001362	0	7001362	intergenic_variant	TRUE	0.382	9e-6	5.045757490560675	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.382	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade response	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	9q22.2	9	90938770	SYK	SYK - NA	ENSG00000165025	NA	NA	40221	NA	rs291748-G	rs291748	0	291748	intergenic_variant	TRUE	0.142	9e-6	5.045757490560675	NA	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005025	Genome-wide genotyping array	0.142	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	1p36.13	1	17669971	ARHGEF10L	ARHGEF10L	NA	NA	ENSG00000074964	NA	NA	rs146330533-?	rs146330533	0	146330533	intron_variant	FALSE	NR	3e-7	6.522878745280337	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	2q37.1	2	234306004	ARL4C	NA - RPS20P12	NA	ENSG00000237784	NA	NA	23479	rs13001243-?	rs13001243	0	13001243	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	18q11.2	18	23164290	CABLES1	CABLES1	NA	NA	ENSG00000134508	NA	NA	rs4800149-?	rs4800149	0	4800149	intron_variant	FALSE	NR	7e-8	7.154901959985743	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	14q23.1	14	59578879	CCDC175	CCDC175 - RTN1	ENSG00000151838	ENSG00000139970	NA	2067	17097	rs34486957-?	rs34486957	0	34486957	intergenic_variant	TRUE	NR	4e-7	6.3979400086720375	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	12p11.21	12	30661250	IPO8	IPO8	NA	NA	ENSG00000133704	NA	NA	rs142754383-?	rs142754383	0	142754383	missense_variant	FALSE	NR	8e-12	11.096910013008056	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	12q21.33	12	90883555	LINC00615	LINC02822	NA	NA	ENSG00000286021	NA	NA	rs75062117-?	rs75062117	0	75062117	intron_variant	FALSE	NR	5e-7	6.301029995663981	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	2q24.1	2	155668568	LOC101929378	NA	NA	NA	NA	NA	NA	rs17305247-T	rs17305247	0	17305247	intergenic_variant	TRUE	0.01948	9e-6	5.045757490560675	(African)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.01948	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	6q12	6	66559283	SLC25A51P1	NA	NA	NA	NA	NA	NA	rs7753643-C	rs7753643	0	7753643	intergenic_variant	TRUE	0.08	9e-6	5.045757490560675	(African)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.08	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	7q31.31	7	118765854	ANKRD7	NA	NA	NA	NA	NA	NA	rs11763832-G	rs11763832	0	11763832	intergenic_variant	TRUE	0.03205	9e-6	5.045757490560675	(African)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.03205	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	17q25.1	17	73338334	SDK2	SDK2	NA	NA	ENSG00000069188	NA	NA	rs3195414-A	rs3195414	0	3195414	3_prime_UTR_variant	FALSE	0.1815	9e-6	5.045757490560675	(African)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.1815	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	18q22.3	18	73086404	LOC400655	NA - LINC02864	NA	ENSG00000263711	NA	NA	64837	rs80178925-A	rs80178925	0	80178925	intergenic_variant	TRUE	0.03333	9e-6	5.045757490560675	(African)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.03333	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	NGEF	NA	NA	NA	NA	NA	NA	PsychChip_15048346_B|psy_rs62193978-A	PsychChip_15048346_B|psy_rs62193978	0	NA	NA	TRUE	0.01362	5e-6	5.301029995663981	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.01362	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	2q37.3	2	240504237	ANKMY1	ANKMY1	NA	NA	ENSG00000144504	NA	NA	rs10933610-C	rs10933610	0	10933610	intron_variant	FALSE	0.1647	9e-6	5.045757490560675	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.1647	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	3q27.3	3	187601336	SST	NA - SST	NA	ENSG00000157005	NA	NA	67576	rs6788371-G	rs6788371	0	6788371	intergenic_variant	TRUE	0.372	4e-6	5.3979400086720375	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.372	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	LSG1	NA	NA	NA	NA	NA	NA	exm374029-A	exm374029	0	NA	NA	TRUE	0.0	5e-6	5.301029995663981	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	4q21.21	4	81394316	RASGEF1B	RNU5A-2P - RASGEF1B	ENSG00000207065	ENSG00000138670	NA	59898	32077	rs17005123-C	rs17005123	0	17005123	intergenic_variant	TRUE	0.01367	6e-7	6.221848749616356	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.01367	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	4q21.23	4	84031562	LOC101928978	NA	NA	NA	NA	NA	NA	rs1997474-T	rs1997474	0	1997474	intron_variant	TRUE	0.06	7e-6	5.154901959985743	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.06	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	6p24.3	6	8413179	SLC35B3	SLC35B3	NA	NA	ENSG00000124786	NA	NA	rs15300-G	rs15300	0	15300	3_prime_UTR_variant	FALSE	0.0336	2e-7	6.698970004336019	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.0336	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	6p24.3	6	8520673	LOC100506207	HULC	NA	NA	ENSG00000285219	NA	NA	rs113857308-T	rs113857308	0	113857308	intron_variant	FALSE	0.03226	5e-7	6.301029995663981	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.03226	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	6p22.3	6	17335171	RBM24	RBM24 - CAP2	ENSG00000112183	ENSG00000112186	NA	41300	58334	rs7776409-G	rs7776409	0	7776409	intergenic_variant	TRUE	0.0	1e-6	6	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	6q23.3	6	136547440	MAP7	MAP7	NA	NA	ENSG00000135525	NA	NA	rs9399186-T	rs9399186	0	9399186	intron_variant	FALSE	0.01383	8e-6	5.096910013008056	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.01383	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	LRGUK	NA	NA	NA	NA	NA	NA	exm658973-G	exm658973	0	NA	NA	TRUE	0.003891	4e-6	5.3979400086720375	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.003891	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	NSMCE2	NA	NA	NA	NA	NA	NA	chr8:126229601:I-ATT	chr8:126229601:I	0	NA	NA	TRUE	0.05556	3e-6	5.522878745280337	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.05556	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	9p24.1	9	8346473	PTPRD	PTPRD	NA	NA	ENSG00000153707	NA	NA	rs12340173-C	rs12340173	0	12340173	intron_variant	FALSE	0.01378	4e-7	6.3979400086720375	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.01378	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	9p22.2	9	17687751	SH3GL2	SH3GL2	NA	NA	ENSG00000107295	NA	NA	rs16935877-A	rs16935877	0	16935877	intron_variant	FALSE	0.07451	2e-7	6.698970004336019	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.07451	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	9q21.13	9	76222738	PCSK5	PCSK5	NA	NA	ENSG00000099139	NA	NA	rs62563392-A	rs62563392	0	62563392	intron_variant	FALSE	0.06612	3e-6	5.522878745280337	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.06612	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	10p15.1	10	5177576	AKR1C8P	AKR1C8P	NA	NA	ENSG00000264006	NA	NA	rs139515701-C	rs139515701	0	139515701	intron_variant	FALSE	0.1715	2e-7	6.698970004336019	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.1715	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	10p12.31	10	20458493	MIR4675	NA - MIR4675	NA	ENSG00000265372	NA	NA	93477	rs10828055-A	rs10828055	0	10828055	intergenic_variant	TRUE	0.3	9e-6	5.045757490560675	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.3	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	12q24.23	12	117921609	KSR2	KSR2	NA	NA	ENSG00000171435	NA	NA	rs61945387-G	rs61945387	0	61945387	intron_variant	FALSE	0.06276	3e-7	6.522878745280337	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.06276	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	NA	NA	NA	DDX19B	NA	NA	NA	NA	NA	NA	exm1253811-A	exm1253811	0	NA	NA	TRUE	0.0	5e-6	5.301029995663981	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Pursuit maintenance gain	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls	NA	18p11.32	18	843970	YES1	BOLA2P1 - ADCYAP1	ENSG00000266575	ENSG00000141433	NA	11501	60901	rs2846607-A	rs2846607	0	2846607	intergenic_variant	TRUE	0.1753	6e-6	5.221848749616356	(EA)	NA	NA	Illumina [4404269] (imputed)	N	pursuit maintenance gain measurement	http://www.ebi.ac.uk/efo/EFO_0008433	GCST005024	Genome-wide genotyping array	0.1753	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	13q22.2	13	75821206	LMO7	LMO7	NA	NA	ENSG00000136153	NA	NA	rs76082815-?	rs76082815	0	76082815	missense_variant	FALSE	NR	6e-9	8.221848749616356	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	1q32.2	1	208936211	LOC105372897	NA - LINC01774	NA	ENSG00000236950	NA	NA	36243	rs115777110-?	rs115777110	0	115777110	regulatory_region_variant	TRUE	NR	2e-8	7.698970004336019	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	7q36.3	7	156250946	LOC285889	Y_RNA - NA	ENSG00000199964	NA	NA	64723	NA	rs62482377-?	rs62482377	0	62482377	intergenic_variant	TRUE	NR	3e-7	6.522878745280337	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	21q21.3	21	28959613	LTN1	LTN1	NA	NA	ENSG00000198862	NA	NA	rs57646126-?	rs57646126	0	57646126	missense_variant	FALSE	NR	8e-8	7.096910013008056	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	4p16.1	4	11186225	MIR572	NA	NA	NA	NA	NA	NA	rs77867520-?	rs77867520	0	77867520	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	5q31.3	5	141945684	PCDH12	PCDH12	NA	NA	ENSG00000113555	NA	NA	rs105633-?	rs105633	0	105633	synonymous_variant	FALSE	NR	8e-12	11.096910013008056	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	20p12.2	20	9448697	PLCB4	PLCB4	NA	NA	ENSG00000101333	NA	NA	rs2299682-?	rs2299682	0	2299682	intron_variant	FALSE	NR	9e-8	7.045757490560675	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	20q11.23	20	37181711	RPN2	RPN2	NA	NA	ENSG00000118705	NA	NA	rs74417947-?	rs74417947	0	74417947	intron_variant	FALSE	NR	2e-8	7.698970004336019	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	2p22.1	2	39936810	SLC8A1-AS1	SLC8A1-AS1	NA	NA	ENSG00000227028	NA	NA	rs138449918-?	rs138449918	1	59919632	intron_variant	FALSE	NR	1e-7	7	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	12q24.33	12	130827204	STX2	STX2	NA	NA	ENSG00000111450	NA	NA	rs137928907-?	rs137928907	0	137928907	missense_variant	FALSE	NR	2e-8	7.698970004336019	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	12q13.13	12	53187599	ZNF740	ZNF740	NA	NA	ENSG00000139651	NA	NA	rs74796725-?	rs74796725	0	74796725	3_prime_UTR_variant	FALSE	NR	2e-8	7.698970004336019	(African)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	13q21.1	13	55819766	MIR5007	NA	NA	NA	NA	NA	NA	rs2997119-?	rs2997119	0	2997119	intergenic_variant	TRUE	NR	3e-7	6.522878745280337	(EA)	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	12p11.21	12	30661250	IPO8	IPO8	NA	NA	ENSG00000133704	NA	NA	rs142754383-?	rs142754383	0	142754383	missense_variant	FALSE	NR	9e-13	12.045757490560675	NA	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	13q22.2	13	75821206	LMO7	LMO7	NA	NA	ENSG00000136153	NA	NA	rs76082815-?	rs76082815	0	76082815	missense_variant	FALSE	NR	4e-8	7.3979400086720375	NA	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	6q12	6	65986379	SLC25A51P1	NA	NA	NA	NA	NA	NA	rs9354352-?	rs9354352	0	9354352	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	NA	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Initial pursuit acceleration in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases.	NA	6q12	6	65987110	SLC25A51P1	NA	NA	NA	NA	NA	NA	rs7766730-?	rs7766730	0	7766730	intergenic_variant	TRUE	NR	4e-7	6.3979400086720375	NA	NA	NA	Illumina [4404269] (imputed)	N	initial pursuit acceleration	http://www.ebi.ac.uk/efo/EFO_0008434	GCST005026	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade error rate in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases	NA	5p13.3	5	29091578	LOC101929645	LINC02109	NA	NA	ENSG00000259786	NA	NA	rs679895-?	rs679895	0	679895	intron_variant	FALSE	NR	2e-7	6.698970004336019	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005027	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade error rate in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases	NA	2p21	2	46505266	ATP6V1E2	ATP6V1E2	NA	NA	ENSG00000250565	NA	NA	rs11125080-?	rs11125080	0	11125080	intron_variant	FALSE	NR	2e-7	6.698970004336019	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005027	Genome-wide genotyping array	NA	NA	NA
2017-12-05	29064472	Lencer R	2017-10-24	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29064472	Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.	Anti-saccade error rate in psychotic disorders	114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases	NA	7q31.33	7	125615031	LOC101928283	NA	NA	NA	NA	NA	NA	rs201048567-?	rs201048567	0	201048567	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	(African)	NA	NA	Illumina [4404269] (imputed)	N	antisaccade response measurement	http://www.ebi.ac.uk/efo/EFO_0006874	GCST005027	Genome-wide genotyping array	NA	NA	NA
2017-11-13	19330027	Ahmed S	2009-05-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19330027	Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.	Breast cancer	390 European ancestry cases, 364 European ancestry controls	38,430 European ancestry cases, 2,572 East Asian ancestry cases, 41,926 European ancestry controls, 2,059 East Asian ancestry controls	3p24.1	3	27374522	SLC4A7, NEK10	SLC4A7	NA	NA	ENSG00000033867	NA	NA	rs4973768-T	rs4973768	0	4973768	3_prime_UTR_variant	FALSE	0.46	4e-23	22.397940008672037	NA	1.11	[1.08-1.13]	Illumina, Perlegen [up to 206586]	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004948	Genome-wide genotyping array	0.46	1.11	NA
2017-11-13	19330027	Ahmed S	2009-05-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19330027	Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.	Breast cancer	390 European ancestry cases, 364 European ancestry controls	38,430 European ancestry cases, 2,572 East Asian ancestry cases, 41,926 European ancestry controls, 2,059 East Asian ancestry controls	17q22	17	54979110	COX11	STXBP4	NA	NA	ENSG00000166263	NA	NA	rs6504950-G	rs6504950	0	6504950	intron_variant	FALSE	0.73	1e-8	8	NA	1.05	[1.03-1.09]	Illumina, Perlegen [up to 206586]	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004948	Genome-wide genotyping array	0.73	1.05	NA
2017-11-13	19330027	Ahmed S	2009-05-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19330027	Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.	Breast cancer	390 European ancestry cases, 364 European ancestry controls	11,645 European ancestry cases, 12,015 European ancestry controls	3p24.1	3	27145111	SLC4A7, NEK10	NEK10	NA	NA	ENSG00000163491	NA	NA	rs1357245-G	rs1357245	0	1357245	intron_variant	FALSE	0.54	2e-7	6.698970004336019	NA	1.06	NR	Perlegen [up to 206586]	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004949	Genome-wide genotyping array	0.54	1.06	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	17q12	17	37742390	HNF1B	HNF1B, HNF1B	NA	NA	ENSG00000276194, ENSG00000275410	NA	NA	rs11651052-A	rs11651052	0	11651052	intron_variant	FALSE	NR	3e-9	8.522878745280337	(female)	1.13	[1.09-1.18]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.13	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3p25.2	3	12295008	PPARG	PPARG	NA	NA	ENSG00000132170	NA	NA	rs11709077-G	rs11709077	0	11709077	intron_variant	FALSE	NR	1e-8	8	(female)	1.14	[1.09-1.20]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.14	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	7p15.1	7	28156794	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs849135-G	rs849135	0	849135	intron_variant	FALSE	NR	2e-8	7.698970004336019	(female)	1.1	[1.06-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.1	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	19q13.32	19	45655255	GIPR	RN7SL836P - GIPR	ENSG00000241226	ENSG00000010310	NA	3450	12966	rs8108269-G	rs8108269	0	8108269	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	(female)	1.1	[1.06-1.14]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.1	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3p14.1	3	64713769	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs4611812-C	rs4611812	0	4611812	intron_variant	FALSE	NR	3e-7	6.522878745280337	(female)	1.09	[1.05-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	4p16.1	4	6301295	WFS1	WFS1	NA	NA	ENSG00000109501	NA	NA	rs1801214-T	rs1801214	0	1801214	missense_variant	FALSE	NR	5e-7	6.301029995663981	(female)	1.09	[1.05-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	10q22.3	10	79182874	ZMIZ1	ZMIZ1	NA	NA	ENSG00000108175	NA	NA	rs12571751-A	rs12571751	0	12571751	intron_variant	FALSE	NR	1e-6	6	(female)	1.08	[1.05-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	7q32.2	7	130757382	KLF14	KLF14 - H4P1	ENSG00000266265	ENSG00000240680	NA	23175	65823	rs6467314-G	rs6467314	0	6467314	regulatory_region_variant	TRUE	NR	2e-6	5.698970004336019	(female)	1.09	[1.05-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	1q32.3	1	213981376	PROX1	PROX1-AS1	NA	NA	ENSG00000230461	NA	NA	rs2075423-G	rs2075423	0	2075423	non_coding_transcript_exon_variant	FALSE	0.622753026853543	8e-9	8.096910013008056	NA	1.07	[1.05-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.622753026853543	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2p23.3	2	27518370	GCKR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs780094-C	rs780094	0	780094	intron_variant	FALSE	0.613751766081311	5e-7	6.301029995663981	NA	1.06	[1.04-1.09]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.613751766081311	1.06	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2p21	2	43462891	THADA	THADA	NA	NA	ENSG00000115970	NA	NA	rs10203174-C	rs10203174	0	10203174	intron_variant	FALSE	0.893890367325954	1e-11	11	NA	1.14	[1.10-1.19]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.893890367325954	1.14	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2p16.1	2	60341610	BCL11A	MIR4432HG	NA	NA	ENSG00000228590	NA	NA	rs243088-T	rs243088	0	243088	non_coding_transcript_exon_variant	FALSE	0.44676300149567	2e-8	7.698970004336019	NA	1.07	[1.04-1.09]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.44676300149567	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2q24.2	2	160314943	RBMS1	RBMS1	NA	NA	ENSG00000153250	NA	NA	rs7593730-C	rs7593730	0	7593730	intron_variant	FALSE	NR	2e-6	5.698970004336019	NA	1.11	[1.06-1.15]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2q24.3	2	164672366	GRB14	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs13389219-C	rs13389219	0	13389219	intron_variant	FALSE	0.600895198408045	1e-8	8	NA	1.07	[1.05-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.600895198408045	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2q36.3	2	226228869	IRS1	NA	NA	NA	NA	NA	NA	rs2943640-C	rs2943640	0	2943640	intergenic_variant	TRUE	0.634514929084023	3e-14	13.522878745280337	NA	1.1	[1.07-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.634514929084023	1.1	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3p25.2	3	12351626	PPARG	PPARG	NA	NA	ENSG00000132170	NA	NA	rs1801282-C	rs1801282	0	1801282	missense_variant	FALSE	0.85520337260229	1e-12	12	NA	1.13	[1.09-1.17]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.85520337260229	1.13	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3p24.3	3	23413299	UBE2E2	UBE2E2	NA	NA	ENSG00000182247	NA	NA	rs1496653-A	rs1496653	0	1496653	intron_variant	FALSE	0.750927055549185	4e-9	8.397940008672037	NA	1.09	[1.06-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.750927055549185	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3p14.1	3	64719689	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs6795735-C	rs6795735	0	6795735	intron_variant	FALSE	0.589987598823279	7e-11	10.154901959985743	NA	1.08	[1.06-1.11]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.589987598823279	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3q21.1	3	123363551	ADCY5	ADCY5	NA	NA	ENSG00000173175	NA	NA	rs11717195-T	rs11717195	0	11717195	intron_variant	FALSE	0.77150989868268	6e-14	13.221848749616356	NA	1.11	[1.08-1.14]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.77150989868268	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3q27.2	3	185793899	IGF2BP2	IGF2BP2	NA	NA	ENSG00000073792	NA	NA	rs4402960-T	rs4402960	0	4402960	intron_variant	FALSE	0.32538541911922	2e-23	22.69897000433602	NA	1.13	[1.10-1.16]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.32538541911922	1.13	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	4p16.1	4	6288259	WFS1	WFS1	NA	NA	ENSG00000109501	NA	NA	rs4458523-G	rs4458523	0	4458523	intron_variant	FALSE	0.573657632191931	2e-15	14.698970004336019	NA	1.1	[1.07-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.573657632191931	1.1	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	5q11.2	5	56510924	ANKRD55	RPL26P19 - C5orf67	ENSG00000226221	ENSG00000225940	NA	5852	643	rs459193-G	rs459193	0	459193	intergenic_variant	TRUE	0.702406932963936	6e-9	8.221848749616356	NA	1.08	[1.05-1.11]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.702406932963936	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	5q13.3	5	77131486	ZBED3	ZBED3-AS1	NA	NA	ENSG00000250802	NA	NA	rs6878122-G	rs6878122	0	6878122	intron_variant	FALSE	0.2799582088267	5e-11	10.301029995663981	NA	1.1	[1.07-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.2799582088267	1.1	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	6p22.3	6	20679478	CDKAL1	CDKAL1	NA	NA	ENSG00000145996	NA	NA	rs7756992-G	rs7756992	0	7756992	intron_variant	FALSE	0.292255246133759	7e-35	34.15490195998574	NA	1.17	[1.14-1.20]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.292255246133759	1.17	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	7p21.2	7	14858657	DGKB	DGKB	NA	NA	ENSG00000136267	NA	NA	rs17168486-T	rs17168486	0	17168486	intron_variant	FALSE	0.19264055499943	6e-11	10.221848749616356	NA	1.11	[1.07-1.14]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.19264055499943	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	10q25.2	10	112998590	TCF7L2	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs7903146-T	rs7903146	0	7903146	intron_variant	FALSE	NR	6e-92	91.22184874961636	(men)	1.39	[1.35-1.44]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.39	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	16q12.2	16	53785257	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs9936385-C	rs9936385	0	9936385	intron_variant	FALSE	NR	3e-18	17.522878745280337	(men)	1.14	[1.11-1.17]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.14	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3q27.2	3	185795508	IGF2BP2	IGF2BP2	NA	NA	ENSG00000073792	NA	NA	rs7640539-A	rs7640539	0	7640539	intron_variant	FALSE	NR	2e-17	16.69897000433602	(men)	1.14	[1.11-1.18]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.14	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	8q24.11	8	117172786	SLC30A8	SLC30A8	NA	NA	ENSG00000164756	NA	NA	rs3802177-G	rs3802177	0	3802177	3_prime_UTR_variant	FALSE	NR	1e-16	16	(men)	1.15	[1.11-1.18]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.15	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	9p21.3	9	22133285	CDKN2A/B	CDKN2B-AS1 - DMRTA1	ENSG00000240498	ENSG00000176399	NA	5182	313539	rs10965250-G	rs10965250	0	10965250	intergenic_variant	TRUE	NR	9e-15	14.045757490560675	(men)	1.17	[1.13-1.22]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.17	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	NA	NA	NA	KCNQ1	NA	NA	NA	NA	NA	NA	rs163184-G	rs163184	0	163184	intron_variant	TRUE	NR	9e-15	14.045757490560675	(men)	1.12	[1.09-1.16]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.12	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	7p15.1	7	28156794	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs849135-G	rs849135	0	849135	intron_variant	FALSE	NR	3e-13	12.522878745280337	(men)	1.11	[1.08-1.15]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	7p21.2	7	14858657	DGKB	DGKB	NA	NA	ENSG00000136267	NA	NA	rs17168486-T	rs17168486	0	17168486	intron_variant	FALSE	NR	7e-13	12.154901959985743	(men)	1.15	[1.11-1.19]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.15	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	4p16.1	4	6301295	WFS1	WFS1	NA	NA	ENSG00000109501	NA	NA	rs1801214-T	rs1801214	0	1801214	missense_variant	FALSE	NR	3e-12	11.522878745280337	(men)	1.11	[1.08-1.15]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	10q23.33	10	92703125	HHEX, IDE	HHEX - Y_RNA	ENSG00000152804	ENSG00000199964	NA	7478	7374	rs1111875-C	rs1111875	0	1111875	intergenic_variant	TRUE	NR	5e-12	11.301029995663981	(men)	1.11	[1.07-1.14]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	8p11.21	8	41661730	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs516946-C	rs516946	0	516946	non_coding_transcript_exon_variant	FALSE	NR	8e-11	10.096910013008056	(men)	1.12	[1.08-1.16]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.12	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	5q13.3	5	77131486	ZBED3	ZBED3-AS1	NA	NA	ENSG00000250802	NA	NA	rs6878122-G	rs6878122	0	6878122	intron_variant	FALSE	NR	3e-10	9.522878745280337	(men)	1.12	[1.08-1.15]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.12	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	11q14.3	11	92975544	MTNR1B	MTNR1B	NA	NA	ENSG00000134640	NA	NA	rs10830963-G	rs10830963	0	10830963	intron_variant	FALSE	NR	3e-10	9.522878745280337	(men)	1.11	[1.07-1.14]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2p21	2	43478147	THADA	THADA	NA	NA	ENSG00000115970	NA	NA	rs13405158-T	rs13405158	0	13405158	intron_variant	FALSE	NR	5e-10	9.301029995663981	(men)	1.16	[1.11-1.22]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.16	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2p16.1	2	60341610	BCL11A	MIR4432HG	NA	NA	ENSG00000228590	NA	NA	rs243088-T	rs243088	0	243088	non_coding_transcript_exon_variant	FALSE	NR	7e-10	9.154901959985743	(men)	1.1	[1.06-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.1	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	12p13.32	12	4265207	CCND2	CCND2-AS1	NA	NA	ENSG00000255920	NA	NA	rs11063069-G	rs11063069	0	11063069	intron_variant	FALSE	NR	1e-9	9	(men)	1.12	[1.08-1.16]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.12	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	9q21.32	9	81694033	TLE1	TLE1 - RNU6-1035P	ENSG00000196781	ENSG00000207206	NA	4486	31210	rs2796441-G	rs2796441	0	2796441	intron_variant	TRUE	NR	5e-9	8.301029995663981	(men)	1.09	[1.06-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	11q13.4	11	72722053	ARAP1	ARAP1	NA	NA	ENSG00000186635	NA	NA	rs1552224-A	rs1552224	0	1552224	5_prime_UTR_variant	FALSE	NR	9e-9	8.045757490560675	(men)	1.12	[1.08-1.16]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.12	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2q36.3	2	226228869	IRS1	NA	NA	NA	NA	NA	NA	rs2943640-C	rs2943640	0	2943640	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	(men)	1.09	[1.06-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	12p11.22	12	27812217	KLHDC5	RN7SKP15 - PTHLH	ENSG00000201612	ENSG00000087494	NA	5827	145867	rs10842994-C	rs10842994	0	10842994	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	(men)	1.11	[1.07-1.15]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	18q21.32	18	60191596	MC4R	RNU4-17P - NA	ENSG00000202468	NA	NA	27889	NA	rs8089364-C	rs8089364	0	8089364	intergenic_variant	TRUE	NR	6e-8	7.221848749616356	(men)	1.09	[1.06-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	16q23.1	16	75213347	BCAR1	CTRB2 - CTRB1	ENSG00000284810	ENSG00000285346	NA	6186	5641	rs7202877-T	rs7202877	0	7202877	intergenic_variant	TRUE	NR	7e-8	7.154901959985743	(men)	1.15	[1.09-1.20]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.15	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	15q26.1	15	91000846	PRC1	VPS33B	NA	NA	ENSG00000184056	NA	NA	rs12899811-G	rs12899811	0	12899811	non_coding_transcript_exon_variant	FALSE	NR	8e-8	7.096910013008056	(men)	1.09	[1.05-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	12q14.3	12	65818538	HMGA2	RPSAP52	NA	NA	ENSG00000241749	NA	NA	rs2261181-T	rs2261181	0	2261181	intron_variant	FALSE	NR	1e-7	7	(men)	1.14	[1.09-1.19]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.14	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3p25.2	3	12295008	PPARG	PPARG	NA	NA	ENSG00000132170	NA	NA	rs11709077-G	rs11709077	0	11709077	intron_variant	FALSE	NR	2e-7	6.698970004336019	(men)	1.12	[1.07-1.17]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.12	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	19p13.11	19	19296909	CILP2	SUGP1	NA	NA	ENSG00000105705	NA	NA	rs10401969-C	rs10401969	0	10401969	intron_variant	FALSE	NR	3e-7	6.522878745280337	(men)	1.15	[1.09-1.21]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.15	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3q21.1	3	123346931	ADCY5	ADCY5	NA	NA	ENSG00000173175	NA	NA	rs11708067-A	rs11708067	0	11708067	intron_variant	FALSE	NR	4e-7	6.3979400086720375	(men)	1.09	[1.06-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3p24.3	3	23413299	UBE2E2	UBE2E2	NA	NA	ENSG00000182247	NA	NA	rs1496653-A	rs1496653	0	1496653	intron_variant	FALSE	NR	4e-7	6.3979400086720375	(men)	1.09	[1.05-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	9p24.2	9	4292083	GLIS3	GLIS3	NA	NA	ENSG00000107249	NA	NA	rs10758593-A	rs10758593	0	10758593	intron_variant	FALSE	NR	6e-7	6.221848749616356	(men)	1.08	[1.05-1.11]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	10q22.3	10	79182874	ZMIZ1	ZMIZ1	NA	NA	ENSG00000108175	NA	NA	rs12571751-A	rs12571751	0	12571751	intron_variant	FALSE	NR	6e-7	6.221848749616356	(men)	1.07	[1.04-1.11]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3p14.1	3	64713769	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs4611812-C	rs4611812	0	4611812	intron_variant	FALSE	NR	1e-6	6	(men)	1.08	[1.05-1.11]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	12q15	12	71045809	TSPAN8, LGR5	NA - TSPAN8	NA	ENSG00000127324	NA	NA	79276	rs7138300-C	rs7138300	0	7138300	intron_variant	TRUE	NR	2e-6	5.698970004336019	(men)	1.07	[1.04-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	15q24.3	15	77540420	HMG20A	HMG20A - LINGO1	ENSG00000140382	ENSG00000169783	NA	54813	72607	rs7177055-A	rs7177055	0	7177055	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(men)	1.08	[1.05-1.11]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	11p15.1	11	17396930	KCNJ11	ABCC8	NA	NA	ENSG00000006071	NA	NA	rs757110-C	rs757110	0	757110	missense_variant	FALSE	NR	3e-6	5.522878745280337	(men)	1.07	[1.04-1.11]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	9q21.31	9	79290675	TLE4	NA	NA	NA	NA	NA	NA	rs17791513-A	rs17791513	0	17791513	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(men)	1.14	[1.08-1.20]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.14	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	5q11.2	5	56510924	ANKRD55	RPL26P19 - C5orf67	ENSG00000226221	ENSG00000225940	NA	5852	643	rs459193-G	rs459193	0	459193	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(men)	1.08	[1.05-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	17q12	17	37742390	HNF1B	HNF1B, HNF1B	NA	NA	ENSG00000276194, ENSG00000275410	NA	NA	rs11651052-A	rs11651052	0	11651052	intron_variant	FALSE	NR	7e-6	5.154901959985743	(men)	1.09	[1.05-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	8q22.1	8	94925274	TP53INP1	NDUFAF6	NA	NA	ENSG00000156170	NA	NA	rs7845219-T	rs7845219	0	7845219	intron_variant	FALSE	NR	7e-6	5.154901959985743	(men)	1.07	[1.04-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	1q32.3	1	213981376	PROX1	PROX1-AS1	NA	NA	ENSG00000230461	NA	NA	rs2075423-G	rs2075423	0	2075423	non_coding_transcript_exon_variant	FALSE	NR	9e-6	5.045757490560675	(men)	1.07	[1.04-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	6p22.3	6	20679478	CDKAL1	CDKAL1	NA	NA	ENSG00000145996	NA	NA	rs7756992-G	rs7756992	0	7756992	intron_variant	FALSE	NR	2e-22	21.69897000433602	(men)	1.17	[1.35-1.44]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.17	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	10q25.2	10	112998590	TCF7L2	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs7903146-T	rs7903146	0	7903146	intron_variant	FALSE	NR	4e-73	72.39794000867204	(female)	1.39	[1.34-1.44]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.39	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	6p22.3	6	20679478	CDKAL1	CDKAL1	NA	NA	ENSG00000145996	NA	NA	rs7756992-G	rs7756992	0	7756992	intron_variant	FALSE	NR	2e-20	19.69897000433602	(female)	1.17	[1.14-1.22]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.17	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	9p21.3	9	22133285	CDKN2A/B	CDKN2B-AS1 - DMRTA1	ENSG00000240498	ENSG00000176399	NA	5182	313539	rs10965250-G	rs10965250	0	10965250	intergenic_variant	TRUE	NR	6e-16	15.221848749616356	(female)	1.2	[1.15-1.26]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.2	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	10q23.33	10	92703125	HHEX, IDE	HHEX - Y_RNA	ENSG00000152804	ENSG00000199964	NA	7478	7374	rs1111875-C	rs1111875	0	1111875	intergenic_variant	TRUE	NR	7e-13	12.154901959985743	(female)	1.12	[1.09-1.16]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.12	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	16q12.2	16	53785257	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs9936385-C	rs9936385	0	9936385	intron_variant	FALSE	NR	6e-11	10.221848749616356	(female)	1.12	[1.08-1.15]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.12	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	8q24.11	8	117172786	SLC30A8	SLC30A8	NA	NA	ENSG00000164756	NA	NA	rs3802177-G	rs3802177	0	3802177	3_prime_UTR_variant	FALSE	NR	7e-11	10.154901959985743	(female)	1.13	[1.09-1.17]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.13	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3q21.1	3	123346931	ADCY5	ADCY5	NA	NA	ENSG00000173175	NA	NA	rs11708067-A	rs11708067	0	11708067	intron_variant	FALSE	NR	2e-10	9.698970004336019	(female)	1.13	[1.09-1.18]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.13	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2q36.3	2	226228869	IRS1	NA	NA	NA	NA	NA	NA	rs2943640-C	rs2943640	0	2943640	intergenic_variant	TRUE	NR	1e-9	9	(female)	1.11	[1.07-1.14]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	3q27.2	3	185795508	IGF2BP2	IGF2BP2	NA	NA	ENSG00000073792	NA	NA	rs7640539-A	rs7640539	0	7640539	intron_variant	FALSE	NR	2e-9	8.698970004336019	(female)	1.11	[1.07-1.15]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	2q24.3	2	164645339	GRB14	GRB14 - COBLL1	ENSG00000115290	ENSG00000082438	NA	23857	8285	rs3923113-A	rs3923113	0	3923113	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	(female)	1.11	[1.08-1.15]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	NA	1.11	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	19q13.11	19	33829949	KCTD15	KCTD15 - RN7SL150P	ENSG00000153885	ENSG00000240626	NA	14186	97415	rs2546057-?	rs2546057	0	2546057	intergenic_variant	TRUE	NR	3e-10	9.522878745280337	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	19q13.32	19	45678134	GIPR	GIPR	NA	NA	ENSG00000010310	NA	NA	rs1800437-?	rs1800437	0	1800437	missense_variant	FALSE	NR	5e-9	8.301029995663981	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	19q13.32	19	47086638	ZC3H4	ZC3H4	NA	NA	ENSG00000130749	NA	NA	rs2303108-?	rs2303108	0	2303108	intron_variant	FALSE	NR	1e-9	9	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p34.1	1	46039475	PIK3R3	MAST2 - PIK3R3	ENSG00000086015	ENSG00000117461	NA	3353	665	rs1707322-?	rs1707322	0	1707322	regulatory_region_variant	TRUE	NR	7e-7	6.154901959985743	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	72371807	KRT8P21, NEGR1	RPL31P12 - NA	ENSG00000227207	NA	NA	69978	NA	rs11209951-?	rs11209951	0	11209951	intron_variant	TRUE	NR	6e-8	7.221848749616356	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	72478934	KRT8P21, NEGR1	NA	NA	NA	NA	NA	NA	rs7550173-?	rs7550173	0	7550173	intron_variant	TRUE	NR	2e-10	9.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p13.3	1	109540264	GPR61	GPR61	NA	NA	ENSG00000156097	NA	NA	rs7550711-?	rs7550711	0	7550711	intron_variant	FALSE	NR	6e-6	5.221848749616356	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.2	1	177920345	SEC16B	LINC01741 - SEC16B	ENSG00000236720	ENSG00000120341	NA	208070	3611	rs543874-?	rs543874	0	543874	intergenic_variant	TRUE	NR	5e-10	9.301029995663981	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p25.3	2	638144	TMEM18	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	91477	25733	rs4854344-?	rs4854344	0	4854344	regulatory_region_variant	TRUE	NR	9e-23	22.045757490560675	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p24.2	3	25075091	LOC100129045, RARB	RNA5SP125 - RARB	ENSG00000201713	ENSG00000077092	NA	49965	99241	rs4858697-?	rs4858697	0	4858697	intron_variant	TRUE	NR	4e-9	8.397940008672037	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p22.1	3	42273163	CCK	CCK - SALL4P6	ENSG00000187094	ENSG00000231280	NA	6978	47842	rs935111-?	rs935111	0	935111	intergenic_variant	TRUE	NR	6e-7	6.221848749616356	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p14.2	3	61250788	FHIT	FHIT	NA	NA	ENSG00000189283	NA	NA	rs2365389-?	rs2365389	0	2365389	intron_variant	FALSE	NR	5e-10	9.301029995663981	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p12.3	6	50898107	FTHP1, TFAP2B	RPS17P5 - FTH1P5	ENSG00000060303	ENSG00000230204	NA	40445	14605	rs943005-?	rs943005	0	943005	non_coding_transcript_exon_variant	TRUE	NR	4e-8	7.3979400086720375	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7q11.23	7	75533848	HIP1	HIP1	NA	NA	ENSG00000127946	NA	NA	rs1167827-?	rs1167827	0	1167827	3_prime_UTR_variant	FALSE	NR	2e-6	5.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9p21.1	9	28415514	LINGO2	LINGO2	NA	NA	ENSG00000174482	NA	NA	rs10968577-?	rs10968577	0	10968577	intron_variant	FALSE	NR	8e-8	7.096910013008056	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	10q25.2	10	112998590	TCF7L2	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs7903146-?	rs7903146	0	7903146	intron_variant	FALSE	NR	2e-7	6.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	11p14.1	11	27635242	BDNF	BDNF-AS	NA	NA	ENSG00000245573	NA	NA	rs4923460-?	rs4923460	0	4923460	intron_variant	FALSE	NR	7e-10	9.154901959985743	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	11p11.2	11	47508395	CUGBP1	CELF1	NA	NA	ENSG00000149187	NA	NA	rs7124681-?	rs7124681	0	7124681	intron_variant	FALSE	NR	7e-6	5.154901959985743	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	11p11.2	11	47629441	MTCH2	MTCH2	NA	NA	ENSG00000109919	NA	NA	rs3817334-?	rs3817334	0	3817334	intron_variant	FALSE	NR	1e-6	6	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q13.12	12	49853685	BCDIN3D, FAIM2	BCDIN3D - RPL35AP28	ENSG00000186666	ENSG00000242041	NA	10579	9488	rs7138803-?	rs7138803	0	7138803	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	16p13.3	16	3963466	ADCY9	ADCY9	NA	NA	ENSG00000162104	NA	NA	rs2531995-?	rs2531995	0	2531995	3_prime_UTR_variant	FALSE	NR	6e-6	5.221848749616356	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	16p12.3	16	19924067	GPRC5B	GPRC5B - NA	ENSG00000167191	NA	NA	37900	NA	rs12446632-?	rs12446632	0	12446632	intergenic_variant	TRUE	NR	5e-6	5.301029995663981	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	16p11.2	16	28814284	ATXN2L	NPIPB9 - ATXN2L	ENSG00000196993	ENSG00000168488	NA	41477	8715	rs2008514-?	rs2008514	0	2008514	non_coding_transcript_exon_variant	TRUE	NR	8e-10	9.096910013008056	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	16q12.2	16	53782363	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs8050136-?	rs8050136	0	8050136	intron_variant	FALSE	NR	4e-54	53.39794000867204	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	18q21.32	18	60172536	MC4R	RNU4-17P - NA	ENSG00000202468	NA	NA	8829	NA	rs571312-?	rs571312	0	571312	intergenic_variant	TRUE	NR	5e-24	23.30102999566398	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	72371807	KRT8P21, NEGR1	RPL31P12 - NA	ENSG00000227207	NA	NA	69978	NA	rs11209951-?	rs11209951	0	11209951	intron_variant	TRUE	NR	6e-10	9.221848749616356	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	74547370	TNNI3K	TNNI3K - ERICH3	ENSG00000116783	ENSG00000178965	NA	2942	20747	rs3843262-?	rs3843262	0	3843262	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q23	3	141587171	RASA2	RASA2	NA	NA	ENSG00000155903	NA	NA	rs2035935-?	rs2035935	0	2035935	intron_variant	FALSE	NR	6e-7	6.221848749616356	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q27.2	3	186096853	ETV5	ETV5	NA	NA	ENSG00000244405	NA	NA	rs6809651-?	rs6809651	0	6809651	intron_variant	FALSE	NR	9e-6	5.045757490560675	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4p12	4	45177866	GNPDA2	NA	NA	NA	NA	NA	NA	rs12641981-?	rs12641981	0	12641981	intergenic_variant	TRUE	NR	1e-12	12	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4q24	4	102267552	SLC39A8	SLC39A8	NA	NA	ENSG00000138821	NA	NA	rs13107325-?	rs13107325	0	13107325	missense_variant	FALSE	NR	2e-9	8.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q13.3	5	75738562	C5orf37, POC5	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078	NA	21114	14008	rs7715806-?	rs7715806	0	7715806	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q23.2	5	124994829	LOC644659, ZNF608	LINC02240	NA	NA	ENSG00000260192	NA	NA	rs6864049-?	rs6864049	0	6864049	intron_variant	FALSE	NR	2e-7	6.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	77582646	ZZZ3	ZZZ3	NA	NA	ENSG00000036549	NA	NA	rs17381664-?	rs17381664	0	17381664	intron_variant	FALSE	NR	4e-7	6.3979400086720375	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	77998184	DNAJB4	GIPC2, DNAJB4	NA	NA	ENSG00000137960, ENSG00000162616	NA	NA	rs4130548-?	rs4130548	0	4130548	intron_variant	FALSE	NR	1e-9	9	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	78212446	MGC27382	RNFT1P2 - MGC27382	ENSG00000233333	ENSG00000237413	NA	41209	17153	rs12406019-?	rs12406019	0	12406019	intergenic_variant	TRUE	NR	2e-10	9.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p13.3	1	109612066	GNAT2	GNAT2	NA	NA	ENSG00000134183	NA	NA	rs17024393-?	rs17024393	0	17024393	intron_variant	FALSE	NR	3e-9	8.522878745280337	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.2	1	177920345	SEC16B	LINC01741 - SEC16B	ENSG00000236720	ENSG00000120341	NA	208070	3611	rs543874-?	rs543874	0	543874	intergenic_variant	TRUE	NR	6e-29	28.221848749616356	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q31.1	1	190701754	LOC440704, RGS18	LINC01720	NA	NA	ENSG00000231175	NA	NA	rs1998710-?	rs1998710	0	1998710	intron_variant	FALSE	NR	1e-8	8	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p25.3	2	622827	TMEM18	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	76160	41050	rs2867125-?	rs2867125	0	2867125	intergenic_variant	TRUE	NR	7e-35	34.15490195998574	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p23.3	2	24927247	ADCY3	ADCY3 - DNAJC27	ENSG00000138031	ENSG00000115137	NA	7010	16389	rs6752378-?	rs6752378	0	6752378	intergenic_variant	TRUE	NR	2e-14	13.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p16.1	2	58461772	FLJ30838	LINC01122	NA	NA	ENSG00000233723	NA	NA	rs2075171-?	rs2075171	0	2075171	splice_region_variant	FALSE	NR	2e-8	7.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p16.1	2	59102018	LOC730134, FLJ30838	LINC01122 - NA	ENSG00000233723	NA	NA	38252	NA	rs759250-?	rs759250	0	759250	intron_variant	TRUE	NR	8e-9	8.096910013008056	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p14.2	3	61250788	FHIT	FHIT	NA	NA	ENSG00000189283	NA	NA	rs2365389-?	rs2365389	0	2365389	intron_variant	FALSE	NR	1e-6	6	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q22.3	3	138389241	MRAS	MRAS	NA	NA	ENSG00000158186	NA	NA	rs1720825-?	rs1720825	0	1720825	intron_variant	FALSE	NR	5e-6	5.301029995663981	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q23	3	141576936	RASA2	RASA2	NA	NA	ENSG00000155903	NA	NA	rs3732869-?	rs3732869	0	3732869	intron_variant	FALSE	NR	8e-6	5.096910013008056	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q27.2	3	186116501	DGKG, ETV5	DGKG	NA	NA	ENSG00000058866	NA	NA	rs7647305-?	rs7647305	0	7647305	intron_variant	FALSE	NR	2e-14	13.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4p12	4	45180510	GNPDA2	PRDX4P1 - THAP12P9	ENSG00000248987	ENSG00000248320	NA	235549	142743	rs10938397-?	rs10938397	0	10938397	intergenic_variant	TRUE	NR	3e-11	10.522878745280337	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.31	6	34859308	UHRF1BP1	UHRF1BP1	NA	NA	ENSG00000065060	NA	NA	rs9469913-?	rs9469913	0	9469913	missense_variant	FALSE	NR	2e-9	8.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p12.3	6	50835337	TFAP2B	TFAP2B	NA	NA	ENSG00000008196	NA	NA	rs987237-?	rs987237	0	987237	intron_variant	FALSE	NR	7e-12	11.154901959985743	(women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p34.1	1	45345193	TESK2	TESK2	NA	NA	ENSG00000070759	NA	NA	rs17853159-A	rs17853159	0	17853159	missense_variant	FALSE	0.081	6e-15	14.221848749616356	NA	0.05152379	[0.039-0.064] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.081	NA	0.05152379
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p13.3	1	111190089	DENND2D	DENND2D	NA	NA	ENSG00000162777	NA	NA	rs2209457-A	rs2209457	0	2209457	intron_variant	FALSE	0.3322	5e-17	16.30102999566398	NA	0.03234826	[0.025-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3322	NA	0.03234826
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p13.2	1	112567997	ST7L	ST7L	NA	NA	ENSG00000007341	NA	NA	rs1001494-C	rs1001494	0	1001494	intron_variant	FALSE	0.4748	2e-13	12.698970004336019	NA	0.02645378	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4748	NA	0.02645378
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p12	1	117608080	FAM46C	TENT5C	NA	NA	ENSG00000183508	NA	NA	rs35986908-TA	rs35986908	0	35986908	intron_variant	FALSE	0.2153	4e-15	14.397940008672037	NA	0.03491363	[0.026-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2153	NA	0.03491363
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q21.3	1	154119580	NUP210L	NUP210L	NA	NA	ENSG00000143552	NA	NA	rs2494663-A	rs2494663	0	2494663	intron_variant	FALSE	0.5502	5e-9	8.301029995663981	NA	0.02120509	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5502	NA	0.02120509
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q23.1	1	156899922	PEAR1	PEAR1	NA	NA	ENSG00000187800	NA	NA	rs12041331-A	rs12041331	0	12041331	intron_variant	FALSE	0.0865	6e-34	33.221848749616356	NA	0.07835613	[0.066-0.091] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0865	NA	0.07835613
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q23.1	1	156908681	PEAR1	PEAR1	NA	NA	ENSG00000187800	NA	NA	rs77795865-T	rs77795865	0	77795865	missense_variant	FALSE	0.035	2e-9	8.698970004336019	NA	0.060348	[0.041-0.08] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.035	NA	0.060348
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q23.1	1	156911263	PEAR1	PEAR1	NA	NA	ENSG00000187800	NA	NA	rs146377491-T	rs146377491	0	146377491	intron_variant	FALSE	0.0959	1e-20	20	NA	0.05809584	[0.046-0.07] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0959	NA	0.05809584
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q23.2	1	159922298	TAGLN2	TAGLN2	NA	NA	ENSG00000158710	NA	NA	rs2789422-A	rs2789422	0	2789422	intron_variant	FALSE	0.419	6e-17	16.221848749616356	NA	0.03053915	[0.023-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.419	NA	0.03053915
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q23.3	1	161219103	FCER1G	FCER1G	NA	NA	ENSG00000158869	NA	NA	rs3557-G	rs3557	0	3557	3_prime_UTR_variant	FALSE	0.0911	2e-13	12.698970004336019	NA	0.04672268	[0.034-0.059] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0911	NA	0.04672268
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q24.3	1	171675446	PFN1P1	PFN1P1 - RPL4P3	ENSG00000233328	ENSG00000230364	NA	4507	7682	rs236907-A	rs236907	0	236907	intergenic_variant	TRUE	0.2044	1e-13	13	NA	0.03258774	[0.024-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2044	NA	0.03258774
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q24.3	1	171925452	DNM3	DNM3	NA	NA	ENSG00000197959	NA	NA	rs6681480-G	rs6681480	0	6681480	intron_variant	FALSE	0.63	4e-12	11.397940008672037	NA	0.02597416	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.63	NA	0.02597416
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q24.3	1	171966088	DNM3	DNM3	NA	NA	ENSG00000197959	NA	NA	rs78346539-G	rs78346539	0	78346539	intron_variant	FALSE	0.0161	7e-45	44.15490195998574	NA	0.2039364	[0.18-0.23] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0161	NA	0.2039364
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q24.3	1	171970501	DNM3	DNM3	NA	NA	ENSG00000197959	NA	NA	rs2038480-T	rs2038480	0	2038480	intron_variant	FALSE	0.8024	1e-181	181	NA	0.1305419	[0.12-0.14] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.8024	NA	0.1305419
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q32.1	1	199041592	RP11-16L9.4	LINC01221	NA	NA	ENSG00000235492	NA	NA	rs1434282-T	rs1434282	0	1434282	non_coding_transcript_exon_variant	FALSE	0.726	6e-9	8.221848749616356	NA	0.02375724	[0.016-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.726	NA	0.02375724
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q32.1	1	202940846	ADIPOR1	ADIPOR1	NA	NA	ENSG00000159346	NA	NA	rs7539542-C	rs7539542	0	7539542	3_prime_UTR_variant	FALSE	0.6796	5e-12	11.301029995663981	NA	0.02731183	[0.02-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.6796	NA	0.02731183
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q32.1	1	204982081	NFASC	NFASC	NA	NA	ENSG00000163531	NA	NA	rs2278796-T	rs2278796	0	2278796	intron_variant	FALSE	0.3076	1e-28	28	NA	0.04339685	[0.036-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3076	NA	0.04339685
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q32.1	1	205240617	TMCC2	TMCC2	NA	NA	ENSG00000133069	NA	NA	rs896322-G	rs896322	0	896322	intron_variant	FALSE	0.8786	7e-76	75.15490195998575	NA	0.1017926	[0.091-0.113] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.8786	NA	0.1017926
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q32.1	1	205275844	TMCC2	TMCC2	NA	NA	ENSG00000133069	NA	NA	rs1172129-A	rs1172129	0	1172129	intron_variant	FALSE	0.3879	1e-210	210	NA	0.1144109	[0.11-0.12] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3879	NA	0.1144109
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q32.2	1	207107394	C4BPA	C4BPA	NA	NA	ENSG00000123838	NA	NA	rs12065624-T	rs12065624	0	12065624	intron_variant	FALSE	0.0665	4e-12	11.397940008672037	NA	0.05033371	[0.036-0.065] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0665	NA	0.05033371
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q44	1	247549001	GCSAML	GCSAML	NA	NA	ENSG00000169224	NA	NA	rs41315846-C	rs41315846	0	41315846	intron_variant	FALSE	0.4763	3e-54	53.52287874528034	NA	0.05691697	[0.05-0.064] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4763	NA	0.05691697
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q44	1	247556467	GCSAML	GCSAML	NA	NA	ENSG00000169224	NA	NA	rs56043070-A	rs56043070	0	56043070	splice_donor_variant	FALSE	0.0712	1e-60	60	NA	0.1148954	[0.1-0.13] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0712	NA	0.1148954
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	NA	NA	NA	TRIM58	NA	NA	NA	NA	NA	NA	chr1:248020556-C	chr1:248020556	0	NA	NA	TRUE	0.7614	8e-63	62.096910013008056	NA	0.07193681	[0.064-0.08] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.7614	NA	0.07193681
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q44	1	247875992	TRIM58	TRIM58	NA	NA	ENSG00000162722	NA	NA	rs1339847-A	rs1339847	0	1339847	missense_variant	FALSE	0.1103	4e-48	47.39794000867204	NA	0.08377635	[0.073-0.095] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1103	NA	0.08377635
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1q44	1	247876149	TRIM58	TRIM58	NA	NA	ENSG00000162722	NA	NA	rs3811444-T	rs3811444	0	3811444	missense_variant	FALSE	0.3348	2e-62	61.69897000433602	NA	0.06369665	[0.056-0.071] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3348	NA	0.06369665
2018-01-09	26545403	Bei JX	2016-01-01	Cancer Epidemiol Biomarkers Prev	www.ncbi.nlm.nih.gov/pubmed/26545403	A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.	Nasopharyngeal carcinoma	2,152 Chinese ancestry cases, 3,740 Chinese ancestry controls	4,716 Chinese ancestry cases, 5,379 Chinese ancestry controls	5p15.33	5	1342599	CLPTM1L, TERT	CLPTM1L	NA	NA	ENSG00000049656	NA	NA	rs31489-?	rs31489	0	31489	intron_variant	FALSE	NR	6e-13	12.221848749616356	NA	1.2345679	NA	Illumina [Sequenom custom array used in replication] (imputed)	N	nasopharyngeal neoplasm	http://www.ebi.ac.uk/efo/EFO_0004252	GCST005113	Genome-wide genotyping array	NA	1.2345679	NA
2018-01-09	26545403	Bei JX	2016-01-01	Cancer Epidemiol Biomarkers Prev	www.ncbi.nlm.nih.gov/pubmed/26545403	A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.	Nasopharyngeal carcinoma	2,152 Chinese ancestry cases, 3,740 Chinese ancestry controls	4,716 Chinese ancestry cases, 5,379 Chinese ancestry controls	3q26.2	3	169364845	MECOM	MECOM	NA	NA	ENSG00000085276	NA	NA	rs6774494-?	rs6774494	0	6774494	intron_variant	FALSE	NR	2e-12	11.698970004336019	NA	1.1904762	NA	Illumina [Sequenom custom array used in replication] (imputed)	N	nasopharyngeal neoplasm	http://www.ebi.ac.uk/efo/EFO_0004252	GCST005113	Genome-wide genotyping array	NA	1.1904762	NA
2018-01-09	26545403	Bei JX	2016-01-01	Cancer Epidemiol Biomarkers Prev	www.ncbi.nlm.nih.gov/pubmed/26545403	A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.	Nasopharyngeal carcinoma	2,152 Chinese ancestry cases, 3,740 Chinese ancestry controls	4,716 Chinese ancestry cases, 5,379 Chinese ancestry controls	13q12.12	13	23631056	TNFRSF19	TNFRSF19	NA	NA	ENSG00000127863	NA	NA	rs9510787-?	rs9510787	0	9510787	intron_variant	FALSE	NR	5e-10	9.301029995663981	NA	1.16	NA	Illumina [Sequenom custom array used in replication] (imputed)	N	nasopharyngeal neoplasm	http://www.ebi.ac.uk/efo/EFO_0004252	GCST005113	Genome-wide genotyping array	NA	1.16	NA
2018-01-09	26545403	Bei JX	2016-01-01	Cancer Epidemiol Biomarkers Prev	www.ncbi.nlm.nih.gov/pubmed/26545403	A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.	Nasopharyngeal carcinoma	2,152 Chinese ancestry cases, 3,740 Chinese ancestry controls	4,716 Chinese ancestry cases, 5,379 Chinese ancestry controls	9p21.3	9	22043927	CDKN2A, CDKN2B	CDKN2B-AS1	NA	NA	ENSG00000240498	NA	NA	rs1412829-?	rs1412829	0	1412829	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	1.25	NA	Illumina [Sequenom custom array used in replication] (imputed)	N	nasopharyngeal neoplasm	http://www.ebi.ac.uk/efo/EFO_0004252	GCST005113	Genome-wide genotyping array	NA	1.25	NA
2018-01-09	26545403	Bei JX	2016-01-01	Cancer Epidemiol Biomarkers Prev	www.ncbi.nlm.nih.gov/pubmed/26545403	A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.	Nasopharyngeal carcinoma	2,152 Chinese ancestry cases, 3,740 Chinese ancestry controls	4,716 Chinese ancestry cases, 5,379 Chinese ancestry controls	9p21.3	9	21974219	C9orf53, CDKN2A	CDKN2A	NA	NA	ENSG00000147889	NA	NA	rs3731239-?	rs3731239	0	3731239	intron_variant	FALSE	NR	1e-6	6	NA	1.1904762	NA	Illumina [Sequenom custom array used in replication] (imputed)	N	nasopharyngeal neoplasm	http://www.ebi.ac.uk/efo/EFO_0004252	GCST005113	Genome-wide genotyping array	NA	1.1904762	NA
2018-01-09	26545403	Bei JX	2016-01-01	Cancer Epidemiol Biomarkers Prev	www.ncbi.nlm.nih.gov/pubmed/26545403	A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.	Nasopharyngeal carcinoma	2,152 Chinese ancestry cases, 3,740 Chinese ancestry controls	4,716 Chinese ancestry cases, 5,379 Chinese ancestry controls	9p21.3	9	22068653	CDKN2A, CDKN2B	CDKN2B-AS1	NA	NA	ENSG00000240498	NA	NA	rs4977756-?	rs4977756	0	4977756	intron_variant	FALSE	NR	7e-7	6.154901959985743	NA	1.1494253	NA	Illumina [Sequenom custom array used in replication] (imputed)	N	nasopharyngeal neoplasm	http://www.ebi.ac.uk/efo/EFO_0004252	GCST005113	Genome-wide genotyping array	NA	1.1494253	NA
2018-01-09	26545403	Bei JX	2016-01-01	Cancer Epidemiol Biomarkers Prev	www.ncbi.nlm.nih.gov/pubmed/26545403	A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.	Nasopharyngeal carcinoma	2,152 Chinese ancestry cases, 3,740 Chinese ancestry controls	4,716 Chinese ancestry cases, 5,379 Chinese ancestry controls	9p21.3	9	22003368	CDKN2A, CDKN2B	CDKN2B, CDKN2B-AS1	NA	NA	ENSG00000147883, ENSG00000240498	NA	NA	rs1063192-?	rs1063192	0	1063192	3_prime_UTR_variant	FALSE	NR	8e-7	6.096910013008056	NA	1.1627907	NA	Illumina [Sequenom custom array used in replication] (imputed)	N	nasopharyngeal neoplasm	http://www.ebi.ac.uk/efo/EFO_0004252	GCST005113	Genome-wide genotyping array	NA	1.1627907	NA
2018-01-09	26545403	Bei JX	2016-01-01	Cancer Epidemiol Biomarkers Prev	www.ncbi.nlm.nih.gov/pubmed/26545403	A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.	Nasopharyngeal carcinoma	2,152 Chinese ancestry cases, 3,740 Chinese ancestry controls	4,716 Chinese ancestry cases, 5,379 Chinese ancestry controls	5p15.33	5	1299910	CLPTM1L, TERT	TERT - MIR4457	ENSG00000164362	ENSG00000263670	NA	4842	9400	rs2853668-?	rs2853668	0	2853668	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	NA	1.12	NA	Illumina [Sequenom custom array used in replication] (imputed)	N	nasopharyngeal neoplasm	http://www.ebi.ac.uk/efo/EFO_0004252	GCST005113	Genome-wide genotyping array	NA	1.12	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q11.2	5	56565532	MAP3K1	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs13173241-A	rs13173241	0	13173241	intron_variant	FALSE	0.1961	2e-6	5.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.1961	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p36.13	1	16981663	MFAP2	MFAP2 - ATP13A2	ENSG00000117122	ENSG00000159363	NA	1031	4295	rs9435732-T	rs9435732	0	9435732	intron_variant	TRUE	0.2658	3e-19	18.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.2658	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p36.13	1	16981663	MFAP2	MFAP2 - ATP13A2	ENSG00000117122	ENSG00000159363	NA	1031	4295	rs9435732-T	rs9435732	0	9435732	intron_variant	TRUE	0.2658	2e-12	11.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.2658	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p36.13	1	16981663	MFAP2	MFAP2 - ATP13A2	ENSG00000117122	ENSG00000159363	NA	1031	4295	rs9435732-T	rs9435732	0	9435732	intron_variant	TRUE	0.2658	1e-8	8	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.2658	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8q13.3	8	71601993	MSC	EYA1 - NA	ENSG00000104313	NA	NA	9968	NA	rs12679556-T	rs12679556	0	12679556	intergenic_variant	TRUE	0.7067	1e-7	7	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7067	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7p15.2	7	25817905	NFE2L3	NA	NA	NA	NA	NA	NA	rs4141278-T	rs4141278	0	4141278	intergenic_variant	TRUE	0.7935	3e-14	13.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7935	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7p15.2	7	25817905	NFE2L3	NA	NA	NA	NA	NA	NA	rs4141278-T	rs4141278	0	4141278	intergenic_variant	TRUE	0.7935	2e-11	10.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7935	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8p21.2	8	23745811	NKX2-6	NKX2-6 - STC1	ENSG00000180053	ENSG00000159167	NA	39055	96118	rs7830933-A	rs7830933	0	7830933	intron_variant	TRUE	0.7571	3e-10	9.522878745280337	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7571	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p21.1	3	52532998	NT5DC2	NT5DC2	NA	NA	ENSG00000168268	NA	NA	rs12489828-T	rs12489828	0	12489828	intron_variant	FALSE	0.5401	3e-7	6.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5401	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p21.1	3	52532998	NT5DC2	NT5DC2	NA	NA	ENSG00000168268	NA	NA	rs12489828-T	rs12489828	0	12489828	intron_variant	FALSE	0.5401	1e-6	6	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5401	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9q21.13	9	75927370	PCSK5	PCSK5	NA	NA	ENSG00000099139	NA	NA	rs11144688-A	rs11144688	0	11144688	intron_variant	FALSE	0.1159	5e-6	5.301029995663981	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.1159	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	19q13.11	19	33402102	PEPD	PEPD	NA	NA	ENSG00000124299	NA	NA	rs3786897-A	rs3786897	0	3786897	intron_variant	FALSE	0.5764	3e-7	6.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5764	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	4q21.21	4	81239194	PRKG2	PRKG2 - RNU5A-2P	ENSG00000138669	ENSG00000207065	NA	23972	95109	rs2197271-C	rs2197271	0	2197271	intergenic_variant	TRUE	0.7215	2e-9	8.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7215	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	4q21.21	4	81239194	PRKG2	PRKG2 - RNU5A-2P	ENSG00000138669	ENSG00000207065	NA	23972	95109	rs2197271-C	rs2197271	0	2197271	intergenic_variant	TRUE	0.7215	2e-6	5.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7215	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	20p13	20	4586042	PRNP	NA - RPS4XP2	NA	ENSG00000226948	NA	NA	41716	rs6076699-A	rs6076699	0	6076699	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	NA	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9q22.32	9	95493953	PTCH1	PTCH1	NA	NA	ENSG00000185920	NA	NA	rs473902-T	rs473902	0	473902	intron_variant	FALSE	0.918	9e-8	7.045757490560675	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.918	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5p13.2	5	34718238	RAI14	RAI14	NA	NA	ENSG00000039560	NA	NA	rs1545348-T	rs1545348	0	1545348	intron_variant	FALSE	NR	5e-7	6.301029995663981	(EA,men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	NA	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q22.33	6	127131790	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs2745353-T	rs2745353	0	2745353	intron_variant	FALSE	0.5202	3e-12	11.522878745280337	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5202	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q22.33	6	127131790	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs2745353-T	rs2745353	0	2745353	intron_variant	FALSE	0.5202	2e-11	10.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5202	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q21.2	1	149920979	SF3B4	SV2A - SF3B4	ENSG00000159164	ENSG00000143368	NA	3135	2338	rs11205277-A	rs11205277	0	11205277	intergenic_variant	TRUE	0.596	4e-14	13.397940008672037	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.596	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q21.2	1	149920979	SF3B4	SV2A - SF3B4	ENSG00000159164	ENSG00000143368	NA	3135	2338	rs11205277-A	rs11205277	0	11205277	intergenic_variant	TRUE	0.596	1e-9	9	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.596	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q21.2	1	149920979	SF3B4	SV2A - SF3B4	ENSG00000159164	ENSG00000143368	NA	3135	2338	rs11205277-A	rs11205277	0	11205277	intergenic_variant	TRUE	0.596	5e-7	6.301029995663981	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.596	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q31.1	5	132342304	SLC22A4	MIR3936HG, SLC22A4	NA	NA	ENSG00000233006, ENSG00000197208	NA	NA	rs272869-A	rs272869	0	272869	intron_variant	FALSE	0.4005	2e-8	7.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.4005	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q22.33	15	67199963	SMAD3	SMAD3 - AAGAB	ENSG00000166949	ENSG00000103591	NA	4790	704	rs7166081-A	rs7166081	0	7166081	regulatory_region_variant	TRUE	0.7599	8e-10	9.096910013008056	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7599	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q22.33	15	67199963	SMAD3	SMAD3 - AAGAB	ENSG00000166949	ENSG00000103591	NA	4790	704	rs7166081-A	rs7166081	0	7166081	regulatory_region_variant	TRUE	0.7599	8e-9	8.096910013008056	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7599	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1p36.32	1	3774964	SMIM1	SMIM1	NA	NA	ENSG00000235169	NA	NA	rs1175550-G	rs1175550	0	1175550	intron_variant	FALSE	0.2321	9e-13	12.045757490560675	NA	0.03013325	[0.022-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2321	NA	0.03013325
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1p36.13	1	16043684	CLCNKB, RP11-5P18.10	CLCNKB	NA	NA	ENSG00000184908	NA	NA	rs140307022-AGCTCT	rs140307022	0	140307022	intron_variant	FALSE	0.3999	1e-9	9	NA	0.02246955	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.3999	NA	0.02246955
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1p34.1	1	45966433	MAST2	MAST2	NA	NA	ENSG00000086015	NA	NA	rs7520050-C	rs7520050	0	7520050	intron_variant	FALSE	0.4138	8e-21	20.096910013008056	NA	0.03441948	[0.027-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4138	NA	0.03441948
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1p12	1	119729854	PHGDH	PHGDH	NA	NA	ENSG00000092621	NA	NA	rs523395-C	rs523395	0	523395	intron_variant	FALSE	0.5339	2e-9	8.698970004336019	NA	0.02186835	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5339	NA	0.02186835
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1q22	1	155208991	MTX1	THBS3, MTX1	NA	NA	ENSG00000169231, ENSG00000173171	NA	NA	rs760077-T	rs760077	0	760077	missense_variant	FALSE	0.6031	2e-11	10.698970004336019	NA	0.02424584	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6031	NA	0.02424584
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1q31.3	1	198612161	intergenic	ATP6V1G3 - PTPRC	ENSG00000263014	ENSG00000081237	NA	71216	26296	rs146310930-T	rs146310930	0	146310930	intergenic_variant	TRUE	0.0291	1e-26	26	NA	0.1136681	[0.093-0.134] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0291	NA	0.1136681
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1q32.1	1	199041592	RP11-16L9.4	LINC01221	NA	NA	ENSG00000235492	NA	NA	rs1434282-T	rs1434282	0	1434282	non_coding_transcript_exon_variant	FALSE	0.7265	7e-29	28.154901959985743	NA	0.04484456	[0.037-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.7265	NA	0.04484456
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1q32.1	1	203312047	BTG2	BTG2 - RNU6-487P	ENSG00000159388	ENSG00000202300	NA	2445	6949	rs17534202-C	rs17534202	0	17534202	intergenic_variant	TRUE	0.5347	3e-12	11.522878745280337	NA	0.02493359	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5347	NA	0.02493359
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1q32.1	1	205072824	CNTN2	CNTN2	NA	NA	ENSG00000184144	NA	NA	rs6696846-T	rs6696846	0	6696846	non_coding_transcript_exon_variant	FALSE	0.487	2e-12	11.698970004336019	NA	0.02492552	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.487	NA	0.02492552
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1q32.2	1	209763286	TRAF3IP3	TRAF3IP3	NA	NA	ENSG00000009790	NA	NA	rs6540556-A	rs6540556	0	6540556	intron_variant	FALSE	0.2311	6e-10	9.221848749616356	NA	0.02622983	[0.018-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2311	NA	0.02622983
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1q32.3	1	214007378	PROX1	PROX1	NA	NA	ENSG00000117707	NA	NA	rs3767844-G	rs3767844	0	3767844	intron_variant	FALSE	0.2877	1e-16	16	NA	0.03275736	[0.025-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2877	NA	0.03275736
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1q42.2	1	231396566	EGLN1	EGLN1	NA	NA	ENSG00000135766	NA	NA	rs508618-A	rs508618	0	508618	intron_variant	FALSE	0.8057	2e-9	8.698970004336019	NA	0.02707177	[0.018-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.8057	NA	0.02707177
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1q42.2	1	231422308	EGLN1	EGLN1 - SNRPD2P2	ENSG00000135766	ENSG00000223982	NA	21	53648	rs533281866-C	rs533281866	0	533281866	intron_variant	TRUE	0.0215	8e-20	19.096910013008056	NA	0.11432199999999999	[0.09-0.139] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0215	NA	0.11432199999999999
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	1q44	1	247876149	TRIM58	TRIM58	NA	NA	ENSG00000162722	NA	NA	rs3811444-T	rs3811444	0	3811444	missense_variant	FALSE	0.336	1e-29	29	NA	0.04242943	[0.035-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.336	NA	0.04242943
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p25.1	2	8614076	AC011747.6	SNRPEP5 - ID2-AS1	ENSG00000225642	ENSG00000235092	NA	10717	52560	rs4669306-A	rs4669306	0	4669306	intron_variant	TRUE	0.6376	5e-10	9.301029995663981	NA	0.02294696	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6376	NA	0.02294696
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p24.1	2	23674855	KLHL29	KLHL29	NA	NA	ENSG00000119771	NA	NA	rs56262900-A	rs56262900	0	56262900	intron_variant	FALSE	0.1027	2e-21	20.69897000433602	NA	0.0557843	[0.044-0.067] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1027	NA	0.0557843
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p23.3	2	27518370	GCKR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs780094-C	rs780094	0	780094	intron_variant	FALSE	0.6165	8e-9	8.096910013008056	NA	0.02097104	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6165	NA	0.02097104
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p21	2	46066687	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs114948639-T	rs114948639	0	114948639	intron_variant	FALSE	0.0127	3e-15	14.522878745280337	NA	0.1288778	[0.097-0.161] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0127	NA	0.1288778
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p21	2	46088377	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs71422190-G	rs71422190	0	71422190	intron_variant	FALSE	0.0805	2e-39	38.69897000433602	NA	0.08576571	[0.073-0.099] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0805	NA	0.08576571
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p21	2	46122132	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs12623399-C	rs12623399	0	12623399	intron_variant	FALSE	0.0586	1e-24	24	NA	0.07733426	[0.063-0.092] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0586	NA	0.07733426
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p21	2	46133768	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs10168349-C	rs10168349	0	10168349	intron_variant	FALSE	0.3309	4e-66	65.39794000867204	NA	0.06419597	[0.057-0.072] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.3309	NA	0.06419597
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p16.1	2	58757735	LINC01122	LINC01122	NA	NA	ENSG00000233723	NA	NA	rs10865309-T	rs10865309	0	10865309	intron_variant	FALSE	0.1382	3e-10	9.522878745280337	NA	0.03267414	[0.023-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1382	NA	0.03267414
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p16.1	2	60402304	intergenic	MIR4432HG	NA	NA	ENSG00000228590	NA	NA	rs5831579-T	rs5831579	1	3059421	intron_variant	FALSE	0.4122	7e-31	30.154901959985743	NA	0.04199508	[0.035-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4122	NA	0.04199508
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p16.1	2	60477604	BCL11A	BCL11A	NA	NA	ENSG00000119866	NA	NA	rs6731647-G	rs6731647	0	6731647	intron_variant	FALSE	0.4523	7e-28	27.154901959985743	NA	0.03959024	[0.032-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4523	NA	0.03959024
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p15	2	62167634	RP11-270B14.1	COMMD1 - B3GNT2	ENSG00000173163	ENSG00000170340	NA	20387	28481	rs35014657-CA	rs35014657	0	35014657	intergenic_variant	TRUE	0.3417	2e-12	11.698970004336019	NA	0.02624446	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.3417	NA	0.02624446
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128194145	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2811511-A	rs2811511	0	2811511	non_coding_transcript_exon_variant	FALSE	0.161	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.161	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128275593	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2811528-A	rs2811528	0	2811528	intron_variant	FALSE	0.16	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128259023	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955096-A	rs2955096	0	2955096	intron_variant	FALSE	0.16	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128196614	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2687730-T	rs2687730	0	2687730	intron_variant	FALSE	0.151	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.151	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128279069	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2811381-A	rs2811381	0	2811381	intron_variant	FALSE	0.16	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	9p24.3	9	306277	DOCK8	DOCK8	NA	NA	ENSG00000107099	NA	NA	rs35381637-A	rs35381637	0	35381637	intron_variant	FALSE	0.16	3e-6	5.522878745280337	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	18q12.2	18	35619952	GALNT1	GALNT1	NA	NA	ENSG00000141429	NA	NA	rs12959333-T	rs12959333	0	12959333	intron_variant	FALSE	0.87	5e-6	5.301029995663981	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.87	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78486611	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs12903285-A	rs12903285	0	12903285	intron_variant	FALSE	0.465	1e-10	10	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.465	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144504600	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	67638	rs1960493-A	rs1960493	0	1960493	intron_variant	TRUE	0.342	1e-10	10	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.342	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144509941	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	62297	rs1512283-T	rs1512283	0	1512283	intron_variant	TRUE	0.342	1e-10	10	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.342	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78427159	Intergenic	CRABP1 - IREB2	ENSG00000166426	ENSG00000136381	NA	78934	10272	rs72736802-A	rs72736802	0	72736802	regulatory_region_variant	TRUE	0.597	3e-10	9.522878745280337	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.597	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78576056	CHRNA5	CHRNA5	NA	NA	ENSG00000169684	NA	NA	rs2456020-T	rs2456020	0	2456020	intron_variant	FALSE	0.286	2e-9	8.698970004336019	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.286	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144442422	Intergenic	NA	NA	NA	NA	NA	NA	rs12499125-A	rs12499125	0	12499125	intron_variant	TRUE	0.278	4e-9	8.397940008672037	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.278	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144436675	Intergenic	NA	NA	NA	NA	NA	NA	rs149774458-C	rs149774458	1	12498434	intron_variant	TRUE	0.278	4e-9	8.397940008672037	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.278	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144432849	Intergenic	NA	NA	NA	NA	NA	NA	rs34490121-A	rs34490121	0	34490121	intron_variant	TRUE	0.278	5e-9	8.301029995663981	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.278	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144453608	Intergenic	NA	NA	NA	NA	NA	NA	rs6828795-T	rs6828795	0	6828795	intron_variant	TRUE	0.281	6e-9	8.221848749616356	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.281	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144437576	Intergenic	NDUFB4P12 - NA	ENSG00000124399	NA	NA	100538225	NA	rs140908948-A	rs140908948	1	12507344	intron_variant	TRUE	0.276	7e-9	8.154901959985743	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.276	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144394135	Intergenic	NA	NA	NA	NA	NA	NA	rs7673195-A	rs7673195	0	7673195	intron_variant	TRUE	0.262	2e-8	7.698970004336019	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.262	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q22.2	11	102850214	Intergenic	MMP3 - MMP12	ENSG00000149968	ENSG00000262406	NA	6605	12522	rs626750-A	rs626750	0	626750	regulatory_region_variant	TRUE	0.198	6e-8	7.221848749616356	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.198	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	19q13.2	19	40842093	Intergenic	CYP2F2P - CYP2A6	ENSG00000237118	ENSG00000255974	NA	15321	1448	rs60446182-A	rs60446182	1	4001925	intron_variant	TRUE	0.548	1e-7	7	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.548	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	19q13.2	19	40840863	Intergenic	CYP2F2P - CYP2A6	ENSG00000237118	ENSG00000255974	NA	14091	2678	rs2316205-T	rs2316205	0	2316205	non_coding_transcript_exon_variant	TRUE	0.545	1e-7	7	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.545	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128260658	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955098-T	rs2955098	0	2955098	intron_variant	FALSE	0.162	7e-7	6.154901959985743	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.162	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128338054	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs6798749-A	rs6798749	0	6798749	intron_variant	FALSE	0.326	9e-7	6.045757490560675	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.326	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128170699	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs13067650-A	rs13067650	0	13067650	intron_variant	FALSE	0.151	1e-6	6	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.151	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128168114	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs10934850-A	rs10934850	0	10934850	intron_variant	FALSE	0.678	1e-6	6	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.678	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	1q43	1	238577059	NR	KRT18P32 - NA	ENSG00000215149	NA	NA	84415	NA	rs77950315-A	rs77950315	0	77950315	intergenic_variant	TRUE	0.0400777	4e-6	5.3979400086720375	NA	1.8343211	[1.1-2.57] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.0400777	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	2q32.1	2	187947170	NR	LINC01090	NA	NA	ENSG00000231689	NA	NA	rs77576211-C	rs77576211	0	77576211	intron_variant	FALSE	0.0955922	2e-6	5.698970004336019	NA	1.1911854	[0.73-1.65] unit decrease	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.0955922	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	3p25.3	3	8755176	CAV3, OXTR	CAV3, OXTR	NA	NA	ENSG00000182533, ENSG00000180914	NA	NA	rs11718289-T	rs11718289	0	11718289	intron_variant	FALSE	0.353661	3e-7	6.522878745280337	NA	0.8016812	[0.52-1.09] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.353661	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	3p26.3	3	1100097	NR	CNTN6	NA	NA	ENSG00000134115	NA	NA	rs139701434-A	rs139701434	0	139701434	intron_variant	FALSE	0.020665	2e-6	5.698970004336019	NA	2.537798	[1.55-3.52] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.020665	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	3p26.3	3	219074	NR	CHL1	NA	NA	ENSG00000134121	NA	NA	rs35210560-C	rs35210560	1	35121062	intron_variant	FALSE	0.283743	3e-6	5.522878745280337	NA	0.68471986	[0.42-0.95] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.283743	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	4p16.3	4	48361	NR	NA - BNIP3P41	NA	ENSG00000248302	NA	NA	735	rs2859208-T	rs2859208	0	2859208	intergenic_variant	TRUE	0.432638	9e-6	5.045757490560675	NA	0.88785464	[0.52-1.26] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.432638	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	5q13.3	5	74517389	NR	LINC01331	NA	NA	ENSG00000248673	NA	NA	rs151146085-T	rs151146085	0	151146085	intron_variant	FALSE	0.0201408	9e-6	5.045757490560675	NA	2.3236868	[1.35-3.29] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.0201408	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	6q22.33	6	128659533	NR	Y_RNA - NA	ENSG00000199964	NA	NA	75042	NA	rs542925-T	rs542925	0	542925	regulatory_region_variant	TRUE	0.330097	2e-6	5.698970004336019	NA	0.7203378	[0.44-1] unit decrease	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.330097	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	6q15	6	90402942	NR	MIR4464 - NA	ENSG00000266760	NA	NA	90109	NA	rs4706368-C	rs4706368	0	4706368	regulatory_region_variant	TRUE	0.43217	8e-6	5.096910013008056	NA	0.65017843	[0.38-0.92] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.43217	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	6p12.3	6	49772882	NR	CRISP3 - PGK2	ENSG00000096006	ENSG00000170950	NA	28445	12778	rs186646553-T	rs186646553	0	186646553	intron_variant	TRUE	0.0220922	9e-6	5.045757490560675	NA	2.267864	[1.32-3.22] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.0220922	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	7q36.3	7	156034162	NR	NA	NA	NA	NA	NA	NA	rs77413038-A	rs77413038	0	77413038	regulatory_region_variant	TRUE	0.0661845	9e-6	5.045757490560675	NA	1.1706738	[0.68-1.66] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.0661845	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	8p21.3	8	19292776	NR	NA - SH2D4A	NA	ENSG00000104611	NA	NA	20917	rs1814981-C	rs1814981	0	1814981	intergenic_variant	TRUE	0.291136	6e-7	6.221848749616356	NA	0.7958612	[0.5-1.09] unit decrease	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.291136	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	8q21.3	8	86257307	NR	SLC7A13	NA	NA	ENSG00000164893	NA	NA	rs12681287-A	rs12681287	0	12681287	intron_variant	FALSE	0.364432	1e-6	6	NA	0.6621911	[0.41-0.91] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.364432	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	8q23.3	8	113497020	NR	CSMD3 - NA	ENSG00000164796	NA	NA	60081	NA	rs139683691-C	rs139683691	0	139683691	intergenic_variant	TRUE	0.0605971	4e-6	5.3979400086720375	NA	1.3790523	[0.83-1.93] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.0605971	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	8p21.3	8	22986484	NR	PEBP4	NA	NA	ENSG00000134020	NA	NA	rs2466211-C	rs2466211	0	2466211	intron_variant	FALSE	0.376447	4e-6	5.3979400086720375	NA	0.64253575	[0.39-0.9] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.376447	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	8q24.23	8	138298624	NR	FAM135B	NA	NA	ENSG00000147724	NA	NA	rs60134676-A	rs60134676	0	60134676	intron_variant	FALSE	0.0855728	6e-6	5.221848749616356	NA	1.1590749	[0.68-1.63] unit decrease	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.0855728	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	9q34.11	9	129351652	NR	LINC01503	NA	NA	ENSG00000233901	NA	NA	rs73621547-C	rs73621547	0	73621547	intron_variant	FALSE	0.0991553	3e-6	5.522878745280337	NA	1.100957	[0.67-1.53] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.0991553	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	9q21.31	9	79259840	NR	KDM4C - NA	ENSG00000107077	NA	NA	72084192	NA	rs35198810-C	rs35198810	0	35198810	intergenic_variant	TRUE	0.0610437	4e-6	5.3979400086720375	NA	1.3421149000000001	[0.81-1.88] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.0610437	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	rs7858225-G	rs7858225	0	7858225	intergenic_variant	TRUE	0.49016	8e-6	5.096910013008056	NA	0.6040948	[0.35-0.85] unit decrease	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.49016	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	10q22.1	10	70292956	NR	NPFFR1 - LRRC20	ENSG00000148734	ENSG00000172731	NA	8952	6014	rs10823514-T	rs10823514	0	10823514	intergenic_variant	TRUE	0.281233	3e-6	5.522878745280337	NA	0.6752977	[0.41-0.94] unit decrease	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.281233	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	11p15.4	11	10990785	NR	ZBED5-AS1 - LINC02752	ENSG00000247271	ENSG00000254401	NA	81813	30098	rs10770152-T	rs10770152	0	10770152	TF_binding_site_variant	TRUE	0.368932	3e-6	5.522878745280337	NA	0.6548911	[0.4-0.91] unit decrease	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.368932	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	12q21.1	12	73001289	NR	NA	NA	NA	NA	NA	NA	rs12319493-T	rs12319493	0	12319493	regulatory_region_variant	TRUE	0.23799	4e-6	5.3979400086720375	NA	0.7028829	[0.42-0.98] unit decrease	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.23799	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	13q12.13	13	26998157	NR	RPS21P8 - RPS20P32	ENSG00000223782	ENSG00000218198	NA	20368	19397	rs77743965-C	rs77743965	0	77743965	regulatory_region_variant	TRUE	0.078932	3e-6	5.522878745280337	NA	1.2075597	[0.73-1.68] unit decrease	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.078932	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	13q33.3	13	109173948	NR	MYO16, MYO16-AS1	NA	NA	ENSG00000041515, ENSG00000236242	NA	NA	rs35729053-TGCG	rs35729053	0	35729053	intron_variant	FALSE	0.170374	8e-6	5.096910013008056	NA	0.80638254	[0.47-1.14] unit decrease	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.170374	NA	NA
2017-11-20	28927378	Qian DC	2017-09-19	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/28927378	Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.	Caudate activity during reward	106 individuals	NA	14q21.1	14	39616355	NR	NA	NA	NA	NA	NA	NA	rs56001627-G	rs56001627	0	56001627	intron_variant	TRUE	0.0631068	5e-6	5.301029995663981	NA	1.3018842	[0.77-1.83] unit increase	Illumina [at least 621854] (imputed)	N	caudate nucleus measurement, functional brain measurement, response to reward	http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396	GCST004970	Genome-wide genotyping array	0.0631068	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of severe pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	11q12.1	11	57084623	NR	OR5BP1P - LRRC55	ENSG00000273255	ENSG00000183908	NA	28491	97124	rs553086-A	rs553086	0	553086	intergenic_variant	TRUE	0.23	3e-6	5.522878745280337	NA	0.92	unit increase	Illumina [8591557] (imputed)	N	fear of severe pain measurement	http://www.ebi.ac.uk/efo/EFO_0008338	GCST004709	Genome-wide genotyping array	0.23	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of severe pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	12p11.21	12	31841806	NR	RNU6-1069P - LINC02422	ENSG00000252421	ENSG00000255760	NA	38716	35163	rs10844026-A	rs10844026	0	10844026	intergenic_variant	TRUE	0.24	8e-7	6.096910013008056	NA	0.95	unit decrease	Illumina [8591557] (imputed)	N	fear of severe pain measurement	http://www.ebi.ac.uk/efo/EFO_0008338	GCST004709	Genome-wide genotyping array	0.24	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of severe pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	12q13.13	12	54490418	NR	GTSF1 - NCKAP1L	ENSG00000170627	ENSG00000123338	NA	16816	7334	rs61923480-C	rs61923480	0	61923480	intron_variant	TRUE	0.02	4e-7	6.3979400086720375	NA	2.52	unit increase	Illumina [8591557] (imputed)	N	fear of severe pain measurement	http://www.ebi.ac.uk/efo/EFO_0008338	GCST004709	Genome-wide genotyping array	0.02	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of severe pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	12q15	12	70877653	NR	PTPRR	NA	NA	ENSG00000153233	NA	NA	rs61930374-C	rs61930374	0	61930374	intron_variant	FALSE	0.2	5e-7	6.301029995663981	NA	1.09	unit decrease	Illumina [8591557] (imputed)	N	fear of severe pain measurement	http://www.ebi.ac.uk/efo/EFO_0008338	GCST004709	Genome-wide genotyping array	0.2	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of severe pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	13q14.3	13	50476691	NR	DLEU1	NA	NA	ENSG00000176124	NA	NA	rs112664965-A	rs112664965	0	112664965	intron_variant	FALSE	0.04	2e-6	5.698970004336019	NA	1.88	unit decrease	Illumina [8591557] (imputed)	N	fear of severe pain measurement	http://www.ebi.ac.uk/efo/EFO_0008338	GCST004709	Genome-wide genotyping array	0.04	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of severe pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	15q21.3	15	53607109	NR	WDR72	NA	NA	ENSG00000166415	NA	NA	rs7178691-A	rs7178691	0	7178691	intron_variant	FALSE	0.32	3e-6	5.522878745280337	NA	0.82	unit decrease	Illumina [8591557] (imputed)	N	fear of severe pain measurement	http://www.ebi.ac.uk/efo/EFO_0008338	GCST004709	Genome-wide genotyping array	0.32	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of severe pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	17p12	17	12695685	NR	MYOCD-AS1, MYOCD	NA	NA	ENSG00000227274, ENSG00000141052	NA	NA	rs56875752-C	rs56875752	0	56875752	intron_variant	FALSE	0.11	2e-7	6.698970004336019	NA	1.38	unit increase	Illumina [8591557] (imputed)	N	fear of severe pain measurement	http://www.ebi.ac.uk/efo/EFO_0008338	GCST004709	Genome-wide genotyping array	0.11	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of severe pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	19q13.42	19	53302562	NR	FAM90A28P	NA	NA	ENSG00000269118	NA	NA	rs3975333-T	rs3975333	0	3975333	intron_variant	FALSE	0.09	2e-6	5.698970004336019	NA	1.49	unit increase	Illumina [8591557] (imputed)	N	fear of severe pain measurement	http://www.ebi.ac.uk/efo/EFO_0008338	GCST004709	Genome-wide genotyping array	0.09	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	1p13.1	1	116116196	NR	MAB21L3	NA	NA	ENSG00000173212	NA	NA	rs1146361-C	rs1146361	0	1146361	intron_variant	FALSE	0.15	8e-7	6.096910013008056	NA	0.81	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.15	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	2q11.2	2	98835995	NR	CRACDL	NA	NA	ENSG00000196872	NA	NA	rs6542838-C	rs6542838	0	6542838	intron_variant	FALSE	0.44	2e-7	6.698970004336019	NA	0.61	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.44	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	2q36.2	2	224349098	NR	NA - FAM124B	NA	ENSG00000124019	NA	NA	29600	rs113865232-T	rs113865232	0	113865232	intergenic_variant	TRUE	0.01	7e-7	6.154901959985743	NA	2.63	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.01	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	2q37.2	2	236322492	NR	ASB18 - IQCA1	ENSG00000182177	ENSG00000132321	NA	58083	1655	rs13411339-T	rs13411339	0	13411339	intergenic_variant	TRUE	0.03	9e-7	6.045757490560675	NA	1.77	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.03	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	3q11.2	3	97483398	NR	EPHA6	NA	NA	ENSG00000080224	NA	NA	rs9871066-G	rs9871066	0	9871066	intron_variant	FALSE	0.02	3e-7	6.522878745280337	NA	2.56	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.02	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	4q32.1	4	159432070	NR	RAPGEF2 - NA	ENSG00000109756	NA	NA	71896	NA	rs2699039-A	rs2699039	0	2699039	intergenic_variant	TRUE	0.02	4e-7	6.3979400086720375	NA	2.54	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.02	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	6q13	6	71110972	NR	BECN1P2 - U3	ENSG00000219669	ENSG00000221673	NA	34597	15921	rs73746987-T	rs73746987	0	73746987	intergenic_variant	TRUE	0.01	2e-7	6.698970004336019	NA	3.4	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.01	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	6q26	6	161246020	NR	AGPAT4	NA	NA	ENSG00000026652	NA	NA	rs73782827-G	rs73782827	0	73782827	intron_variant	FALSE	0.01	3e-8	7.522878745280337	NA	3.8	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.01	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	6q26	6	161872612	NR	PRKN	NA	NA	ENSG00000185345	NA	NA	rs34139189-G	rs34139189	0	34139189	intron_variant	FALSE	0.14	8e-7	6.096910013008056	NA	0.93	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.14	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	8p21.2	8	25005115	LOC105379330, NEFM, NEFL	NEFL - NA	ENSG00000277586	NA	NA	48394	NA	rs73547001-G	rs73547001	0	73547001	intron_variant	TRUE	0.01	1e-8	8	NA	3.35	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.01	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	8q23.1	8	106055986	NR	ZFPM2-AS1	NA	NA	ENSG00000251003	NA	NA	rs73700552-C	rs73700552	0	73700552	intron_variant	FALSE	0.01	1e-7	7	NA	3.43	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.01	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	8q24.13	8	124405882	TMEM65	TMEM65 - TRMT12	ENSG00000164983	ENSG00000183665	NA	33181	44938	rs113248907-A	rs113248907	0	113248907	intergenic_variant	TRUE	0.01	2e-10	9.698970004336019	NA	3.41	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.01	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	8q24.3	8	144414202	NR	SLC39A4	NA	NA	ENSG00000147804	NA	NA	rs1871535-C	rs1871535	0	1871535	intron_variant	FALSE	0.02	3e-7	6.522878745280337	NA	2.09	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.02	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	10q23.32	10	92050985	NR	CPEB3	NA	NA	ENSG00000107864	NA	NA	rs12252682-C	rs12252682	0	12252682	3_prime_UTR_variant	FALSE	0.02	6e-7	6.221848749616356	NA	2.45	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.02	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	11q13.1	11	64279680	NR	BAD, GPR137	NA	NA	ENSG00000002330, ENSG00000173264	NA	NA	rs687735-A	rs687735	0	687735	intron_variant	FALSE	0.01	9e-7	6.045757490560675	NA	3.26	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.01	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	17q21.2	17	42540620	NR	NAGLU	NA	NA	ENSG00000108784	NA	NA	rs11871659-C	rs11871659	0	11871659	intron_variant	FALSE	0.03	5e-7	6.301029995663981	NA	2.08	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.03	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	20q11.21	20	32088513	NR	HCK	NA	NA	ENSG00000101336	NA	NA	rs2223785-C	rs2223785	0	2223785	intron_variant	FALSE	0.02	3e-7	6.522878745280337	NA	2.8	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.02	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	22q13.31	22	47408493	NR	NA - LINC01644	NA	ENSG00000218357	NA	NA	52806	rs6008192-T	rs6008192	0	6008192	regulatory_region_variant	TRUE	0.01	5e-7	6.301029995663981	NA	2.99	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.01	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of minor pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	Xq25	X	124617909	NR	TENM1	NA	NA	ENSG00000009694	NA	NA	rs73558352-T	rs73558352	0	73558352	intron_variant	FALSE	0.02	5e-7	6.301029995663981	NA	2	unit decrease	Illumina [8591557] (imputed)	N	fear of minor pain measurement	http://www.ebi.ac.uk/efo/EFO_0008340	GCST004708	Genome-wide genotyping array	0.02	NA	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of medical pain (dental)	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	1p31.1	1	74242875	NR	FPGT-TNNI3K, TNNI3K	NA	NA	ENSG00000259030, ENSG00000116783	NA	NA	rs114134414-C	rs114134414	0	114134414	intron_variant	FALSE	0.03	9e-7	6.045757490560675	NA	2.15	unit increase	Illumina [8591557] (imputed)	N	fear of medical pain measurement	http://www.ebi.ac.uk/efo/EFO_0008339	GCST004707	Genome-wide genotyping array	0.03	2.15	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of medical pain (dental)	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr2:99411513-A	chr2:99411513	0	NA	NA	TRUE	0.14	1e-6	6	NA	1.29	unit decrease	Illumina [8591557] (imputed)	N	fear of medical pain measurement	http://www.ebi.ac.uk/efo/EFO_0008339	GCST004707	Genome-wide genotyping array	0.14	1.29	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of medical pain (dental)	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	6q22.33	6	127702236	NR	LINC02536 - THEMIS	ENSG00000281248	ENSG00000275122	NA	20681	5836	rs72965720-C	rs72965720	0	72965720	intergenic_variant	TRUE	0.08	2e-7	6.698970004336019	NA	1.43	unit increase	Illumina [8591557] (imputed)	N	fear of medical pain measurement	http://www.ebi.ac.uk/efo/EFO_0008339	GCST004707	Genome-wide genotyping array	0.08	1.43	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of medical pain (dental)	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	17q11.2	17	31009727	NR	RNF135 - MIR4733HG	ENSG00000181481	ENSG00000264107	NA	9816	81060	rs9901616-T	rs9901616	0	9901616	intron_variant	TRUE	0.03	8e-7	6.096910013008056	NA	2.31	unit decrease	Illumina [8591557] (imputed)	N	fear of medical pain measurement	http://www.ebi.ac.uk/efo/EFO_0008339	GCST004707	Genome-wide genotyping array	0.03	2.31	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of medical pain (dental)	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	19p13.3	19	982968	NR	ARID3A - WDR18	ENSG00000116017	ENSG00000065268	NA	7029	1364	rs10422046-A	rs10422046	0	10422046	TF_binding_site_variant	TRUE	0.11	1e-6	6	NA	1.38	unit increase	Illumina [8591557] (imputed)	N	fear of medical pain measurement	http://www.ebi.ac.uk/efo/EFO_0008339	GCST004707	Genome-wide genotyping array	0.11	1.38	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of medical pain (dental)	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	Xp22.2	X	10041953	NR	WWC3	NA	NA	ENSG00000047644	NA	NA	rs5979239-A	rs5979239	0	5979239	intron_variant	FALSE	0.04	2e-6	5.698970004336019	NA	2.04	unit decrease	Illumina [8591557] (imputed)	N	fear of medical pain measurement	http://www.ebi.ac.uk/efo/EFO_0008339	GCST004707	Genome-wide genotyping array	0.04	2.04	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	6q26	6	161246020	AGPAT4, PARK2	AGPAT4	NA	NA	ENSG00000026652	NA	NA	rs73782827-G	rs73782827	0	73782827	intron_variant	FALSE	0.01	1e-6	6	NA	10.84	unit decrease	Illumina [8591557] (imputed)	N	fear of pain measurement	http://www.ebi.ac.uk/efo/EFO_0008330	GCST004706	Genome-wide genotyping array	0.01	10.84	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	8q24.13	8	124417020	NR	TMEM65 - TRMT12	ENSG00000164983	ENSG00000183665	NA	44319	33800	rs112510117-A	rs112510117	0	112510117	intergenic_variant	TRUE	0.01	7e-7	6.154901959985743	NA	8.44	unit decrease	Illumina [8591557] (imputed)	N	fear of pain measurement	http://www.ebi.ac.uk/efo/EFO_0008330	GCST004706	Genome-wide genotyping array	0.01	8.44	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	10q24.33	10	103564413	NR	NEURL1	NA	NA	ENSG00000107954	NA	NA	rs7084783-G	rs7084783	0	7084783	intron_variant	FALSE	0.49	2e-6	5.698970004336019	NA	1.69	unit decrease	Illumina [8591557] (imputed)	N	fear of pain measurement	http://www.ebi.ac.uk/efo/EFO_0008330	GCST004706	Genome-wide genotyping array	0.49	1.69	NA
2017-09-12	28701861	Randall CL	2017-06-15	Pain Res Manag	www.ncbi.nlm.nih.gov/pubmed/28701861	A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain.	Fear of pain	Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals	NA	17p12	17	12695685	NR	MYOCD-AS1, MYOCD	NA	NA	ENSG00000227274, ENSG00000141052	NA	NA	rs56875752-C	rs56875752	0	56875752	intron_variant	FALSE	0.11	6e-7	6.221848749616356	NA	2.91	unit increase	Illumina [8591557] (imputed)	N	fear of pain measurement	http://www.ebi.ac.uk/efo/EFO_0008330	GCST004706	Genome-wide genotyping array	0.11	2.91	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	4p15.32	4	17386536	NR	SNORA75B - RPS7P6	ENSG00000206780	ENSG00000215278	NA	65654	41160	rs77485526-T	rs77485526	0	77485526	intergenic_variant	TRUE	0.0325	2e-6	5.698970004336019	(EA)	0.0895	[0.052-0.127] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0325	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	15q26.1	15	90965985	NR	RCCD1 - PRC1	ENSG00000166965	ENSG00000198901	NA	2860	55	rs77554484-A	rs77554484	0	77554484	intergenic_variant	TRUE	0.1319	1e-15	15	(EA)	0.0741	[0.056-0.092] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.1319	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	11q23.3	11	117214494	NR	PCSK7	NA	NA	ENSG00000160613	NA	NA	rs77683187-C	rs77683187	0	77683187	non_coding_transcript_exon_variant	FALSE	0.0608	2e-6	5.698970004336019	(EA)	0.0613	[0.036-0.087] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0608	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	2q33.1	2	201502866	NR	C2CD6	NA	NA	ENSG00000155754	NA	NA	rs77688320-G	rs77688320	0	77688320	intron_variant	FALSE	0.1668	3e-9	8.522878745280337	(EA)	0.0489	[0.033-0.065] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.1668	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	6q14.3	6	84379128	NR	NA - LINC01611	NA	ENSG00000231776	NA	NA	41900	rs7768862-A	rs7768862	0	7768862	intergenic_variant	TRUE	0.5075	6e-6	5.221848749616356	(EA)	0.028	[0.016-0.04] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.5075	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	4q24	4	105435604	NR	PPA2	NA	NA	ENSG00000138777	NA	NA	rs77928427-A	rs77928427	0	77928427	intron_variant	FALSE	0.2392	3e-8	7.522878745280337	(EA)	0.04	[0.026-0.054] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.2392	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	7p21.3	7	12721416	NR	ARL4A - NA	ENSG00000122644	NA	NA	30458	NA	rs7810893-C	rs7810893	0	7810893	intergenic_variant	TRUE	0.3487	4e-6	5.3979400086720375	(EA)	0.0299	[0.017-0.043] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.3487	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	8q24.21	8	127677080	NR	NA - CASC11	NA	ENSG00000249375	NA	NA	9263	rs7833090-C	rs7833090	0	7833090	intergenic_variant	TRUE	0.2535	2e-6	5.698970004336019	(EA)	0.0339	[0.02-0.048] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.2535	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	8p12	8	30372068	NR	TUBBP1 - RBPMS-AS1	ENSG00000127589	ENSG00000254109	NA	18550	10051	rs7834448-C	rs7834448	0	7834448	intergenic_variant	TRUE	0.667	7e-6	5.154901959985743	(EA)	0.0309	[0.017-0.044] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.667	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	8q21.13	8	75751646	NR	NA	NA	NA	NA	NA	NA	rs7844233-G	rs7844233	0	7844233	intergenic_variant	TRUE	0.0642	6e-11	10.221848749616356	(EA)	0.0813	[0.057-0.106] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0642	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	11q13.3	11	69516650	NR	LINC01488 - CCND1	ENSG00000285094	ENSG00000110092	NA	21698	124506	rs78540526-T	rs78540526	0	78540526	regulatory_region_variant	TRUE	0.0756	2e-131	130.69897000433602	(EA)	0.2758	[0.25-0.3] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0756	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	3q25.31	3	156800880	NR	LINC00886	NA	NA	ENSG00000240875	NA	NA	rs78579487-GTT	rs78579487	1	35231283	intron_variant	FALSE	0.614	4e-7	6.3979400086720375	(EA)	0.0324	[0.02-0.045] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.614	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	9q22.32	9	95008323	NR	AOPEP	NA	NA	ENSG00000148120	NA	NA	rs7862618-A	rs7862618	0	7862618	intron_variant	FALSE	0.0134	5e-6	5.301029995663981	(EA)	0.1381	[0.079-0.197] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0134	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	10q25.3	10	113127459	NR	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs7906315-G	rs7906315	0	7906315	intron_variant	FALSE	0.6218	2e-8	7.698970004336019	(EA)	0.0357	[0.023-0.048] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.6218	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	10p12.1	10	27080233	NR	ANKRD26	NA	NA	ENSG00000107890	NA	NA	rs7918232-C	rs7918232	0	7918232	intron_variant	FALSE	0.8143	8e-6	5.096910013008056	(EA)	0.036	[0.02-0.052] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.8143	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	11q12.3	11	62126500	NR	INCENP	NA	NA	ENSG00000149503	NA	NA	rs7937840-T	rs7937840	0	7937840	intron_variant	FALSE	0.2591	1e-6	6	(EA)	0.035	[0.021-0.049] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.2591	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	7q21.3	7	98397243	NR	BAIAP2L1	NA	NA	ENSG00000006453	NA	NA	rs79518236-A	rs79518236	0	79518236	intron_variant	FALSE	0.2327	1e-7	7	(EA)	0.0396	[0.025-0.054] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.2327	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	6p25.3	6	1319077	NR	FOXQ1 - LINC01394	ENSG00000164379	ENSG00000281809	NA	4319	2621	rs80199833-T	rs80199833	0	80199833	intergenic_variant	TRUE	0.2071	7e-6	5.154901959985743	(EA)	0.0356	[0.02-0.051] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.2071	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	15q24.2	15	75516399	NR	PTPN9	NA	NA	ENSG00000169410	NA	NA	rs8027365-C	rs8027365	0	8027365	intron_variant	FALSE	0.2707	1e-7	7	(EA)	0.038	[0.024-0.052] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.2707	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	9q33.1	9	116672011	NR	ASTN2	NA	NA	ENSG00000148219	NA	NA	rs803903-G	rs803903	0	803903	intron_variant	FALSE	0.6805	8e-12	11.096910013008056	(EA)	0.0456	[0.032-0.059] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.6805	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	17q25.3	17	81397410	NR	BAHCC1	NA	NA	ENSG00000266074	NA	NA	rs8074440-C	rs8074440	0	8074440	intron_variant	FALSE	0.5239	3e-6	5.522878745280337	(EA)	0.0353	[0.02-0.05] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.5239	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	17q11.2	17	30689342	NR	LRRC37BP1 - RN7SL316P	ENSG00000250462	ENSG00000241631	NA	51876	13162	rs8081187-A	rs8081187	0	8081187	intergenic_variant	TRUE	0.0843	2e-7	6.698970004336019	(EA)	0.0607	[0.038-0.083] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0843	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	17q25.3	17	79797749	NR	CBX8	NA	NA	ENSG00000141570	NA	NA	rs8082452-G	rs8082452	0	8082452	intron_variant	FALSE	0.4562	1e-10	10	(EA)	0.0418	[0.029-0.055] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.4562	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	7q21.3	7	98065546	NR	RN7SL478P - LMTK2	ENSG00000277946	ENSG00000164715	NA	66924	41316	rs847577-A	rs847577	0	847577	intergenic_variant	TRUE	0.4176	6e-6	5.221848749616356	(EA)	0.0284	[0.016-0.041] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.4176	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	14q13.3	14	36808438	NR	SLC25A21	NA	NA	ENSG00000183032	NA	NA	rs848087-G	rs848087	0	848087	intron_variant	FALSE	0.5682	6e-11	10.221848749616356	(EA)	0.0427	[0.03-0.055] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.5682	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118321979	SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126	NA	57490	292354	rs7536458-T	rs7536458	0	7536458	intergenic_variant	TRUE	0.748	7e-17	16.154901959985743	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.748	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118321979	SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126	NA	57490	292354	rs7536458-T	rs7536458	0	7536458	intergenic_variant	TRUE	0.748	3e-10	9.522878745280337	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.748	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118321979	SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126	NA	57490	292354	rs7536458-T	rs7536458	0	7536458	intergenic_variant	TRUE	0.748	2e-8	7.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.748	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	10q24.32	10	102567827	SUFU	SUFU	NA	NA	ENSG00000107882	NA	NA	rs3862030-A	rs3862030	0	3862030	intron_variant	FALSE	0.5599	2e-8	7.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5599	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	10q24.32	10	102567827	SUFU	SUFU	NA	NA	ENSG00000107882	NA	NA	rs3862030-A	rs3862030	0	3862030	intron_variant	FALSE	0.5599	2e-6	5.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5599	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118962811	TBX15, WARS2	TBX15	NA	NA	ENSG00000092607	NA	NA	rs10923712-A	rs10923712	0	10923712	intron_variant	FALSE	0.6025	2e-25	24.69897000433602	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.6025	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118962811	TBX15, WARS2	TBX15	NA	NA	ENSG00000092607	NA	NA	rs10923712-A	rs10923712	0	10923712	intron_variant	FALSE	0.6025	3e-17	16.522878745280337	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.6025	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118962811	TBX15, WARS2	TBX15	NA	NA	ENSG00000092607	NA	NA	rs10923712-A	rs10923712	0	10923712	intron_variant	FALSE	0.6025	3e-11	10.522878745280337	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.6025	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q41	1	218423955	TGFB2	TGFB2	NA	NA	ENSG00000092969	NA	NA	rs12048049-C	rs12048049	0	12048049	intron_variant	FALSE	0.6885	5e-10	9.301029995663981	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.6885	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q41	1	218423955	TGFB2	TGFB2	NA	NA	ENSG00000092969	NA	NA	rs12048049-C	rs12048049	0	12048049	intron_variant	FALSE	0.6885	8e-8	7.096910013008056	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.6885	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9q31.2	9	106128240	TMEM38B	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs9408815-C	rs9408815	0	9408815	intron_variant	FALSE	NR	3e-11	10.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	NA	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9q31.2	9	106138768	TMEM38B	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs9409082-C	rs9409082	0	9409082	intron_variant	FALSE	NR	7e-11	10.154901959985743	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	NA	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	14q32.12	14	91962066	TRIP11	FBLN5 - TRIP11	ENSG00000140092	ENSG00000100815	NA	14079	3925	rs2160077-A	rs2160077	0	2160077	regulatory_region_variant	TRUE	0.4322	3e-8	7.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.4322	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	14q32.12	14	91962066	TRIP11	FBLN5 - TRIP11	ENSG00000140092	ENSG00000100815	NA	14079	3925	rs2160077-A	rs2160077	0	2160077	regulatory_region_variant	TRUE	0.4322	2e-6	5.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.4322	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q25.3	1	184051811	TSEN15	TSEN15	NA	NA	ENSG00000198860	NA	NA	rs2274432-A	rs2274432	0	2274432	missense_variant	FALSE	0.3486	2e-15	14.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.3486	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q25.3	1	184051811	TSEN15	TSEN15	NA	NA	ENSG00000198860	NA	NA	rs2274432-A	rs2274432	0	2274432	missense_variant	FALSE	0.3486	2e-10	9.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.3486	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q25.3	1	184051811	TSEN15	TSEN15	NA	NA	ENSG00000198860	NA	NA	rs2274432-A	rs2274432	0	2274432	missense_variant	FALSE	0.3486	9e-7	6.045757490560675	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.3486	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.1	6	43790159	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	3672	54719	rs998584-A	rs998584	0	998584	regulatory_region_variant	TRUE	0.4672	2e-24	23.69897000433602	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.4672	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.1	6	43790159	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	3672	54719	rs998584-A	rs998584	0	998584	regulatory_region_variant	TRUE	0.4672	1e-13	13	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.4672	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q23	3	141406344	ZBTB38	ZBTB38	NA	NA	ENSG00000177311	NA	NA	rs1344674-A	rs1344674	0	1344674	intron_variant	FALSE	0.5451	1e-14	14	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5451	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q23	3	141406344	ZBTB38	ZBTB38	NA	NA	ENSG00000177311	NA	NA	rs1344674-A	rs1344674	0	1344674	intron_variant	FALSE	0.5451	2e-13	12.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5451	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16q12.1	16	49830880	ZNF423	ZNF423	NA	NA	ENSG00000102935	NA	NA	rs2047937-T	rs2047937	0	2047937	intron_variant	FALSE	0.5057	1e-6	6	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5057	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q41	1	219495884	LYPLA1	LYPLAL1-AS1 - NA	ENSG00000228536	NA	NA	36515	NA	rs765751-C	rs765751	0	765751	intergenic_variant	TRUE	0.611	8e-22	21.096910013008056	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.611	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.33	6	31268790	HLA-C	HLA-C, HLA-C, HLA-C, HLA-C, HLA-C, HLA-C, HLA-C	NA	NA	ENSG00000204525, ENSG00000206435, ENSG00000233841, ENSG00000206452, ENSG00000237022, ENSG00000225691, ENSG00000228299	NA	NA	rs1049281-C	rs1049281	0	1049281	3_prime_UTR_variant	FALSE	0.652	2e-10	9.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.652	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q22.33	6	127133993	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs7766106-T	rs7766106	0	7766106	intron_variant	FALSE	0.486	3e-34	33.52287874528034	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.486	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	13q13.1	13	32601963	NR	PDS5B	NA	NA	ENSG00000083642	NA	NA	rs113855064-C	rs113855064	0	113855064	intron_variant	FALSE	0.0081	1e-7	7	(EA)	0.1877	[0.12-0.26] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0081	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	6p12.1	6	54862053	NR	FAM83B	NA	NA	ENSG00000168143	NA	NA	rs924712-G	rs924712	0	924712	intron_variant	FALSE	0.579	4e-6	5.3979400086720375	(EA)	0.0291	[0.017-0.041] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.579	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr17:44252468-A	chr17:44252468	0	NA	NA	TRUE	0.182	7e-13	12.154901959985743	(EA)	0.0605	[0.044-0.077] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.182	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr4:106507402-?	chr4:106507402	0	NA	NA	TRUE	0.0752	2e-6	5.698970004336019	(EA)	0.07	[0.041-0.099] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0752	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr5:49484480-G	chr5:49484480	0	NA	NA	TRUE	0.1506	4e-9	8.397940008672037	(EA)	0.0664	[0.044-0.089] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.1506	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr5:58680596-G	chr5:58680596	0	NA	NA	TRUE	0.0444	1e-7	7	(EA)	0.1061	[0.067-0.145] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0444	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr9:136151579-T	chr9:136151579	0	NA	NA	TRUE	0.2027	1e-8	8	(EA)	0.0446	[0.029-0.06] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.2027	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	8q24.21	8	127359926	NR	CASC8, POU5F1B, PCAT1	NA	NA	ENSG00000246228, ENSG00000212993, ENSG00000253438	NA	NA	rs10096351-G	rs10096351	0	10096351	intron_variant	FALSE	0.5441	2e-64	63.69897000433602	(EA)	0.1055	[0.093-0.118] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.5441	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	10q26.13	10	121568362	NR	FGFR2	NA	NA	ENSG00000066468	NA	NA	rs10510097-T	rs10510097	0	10510097	intron_variant	FALSE	0.1104	2e-58	57.69897000433602	(EA)	0.1546	[0.14-0.17] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.1104	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	1p34.1	1	45688904	NR	TMEM69	NA	NA	ENSG00000159596	NA	NA	rs10683143-A	rs10683143	0	10683143	intron_variant	FALSE	0.4739	2e-6	5.698970004336019	(EA)	0.0319	[0.019-0.045] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.4739	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	11p15.1	11	18642694	NR	SPTY2D1 - SRSF3P1	ENSG00000179119	ENSG00000257043	NA	7903	22356	rs10832963-G	rs10832963	0	10832963	intergenic_variant	TRUE	0.7217	9e-6	5.045757490560675	(EA)	0.0331	[0.019-0.048] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.7217	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	1p12	1	118488075	NR	NA	NA	NA	NA	NA	NA	rs10923574-C	rs10923574	0	10923574	regulatory_region_variant	TRUE	0.3321	4e-7	6.3979400086720375	(EA)	0.0344	[0.021-0.048] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.3321	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	5q23.3	5	128098106	NR	SLC12A2	NA	NA	ENSG00000064651	NA	NA	rs1112956-G	rs1112956	0	1112956	intron_variant	FALSE	0.7711	9e-6	5.045757490560675	(EA)	0.0328	[0.018-0.047] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.7711	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	10p11.1	10	38856846	NR	NA	NA	NA	NA	NA	NA	rs11146838-T	rs11146838	0	11146838	intergenic_variant	TRUE	0.4416	1e-6	6	(EA)	0.0312	[0.019-0.044] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.4416	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	17q11.2	17	30560116	NR	TBC1D29P	NA	NA	ENSG00000266733	NA	NA	rs111780165-A	rs111780165	0	111780165	splice_acceptor_variant	FALSE	0.0706	8e-8	7.096910013008056	(EA)	0.067	[0.043-0.092] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0706	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	2q33.1	2	201003582	NR	FAM126B	NA	NA	ENSG00000155744	NA	NA	rs112257290-A	rs112257290	0	112257290	intron_variant	FALSE	0.058	2e-7	6.698970004336019	(EA)	0.07	[0.044-0.096] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.058	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	5q33.3	5	159008453	NR	EBF1	NA	NA	ENSG00000164330	NA	NA	rs11288072-C	rs11288072	0	11288072	intron_variant	FALSE	0.3116	3e-13	12.522878745280337	(EA)	0.0501	[0.037-0.064] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.3116	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	8p11.23	8	37106253	NR	SMARCE1P4 - NA	ENSG00000253650	NA	NA	10863	NA	rs113167076-A	rs113167076	0	113167076	intergenic_variant	TRUE	0.0228	9e-7	6.045757490560675	(EA)	0.1213	[0.073-0.17] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0228	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	1p34.2	1	42592453	NR	CCDC30	NA	NA	ENSG00000186409	NA	NA	rs113319441-T	rs113319441	0	113319441	3_prime_UTR_variant	FALSE	0.0308	6e-6	5.221848749616356	(EA)	0.0908	[0.051-0.13] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0308	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	8p12	8	36450915	NR	NA	NA	NA	NA	NA	NA	rs113687142-T	rs113687142	0	113687142	intron_variant	TRUE	0.0149	2e-6	5.698970004336019	(EA)	0.1493	[0.089-0.21] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.0149	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	11q24.1	11	123095918	NR	CLMP	NA	NA	ENSG00000166250	NA	NA	rs7121616-G	rs7121616	0	7121616	intron_variant	FALSE	0.2854	7e-6	5.154901959985743	(EA)	0.0314	[0.018-0.045] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.2854	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	14q13.3	14	36667340	NR	PAX9	NA	NA	ENSG00000198807	NA	NA	rs7149262-A	rs7149262	0	7149262	intron_variant	FALSE	0.2113	2e-21	20.69897000433602	(EA)	0.0724	[0.058-0.087] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.2113	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	2p16.1	2	60408219	NR	MIR4432HG	NA	NA	ENSG00000228590	NA	NA	rs72001329-C	rs72001329	1	55975914	intron_variant	FALSE	0.4786	3e-6	5.522878745280337	(EA)	0.0312	[0.018-0.044] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.4786	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	19p13.11	19	19684648	NR	ZNF101 - ZNF14	ENSG00000181896	ENSG00000105708	NA	1139	25824	rs72396995-T	rs72396995	0	72396995	intergenic_variant	TRUE	0.2556	1e-7	7	(EA)	0.0383	[0.024-0.052] unit increase	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.2556	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	19p13.11	19	18422832	NR	SSBP4	NA	NA	ENSG00000130511	NA	NA	rs7258465-C	rs7258465	0	7258465	intron_variant	FALSE	0.3436	3e-28	27.522878745280337	(EA)	0.0725	[0.06-0.085] unit decrease	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.3436	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q23	3	141402972	ZBTB38	ZBTB38	NA	NA	ENSG00000177311	NA	NA	rs2871960-?	rs2871960	0	2871960	5_prime_UTR_variant	FALSE	0.44120000000000004	3e-10	9.522878745280337	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.44120000000000004	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q25.31	3	157080505	LEKR1	LEKR1 - LINC00880	ENSG00000197980	ENSG00000243629	NA	34376	1162	rs1482852-?	rs1482852	0	1482852	intergenic_variant	TRUE	0.5944	2e-13	12.698970004336019	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5944	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q26.31	3	172204265	FNDC3B	FNDC3B	NA	NA	ENSG00000075420	NA	NA	rs12493901-?	rs12493901	0	12493901	intron_variant	FALSE	0.512	3e-10	9.522878745280337	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.512	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4q13.3	4	72611184	ADAMTS3	ADAMTS3 - NA	ENSG00000156140	NA	NA	41963	NA	rs16848284-?	rs16848284	0	16848284	intergenic_variant	TRUE	0.4458	4e-8	7.3979400086720375	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.4458	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4q21.21	4	81228677	PRKG2	PRKG2 - NA	ENSG00000138669	NA	NA	13455	NA	rs710841-?	rs710841	0	710841	intergenic_variant	TRUE	0.2519	2e-9	8.698970004336019	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2519	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4q31.21	4	144653692	HHIP	HHIP-AS1, HHIP	NA	NA	ENSG00000248890, ENSG00000164161	NA	NA	rs1812175-?	rs1812175	0	1812175	intron_variant	FALSE	0.8336	3e-9	8.522878745280337	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.8336	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5p13.3	5	32753566	NPR3	NPR3	NA	NA	ENSG00000113389	NA	NA	rs2062708-?	rs2062708	0	2062708	intron_variant	FALSE	0.16169999999999995	7e-8	7.154901959985743	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.16169999999999995	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q11.2	5	53680995	NDUFS4	NDUFS4	NA	NA	ENSG00000164258	NA	NA	rs2637030-?	rs2637030	0	2637030	intron_variant	FALSE	0.37460000000000004	1e-7	7	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.37460000000000004	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q11.2	5	56560548	MAP3K1	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs3843467-?	rs3843467	0	3843467	intron_variant	FALSE	0.1943	3e-9	8.522878745280337	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.1943	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q14.3	5	89450588	MEF2C	MEF2C-AS1	NA	NA	ENSG00000248309	NA	NA	rs6892330-?	rs6892330	0	6892330	intron_variant	FALSE	0.3585	8e-8	7.096910013008056	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3585	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q35.1	5	171856465	FBXW11	SMIM23 - FBXW11	ENSG00000185662	ENSG00000072803	NA	60339	5084	rs4868126-?	rs4868126	0	4868126	regulatory_region_variant	TRUE	0.6084	6e-9	8.221848749616356	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6084	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q35.3	5	177100576	FGFR4	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-?	rs6556301	0	6556301	intergenic_variant	TRUE	0.3576	7e-15	14.154901959985743	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3576	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q35.3	5	177299634	NSD1	NSD1	NA	NA	ENSG00000165671	NA	NA	rs3088050-?	rs3088050	0	3088050	3_prime_UTR_variant	FALSE	0.2143	6e-12	11.221848749616356	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2143	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p22.2	6	26200449	HIST1H2BF	H2BC7	NA	NA	ENSG00000277224	NA	NA	rs806794-?	rs806794	0	806794	3_prime_UTR_variant	FALSE	0.6986	1e-11	11	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6986	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.32	6	32606394	HLA-DRB1	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735	NA	16546	21785	rs615672-?	rs615672	0	615672	intron_variant	TRUE	0.6531	2e-7	6.698970004336019	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6531	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.31	6	34231315	CYCSL1, HMGA1	CYCSP55 - HMGA1	ENSG00000214810	ENSG00000137309	NA	11249	5558	rs2780226-?	rs2780226	0	2780226	regulatory_region_variant	TRUE	0.0816	5e-12	11.301029995663981	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.0816	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.1	6	43796814	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	10327	48064	rs1358980-?	rs1358980	0	1358980	regulatory_region_variant	TRUE	0.4743	2e-16	15.698970004336019	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.4743	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q14.1	6	75529546	FILIP1	RPL26P20 - H3P27	ENSG00000219722	ENSG00000220730	NA	29410	56576	rs13192994-?	rs13192994	0	13192994	intergenic_variant	TRUE	0.14490000000000003	7e-9	8.154901959985743	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.14490000000000003	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q16.3	6	104916546	HACE1	LIN28B-AS1	NA	NA	ENSG00000203809	NA	NA	rs11156429-?	rs11156429	0	11156429	intron_variant	FALSE	0.4566	3e-15	14.522878745280337	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.4566	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q22.33	6	127127104	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs1936807-?	rs1936807	0	1936807	intron_variant	FALSE	0.5103	1e-9	9	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5103	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q24.2	6	142382740	GPR126	ADGRG6	NA	NA	ENSG00000112414	NA	NA	rs4896582-?	rs4896582	0	4896582	intron_variant	FALSE	0.6960999999999999	3e-13	12.522878745280337	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6960999999999999	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p22.3	7	2762169	AMZ1	GNA12, AMZ1	NA	NA	ENSG00000146535, ENSG00000174945	NA	NA	rs798489-?	rs798489	0	798489	splice_donor_variant	FALSE	0.7105	7e-7	6.154901959985743	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7105	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p21.1	7	20391962	ITGB8	ITGB8	NA	NA	ENSG00000105855	NA	NA	rs10231365-?	rs10231365	0	10231365	intron_variant	FALSE	0.5025	2e-8	7.698970004336019	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5025	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	25831489	UBA52P1	NA	NA	NA	NA	NA	NA	rs1055144-?	rs1055144	0	1055144	non_coding_transcript_exon_variant	TRUE	0.1983	1e-15	15	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.1983	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	27184152	HOXA11	HOXA11	NA	NA	ENSG00000005073	NA	NA	rs7801581-?	rs7801581	0	7801581	intron_variant	FALSE	0.2445	2e-7	6.698970004336019	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2445	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2p15	2	62296430	intergenic	RN7SL51P - RN7SL18P	ENSG00000239958	ENSG00000241625	NA	33759	194748	rs4672497-G	rs4672497	0	4672497	TF_binding_site_variant	TRUE	0.2212	8e-10	9.096910013008056	NA	0.02657948	[0.018-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2212	NA	0.02657948
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q11.2	2	100145754	AFF3	AFF3	NA	NA	ENSG00000144218	NA	NA	rs368755101-A	rs368755101	0	368755101	intron_variant	FALSE	0.3619	2e-12	11.698970004336019	NA	0.02618013	[0.019-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.3619	NA	0.02618013
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q13	2	110852366	ACOXL	ACOXL	NA	NA	ENSG00000153093	NA	NA	rs10197140-C	rs10197140	0	10197140	intron_variant	FALSE	0.339	8e-20	19.096910013008056	NA	0.03432007	[0.027-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.339	NA	0.03432007
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q13	2	110979246	ACOXL	ACOXL	NA	NA	ENSG00000153093	NA	NA	rs56088557-G	rs56088557	0	56088557	intron_variant	FALSE	0.2063	3e-15	14.522878745280337	NA	0.03490228	[0.026-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2063	NA	0.03490228
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q13	2	111380587	MIR4435-1HG	MIR4435-2HG	NA	NA	ENSG00000172965	NA	NA	rs78124867-T	rs78124867	0	78124867	intron_variant	FALSE	0.1916	1e-36	36	NA	0.06639744	[0.056-0.077] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1916	NA	0.06639744
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q13	2	111410354	MIR4435-1HG	MIR4435-2HG	NA	NA	ENSG00000172965	NA	NA	rs62160676-C	rs62160676	0	62160676	intron_variant	FALSE	0.2974	4e-50	49.39794000867204	NA	0.0582557	[0.051-0.066] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2974	NA	0.0582557
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q13	2	111521758	intergenic	SOCAR, MIR4435-2HG	NA	NA	ENSG00000240350, ENSG00000172965	NA	NA	rs62162297-T	rs62162297	0	62162297	intron_variant	FALSE	0.8656	2e-28	27.69897000433602	NA	0.05771682	[0.047-0.068] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.8656	NA	0.05771682
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q14.1	2	113199604	PSD4	PSD4	NA	NA	ENSG00000125637	NA	NA	rs5833486-TA	rs5833486	0	5833486	intron_variant	FALSE	0.2229	4e-19	18.397940008672037	NA	0.03883427	[0.03-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2229	NA	0.03883427
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q14.2	2	121238062	TFCP2L1	TFCP2L1	NA	NA	ENSG00000115112	NA	NA	rs11689538-C	rs11689538	0	11689538	intron_variant	FALSE	0.1401	6e-11	10.221848749616356	NA	0.03368555	[0.024-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1401	NA	0.03368555
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q31.3	2	181075915	UBE2E3	UBE2E3	NA	NA	ENSG00000170035	NA	NA	rs10191559-A	rs10191559	0	10191559	intron_variant	FALSE	0.6988	4e-10	9.397940008672037	NA	0.02426728	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6988	NA	0.02426728
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q32.2	2	189568259	SLC40A1	SLC40A1	NA	NA	ENSG00000138449	NA	NA	rs112257498-T	rs112257498	0	112257498	intron_variant	FALSE	0.6135	6e-9	8.221848749616356	NA	0.0213889	[0.014-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6135	NA	0.0213889
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q33.3	2	207134989	KLF7	KLF7	NA	NA	ENSG00000118263	NA	NA	rs7583880-A	rs7583880	0	7583880	intron_variant	FALSE	0.6915	6e-9	8.221848749616356	NA	0.02247999	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6915	NA	0.02247999
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	2q35	2	218414374	VIL1	CTDSP1 - VIL1	ENSG00000144579	ENSG00000127831	NA	8433	4747	rs7607369-G	rs7607369	0	7607369	intergenic_variant	TRUE	0.5673	1e-20	20	NA	0.03334282	[0.026-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5673	NA	0.03334282
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3p24.3	3	16891490	PLCL2	PLCL2, PLCL2	NA	NA	ENSG00000154822, ENSG00000284017	NA	NA	rs73146904-A	rs73146904	0	73146904	intron_variant	FALSE	0.0737	1e-12	12	NA	0.04857125	[0.035-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0737	NA	0.04857125
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3p24.2	3	24293021	THRB	THRB	NA	NA	ENSG00000151090	NA	NA	rs113700287-TTTTG	rs113700287	0	113700287	intron_variant	FALSE	0.6712	2e-30	29.69897000433602	NA	0.04382223	[0.036-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6712	NA	0.04382223
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3p21.1	3	52799789	ITIH3	ITIH3	NA	NA	ENSG00000162267	NA	NA	rs3617-A	rs3617	0	3617	missense_variant	FALSE	0.4523	2e-9	8.698970004336019	NA	0.02130175	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4523	NA	0.02130175
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3p14.3	3	56710234	intergenic	TASOR - ARHGEF3	ENSG00000163946	ENSG00000163947	NA	26969	17184	rs149804345-AAAAAAC	rs149804345	0	149804345	intergenic_variant	TRUE	0.3097	1e-20	20	NA	0.03618318	[0.029-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.3097	NA	0.03618318
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3p14.3	3	58388302	PXK	PXK	NA	NA	ENSG00000168297	NA	NA	rs7610312-G	rs7610312	0	7610312	intron_variant	FALSE	0.3704	5e-9	8.301029995663981	NA	0.02158849	[0.014-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.3704	NA	0.02158849
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3p13	3	69756466	MITF	MITF	NA	NA	ENSG00000187098	NA	NA	rs34858804-A	rs34858804	0	34858804	intron_variant	FALSE	0.4259	1e-12	12	NA	0.02584589	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4259	NA	0.02584589
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3p13	3	71207158	FOXP1	FOXP1	NA	NA	ENSG00000114861	NA	NA	rs17699658-T	rs17699658	0	17699658	intron_variant	FALSE	0.223	7e-14	13.154901959985743	NA	0.0325114	[0.024-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.223	NA	0.0325114
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3q23	3	141431184	ZBTB38	ZBTB38	NA	NA	ENSG00000177311	NA	NA	rs7625643-G	rs7625643	0	7625643	intron_variant	FALSE	0.4457	8e-21	20.096910013008056	NA	0.03400545	[0.027-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4457	NA	0.03400545
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	NA	NA	NA	ATR	NA	NA	NA	NA	NA	NA	chr3:142295743-ATC	chr3:142295743	0	NA	NA	TRUE	0.5873	9e-25	24.045757490560675	NA	0.03709958	[0.03-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5873	NA	0.03709958
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3q26.2	3	169399217	MECOM	MECOM	NA	NA	ENSG00000085276	NA	NA	rs9290366-G	rs9290366	0	9290366	intron_variant	FALSE	0.5428	3e-11	10.522878745280337	NA	0.0236921	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5428	NA	0.0236921
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3q29	3	194956076	intergenic	NA	NA	NA	NA	NA	NA	rs35060063-A	rs35060063	0	35060063	intergenic_variant	TRUE	0.5023	2e-9	8.698970004336019	NA	0.02136169	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5023	NA	0.02136169
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3q29	3	196103509	intergenic	TFRC - LINC00885	ENSG00000072274	ENSG00000224652	NA	21413	39016	rs74203182-T	rs74203182	0	74203182	regulatory_region_variant	TRUE	0.6959	3e-35	34.52287874528034	NA	0.04861946	[0.041-0.056] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6959	NA	0.04861946
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118988874	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs1106529-A	rs1106529	0	1106529	intron_variant	FALSE	0.7439	4e-9	8.397940008672037	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.7439	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	119031964	TBX15, WARS2	WARS2	NA	NA	ENSG00000116874	NA	NA	rs2645294-T	rs2645294	0	2645294	3_prime_UTR_variant	FALSE	0.5659	1e-9	9	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.5659	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q24.2	1	170403362	GORAB	HAUS4P1 - GORAB-AS1	ENSG00000226967	ENSG00000231407	NA	32995	57091	rs10919388-A	rs10919388	0	10919388	intergenic_variant	TRUE	0.28	2e-6	5.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.28	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q24.3	1	172383850	DNM3, PIGC	PIGC, DNM3	NA	NA	ENSG00000135845, ENSG00000197959	NA	NA	rs714515-A	rs714515	0	714515	intron_variant	FALSE	0.5576	9e-6	5.045757490560675	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.5576	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q41	1	219580167	LYPLAL1	NA - ZC3H11B	NA	ENSG00000215817	NA	NA	27843	rs2820443-T	rs2820443	0	2820443	regulatory_region_variant	TRUE	0.7255	6e-11	10.221848749616356	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.7255	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p14.1	3	64732582	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs2371767-C	rs2371767	0	2371767	intron_variant	FALSE	0.3027	6e-13	12.221848749616356	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.3027	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q35.3	5	177100576	FGFR4	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-T	rs6556301	0	6556301	intergenic_variant	TRUE	0.3609	7e-6	5.154901959985743	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.3609	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.32	6	32413959	BTNL2	TSBP1-AS1 - HLA-DRA	ENSG00000225914	ENSG00000234794	NA	6196	25919	rs7759742-A	rs7759742	0	7759742	regulatory_region_variant	TRUE	0.5117	1e-8	8	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.5117	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.1	6	43796814	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	10327	48064	rs1358980-T	rs1358980	0	1358980	regulatory_region_variant	TRUE	0.4685	5e-7	6.301029995663981	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.4685	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q22.33	6	127130971	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs1936805-T	rs1936805	0	1936805	intron_variant	FALSE	0.518	2e-12	11.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.518	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8q13.3	8	71601993	MSC	EYA1 - NA	ENSG00000104313	NA	NA	9968	NA	rs12679556-T	rs12679556	0	12679556	intergenic_variant	TRUE	0.7074	5e-8	7.301029995663981	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.7074	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12p11.23	12	26318431	ITPR2, SSPN	SSPN - ITPR2	ENSG00000123096	ENSG00000123104	NA	19141	16921	rs10842707-T	rs10842707	0	10842707	intron_variant	TRUE	0.2246	5e-6	5.301029995663981	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.2246	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q13.13	12	53948900	HOXC13	HOXC13 - HOXC12	ENSG00000123364	ENSG00000123407	NA	2356	6003	rs1443512-A	rs1443512	0	1443512	regulatory_region_variant	TRUE	0.2662	5e-7	6.301029995663981	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.2662	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q13.13	12	53955989	HOXC12	HOXC12	NA	NA	ENSG00000123407	NA	NA	rs10783615-A	rs10783615	0	10783615	intron_variant	FALSE	0.7973	2e-10	9.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.7973	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q24.31	12	123955563	CCDC92	CCDC92	NA	NA	ENSG00000119242	NA	NA	rs4765219-A	rs4765219	0	4765219	intron_variant	FALSE	0.3303	2e-7	6.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.3303	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q13.3	15	31416060	KLF13	KLF13, KLF13	NA	NA	ENSG00000275746, ENSG00000169926	NA	NA	rs8042543-T	rs8042543	0	8042543	intron_variant	FALSE	0.2071	7e-6	5.154901959985743	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.2071	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	20q13.12	20	46930192	EYA2	EYA2	NA	NA	ENSG00000064655	NA	NA	rs6090583-A	rs6090583	0	6090583	intron_variant	FALSE	0.495	3e-7	6.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.495	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q24.2	1	170403362	GORAB	HAUS4P1 - GORAB-AS1	ENSG00000226967	ENSG00000231407	NA	32995	57091	rs10919388-A	rs10919388	0	10919388	intergenic_variant	TRUE	0.28	7e-6	5.154901959985743	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.28	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q24.3	1	172383850	DNM3, PIGC	PIGC, DNM3	NA	NA	ENSG00000135845, ENSG00000197959	NA	NA	rs714515-A	rs714515	0	714515	intron_variant	FALSE	0.5576	7e-6	5.154901959985743	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.5576	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q41	1	219580167	LYPLAL1	NA - ZC3H11B	NA	ENSG00000215817	NA	NA	27843	rs2820443-T	rs2820443	0	2820443	regulatory_region_variant	TRUE	0.7255	2e-17	16.69897000433602	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.7255	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2q24.3	2	164656581	GRB14, COBLL1	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs10195252-T	rs10195252	0	10195252	intron_variant	FALSE	0.575	3e-6	5.522878745280337	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.575	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2q24.3	2	164672114	COBLL1	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs1128249-T	rs1128249	0	1128249	intron_variant	FALSE	0.4179	2e-9	8.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.4179	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2q24.3	2	164701742	COBLL1	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs12692738-T	rs12692738	0	12692738	intron_variant	FALSE	0.7339	4e-7	6.3979400086720375	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.7339	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p25.2	3	12447843	PPARG	PPARG - TSEN2	ENSG00000132170	ENSG00000154743	NA	13487	36578	rs17819328-T	rs17819328	0	17819328	intergenic_variant	TRUE	0.5694	6e-6	5.221848749616356	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.5694	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p14.1	3	64732582	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs2371767-C	rs2371767	0	2371767	intron_variant	FALSE	0.3027	1e-15	15	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.3027	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	4q22.1	4	88791970	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs9991328-T	rs9991328	0	9991328	intron_variant	FALSE	0.498	1e-7	7	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.498	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.1	6	43796814	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	10327	48064	rs1358980-T	rs1358980	0	1358980	regulatory_region_variant	TRUE	0.4685	3e-8	7.522878745280337	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.4685	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q22.33	6	127130971	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs1936805-T	rs1936805	0	1936805	intron_variant	FALSE	0.518	9e-11	10.045757490560675	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.518	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8q13.3	8	71601993	MSC	EYA1 - NA	ENSG00000104313	NA	NA	9968	NA	rs12679556-T	rs12679556	0	12679556	intergenic_variant	TRUE	0.7074	8e-8	7.096910013008056	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.7074	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q13.13	12	53948900	HOXC13	HOXC13 - HOXC12	ENSG00000123364	ENSG00000123407	NA	2356	6003	rs1443512-A	rs1443512	0	1443512	regulatory_region_variant	TRUE	0.2662	5e-7	6.301029995663981	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.2662	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q13.13	12	53955989	HOXC12	HOXC12	NA	NA	ENSG00000123407	NA	NA	rs10783615-A	rs10783615	0	10783615	intron_variant	FALSE	0.7973	4e-9	8.397940008672037	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.7973	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q24.31	12	123955563	CCDC92	CCDC92	NA	NA	ENSG00000119242	NA	NA	rs4765219-A	rs4765219	0	4765219	intron_variant	FALSE	0.3303	1e-7	7	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.3303	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8p21.2	8	23745811	NKX2, 6	NKX2-6 - STC1	ENSG00000180053	ENSG00000159167	NA	39055	96118	rs7830933-A	rs7830933	0	7830933	intron_variant	TRUE	0.7569	2e-6	5.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.7569	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	119031964	TBX15, WARS2	WARS2	NA	NA	ENSG00000116874	NA	NA	rs2645294-T	rs2645294	0	2645294	3_prime_UTR_variant	FALSE	0.5659	4e-6	5.3979400086720375	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.5659	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q11.2	5	56510924	ANKRD55	RPL26P19 - C5orf67	ENSG00000226221	ENSG00000225940	NA	5852	643	rs459193-A	rs459193	0	459193	intergenic_variant	TRUE	0.2796	2e-9	8.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.2796	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q35.3	5	177100576	FGFR4	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-T	rs6556301	0	6556301	intergenic_variant	TRUE	0.3609	5e-6	5.301029995663981	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.3609	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q13.13	12	54034227	HOXC4, HOXC6	HOXC4, HOXC5	NA	NA	ENSG00000198353, ENSG00000172789	NA	NA	rs2071449-A	rs2071449	0	2071449	intron_variant	FALSE	0.3602	6e-6	5.221848749616356	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.3602	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	19p13.11	19	18278325	JUND	IQCN - JUND	ENSG00000130518	ENSG00000130522	NA	3816	1369	rs12608504-A	rs12608504	0	12608504	regulatory_region_variant	TRUE	0.3583	2e-6	5.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.3583	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q11.2	5	56510924	MAP3K1	RPL26P19 - C5orf67	ENSG00000226221	ENSG00000225940	NA	5852	643	rs459193-A	rs459193	0	459193	intergenic_variant	TRUE	0.264	2e-17	16.69897000433602	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.264	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8q24.13	8	125465736	TRIB1	TRIB1 - NA	ENSG00000173334	NA	NA	27333	NA	rs2001945-G	rs2001945	0	2001945	regulatory_region_variant	TRUE	0.484	2e-6	5.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.484	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q13.13	12	54034227	HOXC4, HOXC6	HOXC4, HOXC5	NA	NA	ENSG00000198353, ENSG00000172789	NA	NA	rs2071449-A	rs2071449	0	2071449	intron_variant	FALSE	0.365	3e-9	8.522878745280337	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.365	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	19p13.11	19	18278325	JUND	IQCN - JUND	ENSG00000130518	ENSG00000130522	NA	3816	1369	rs12608504-A	rs12608504	0	12608504	regulatory_region_variant	TRUE	0.362	2e-8	7.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004507	Genome-wide genotyping array	0.362	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2p23.3	2	24927427	ADCY3	ADCY3 - DNAJC27	ENSG00000138031	ENSG00000115137	NA	7190	16209	rs10182181-A	rs10182181	0	10182181	intergenic_variant	TRUE	0.5182	2e-12	11.698970004336019	(women)	0.0329	[0.024-0.042] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.5182	NA	0.0329
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2p23.3	2	24927427	ADCY3	ADCY3 - DNAJC27	ENSG00000138031	ENSG00000115137	NA	7190	16209	rs10182181-A	rs10182181	0	10182181	intergenic_variant	TRUE	0.5182	7e-19	18.154901959985743	NA	0.0301	[0.023-0.037] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.5182	NA	0.0301
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2p23.3	2	24927427	ADCY3	ADCY3 - DNAJC27	ENSG00000138031	ENSG00000115137	NA	7190	16209	rs10182181-A	rs10182181	0	10182181	intergenic_variant	TRUE	0.5182	5e-8	7.301029995663981	(men)	0.026	[0.017-0.035] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.5182	NA	0.026
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q24.1	15	72801650	ADPGK	ADPGK-AS1 - NPM1P42	ENSG00000260898	ENSG00000259259	NA	3451	97749	rs7164727-T	rs7164727	0	7164727	intergenic_variant	TRUE	0.6483	2e-7	6.698970004336019	NA	0.0179	[0.011-0.025] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.6483	NA	0.0179
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q21.3	7	95540202	ASB4	ASB4	NA	NA	ENSG00000005981	NA	NA	rs6465468-T	rs6465468	0	6465468	3_prime_UTR_variant	FALSE	0.2957	8e-7	6.096910013008056	NA	0.0183	[0.011-0.026] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.2957	NA	0.0183
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q21.3	7	95540202	ASB4	ASB4	NA	NA	ENSG00000005981	NA	NA	rs6465468-T	rs6465468	0	6465468	3_prime_UTR_variant	FALSE	0.2957	6e-7	6.221848749616356	(women)	0.0237	[0.014-0.033] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.2957	NA	0.0237
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16p11.2	16	28878165	ATP2A1	SH2B1 - ATP2A1	ENSG00000178188	ENSG00000196296	NA	3953	240	rs3888190-A	rs3888190	0	3888190	intron_variant	TRUE	0.3835	6e-10	9.221848749616356	(women)	0.0262	[0.018-0.034] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.3835	NA	0.0262
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16p11.2	16	28878165	ATP2A1	SH2B1 - ATP2A1	ENSG00000178188	ENSG00000196296	NA	3953	240	rs3888190-A	rs3888190	0	3888190	intron_variant	TRUE	0.3835	2e-18	17.69897000433602	NA	0.029	[0.023-0.035] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.3835	NA	0.029
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16p11.2	16	28878165	ATP2A1	SH2B1 - ATP2A1	ENSG00000178188	ENSG00000196296	NA	3953	240	rs3888190-A	rs3888190	0	3888190	intron_variant	TRUE	0.3835	6e-11	10.221848749616356	(men)	0.0319	[0.022-0.042] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.3835	NA	0.0319
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	11p14.1	11	27662970	BDNF	BDNF, BDNF-AS	NA	NA	ENSG00000176697, ENSG00000245573	NA	NA	rs11030104-A	rs11030104	0	11030104	intron_variant	FALSE	0.7872	5e-11	10.301029995663981	(men)	0.0375	[0.026-0.049] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.7872	NA	0.0375
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	11p14.1	11	27662970	BDNF	BDNF, BDNF-AS	NA	NA	ENSG00000176697, ENSG00000245573	NA	NA	rs11030104-A	rs11030104	0	11030104	intron_variant	FALSE	0.7872	5e-22	21.30102999566398	NA	0.0403	[0.032-0.049] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.7872	NA	0.0403
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	11p14.1	11	27662970	BDNF	BDNF, BDNF-AS	NA	NA	ENSG00000176697, ENSG00000245573	NA	NA	rs11030104-A	rs11030104	0	11030104	intron_variant	FALSE	0.7872	1e-13	13	(women)	0.0426	[0.031-0.054] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.7872	NA	0.0426
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	18q11.2	18	23524924	C18orf8	RMC1, NPC1	NA	NA	ENSG00000141452, ENSG00000141458	NA	NA	rs1808579-T	rs1808579	0	1808579	intron_variant	FALSE	0.4656	1e-6	6	(women)	0.0216	[0.013-0.03] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4656	NA	0.0216
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	18q11.2	18	23524924	C18orf8	RMC1, NPC1	NA	NA	ENSG00000141452, ENSG00000141458	NA	NA	rs1808579-T	rs1808579	0	1808579	intron_variant	FALSE	0.4656	8e-6	5.096910013008056	NA	0.0152	[0.0085-0.0219] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4656	NA	0.0152
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q13.3	5	75719417	C5orf37	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078	NA	1969	33153	rs2112347-T	rs2112347	0	2112347	intergenic_variant	TRUE	0.6128	5e-8	7.301029995663981	(women)	0.0233	[0.015-0.032] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.6128	NA	0.0233
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q13.3	5	75719417	C5orf37	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078	NA	1969	33153	rs2112347-T	rs2112347	0	2112347	intergenic_variant	TRUE	0.6128	1e-13	13	NA	0.0242	[0.018-0.031] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.6128	NA	0.0242
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q13.3	5	75719417	C5orf37	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078	NA	1969	33153	rs2112347-T	rs2112347	0	2112347	intergenic_variant	TRUE	0.6128	4e-7	6.3979400086720375	(men)	0.0243	[0.015-0.034] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.6128	NA	0.0243
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.31	6	34595387	C6orf106	ILRUN	NA	NA	ENSG00000196821	NA	NA	rs205262-A	rs205262	0	205262	intron_variant	FALSE	0.694	3e-7	6.522878745280337	(women)	0.0255	[0.016-0.035] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.694	NA	0.0255
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.31	6	34595387	C6orf106	ILRUN	NA	NA	ENSG00000196821	NA	NA	rs205262-A	rs205262	0	205262	intron_variant	FALSE	0.694	3e-9	8.522878745280337	NA	0.0223	[0.015-0.03] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.694	NA	0.0223
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p12.1	3	85758440	CADM2	CADM2	NA	NA	ENSG00000175161	NA	NA	rs13078960-T	rs13078960	0	13078960	intron_variant	FALSE	0.8065	7e-8	7.154901959985743	(women)	0.0293	[0.019-0.04] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.8065	NA	0.0293
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p12.1	3	85758440	CADM2	CADM2	NA	NA	ENSG00000175161	NA	NA	rs13078960-T	rs13078960	0	13078960	intron_variant	FALSE	0.8065	1e-10	10	NA	0.0261	[0.018-0.034] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.8065	NA	0.0261
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q21.3	7	93568420	CALCR	CALCR	NA	NA	ENSG00000004948	NA	NA	rs9641123-C	rs9641123	0	9641123	intron_variant	FALSE	0.4166	2e-6	5.698970004336019	(women)	0.0238	[0.014-0.034] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4166	NA	0.0238
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q21.3	7	93568420	CALCR	CALCR	NA	NA	ENSG00000004948	NA	NA	rs9641123-C	rs9641123	0	9641123	intron_variant	FALSE	0.4166	1e-11	11	NA	0.0258	[0.018-0.033] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4166	NA	0.0258
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q21.3	7	93568420	CALCR	CALCR	NA	NA	ENSG00000004948	NA	NA	rs9641123-C	rs9641123	0	9641123	intron_variant	FALSE	0.4166	3e-7	6.522878745280337	(men)	0.029	[0.018-0.04] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4166	NA	0.029
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q11.23	7	76978826	CCDC140	DTX2P1, DTX2P1-UPK3BP1-PMS2P11	NA	NA	ENSG00000186704, ENSG00000265479	NA	NA	rs2245368-T	rs2245368	0	2245368	non_coding_transcript_exon_variant	FALSE	0.8036	6e-8	7.221848749616356	(women)	0.0378	[0.024-0.052] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.8036	NA	0.0378
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q11.23	7	76978826	CCDC140	DTX2P1, DTX2P1-UPK3BP1-PMS2P11	NA	NA	ENSG00000186704, ENSG00000265479	NA	NA	rs2245368-T	rs2245368	0	2245368	non_coding_transcript_exon_variant	FALSE	0.8036	3e-10	9.522878745280337	NA	0.0331	[0.023-0.043] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.8036	NA	0.0331
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q26.33	3	180723384	CCDC39	CCDC39	NA	NA	ENSG00000145075	NA	NA	rs13069244-A	rs13069244	0	13069244	intron_variant	FALSE	0.078	6e-10	9.221848749616356	NA	0.031	[0.021-0.041] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.078	NA	0.031
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16p11.2	16	30004016	CCDC95	INO80E	NA	NA	ENSG00000169592	NA	NA	rs4787491-A	rs4787491	0	4787491	non_coding_transcript_exon_variant	FALSE	0.4825	2e-9	8.698970004336019	NA	0.0201	[0.014-0.027] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4825	NA	0.0201
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16p11.2	16	30004016	CCDC95	INO80E	NA	NA	ENSG00000169592	NA	NA	rs4787491-A	rs4787491	0	4787491	non_coding_transcript_exon_variant	FALSE	0.4825	6e-6	5.221848749616356	(women)	0.0198	[0.011-0.028] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4825	NA	0.0198
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2p16.1	2	59078490	CIB4	LINC01122 - NA	ENSG00000233723	NA	NA	14724	NA	rs1016287-T	rs1016287	0	1016287	intron_variant	TRUE	0.2819	8e-8	7.096910013008056	NA	0.0196	[0.012-0.027] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.2819	NA	0.0196
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2p16.1	2	59078490	CIB4	LINC01122 - NA	ENSG00000233723	NA	NA	14724	NA	rs1016287-T	rs1016287	0	1016287	intron_variant	TRUE	0.2819	2e-6	5.698970004336019	(women)	0.0223	[0.013-0.032] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.2819	NA	0.0223
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q21.2	15	51456413	DMXL2	DMXL2	NA	NA	ENSG00000104093	NA	NA	rs3736485-A	rs3736485	0	3736485	non_coding_transcript_exon_variant	FALSE	0.4757	2e-6	5.698970004336019	NA	0.0151	[0.0088-0.0214] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4757	NA	0.0151
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p33	1	50094148	ELAVL4	ELAVL4	NA	NA	ENSG00000162374	NA	NA	rs11583200-T	rs11583200	0	11583200	intron_variant	FALSE	0.5794	2e-6	5.698970004336019	(women)	0.0222	[0.013-0.031] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.5794	NA	0.0222
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	119004219	TBX15	TBX15 - WARS2	ENSG00000092607	ENSG00000116874	NA	14663	26997	rs10923724-?	rs10923724	0	10923724	intergenic_variant	TRUE	0.5653	1e-10	10	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5653	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q21.2	1	149934520	MTMR11	MTMR11	NA	NA	ENSG00000014914	NA	NA	rs11205303-?	rs11205303	0	11205303	missense_variant	FALSE	0.37529999999999997	5e-8	7.301029995663981	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.37529999999999997	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.3	1	184054395	TSEN15	TSEN15	NA	NA	ENSG00000198860	NA	NA	rs1046934-?	rs1046934	0	1046934	missense_variant	FALSE	0.3497	9e-6	5.045757490560675	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3497	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q41	1	218432267	TGFB2, LYPLAL1	TGFB2	NA	NA	ENSG00000092969	NA	NA	rs10482795-?	rs10482795	0	10482795	intron_variant	FALSE	0.3004	3e-7	6.522878745280337	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3004	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p23.3	2	25260101	DNMT3A	DNMT3A	NA	NA	ENSG00000119772	NA	NA	rs11694842-?	rs11694842	0	11694842	intron_variant	FALSE	0.6728	2e-7	6.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6728	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p22.3	2	33154196	LTBP1	LTBP1	NA	NA	ENSG00000049323	NA	NA	rs6715793-?	rs6715793	0	6715793	intron_variant	FALSE	0.4932	2e-6	5.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.4932	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p16.1	2	55869757	EFEMP1	EFEMP1	NA	NA	ENSG00000115380	NA	NA	rs3791679-?	rs3791679	0	3791679	intron_variant	FALSE	0.7579	9e-14	13.045757490560675	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7579	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2q36.3	2	226258868	IRS1	NYAP2 - MIR5702	ENSG00000144460	ENSG00000263363	NA	604850	399842	rs2943658-?	rs2943658	0	2943658	intergenic_variant	TRUE	0.3614	3e-8	7.522878745280337	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3614	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2q37.1	2	231939445	NPPC	NPPC - DIS3L2	ENSG00000163273	ENSG00000144535	NA	13049	21800	rs2580821-?	rs2580821	0	2580821	intergenic_variant	TRUE	0.9172	6e-11	10.221848749616356	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.9172	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	2p25.3	2	622827	TMEM18	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	76160	41050	rs2867125-C	rs2867125	0	2867125	intergenic_variant	TRUE	0.8261000000000001	2e-8	7.698970004336019	(EA, men)	0.0635	[0.041-0.086] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.8261000000000001	NA	0.0635
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	3p24.2	3	25068924	LOC100129045, RARB	RNA5SP125 - RARB	ENSG00000201713	ENSG00000077092	NA	43798	105408	rs7619139-A	rs7619139	0	7619139	intron_variant	TRUE	0.5881	6e-7	6.221848749616356	(EA, men)	0.0438	[0.027-0.061] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.5881	NA	0.0438
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	4q24	4	102267552	SLC39A8	SLC39A8	NA	NA	ENSG00000138821	NA	NA	rs13107325-T	rs13107325	0	13107325	missense_variant	FALSE	0.0875	2e-6	5.698970004336019	(EA, men)	0.0868	[0.051-0.122] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.0875	NA	0.0868
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	5q23.2	5	124994829	LOC644659, ZNF608	LINC02240	NA	NA	ENSG00000260192	NA	NA	rs6864049-G	rs6864049	0	6864049	intron_variant	FALSE	0.5327999999999999	2e-6	5.698970004336019	(EA, men)	0.041	[0.024-0.058] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.5327999999999999	NA	0.041
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	16q12.2	16	53784548	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs3751812-T	rs3751812	0	3751812	intron_variant	FALSE	0.4119	2e-19	18.69897000433602	(EA, men)	0.0783	[0.061-0.095] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.4119	NA	0.0783
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	18q21.32	18	60192330	MC4R	RNU4-17P - NA	ENSG00000202468	NA	NA	28623	NA	rs12969709-A	rs12969709	0	12969709	intergenic_variant	TRUE	0.2573	5e-10	9.301029995663981	(EA, men)	0.0613	[0.042-0.081] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.2573	NA	0.0613
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p31.1	1	72371807	KRT8P21, NEGR1	RPL31P12 - NA	ENSG00000227207	NA	NA	69978	NA	rs11209951-T	rs11209951	0	11209951	intron_variant	TRUE	0.6157	2e-7	6.698970004336019	(EA,women)	0.0289	[0.018-0.04] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.6157	NA	0.0289
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p31.1	1	74529541	TNNI3K	FPGT-TNNI3K, TNNI3K	NA	NA	ENSG00000259030, ENSG00000116783	NA	NA	rs7551507-C	rs7551507	0	7551507	intron_variant	FALSE	0.4416	9e-9	8.045757490560675	(EA,women)	0.0305	[0.02-0.041] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.4416	NA	0.0305
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p31.1	1	77998184	DNAJB4	GIPC2, DNAJB4	NA	NA	ENSG00000137960, ENSG00000162616	NA	NA	rs4130548-C	rs4130548	0	4130548	intron_variant	FALSE	0.3548	2e-6	5.698970004336019	(EA,women)	0.0263	[0.016-0.037] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.3548	NA	0.0263
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p31.1	1	78212446	MGC27382	RNFT1P2 - MGC27382	ENSG00000233333	ENSG00000237413	NA	41209	17153	rs12406019-G	rs12406019	0	12406019	intergenic_variant	TRUE	0.44989999999999997	9e-8	7.045757490560675	(EA,women)	0.0284	[0.018-0.039] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.44989999999999997	NA	0.0284
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p13.3	1	109612066	GNAT2	GNAT2	NA	NA	ENSG00000134183	NA	NA	rs17024393-C	rs17024393	0	17024393	intron_variant	FALSE	0.03739999999999999	2e-9	8.698970004336019	(EA,women)	0.0906	[0.061-0.12] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.03739999999999999	NA	0.0906
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1q25.2	1	177920345	SEC16B	LINC01741 - SEC16B	ENSG00000236720	ENSG00000120341	NA	208070	3611	rs543874-G	rs543874	0	543874	intergenic_variant	TRUE	0.19289999999999996	2e-19	18.69897000433602	(EA,women)	0.0606	[0.047-0.074] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.19289999999999996	NA	0.0606
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	2p25.3	2	622827	TMEM18	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	76160	41050	rs2867125-C	rs2867125	0	2867125	intergenic_variant	TRUE	0.8244	2e-24	23.69897000433602	(EA,women)	0.0717	[0.058-0.085] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.8244	NA	0.0717
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	2p23.3	2	24927247	ADCY3	ADCY3 - DNAJC27	ENSG00000138031	ENSG00000115137	NA	7010	16389	rs6752378-A	rs6752378	0	6752378	intergenic_variant	TRUE	0.4641	5e-12	11.301029995663981	(EA,women)	0.0374	[0.027-0.048] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.4641	NA	0.0374
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	3p14.2	3	61250788	FHIT	FHIT	NA	NA	ENSG00000189283	NA	NA	rs2365389-C	rs2365389	0	2365389	intron_variant	FALSE	0.5865	2e-6	5.698970004336019	(EA,women)	0.0256	[0.015-0.036] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.5865	NA	0.0256
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	3q27.2	3	186096853	ETV5	ETV5	NA	NA	ENSG00000244405	NA	NA	rs6809651-G	rs6809651	0	6809651	intron_variant	FALSE	0.8694999999999999	1e-10	10	(EA,women)	0.0507	[0.035-0.066] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.8694999999999999	NA	0.0507
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.1	7	28150327	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs1708299-?	rs1708299	0	1708299	intron_variant	FALSE	0.2994	9e-13	12.045757490560675	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2994	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9q22.32	9	95648123	PTCH1	NA	NA	NA	NA	NA	NA	rs10990303-?	rs10990303	0	10990303	intergenic_variant	TRUE	0.2238	5e-10	9.301029995663981	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2238	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9q31.2	9	106163165	TMEM38B	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs7020666-?	rs7020666	0	7020666	intron_variant	FALSE	0.7075	5e-7	6.301029995663981	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7075	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	10q22.3	10	79147390	ZMIZ1	ZMIZ1	NA	NA	ENSG00000108175	NA	NA	rs780159-?	rs780159	0	780159	intron_variant	FALSE	0.5817	5e-8	7.301029995663981	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5817	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	11p15.1	11	17294482	NUCB2	NUCB2	NA	NA	ENSG00000070081	NA	NA	rs1330-?	rs1330	0	1330	intron_variant	FALSE	0.3426	4e-7	6.3979400086720375	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3426	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	11q13.5	11	75565133	SERPINH1	SERPINH1	NA	NA	ENSG00000149257	NA	NA	rs606452-?	rs606452	0	606452	intron_variant	FALSE	0.1447	1e-8	8	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.1447	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12p11.23	12	26300350	ITPR2, SSPN	SSPN - ITPR2	ENSG00000123096	ENSG00000123104	NA	1060	35002	rs718314-?	rs718314	0	718314	intron_variant	TRUE	0.2551	8e-9	8.096910013008056	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2551	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12p11.22	12	28318386	CCDC91	CCDC91	NA	NA	ENSG00000123106	NA	NA	rs10843151-?	rs10843151	0	10843151	intron_variant	FALSE	0.6889000000000001	1e-9	9	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6889000000000001	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q13.13	12	54027692	HOXC4, HOXC5, HOXC6	HOXC4, HOXC6	NA	NA	ENSG00000198353, ENSG00000197757	NA	NA	rs10876528-?	rs10876528	0	10876528	intron_variant	FALSE	0.3597	4e-13	12.397940008672037	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3597	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q24.31	12	123955563	CCDC92	CCDC92	NA	NA	ENSG00000119242	NA	NA	rs4765219-?	rs4765219	0	4765219	intron_variant	FALSE	0.6652	7e-10	9.154901959985743	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6652	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	14q32.12	14	91993614	TRIP11	TRIP11	NA	NA	ENSG00000100815	NA	NA	rs8007661-?	rs8007661	0	8007661	intron_variant	FALSE	0.6098	1e-6	6	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6098	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q24.1	15	73936469	LOXL1	LOXL1	NA	NA	ENSG00000129038	NA	NA	rs4886782-?	rs4886782	0	4886782	intron_variant	FALSE	0.6194	1e-9	9	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6194	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	83845538	ADAMTSL3	ADAMTSL3	NA	NA	ENSG00000156218	NA	NA	rs7162542-?	rs7162542	0	7162542	intron_variant	FALSE	0.5582	1e-25	25	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5582	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	84597563	ZSCAN2	LINC00933 - ZSCAN2	ENSG00000259728	ENSG00000176371	NA	17388	3423	rs7176527-?	rs7176527	0	7176527	intergenic_variant	TRUE	0.8071	3e-8	7.522878745280337	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.8071	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q26.1	15	88871064	ACAN	ACAN	NA	NA	ENSG00000157766	NA	NA	rs1879529-?	rs1879529	0	1879529	intron_variant	FALSE	0.7214	4e-9	8.397940008672037	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7214	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17p13.3	17	560603	VPS53	VPS53, VPS53	NA	NA	ENSG00000141252, ENSG00000283883	NA	NA	rs741677-?	rs741677	0	741677	intron_variant	FALSE	0.5798	4e-8	7.3979400086720375	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5798	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q11.2	17	30837005	ATAD5	ATAD5	NA	NA	ENSG00000176208	NA	NA	rs3764419-?	rs3764419	0	3764419	intron_variant	FALSE	0.6093	2e-6	5.698970004336019	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6093	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q23.2	17	61419916	C17orf82	LINC02875 - TBX4	ENSG00000187013	ENSG00000121075	NA	6636	32488	rs757608-?	rs757608	0	757608	regulatory_region_variant	TRUE	0.3207	2e-10	9.698970004336019	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3207	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	18q11.2	18	23147647	CABLES1	CABLES1	NA	NA	ENSG00000134508	NA	NA	rs4800452-?	rs4800452	0	4800452	intron_variant	FALSE	0.7873	1e-17	17	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7873	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	19p13.2	19	8577276	MYO1F	MYO1F	NA	NA	ENSG00000142347	NA	NA	rs4542783-?	rs4542783	0	4542783	non_coding_transcript_exon_variant	FALSE	0.5462	9e-8	7.045757490560675	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5462	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	19q13.11	19	33402102	PEPD	PEPD	NA	NA	ENSG00000124299	NA	NA	rs3786897-?	rs3786897	0	3786897	intron_variant	FALSE	0.41559999999999997	8e-8	7.096910013008056	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.41559999999999997	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	20p12.3	20	6642727	LOC149844, BMP2	NA - LINC01713	NA	ENSG00000228482	NA	NA	88353	rs979012-?	rs979012	0	979012	intergenic_variant	TRUE	0.3493	3e-9	8.522878745280337	(EA)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3493	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p36.13	1	16981663	MFAP2	MFAP2 - ATP13A2	ENSG00000117122	ENSG00000159363	NA	1031	4295	rs9435732-?	rs9435732	0	9435732	intron_variant	TRUE	0.7301	1e-11	11	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7301	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p13.2	1	112509564	WNT2B	WNT2B	NA	NA	ENSG00000134245	NA	NA	rs3790606-?	rs3790606	0	3790606	intron_variant	FALSE	0.6473	1e-7	7	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6473	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118310352	SPAG17	RNA5SP56 - NA	ENSG00000222209	NA	NA	45863	NA	rs12731372-?	rs12731372	0	12731372	regulatory_region_variant	TRUE	0.766	6e-11	10.221848749616356	(men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.766	NA	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	6p21.32	6	32690139	HLA-DQA2, HLA-DQB1	HLA-DQB1 - MTCO3P1	ENSG00000206237	ENSG00000237145	NA	21756	15985	rs7775055-G	rs7775055	0	7775055	TF_binding_site_variant	TRUE	0.02	3e-174	173.52287874528034	(dominant model)	6.01	[5.30-6.81]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.02	6.01	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	1p13.2	1	113761186	PTPN22	PHTF1 - RSBN1	ENSG00000116793	ENSG00000081019	NA	1697	646	rs6679677-A	rs6679677	0	6679677	intergenic_variant	TRUE	0.1	3e-25	24.522878745280337	(additive model)	1.59	[1.45-1.73]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.1	1.59	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	2q32.3	2	191108308	STAT4	STAT4	NA	NA	ENSG00000138378	NA	NA	rs10174238-G	rs10174238	0	10174238	intron_variant	FALSE	0.23	1e-13	13	(additive model)	1.29	[1.20-1.37]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.23	1.29	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	18p11.21	18	12782449	PTPN2	LINC01882 - PTPN2	ENSG00000260302	ENSG00000175354	NA	6309	3029	rs2847293-A	rs2847293	0	2847293	intergenic_variant	TRUE	0.17	1e-12	12	(additive model)	1.31	[1.22-1.41]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.17	1.31	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	5q11.2	5	56146422	ANKRD55	ANKRD55	NA	NA	ENSG00000164512	NA	NA	rs10213692-?	rs10213692	0	10213692	intron_variant	FALSE	0.75	3e-11	10.522878745280337	(additive model)	1.2658228	[1.25-1.35]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.75	1.2658228	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	4q27	4	122466445	IL2, IL21	IL2 - IL21	ENSG00000109471	ENSG00000138684	NA	9720	143663	rs1479924-?	rs1479924	0	1479924	intergenic_variant	TRUE	0.71	6e-11	10.221848749616356	(additive model)	1.2658228	[1.18-1.35]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.71	1.2658228	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	19p13.2	19	10352442	TYK2	TYK2	NA	NA	ENSG00000105397	NA	NA	rs34536443-?	rs34536443	0	34536443	missense_variant	FALSE	0.95	1e-10	10	(additive model)	1.7857143	[1.49-2.13]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.95	1.7857143	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	10p15.1	10	6047878	IL2RA	IL2RA	NA	NA	ENSG00000134460	NA	NA	rs7909519-?	rs7909519	0	7909519	intron_variant	FALSE	0.89	8e-10	9.096910013008056	(additive model)	1.3888888	[1.25-1.56]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.89	1.3888888	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	12q24.12	12	111494996	SH2B3, ATXN2	ATXN2	NA	NA	ENSG00000204842	NA	NA	rs7137828-C	rs7137828	0	7137828	intron_variant	FALSE	0.49	2e-9	8.698970004336019	(additive model)	1.2	[1.13-1.28]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.49	1.2	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	5q15	5	97021474	ERAP2, LNPEP	LNPEP	NA	NA	ENSG00000113441	NA	NA	rs27293-A	rs27293	0	27293	intron_variant	FALSE	0.44	7e-9	8.154901959985743	(dominant model)	1.31	[1.19-1.43]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.44	1.31	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	22q11.21	22	21568615	UBE2L3	UBE2L3	NA	NA	ENSG00000185651	NA	NA	rs2266959-A	rs2266959	0	2266959	intron_variant	FALSE	0.19	6e-9	8.221848749616356	(dominant model)	1.24	[1.15-1.33]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.19	1.24	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	5q31.1	5	132461855	IRF1, C5orf56	IRF1-AS1, IRF1	NA	NA	ENSG00000197536, ENSG00000125347	NA	NA	rs6894249-?	rs6894249	0	6894249	non_coding_transcript_exon_variant	FALSE	0.61	1e-9	9	(dominant model)	1.3157895	[1.20-1.43]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.61	1.3157895	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	21q22.12	21	35340290	RUNX1	RUNX1	NA	NA	ENSG00000159216	NA	NA	rs8129030-?	rs8129030	0	8129030	intron_variant	FALSE	0.63	5e-9	8.301029995663981	(dominant model)	1.2820514	[1.19-1.41]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.63	1.2820514	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	22q12.3	22	37137994	IL2RB	IL2RB	NA	NA	ENSG00000100385	NA	NA	rs2284033-?	rs2284033	0	2284033	intron_variant	FALSE	0.56	2e-8	7.698970004336019	(additive model)	1.1904762	[1.12-1.27]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.56	1.1904762	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	1q21.3	1	154406893	ATP8B2, IL6R	IL6R	NA	NA	ENSG00000160712	NA	NA	rs72698115-C	rs72698115	0	72698115	intron_variant	FALSE	0.1	1e-8	8	(dominant model)	1.36	[1.22-1.52]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.1	1.36	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	10q23.31	10	89002619	FAS	FAS	NA	NA	ENSG00000026103	NA	NA	rs7069750-C	rs7069750	0	7069750	non_coding_transcript_exon_variant	FALSE	0.44	3e-8	7.522878745280337	(additive model)	1.18	[1.11-1.25]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.44	1.18	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	14q24.1	14	68793871	ZFP36L1	ZFP36L1	NA	NA	ENSG00000185650	NA	NA	rs3825568-?	rs3825568	0	3825568	5_prime_UTR_variant	FALSE	0.56	1e-8	8	(dominant model)	1.2987013	[1.19-1.43]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.56	1.2987013	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	12p13.31	12	6384185	LTBR	LTBR	NA	NA	ENSG00000111321	NA	NA	rs10849448-A	rs10849448	0	10849448	5_prime_UTR_variant	FALSE	0.24	5e-9	8.301029995663981	(additive model)	1.24	[1.15-1.33]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.24	1.24	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	7p15.3	7	22769871	IL6	MTCYBP42 - TOMM7	ENSG00000228803	ENSG00000196683	NA	21067	42757	rs6946509-T	rs6946509	0	6946509	intergenic_variant	TRUE	0.45	3e-8	7.522878745280337	(additive model)	1.19	[1.12-1.26]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.45	1.19	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	13q14.11	13	39781776	COG6	COG6	NA	NA	ENSG00000133103	NA	NA	rs9532434-?	rs9532434	0	9532434	intron_variant	FALSE	0.64	5e-8	7.301029995663981	(additive model)	1.1904762	[1.12-1.27]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.64	1.1904762	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	13q14.11	13	42481900	Intergenic	LINC02341	NA	NA	ENSG00000283554	NA	NA	rs34132030-A	rs34132030	0	34132030	intron_variant	FALSE	0.32	2e-7	6.698970004336019	(additive model)	1.18	[1.11-1.26]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.32	1.18	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	3p21.31	3	46212159	CCR1, CCR3	CCR3	NA	NA	ENSG00000183625	NA	NA	rs79893749-?	rs79893749	0	79893749	intron_variant	FALSE	0.85	2e-7	6.698970004336019	(additive model)	1.2820514	[1.16-1.39]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.85	1.2820514	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	11p13	11	36322143	PRR5L	PRR5L	NA	NA	ENSG00000135362	NA	NA	rs7127214-?	rs7127214	0	7127214	intron_variant	FALSE	0.65	2e-8	7.698970004336019	(dominant model)	1.2820514	[1.18-1.41]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.65	1.2820514	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	16p13.13	16	11377557	PRM1, RMI2	RMI2	NA	NA	ENSG00000175643	NA	NA	rs11074967-?	rs11074967	0	11074967	intron_variant	FALSE	0.58	2e-7	6.698970004336019	(additive model)	1.1764705	[1.10-1.25]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.58	1.1764705	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	1p36.11	1	24870664	RUNX3	CLIC4 - RUNX3	ENSG00000169504	ENSG00000020633	NA	26343	28847	rs4648881-G	rs4648881	0	4648881	intergenic_variant	TRUE	0.49	5e-7	6.301029995663981	(additive model)	1.16	[1.10-1.23]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.49	1.16	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	3q29	3	196184705	intergenic	LINC00885 - ZDHHC19	ENSG00000224652	ENSG00000163958	NA	23812	12747	rs11428167-AT	rs11428167	0	11428167	intergenic_variant	TRUE	0.1354	4e-20	19.397940008672037	NA	0.04815017	[0.038-0.058] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1354	NA	0.04815017
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	4p15.32	4	15591241	CC2D2A	CC2D2A	NA	NA	ENSG00000048342	NA	NA	rs7684446-T	rs7684446	0	7684446	non_coding_transcript_exon_variant	FALSE	0.4273	3e-9	8.522878745280337	NA	0.02135863	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4273	NA	0.02135863
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	4q12	4	54540932	intergenic	NA - LINC02260	NA	ENSG00000250456	NA	NA	62279	rs170121-C	rs170121	0	170121	intergenic_variant	TRUE	0.2198	3e-127	126.52287874528034	NA	0.1031647	[0.095-0.112] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2198	NA	0.1031647
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	4q12	4	54542832	intergenic	LINC02283 - LINC02260	ENSG00000248184	ENSG00000250456	NA	186878	60379	rs218265-C	rs218265	0	218265	intergenic_variant	TRUE	0.1571	3e-148	147.52287874528034	NA	0.1283842	[0.12-0.14] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1571	NA	0.1283842
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	4q21.1	4	76489165	SHROOM3	SHROOM3	NA	NA	ENSG00000138771	NA	NA	rs4859682-A	rs4859682	0	4859682	intron_variant	FALSE	0.4549	1e-13	13	NA	0.02641173	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4549	NA	0.02641173
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	4q21.21	4	80259918	intergenic	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675	NA	55589	6721	rs10857147-T	rs10857147	0	10857147	intergenic_variant	TRUE	0.2905	1e-10	10	NA	0.02512283	[0.017-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2905	NA	0.02512283
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	4q21.22	4	82974079	LIN54	LIN54	NA	NA	ENSG00000189308	NA	NA	rs13103322-G	rs13103322	0	13103322	intron_variant	FALSE	0.1997	6e-12	11.221848749616356	NA	0.03149645	[0.023-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1997	NA	0.03149645
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	4q22.1	4	87123184	AFF1	AFF1	NA	NA	ENSG00000172493	NA	NA	rs13108043-A	rs13108043	0	13108043	intron_variant	FALSE	0.1876	1e-11	11	NA	0.03093505	[0.022-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1876	NA	0.03093505
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	5p15.33	5	1104823	SLC12A7	SLC12A7, SLC12A7	NA	NA	ENSG00000113504, ENSG00000276482	NA	NA	rs35188965-T	rs35188965	0	35188965	intron_variant	FALSE	0.5794	5e-13	12.301029995663981	NA	0.02596179	[0.019-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5794	NA	0.02596179
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	5p15.33	5	1284020	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs4449583-T	rs4449583	0	4449583	intron_variant	FALSE	0.3259	2e-25	24.69897000433602	NA	0.03983159	[0.032-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.3259	NA	0.03983159
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	5p13.2	5	34504277	intergenic	NA	NA	NA	NA	NA	NA	rs6880621-A	rs6880621	0	6880621	intergenic_variant	TRUE	0.5302	4e-9	8.397940008672037	NA	0.02133613	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5302	NA	0.02133613
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	5q13.3	5	77181995	intergenic	ZBED3-AS1 - PDE8B	ENSG00000250802	ENSG00000113231	NA	15086	28454	rs2928167-G	rs2928167	0	2928167	intron_variant	TRUE	0.1277	7e-10	9.154901959985743	NA	0.03286629	[0.022-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1277	NA	0.03286629
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	5q14.3	5	88895818	MEF2C-AS1, MEF2C	MEF2C-AS1, MEF2C	NA	NA	ENSG00000248309, ENSG00000081189	NA	NA	rs2067663-T	rs2067663	0	2067663	intron_variant	FALSE	0.2213	6e-14	13.221848749616356	NA	0.03227871	[0.024-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2213	NA	0.03227871
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	5q33.2	5	154655826	intergenic	MIR3141 - MIR1303	ENSG00000264760	ENSG00000221552	NA	59754	29950	rs5872391-G	rs5872391	0	5872391	intergenic_variant	TRUE	0.3276	1e-11	11	NA	0.02595659	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.3276	NA	0.02595659
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	5q35.3	5	177353246	LMAN2, RGS14	LMAN2 - RGS14	ENSG00000169223	ENSG00000169220	NA	1578	4678	rs35660843-C	rs35660843	0	35660843	regulatory_region_variant	TRUE	0.2949	9e-10	9.045757490560675	NA	0.02450671	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2949	NA	0.02450671
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p25.3	6	2050557	GMDS	GMDS	NA	NA	ENSG00000112699	NA	NA	rs115986297-G	rs115986297	0	115986297	intron_variant	FALSE	0.5428	6e-19	18.221848749616356	NA	0.03173454	[0.025-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5428	NA	0.03173454
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p24.3	6	7232156	RREB1	RREB1	NA	NA	ENSG00000124782	NA	NA	rs75757892-T	rs75757892	0	75757892	intron_variant	FALSE	0.1826	6e-12	11.221848749616356	NA	0.03181995	[0.023-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1826	NA	0.03181995
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p23	6	15176868	intergenic	RN7SL332P - JARID2-DT	ENSG00000242989	ENSG00000271888	NA	63647	67055	rs9464759-C	rs9464759	0	9464759	intergenic_variant	TRUE	0.0773	7e-13	12.154901959985743	NA	0.04792764	[0.035-0.061] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0773	NA	0.04792764
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p22.2	6	26092913	HFE	HFE	NA	NA	ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	FALSE	0.0841	5e-15	14.301029995663981	NA	0.04991289	[0.037-0.062] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0841	NA	0.04991289
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p22.2	6	26118310	HIST1H2BC	H2BC4	NA	NA	ENSG00000180596	NA	NA	rs2307823-C	rs2307823	0	2307823	intron_variant	FALSE	0.809	3e-13	12.522878745280337	NA	0.03590734	[0.026-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.809	NA	0.03590734
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	NA	NA	NA	HLA-A	NA	NA	NA	NA	NA	NA	chr6:29910771-T	chr6:29910771	0	NA	NA	TRUE	0.1581	2e-16	15.698970004336019	NA	0.04204999	[0.032-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1581	NA	0.04204999
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.33	6	31347631	intergenic	LINC02571 - HLA-B	ENSG00000256166	ENSG00000206450	NA	45989	6241	rs111721712-CT	rs111721712	1	11401849	intron_variant	TRUE	0.4708	1e-26	26	NA	0.03814722	[0.031-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4708	NA	0.03814722
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.32	6	32638979	HLA-DQA1	HLA-DQA1, HLA-DQA1	NA	NA	ENSG00000206305, ENSG00000196735	NA	NA	rs9272535-A	rs9272535	0	9272535	missense_variant	FALSE	0.2454	6e-30	29.221848749616356	NA	0.04727792	[0.039-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2454	NA	0.04727792
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.31	6	34210076	intergenic	KRT18P9 - CYCSP55	ENSG00000271231	ENSG00000214810	NA	18997	9363	rs185139895-A	rs185139895	0	185139895	intergenic_variant	TRUE	0.0442	7e-10	9.154901959985743	NA	0.05333902	[0.036-0.07] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0442	NA	0.05333902
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.2	6	36634250	intergenic	MIR3925 - RNU1-88P	ENSG00000263894	ENSG00000238554	NA	11738	5295	rs747844459-T	rs747844459	0	747844459	regulatory_region_variant	TRUE	0.0015	2e-10	9.698970004336019	NA	0.3144035	[0.22-0.41] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0015	NA	0.3144035
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.1	6	41884878	USP49	USP49	NA	NA	ENSG00000164663	NA	NA	rs1319012-A	rs1319012	0	1319012	intron_variant	FALSE	0.923	2e-10	9.698970004336019	NA	0.04451332	[0.031-0.058] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.923	NA	0.04451332
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.1	6	41953503	CCND3	CCND3	NA	NA	ENSG00000112576	NA	NA	rs10947997-T	rs10947997	0	10947997	intron_variant	FALSE	0.1771	1e-58	58	NA	0.07501178	[0.066-0.084] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.1771	NA	0.07501178
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.1	6	41957260	CCND3	CCND3	NA	NA	ENSG00000112576	NA	NA	rs112233623-T	rs112233623	0	112233623	intron_variant	FALSE	0.0105	7e-40	39.15490195998574	NA	0.2492646	[0.21-0.29] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0105	NA	0.2492646
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.1	6	41957421	CCND3	CCND3	NA	NA	ENSG00000112576	NA	NA	rs9349205-A	rs9349205	0	9349205	intron_variant	FALSE	0.2513	3e-85	84.52287874528034	NA	0.07981425	[0.072-0.088] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2513	NA	0.07981425
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.1	6	43774889	VEGFA	VEGFA	NA	NA	ENSG00000112715	NA	NA	rs833070-C	rs833070	0	833070	non_coding_transcript_exon_variant	FALSE	0.4996	3e-16	15.522878745280337	NA	0.0289477	[0.022-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4996	NA	0.0289477
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.1	6	43834169	intergenic	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	47682	10709	rs869197558-C	rs869197558	1	5875851	intron_variant	TRUE	0.8428	3e-13	12.522878745280337	NA	0.03591032	[0.026-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.8428	NA	0.03591032
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.1	6	43842065	intergenic	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	55578	2813	rs9472135-C	rs9472135	0	9472135	intron_variant	TRUE	0.3059	5e-23	22.30102999566398	NA	0.03799032	[0.03-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.3059	NA	0.03799032
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.1	6	43973400	intergenic	NA - SCIRT	NA	ENSG00000237686	NA	NA	22323	rs17287978-C	rs17287978	0	17287978	regulatory_region_variant	TRUE	0.0487	6e-16	15.221848749616356	NA	0.0670582	[0.051-0.083] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0487	NA	0.0670582
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6p21.1	6	44062274	RP5-1120P11.1	SCIRT	NA	NA	ENSG00000237686	NA	NA	rs833805-G	rs833805	0	833805	non_coding_transcript_exon_variant	FALSE	0.8865	3e-27	26.522878745280337	NA	0.0651929	[0.053-0.077] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.8865	NA	0.0651929
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6q21	6	109268801	C6orf183	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs9487023-G	rs9487023	0	9487023	intron_variant	FALSE	0.4456	5e-65	64.30102999566398	NA	0.06080067	[0.054-0.068] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4456	NA	0.06080067
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6q22.33	6	127127104	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs1936807-G	rs1936807	0	1936807	intron_variant	FALSE	0.5182	5e-11	10.301029995663981	NA	0.02339011	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5182	NA	0.02339011
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6q23.3	6	135047176	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs9399135-A	rs9399135	0	9399135	intron_variant	FALSE	0.4958	1e-22	22	NA	0.03472818	[0.028-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4958	NA	0.03472818
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6q23.3	6	135091498	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs41294858-C	rs41294858	0	41294858	intron_variant	FALSE	0.0992	6e-113	112.22184874961636	NA	0.1341788	[0.12-0.15] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0992	NA	0.1341788
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6q23.3	6	135097778	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs7776054-G	rs7776054	0	7776054	intron_variant	FALSE	0.2603	0	469	NA	0.1877004	[0.18-0.2] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.2603	NA	0.1877004
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6q24.1	6	139519556	intergenic	LINC01625 - ATP5PBP6	ENSG00000238099	ENSG00000219806	NA	44898	94882	rs592423-C	rs592423	0	592423	intron_variant	TRUE	0.5539	3e-39	38.52287874528034	NA	0.04677355	[0.04-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.5539	NA	0.04677355
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	NA	NA	NA	intergenic	NA	NA	NA	NA	NA	NA	chr6:139843192-T	chr6:139843192	0	NA	NA	TRUE	0.9628	7e-26	25.154901959985743	NA	0.1010159	[0.082-0.12] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.9628	NA	0.1010159
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	6q26	6	164057356	intergenic	RN7SL366P - C6orf118	ENSG00000266128	ENSG00000112539	NA	216504	1222308	rs381500-A	rs381500	0	381500	intergenic_variant	TRUE	0.452	1e-14	14	NA	0.02755191	[0.021-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.452	NA	0.02755191
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	7p22.3	7	617300	PRKAR1B	PRKAR1B	NA	NA	ENSG00000188191	NA	NA	rs71016890-C	rs71016890	0	71016890	intron_variant	FALSE	0.6445	4e-12	11.397940008672037	NA	0.02581188	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6445	NA	0.02581188
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	7p22.3	7	1246931	intergenic	UNCX - MICALL2	ENSG00000164853	ENSG00000164877	NA	9605	181534	rs62435145-T	rs62435145	0	62435145	regulatory_region_variant	TRUE	0.6916	6e-16	15.221848749616356	NA	0.03159166	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6916	NA	0.03159166
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	7p13	7	44768624	ZMIZ2	ZMIZ2	NA	NA	ENSG00000122515	NA	NA	rs1050338-A	rs1050338	0	1050338	3_prime_UTR_variant	FALSE	0.456	1e-17	17	NA	0.03055909	[0.024-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.456	NA	0.03055909
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	7p12.2	7	50360284	IKZF1	IKZF1	NA	NA	ENSG00000185811	NA	NA	rs6592965-A	rs6592965	0	6592965	intron_variant	FALSE	0.4547	1e-43	43	NA	0.04951579	[0.043-0.057] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.4547	NA	0.04951579
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	7q21.11	7	80667650	CD36	CD36	NA	NA	ENSG00000135218	NA	NA	rs144658219-GTACTTGAT	rs144658219	1	57149211	intron_variant	FALSE	0.42	2e-12	11.698970004336019	NA	0.02568203	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.42	NA	0.02568203
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	7q22.1	7	99968131	AZGP1	AZGP1	NA	NA	ENSG00000160862	NA	NA	rs187130073-G	rs187130073	0	187130073	missense_variant	FALSE	0.0066	5e-12	11.301029995663981	NA	0.1546703	[0.11-0.2] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0066	NA	0.1546703
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	7q22.1	7	100638347	TFR2	TFR2	NA	NA	ENSG00000106327	NA	NA	rs7385804-A	rs7385804	0	7385804	intron_variant	FALSE	0.6251	4e-90	89.39794000867204	NA	0.07396288	[0.067-0.081] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.6251	NA	0.07396288
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Red blood cell count	172,952 European ancestry individuals	NA	7q22.1	7	100711557	POP7	POP7 - EPO	ENSG00000172336	ENSG00000130427	NA	4071	8911	rs143593369-G	rs143593369	0	143593369	intergenic_variant	TRUE	0.0092	3e-38	37.52287874528034	NA	0.287167	[0.24-0.33] unit decrease	Affymetrix [~ 2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004601	Genome-wide genotyping array	0.0092	NA	0.287167
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	3q13.33	3	119502217	TIMMDC1, CD80	TIMMDC1	NA	NA	ENSG00000113845	NA	NA	rs11714843-A	rs11714843	0	11714843	intron_variant	FALSE	0.18	4e-7	6.3979400086720375	(additive model)	1.22	[1.13-1.31]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.18	1.22	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	7p15.1	7	28147725	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs73300638-C	rs73300638	0	73300638	intron_variant	FALSE	0.11	1e-7	7	(additive model)	1.28	[1.17-1.41]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.11	1.28	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	2q11.2	2	100217755	AFF3, LONRF2	LINC01104	NA	NA	ENSG00000232084	NA	NA	rs10194635-T	rs10194635	0	10194635	intron_variant	FALSE	0.39	8e-7	6.096910013008056	(dominant model)	1.24	[1.14-1.36]	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	0.39	1.24	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	2q32.2	2	191009521	STAT4	STAT1	NA	NA	ENSG00000115415	NA	NA	rs45539732-?	rs45539732	0	45539732	intron_variant	FALSE	NR	7e-8	7.154901959985743	(conditioned on rs10174238)	1.53	NA	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	NA	1.53	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	18p11.21	18	12885121	PTPN2	PTPN2	NA	NA	ENSG00000175354	NA	NA	rs149850873-?	rs149850873	0	149850873	intron_variant	FALSE	NR	5e-7	6.301029995663981	(conditioned on rs2847293)	1.56	NA	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	NA	1.56	NA
2018-04-25	23603761	Hinks A	2013-04-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	2,816 European ancestry cases, 13,056 European ancestry controls	NA	10p15.1	10	6053447	IL2RA	IL2RA	NA	NA	ENSG00000134460	NA	NA	rs2476491-?	rs2476491	0	2476491	intron_variant	FALSE	NR	1e-6	6	(conditioned on rs7909519)	1.1904762	NA	Illumina [123003]	N	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019	GCST005528	Targeted genotyping array [ImmunoChip]	NA	1.1904762	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4q35.2	4	186286227	F11, F11-AS1	F11, F11-AS1	NA	NA	ENSG00000088926, ENSG00000251165	NA	NA	rs2289252-T	rs2289252	0	2289252	non_coding_transcript_exon_variant	FALSE	0.4127144	5e-25	24.30102999566398	(Coagulation Factor XI)	0.4419	[0.36-0.52] unit increase	Affymetrix [509946]	N	factor XI measurement	http://www.ebi.ac.uk/efo/EFO_0004694	GCST004365	Genome-wide genotyping array	0.4127144	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3p26.2	3	3098273	IL5RA, SNORA43	IL5RA	NA	NA	ENSG00000091181	NA	NA	rs2290610-C	rs2290610	0	2290610	missense_variant	FALSE	0.3636821	8e-28	27.096910013008056	(Interleukin-5 receptor subunit alpha)	0.4887	[0.4-0.57] unit increase	Affymetrix [509946]	N	interleukin 5 receptor subunit alpha measurement	http://www.ebi.ac.uk/efo/EFO_0008186	GCST004365	Genome-wide genotyping array	0.3636821	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6q25.3	6	160085430	IGF2R, RP11-288H12.3	IGF2R	NA	NA	ENSG00000197081	NA	NA	rs2297363-A	rs2297363	0	2297363	intron_variant	FALSE	0.1182093	8e-31	30.096910013008056	(Cation-independent mannose-6-phosphate receptor)	0.7573	[0.63-0.88] unit increase	Affymetrix [509946]	N	cation-independent mannose-6-phosphate receptor measurement	http://www.ebi.ac.uk/efo/EFO_0008075	GCST004365	Genome-wide genotyping array	0.1182093	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q27.3	3	186727263	KNG1, RP11-573D15.8, RP11-795A2.3	KNG1	NA	NA	ENSG00000113889	NA	NA	rs2304456-G	rs2304456	0	2304456	missense_variant	FALSE	0.1029116	3e-97	96.52287874528034	(Kininogen-1)	1.366	[1.25-1.48] unit decrease	Affymetrix [509946]	N	kininogen-1 measurement	http://www.ebi.ac.uk/efo/EFO_0008198	GCST004365	Genome-wide genotyping array	0.1029116	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q27.3	3	186727263	KNG1, RP11-573D15.8, RP11-795A2.3	KNG1	NA	NA	ENSG00000113889	NA	NA	rs2304456-G	rs2304456	0	2304456	missense_variant	FALSE	0.1029116	1e-10	10	(Leucine carboxyl methyltransferase 1)	0.4564	[0.32-0.59] unit increase	Affymetrix [509946]	N	leucine carboxyl methyltransferase 1 measurement	http://www.ebi.ac.uk/efo/EFO_0008207	GCST004365	Genome-wide genotyping array	0.1029116	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	12q22	12	94236253	PLXNC1	PLXNC1	NA	NA	ENSG00000136040	NA	NA	rs2361355-G	rs2361355	0	2361355	intron_variant	FALSE	0.4064386	9e-27	26.045757490560675	(Plexin-C1)	0.4635	[0.38-0.55] unit decrease	Affymetrix [509946]	N	plexin-C1 measurement	http://www.ebi.ac.uk/efo/EFO_0008266	GCST004365	Genome-wide genotyping array	0.4064386	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	22q12.3	22	32846175	SYN3, RP1-309I22.2, TIMP3	SYN3, TIMP3	NA	NA	ENSG00000185666, ENSG00000100234	NA	NA	rs241890-T	rs241890	0	241890	intron_variant	FALSE	0.193662	3e-20	19.522878745280337	(Metalloproteinase inhibitor 3)	0.4995	[0.4-0.6] unit decrease	Affymetrix [509946]	N	metalloproteinase inhibitor 3 measurement	http://www.ebi.ac.uk/efo/EFO_0008231	GCST004365	Genome-wide genotyping array	0.193662	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	20q11.22	20	35762744	CPNE1, FER1L4, RBM39, SCAND1, PHF20, SPAG4, RBM12, NFS1, ROMO1, RP1-309K20.6, RN7SKP271, RNU6-759P, RPF2P1, COX7BP2, Y_RNA, HIGD1AP16, RNU4-40P, RNU6-937P, CNBD2	RPF2P1 - U6	ENSG00000225357	ENSG00000266435	NA	9025	7041	rs2425143-T	rs2425143	0	2425143	regulatory_region_variant	TRUE	0.1048144	4e-73	72.39794000867204	(Copine-1)	1.206	[1.09-1.33] unit decrease	Affymetrix [509946]	N	copine-1 measurement	http://www.ebi.ac.uk/efo/EFO_0008102	GCST004365	Genome-wide genotyping array	0.1048144	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q27.3	3	186620038	RP11-573D15.8, AHSG	AHSG	NA	NA	ENSG00000145192	NA	NA	rs2518136-T	rs2518136	0	2518136	intron_variant	FALSE	0.4582495	2e-39	38.69897000433602	(Alpha-2-HS-glycoprotein)	0.5564	[0.48-0.64] unit decrease	Affymetrix [509946]	N	alpha-2-HS-glycoprotein measurement	http://www.ebi.ac.uk/efo/EFO_0008020	GCST004365	Genome-wide genotyping array	0.4582495	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	5q15	5	96802179	ERAP1, CTD-2260A17.1, CTD-2260A17.3, AC008906.1, CTD-2260A17.2	ERAP1	NA	NA	ENSG00000164307	NA	NA	rs26496-A	rs26496	0	26496	intron_variant	FALSE	0.2039275	6e-123	122.22184874961636	(Endoplasmic reticulum aminopeptidase 1)	1.13	[1.05-1.21] unit increase	Affymetrix [509946]	N	endoplasmic reticulum aminopeptidase 1 measurement	http://www.ebi.ac.uk/efo/EFO_0008119	GCST004365	Genome-wide genotyping array	0.2039275	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19q13.41	19	51092879	CTU1	KLK14 - CTU1	ENSG00000129437	ENSG00000142544	NA	8634	4727	rs2691273-G	rs2691273	0	2691273	intergenic_variant	TRUE	0.4632427	3e-73	72.52287874528034	(Sialic acid-binding Ig-like lectin 9)	0.7635	[0.69-0.84] unit increase	Affymetrix [509946]	N	sialic acid-binding Ig-like lectin 9 measurement	http://www.ebi.ac.uk/efo/EFO_0008286	GCST004365	Genome-wide genotyping array	0.4632427	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	21q21.3	21	26932893	ADAMTS5, AP001601.2, MIR4759	ADAMTS5	NA	NA	ENSG00000154736	NA	NA	rs2830585-T	rs2830585	0	2830585	missense_variant	FALSE	0.1581325	4e-104	103.39794000867204	(A disintegrin and metalloproteinase with thrombospondin motifs 5)	1.073	[0.99-1.16] unit decrease	Affymetrix [509946]	N	a disintegrin and metalloproteinase with thrombospondin motifs 5 measurement	http://www.ebi.ac.uk/efo/EFO_0008326	GCST004365	Genome-wide genotyping array	0.1581325	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	10q11.23	10	50258722	DYNC1I2P1	ASAH2	NA	NA	ENSG00000188611	NA	NA	rs2842126-A	rs2842126	0	2842126	intron_variant	FALSE	0.2299197	6e-34	33.221848749616356	(Neutral ceramidase)	0.6013	[0.51-0.69] unit decrease	Affymetrix [509946]	N	neutral ceramidase measurement	http://www.ebi.ac.uk/efo/EFO_0008247	GCST004365	Genome-wide genotyping array	0.2299197	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6p21.33	6	31422007	MICA, HCP5	MICA - LINC01149	ENSG00000235233	ENSG00000230174	NA	6692	19660	rs2844511-A	rs2844511	0	2844511	intron_variant	TRUE	0.3969849	4e-119	118.39794000867204	(MHC class I polypeptide-related sequence A)	0.9218	[0.85-0.99] unit increase	Affymetrix [509946]	N	MHC class I polypeptide-related sequence A measurement	http://www.ebi.ac.uk/efo/EFO_0008233	GCST004365	Genome-wide genotyping array	0.3969849	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	2q32.1	2	182838608	FRZB	FRZB	NA	NA	ENSG00000162998	NA	NA	rs288326-A	rs288326	0	288326	missense_variant	FALSE	0.1311558	9e-28	27.045757490560675	(Secreted frizzled-related protein 3)	0.6982	[0.58-0.82] unit increase	Affymetrix [509946]	N	Secreted frizzled-related protein 3 measurement	http://www.ebi.ac.uk/efo/EFO_0008277	GCST004365	Genome-wide genotyping array	0.1311558	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	2q23.3	2	151280667	RBM43, NMI	NMI	NA	NA	ENSG00000123609	NA	NA	rs289828-C	rs289828	0	289828	intron_variant	FALSE	0.4280684	2e-21	20.69897000433602	(Tumor necrosis factor-inducible gene 6 protein)	0.3948	[0.32-0.47] unit increase	Affymetrix [509946]	N	tumor necrosis factor-inducible gene 6 protein measurement	http://www.ebi.ac.uk/efo/EFO_0008311	GCST004365	Genome-wide genotyping array	0.4280684	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4q28.1	4	122836593	FGF2, AC021205.1, RP11-170N16.2	FGF2	NA	NA	ENSG00000138685	NA	NA	rs308403-T	rs308403	0	308403	intron_variant	FALSE	0.3192771	6e-39	38.221848749616356	(Fibroblast growth factor 2)	0.5896	[0.5-0.67] unit decrease	Affymetrix [509946]	N	fibroblast growth factor 2 measurement	http://www.ebi.ac.uk/efo/EFO_0008129	GCST004365	Genome-wide genotyping array	0.3192771	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6p21.33	6	31497270	HLA-B, MICB, DDX39B, HCG22, HLA-C, XXbac-BPG248L24.12, ZDHHC20P2, MICA, HCP5, SNORD84, LTB, LTA, LST1, NCR3, HCG27, XXbac-BPG299F13.14, XXbac-BPG299F13.15, XXbac-BPG299F13.16, MIR6891, DHFRP2, RNU6-283P, AL671883.1, FGFR3P1, HLA-S, XXbac-BPG181B23.7, LINC01149, XXbac-BPG181B23.6, Y_RNA, XXbac-BPG16N22.5, PPIAP9, DDX39B-AS1, SNORD117, ATP6V1G2-DDX39B, AL662801.1, ATP6V1G2, NFKBIL1, TNF	MICB, MICB, MICB, MICB, MICB, MICB, MICB	NA	NA	ENSG00000204516, ENSG00000224378, ENSG00000206449, ENSG00000234218, ENSG00000227772, ENSG00000238289, ENSG00000231372	NA	NA	rs3094005-T	rs3094005	0	3094005	intron_variant	FALSE	0.09437751	4e-38	37.39794000867204	(MHC class I polypeptide-related sequence B)	0.9308	[0.8-1.07] unit decrease	Affymetrix [509946]	N	MHC class I polypeptide-related sequence B measurement	http://www.ebi.ac.uk/efo/EFO_0008234	GCST004365	Genome-wide genotyping array	0.09437751	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4q13.3	4	73866095	CXCL1	PF4V1 - CXCL1	ENSG00000109272	ENSG00000163739	NA	11612	3298	rs3117600-G	rs3117600	0	3117600	intergenic_variant	TRUE	0.2966867	3e-120	119.52287874528034	(Growth-regulated alpha protein)	1.013	[0.94-1.09] unit increase	Affymetrix [509946]	N	growth-regulated alpha protein measurement	http://www.ebi.ac.uk/efo/EFO_0008146	GCST004365	Genome-wide genotyping array	0.2966867	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q12	17	34320525	CCL8, RP11-521P1.1	CCL8	NA	NA	ENSG00000108700	NA	NA	rs3138036-G	rs3138036	0	3138036	intron_variant	FALSE	0.1454363	2e-69	68.69897000433602	(C-C motif chemokine 7)	0.9997	[0.9-1.1] unit decrease	Affymetrix [509946]	N	C-C motif chemokine 7 measurement	http://www.ebi.ac.uk/efo/EFO_0008054	GCST004365	Genome-wide genotyping array	0.1454363	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q12	17	35976735	CCL16, CTB-186H2.3, CCL14, CCL15-CCL14	CCL16, CCL16	NA	NA	ENSG00000275095, ENSG00000275152	NA	NA	rs33995560-C	rs33995560	0	33995560	3_prime_UTR_variant	FALSE	0.08174524	2e-95	94.69897000433602	(C-C motif chemokine 16)	1.393	[1.28-1.51] unit decrease	Affymetrix [509946]	N	C-C motif chemokine 16 measurement	http://www.ebi.ac.uk/efo/EFO_0008044	GCST004365	Genome-wide genotyping array	0.08174524	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	13q31.3	13	91764804	GPC5	GPC5	NA	NA	ENSG00000179399	NA	NA	rs342706-C	rs342706	0	342706	intron_variant	FALSE	0.274323	1e-83	83	(Glypican-5)	0.8611	[0.78-0.94] unit decrease	Affymetrix [509946]	N	glypican-5 measurement	http://www.ebi.ac.uk/efo/EFO_0008139	GCST004365	Genome-wide genotyping array	0.274323	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	9p21.2	9	27197488	TEK, RNA5SP280, RP11-179D22.1	TEK	NA	NA	ENSG00000120156	NA	NA	rs35030851-T	rs35030851	0	35030851	missense_variant	FALSE	0.05070281	4e-21	20.397940008672037	(Angiopoietin-1 receptor, soluble)	0.9243	[0.74-1.11] unit increase	Affymetrix [509946]	N	angiopoietin-1 receptor, soluble measurement	http://www.ebi.ac.uk/efo/EFO_0008023	GCST004365	Genome-wide genotyping array	0.05070281	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	15q22.2	15	60484792	ICE2, RP11-745A24.1, ANXA2, RP11-745A24.2, RP11-745A24.3, RORA, RORA-AS1	RORA-AS1	NA	NA	ENSG00000245534	NA	NA	rs36032232-G	rs36032232	0	36032232	intron_variant	FALSE	0.1501004	7e-66	65.15490195998575	(Annexin A2)	0.97	[0.87-1.07] unit increase	Affymetrix [509946]	N	annexin A2 measurement	http://www.ebi.ac.uk/efo/EFO_0008027	GCST004365	Genome-wide genotyping array	0.1501004	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	11q24.2	11	126019631	CDON	CDON	NA	NA	ENSG00000064309	NA	NA	rs3740909-T	rs3740909	0	3740909	missense_variant	FALSE	0.07301108	4e-25	24.397940008672037	(Cell adhesion molecule-related/down-regulated by oncogenes)	0.8286	[0.68-0.98] unit decrease	Affymetrix [509946]	N	cell adhesion molecule-related/down-regulated by oncogenes measurement	http://www.ebi.ac.uk/efo/EFO_0008079	GCST004365	Genome-wide genotyping array	0.07301108	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q14.2	13	50207120	NR	DLEU1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2765762-C; rs2580195-T; rs2740520-C; rs2066632-A; rs2118963-A; rs2580187-A; rs17074018-A; rs2066629-A; rs2066647-T; rs7995192-C	rs2765762; rs2580195; rs2740520; rs2066632; rs2118963; rs2580187; rs17074018; rs2066629; rs2066647; rs7995192	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.14	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.14	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q14.3	13	54481796	NR	RPL13AP25 - N/A; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs16841-A; rs4885106-A; rs531161-C; rs9569048-A	rs16841; rs4885106; rs531161; rs9569048	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.014	8e-15	14.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.014	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q14.3	13	54481796	NR	RPL13AP25 - N/A; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs16841-A; rs4885106-G; rs531161-C; rs9569048-A	rs16841; rs4885106; rs531161; rs9569048	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.238	7e-10	9.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.238	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q21.2	13	60101124	NR	DIAPH3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12427712-A; rs2670491-C; rs11843015-T; rs386809-G; rs9317099-C; rs9646034-C; rs2137664-C; rs9538557-A; rs9528060-C; rs17669965-C; rs423521-A; rs7323094-A; rs1225840-C; rs11840069-A; rs2670473-G; rs2670474-C; rs9317098-C; rs17669147-G; rs2292525-G; rs9570258-T; rs411508-T; rs2762132-T; rs17057556-C; rs9538552-A	rs12427712; rs2670491; rs11843015; rs386809; rs9317099; rs9646034; rs2137664; rs9538557; rs9528060; rs17669965; rs423521; rs7323094; rs1225840; rs11840069; rs2670473; rs2670474; rs9317098; rs17669147; rs2292525; rs9570258; rs411508; rs2762132; rs17057556; rs9538552	0	NA	intron_variant; intron_variant; 5_prime_UTR_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	2e-21	20.69897000433602	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q21.2	13	60101124	NR	DIAPH3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12427712-A; rs2670491-C; rs11843015-T; rs386809-G; rs9317099-C; rs9646034-C; rs2137664-C; rs9538557-A; rs9528060-C; rs17669965-C; rs423521-A; rs7323094-A; rs1225840-C; rs11840069-A; rs2670473-G; rs2670474-C; rs9317098-A; rs17669147-G; rs2292525-G; rs9570258-T; rs411508-T; rs2762132-T; rs17057556-C; rs9538552-A	rs12427712; rs2670491; rs11843015; rs386809; rs9317099; rs9646034; rs2137664; rs9538557; rs9528060; rs17669965; rs423521; rs7323094; rs1225840; rs11840069; rs2670473; rs2670474; rs9317098; rs17669147; rs2292525; rs9570258; rs411508; rs2762132; rs17057556; rs9538552	0	NA	intron_variant; intron_variant; 5_prime_UTR_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.294	8e-14	13.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.294	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q21.31	13	62979513	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7999193-G; rs2203211-C; rs2805932-A; rs2805962-G; rs976195-G	rs7999193; rs2203211; rs2805932; rs2805962; rs976195	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.195	2e-10	9.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.195	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q21.33	13	68553746	NR	N/A - RPS3AP52; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs9529367-G; rs17557736-A; rs12184778-G; rs9541434-A; rs9317705-C; rs12859487-C; rs1391997-T	rs9529367; rs17557736; rs12184778; rs9541434; rs9317705; rs12859487; rs1391997	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	3e-7	6.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q21.33	13	72154243	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7987755-C; rs7985915-T; rs7996910-A; rs9542861-A; rs17195448-C; rs2038945-T; rs1326686-C; rs9318057-C	rs7987755; rs7985915; rs7996910; rs9542861; rs17195448; rs2038945; rs1326686; rs9318057	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	5e-17	16.30102999566398	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q21.33	13	72154243	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7987755-T; rs7985915-T; rs7996910-A; rs9542861-A; rs17195448-C; rs2038945-T; rs1326686-C; rs9318057-C	rs7987755; rs7985915; rs7996910; rs9542861; rs17195448; rs2038945; rs1326686; rs9318057	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.191	9e-8	7.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.191	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q21.33	13	72640091	NR	N/A - RPL21P110; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1440869-C; rs9543031-T; rs972434-T; rs17089636-T; rs9592852-T; rs9543032-G; rs1886199-C	rs1440869; rs9543031; rs972434; rs17089636; rs9592852; rs9543032; rs1886199	0	NA	intergenic_variant; regulatory_region_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	3e-18	17.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q21.33	13	72640091	NR	N/A - RPL21P110; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1440869-C; rs9543031-T; rs972434-T; rs17089636-T; rs9592852-G; rs9543032-G; rs1886199-C	rs1440869; rs9543031; rs972434; rs17089636; rs9592852; rs9543032; rs1886199	0	NA	intergenic_variant; regulatory_region_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.154	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.154	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q22.1	13	73279164	NR	RNY1P8 - N/A; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7987880-G; rs9543309-T; rs9573159-A; rs4883930-C; rs9543311-C; rs1410102-G; rs7998315-G; rs9592901-T; rs1928634-G; rs9573155-G; rs8002624-C	rs7987880; rs9543309; rs9573159; rs4883930; rs9543311; rs1410102; rs7998315; rs9592901; rs1928634; rs9573155; rs8002624	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.001	5e-17	16.30102999566398	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.001	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q22.1	13	73279164	NR	RNY1P8 - N/A; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7987880-G; rs9543309-T; rs9573159-A; rs4883930-C; rs9543311-C; rs1410102-G; rs7998315-G; rs9592901-T; rs1928634-T; rs9573155-G; rs8002624-C	rs7987880; rs9543309; rs9573159; rs4883930; rs9543311; rs1410102; rs7998315; rs9592901; rs1928634; rs9573155; rs8002624	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.154	6e-7	6.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.154	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q31.1	13	80182732	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs637153-A; rs8001401-A; rs7321259-T; rs2329154-C; rs9574580-C; rs11149155-G; rs7986411-T; rs1215445-C; rs1215447-G; rs482161-T	rs637153; rs8001401; rs7321259; rs2329154; rs9574580; rs11149155; rs7986411; rs1215445; rs1215447; rs482161	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; regulatory_region_variant; regulatory_region_variant	NA	0.005	1e-6	6	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.005	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q31.1	13	80182732	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs637153-A; rs8001401-A; rs7321259-T; rs2329154-C; rs9574580-C; rs11149155-G; rs7986411-T; rs1215445-C; rs1215447-A; rs482161-T	rs637153; rs8001401; rs7321259; rs2329154; rs9574580; rs11149155; rs7986411; rs1215445; rs1215447; rs482161	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; regulatory_region_variant; regulatory_region_variant	NA	0.105	3e-6	5.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.105	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q31.1	13	81653513	NR	N/A - PTMAP5; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs9531232-C; rs1602205-A; rs10507923-T; rs2329201-T; rs4432145-C	rs9531232; rs1602205; rs10507923; rs2329201; rs4432145	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.117	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.117	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q31.3	13	90542536	NR	LINC01049 - N/A; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7490259-C; rs7336431-C; rs1929045-A; rs1888299-G; rs1929036-T; rs7996193-A	rs7490259; rs7336431; rs1929045; rs1888299; rs1929036; rs7996193	0	NA	intergenic_variant; intron_variant; intergenic_variant; intron_variant; intergenic_variant; intron_variant	NA	0.0	7e-8	7.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q31.3	13	90542536	NR	LINC01049 - N/A; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7490259-C; rs7336431-C; rs1929045-G; rs1888299-G; rs1929036-T; rs7996193-A	rs7490259; rs7336431; rs1929045; rs1888299; rs1929036; rs7996193	0	NA	intergenic_variant; intron_variant; intergenic_variant; intron_variant; intergenic_variant; intron_variant	NA	0.154	1e-7	7	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.154	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q33.1	13	101616289	NR	ITGBL1; No mapped genes	NA	NA	NA	NA	NA	rs4772403-T; rs1898203-C	rs4772403; rs1898203	0	NA	intron_variant; intron_variant	NA	0.021	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.021	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q33.1	13	103254410	NR	No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2699342-G; rs2699325-T; rs2390886-G; rs2806337-T	rs2699342; rs2699325; rs2390886; rs2806337	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.017	7e-15	14.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.017	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q33.1	13	103254410	NR	No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2699342-G; rs2699325-T; rs2390886-A; rs2806337-T	rs2699342; rs2699325; rs2390886; rs2806337	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.268	2e-12	11.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.268	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q33.2	13	104812639	NR	N/A - RPL7P45; No mapped genes	NA	NA	NA	NA	NA	rs2782988-C; rs7982390-A	rs2782988; rs7982390	0	NA	intergenic_variant; intergenic_variant	NA	0.242	3e-12	11.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.242	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q33.2	13	104812639	NR	N/A - RPL7P45; No mapped genes	NA	NA	NA	NA	NA	rs2782988-T; rs7982390-A	rs2782988; rs7982390	0	NA	intergenic_variant; intergenic_variant	NA	0.232	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.232	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q33.2	13	105830179	NR	LINC00343 - N/A; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7322085-T; rs7320405-A; rs9514439-G	rs7322085; rs7320405; rs9514439	0	NA	intergenic_variant; intergenic_variant; intergenic_variant	NA	0.16	8e-8	7.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.16	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q34	13;13	110407858;110409668	NR	COL4A2; No mapped genes; COL4A2; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs9521747-C; rs7328731-A; rs4773180-G; rs4773179-A; rs4773178-A; rs9559792-C	rs9521747; rs7328731; rs4773180; rs4773179; rs4773178; rs9559792	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.228	1e-11	11	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.228	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q13.3	5	76424719	IQGAP2	IQGAP2	NA	NA	ENSG00000145703	NA	NA	rs10072221-C	rs10072221	0	10072221	intron_variant	FALSE	0.4911	1e-16	16	NA	0.02992938	[0.023-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4911	NA	0.02992938
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q13.3	5	76611026	IQGAP2	IQGAP2	NA	NA	ENSG00000145703	NA	NA	rs7722711-C	rs7722711	0	7722711	missense_variant	FALSE	0.0642	2e-18	17.69897000433602	NA	0.06466721	[0.05-0.079] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0642	NA	0.06466721
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q13.3	5	76665143	IQGAP2	IQGAP2	NA	NA	ENSG00000145703	NA	NA	rs34968964-C	rs34968964	0	34968964	missense_variant	FALSE	0.0051	1e-34	34	NA	0.3249945	[0.27-0.38] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0051	NA	0.3249945
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q13.3	5	76668682	IQGAP2	IQGAP2	NA	NA	ENSG00000145703	NA	NA	rs34950321-T	rs34950321	0	34950321	missense_variant	FALSE	0.0179	5e-54	53.30102999566398	NA	0.2105824	[0.18-0.24] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0179	NA	0.2105824
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	NA	NA	NA	IQGAP2	NA	NA	NA	NA	NA	NA	chr5:75996909-A	chr5:75996909	0	NA	NA	TRUE	0.0437	1e-204	204	NA	0.2696779	[0.25-0.29] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0437	NA	0.2696779
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	NA	NA	NA	TBCA	NA	NA	NA	NA	NA	NA	chr5:77071703-T	chr5:77071703	0	NA	NA	TRUE	0.3065	2e-10	9.698970004336019	NA	0.02513696	[0.017-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3065	NA	0.02513696
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q14.3	5	88884379	MEF2C, MEF2C-AS1	MEF2C-AS1, MEF2C	NA	NA	ENSG00000248309, ENSG00000081189	NA	NA	rs114694170-C	rs114694170	0	114694170	non_coding_transcript_exon_variant	FALSE	0.0592	9e-75	74.04575749056067	NA	0.1424178	[0.13-0.16] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0592	NA	0.1424178
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q23.2	5	123038764	RP11-359P5.1	PPIC-AS1	NA	NA	ENSG00000249996	NA	NA	rs7712401-T	rs7712401	0	7712401	intron_variant	FALSE	0.538	5e-10	9.301029995663981	NA	0.02264376	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.538	NA	0.02264376
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q31.1	5	132316836	AC034220.3, SLC22A4	MIR3936HG, SLC22A4	NA	NA	ENSG00000233006, ENSG00000197208	NA	NA	rs11950562-C	rs11950562	0	11950562	intron_variant	FALSE	0.4766	3e-33	32.52287874528034	NA	0.04343237	[0.036-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4766	NA	0.04343237
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q31.1	5	134500603	RNU6-456P	RNU6-456P - LINC01843	ENSG00000207222	ENSG00000251169	NA	319	5949	rs10900828-G	rs10900828	0	10900828	intergenic_variant	TRUE	0.5794	2e-9	8.698970004336019	NA	0.02231888	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5794	NA	0.02231888
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q31.3	5	141322493	AC005618.6, TAF7, AC005618.1	TAF7 - PCDHGA1	ENSG00000178913	ENSG00000204956	NA	1709	8021	rs563151485-T	rs563151485	0	563151485	intron_variant	TRUE	0.0075	2e-10	9.698970004336019	NA	0.1492659	[0.1-0.2] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0075	NA	0.1492659
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q31.3	5	141604894	DIAPH1	DIAPH1	NA	NA	ENSG00000131504	NA	NA	rs72792324-A	rs72792324	0	72792324	intron_variant	FALSE	0.032	4e-10	9.397940008672037	NA	0.06435557	[0.044-0.085] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.032	NA	0.06435557
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q33.3	5	159195524	RNF145	RNF145	NA	NA	ENSG00000145860	NA	NA	rs55801554-A	rs55801554	0	55801554	intron_variant	FALSE	0.2451	6e-58	57.221848749616356	NA	0.06764201	[0.059-0.076] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2451	NA	0.06764201
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q33.3	5	160173207	intergenic	PWWP2A - FABP6	ENSG00000170234	ENSG00000170231	NA	53757	14160	rs2546976-C	rs2546976	0	2546976	intergenic_variant	TRUE	0.6753	8e-33	32.096910013008056	NA	0.04625529	[0.039-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.6753	NA	0.04625529
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p25.2	6	3448411	SLC22A23	SLC22A23	NA	NA	ENSG00000137266	NA	NA	rs9378796-T	rs9378796	0	9378796	intron_variant	FALSE	0.2439	8e-13	12.096910013008056	NA	0.03051591	[0.022-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2439	NA	0.03051591
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p22.3	6	22465392	intergenic	CASC15	NA	NA	ENSG00000272168	NA	NA	rs9393294-T	rs9393294	0	9393294	intron_variant	FALSE	0.1421	3e-10	9.522878745280337	NA	0.0327078	[0.023-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1421	NA	0.0327078
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p21.33	6	31540161	DDX39B, ATP6V1G2-DDX39B	ATP6V1G2-DDX39B, DDX39B, DDX39B, DDX39B, DDX39B, DDX39B, DDX39B, DDX39B	NA	NA	ENSG00000254870, ENSG00000230624, ENSG00000198563, ENSG00000235439, ENSG00000215425, ENSG00000229496, ENSG00000225073, ENSG00000225859	NA	NA	rs2269476-A	rs2269476	0	2269476	intron_variant	FALSE	0.179	2e-24	23.69897000433602	NA	0.04806173	[0.039-0.057] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.179	NA	0.04806173
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6q21	6	110396290	DDO	DDO	NA	NA	ENSG00000203797	NA	NA	rs2057149-T	rs2057149	0	2057149	intron_variant	FALSE	0.6487	8e-28	27.096910013008056	NA	0.04178947	[0.034-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.6487	NA	0.04178947
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6q22.31	6	118781108	RP11-210H10__A.1	SELENOKP3	NA	NA	ENSG00000225549	NA	NA	rs7743045-G	rs7743045	0	7743045	intron_variant	FALSE	0.6955	7e-9	8.154901959985743	NA	0.02275889	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.6955	NA	0.02275889
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6q24.1	6	139536204	intergenic	LINC01625 - ATP5PBP6	ENSG00000238099	ENSG00000219806	NA	61546	78234	rs35304300-G	rs35304300	0	35304300	intron_variant	TRUE	0.1966	1e-10	10	NA	0.02937207	[0.02-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1966	NA	0.02937207
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6q24.3	6	145673722	EPM2A	EPM2A	NA	NA	ENSG00000112425	NA	NA	rs80133860-T	rs80133860	0	80133860	intron_variant	FALSE	0.0322	8e-9	8.096910013008056	NA	0.06135084	[0.041-0.082] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0322	NA	0.06135084
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	7p22.1	7	6462736	KDELR2	DAGLB, KDELR2	NA	NA	ENSG00000164535, ENSG00000136240	NA	NA	rs6796-C	rs6796	0	6796	3_prime_UTR_variant	FALSE	0.2783	5e-15	14.301029995663981	NA	0.03154139	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2783	NA	0.03154139
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	7p21.1	7	16661173	BZW2	BZW2	NA	NA	ENSG00000136261	NA	NA	rs696279-A	rs696279	0	696279	intron_variant	FALSE	0.5321	7e-10	9.154901959985743	NA	0.02204623	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5321	NA	0.02204623
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	7p14.1	7	37412510	ELMO1	ELMO1	NA	NA	ENSG00000155849	NA	NA	rs11771053-T	rs11771053	0	11771053	intron_variant	FALSE	0.198	1e-11	11	NA	0.03095442	[0.022-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.198	NA	0.03095442
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	7p13	7	44833526	H2AFV	H2AZ2	NA	NA	ENSG00000105968	NA	NA	rs12155039-A	rs12155039	0	12155039	3_prime_UTR_variant	FALSE	0.4365	3e-11	10.522878745280337	NA	0.02415063	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4365	NA	0.02415063
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	21q21.3	21	26850773	Intergenic	ADAMTS1 - ADAMTS5	ENSG00000154734	ENSG00000154736	NA	5364	67149	rs229100-?	rs229100	0	229100	regulatory_region_variant	TRUE	NR	5e-6	5.301029995663981	NA	1.540832	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.540832	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	17p12	17	14404088	Intergenic	HS3ST3B1 - NA	ENSG00000125430	NA	NA	54684	NA	rs2323183-?	rs2323183	0	2323183	intron_variant	TRUE	NR	2e-8	7.698970004336019	NA	1.98	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.98	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	1q43	1	237163674	Intergenic	RYR2	NA	NA	ENSG00000198626	NA	NA	rs2490361-?	rs2490361	0	2490361	intron_variant	FALSE	NR	7e-6	5.154901959985743	NA	1.36	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.36	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	10q23.1	10	85333245	Intergenic	NA - LINC02647	NA	ENSG00000223993	NA	NA	45082	rs2642611-?	rs2642611	0	2642611	intergenic_variant	TRUE	NR	6e-6	5.221848749616356	NA	1.791	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.791	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	3q13.11	3	106490035	Intergenic	LINC00882	NA	NA	ENSG00000242759	NA	NA	rs2712475-?	rs2712475	0	2712475	intron_variant	FALSE	NR	7e-6	5.154901959985743	NA	1.5236934	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.5236934	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	15q21.3	15	56251348	Intergenic	TEX9	NA	NA	ENSG00000151575	NA	NA	rs2718930-?	rs2718930	0	2718930	intron_variant	FALSE	NR	8e-6	5.096910013008056	NA	1.4501159	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.4501159	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	6q16.3	6	104328779	Intergenic	NA	NA	NA	NA	NA	NA	rs274437-?	rs274437	0	274437	intergenic_variant	TRUE	NR	5e-6	5.301029995663981	NA	1.4566643	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.4566643	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	9p23	9	11664363	Intergenic	NA	NA	NA	NA	NA	NA	rs2821158-?	rs2821158	0	2821158	intron_variant	TRUE	NR	9e-7	6.045757490560675	NA	2.584	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	2.584	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	21q22.2	21	40888129	Intergenic	YRDCP3 - NA	ENSG00000230859	NA	NA	23656	NA	rs2837862-?	rs2837862	0	2837862	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	NA	1.589	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.589	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	8p23.3	8	1322504	Intergenic	DLGAP2, DLGAP2, DLGAP2	NA	NA	ENSG00000198010, ENSG00000282318, ENSG00000274161	NA	NA	rs28719689-?	rs28719689	0	28719689	intron_variant	FALSE	NR	4e-6	5.3979400086720375	NA	1.584	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.584	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	18q12.1	18	31213035	Intergenic	DSC1 - NA	ENSG00000134765	NA	NA	50179	NA	rs2920003-?	rs2920003	0	2920003	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	NA	1.719	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.719	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	6p22.1	6	29656335	Intergenic	SUMO2P1 - MOG	ENSG00000228130	ENSG00000137345	NA	19992	667	rs29234-?	rs29234	0	29234	regulatory_region_variant	TRUE	NR	2e-8	7.698970004336019	NA	2.219	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	2.219	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	8p23.2	8	3859946	Intergenic	CSMD1	NA	NA	ENSG00000183117	NA	NA	rs2930353-?	rs2930353	0	2930353	intron_variant	FALSE	NR	5e-6	5.301029995663981	NA	1.363	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.363	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	4p15.32	4	16911094	Intergenic	LDB2 - SCFD2	ENSG00000169744	ENSG00000184178	NA	12416	35961888	rs10012525-?	rs10012525	0	10012525	intergenic_variant	TRUE	NR	5e-6	5.301029995663981	NA	1.836	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.836	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	2p21	2	42192689	Intergenic	EML4	NA	NA	ENSG00000143924	NA	NA	rs10193935-?	rs10193935	0	10193935	intron_variant	FALSE	NR	1e-6	6	NA	1.532	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.532	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	7q21.11	7	78275813	Intergenic	MAGI2	NA	NA	ENSG00000187391	NA	NA	rs10485879-?	rs10485879	0	10485879	intron_variant	FALSE	NR	4e-7	6.3979400086720375	NA	1.5518312	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.5518312	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	2p24.2	2	18313189	KCNS3	KCNS3	NA	NA	ENSG00000170745	NA	NA	rs10495672-?	rs10495672	0	10495672	intron_variant	FALSE	NR	1e-6	6	NA	1.459854	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.459854	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	12q21.1	12	74972955	Intergenic	NA - KCNC2	NA	ENSG00000166006	NA	NA	67122	rs10506682-?	rs10506682	0	10506682	intergenic_variant	TRUE	NR	4e-7	6.3979400086720375	NA	1.554	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.554	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	13q22.1	13	74054545	Intergenic	KLF12	NA	NA	ENSG00000118922	NA	NA	rs10507824-?	rs10507824	0	10507824	intron_variant	FALSE	NR	4e-6	5.3979400086720375	NA	2.265	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	2.265	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	12q13.13	12	53293603	Intergenic	ESPL1	NA	NA	ENSG00000135476	NA	NA	rs1056692-?	rs1056692	0	1056692	3_prime_UTR_variant	FALSE	NR	5e-6	5.301029995663981	NA	1.37	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.37	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	9q33.1	9	117004503	Intergenic	ASTN2	NA	NA	ENSG00000148219	NA	NA	rs10817971-?	rs10817971	0	10817971	intron_variant	FALSE	NR	7e-6	5.154901959985743	NA	1.4070635	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.4070635	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	1q42.2	1	233106260	Intergenic	PCNX2	NA	NA	ENSG00000135749	NA	NA	rs10910660-?	rs10910660	0	10910660	intron_variant	FALSE	NR	5e-6	5.301029995663981	NA	1.4275517	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.4275517	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	11p14.3	11	25269469	Intergenic	NA	NA	NA	NA	NA	NA	rs11028546-?	rs11028546	0	11028546	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	NA	2.881	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	2.881	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	3p26.3	3	393460	Intergenic	CHL1	NA	NA	ENSG00000134121	NA	NA	rs11129766-?	rs11129766	0	11129766	intron_variant	FALSE	NR	2e-6	5.698970004336019	NA	2.797	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	2.797	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	11q22.3	11	108639955	Intergenic	EXPH5 - DDX10	ENSG00000110723	ENSG00000178105	NA	46187	25114	rs11212737-?	rs11212737	0	11212737	intergenic_variant	TRUE	NR	3e-7	6.522878745280337	NA	1.4236902	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.4236902	NA
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	9325848	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	38270	45242	rs9987289-A	rs9987289	0	9987289	non_coding_transcript_exon_variant	TRUE	NR	2e-45	44.69897000433602	NA	0.084	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.084
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	9326086	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	38508	45004	rs4841132-A	rs4841132	0	4841132	non_coding_transcript_exon_variant	TRUE	0.087	2e-35	34.69897000433602	(EA)	0.083	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.087	NA	0.083
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	9326086	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	38508	45004	rs4841132-A	rs4841132	0	4841132	non_coding_transcript_exon_variant	TRUE	0.161	4e-10	9.397940008672037	(Hispanic)	0.104	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.161	NA	0.104
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	9326086	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	38508	45004	rs4841132-A	rs4841132	0	4841132	non_coding_transcript_exon_variant	TRUE	NR	4e-47	46.39794000867204	NA	0.086	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.086
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	9327181	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	39603	43909	rs6601299-T	rs6601299	0	6601299	intron_variant	TRUE	0.096	1e-33	33	(EA)	0.077	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.096	NA	0.077
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	9327181	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	39603	43909	rs6601299-T	rs6601299	0	6601299	intron_variant	TRUE	0.196	6e-9	8.221848749616356	(Hispanic)	0.09	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.196	NA	0.09
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	9327181	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	39603	43909	rs6601299-T	rs6601299	0	6601299	intron_variant	TRUE	NR	3e-44	43.52287874528034	NA	0.079	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.079
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	9327636	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	40058	43454	rs2126259-T	rs2126259	0	2126259	intron_variant	TRUE	0.096	2e-33	32.69897000433602	(EA)	0.076	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.096	NA	0.076
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	9327636	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	40058	43454	rs2126259-T	rs2126259	0	2126259	intron_variant	TRUE	0.198	7e-9	8.154901959985743	(Hispanic)	0.089	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.198	NA	0.089
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	9327636	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	40058	43454	rs2126259-T	rs2126259	0	2126259	intron_variant	TRUE	NR	1e-43	43	NA	0.078	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.078
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p23.1	8	10634174	NR	RP1L1	NA	NA	ENSG00000183638	NA	NA	rs4455790-C	rs4455790	0	4455790	intron_variant	FALSE	NR	8e-7	6.096910013008056	NA	0.021	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.021
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19949120	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs7016529-T	rs7016529	0	7016529	intron_variant	FALSE	0.983	2e-25	24.69897000433602	(EA)	0.152	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.983	NA	0.152
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19949120	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs7016529-T	rs7016529	0	7016529	intron_variant	FALSE	NR	1e-22	22	NA	0.119	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.119
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19961928	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs326-A	rs326	0	326	intron_variant	FALSE	0.693	3e-96	95.52287874528034	(EA)	0.084	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.693	NA	0.084
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19961928	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs326-A	rs326	0	326	intron_variant	FALSE	0.696	1e-18	18	(Hispanic)	0.117	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.696	NA	0.117
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19961928	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs326-A	rs326	0	326	intron_variant	FALSE	0.802	1e-10	10	(East Asian)	0.108	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.802	NA	0.108
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19961928	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs326-A	rs326	0	326	intron_variant	FALSE	NR	2e-125	124.69897000433602	NA	0.088	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.088
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19966981	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs13702-T	rs13702	0	13702	3_prime_UTR_variant	FALSE	0.7	2e-111	110.69897000433602	(EA)	0.091	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.7	NA	0.091
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19966981	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs13702-T	rs13702	0	13702	3_prime_UTR_variant	FALSE	0.704	1e-16	16	(Hispanic)	0.111	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.704	NA	0.111
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19966981	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs13702-T	rs13702	0	13702	3_prime_UTR_variant	FALSE	0.803	1e-10	10	(East Asian)	0.109	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.803	NA	0.109
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19966981	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs13702-T	rs13702	0	13702	3_prime_UTR_variant	FALSE	NR	1e-139	139	NA	0.094	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.094
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19967156	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs15285-C	rs15285	0	15285	3_prime_UTR_variant	FALSE	0.7	1e-110	110	(EA)	0.091	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.7	NA	0.091
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19967156	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs15285-C	rs15285	0	15285	3_prime_UTR_variant	FALSE	0.705	1e-16	16	(Hispanic)	0.111	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.705	NA	0.111
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19967156	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs15285-C	rs15285	0	15285	3_prime_UTR_variant	FALSE	0.803	1e-10	10	(East Asian)	0.109	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.803	NA	0.109
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8p21.3	8	19967156	NR	LPL	NA	NA	ENSG00000175445	NA	NA	rs15285-C	rs15285	0	15285	3_prime_UTR_variant	FALSE	NR	3e-139	138.52287874528034	NA	0.094	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.094
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7p15.1	7	28144083	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs849140-T	rs849140	0	849140	intron_variant	FALSE	0.4168	3e-12	11.522878745280337	NA	0.0253	[0.018-0.032] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.4168	NA	0.0253
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.1	6	43790159	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	3672	54719	rs998584-A	rs998584	0	998584	regulatory_region_variant	TRUE	0.4672	3e-6	5.522878745280337	NA	0.0254	[0.015-0.036] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.4672	NA	0.0254
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12p11.22	12	28381482	CCDC91	CCDC91	NA	NA	ENSG00000123106	NA	NA	rs2638953-C	rs2638953	0	2638953	intron_variant	FALSE	0.6764	2e-12	11.698970004336019	NA	0.0258	[0.019-0.033] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.6764	NA	0.0258
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q22.2	3	134484505	ANAPC13, CEP63	ANAPC13	NA	NA	ENSG00000129055	NA	NA	rs6772896-T	rs6772896	0	6772896	intron_variant	FALSE	0.6799	1e-12	12	NA	0.026	[0.019-0.033] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.6799	NA	0.026
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q25.31	3	157079820	LEKR1	LEKR1 - LINC00880	ENSG00000197980	ENSG00000243629	NA	33691	1847	rs17451107-T	rs17451107	0	17451107	regulatory_region_variant	TRUE	0.6145	6e-13	12.221848749616356	NA	0.0263	[0.019-0.034] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.6145	NA	0.0263
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q22.33	15	67199963	SMAD3	SMAD3 - AAGAB	ENSG00000166949	ENSG00000103591	NA	4790	704	rs7166081-A	rs7166081	0	7166081	regulatory_region_variant	TRUE	0.7599	2e-10	9.698970004336019	NA	0.0266	[0.018-0.035] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.7599	NA	0.0266
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p36.22	1	10226118	KIF1B	KIF1B	NA	NA	ENSG00000054523	NA	NA	rs17396340-A	rs17396340	0	17396340	intron_variant	FALSE	0.132	1e-11	11	NA	0.027	[0.019-0.035] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.132	NA	0.027
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q16.3	6	104949543	LIN28B	LIN28B	NA	NA	ENSG00000187772	NA	NA	rs395962-T	rs395962	0	395962	intron_variant	FALSE	0.3169	3e-14	13.522878745280337	NA	0.0281	[0.021-0.035] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.3169	NA	0.0281
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q25.3	1	184051811	TSEN15	TSEN15	NA	NA	ENSG00000198860	NA	NA	rs2274432-A	rs2274432	0	2274432	missense_variant	FALSE	0.3486	3e-14	13.522878745280337	NA	0.0283	[0.021-0.036] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.3486	NA	0.0283
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q13.13	12	54034227	HOXC5	HOXC4, HOXC5	NA	NA	ENSG00000198353, ENSG00000172789	NA	NA	rs2071449-A	rs2071449	0	2071449	intron_variant	FALSE	0.3614	4e-14	13.397940008672037	NA	0.0292	[0.022-0.037] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.3614	NA	0.0292
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p21.2	3	51171215	DOCK3	DOCK3	NA	NA	ENSG00000088538	NA	NA	rs4378999-T	rs4378999	0	4378999	intron_variant	FALSE	0.119	8e-11	10.096910013008056	NA	0.03	[0.02-0.04] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.119	NA	0.03
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q35.3	5	177100576	FGFR4	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-T	rs6556301	0	6556301	intergenic_variant	TRUE	0.3605	4e-14	13.397940008672037	NA	0.0314	[0.023-0.039] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.3605	NA	0.0314
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118321979	SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126	NA	57490	292354	rs7536458-T	rs7536458	0	7536458	intergenic_variant	TRUE	0.748	2e-15	14.698970004336019	NA	0.0333	[0.025-0.042] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.748	NA	0.0333
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2p16.1	2	55869757	EFEMP1	EFEMP1	NA	NA	ENSG00000115380	NA	NA	rs3791679-A	rs3791679	0	3791679	intron_variant	FALSE	0.7555	5e-16	15.301029995663981	NA	0.0354	[0.027-0.044] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.7555	NA	0.0354
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118962811	TBX15, WARS2	TBX15	NA	NA	ENSG00000092607	NA	NA	rs10923712-A	rs10923712	0	10923712	intron_variant	FALSE	0.6025	2e-25	24.69897000433602	NA	0.0366	[0.03-0.043] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.6025	NA	0.0366
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9q22.32	9	95493953	PTCH1	PTCH1	NA	NA	ENSG00000185920	NA	NA	rs473902-T	rs473902	0	473902	intron_variant	FALSE	0.918	6e-8	7.221848749616356	NA	0.0413	[0.026-0.056] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.918	NA	0.0413
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16q22.1	16	67301066	KCTD19	KCTD19	NA	NA	ENSG00000168676	NA	NA	rs16957304-A	rs16957304	0	16957304	non_coding_transcript_exon_variant	FALSE	0.9298	8e-11	10.096910013008056	NA	0.0599	[0.042-0.078] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.9298	NA	0.0599
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9q31.1	9	104973639	ABCA1	CT70	NA	NA	ENSG00000230013	NA	NA	rs10991437-A	rs10991437	0	10991437	intron_variant	FALSE	0.1167	8e-8	7.096910013008056	NA	0.0294	[0.019-0.04] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.1167	NA	0.0294
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9q31.1	9	104973639	ABCA1	CT70	NA	NA	ENSG00000230013	NA	NA	rs10991437-A	rs10991437	0	10991437	intron_variant	FALSE	0.1167	3e-6	5.522878745280337	(women)	0.0341	[0.02-0.048] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.1167	NA	0.0341
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p14.1	3	64732582	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs2371767-C	rs2371767	0	2371767	intron_variant	FALSE	0.3027	1e-22	22	(women)	0.0515	[0.041-0.062] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.3027	NA	0.0515
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p14.1	3	64732582	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs2371767-C	rs2371767	0	2371767	intron_variant	FALSE	0.3027	5e-18	17.30102999566398	NA	0.035	[0.027-0.043] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.3027	NA	0.035
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q11.2	5	56510924	ANKRD55	RPL26P19 - C5orf67	ENSG00000226221	ENSG00000225940	NA	5852	643	rs459193-A	rs459193	0	459193	intergenic_variant	TRUE	0.2796	9e-13	12.045757490560675	NA	0.0278	[0.02-0.035] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.2796	NA	0.0278
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q11.2	5	56510924	ANKRD55	RPL26P19 - C5orf67	ENSG00000226221	ENSG00000225940	NA	5852	643	rs459193-A	rs459193	0	459193	intergenic_variant	TRUE	0.2796	2e-13	12.698970004336019	(men)	0.0429	[0.031-0.054] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.2796	NA	0.0429
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q13.12	3	107594133	BBX	BBX	NA	NA	ENSG00000114439	NA	NA	rs670752-A	rs670752	0	670752	intron_variant	FALSE	0.296	3e-10	9.522878745280337	(AA,women)	0.024	[0.016-0.032] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.296	NA	0.024
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	18q21.33	18	63178651	BCL2	BCL2	NA	NA	ENSG00000171791	NA	NA	rs12454712-T	rs12454712	0	12454712	intron_variant	FALSE	0.6153	7e-6	5.154901959985743	(women)	0.0304	[0.017-0.044] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.6153	NA	0.0304
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16q12.1	16	49830880	ZNF423	ZNF423	NA	NA	ENSG00000102935	NA	NA	rs2047937-T	rs2047937	0	2047937	intron_variant	FALSE	0.5057	4e-7	6.3979400086720375	NA	0.0176	[0.011-0.024] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.5057	NA	0.0176
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q26.3	15	100147762	ADAMTS17	ADAMTS17	NA	NA	ENSG00000140470	NA	NA	rs4246302-A	rs4246302	0	4246302	intron_variant	FALSE	0.6969	5e-6	5.301029995663981	NA	0.0173	[0.0099-0.0247] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.6969	NA	0.0173
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q14.3	12	65966384	HMGA2	HMGA2 - MIR6074	ENSG00000149948	ENSG00000276878	NA	93	57236	rs7970350-T	rs7970350	0	7970350	intergenic_variant	TRUE	0.497	8e-7	6.096910013008056	NA	0.0172	[0.01-0.024] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.497	NA	0.0172
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q22.3	7	105115908	SRPK2	SRPK2	NA	NA	ENSG00000135250	NA	NA	rs1144-T	rs1144	0	1144	intron_variant	FALSE	0.6579	5e-6	5.301029995663981	NA	0.0165	[0.0094-0.0236] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.6579	NA	0.0165
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	20q13.13	20	48914749	ARFGEF2	PREX1 - ARFGEF2	ENSG00000124126	ENSG00000124198	NA	86750	6962	rs6012558-A	rs6012558	0	6012558	intergenic_variant	TRUE	0.412	2e-9	8.698970004336019	NA	0.016	[0.01-0.022] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.412	NA	0.016
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	10q24.32	10	102567827	SUFU	SUFU	NA	NA	ENSG00000107882	NA	NA	rs3862030-A	rs3862030	0	3862030	intron_variant	FALSE	0.5599	1e-6	6	NA	0.0164	[0.0097-0.0231] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.5599	NA	0.0164
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q35.2	5	173921153	CPEB4	CPEB4	NA	NA	ENSG00000113742	NA	NA	rs10516107-A	rs10516107	0	10516107	intron_variant	FALSE	0.3058	8e-6	5.096910013008056	NA	0.017	[0.0096-0.0244] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.3058	NA	0.017
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2q37.3	2	241297557	HDLBP	HDLBP	NA	NA	ENSG00000115677	NA	NA	rs6743226-C	rs6743226	0	6743226	intron_variant	FALSE	0.543	7e-12	11.154901959985743	NA	0.018	[0.012-0.024] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.543	NA	0.018
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q41	1	221136075	HLX	NA	NA	NA	NA	NA	NA	rs12127195-A	rs12127195	0	12127195	intergenic_variant	TRUE	0.3148	1e-6	6	NA	0.0181	[0.011-0.025] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.3148	NA	0.0181
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.31	6	35037307	ANKS1A	ANKS1A	NA	NA	ENSG00000064999	NA	NA	rs13210323-A	rs13210323	0	13210323	intron_variant	FALSE	0.7176	2e-6	5.698970004336019	NA	0.0183	[0.011-0.026] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.7176	NA	0.0183
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2p22.3	2	33154196	LTBP1	LTBP1	NA	NA	ENSG00000049323	NA	NA	rs6715793-T	rs6715793	0	6715793	intron_variant	FALSE	0.4858	2e-7	6.698970004336019	NA	0.0185	[0.011-0.026] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.4858	NA	0.0185
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q21.2	7	92624658	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs10269774-A	rs10269774	0	10269774	intron_variant	FALSE	0.333	3e-10	9.522878745280337	NA	0.019	[0.013-0.025] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.333	NA	0.019
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	19p13.11	19	18278325	JUND	IQCN - JUND	ENSG00000130518	ENSG00000130522	NA	3816	1369	rs12608504-A	rs12608504	0	12608504	regulatory_region_variant	TRUE	0.3589	3e-8	7.522878745280337	NA	0.0208	[0.014-0.028] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.3589	NA	0.0208
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q21.3	5	108816727	FER	FER	NA	NA	ENSG00000151422	NA	NA	rs10041657-A	rs10041657	0	10041657	intron_variant	FALSE	0.2268	2e-7	6.698970004336019	NA	0.021	[0.013-0.029] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.2268	NA	0.021
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q24.31	12	123920171	DNAH10	CCDC92, DNAH10	NA	NA	ENSG00000119242, ENSG00000197653	NA	NA	rs12317176-T	rs12317176	0	12317176	intron_variant	FALSE	0.649	4e-9	8.397940008672037	NA	0.0211	[0.014-0.028] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.649	NA	0.0211
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q22.33	6	127131790	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs2745353-T	rs2745353	0	2745353	intron_variant	FALSE	0.5202	6e-10	9.221848749616356	NA	0.0215	[0.015-0.028] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.5202	NA	0.0215
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p22.2	6	26267527	HIST1H3G, HIST1H2BH	H2BC9 - H3C8	ENSG00000275713	ENSG00000273983	NA	13817	1878	rs7773004-A	rs7773004	0	7773004	intergenic_variant	TRUE	0.4885	5e-11	10.301029995663981	NA	0.0225	[0.016-0.029] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.4885	NA	0.0225
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7p15.2	7	27184152	HOXA11	HOXA11	NA	NA	ENSG00000005073	NA	NA	rs7801581-T	rs7801581	0	7801581	intron_variant	FALSE	0.2502	9e-8	7.045757490560675	NA	0.0228	[0.014-0.031] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.2502	NA	0.0228
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	20p12.3	20	6632185	BMP2	NA - LINC01713	NA	ENSG00000228482	NA	NA	98895	rs1884897-A	rs1884897	0	1884897	regulatory_region_variant	TRUE	0.3739	7e-10	9.154901959985743	NA	0.0229	[0.016-0.03] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.3739	NA	0.0229
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9q31.2	9	106128240	TMEM38B	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs9408815-C	rs9408815	0	9408815	intron_variant	FALSE	0.75	1e-11	11	NA	0.023	[0.017-0.029] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.75	NA	0.023
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	19p13.2	19	8577276	ADAMTS10	MYO1F	NA	NA	ENSG00000142347	NA	NA	rs4542783-T	rs4542783	0	4542783	non_coding_transcript_exon_variant	FALSE	0.543	1e-8	8	NA	0.0231	[0.015-0.031] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.543	NA	0.0231
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	4q13.3	4	72649596	ADAMTS3	ADAMTS3 - HNRNPA1P67	ENSG00000156140	ENSG00000270665	NA	80375	157671	rs7697556-T	rs7697556	0	7697556	intergenic_variant	TRUE	0.486	5e-19	18.30102999566398	NA	0.024	[0.018-0.03] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.486	NA	0.024
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8q24.21	8	129724451	GSDMC	CCDC26 - MTRF1LP2	ENSG00000229140	ENSG00000224110	NA	40681	4293	rs6470765-A	rs6470765	0	6470765	intergenic_variant	TRUE	0.777	3e-12	11.522878745280337	NA	0.024	[0.018-0.03] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.777	NA	0.024
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q36.1	7	148932667	EZH2	RN7SL569P - RNY4	ENSG00000239468	ENSG00000252316	NA	42154	30648	rs822531-T	rs822531	0	822531	intergenic_variant	TRUE	0.7837	5e-7	6.301029995663981	NA	0.0241	[0.015-0.034] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.7837	NA	0.0241
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2p23.3	2	25263901	DNMT3A	DNMT3A	NA	NA	ENSG00000119772	NA	NA	rs12991495-T	rs12991495	0	12991495	intron_variant	FALSE	0.6973	3e-10	9.522878745280337	NA	0.0253	[0.017-0.033] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004500	Genome-wide genotyping array	0.6973	NA	0.0253
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	10q21.2	10	62622599	ZNF365	NA	NA	NA	NA	NA	NA	rs2893907-C	rs2893907	0	2893907	intron_variant	TRUE	0.58	2e-9	8.698970004336019	NA	1.031	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.58	1.031	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	10q24.32	10	102466075	C10orf95, ACTR1A	ACTR1A, MFSD13A	NA	NA	ENSG00000138107, ENSG00000138111	NA	NA	rs10883723-C	rs10883723	0	10883723	5_prime_UTR_variant	FALSE	0.31	2e-8	7.698970004336019	NA	1.03	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.31	1.03	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	5q31.3	5	141545795	DIAPH1	DIAPH1	NA	NA	ENSG00000131504	NA	NA	rs740474-C	rs740474	0	740474	intron_variant	FALSE	0.42	6e-11	10.221848749616356	NA	1.034	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.42	1.034	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	5q33.3	5	160482338	MIR3142, MIR146A	MIR3142HG	NA	NA	ENSG00000253522	NA	NA	rs2910162-G	rs2910162	0	2910162	intron_variant	FALSE	0.68	3e-9	8.522878745280337	NA	1.033	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.68	1.033	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	6p21.32	6	32658626	HLA-DQA1, HLA-DQB1	HLA-DQA1 - HLA-DQB1	ENSG00000196735	ENSG00000206237	NA	11564	841	rs34004019-A	rs34004019	0	34004019	regulatory_region_variant	TRUE	0.7	4e-52	51.39794000867204	NA	1.101	[1.09-1.11]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.7	1.101	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	6p21.33	6	31355235	HLA-B	MIR6891, HLA-B, HLA-B, HLA-B, HLA-B, HLA-B, HLA-B	NA	NA	ENSG00000277402, ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000232126, ENSG00000224608, ENSG00000206450	NA	NA	rs2854001-A	rs2854001	0	2854001	non_coding_transcript_exon_variant	FALSE	0.18	1e-19	19	NA	1.059	[1.05-1.07]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.18	1.059	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	6p22.1	6	29925798	HLA-J	MCCD1P1 - HCG4B	ENSG00000229411	ENSG00000236033	NA	17153	185	rs9259819-G	rs9259819	0	9259819	intron_variant	TRUE	0.5	2e-9	8.698970004336019	NA	1.036	[1.02-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.5	1.036	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	6p21.33	6	31606748	NCR3, AIF1	NCR3 - UQCRHP1	ENSG00000237808	ENSG00000229189	NA	13742	4335	rs28895016-C	rs28895016	0	28895016	intergenic_variant	TRUE	0.91	9e-16	15.045757490560675	NA	1.097	[1.07-1.12]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.91	1.097	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	6q15	6	90277793	BACH2	BACH2	NA	NA	ENSG00000112182	NA	NA	rs2134814-C	rs2134814	0	2134814	intron_variant	FALSE	0.65	2e-17	16.69897000433602	NA	1.046	[1.04-1.06]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.65	1.046	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	6q21	6	106219660	ATG5	ATG5	NA	NA	ENSG00000057663	NA	NA	rs9372120-G	rs9372120	0	9372120	intron_variant	FALSE	0.18	4e-11	10.397940008672037	NA	1.042	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.18	1.042	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	6q23.3	6	137874014	TNFAIP3	TNFAIP3	NA	NA	ENSG00000118503	NA	NA	rs5029937-G	rs5029937	0	5029937	intron_variant	FALSE	0.97	2e-8	7.698970004336019	NA	1.081	[1.05-1.11]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.97	1.081	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	6q25.3	6	157098374	ARID1B	ARID1B	NA	NA	ENSG00000049618	NA	NA	rs9383820-C	rs9383820	0	9383820	intron_variant	FALSE	0.76	1e-8	8	NA	1.037	[1.02-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.76	1.037	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	7p21.1	7	20521373	ITGB8, ABCB5	ITGB8 - EEF1A1P27	ENSG00000105855	ENSG00000179460	NA	105619	60699	rs6461503-T	rs6461503	0	6461503	intergenic_variant	TRUE	0.53	2e-14	13.698970004336019	NA	1.039	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.53	1.039	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	7p21.1	7	20336395	ITGB8	ITGB8	NA	NA	ENSG00000105855	NA	NA	rs10486391-A	rs10486391	0	10486391	intron_variant	FALSE	0.53	7e-9	8.154901959985743	NA	1.03	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.53	1.03	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	7p12.2	7	50214301	C7orf72, IKZF1	SPATA48 - IKZF1	ENSG00000164500	ENSG00000185811	NA	55045	89767	rs17664743-A	rs17664743	0	17664743	intron_variant	TRUE	0.2	6e-11	10.221848749616356	NA	1.042	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.2	1.042	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	7q11.23	7	77389225	GSAP	GSAP	NA	NA	ENSG00000186088	NA	NA	rs4296977-C	rs4296977	0	4296977	intron_variant	FALSE	0.16	2e-13	12.698970004336019	NA	1.055	[1.04-1.07]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.16	1.055	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	8q24.21	8	127801845	MYC	PVT1	NA	NA	ENSG00000249859	NA	NA	rs6990534-A	rs6990534	0	6990534	intron_variant	FALSE	0.36	6e-14	13.221848749616356	NA	1.042	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.36	1.042	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	9p24.1	9	6208030	RANBP6, IL33	GTF3AP1 - IL33	ENSG00000237274	ENSG00000137033	NA	10782	7756	rs144829310-T	rs144829310	0	144829310	intergenic_variant	TRUE	0.16	1e-35	35	NA	1.09	[1.08-1.1]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.16	1.09	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	9p24.1	9	5064193	JAK2	JAK2	NA	NA	ENSG00000096968	NA	NA	rs16922576-C	rs16922576	0	16922576	intron_variant	FALSE	0.32	3e-10	9.522878745280337	NA	1.036	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.32	1.036	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	9q33.2	9	120888256	PHF19, TRAF1	PHF19	NA	NA	ENSG00000119403	NA	NA	rs10760123-T	rs10760123	0	10760123	intron_variant	FALSE	0.38	5e-9	8.301029995663981	NA	1.032	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.38	1.032	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	11q13.5	11	76582714	WNT11, LRRC32	EMSY - LINC02757	ENSG00000158636	ENSG00000255363	NA	29689	25139	rs7936323-A	rs7936323	0	7936323	intergenic_variant	TRUE	0.46	2e-63	62.69897000433602	NA	1.088	[1.08-1.1]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.46	1.088	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	11q21	11	95692362	SESN3, FAM76B	NA - FAM76B	NA	ENSG00000077458	NA	NA	76591	rs59593577-C	rs59593577	0	59593577	intron_variant	TRUE	0.87	2e-11	10.698970004336019	NA	1.053	[1.04-1.07]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.87	1.053	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	11q23.3	11	118872577	DDX6, CXCR5	Y_RNA - CXCR5	ENSG00000199964	ENSG00000160683	NA	36466	11315	rs12365699-G	rs12365699	0	12365699	regulatory_region_variant	TRUE	0.85	5e-18	17.30102999566398	NA	1.061	[1.05-1.07]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.85	1.061	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	11q24.3	11	128288294	KIRREL3-AS3, ETS1	LINC02098 - NA	ENSG00000272575	NA	NA	46853	NA	rs56129466-A	rs56129466	0	56129466	intergenic_variant	TRUE	0.79	2e-13	12.698970004336019	NA	1.047	[1.04-1.06]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.79	1.047	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	12q13.11	12	47803199	HDAC7	HDAC7	NA	NA	ENSG00000061273	NA	NA	rs55726902-G	rs55726902	0	55726902	intron_variant	FALSE	0.8	3e-16	15.522878745280337	NA	1.051	[1.04-1.06]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.8	1.051	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	12q13.12	12	49951888	AQP2	AQP2	NA	NA	ENSG00000167580	NA	NA	rs11169225-A	rs11169225	0	11169225	intron_variant	FALSE	0.18	1e-11	11	NA	1.045	[1.03-1.06]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.18	1.045	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	12q13.3	12	57095926	STAT6	STAT6	NA	NA	ENSG00000166888	NA	NA	rs1059513-T	rs1059513	0	1059513	3_prime_UTR_variant	FALSE	0.89	1e-22	22	NA	1.084	[1.07-1.1]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.89	1.084	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	12q13.2	12	56007301	SUOX, IKZF4	SUOX - IKZF4	ENSG00000139531	ENSG00000123411	NA	660	358	rs10876864-G	rs10876864	0	10876864	TF_binding_site_variant	TRUE	0.39	1e-19	19	NA	1.047	[1.04-1.06]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.39	1.047	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	12q24.12	12	111494996	ATXN2	ATXN2	NA	NA	ENSG00000204842	NA	NA	rs7137828-T	rs7137828	0	7137828	intron_variant	FALSE	0.54	2e-10	9.698970004336019	NA	1.033	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.54	1.033	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	NA	NA	NA	SPPL3, HNF1A-AS1	NA	NA	NA	NA	NA	NA	rs6489785-T	rs6489785	0	6489785	intergenic_variant	TRUE	0.37	2e-15	14.698970004336019	NA	1.043	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.37	1.043	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	12q24.31	12	123258146	C12orf65, CDK2AP1	CDK2AP1	NA	NA	ENSG00000111328	NA	NA	rs63406760-T	rs63406760	0	63406760	intron_variant	FALSE	0.77	3e-13	12.522878745280337	NA	1.047	[1.03-1.06]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.77	1.047	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	13q14.11	13	40599271	FOXO1	FOXO1	NA	NA	ENSG00000150907	NA	NA	rs4943794-C	rs4943794	0	4943794	intron_variant	FALSE	0.23	7e-12	11.154901959985743	NA	1.043	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.23	1.043	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	13q22.1	13	73053137	PIBF1, KLF5	PSMD10P3 - KLF5	ENSG00000232041	ENSG00000102554	NA	16289	1839	rs9573092-A	rs9573092	0	9573092	intergenic_variant	TRUE	0.7	3e-8	7.522878745280337	NA	1.03	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.7	1.03	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	14q13.2	14	35292469	PSMA6	PSMA6	NA	NA	ENSG00000100902	NA	NA	rs1048990-G	rs1048990	0	1048990	5_prime_UTR_variant	FALSE	0.16	1e-8	8	NA	1.039	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.16	1.039	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	14q21.1	14	37627797	FOXA1, TTC6	TTC6	NA	NA	ENSG00000139865	NA	NA	rs111914382-TG	rs111914382	0	111914382	intron_variant	FALSE	0.27	8e-9	8.096910013008056	NA	1.036	[1.02-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.27	1.036	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	14q24.1	14	68287700	RAD51B	RAD51B	NA	NA	ENSG00000182185	NA	NA	rs2104047-T	rs2104047	0	2104047	intron_variant	FALSE	0.36	2e-13	12.698970004336019	NA	1.042	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.36	1.042	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	14q24.3	14	75502265	JDP2, BATF	JDP2 - BATF	ENSG00000140044	ENSG00000156127	NA	28154	20190	rs9323612-A	rs9323612	0	9323612	intergenic_variant	TRUE	0.7	9e-9	8.045757490560675	NA	1.032	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.7	1.032	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	14q32.32	14	102768675	RCOR1, TRAF3	RCOR1 - TRAF3	ENSG00000089902	ENSG00000131323	NA	38114	8774	rs9989163-A	rs9989163	0	9989163	TF_binding_site_variant	TRUE	0.49	2e-8	7.698970004336019	NA	1.029	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.49	1.029	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	15q15.1	15	41490486	RTF1, ITPKA	RTF1 - ITPKA	ENSG00000137815	ENSG00000137825	NA	6923	2907	rs12440045-C	rs12440045	0	12440045	TF_binding_site_variant	TRUE	0.55	5e-10	9.301029995663981	NA	1.033	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.55	1.033	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	15q22.2	15	60776148	RORA	RORA	NA	NA	ENSG00000069667	NA	NA	rs10519067-G	rs10519067	0	10519067	intron_variant	FALSE	0.86	9e-13	12.045757490560675	NA	1.055	[1.04-1.07]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.86	1.055	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	15q22.33	15	67156025	SMAD3	SMAD3	NA	NA	ENSG00000166949	NA	NA	rs56375023-A	rs56375023	0	56375023	intron_variant	FALSE	0.21	8e-32	31.096910013008056	NA	1.073	[1.06-1.08]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.21	1.073	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	15q26.1	15	90502176	IQGAP1	IQGAP1	NA	NA	ENSG00000140575	NA	NA	rs3540-G	rs3540	0	3540	3_prime_UTR_variant	FALSE	0.65	3e-11	10.522878745280337	NA	1.036	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.65	1.036	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	16p13.13	16	11183501	CLEC16A, RMI2	CLEC16A - HNRNPCP4	ENSG00000038532	ENSG00000263179	NA	1315	59152	rs11644510-C	rs11644510	0	11644510	regulatory_region_variant	TRUE	0.64	6e-38	37.221848749616356	NA	1.072	[1.06-1.08]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.64	1.072	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	16p13.13	16	11397150	RMI2, LITAF	RMI2 - NA	ENSG00000175643	NA	NA	15488	NA	rs12596613-C	rs12596613	0	12596613	intron_variant	TRUE	0.67	6e-9	8.221848749616356	NA	1.032	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.67	1.032	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	17p13.2	17	4618178	SMTNL2, ALOX15	LINC01996 - RNU6-955P	ENSG00000261863	ENSG00000222429	NA	528	1571	rs71368508-C	rs71368508	0	71368508	regulatory_region_variant	TRUE	0.99	2e-9	8.698970004336019	NA	1.124	[1.09-1.16]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.99	1.124	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	17q21.1	17	39912823	GSDMB	GSDMB	NA	NA	ENSG00000073605	NA	NA	rs921650-A	rs921650	0	921650	intron_variant	FALSE	0.48	6e-30	29.221848749616356	NA	1.059	[1.05-1.07]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.48	1.059	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	17q21.2	17	40608272	CCR7, SMARCE1	CCR7 - SMARCE1	ENSG00000126353	ENSG00000073584	NA	42800	16690	rs112401631-A	rs112401631	0	112401631	TF_binding_site_variant	TRUE	0.01	2e-26	25.69897000433602	NA	1.26	[1.22-1.3]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.01	1.26	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	17q21.2	17	42262844	STAT5B	STAT5B	NA	NA	ENSG00000173757	NA	NA	rs7207591-A	rs7207591	0	7207591	intron_variant	FALSE	0.76	1e-9	9	NA	1.038	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.76	1.038	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	17q21.31	17	45353330	MAP3K14, ARHGAP27	RNA5SP443 - ARHGAP27	ENSG00000199953	ENSG00000159314	NA	25833	40572	rs7214661-G	rs7214661	0	7214661	regulatory_region_variant	TRUE	0.32	1e-8	8	NA	1.032	[1.02-1.04]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.32	1.032	NA
2017-12-05	29083406	Ferreira MA	2017-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29083406	Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.	Allergic disease (asthma, hay fever or eczema)	180,129 European ancestry cases, 180,709 European ancestry controls	NA	17q21.33	17	49320708	ZNF652	ZNF652	NA	NA	ENSG00000198740	NA	NA	rs9889262-A	rs9889262	0	9889262	intron_variant	FALSE	0.35	1e-15	15	NA	1.043	[1.03-1.05]	Affymetrix, Illumina [8307659] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST005038	Genome-wide genotyping array	0.35	1.043	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	9q34.13	9	132989126	GFI1B	GFI1B	NA	NA	ENSG00000165702	NA	NA	rs150813342-T	rs150813342	0	150813342	synonymous_variant	FALSE	0.0079	2e-107	106.69897000433602	NA	0.4683289	[0.43-0.51] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0079	NA	0.4683289
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	9q34.2	9	134056342	BRD3, RP11-374P20.4	BRD3	NA	NA	ENSG00000169925	NA	NA	rs2157770-G	rs2157770	0	2157770	intron_variant	FALSE	0.286	2e-28	27.69897000433602	NA	0.04436646	[0.037-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.286	NA	0.04436646
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	9q34.2	9	134077014	RP11-349K21.1	BRD3 - ARF4P1	ENSG00000169925	ENSG00000271525	NA	8479	1890	rs10821556-A	rs10821556	0	10821556	intergenic_variant	TRUE	0.3291	2e-39	38.69897000433602	NA	0.05072114	[0.043-0.058] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3291	NA	0.05072114
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	10p14	10	11794093	intergenic	ECHDC3 - PROSER2	ENSG00000134463	ENSG00000148426	NA	30023	29246	rs118033845-A	rs118033845	0	118033845	TF_binding_site_variant	TRUE	0.0356	6e-12	11.221848749616356	NA	0.06951009	[0.05-0.089] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0356	NA	0.06951009
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	10p14	10	11853098	PROSER2-AS1, PROSER2	PROSER2-AS1, PROSER2	NA	NA	ENSG00000225778, ENSG00000148426	NA	NA	rs11593377-C	rs11593377	0	11593377	intron_variant	FALSE	0.205	5e-18	17.30102999566398	NA	0.03885261	[0.03-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.205	NA	0.03885261
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	10q21.3	10	63306426	JMJD1C	JMJD1C	NA	NA	ENSG00000171988	NA	NA	rs10761741-T	rs10761741	0	10761741	intron_variant	FALSE	0.4182	5e-287	286.30102999566395	NA	0.1326053	[0.13-0.14] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4182	NA	0.1326053
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	10q23.33	10	95294018	PDLIM1	PDLIM1 - SORBS1	ENSG00000107438	ENSG00000095637	NA	3006	17753	rs1328599-T	rs1328599	0	1328599	intergenic_variant	TRUE	0.9227	3e-14	13.522878745280337	NA	0.05176265	[0.038-0.065] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.9227	NA	0.05176265
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	10q24.31	10	100315722	PKD2L1	PKD2L1	NA	NA	ENSG00000107593	NA	NA	rs603424-A	rs603424	0	603424	intron_variant	FALSE	0.1731	5e-31	30.30102999566398	NA	0.05547052	[0.046-0.065] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1731	NA	0.05547052
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	10q25.2	10	112391369	ACSL5	ACSL5	NA	NA	ENSG00000197142	NA	NA	rs35383388-CA	rs35383388	0	35383388	intron_variant	FALSE	0.7626	1e-24	24	NA	0.04572568	[0.037-0.054] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.7626	NA	0.04572568
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	10q25.2	10	112394994	ACSL5	ACSL5	NA	NA	ENSG00000197142	NA	NA	rs146605626-A	rs146605626	0	146605626	synonymous_variant	FALSE	0.0252	1e-11	11	NA	0.08147689	[0.058-0.105] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0252	NA	0.08147689
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	10q26.11	10	119250744	GRK5	GRK5	NA	NA	ENSG00000198873	NA	NA	rs10886430-G	rs10886430	0	10886430	intron_variant	FALSE	0.1289	7e-18	17.154901959985743	NA	0.04829004	[0.037-0.059] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1289	NA	0.04829004
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	10q26.13	10	124679797	FAM53B, RP11-12J10.3	FAM53B	NA	NA	ENSG00000189319	NA	NA	rs1998418-T	rs1998418	0	1998418	intron_variant	FALSE	0.819	8e-9	8.096910013008056	NA	0.02710538	[0.018-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.819	NA	0.02710538
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11p15.5	11	193863	SCGB1C1	SCGB1C1, BET1L	NA	NA	ENSG00000188076, ENSG00000177951	NA	NA	rs2294081-C	rs2294081	0	2294081	stop_gained	FALSE	0.4738	9e-106	105.04575749056067	NA	0.07995839	[0.073-0.087] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4738	NA	0.07995839
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11p15.5	11	196944	ODF3	BET1L, ODF3	NA	NA	ENSG00000177951, ENSG00000177947	NA	NA	rs11604127-T	rs11604127	0	11604127	5_prime_UTR_variant	FALSE	0.2361	7e-163	162.15490195998575	NA	0.1163212	[0.11-0.12] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2361	NA	0.1163212
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11p15.5	11	838722	CD151	POLR2L, CD151	NA	NA	ENSG00000177700, ENSG00000177697	NA	NA	rs6762-C	rs6762	0	6762	3_prime_UTR_variant	FALSE	0.2502	8e-9	8.096910013008056	NA	0.02411371	[0.016-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2502	NA	0.02411371
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11p15.4	11	3865946	STIM1	STIM1	NA	NA	ENSG00000167323	NA	NA	rs11030122-G	rs11030122	0	11030122	intron_variant	FALSE	0.3016	5e-11	10.301029995663981	NA	0.02614956	[0.018-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3016	NA	0.02614956
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11p15.4	11	5669314	TRIM5	TRIM5	NA	NA	ENSG00000132256	NA	NA	rs12271225-T	rs12271225	0	12271225	intron_variant	FALSE	0.1388	2e-12	11.698970004336019	NA	0.03671394	[0.026-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1388	NA	0.03671394
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11p15.4	11	5679844	TRIM5	TRIM5	NA	NA	ENSG00000132256	NA	NA	rs11601507-A	rs11601507	0	11601507	missense_variant	FALSE	0.0699	6e-19	18.221848749616356	NA	0.06304979	[0.049-0.077] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0699	NA	0.06304979
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11p15.4	11	5680179	TRIM5	TRIM5	NA	NA	ENSG00000132256	NA	NA	rs3824949-C	rs3824949	0	3824949	5_prime_UTR_variant	FALSE	0.557	6e-24	23.221848749616356	NA	0.03697798	[0.03-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.557	NA	0.03697798
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11p15.4	11	10686942	MRVI1	IRAG1	NA	NA	ENSG00000072952	NA	NA	rs719152-G	rs719152	0	719152	intron_variant	FALSE	0.2947	5e-15	14.301029995663981	NA	0.0312563	[0.023-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2947	NA	0.0312563
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11q12.2	11	61813978	FADS1, FADS2	FADS2, FADS1	NA	NA	ENSG00000134824, ENSG00000149485	NA	NA	rs7394579-G	rs7394579	0	7394579	intron_variant	FALSE	0.278	3e-33	32.52287874528034	NA	0.04847727	[0.041-0.056] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.278	NA	0.04847727
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11q13.1	11	65613445	MAP3K11	MAP3K11	NA	NA	ENSG00000173327	NA	NA	rs2004649-A	rs2004649	0	2004649	synonymous_variant	FALSE	0.4249	7e-20	19.154901959985743	NA	0.03334444	[0.026-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4249	NA	0.03334444
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11q13.4	11	72790175	STARD10, ARAP1	ARAP1, STARD10	NA	NA	ENSG00000186635, ENSG00000214530	NA	NA	rs56133113-G	rs56133113	0	56133113	intron_variant	FALSE	0.1187	7e-15	14.154901959985743	NA	0.04351674	[0.033-0.054] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1187	NA	0.04351674
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11q13.4	11	73236889	RP11-800A3.4	P2RY2	NA	NA	ENSG00000175591	NA	NA	rs11235688-A	rs11235688	0	11235688	3_prime_UTR_variant	FALSE	0.4175	5e-11	10.301029995663981	NA	0.02417698	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4175	NA	0.02417698
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	11q21	11	95095304	ENDOD1	ENDOD1	NA	NA	ENSG00000149218	NA	NA	rs10605167-T	rs10605167	0	10605167	intron_variant	FALSE	0.7825	6e-20	19.221848749616356	NA	0.03997559	[0.031-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.7825	NA	0.03997559
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4q21.1	4	75936156	NAAA, CXCL9, ART3, CXCL11, SDAD1, AC110615.1, RP11-630D6.5, AC112719.2, RP11-630D6.1	NAAA	NA	NA	ENSG00000138744	NA	NA	rs4859571-T	rs4859571	0	4859571	missense_variant	FALSE	0.2402207	1e-46	46	(N-acylethanolamine-hydrolyzing acid amidase)	0.7054	[0.61-0.8] unit decrease	Affymetrix [509946]	N	N-acylethanolamine-hydrolyzing acid amidase measurement	http://www.ebi.ac.uk/efo/EFO_0008240	GCST004365	Genome-wide genotyping array	0.2402207	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q23.3	1	160752760	SLAMF7	SLAMF7	NA	NA	ENSG00000026751	NA	NA	rs489286-A	rs489286	0	489286	intron_variant	FALSE	0.3458835	2e-57	56.69897000433602	(SLAM family member 7)	0.6907	[0.61-0.77] unit decrease	Affymetrix [509946]	N	SLAM family member 7 measurement	http://www.ebi.ac.uk/efo/EFO_0008287	GCST004365	Genome-wide genotyping array	0.3458835	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q24.2	1	168738519	DPT, AL049798.1, RP1-10C16.1	DPT - LINC00626	ENSG00000143196	ENSG00000225826	NA	9313	45493	rs494189-A	rs494189	0	494189	intron_variant	TRUE	0.2467402	1e-14	14	(Dermatopontin)	0.3546	[0.27-0.44] unit decrease	Affymetrix [509946]	N	dermatopontin measurement	http://www.ebi.ac.uk/efo/EFO_0008108	GCST004365	Genome-wide genotyping array	0.2467402	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q32.1	1	203213164	CHIT1	CHIT1	NA	NA	ENSG00000133063	NA	NA	rs4950937-A	rs4950937	0	4950937	intron_variant	FALSE	0.2730924	1e-24	24	(Chitotriosidase-1)	0.4856	[0.4-0.58] unit increase	Affymetrix [509946]	N	chitotriosidase-1 measurement	http://www.ebi.ac.uk/efo/EFO_0008084	GCST004365	Genome-wide genotyping array	0.2730924	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q32.1	1	205084091	CNTN2, RBBP5, DSTYK, TMEM81, RP11-383G10.5, RP11-536L3.4, RP11-383G10.1, TMCC2	TMEM81	NA	NA	ENSG00000174529	NA	NA	rs4951168-C	rs4951168	0	4951168	missense_variant	FALSE	0.1465257	2e-39	38.69897000433602	(Contactin-2)	0.7847	[0.67-0.9] unit increase	Affymetrix [509946]	N	contactin-2 measurement	http://www.ebi.ac.uk/efo/EFO_0008100	GCST004365	Genome-wide genotyping array	0.1465257	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	16p13.3	16	1247515	TPSD1, TPSG1, TPSB2, TPSAB1, RP11-616M22.5, CACNA1H, RP11-616M22.12, PRSS29P	TPSAB1 - TPSD1	ENSG00000172236	ENSG00000095917	NA	4961	8544	rs4984778-C	rs4984778	0	4984778	intergenic_variant	TRUE	0.2846386	3e-27	26.522878745280337	(Tryptase beta-2)	0.5167	[0.43-0.61] unit increase	Affymetrix [509946]	N	tryptase beta-2 measurement	http://www.ebi.ac.uk/efo/EFO_0008306	GCST004365	Genome-wide genotyping array	0.2846386	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q27.3	3	186736391	KNG1, RP11-573D15.8	KNG1	NA	NA	ENSG00000113889	NA	NA	rs5030062-C	rs5030062	0	5030062	non_coding_transcript_exon_variant	FALSE	0.3850402	3e-40	39.52287874528034	(Coagulation Factor XI)	0.5581	[0.48-0.64] unit increase	Affymetrix [509946]	N	factor XI measurement	http://www.ebi.ac.uk/efo/EFO_0004694	GCST004365	Genome-wide genotyping array	0.3850402	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q27.3	3	186736391	KNG1, RP11-573D15.8	KNG1	NA	NA	ENSG00000113889	NA	NA	rs5030062-C	rs5030062	0	5030062	non_coding_transcript_exon_variant	FALSE	0.3850402	2e-35	34.69897000433602	(Plasma kallikrein)	0.5188	[0.44-0.6] unit increase	Affymetrix [509946]	N	plasma kallikrein measurement	http://www.ebi.ac.uk/efo/EFO_0008260	GCST004365	Genome-wide genotyping array	0.3850402	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	9q34.2	9	133273813	ABO	ABO, ABO	NA	NA	ENSG00000175164, ENSG00000281879	NA	NA	rs505922-C	rs505922	0	505922	intron_variant	FALSE	0.3544177	8e-86	85.09691001300806	(CD209 antigen)	0.8177	[0.74-0.89] unit increase	Affymetrix [509946]	N	CD209 antigen measurement	http://www.ebi.ac.uk/efo/EFO_0008077	GCST004365	Genome-wide genotyping array	0.3544177	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	13q34	13	113185433	PROZ, PCID2, CUL4A	PCID2	NA	NA	ENSG00000126226	NA	NA	rs515863-T	rs515863	0	515863	intron_variant	FALSE	0.1696787	3e-26	25.522878745280337	(Dual specificity mitogen-activated protein kinase kinase 2)	0.5917	[0.49-0.7] unit decrease	Affymetrix [509946]	N	dual specificity mitogen-activated protein kinase kinase 2 measurement	http://www.ebi.ac.uk/efo/EFO_0008112	GCST004365	Genome-wide genotyping array	0.1696787	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	7q21.11	7	83638667	SEMA3E	SEMA3E	NA	NA	ENSG00000170381	NA	NA	rs536299-A	rs536299	0	536299	intron_variant	FALSE	0.3326633	2e-26	25.69897000433602	(Semaphorin-3E)	0.4734	[0.39-0.56] unit increase	Affymetrix [509946]	N	semaphorin-3E measurement	http://www.ebi.ac.uk/efo/EFO_0008279	GCST004365	Genome-wide genotyping array	0.3326633	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19p13.2	19	10285007	ICAM4, ICAM5, ICAM1, CTD-2369P2.5, CTD-2369P2.8	ICAM1	NA	NA	ENSG00000090339	NA	NA	rs5498-G	rs5498	0	5498	missense_variant	FALSE	0.4322969	8e-267	266.0969100130081	(Intercellular adhesion molecule 1)	1.217	[1.17-1.27] unit decrease	Affymetrix [509946]	N	ICAM-1 measurement	http://www.ebi.ac.uk/efo/EFO_0004520	GCST004365	Genome-wide genotyping array	0.4322969	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19p13.2	19	10285007	ICAM4, ICAM5, ICAM1, CTD-2369P2.5, CTD-2369P2.8	ICAM1	NA	NA	ENSG00000090339	NA	NA	rs5498-G	rs5498	0	5498	missense_variant	FALSE	0.4322969	2e-32	31.69897000433602	(Intercellular adhesion molecule 5)	0.5107	[0.43-0.59] unit increase	Affymetrix [509946]	N	intercellular adhesion molecule 5 measurement	http://www.ebi.ac.uk/efo/EFO_0008164	GCST004365	Genome-wide genotyping array	0.4322969	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6p21.33	6	31952910	SKIV2L, CFB, NELFE, C2, C2-AS1, XXbac-BPG116M5.17, MIR1236	NELFE, NELFE, NELFE, NELFE, NELFE, NELFE	NA	NA	ENSG00000204356, ENSG00000233801, ENSG00000206357, ENSG00000206268, ENSG00000229363, ENSG00000231044	NA	NA	rs550513-T	rs550513	0	550513	intron_variant	FALSE	0.07981928	1e-19	19	(Complement factor B)	0.702	[0.55-0.85] unit increase	Affymetrix [509946]	N	complement factor B measurement	http://www.ebi.ac.uk/efo/EFO_0008096	GCST004365	Genome-wide genotyping array	0.07981928	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6q25.3	6	160098244	RP11-288H12.3, IGF2R	IGF2R	NA	NA	ENSG00000197081	NA	NA	rs600324-T	rs600324	0	600324	intron_variant	FALSE	0.102719	7e-48	47.15490195998574	(Cation-independent mannose-6-phosphate receptor)	0.9818	[0.86-1.11] unit decrease	Affymetrix [509946]	N	cation-independent mannose-6-phosphate receptor measurement	http://www.ebi.ac.uk/efo/EFO_0008075	GCST004365	Genome-wide genotyping array	0.102719	NA	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition	4,097 European ancestry individuals	NA	3p12.3	3	78502757	ROBO1	NA - MRPS17P3	NA	ENSG00000239226	NA	NA	22344	rs17016200-G	rs17016200	0	17016200	intergenic_variant	TRUE	0.855	2e-6	5.698970004336019	NA	4.79	z score increase	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004727	Genome-wide genotyping array	0.855	4.79	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition	4,097 European ancestry individuals	NA	7p14.3	7	29651822	CHN2, PRR15, WIPF3	DPY19L2P3, ZNRF2P2	NA	NA	ENSG00000227855, ENSG00000225264	NA	NA	rs17604090-A	rs17604090	0	17604090	intron_variant	FALSE	0.151	3e-6	5.522878745280337	NA	4.71	z score increase	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004727	Genome-wide genotyping array	0.151	4.71	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition	4,097 European ancestry individuals	NA	5p15.2	5	11375862	CTNND2	CTNND2	NA	NA	ENSG00000169862	NA	NA	rs1423494-C	rs1423494	0	1423494	intron_variant	FALSE	0.415	4e-6	5.3979400086720375	NA	4.69	z score decrease	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004727	Genome-wide genotyping array	0.415	4.69	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (happy faces)	4,097 European ancestry individuals	NA	13q12.11	13	20150433	ZMYM2, GJA3, GJB2, GJB6	GJA3	NA	NA	ENSG00000121743	NA	NA	rs9550616-A	rs9550616	0	9550616	intron_variant	FALSE	0.355	3e-6	5.522878745280337	NA	4.69	z score decrease	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004729	Genome-wide genotyping array	0.355	4.69	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (sad faces)	4,097 European ancestry individuals	NA	2p11.2	2	86053802	POLR1A, PTCD3, SNORD94, IMMT, MRPL35, REEP1	POLR1A	NA	NA	ENSG00000068654	NA	NA	rs3770081-G	rs3770081	0	3770081	intron_variant	FALSE	0.9622	2e-6	5.698970004336019	NA	4.77	z score decrease	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004730	Genome-wide genotyping array	0.9622	4.77	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (sad faces)	4,097 European ancestry individuals	NA	7q22.1	7	99212934	SMURF1, KPNA7, MYH16, ARPC1A, ARPC1B, ARC41, PDAP1, BUD31, PTCD1, CPSF4, ATP5J2, ZNF789, ZNF394, ZKSCAN5, KIAA1015, C7orf38	KPNA7, KPNA7	NA	NA	ENSG00000284068, ENSG00000185467	NA	NA	rs12705054-A	rs12705054	0	12705054	intron_variant	FALSE	0.9364	3e-6	5.522878745280337	NA	4.65	z score decrease	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004730	Genome-wide genotyping array	0.9364	4.65	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (sad faces)	4,097 European ancestry individuals	NA	7p14.3	7	29651822	CHN2, PRR15, WIPF3	DPY19L2P3, ZNRF2P2	NA	NA	ENSG00000227855, ENSG00000225264	NA	NA	rs17604090-A	rs17604090	0	17604090	intron_variant	FALSE	0.151	4e-6	5.3979400086720375	NA	4.6	z score increase	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004730	Genome-wide genotyping array	0.151	4.6	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (sad faces)	4,097 European ancestry individuals	NA	13q21.33	13	72298068	intergenic	NA	NA	NA	NA	NA	NA	rs1146849-A	rs1146849	0	1146849	regulatory_region_variant	TRUE	0.278	4e-6	5.3979400086720375	NA	4.6	z score decrease	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004730	Genome-wide genotyping array	0.278	4.6	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (angry faces)	4,097 European ancestry individuals	NA	7p14.3	7	29657637	CHN2, PRR15, WIPF3	DPY19L2P3, ZNRF2P2	NA	NA	ENSG00000227855, ENSG00000225264	NA	NA	rs10248839-C	rs10248839	0	10248839	intron_variant	FALSE	0.16	4e-6	5.3979400086720375	NA	4.61	z score increase	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004728	Genome-wide genotyping array	0.16	4.61	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (angry faces)	4,097 European ancestry individuals	NA	7p21.3	7	11875617	THSD7A	THSD7A - NA	ENSG00000005108	NA	NA	43419	NA	rs10499395-G	rs10499395	0	10499395	intergenic_variant	TRUE	0.068	2e-6	5.698970004336019	NA	4.76	z score increase	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004728	Genome-wide genotyping array	0.068	4.76	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (angry faces)	4,097 European ancestry individuals	NA	12p11.22	12	28945324	intergenic	NA	NA	NA	NA	NA	NA	rs4930838-A	rs4930838	0	4930838	intergenic_variant	TRUE	0.156	3e-6	5.522878745280337	NA	4.65	z score increase	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004728	Genome-wide genotyping array	0.156	4.65	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (angry faces)	4,097 European ancestry individuals	NA	6q24.1	6	140771057	intergenic	RPS3AP24 - NA	ENSG00000217684	NA	NA	8795	NA	rs683257-A	rs683257	0	683257	intron_variant	TRUE	0.909	5e-6	5.301029995663981	NA	4.58	z score decrease	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004728	Genome-wide genotyping array	0.909	4.58	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (fearful faces)	4,097 European ancestry individuals	NA	6q22.1	6	117244581	VGLL2, ROS1, GOPC	NA - VGLL2	NA	ENSG00000170162	NA	NA	20977	rs654861-A	rs654861	0	654861	intergenic_variant	TRUE	0.968	1e-6	6	NA	4.86	z score increase	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004731	Genome-wide genotyping array	0.968	4.86	NA
2017-09-15	28608620	Coleman JRI	2017-06-13	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/28608620	Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders.	Facial emotion recognition (fearful faces)	4,097 European ancestry individuals	NA	3p12.3	3	78746928	ROBO1	ROBO1	NA	NA	ENSG00000169855	NA	NA	rs2304503-A	rs2304503	0	2304503	intron_variant	FALSE	0.522	4e-6	5.3979400086720375	NA	4.64	z score decrease	Illumina [2487351] (imputed)	N	facial emotion recognition measurement	http://www.ebi.ac.uk/efo/EFO_0008329	GCST004731	Genome-wide genotyping array	0.522	4.64	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	17q24.3	17	70457204	KCNJ2	NA	NA	NA	NA	NA	NA	rs8066985-A	rs8066985	0	8066985	intergenic_variant	TRUE	0.4857	6e-10	9.221848749616356	(women)	0.0281	[0.019-0.037] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.4857	NA	0.0281
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q13.3	15	31416060	KLF13	KLF13, KLF13	NA	NA	ENSG00000275746, ENSG00000169926	NA	NA	rs8042543-T	rs8042543	0	8042543	intron_variant	FALSE	0.2071	1e-7	7	(women)	0.0313	[0.02-0.043] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.2071	NA	0.0313
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q13.3	15	31416060	KLF13	KLF13, KLF13	NA	NA	ENSG00000275746, ENSG00000169926	NA	NA	rs8042543-T	rs8042543	0	8042543	intron_variant	FALSE	0.2071	2e-9	8.698970004336019	NA	0.0272	[0.018-0.036] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.2071	NA	0.0272
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q25.31	3	157079820	LEKR1	LEKR1 - LINC00880	ENSG00000197980	ENSG00000243629	NA	33691	1847	rs17451107-T	rs17451107	0	17451107	regulatory_region_variant	TRUE	0.6131	2e-9	8.698970004336019	NA	0.0214	[0.014-0.028] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.6131	NA	0.0214
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q25.31	3	157079820	LEKR1	LEKR1 - LINC00880	ENSG00000197980	ENSG00000243629	NA	33691	1847	rs17451107-T	rs17451107	0	17451107	regulatory_region_variant	TRUE	0.6131	4e-7	6.3979400086720375	(women)	0.0238	[0.015-0.033] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.6131	NA	0.0238
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p25.1	6	6738519	LY86	LY86 - BTF3P7	ENSG00000112799	ENSG00000219986	NA	83536	56396	rs1294410-T	rs1294410	0	1294410	intron_variant	TRUE	0.3725	7e-11	10.154901959985743	(women)	0.0306	[0.021-0.04] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.3725	NA	0.0306
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p25.1	6	6738519	LY86	LY86 - BTF3P7	ENSG00000112799	ENSG00000219986	NA	83536	56396	rs1294410-T	rs1294410	0	1294410	intron_variant	TRUE	0.3725	1e-12	12	NA	0.0256	[0.019-0.033] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.3725	NA	0.0256
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q41	1	219495884	LYPLA1	LYPLAL1-AS1 - NA	ENSG00000228536	NA	NA	36515	NA	rs765751-C	rs765751	0	765751	intergenic_variant	TRUE	0.611	9e-31	30.045757490560675	NA	0.031	[0.025-0.037] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.611	NA	0.031
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q41	1	219580167	LYPLAL1	NA - ZC3H11B	NA	ENSG00000215817	NA	NA	27843	rs2820443-T	rs2820443	0	2820443	regulatory_region_variant	TRUE	0.7255	4e-16	15.397940008672037	NA	0.0314	[0.024-0.039] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.7255	NA	0.0314
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q41	1	219580167	LYPLAL1	NA - ZC3H11B	NA	ENSG00000215817	NA	NA	27843	rs2820443-T	rs2820443	0	2820443	regulatory_region_variant	TRUE	0.7255	7e-28	27.154901959985743	(women)	0.0565	[0.046-0.067] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.7255	NA	0.0565
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	11q13.1	11	64095140	MACROD1, VEGFB	MACROD1, FLRT1	NA	NA	ENSG00000133315, ENSG00000126500	NA	NA	rs11231693-A	rs11231693	0	11231693	intron_variant	FALSE	0.0973	3e-6	5.522878745280337	NA	0.0336	[0.019-0.048] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.0973	NA	0.0336
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	11q13.1	11	64095140	MACROD1, VEGFB	MACROD1, FLRT1	NA	NA	ENSG00000133315, ENSG00000126500	NA	NA	rs11231693-A	rs11231693	0	11231693	intron_variant	FALSE	0.0973	1e-6	6	(women)	0.0447	[0.027-0.063] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.0973	NA	0.0447
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q11.2	5	56566067	MAP3K1	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs9687846-A	rs9687846	0	9687846	intron_variant	FALSE	0.1927	8e-6	5.096910013008056	(women)	0.026	[0.015-0.037] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.1927	NA	0.026
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q11.2	5	56565039	MAP3K1	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs3936510-T	rs3936510	0	3936510	intron_variant	FALSE	0.1898	8e-6	5.096910013008056	(women)	0.0263	[0.015-0.038] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.1898	NA	0.0263
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q11.2	5	56507706	MAP3K1	RPL26P19 - C5orf67	ENSG00000226221	ENSG00000225940	NA	2634	3861	rs30000-G	rs30000	0	30000	regulatory_region_variant	TRUE	0.26	3e-17	16.522878745280337	(EA, men)	0.039	[0.029-0.049] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.26	NA	0.039
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q11.2	5	56510924	MAP3K1	RPL26P19 - C5orf67	ENSG00000226221	ENSG00000225940	NA	5852	643	rs459193-A	rs459193	0	459193	intergenic_variant	TRUE	0.264	4e-20	19.397940008672037	(AA, men)	0.041	[0.033-0.049] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.264	NA	0.041
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2p14	2	65973514	MEIS1	NA	NA	NA	NA	NA	NA	rs1385167-A	rs1385167	0	1385167	intron_variant	TRUE	0.8459	3e-7	6.522878745280337	NA	0.0257	[0.016-0.035] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.8459	NA	0.0257
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8q13.3	8	71601993	MSC	EYA1 - NA	ENSG00000104313	NA	NA	9968	NA	rs12679556-T	rs12679556	0	12679556	intergenic_variant	TRUE	0.7074	2e-6	5.698970004336019	(women)	0.0246	[0.014-0.035] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.7074	NA	0.0246
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8q13.3	8	71601993	MSC	EYA1 - NA	ENSG00000104313	NA	NA	9968	NA	rs12679556-T	rs12679556	0	12679556	intergenic_variant	TRUE	0.7074	1e-9	9	NA	0.0241	[0.016-0.032] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.7074	NA	0.0241
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7p15.2	7	25822019	NFE2L3	NA	NA	NA	NA	NA	NA	rs3902751-A	rs3902751	0	3902751	intergenic_variant	TRUE	0.3178	1e-10	10	(women)	0.033	[0.023-0.043] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.3178	NA	0.033
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7p15.2	7	25818994	NFE2L3	NA	NA	NA	NA	NA	NA	rs10245353-A	rs10245353	0	10245353	intergenic_variant	TRUE	0.2306	4e-10	9.397940008672037	(women)	0.0371	[0.026-0.049] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.2306	NA	0.0371
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8p21.2	8	23745811	NKX2-6	NKX2-6 - STC1	ENSG00000180053	ENSG00000159167	NA	39055	96118	rs7830933-A	rs7830933	0	7830933	intron_variant	TRUE	0.7569	1e-11	11	(women)	0.0357	[0.025-0.046] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.7569	NA	0.0357
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p21.1	3	52532998	NT5DC2	NT5DC2	NA	NA	ENSG00000168268	NA	NA	rs12489828-T	rs12489828	0	12489828	intron_variant	FALSE	0.54	2e-6	5.698970004336019	NA	0.0173	[0.01-0.024] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.54	NA	0.0173
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p21.1	3	52603470	PBRM1	PBRM1	NA	NA	ENSG00000163939	NA	NA	rs2276824-C	rs2276824	0	2276824	intron_variant	FALSE	0.4352	2e-7	6.698970004336019	NA	0.0193	[0.012-0.027] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.4352	NA	0.0193
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p21.1	3	52603470	PBRM1	PBRM1	NA	NA	ENSG00000163939	NA	NA	rs2276824-C	rs2276824	0	2276824	intron_variant	FALSE	0.4352	9e-6	5.045757490560675	(women)	0.0215	[0.012-0.031] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.4352	NA	0.0215
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	17p11.2	17	17516885	PEMT	PEMT	NA	NA	ENSG00000133027	NA	NA	rs4646404-A	rs4646404	0	4646404	intron_variant	FALSE	0.3318	9e-6	5.045757490560675	NA	0.0181	[0.01-0.026] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.3318	NA	0.0181
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q22.1	3	129615390	PLXND1	PLXND1 - TMCC1	ENSG00000004399	ENSG00000172765	NA	8714	32402	rs10804591-A	rs10804591	0	10804591	intergenic_variant	TRUE	0.7415	3e-8	7.522878745280337	(women)	0.0339	[0.022-0.046] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.7415	NA	0.0339
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p25.2	3	12447843	PPARG	PPARG - TSEN2	ENSG00000132170	ENSG00000154743	NA	13487	36578	rs17819328-T	rs17819328	0	17819328	intergenic_variant	TRUE	0.5694	9e-10	9.045757490560675	(women)	0.0294	[0.02-0.039] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.5694	NA	0.0294
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p25.2	3	12447843	PPARG	PPARG - TSEN2	ENSG00000132170	ENSG00000154743	NA	13487	36578	rs17819328-T	rs17819328	0	17819328	intergenic_variant	TRUE	0.5694	6e-7	6.221848749616356	NA	0.0181	[0.011-0.025] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.5694	NA	0.0181
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p21.1	3	52615732	PRBM1	PBRM1	NA	NA	ENSG00000163939	NA	NA	rs13083798-A	rs13083798	0	13083798	intron_variant	FALSE	0.4986	1e-8	8	NA	0.0198	[0.013-0.027] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.4986	NA	0.0198
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p21.1	3	52615732	PRBM1	PBRM1	NA	NA	ENSG00000163939	NA	NA	rs13083798-A	rs13083798	0	13083798	intron_variant	FALSE	0.4986	7e-6	5.154901959985743	(women)	0.0204	[0.012-0.029] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.4986	NA	0.0204
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q22.33	6	127130971	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs1936805-T	rs1936805	0	1936805	intron_variant	FALSE	0.518	5e-7	6.301029995663981	(men)	0.026	[0.016-0.036] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.518	NA	0.026
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q22.33	6	127130971	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs1936805-T	rs1936805	0	1936805	intron_variant	FALSE	0.518	4e-23	22.397940008672037	NA	0.0345	[0.028-0.041] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.518	NA	0.0345
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q22.33	6	127133993	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs7766106-T	rs7766106	0	7766106	intron_variant	FALSE	0.486	4e-51	50.39794000867204	NA	0.039	[0.033-0.045] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.486	NA	0.039
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q22.33	6	127130971	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs1936805-T	rs1936805	0	1936805	intron_variant	FALSE	0.518	6e-20	19.221848749616356	(women)	0.0415	[0.033-0.05] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.518	NA	0.0415
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	10q24.32	10	102727686	SFXN2	SFXN2	NA	NA	ENSG00000156398	NA	NA	rs7917772-A	rs7917772	0	7917772	3_prime_UTR_variant	FALSE	0.6136	7e-6	5.154901959985743	NA	0.0161	[0.009-0.0232] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.6136	NA	0.0161
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	10q24.32	10	102727686	SFXN2	SFXN2	NA	NA	ENSG00000156398	NA	NA	rs7917772-A	rs7917772	0	7917772	3_prime_UTR_variant	FALSE	0.6136	5e-8	7.301029995663981	(women)	0.0253	[0.016-0.034] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.6136	NA	0.0253
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q22.31	15	66740813	SMAD6	SMAD6	NA	NA	ENSG00000137834	NA	NA	rs1440372-T	rs1440372	0	1440372	non_coding_transcript_exon_variant	FALSE	0.2874	7e-6	5.154901959985743	NA	0.0177	[0.01-0.025] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.2874	NA	0.0177
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	13q14.11	13	44053652	SMIM2	NRAD1 - LINC00390	ENSG00000233725	ENSG00000226519	NA	23191	41170	rs17065323-T	rs17065323	0	17065323	regulatory_region_variant	TRUE	0.006	1e-8	8	(EA)	0.139	[0.092-0.186] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.006	NA	0.139
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7p15.2	7	26357619	SNX10	SNX10	NA	NA	ENSG00000086300	NA	NA	rs1534696-A	rs1534696	0	1534696	intron_variant	FALSE	0.5684	1e-10	10	(women)	0.032	[0.022-0.042] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.5684	NA	0.032
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7p15.2	7	26357619	SNX10	SNX10	NA	NA	ENSG00000086300	NA	NA	rs1534696-A	rs1534696	0	1534696	intron_variant	FALSE	0.5684	3e-6	5.522878745280337	NA	0.0175	[0.01-0.025] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.5684	NA	0.0175
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118310352	SPAG17	RNA5SP56 - NA	ENSG00000222209	NA	NA	45863	NA	rs12731372-T	rs12731372	0	12731372	regulatory_region_variant	TRUE	0.2363	8e-7	6.096910013008056	NA	0.0204	[0.012-0.028] unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.2363	NA	0.0204
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	4q28.1	4	123145793	SPATA5, FGF2	SPATA5	NA	NA	ENSG00000145375	NA	NA	rs303084-A	rs303084	0	303084	intron_variant	FALSE	0.748	8e-6	5.096910013008056	NA	0.02	[0.011-0.029] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.748	NA	0.02
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118954531	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs12143789-C	rs12143789	0	12143789	intron_variant	FALSE	0.1892	2e-7	6.698970004336019	NA	0.0235	[0.015-0.032] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.1892	NA	0.0235
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118988874	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs1106529-A	rs1106529	0	1106529	intron_variant	FALSE	0.7439	5e-8	7.301029995663981	(men)	0.0323	[0.021-0.044] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.7439	NA	0.0323
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118988874	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs1106529-A	rs1106529	0	1106529	intron_variant	FALSE	0.7439	3e-17	16.522878745280337	NA	0.0334	[0.026-0.041] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.7439	NA	0.0334
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	118988874	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs1106529-A	rs1106529	0	1106529	intron_variant	FALSE	0.7439	2e-11	10.698970004336019	(women)	0.0346	[0.024-0.045] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.7439	NA	0.0346
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	119031964	TBX15, WARS2	WARS2	NA	NA	ENSG00000116874	NA	NA	rs2645294-T	rs2645294	0	2645294	3_prime_UTR_variant	FALSE	0.5659	7e-10	9.154901959985743	(men)	0.0323	[0.022-0.042] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.5659	NA	0.0323
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	119031964	TBX15, WARS2	WARS2	NA	NA	ENSG00000116874	NA	NA	rs2645294-T	rs2645294	0	2645294	3_prime_UTR_variant	FALSE	0.5659	1e-21	21	NA	0.0331	[0.026-0.04] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.5659	NA	0.0331
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)	95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p12	1	119031964	TBX15, WARS2	WARS2	NA	NA	ENSG00000116874	NA	NA	rs2645294-T	rs2645294	0	2645294	3_prime_UTR_variant	FALSE	0.5659	6e-14	13.221848749616356	(women)	0.0341	[0.025-0.043] unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788	GCST004505	Genome-wide genotyping array	0.5659	NA	0.0341
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	11p15.1	11	17343662	NUCB2	NUCB2	NA	NA	ENSG00000070081	NA	NA	rs2051773-?	rs2051773	0	2051773	intron_variant	FALSE	0.2911	2e-7	6.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2911	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12p12.1	12	26290097	ITPR2, SSPN	SSPN	NA	NA	ENSG00000123096	NA	NA	rs4963975-?	rs4963975	0	4963975	intron_variant	FALSE	0.2535	2e-8	7.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2535	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12p11.22	12	28318386	CCDC91	CCDC91	NA	NA	ENSG00000123106	NA	NA	rs10843151-?	rs10843151	0	10843151	intron_variant	FALSE	0.6900999999999999	2e-9	8.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6900999999999999	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q13.13	12	54027692	HOXC4, HOXC5, HOXC6	HOXC4, HOXC6	NA	NA	ENSG00000198353, ENSG00000197757	NA	NA	rs10876528-?	rs10876528	0	10876528	intron_variant	FALSE	0.3539	3e-12	11.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3539	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q24.31	12	123920171	DNAH10	CCDC92, DNAH10	NA	NA	ENSG00000119242, ENSG00000197653	NA	NA	rs12317176-?	rs12317176	0	12317176	intron_variant	FALSE	0.65	1e-11	11	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.65	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q23	15	70072013	TLE3	TLE3	NA	NA	ENSG00000140332	NA	NA	rs975210-?	rs975210	0	975210	intron_variant	FALSE	0.1811	4e-7	6.3979400086720375	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.1811	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q24.1	15	73936469	LOXL1	LOXL1	NA	NA	ENSG00000129038	NA	NA	rs4886782-?	rs4886782	0	4886782	intron_variant	FALSE	0.6305000000000001	3e-10	9.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6305000000000001	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	83913372	ADAMTSL3	ADAMTSL3	NA	NA	ENSG00000156218	NA	NA	rs4842838-?	rs4842838	0	4842838	missense_variant	FALSE	0.5348	7e-26	25.154901959985743	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5348	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	84597563	ZSCAN2	LINC00933 - ZSCAN2	ENSG00000259728	ENSG00000176371	NA	17388	3423	rs7176527-?	rs7176527	0	7176527	intergenic_variant	TRUE	0.8083	1e-7	7	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.8083	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q26.1	15	88872016	ACAN	ACAN	NA	NA	ENSG00000157766	NA	NA	rs3817428-?	rs3817428	0	3817428	missense_variant	FALSE	0.7327	3e-8	7.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7327	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	16q22.1	16	67346647	LRRC36	LRRC36	NA	NA	ENSG00000159708	NA	NA	rs7184253-?	rs7184253	0	7184253	intron_variant	FALSE	0.8755	2e-8	7.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.8755	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17p13.3	17	560603	VPS53	VPS53, VPS53	NA	NA	ENSG00000141252, ENSG00000283883	NA	NA	rs741677-?	rs741677	0	741677	intron_variant	FALSE	0.5689	7e-9	8.154901959985743	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5689	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q23.2	17	61419916	C17orf82	LINC02875 - TBX4	ENSG00000187013	ENSG00000121075	NA	6636	32488	rs757608-?	rs757608	0	757608	regulatory_region_variant	TRUE	0.3157	1e-11	11	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3157	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	18q11.2	18	23151966	CABLES1	CABLES1	NA	NA	ENSG00000134508	NA	NA	rs4239436-?	rs4239436	0	4239436	intron_variant	FALSE	0.794	1e-18	18	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.794	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	19p13.2	19	8577276	MYO1F	MYO1F	NA	NA	ENSG00000142347	NA	NA	rs4542783-?	rs4542783	0	4542783	non_coding_transcript_exon_variant	FALSE	0.5413	1e-7	7	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5413	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	19q13.11	19	33402102	PEPD	PEPD	NA	NA	ENSG00000124299	NA	NA	rs3786897-?	rs3786897	0	3786897	intron_variant	FALSE	0.42379999999999995	5e-9	8.301029995663981	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.42379999999999995	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	20p12.3	20	6632185	LOC149844, BMP2	NA - LINC01713	NA	ENSG00000228482	NA	NA	98895	rs1884897-?	rs1884897	0	1884897	regulatory_region_variant	TRUE	0.3681	1e-8	8	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3681	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p36.13	1	16981663	MFAP2	MFAP2 - ATP13A2	ENSG00000117122	ENSG00000159363	NA	1031	4295	rs9435732-?	rs9435732	0	9435732	intron_variant	TRUE	0.7313000000000001	2e-10	9.698970004336019	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7313000000000001	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118307286	SPAG17	RNA5SP56 - NA	ENSG00000222209	NA	NA	42797	NA	rs7513580-?	rs7513580	0	7513580	intergenic_variant	TRUE	0.6957	7e-11	10.154901959985743	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6957	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118962811	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs10923712-?	rs10923712	0	10923712	intron_variant	FALSE	0.6229	8e-13	12.096910013008056	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6229	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q21.2	1	149934520	MTMR11	MTMR11	NA	NA	ENSG00000014914	NA	NA	rs11205303-?	rs11205303	0	11205303	missense_variant	FALSE	0.3839	2e-6	5.698970004336019	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3839	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.3	1	184051811	TSEN15	TSEN15	NA	NA	ENSG00000198860	NA	NA	rs2274432-?	rs2274432	0	2274432	missense_variant	FALSE	0.3569	3e-6	5.522878745280337	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3569	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q41	1	218436360	TGFB2, LYPLAL1	TGFB2	NA	NA	ENSG00000092969	NA	NA	rs6684205-?	rs6684205	0	6684205	intron_variant	FALSE	0.2882	3e-11	10.522878745280337	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2882	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p23.3	2	25263901	DNMT3A	DNMT3A	NA	NA	ENSG00000119772	NA	NA	rs12991495-?	rs12991495	0	12991495	intron_variant	FALSE	0.692	2e-6	5.698970004336019	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.692	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p22.3	2	33154196	LTBP1	LTBP1	NA	NA	ENSG00000049323	NA	NA	rs6715793-?	rs6715793	0	6715793	intron_variant	FALSE	0.5104	2e-6	5.698970004336019	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5104	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p16.1	2	55869757	EFEMP1	EFEMP1	NA	NA	ENSG00000115380	NA	NA	rs3791679-?	rs3791679	0	3791679	intron_variant	FALSE	0.7605	2e-14	13.698970004336019	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7605	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2q37.1	2	231995367	DIS3L2	DIS3L2	NA	NA	ENSG00000144535	NA	NA	rs3116162-?	rs3116162	0	3116162	intron_variant	FALSE	0.9133	1e-6	6	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.9133	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2q37.1	2	232320342	DIS3L2	DIS3L2	NA	NA	ENSG00000144535	NA	NA	rs6437061-?	rs6437061	0	6437061	intron_variant	FALSE	0.5973	1e-9	9	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5973	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p13	3	72406204	RYBP	RYBP, RYBP	NA	NA	ENSG00000163602, ENSG00000281766	NA	NA	rs12330322-?	rs12330322	0	12330322	intron_variant	FALSE	0.7823	4e-7	6.3979400086720375	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7823	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q23	3	141406863	ZBTB38	ZBTB38	NA	NA	ENSG00000177311	NA	NA	rs1344672-?	rs1344672	0	1344672	intron_variant	FALSE	0.43720000000000003	5e-12	11.301029995663981	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.43720000000000003	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q26.31	3	172204265	FNDC3B	FNDC3B	NA	NA	ENSG00000075420	NA	NA	rs12493901-?	rs12493901	0	12493901	intron_variant	FALSE	0.512	1e-7	7	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.512	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4q31.21	4	144653692	HHIP	HHIP-AS1, HHIP	NA	NA	ENSG00000248890, ENSG00000164161	NA	NA	rs1812175-?	rs1812175	0	1812175	intron_variant	FALSE	0.8336	9e-11	10.045757490560675	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.8336	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q35.3	5	177100576	FGFR4	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-?	rs6556301	0	6556301	intergenic_variant	TRUE	0.3576	3e-9	8.522878745280337	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3576	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q35.3	5	177299634	NSD1	NSD1	NA	NA	ENSG00000165671	NA	NA	rs3088050-?	rs3088050	0	3088050	3_prime_UTR_variant	FALSE	0.2143	1e-10	10	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2143	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p22.2	6	26200449	HIST1H2BF	H2BC7	NA	NA	ENSG00000277224	NA	NA	rs806794-?	rs806794	0	806794	3_prime_UTR_variant	FALSE	0.6986	5e-8	7.301029995663981	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6986	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q14.1	6	75529546	FILIP1	RPL26P20 - H3P27	ENSG00000219722	ENSG00000220730	NA	29410	56576	rs13192994-?	rs13192994	0	13192994	intergenic_variant	TRUE	0.14490000000000003	6e-6	5.221848749616356	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.14490000000000003	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q16.3	6	104931079	LIN28B	LIN28B-AS1	NA	NA	ENSG00000203809	NA	NA	rs7759938-?	rs7759938	0	7759938	intron_variant	FALSE	0.32089999999999996	1e-13	13	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.32089999999999996	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q24.2	6	142382740	GPR126	ADGRG6	NA	NA	ENSG00000112414	NA	NA	rs4896582-?	rs4896582	0	4896582	intron_variant	FALSE	0.6960999999999999	1e-8	8	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6960999999999999	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p22.3	7	2762169	AMZ1	GNA12, AMZ1	NA	NA	ENSG00000146535, ENSG00000174945	NA	NA	rs798489-?	rs798489	0	798489	splice_donor_variant	FALSE	0.7105	2e-7	6.698970004336019	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7105	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	25831489	UBA52P1	NA	NA	NA	NA	NA	NA	rs1055144-?	rs1055144	0	1055144	non_coding_transcript_exon_variant	TRUE	0.1983	3e-6	5.522878745280337	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.1983	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.1	7	28167681	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs481806-?	rs481806	0	481806	intron_variant	FALSE	0.2964	1e-8	8	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2964	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9q22.32	9	95648123	PTCH1	NA	NA	NA	NA	NA	NA	rs10990303-?	rs10990303	0	10990303	intergenic_variant	TRUE	0.2238	9e-8	7.045757490560675	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2238	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9q31.2	9	106156346	TMEM38B	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs7032974-?	rs7032974	0	7032974	intron_variant	FALSE	0.7183	2e-8	7.698970004336019	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7183	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9q31.2	9	106876781	ZNF462	ZNF462	NA	NA	ENSG00000148143	NA	NA	rs7874161-?	rs7874161	0	7874161	intron_variant	FALSE	0.3504	7e-8	7.154901959985743	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3504	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q13.13	12	54027692	HOXC4, HOXC5, HOXC6	HOXC4, HOXC6	NA	NA	ENSG00000198353, ENSG00000197757	NA	NA	rs10876528-?	rs10876528	0	10876528	intron_variant	FALSE	0.3597	4e-8	7.3979400086720375	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3597	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q24.1	15	73936469	LOXL1	LOXL1	NA	NA	ENSG00000129038	NA	NA	rs4886782-?	rs4886782	0	4886782	intron_variant	FALSE	0.6194	2e-9	8.698970004336019	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6194	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	83915207	ADAMTSL3	ADAMTSL3	NA	NA	ENSG00000156218	NA	NA	rs2030839-?	rs2030839	0	2030839	intron_variant	FALSE	0.5211	1e-15	15	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5211	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	84597563	ZSCAN2	LINC00933 - ZSCAN2	ENSG00000259728	ENSG00000176371	NA	17388	3423	rs7176527-?	rs7176527	0	7176527	intergenic_variant	TRUE	0.8071	8e-6	5.096910013008056	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.8071	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q11.2	17	30837005	ATAD5	ATAD5	NA	NA	ENSG00000176208	NA	NA	rs3764419-?	rs3764419	0	3764419	intron_variant	FALSE	0.6093	2e-7	6.698970004336019	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6093	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q23.2	17	61419916	C17orf82	LINC02875 - TBX4	ENSG00000187013	ENSG00000121075	NA	6636	32488	rs757608-?	rs757608	0	757608	regulatory_region_variant	TRUE	0.3207	5e-6	5.301029995663981	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3207	NA	NA
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (cystatin C)	24,063 European ancestry individuals	NA	NA	NA	NA	CST3, CST9	NA	NA	NA	NA	NA	NA	CST3/CST9-?	CST3/CST9	0	NA	NA	TRUE	NR	4e-153	152.39794000867204	NA	NA	NA	Affymetrix, Illumina [up to 10971307] (imputed)	N	glomerular filtration rate, cystatin C measurement	http://www.ebi.ac.uk/efo/EFO_0005208, http://www.ebi.ac.uk/efo/EFO_0004617	GCST004293	Genome-wide genotyping array	NA	NA	NA
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (cystatin C)	24,063 European ancestry individuals	NA	NA	NA	NA	UMOD	NA	NA	NA	NA	NA	NA	UMOD-?	UMOD	0	NA	NA	TRUE	NR	3e-10	9.522878745280337	NA	NA	NA	Affymetrix, Illumina [up to 10971307] (imputed)	N	glomerular filtration rate, cystatin C measurement	http://www.ebi.ac.uk/efo/EFO_0005208, http://www.ebi.ac.uk/efo/EFO_0004617	GCST004293	Genome-wide genotyping array	NA	NA	NA
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (cystatin C)	24,063 European ancestry individuals	NA	NA	NA	NA	ATXN2	NA	NA	NA	NA	NA	NA	ATXN2-?	ATXN2	0	NA	NA	TRUE	NR	2e-8	7.698970004336019	NA	NA	NA	Affymetrix, Illumina [up to 10971307] (imputed)	N	glomerular filtration rate, cystatin C measurement	http://www.ebi.ac.uk/efo/EFO_0005208, http://www.ebi.ac.uk/efo/EFO_0004617	GCST004293	Genome-wide genotyping array	NA	NA	NA
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	1p36.21	1	15528628	CASP9	DNAJC16	NA	NA	ENSG00000116138	NA	NA	rs7546668-C	rs7546668	0	7546668	intron_variant	FALSE	NR	1e-9	9	NA	0.0063	[0.0043-0.0083] unit decrease	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0063
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	1p13.3	1	109348511	SYPL2	SORT1	NA	NA	ENSG00000134243	NA	NA	rs10127790-T	rs10127790	0	10127790	intron_variant	FALSE	NR	8e-9	8.096910013008056	NA	0.0061	[0.0041-0.0081] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0061
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	1q21.3	1	150968149	ANXA9	CERS2	NA	NA	ENSG00000143418	NA	NA	rs267738-T	rs267738	0	267738	missense_variant	FALSE	NR	1e-14	14	NA	0.0091	[0.0069-0.0113] unit decrease	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0091
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	1q32.1	1	201047168	CACNA1S	CACNA1S	NA	NA	ENSG00000081248	NA	NA	rs3850625-A	rs3850625	0	3850625	missense_variant	FALSE	NR	2e-8	7.698970004336019	NA	0.0088	[0.0059-0.0117] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0088
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	2p24.3	2	15652890	DDX1	DDX1 - LINC01804	ENSG00000079785	ENSG00000231031	NA	18544	37892	rs807601-T	rs807601	0	807601	intergenic_variant	TRUE	NR	4e-11	10.397940008672037	NA	0.0067	[0.0047-0.0087] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0067
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	2p23.3	2	27519736	GCKR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs780093-T	rs780093	0	780093	intron_variant	FALSE	NR	2e-16	15.698970004336019	NA	0.0081	[0.0063-0.0099] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0081
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	2p13.1	2	73540770	NAT8	ALMS1	NA	NA	ENSG00000116127	NA	NA	rs4500972-A	rs4500972	0	4500972	intron_variant	FALSE	NR	3e-18	17.522878745280337	NA	0.0108	[0.0084-0.0132] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0108
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	2q34	2	210675783	CPS1	CPS1	NA	NA	ENSG00000021826	NA	NA	rs1047891-A	rs1047891	0	1047891	missense_variant	FALSE	NR	2e-16	15.698970004336019	NA	0.0089	[0.0069-0.0109] unit decrease	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0089
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	3q23	3	142094330	TFDP2	TFDP2	NA	NA	ENSG00000114126	NA	NA	rs7640665-A	rs7640665	0	7640665	intron_variant	FALSE	NR	5e-11	10.301029995663981	NA	0.0072	[0.0052-0.0092] unit decrease	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0072
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	3q27.2	3	186096853	ETV5	ETV5	NA	NA	ENSG00000244405	NA	NA	rs6809651-A	rs6809651	0	6809651	intron_variant	FALSE	NR	2e-8	7.698970004336019	NA	0.0081	[0.0054-0.0108] unit decrease	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0081
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	4q21.1	4	76490987	SHROOM3	SHROOM3	NA	NA	ENSG00000138771	NA	NA	rs13146355-A	rs13146355	0	13146355	intron_variant	FALSE	NR	3e-37	36.52287874528034	NA	0.0121	[0.01-0.014] unit decrease	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0121
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	5p13.1	5	39367637	DAB2	C9	NA	NA	ENSG00000113600	NA	NA	rs700236-A	rs700236	0	700236	intron_variant	FALSE	NR	2e-18	17.69897000433602	NA	0.0084	[0.0066-0.0102] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0084
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	5q35.3	5	177386403	SLC34A1	SLC34A1	NA	NA	ENSG00000131183	NA	NA	rs3812036-T	rs3812036	0	3812036	intron_variant	FALSE	NR	9e-19	18.045757490560675	NA	0.0102	[0.008-0.0124] unit decrease	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0102
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	6p21.1	6	43838598	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	52111	6280	rs1317983-T	rs1317983	0	1317983	intron_variant	TRUE	NR	1e-13	13	NA	0.008	[0.006-0.01] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.008
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	6q25.3	6	160247357	SLC22A2	SLC22A2	NA	NA	ENSG00000112499	NA	NA	rs2279463-A	rs2279463	0	2279463	intron_variant	FALSE	NR	1e-15	15	NA	0.0118	[0.0091-0.0145] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0118
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	7p22.3	7	1246931	UNCX	UNCX - MICALL2	ENSG00000164853	ENSG00000164877	NA	9605	181534	rs62435145-T	rs62435145	0	62435145	regulatory_region_variant	TRUE	NR	3e-8	7.522878745280337	NA	0.0077	[0.0052-0.0102] unit decrease	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0077
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	7q11.23	7	77609361	TMEM60	PTPN12	NA	NA	ENSG00000127947	NA	NA	rs112029703-A	rs112029703	0	112029703	intron_variant	FALSE	NR	1e-9	9	NA	0.0065	[0.0045-0.0085] unit decrease	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0065
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	7q36.1	7	151718450	PRKAG2	PRKAG2	NA	NA	ENSG00000106617	NA	NA	rs10254101-T	rs10254101	0	10254101	intron_variant	FALSE	NR	6e-20	19.221848749616356	NA	0.0104	[0.0082-0.0126] unit decrease	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0104
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	8p21.2	8	23858358	STC1	STC1 - NA	ENSG00000159167	NA	NA	3552	NA	rs36071802-T	rs36071802	0	36071802	intergenic_variant	TRUE	NR	1e-15	15	NA	0.0079	[0.0061-0.0097] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0079
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	9q21.11	9	68819549	PIP5K1B	PIP5K1B	NA	NA	ENSG00000107242	NA	NA	rs10746942-A	rs10746942	0	10746942	intron_variant	FALSE	NR	4e-18	17.397940008672037	NA	0.0086	[0.0068-0.0104] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0086
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	10p15.3	10	853131	WDR37	LARP4B	NA	NA	ENSG00000107929	NA	NA	rs80282103-A	rs80282103	0	80282103	intron_variant	FALSE	NR	1e-11	11	NA	0.0123	[0.009-0.0156] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0123
2017-07-06	28452372	Gorski M	2017-04-28	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Glomerular filtration rate (creatinine)	110,517 European ancestry individuals	NA	10q11.23	10	50885488	A1CF	A1CF	NA	NA	ENSG00000148584	NA	NA	rs10994856-A	rs10994856	0	10994856	intron_variant	FALSE	NR	5e-9	8.301029995663981	NA	0.0075	[0.0051-0.0099] unit increase	Affymetrix, Illumina [up to 10971307] (imputed)	N	creatinine measurement, glomerular filtration rate	http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208	GCST004292	Genome-wide genotyping array	NA	NA	0.0075
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	16p13.3	16	4973060	SEC14L5	SEC14L5	NA	NA	ENSG00000103184	NA	NA	rs9925477-G	rs9925477	0	9925477	intron_variant	FALSE	0.4668	3e-19	18.522878745280337	NA	0.03309418	[0.026-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4668	NA	0.03309418
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	16p12.1	16	28495107	APOBR	CLN3, APOBR	NA	NA	ENSG00000188603, ENSG00000184730	NA	NA	rs151233-T	rs151233	0	151233	synonymous_variant	FALSE	0.1309	3e-37	36.52287874528034	NA	0.06854762	[0.058-0.079] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1309	NA	0.06854762
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	16p11.2	16	29855475	CDIPT	MVP - CDIPT	ENSG00000013364	ENSG00000103502	NA	7436	2882	rs528863805-AT	rs528863805	1	35566610	intergenic_variant	TRUE	0.1585	2e-9	8.698970004336019	NA	0.03061159	[0.021-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1585	NA	0.03061159
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	16q23.3	16	81837364	PLCG2	PLCG2	NA	NA	ENSG00000197943	NA	NA	rs12445050-T	rs12445050	0	12445050	intron_variant	FALSE	0.1369	3e-26	25.522878745280337	NA	0.05624268	[0.046-0.067] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1369	NA	0.05624268
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	16q24.3	16	88950086	CBFA2T3, RP11-830F9.6	CBFA2T3	NA	NA	ENSG00000129993	NA	NA	rs12102677-C	rs12102677	0	12102677	intron_variant	FALSE	0.372	5e-11	10.301029995663981	NA	0.02467971	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.372	NA	0.02467971
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17p13.3	17	1512616	INPP5K	INPP5K	NA	NA	ENSG00000132376	NA	NA	rs939563-A	rs939563	0	939563	intron_variant	FALSE	0.519	2e-9	8.698970004336019	NA	0.02163254	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.519	NA	0.02163254
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17p13.2	17	4933900	GP1BA	CHRNE, GP1BA	NA	NA	ENSG00000108556, ENSG00000185245	NA	NA	rs553749201-A	rs553749201	0	553749201	synonymous_variant	FALSE	0.0547	8e-10	9.096910013008056	NA	0.05033656	[0.034-0.066] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0547	NA	0.05033656
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17p13.2	17	4965849	SPAG7	SPAG7	NA	NA	ENSG00000091640	NA	NA	rs571461910-TTATC	rs571461910	0	571461910	non_coding_transcript_exon_variant	FALSE	0.0612	4e-9	8.397940008672037	NA	0.04505136	[0.03-0.06] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0612	NA	0.04505136
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17p11.2	17	17009366	RP11-416I2.1	LINC02090 - MPRIP	ENSG00000230969	ENSG00000133030	NA	19189	33091	rs7225537-G	rs7225537	0	7225537	intergenic_variant	TRUE	0.4661	4e-12	11.397940008672037	NA	0.02538979	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4661	NA	0.02538979
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17p11.2	17	19920960	AKAP10	AKAP10	NA	NA	ENSG00000108599	NA	NA	rs57112968-C	rs57112968	0	57112968	intron_variant	FALSE	0.397	5e-14	13.301029995663981	NA	0.02810363	[0.021-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.397	NA	0.02810363
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q11.2	17	29446271	TAOK1	TAOK1	NA	NA	ENSG00000160551	NA	NA	rs9891920-G	rs9891920	0	9891920	intron_variant	FALSE	0.5145	2e-298	297.69897000433605	NA	0.1333078	[0.13-0.14] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5145	NA	0.1333078
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q11.2	17	29451055	TAOK1	TAOK1	NA	NA	ENSG00000160551	NA	NA	rs191010498-T	rs191010498	0	191010498	intron_variant	FALSE	0.0107	2e-26	25.69897000433602	NA	0.1917807	[0.16-0.23] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0107	NA	0.1917807
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q11.2	17	29518760	TAOK1	TAOK1	NA	NA	ENSG00000160551	NA	NA	rs7209300-C	rs7209300	0	7209300	intron_variant	FALSE	0.1807	2e-139	138.69897000433602	NA	0.1185384	[0.11-0.13] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1807	NA	0.1185384
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q11.2	17	30830140	ATAD5, CTD-2349P21.1	CRLF3 - ATAD5	ENSG00000176390	ENSG00000176208	NA	5448	1826	rs74815160-T	rs74815160	0	74815160	intergenic_variant	TRUE	0.2146	3e-9	8.522878745280337	NA	0.02686886	[0.018-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2146	NA	0.02686886
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q12	17	35559745	SLFN14	SLFN14	NA	NA	ENSG00000236320	NA	NA	rs145171343-T	rs145171343	0	145171343	5_prime_UTR_variant	FALSE	0.0171	5e-10	9.301029995663981	NA	0.09053362	[0.062-0.119] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0171	NA	0.09053362
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q12	17	35632228	AP2B1	AP2B1	NA	NA	ENSG00000006125	NA	NA	rs11868206-A	rs11868206	0	11868206	intron_variant	FALSE	0.1782	5e-38	37.30102999566398	NA	0.06073825	[0.052-0.07] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1782	NA	0.06073825
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q12	17	35680792	CTC-507E2.1	AP2B1	NA	NA	ENSG00000006125	NA	NA	rs112346425-C	rs112346425	0	112346425	intron_variant	FALSE	0.0383	6e-31	30.221848749616356	NA	0.1097456	[0.091-0.128] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0383	NA	0.1097456
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q21.31	17	44377655	ITGA2B	ITGA2B	NA	NA	ENSG00000005961	NA	NA	rs34603233-T	rs34603233	1	25552	intron_variant	FALSE	0.3735	2e-37	36.69897000433602	NA	0.04765577	[0.04-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3735	NA	0.04765577
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q21.32	17	47252031	ITGB3	MYL4 - ITGB3	ENSG00000198336	ENSG00000259207	NA	28352	1796	rs117107187-G	rs117107187	0	117107187	intergenic_variant	TRUE	0.0087	2e-10	9.698970004336019	NA	0.1346571	[0.093-0.176] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0087	NA	0.1346571
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q21.32	17	47531904	NPEPPS	NPEPPS	NA	NA	ENSG00000141279	NA	NA	rs62073968-G	rs62073968	0	62073968	intron_variant	FALSE	0.214	3e-12	11.522878745280337	NA	0.03100656	[0.022-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.214	NA	0.03100656
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q22	17	57385980	MSI2	MSI2	NA	NA	ENSG00000153944	NA	NA	rs188761458-T	rs188761458	0	188761458	intron_variant	FALSE	0.0488	8e-14	13.096910013008056	NA	0.06372918	[0.047-0.08] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0488	NA	0.06372918
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	17q23.3	17	64307290	RPL31P57	TEX2 - RPL31P57	ENSG00000136478	ENSG00000256358	NA	44030	1026	rs11356207-C	rs11356207	0	11356207	regulatory_region_variant	TRUE	0.5494	1e-14	14	NA	0.02727351	[0.02-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5494	NA	0.02727351
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	18p11.22	18	9617722	RP11-692N5.1	PPP4R1-AS1	NA	NA	ENSG00000263627	NA	NA	rs11315757-T	rs11315757	0	11315757	intron_variant	FALSE	0.7418	5e-30	29.30102999566398	NA	0.04720458	[0.039-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.7418	NA	0.04720458
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	18q11.2	18	23141009	CABLES1	CABLES1	NA	NA	ENSG00000134508	NA	NA	rs11082304-T	rs11082304	0	11082304	intron_variant	FALSE	0.5125	2e-33	32.69897000433602	NA	0.0436094	[0.037-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5125	NA	0.0436094
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	18q12.3	18	44482415	CTC-782O7.1	LINC01478	NA	NA	ENSG00000267337	NA	NA	rs75763843-C	rs75763843	0	75763843	intron_variant	FALSE	0.1293	8e-14	13.096910013008056	NA	0.04017044	[0.03-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1293	NA	0.04017044
2017-12-01	28924203	Ren HY	2017-09-18	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28924203	The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia.	White matter microstructure in first episode schizophrenia (right posterior cingulate cortex)	93 Han Chinese cases, 134 Han Chinese controls	NA	NA	NA	NA	DLGAP2	NA	NA	NA	NA	NA	NA	kgp5929161-?	kgp5929161	0	NA	NA	TRUE	NR	6e-7	6.221848749616356	NA	0.06	unit increase	Illumina [6055918] (imputed)	N	white matter microstructure measurement, cingulate cortex measurement	http://www.ebi.ac.uk/efo/EFO_0005674, http://www.ebi.ac.uk/efo/EFO_0007738	GCST004992	Genome-wide genotyping array	NA	NA	0.06
2017-12-01	28924203	Ren HY	2017-09-18	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28924203	The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia.	Total mean fractional anisotropy measurement in first episode schizophrenia	93 Han Chinese cases, 134 Han Chinese controls	NA	2q37.3	2	236588594	CXCR7	ACKR3 - NA	ENSG00000144476	NA	NA	6240	NA	rs11901793-?	rs11901793	0	11901793	regulatory_region_variant	TRUE	NR	4e-8	7.3979400086720375	NA	0.02	unit decrease	Illumina [6055918] (imputed)	N	mean fractional anisotropy measurement, white matter microstructure measurement	http://www.ebi.ac.uk/efo/EFO_0008399, http://www.ebi.ac.uk/efo/EFO_0005674	GCST004996	Genome-wide genotyping array	NA	NA	0.02
2017-12-01	28924203	Ren HY	2017-09-18	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28924203	The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia.	White matter microstructure in first episode schizophrenia (left posterior cingulate cortex)	93 Han Chinese cases, 134 Han Chinese controls	NA	10q25.1	10	107815336	SORCS1	LINC01435	NA	NA	ENSG00000229981	NA	NA	rs10509852-?	rs10509852	0	10509852	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.04	unit decrease	Illumina [6055918] (imputed)	N	white matter microstructure measurement, cingulate cortex measurement	http://www.ebi.ac.uk/efo/EFO_0005674, http://www.ebi.ac.uk/efo/EFO_0007738	GCST004995	Genome-wide genotyping array	NA	NA	0.04
2017-12-01	28924203	Ren HY	2017-09-18	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28924203	The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia.	White matter microstructure in first episode schizophrenia (left inferior parietal cortex)	93 Han Chinese cases, 134 Han Chinese controls	NA	2q33.1	2	201666824	MPP4	MPP4	NA	NA	ENSG00000082126	NA	NA	rs7559992-?	rs7559992	0	7559992	intron_variant	FALSE	NR	9e-8	7.045757490560675	NA	0.03	unit decrease	Illumina [6055918] (imputed)	N	parietal cortex measurement, white matter microstructure measurement	http://www.ebi.ac.uk/efo/EFO_0008420, http://www.ebi.ac.uk/efo/EFO_0005674	GCST004991	Genome-wide genotyping array	NA	NA	0.03
2017-12-01	28924203	Ren HY	2017-09-18	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28924203	The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia.	Abnormal white matter microstructure in first episode schizophrenia (multivariate analysis)	93 Han Chinese cases, 134 Han Chinese controls	NA	10q25.1	10	107815336	SORCS1	LINC01435	NA	NA	ENSG00000229981	NA	NA	rs10509852-?	rs10509852	0	10509852	intron_variant	FALSE	NR	2e-7	6.698970004336019	NA	NA	NA	Illumina [6055918] (imputed)	N	parietal cortex measurement, white matter microstructure measurement, cingulate cortex measurement	http://www.ebi.ac.uk/efo/EFO_0008420, http://www.ebi.ac.uk/efo/EFO_0005674, http://www.ebi.ac.uk/efo/EFO_0007738	GCST004997	Genome-wide genotyping array	NA	NA	NA
2017-12-01	28924203	Ren HY	2017-09-18	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28924203	The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia.	White matter microstructure in first episode schizophrenia (left anterior cingulate cortex)	93 Han Chinese cases, 134 Han Chinese controls	NA	14q11.2	14	20403486	TEP1	TEP1	NA	NA	ENSG00000129566	NA	NA	rs8009925-?	rs8009925	0	8009925	non_coding_transcript_exon_variant	FALSE	NR	7e-8	7.154901959985743	NA	0.04	unit increase	Illumina [6055918] (imputed)	N	white matter microstructure measurement, cingulate cortex measurement	http://www.ebi.ac.uk/efo/EFO_0005674, http://www.ebi.ac.uk/efo/EFO_0007738	GCST004994	Genome-wide genotyping array	NA	NA	0.04
2017-12-01	28924203	Ren HY	2017-09-18	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/28924203	The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia.	White matter microstructure in first episode schizophrenia (right anterior cingulate cortex)	93 Han Chinese cases, 134 Han Chinese controls	NA	20q13.2	20	51467037	NFATC2	NFATC2	NA	NA	ENSG00000101096	NA	NA	rs193091397-?	rs193091397	0	193091397	intron_variant	FALSE	NR	1e-7	7	NA	2.83	unit decrease	Illumina [6055918] (imputed)	N	white matter microstructure measurement, cingulate cortex measurement	http://www.ebi.ac.uk/efo/EFO_0005674, http://www.ebi.ac.uk/efo/EFO_0007738	GCST004993	Genome-wide genotyping array	NA	2.83	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q36.1	7	148932667	EZH2	RN7SL569P - RNY4	ENSG00000239468	ENSG00000252316	NA	42154	30648	rs822531-T	rs822531	0	822531	intergenic_variant	TRUE	0.7837	2e-6	5.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7837	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q35.1	5	171854871	FBXW11	SMIM23 - FBXW11	ENSG00000185662	ENSG00000072803	NA	58745	6678	rs4868125-C	rs4868125	0	4868125	regulatory_region_variant	TRUE	0.3979	6e-7	6.221848749616356	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.3979	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q21.3	5	108816727	FER	FER	NA	NA	ENSG00000151422	NA	NA	rs10041657-A	rs10041657	0	10041657	intron_variant	FALSE	0.2268	1e-8	8	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.2268	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q21.3	5	108816727	FER	FER	NA	NA	ENSG00000151422	NA	NA	rs10041657-A	rs10041657	0	10041657	intron_variant	FALSE	0.2268	3e-6	5.522878745280337	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.2268	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q35.3	5	177100576	FGFR4	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-T	rs6556301	0	6556301	intergenic_variant	TRUE	0.3605	8e-14	13.096910013008056	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.3605	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q35.3	5	177100576	FGFR4	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-T	rs6556301	0	6556301	intergenic_variant	TRUE	0.3605	3e-9	8.522878745280337	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.3605	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q35.3	5	177100576	FGFR4	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-T	rs6556301	0	6556301	intergenic_variant	TRUE	0.3605	2e-6	5.698970004336019	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.3605	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q14.1	6	75528025	FILIP1	RPL26P20 - H3P27	ENSG00000219722	ENSG00000220730	NA	27889	58097	rs12207675-T	rs12207675	0	12207675	intergenic_variant	TRUE	0.8857	2e-10	9.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.8857	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q14.1	6	75528025	FILIP1	RPL26P20 - H3P27	ENSG00000219722	ENSG00000220730	NA	27889	58097	rs12207675-T	rs12207675	0	12207675	intergenic_variant	TRUE	0.8857	5e-7	6.301029995663981	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.8857	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q14.1	6	75528025	FILIP1	RPL26P20 - H3P27	ENSG00000219722	ENSG00000220730	NA	27889	58097	rs12207675-T	rs12207675	0	12207675	intergenic_variant	TRUE	0.8857	7e-6	5.154901959985743	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.8857	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q26.31	3	172204265	FNDC3B	FNDC3B	NA	NA	ENSG00000075420	NA	NA	rs12493901-A	rs12493901	0	12493901	intron_variant	FALSE	0.4712	6e-13	12.221848749616356	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.4712	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q26.31	3	172204265	FNDC3B	FNDC3B	NA	NA	ENSG00000075420	NA	NA	rs12493901-A	rs12493901	0	12493901	intron_variant	FALSE	0.4712	6e-9	8.221848749616356	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.4712	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7p22.3	7	2750246	GNA12	AMZ1, GNA12	NA	NA	ENSG00000174945, ENSG00000146535	NA	NA	rs798502-A	rs798502	0	798502	intron_variant	FALSE	0.7108	1e-6	6	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7108	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7p22.3	7	2750246	GNA12	AMZ1, GNA12	NA	NA	ENSG00000174945, ENSG00000146535	NA	NA	rs798502-A	rs798502	0	798502	intron_variant	FALSE	0.7108	6e-6	5.221848749616356	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.7108	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q24.2	6	142358435	GPR126	ADGRG6	NA	NA	ENSG00000112414	NA	NA	rs6570507-A	rs6570507	0	6570507	intron_variant	FALSE	0.3186	2e-11	10.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.3186	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q24.2	6	142358435	GPR126	ADGRG6	NA	NA	ENSG00000112414	NA	NA	rs6570507-A	rs6570507	0	6570507	intron_variant	FALSE	0.3186	2e-8	7.698970004336019	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.3186	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2q24.3	2	164656581	GRB14, COBLL1	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs10195252-T	rs10195252	0	10195252	intron_variant	FALSE	0.5727	1e-13	13	(women)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.5727	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8q24.21	8	129724451	GSDMC	CCDC26 - MTRF1LP2	ENSG00000229140	ENSG00000224110	NA	40681	4293	rs6470765-A	rs6470765	0	6470765	intergenic_variant	TRUE	NR	9e-11	10.045757490560675	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	NA	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2q37.3	2	241297557	HDLBP	HDLBP	NA	NA	ENSG00000115677	NA	NA	rs6743226-C	rs6743226	0	6743226	intron_variant	FALSE	NR	3e-11	10.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	NA	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	4q31.21	4	144653692	HHIP	HHIP-AS1, HHIP	NA	NA	ENSG00000248890, ENSG00000164161	NA	NA	rs1812175-A	rs1812175	0	1812175	intron_variant	FALSE	0.1839	5e-7	6.301029995663981	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.1839	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	4q31.21	4	144653692	HHIP	HHIP-AS1, HHIP	NA	NA	ENSG00000248890, ENSG00000164161	NA	NA	rs1812175-A	rs1812175	0	1812175	intron_variant	FALSE	0.1839	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.1839	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p22.2	6	26267527	HIST1H3G, HIST1H2BH	H2BC9 - H3C8	ENSG00000275713	ENSG00000273983	NA	13817	1878	rs7773004-A	rs7773004	0	7773004	intergenic_variant	TRUE	0.4885	1e-10	10	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.4885	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p22.2	6	26267527	HIST1H3G, HIST1H2BH	H2BC9 - H3C8	ENSG00000275713	ENSG00000273983	NA	13817	1878	rs7773004-A	rs7773004	0	7773004	intergenic_variant	TRUE	0.4885	1e-8	8	(men)	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.4885	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1q41	1	221136075	HLX	NA	NA	NA	NA	NA	NA	rs12127195-A	rs12127195	0	12127195	intergenic_variant	TRUE	0.3148	3e-6	5.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.3148	NA	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6p21.31	6	34227234	HMGA1	CYCSP55 - HMGA1	ENSG00000214810	ENSG00000137309	NA	7168	9639	rs1776897-T	rs1776897	0	1776897	regulatory_region_variant	TRUE	0.8414	2e-16	15.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789	GCST004501	Genome-wide genotyping array	0.8414	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	18q11.2	18	23147647	CABLES1	CABLES1	NA	NA	ENSG00000134508	NA	NA	rs4800452-?	rs4800452	0	4800452	intron_variant	FALSE	0.7873	4e-11	10.397940008672037	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7873	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p36.13	1	16981663	MFAP2	MFAP2 - ATP13A2	ENSG00000117122	ENSG00000159363	NA	1031	4295	rs9435732-?	rs9435732	0	9435732	intron_variant	TRUE	0.7313000000000001	6e-6	5.221848749616356	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7313000000000001	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118321979	SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126	NA	57490	292354	rs7536458-?	rs7536458	0	7536458	intergenic_variant	TRUE	0.7428	1e-6	6	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7428	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118961220	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs984222-?	rs984222	0	984222	intron_variant	FALSE	0.6225	5e-14	13.301029995663981	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6225	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q21.2	1	149934520	MTMR11	MTMR11	NA	NA	ENSG00000014914	NA	NA	rs11205303-?	rs11205303	0	11205303	missense_variant	FALSE	0.3839	1e-7	7	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3839	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q24.3	1	172361919	DNM3	DNM3	NA	NA	ENSG00000197959	NA	NA	rs1894633-?	rs1894633	0	1894633	intron_variant	FALSE	0.3388	6e-10	9.221848749616356	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3388	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.3	1	184054395	TSEN15	TSEN15	NA	NA	ENSG00000198860	NA	NA	rs1046934-?	rs1046934	0	1046934	missense_variant	FALSE	0.35729999999999995	2e-8	7.698970004336019	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.35729999999999995	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2q24.3	2	164656581	GRB14, COBLL1	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs10195252-?	rs10195252	0	10195252	intron_variant	FALSE	0.5932	1e-12	12	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.5932	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p21.1	3	52615732	PBRM1	PBRM1	NA	NA	ENSG00000163939	NA	NA	rs13083798-?	rs13083798	0	13083798	intron_variant	FALSE	0.4905	1e-10	10	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.4905	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p14.1	3	64744216	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs7638389-?	rs7638389	0	7638389	intron_variant	FALSE	0.7481	2e-12	11.698970004336019	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.7481	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q25.31	3	157079820	LEKR1	LEKR1 - LINC00880	ENSG00000197980	ENSG00000243629	NA	33691	1847	rs17451107-?	rs17451107	0	17451107	regulatory_region_variant	TRUE	0.6097	3e-12	11.522878745280337	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6097	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4q21.21	4	81228677	PRKG2	PRKG2 - NA	ENSG00000138669	NA	NA	13455	NA	rs710841-?	rs710841	0	710841	intergenic_variant	TRUE	0.2519	6e-6	5.221848749616356	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2519	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5p13.3	5	32753566	NPR3	NPR3	NA	NA	ENSG00000113389	NA	NA	rs2062708-?	rs2062708	0	2062708	intron_variant	FALSE	0.16169999999999995	5e-6	5.301029995663981	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.16169999999999995	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q11.2	5	56565039	MAP3K1	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs3936510-?	rs3936510	0	3936510	intron_variant	FALSE	0.1867	6e-13	12.221848749616356	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.1867	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q35.1	5	171856465	FBXW11	SMIM23 - FBXW11	ENSG00000185662	ENSG00000072803	NA	60339	5084	rs4868126-?	rs4868126	0	4868126	regulatory_region_variant	TRUE	0.6084	3e-7	6.522878745280337	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6084	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q35.3	5	177100576	FGFR4	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-?	rs6556301	0	6556301	intergenic_variant	TRUE	0.3576	6e-8	7.221848749616356	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.3576	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p22.2	6	26200449	HIST1H2BF	H2BC7	NA	NA	ENSG00000277224	NA	NA	rs806794-?	rs806794	0	806794	3_prime_UTR_variant	FALSE	0.6986	4e-6	5.3979400086720375	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6986	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.31	6	34231315	CYCSL1, HMGA1	CYCSP55 - HMGA1	ENSG00000214810	ENSG00000137309	NA	11249	5558	rs2780226-?	rs2780226	0	2780226	regulatory_region_variant	TRUE	0.0816	1e-10	10	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.0816	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.1	6	43790159	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	3672	54719	rs998584-?	rs998584	0	998584	regulatory_region_variant	TRUE	0.486	3e-25	24.522878745280337	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.486	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q16.3	6	104916546	HACE1	LIN28B-AS1	NA	NA	ENSG00000203809	NA	NA	rs11156429-?	rs11156429	0	11156429	intron_variant	FALSE	0.4566	9e-7	6.045757490560675	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.4566	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q22.33	6	127111512	RSPO3	NA - RSPO3	NA	ENSG00000146374	NA	NA	7159	rs1936797-?	rs1936797	0	1936797	intron_variant	TRUE	0.28890000000000005	3e-11	10.522878745280337	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.28890000000000005	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q24.2	6	142382740	GPR126	ADGRG6	NA	NA	ENSG00000112414	NA	NA	rs4896582-?	rs4896582	0	4896582	intron_variant	FALSE	0.6960999999999999	2e-6	5.698970004336019	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6960999999999999	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	25817905	UBA52P1	NA	NA	NA	NA	NA	NA	rs4141278-?	rs4141278	0	4141278	intergenic_variant	TRUE	0.19799999999999995	2e-11	10.698970004336019	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.19799999999999995	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.1	7	28150327	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs1708299-?	rs1708299	0	1708299	intron_variant	FALSE	0.2994	1e-6	6	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.2994	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7q32.2	7	130373797	CPA5	CPA5 - CPA1	ENSG00000158525	ENSG00000091704	NA	5067	6542	rs1465370-?	rs1465370	0	1465370	regulatory_region_variant	TRUE	0.6767000000000001	1e-7	7	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004563	Genome-wide genotyping array	0.6767000000000001	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	18q21.1	18	46265918	C18orf25	C18orf25	NA	NA	ENSG00000152242	NA	NA	rs3842397-C	rs3842397	0	3842397	3_prime_UTR_variant	FALSE	0.5523	2e-13	12.698970004336019	NA	0.02677698	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5523	NA	0.02677698
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	18q21.33	18	63253621	BCL2	BCL2	NA	NA	ENSG00000171791	NA	NA	rs17758695-T	rs17758695	0	17758695	intron_variant	FALSE	0.0303	8e-14	13.096910013008056	NA	0.07937635	[0.059-0.1] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0303	NA	0.07937635
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	18q22.2	18	69872156	CD226	CD226	NA	NA	ENSG00000150637	NA	NA	rs1865761-C	rs1865761	0	1865761	intron_variant	FALSE	0.521	4e-117	116.39794000867204	NA	0.08320315	[0.076-0.09] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.521	NA	0.08320315
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	18q22.2	18	69934400	CD226	CD226	NA	NA	ENSG00000150637	NA	NA	rs1823778-C	rs1823778	0	1823778	intron_variant	FALSE	0.8685	9e-13	12.045757490560675	NA	0.03846836	[0.028-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.8685	NA	0.03846836
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	18q22.2	18	70023957	RTTN	RTTN	NA	NA	ENSG00000176225	NA	NA	rs185898-A	rs185898	0	185898	intron_variant	FALSE	0.0106	1e-39	39	NA	0.2333282	[0.2-0.27] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0106	NA	0.2333282
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	18q23	18	79472709	NFATC1	NFATC1	NA	NA	ENSG00000131196	NA	NA	rs160189-G	rs160189	0	160189	intron_variant	FALSE	0.3158	8e-15	14.096910013008056	NA	0.03051198	[0.023-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3158	NA	0.03051198
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19p13.3	19	1033560	CNN2	CNN2	NA	NA	ENSG00000064666	NA	NA	rs4807455-A	rs4807455	0	4807455	intron_variant	FALSE	0.2578	1e-11	11	NA	0.02862183	[0.02-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2578	NA	0.02862183
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19p13.3	19	1074316	HMHA1	ARHGAP45	NA	NA	ENSG00000180448	NA	NA	rs12974537-T	rs12974537	0	12974537	intron_variant	FALSE	0.093	1e-12	12	NA	0.0445208	[0.032-0.057] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.093	NA	0.0445208
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19p13.3	19	6011130	RFX2, CTC-232P5.1	RFX2, RANBP3-DT	NA	NA	ENSG00000087903, ENSG00000266983	NA	NA	rs505401-T	rs505401	0	505401	intron_variant	FALSE	0.1056	2e-10	9.698970004336019	NA	0.03842616	[0.027-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1056	NA	0.03842616
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19p13.3	19	6801955	VAV1	VAV1	NA	NA	ENSG00000141968	NA	NA	rs332426-A	rs332426	0	332426	intron_variant	FALSE	0.1013	4e-10	9.397940008672037	NA	0.03756262	[0.026-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1013	NA	0.03756262
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19p13.3	19	6802560	VAV1	VAV1	NA	NA	ENSG00000141968	NA	NA	rs8106212-T	rs8106212	0	8106212	intron_variant	FALSE	0.0124	2e-12	11.698970004336019	NA	0.1172424	[0.085-0.15] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0124	NA	0.1172424
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19p13.12	19	14381257	CD97	ADGRE5	NA	NA	ENSG00000123146	NA	NA	rs111896493-CTGAG	rs111896493	0	111896493	5_prime_UTR_variant	FALSE	0.4358	4e-9	8.397940008672037	NA	0.02341667	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4358	NA	0.02341667
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19p13.12	19	16086611	TPM4	TPM4	NA	NA	ENSG00000167460	NA	NA	rs2303149-G	rs2303149	0	2303149	intron_variant	FALSE	0.4596	6e-10	9.221848749616356	NA	0.0235933	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4596	NA	0.0235933
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19p13.11	19	16100820	TPM4	TPM4	NA	NA	ENSG00000167460	NA	NA	rs59508494-G	rs59508494	0	59508494	non_coding_transcript_exon_variant	FALSE	0.0191	1e-67	67	NA	0.2421656	[0.21-0.27] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0191	NA	0.2421656
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19p13.11	19	16106643	RAB8A, CTD-2231E14.5	TPM4 - RAB8A	ENSG00000167460	ENSG00000167461	NA	3641	5246	rs2113036-C	rs2113036	0	2113036	regulatory_region_variant	TRUE	0.3438	1e-28	28	NA	0.04338882	[0.036-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3438	NA	0.04338882
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19p13.11	19	17091936	MYO9B	MYO9B	NA	NA	ENSG00000099331	NA	NA	rs7254827-T	rs7254827	0	7254827	intron_variant	FALSE	0.2235	3e-17	16.522878745280337	NA	0.0365937	[0.028-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2235	NA	0.0365937
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19q13.11	19	32582525	PDCD5	PDCD5	NA	NA	ENSG00000105185	NA	NA	rs4499344-A	rs4499344	0	4499344	intron_variant	FALSE	0.2943	3e-9	8.522878745280337	NA	0.02367493	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2943	NA	0.02367493
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19q13.12	19	35171354	FXYD5	FXYD5 - FAM187B	ENSG00000089327	ENSG00000177558	NA	1473	53446	rs7249578-A	rs7249578	0	7249578	regulatory_region_variant	TRUE	0.4195	1e-14	14	NA	0.02866287	[0.021-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4195	NA	0.02866287
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19q13.2	19	38304255	C19orf33	YIF1B, C19orf33	NA	NA	ENSG00000167645, ENSG00000167644	NA	NA	rs2304176-C	rs2304176	0	2304176	5_prime_UTR_variant	FALSE	0.2248	9e-12	11.045757490560675	NA	0.02958239	[0.021-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2248	NA	0.02958239
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19q13.31	19	44644040	PVR	PVR, CEACAM16-AS1	NA	NA	ENSG00000073008, ENSG00000266903	NA	NA	rs11540084-T	rs11540084	0	11540084	5_prime_UTR_variant	FALSE	0.1974	1e-17	17	NA	0.03882636	[0.03-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1974	NA	0.03882636
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19q13.31	19	44658770	PVR	PVR, CEACAM16-AS1	NA	NA	ENSG00000073008, ENSG00000266903	NA	NA	rs203710-G	rs203710	0	203710	missense_variant	FALSE	0.972	1e-9	9	NA	0.06694429	[0.045-0.088] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.972	NA	0.06694429
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19q13.32	19	44869072	PVRL2	NECTIN2	NA	NA	ENSG00000130202	NA	NA	rs17561351-G	rs17561351	0	17561351	intron_variant	FALSE	0.0583	6e-10	9.221848749616356	NA	0.0449143	[0.031-0.059] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0583	NA	0.0449143
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19q13.32	19	45212934	EXOC3L2	MARK4, BLOC1S3, EXOC3L2	NA	NA	ENSG00000007047, ENSG00000189114, ENSG00000283632	NA	NA	rs11667509-C	rs11667509	0	11667509	3_prime_UTR_variant	FALSE	0.378	6e-78	77.22184874961636	NA	0.07079251	[0.063-0.078] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.378	NA	0.07079251
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19q13.33	19	48728969	RASIP1	RASIP1	NA	NA	ENSG00000105538	NA	NA	rs2287922-A	rs2287922	0	2287922	missense_variant	FALSE	0.5342	1e-11	11	NA	0.02448993	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5342	NA	0.02448993
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	19q13.42	19	55025227	GP6	GP6-AS1, GP6, GP6, GP6, GP6, GP6, GP6, GP6, GP6, GP6, GP6	NA	NA	ENSG00000267265, ENSG00000275633, ENSG00000278316, ENSG00000275931, ENSG00000277439, ENSG00000278670, ENSG00000274050, ENSG00000276065, ENSG00000276211, ENSG00000274566, ENSG00000088053	NA	NA	rs1613662-A	rs1613662	0	1613662	missense_variant	FALSE	0.833	9e-28	27.045757490560675	NA	0.05273665	[0.043-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.833	NA	0.05273665
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	14q32.12	14	92651884	RIN3	RIN3	NA	NA	ENSG00000100599	NA	NA	rs117068593-T	rs117068593	0	117068593	missense_variant	FALSE	0.169	3e-6	5.522878745280337	NA	0.06	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.169	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78533838	AGPHD1	HYKK	NA	NA	ENSG00000188266	NA	NA	rs931794-A	rs931794	0	931794	3_prime_UTR_variant	FALSE	0.407	2e-11	10.698970004336019	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.407	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144445825	Intergenic	TET2 - NA	ENSG00000168769	NA	NA	39166009	NA	rs17019354-T	rs17019354	0	17019354	intron_variant	TRUE	0.278	3e-9	8.522878745280337	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.278	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144341775	Intergenic	NA	NA	NA	NA	NA	NA	rs13105210-T	rs13105210	0	13105210	intron_variant	TRUE	0.281	3e-9	8.522878745280337	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.281	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78528674	AGPHD1	HYKK	NA	NA	ENSG00000188266	NA	NA	rs12441354-A	rs12441354	0	12441354	3_prime_UTR_variant	FALSE	0.219	7e-9	8.154901959985743	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.219	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78616223	CHRNA3	CHRNA3	NA	NA	ENSG00000080644	NA	NA	rs28681284-T	rs28681284	0	28681284	intron_variant	FALSE	0.185	2e-7	6.698970004336019	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.185	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128130901	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs34174370-T	rs34174370	0	34174370	intron_variant	FALSE	0.167	3e-7	6.522878745280337	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.167	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128131233	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs11714619-A	rs11714619	0	11714619	intron_variant	FALSE	0.157	5e-7	6.301029995663981	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.157	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128149432	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs73192978-A	rs73192978	0	73192978	intron_variant	FALSE	0.156	5e-7	6.301029995663981	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.156	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128149478	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs73192979-T	rs73192979	0	73192979	intron_variant	FALSE	0.156	5e-7	6.301029995663981	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.156	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128156069	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs11709066-A	rs11709066	0	11709066	intron_variant	FALSE	0.157	6e-7	6.221848749616356	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.157	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128135684	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs35347185-T	rs35347185	0	35347185	intron_variant	FALSE	0.157	6e-7	6.221848749616356	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.157	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128129313	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs13095660-T	rs13095660	0	13095660	intron_variant	FALSE	0.156	6e-7	6.221848749616356	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.156	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128129545	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs6788497-T	rs6788497	0	6788497	intron_variant	FALSE	0.156	6e-7	6.221848749616356	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.156	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	19q13.2	19	40854091	Intergenic	CYP2A6 - CYP2A7	ENSG00000255974	ENSG00000198077	NA	3644	21348	rs3875149-A	rs3875149	0	3875149	intron_variant	TRUE	0.386	6e-7	6.221848749616356	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.386	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128311631	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs73197383-T	rs73197383	0	73197383	intron_variant	FALSE	0.155	6e-7	6.221848749616356	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.155	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128311500	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs56287882-A	rs56287882	0	56287882	intron_variant	FALSE	0.156	6e-7	6.221848749616356	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.156	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128130841	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs13059975-T	rs13059975	0	13059975	intron_variant	FALSE	0.156	7e-7	6.154901959985743	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.156	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128346623	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs61044849-T	rs61044849	0	61044849	intron_variant	FALSE	0.155	7e-7	6.154901959985743	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.155	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	1q41	1	218398662	TGFB2	TGFB2	NA	NA	ENSG00000092969	NA	NA	rs11118102-A	rs11118102	0	11118102	intron_variant	FALSE	0.134	1e-6	6	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.134	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	19q13.2	19	40818449	Intergenic	CYP2F2P	NA	NA	ENSG00000237118	NA	NA	rs189256434-A	rs189256434	1	3213808	non_coding_transcript_exon_variant	FALSE	0.726	2e-6	5.698970004336019	NA	0.061	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.726	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88945562	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs4416442-T	rs4416442	0	4416442	intron_variant	FALSE	0.548	1e-12	12	NA	0.062	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.548	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78448346	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2938670-T	rs2938670	0	2938670	intron_variant	FALSE	0.608	2e-12	11.698970004336019	NA	0.062	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.608	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78448590	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2656052-A	rs2656052	0	2656052	intron_variant	FALSE	0.608	2e-12	11.698970004336019	NA	0.062	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.608	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78521704	AGPHD1	HYKK	NA	NA	ENSG00000188266	NA	NA	rs10519203-A	rs10519203	0	10519203	intron_variant	FALSE	0.637	6e-12	11.221848749616356	NA	0.062	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.637	NA	NA
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8q24.13	8	125478730	NR	TRIB1 - NA	ENSG00000173334	NA	NA	40327	NA	rs2954029-A	rs2954029	0	2954029	intron_variant	TRUE	NR	4e-25	24.397940008672037	NA	0.035	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.035
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8q24.13	8	125479491	NR	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	41088	380230	rs2954031-G	rs2954031	0	2954031	intron_variant	TRUE	0.564	3e-23	22.522878745280337	(EA)	0.037	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.564	NA	0.037
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8q24.13	8	125479491	NR	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	41088	380230	rs2954031-G	rs2954031	0	2954031	intron_variant	TRUE	NR	3e-25	24.522878745280337	NA	0.036	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.036
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8q24.13	8	125483576	NR	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	45173	376145	rs10808546-C	rs10808546	0	10808546	intron_variant	TRUE	0.56	1e-23	23	(EA)	0.038	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.56	NA	0.038
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8q24.13	8	125483576	NR	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	45173	376145	rs10808546-C	rs10808546	0	10808546	intron_variant	TRUE	NR	8e-23	22.096910013008056	NA	0.034	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.034
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8q24.13	8	125494452	NR	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	56049	365269	rs112875651-G	rs112875651	0	112875651	intron_variant	TRUE	0.62	8e-19	18.096910013008056	(EA)	0.036	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.62	NA	0.036
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8q24.13	8	125494452	NR	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	56049	365269	rs112875651-G	rs112875651	0	112875651	intron_variant	TRUE	NR	8e-17	16.096910013008056	NA	0.031	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.031
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9p22.3	9	15293118	NR	TTC39B	NA	NA	ENSG00000155158	NA	NA	rs486349-G	rs486349	0	486349	intron_variant	FALSE	0.131	7e-15	14.154901959985743	(EA)	0.044	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.131	NA	0.044
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9p22.3	9	15293118	NR	TTC39B	NA	NA	ENSG00000155158	NA	NA	rs486349-G	rs486349	0	486349	intron_variant	FALSE	NR	2e-16	15.698970004336019	NA	0.044	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.044
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9p22.3	9	15294598	NR	TTC39B	NA	NA	ENSG00000155158	NA	NA	rs540885-G	rs540885	0	540885	intron_variant	FALSE	0.136	1e-13	13	(EA)	0.041	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.136	NA	0.041
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9p22.3	9	15294598	NR	TTC39B	NA	NA	ENSG00000155158	NA	NA	rs540885-G	rs540885	0	540885	intron_variant	FALSE	NR	3e-15	14.522878745280337	NA	0.041	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.041
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9p22.3	9	15296036	NR	TTC39B	NA	NA	ENSG00000155158	NA	NA	rs643531-C	rs643531	0	643531	intron_variant	FALSE	0.137	2e-13	12.698970004336019	(EA)	0.04	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.137	NA	0.04
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9p22.3	9	15296036	NR	TTC39B	NA	NA	ENSG00000155158	NA	NA	rs643531-C	rs643531	0	643531	intron_variant	FALSE	NR	2e-15	14.698970004336019	NA	0.041	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.041
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9p22.3	9	15298668	NR	TTC39B	NA	NA	ENSG00000155158	NA	NA	rs675849-T	rs675849	0	675849	intron_variant	FALSE	0.141	6e-13	12.221848749616356	(EA)	0.039	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.141	NA	0.039
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9p22.3	9	15298668	NR	TTC39B	NA	NA	ENSG00000155158	NA	NA	rs675849-T	rs675849	0	675849	intron_variant	FALSE	NR	3e-14	13.522878745280337	NA	0.039	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.039
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9p22.3	9	15305380	NR	TTC39B	NA	NA	ENSG00000155158	NA	NA	rs581080-G	rs581080	0	581080	intron_variant	FALSE	0.182	6e-11	10.221848749616356	(EA)	0.033	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.182	NA	0.033
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9p22.3	9	15305380	NR	TTC39B	NA	NA	ENSG00000155158	NA	NA	rs581080-G	rs581080	0	581080	intron_variant	FALSE	NR	2e-12	11.698970004336019	NA	0.033	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.033
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9q31.1	9	104828991	NR	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs2853579-G	rs2853579	0	2853579	missense_variant	FALSE	0.874	6e-16	15.221848749616356	(EA)	0.046	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.874	NA	0.046
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9q31.1	9	104828991	NR	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs2853579-G	rs2853579	0	2853579	missense_variant	FALSE	NR	2e-20	19.69897000433602	NA	0.044	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.044
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9q31.1	9	104839260	NR	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs2472386-G	rs2472386	0	2472386	intron_variant	FALSE	0.658	9e-7	6.045757490560675	(EA)	0.019	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.658	NA	0.019
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9q31.1	9	104839260	NR	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs2472386-G	rs2472386	0	2472386	intron_variant	FALSE	0.586	8e-7	6.096910013008056	(Hispanic)	0.062	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.586	NA	0.062
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9q31.1	9	104839260	NR	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs2472386-G	rs2472386	0	2472386	intron_variant	FALSE	NR	1e-11	11	NA	0.024	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.024
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9q31.1	9	104884738	NR	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs11789603-C	rs11789603	0	11789603	intron_variant	FALSE	0.893	7e-27	26.154901959985743	(EA)	0.065	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.893	NA	0.065
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9q31.1	9	104884738	NR	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs11789603-C	rs11789603	0	11789603	intron_variant	FALSE	NR	9e-29	28.045757490560675	NA	0.062	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.062
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	9q31.1	9	104886314	NR	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs3847302-A	rs3847302	0	3847302	intron_variant	FALSE	0.877	6e-36	35.221848749616356	(EA)	0.072	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.877	NA	0.072
2017-06-29	28360221	Boger CA	2017-03-30	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/28360221	NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.	Blood osmolality (transformed sodium)	45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals	17,637 European ancestry individuals	16q22.1	16	69703565	NFAT5, NQO1, NOB1, CYB5B	NFAT5	NA	NA	ENSG00000102908	NA	NA	rs9980-G	rs9980	0	9980	3_prime_UTR_variant	FALSE	0.14	6e-12	11.221848749616356	NA	0.06	unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	blood osmolality measurement	http://www.ebi.ac.uk/efo/EFO_0007967	GCST004267	Genome-wide genotyping array	0.14	NA	NA
2017-06-29	28360221	Boger CA	2017-03-30	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/28360221	NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.	Blood osmolality (transformed sodium)	45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals	17,637 European ancestry individuals	2q24.2	2	161709535	DPP4, SLC4A10	SLC4A10	NA	NA	ENSG00000144290	NA	NA	rs16846053-G	rs16846053	0	16846053	intron_variant	FALSE	0.1	7e-8	7.154901959985743	(EA)	0.05	unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	blood osmolality measurement	http://www.ebi.ac.uk/efo/EFO_0007967	GCST004267	Genome-wide genotyping array	0.1	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.1	6	43790159	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	3672	54719	rs998584-A	rs998584	0	998584	regulatory_region_variant	TRUE	0.4738	3e-14	13.522878745280337	NA	0.0295	[0.022-0.037] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.4738	NA	0.0295
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q14.1	6	80144753	BCKDHB	BCKDHB	NA	NA	ENSG00000083123	NA	NA	rs10080237-T	rs10080237	0	10080237	intron_variant	FALSE	0.5627	5e-8	7.301029995663981	NA	0.0219	[0.014-0.03] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5627	NA	0.0219
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q16.3	6	104931079	LIN28B	LIN28B-AS1	NA	NA	ENSG00000203809	NA	NA	rs7759938-C	rs7759938	0	7759938	intron_variant	FALSE	0.33030000000000004	3e-15	14.522878745280337	NA	0.0302	[0.023-0.038] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.33030000000000004	NA	0.0302
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q22.33	6	127133993	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs7766106-T	rs7766106	0	7766106	intron_variant	FALSE	0.4766	1e-9	9	NA	0.0213	[0.014-0.028] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.4766	NA	0.0213
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q24.2	6	142382740	GPR126	ADGRG6	NA	NA	ENSG00000112414	NA	NA	rs4896582-G	rs4896582	0	4896582	intron_variant	FALSE	0.675	1e-13	13	NA	0.0284	[0.021-0.036] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.675	NA	0.0284
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p22.3	7	2762169	AMZ1	GNA12, AMZ1	NA	NA	ENSG00000146535, ENSG00000174945	NA	NA	rs798489-C	rs798489	0	798489	splice_donor_variant	FALSE	0.7155	8e-8	7.096910013008056	NA	0.0221	[0.014-0.03] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7155	NA	0.0221
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p21.1	7	20391962	ITGB8	ITGB8	NA	NA	ENSG00000105855	NA	NA	rs10231365-T	rs10231365	0	10231365	intron_variant	FALSE	0.511	2e-8	7.698970004336019	NA	0.0226	[0.015-0.03] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.511	NA	0.0226
2017-06-29	28360221	Boger CA	2017-03-30	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/28360221	NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.	Blood osmolality (transformed sodium)	45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals	17,637 European ancestry individuals	2p11.2	2	85532004	NR	RPSAP22 - PARTICL	ENSG00000229648	ENSG00000286532	NA	40224	5458	rs17026396-T	rs17026396	0	17026396	intergenic_variant	TRUE	0.62	3e-6	5.522878745280337	(Asian)	0.07	[0.039-0.101] unit decrease	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	blood osmolality measurement	http://www.ebi.ac.uk/efo/EFO_0007967	GCST004267	Genome-wide genotyping array	0.62	NA	NA
2017-06-29	28360221	Boger CA	2017-03-30	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/28360221	NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.	Blood osmolality (transformed sodium)	45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals	17,637 European ancestry individuals	2q35	2	215107337	NR	ABCA12	NA	NA	ENSG00000144452	NA	NA	rs2970963-T	rs2970963	0	2970963	intron_variant	FALSE	0.97	6e-6	5.221848749616356	(Asian)	0.32	[0.18-0.46] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	blood osmolality measurement	http://www.ebi.ac.uk/efo/EFO_0007967	GCST004267	Genome-wide genotyping array	0.97	NA	NA
2017-06-29	28360221	Boger CA	2017-03-30	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/28360221	NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.	Blood osmolality (transformed sodium)	45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals	17,637 European ancestry individuals	4q32.1	4	158177632	NR	FAM198B-AS1	NA	NA	ENSG00000248429	NA	NA	rs13126694-A	rs13126694	0	13126694	intron_variant	FALSE	0.63	9e-6	5.045757490560675	(Asian)	0.08	[0.047-0.113] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	blood osmolality measurement	http://www.ebi.ac.uk/efo/EFO_0007967	GCST004267	Genome-wide genotyping array	0.63	NA	NA
2017-06-29	28360221	Boger CA	2017-03-30	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/28360221	NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.	Blood osmolality (transformed sodium)	45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals	17,637 European ancestry individuals	5q34	5	164221345	NR	NA	NA	NA	NA	NA	NA	rs12518453-A	rs12518453	0	12518453	intron_variant	TRUE	0.97	4e-7	6.3979400086720375	(Asian)	0.39	[0.24-0.54] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	blood osmolality measurement	http://www.ebi.ac.uk/efo/EFO_0007967	GCST004267	Genome-wide genotyping array	0.97	NA	NA
2017-06-29	28360221	Boger CA	2017-03-30	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/28360221	NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.	Blood osmolality (transformed sodium)	45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals	17,637 European ancestry individuals	6q14.2	6	84004417	NR	CYB5R4 - LINC02857	ENSG00000065615	ENSG00000230852	NA	36994	14787	rs215970-A	rs215970	0	215970	intron_variant	TRUE	0.97	2e-6	5.698970004336019	(Asian)	0.36	[0.21-0.51] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	blood osmolality measurement	http://www.ebi.ac.uk/efo/EFO_0007967	GCST004267	Genome-wide genotyping array	0.97	NA	NA
2017-06-29	28360221	Boger CA	2017-03-30	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/28360221	NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.	Blood osmolality (transformed sodium)	45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals	17,637 European ancestry individuals	6q16.3	6	101391987	NR	GRIK2	NA	NA	ENSG00000164418	NA	NA	rs6930752-A	rs6930752	0	6930752	intron_variant	FALSE	0.64	9e-6	5.045757490560675	(Asian)	0.08	[0.047-0.113] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	blood osmolality measurement	http://www.ebi.ac.uk/efo/EFO_0007967	GCST004267	Genome-wide genotyping array	0.64	NA	NA
2017-06-29	28360221	Boger CA	2017-03-30	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/28360221	NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.	Blood osmolality (transformed sodium)	45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals	17,637 European ancestry individuals	6q23.3	6	135568667	NR	LINC00271	NA	NA	ENSG00000231028	NA	NA	rs12663042-A	rs12663042	0	12663042	intron_variant	FALSE	0.02	7e-6	5.154901959985743	(Asian)	0.45	[0.25-0.65] unit decrease	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	blood osmolality measurement	http://www.ebi.ac.uk/efo/EFO_0007967	GCST004267	Genome-wide genotyping array	0.02	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q31.1	2	174762320	NR	CHRNA1; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2600685-T; rs2600683-C; rs935863-A	rs2600685; rs2600683; rs935863	0	NA	intron_variant; intron_variant; non_coding_transcript_exon_variant	NA	0.527	1e-6	6	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.527	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q31.1	2	175131768	NR	ATF2; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7571171-G; rs2541066-C; rs2178329-G; rs13006117-T; rs13388308-T; rs7566401-C; rs1153684-G; rs21818-G; rs1153672-A; rs13383680-T; rs3771928-G; rs1433236-G; rs1153681-G; rs1153676-A; rs10183675-C; rs17270532-C; rs11888507-T; rs11894840-C	rs7571171; rs2541066; rs2178329; rs13006117; rs13388308; rs7566401; rs1153684; rs21818; rs1153672; rs13383680; rs3771928; rs1433236; rs1153681; rs1153676; rs10183675; rs17270532; rs11888507; rs11894840	0	NA	intron_variant; intron_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; TF_binding_site_variant; intron_variant; intron_variant; intron_variant	NA	0.0	3e-10	9.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q31.1	2	175131768	NR	ATF2; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7571171-G; rs2541066-C; rs2178329-G; rs13006117-T; rs13388308-T; rs7566401-C; rs1153684-G; rs21818-G; rs1153672-A; rs13383680-T; rs3771928-G; rs1433236-G; rs1153681-A; rs1153676-A; rs10183675-C; rs17270532-C; rs11888507-T; rs11894840-C	rs7571171; rs2541066; rs2178329; rs13006117; rs13388308; rs7566401; rs1153684; rs21818; rs1153672; rs13383680; rs3771928; rs1433236; rs1153681; rs1153676; rs10183675; rs17270532; rs11888507; rs11894840	0	NA	intron_variant; intron_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; TF_binding_site_variant; intron_variant; intron_variant; intron_variant	NA	0.11	1e-7	7	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.11	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q31.2	2	178761290	NR	TTN-AS1; TTN; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7604033-C; rs10497522-C; rs2291313-T; rs11902709-C; rs2291311-T; rs4894044-G; rs10497523-G; rs2054708-T; rs1484116-C; rs10171049-G; rs3754953-A; rs4471922-G; rs11895382-T; rs4894037-A; rs2291312-T; rs7600001-C	rs7604033; rs10497522; rs2291313; rs11902709; rs2291311; rs4894044; rs10497523; rs2054708; rs1484116; rs10171049; rs3754953; rs4471922; rs11895382; rs4894037; rs2291312; rs7600001	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; missense_variant; intron_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; missense_variant; intron_variant	NA	0.0	2e-12	11.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q31.2	2	178761290	NR	TTN-AS1; TTN; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7604033-C; rs10497522-C; rs2291313-T; rs11902709-C; rs2291311-T; rs4894044-A; rs10497523-G; rs2054708-T; rs1484116-C; rs10171049-G; rs3754953-A; rs4471922-G; rs11895382-T; rs4894037-A; rs2291312-T; rs7600001-C	rs7604033; rs10497522; rs2291313; rs11902709; rs2291311; rs4894044; rs10497523; rs2054708; rs1484116; rs10171049; rs3754953; rs4471922; rs11895382; rs4894037; rs2291312; rs7600001	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; missense_variant; intron_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; missense_variant; intron_variant	NA	0.141	4e-7	6.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.141	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q34	2	211676652	NR	ERBB4; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10207288-T; rs10174084-A; rs13019783-T; rs4673628-A; rs4423543-G; rs6759039-A	rs10207288; rs10174084; rs13019783; rs4673628; rs4423543; rs6759039	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.002	5e-38	37.30102999566398	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.002	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q34	2	211676652	NR	ERBB4; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10207288-T; rs10174084-A; rs13019783-T; rs4673628-G; rs4423543-G; rs6759039-A	rs10207288; rs10174084; rs13019783; rs4673628; rs4423543; rs6759039	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.464	2e-24	23.69897000433602	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.464	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q35	2;2	216257041;216260591	NR	LINC01963 - MARCHF4; No mapped genes; No mapped genes; MARCHF4; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs207865-A; rs3843344-T; rs207811-G; rs721774-G; rs10490364-C; rs207866-G; rs17822276-G; rs207822-C; rs207808-C; rs117448-G	rs207865; rs3843344; rs207811; rs721774; rs10490364; rs207866; rs17822276; rs207822; rs207808; rs117448	0	NA	intergenic_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intergenic_variant	NA	0.288	2e-16	15.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.288	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q35	2;2	216257041;216260591	NR	LINC01963 - MARCHF4; No mapped genes; No mapped genes; MARCHF4; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs207865-A; rs3843344-T; rs207811-G; rs721774-A; rs10490364-C; rs207866-G; rs17822276-G; rs207822-C; rs207808-C; rs117448-G	rs207865; rs3843344; rs207811; rs721774; rs10490364; rs207866; rs17822276; rs207822; rs207808; rs117448	0	NA	intergenic_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intergenic_variant	NA	0.087	1e-15	15	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.087	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q35	2;2	218688745;218693015	NR	STK36; STK36; No mapped genes	NA	NA	NA	NA	NA	rs16859180-C; rs2303566-A; rs1863704-G	rs16859180; rs2303566; rs1863704	0	NA	missense_variant; intron_variant; missense_variant	NA	0.0	3e-6	5.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q35	2	220437462	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12623312-G; rs11888884-G; rs13411863-G; rs6727716-T; rs12994582-A; rs10180439-G; rs16861204-G; rs17611748-C; rs6436210-C; rs17577244-T; rs4629147-C; rs10498079-G; rs4450588-C; rs2068114-G; rs7572239-C	rs12623312; rs11888884; rs13411863; rs6727716; rs12994582; rs10180439; rs16861204; rs17611748; rs6436210; rs17577244; rs4629147; rs10498079; rs4450588; rs2068114; rs7572239	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	2e-11	10.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q35	2	220437462	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12623312-G; rs11888884-G; rs13411863-G; rs6727716-T; rs12994582-A; rs10180439-G; rs16861204-G; rs17611748-C; rs6436210-C; rs17577244-T; rs4629147-T; rs10498079-G; rs4450588-C; rs2068114-G; rs7572239-C	rs12623312; rs11888884; rs13411863; rs6727716; rs12994582; rs10180439; rs16861204; rs17611748; rs6436210; rs17577244; rs4629147; rs10498079; rs4450588; rs2068114; rs7572239	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.135	8e-6	5.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.135	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q36.1	2;2	221474691;221473195	NR	EPHA4; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; EPHA4	NA	NA	NA	NA	NA	rs3770150-C; rs975194-A; rs1430213-G; rs3821025-A; rs17379786-C; rs1430214-G; rs3770155-C; rs3770154-G	rs3770150; rs975194; rs1430213; rs3821025; rs17379786; rs1430214; rs3770155; rs3770154	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.08	4e-13	12.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.08	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q36.1	2;2	221474691;221473195	NR	EPHA4; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; EPHA4	NA	NA	NA	NA	NA	rs3770150-C; rs975194-A; rs1430213-G; rs3821025-A; rs17379786-C; rs1430214-G; rs3770155-T; rs3770154-G	rs3770150; rs975194; rs1430213; rs3821025; rs17379786; rs1430214; rs3770155; rs3770154	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.469	2e-9	8.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.469	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q36.2	2	224845209	NR	DOCK10; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7577271-A; rs16866224-G; rs11675790-C; rs11682884-G; rs10210350-A; rs1821409-T; rs6732013-T; rs6436514-A; rs16866219-C	rs7577271; rs16866224; rs11675790; rs11682884; rs10210350; rs1821409; rs6732013; rs6436514; rs16866219	0	NA	synonymous_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.252	7e-13	12.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.252	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q36.2	2	224845209	NR	DOCK10; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7577271-A; rs16866224-G; rs11675790-C; rs11682884-G; rs10210350-A; rs1821409-C; rs6732013-T; rs6436514-A; rs16866219-C	rs7577271; rs16866224; rs11675790; rs11682884; rs10210350; rs1821409; rs6732013; rs6436514; rs16866219	0	NA	synonymous_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.481	9e-6	5.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.481	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q36.3	2;2	227305484;227270464	NR	MFF-DT; COL4A3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; MFF-DT; COL4A3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12468610-T; rs6436674-T; rs2070735-C; rs6436676-T; rs6436672-G; rs4073904-A; rs9646881-G; rs6436677-C; rs6707977-G; rs11677877-A; rs7606754-G; rs7587228-T; rs4673188-G; rs4619602-T	rs12468610; rs6436674; rs2070735; rs6436676; rs6436672; rs4073904; rs9646881; rs6436677; rs6707977; rs11677877; rs7606754; rs7587228; rs4673188; rs4619602	0	NA	non_coding_transcript_exon_variant; intron_variant; 3_prime_UTR_variant; non_coding_transcript_exon_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; missense_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant	NA	0.0	5e-7	6.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q36.3	2;2	227305484;227270464	NR	MFF-DT; COL4A3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; MFF-DT; COL4A3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12468610-T; rs6436674-T; rs2070735-C; rs6436676-T; rs6436672-G; rs4073904-G; rs9646881-G; rs6436677-C; rs6707977-G; rs11677877-A; rs7606754-G; rs7587228-T; rs4673188-G; rs4619602-T	rs12468610; rs6436674; rs2070735; rs6436676; rs6436672; rs4073904; rs9646881; rs6436677; rs6707977; rs11677877; rs7606754; rs7587228; rs4673188; rs4619602	0	NA	non_coding_transcript_exon_variant; intron_variant; 3_prime_UTR_variant; non_coding_transcript_exon_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; missense_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant	NA	0.135	3e-6	5.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.135	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q37.3	2	238174526	NR	ILKAP; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4663854-T; rs1374387-T; rs11677736-T; rs13020362-G; rs6722284-C; rs7598219-G; rs2880131-A; rs6431588-C; rs4663855-T; rs2278737-A; rs3795904-C; rs6749351-G	rs4663854; rs1374387; rs11677736; rs13020362; rs6722284; rs7598219; rs2880131; rs6431588; rs4663855; rs2278737; rs3795904; rs6749351	0	NA	intron_variant; intron_variant; intron_variant; regulatory_region_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; synonymous_variant; intron_variant; intron_variant	NA	0.001	4e-30	29.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.001	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q37.3	2	238174526	NR	ILKAP; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4663854-T; rs1374387-T; rs11677736-T; rs13020362-G; rs6722284-C; rs7598219-G; rs2880131-A; rs6431588-C; rs4663855-T; rs2278737-A; rs3795904-T; rs6749351-G	rs4663854; rs1374387; rs11677736; rs13020362; rs6722284; rs7598219; rs2880131; rs6431588; rs4663855; rs2278737; rs3795904; rs6749351	0	NA	intron_variant; intron_variant; intron_variant; regulatory_region_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; synonymous_variant; intron_variant; intron_variant	NA	0.335	1e-17	17	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.335	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q37.3	2	239074483	NR	HDAC4; No mapped genes	NA	NA	NA	NA	NA	rs9308908-C; rs2100172-T	rs9308908; rs2100172	0	NA	intron_variant; intron_variant	NA	0.278	2e-13	12.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.278	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q37.3	2	239074483	NR	HDAC4; No mapped genes	NA	NA	NA	NA	NA	rs9308908-T; rs2100172-T	rs9308908; rs2100172	0	NA	intron_variant; intron_variant	NA	0.563	3e-7	6.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.563	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q37.3	2	239757075	NR	No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11897501-C; rs1866136-T; rs4852123-C	rs11897501; rs1866136; rs4852123	0	NA	intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	3e-34	33.52287874528034	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	2q37.3	2	239757075	NR	No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11897501-T; rs1866136-T; rs4852123-C	rs11897501; rs1866136; rs4852123	0	NA	intergenic_variant; intergenic_variant; intergenic_variant	NA	0.409	4e-18	17.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.409	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	20p13	20	159200	NR	DEFB127 - DEFB128; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4142303-A; rs4142304-C; rs6077288-G; rs6055356-C; rs6086092-T; rs2298108-T; rs1858594-C; rs16995685-A; rs6039029-G; rs12624951-G; rs6039035-C; rs11087789-C; rs1434790-G; rs2298109-T; rs6086352-G; rs6038867-T	rs4142303; rs4142304; rs6077288; rs6055356; rs6086092; rs2298108; rs1858594; rs16995685; rs6039029; rs12624951; rs6039035; rs11087789; rs1434790; rs2298109; rs6086352; rs6038867	0	NA	intergenic_variant; 3_prime_UTR_variant; intron_variant; intergenic_variant; intergenic_variant; 5_prime_UTR_variant; intron_variant; missense_variant; intergenic_variant; splice_region_variant; intergenic_variant; intron_variant; intergenic_variant; 5_prime_UTR_variant; intergenic_variant; intergenic_variant	NA	0.0	9e-28	27.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	17q21.31	17	45618793	CRHR1-IT1, CRHR1, RP11-105N13.4	RPS26P8 - LINC02210	ENSG00000282238	ENSG00000204650	NA	9875	1535	rs675600-T	rs675600	0	675600	intergenic_variant	TRUE	0.2045	3e-11	10.522878745280337	NA	0.03035789	[0.021-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.2045	NA	0.03035789
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	17q22	17	58279141	MPO	MPO	NA	NA	ENSG00000005381	NA	NA	rs56378716-G	rs56378716	0	56378716	missense_variant	FALSE	0.0127	2e-18	17.69897000433602	NA	0.1400379	[0.11-0.17] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.0127	NA	0.1400379
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	17q23.1	17	59748211	VMP1	VMP1	NA	NA	ENSG00000062716	NA	NA	rs11654074-C	rs11654074	0	11654074	intron_variant	FALSE	0.5229	1e-17	17	NA	0.03126701	[0.024-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.5229	NA	0.03126701
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	17q25.1	17	74703245	CD300LF, RAB37	RAB37, CD300LF	NA	NA	ENSG00000172794, ENSG00000186074	NA	NA	rs749780-A	rs749780	0	749780	intron_variant	FALSE	0.7317	5e-9	8.301029995663981	NA	0.02374859	[0.016-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.7317	NA	0.02374859
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	18q11.2	18	23571654	NPC1	NPC1	NA	NA	ENSG00000141458	NA	NA	rs147694761-C	rs147694761	1	10618426	intron_variant	FALSE	0.6111	2e-11	10.698970004336019	NA	0.02495232	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.6111	NA	0.02495232
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	18q12.3	18	44533186	CTC-782O7.1	LINC01478	NA	NA	ENSG00000267337	NA	NA	rs16978075-C	rs16978075	0	16978075	intron_variant	FALSE	0.11	1e-10	10	NA	0.0372829	[0.026-0.049] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.11	NA	0.0372829
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	18q21.1	18	46245574	C18orf25	C18orf25	NA	NA	ENSG00000152242	NA	NA	rs398032702-TA	rs398032702	1	5824619	intron_variant	FALSE	0.5442	2e-9	8.698970004336019	NA	0.02180245	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.5442	NA	0.02180245
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	18q21.1	18	50621506	MAPK4	MAPK4	NA	NA	ENSG00000141639	NA	NA	rs1025688-A	rs1025688	0	1025688	intron_variant	FALSE	0.3744	4e-10	9.397940008672037	NA	0.0233293	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.3744	NA	0.0233293
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	19p13.3	19	1049306	ABCA7	ABCA7	NA	NA	ENSG00000064687	NA	NA	rs4147915-A	rs4147915	0	4147915	synonymous_variant	FALSE	0.1475	1e-12	12	NA	0.0368177	[0.027-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.1475	NA	0.0368177
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	NA	NA	NA	S1PR4	NA	NA	NA	NA	NA	NA	chr19:3179884-T	chr19:3179884	0	NA	NA	TRUE	0.0069	6e-43	42.221848749616356	NA	0.316071	[0.27-0.36] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.0069	NA	0.316071
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	19p13.2	19	7777783	intergenic	CLEC4M - CLEC4GP1	ENSG00000104938	ENSG00000268297	NA	8178	9766	rs4804815-G	rs4804815	0	4804815	intergenic_variant	TRUE	0.2766	3e-10	9.522878745280337	NA	0.025186	[0.017-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.2766	NA	0.025186
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	19p13.2	19	10222312	CTD-2369P2.2	S1PR2, DNMT1	NA	NA	ENSG00000267534, ENSG00000130816	NA	NA	rs10409243-T	rs10409243	0	10409243	3_prime_UTR_variant	FALSE	0.6028	4e-9	8.397940008672037	NA	0.02207318	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.6028	NA	0.02207318
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	19p13.11	19	18405498	AC008397.1	LRRC25 - SSBP4	ENSG00000175489	ENSG00000130511	NA	7876	13366	rs575404063-C	rs575404063	1	35960487	intergenic_variant	TRUE	0.4872	2e-13	12.698970004336019	NA	0.02677423	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.4872	NA	0.02677423
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	19q13.31	19	43648948	PLAUR	PLAUR	NA	NA	ENSG00000011422	NA	NA	rs4760-G	rs4760	0	4760	missense_variant	FALSE	0.1569	1e-68	68	NA	0.08614908	[0.077-0.096] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.1569	NA	0.08614908
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	19q13.32	19	45241584	MARK4, AC006126.4	EXOC3L2, MARK4	NA	NA	ENSG00000283632, ENSG00000007047	NA	NA	rs73036517-G	rs73036517	0	73036517	intron_variant	FALSE	0.2596	4e-32	31.397940008672037	NA	0.04852503	[0.04-0.057] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.2596	NA	0.04852503
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	19q13.33	19	48640989	SEC1P, CA11	CA11, SEC1P	NA	NA	ENSG00000063180, ENSG00000232871	NA	NA	rs11428934-TG	rs11428934	0	11428934	intron_variant	FALSE	0.7585	6e-13	12.221848749616356	NA	0.03038777	[0.022-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.7585	NA	0.03038777
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	19q13.41	19	51376740	NKG7	NKG7 - LIM2	ENSG00000105374	ENSG00000105370	NA	4039	3169	rs34733715-A	rs34733715	0	34733715	intergenic_variant	TRUE	0.2624	7e-9	8.154901959985743	NA	0.02374675	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.2624	NA	0.02374675
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	20q13.12	20	44413724	HNF4A	HNF4A	NA	NA	ENSG00000101076	NA	NA	rs1800961-T	rs1800961	0	1800961	missense_variant	FALSE	0.0314	6e-12	11.221848749616356	NA	0.07093605	[0.051-0.091] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.0314	NA	0.07093605
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	21q22.2	21	39091357	intergenic	NA - RPL23AP12	NA	ENSG00000228861	NA	NA	36211	rs9977672-A	rs9977672	0	9977672	intergenic_variant	TRUE	0.2583	7e-10	9.154901959985743	NA	0.02553876	[0.017-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.2583	NA	0.02553876
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	22q11.21	22	17688884	BCL2L13	BCL2L13	NA	NA	ENSG00000099968	NA	NA	rs5013026-T	rs5013026	0	5013026	intron_variant	FALSE	0.5045	8e-9	8.096910013008056	NA	0.02062524	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.5045	NA	0.02062524
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil count	170,702 European ancestry individuals	NA	22q12.2	22	31417072	DRG1	DRG1	NA	NA	ENSG00000185721	NA	NA	rs35955747-T	rs35955747	0	35955747	intron_variant	FALSE	0.5393	8e-9	8.096910013008056	NA	0.02074905	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count	http://www.ebi.ac.uk/efo/EFO_0004833	GCST004629	Genome-wide genotyping array	0.5393	NA	0.02074905
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	1p36.32	1	3080038	PRDM16	PRDM16	NA	NA	ENSG00000142611	NA	NA	rs1569419-C	rs1569419	0	1569419	intron_variant	FALSE	0.7652	4e-14	13.397940008672037	NA	0.03186936	[0.024-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.7652	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	1p36.22	1	11821084	CLCN6	CLCN6	NA	NA	ENSG00000011021	NA	NA	rs545709142-A	rs545709142	0	545709142	intron_variant	FALSE	0.162	2e-11	10.698970004336019	NA	0.03218788	[0.023-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.162	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	1p36.12	1	23514124	E2F2	E2F2, E2F2	NA	NA	ENSG00000282899, ENSG00000007968	NA	NA	rs35229050-T	rs35229050	0	35229050	intron_variant	FALSE	0.5455	7e-13	12.154901959985743	NA	0.02572019	[0.019-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.5455	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	1p34.3	1	37473572	LINC01137	LINC01137	NA	NA	ENSG00000233621	NA	NA	rs2492301-C	rs2492301	0	2492301	intron_variant	FALSE	0.5296	9e-13	12.045757490560675	NA	0.02542396	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.5296	NA	NA
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	15q14	15	38042063	TMCO5A	LINC02345	NA	NA	ENSG00000259225	NA	NA	rs7176106-A	rs7176106	0	7176106	intron_variant	FALSE	0.474052	2e-8	7.698970004336019	NA	0.0489	[0.032-0.066] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.474052	NA	0.0489
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	15q22.33	15	67134851	SMAD3	SMAD3	NA	NA	ENSG00000166949	NA	NA	rs11631380-T	rs11631380	0	11631380	intron_variant	FALSE	0.311342	2e-8	7.698970004336019	NA	0.0409	[0.027-0.055] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.311342	NA	0.0409
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	2p21	2	42027216	PKDCC	C2orf91 - PKDCC	ENSG00000205086	ENSG00000162878	NA	70410	20805	rs2165239-T	rs2165239	0	2165239	regulatory_region_variant	TRUE	0.230635	6e-9	8.221848749616356	NA	0.0475	[0.031-0.064] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.230635	NA	0.0475
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	2q14.2	2	118772253	EN1	LINC01956	NA	NA	ENSG00000258910	NA	NA	rs55983207-T	rs55983207	0	55983207	intron_variant	FALSE	0.951918	3e-9	8.522878745280337	NA	0.107	[0.072-0.142] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.951918	NA	0.107
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	2q24.3	2	165709495	CSRNP3	CSRNP3 - GALNT3	ENSG00000178662	ENSG00000115339	NA	20088	38093	rs34095745-A	rs34095745	0	34095745	intergenic_variant	TRUE	0.499915	6e-16	15.221848749616356	NA	0.0556	[0.042-0.069] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.499915	NA	0.0556
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	3p22.1	3	41104864	CTNNB1	NA - MRPS31P1	NA	ENSG00000275256	NA	NA	84177	rs2024219-T	rs2024219	0	2024219	intergenic_variant	TRUE	0.488576	1e-16	16	NA	0.0574	[0.044-0.071] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.488576	NA	0.0574
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	16q24.1	16	86681109	FOXL1	FOXL1 - LINC02188	ENSG00000176678	ENSG00000261175	NA	97631	29013	rs71390846-C	rs71390846	0	71390846	intergenic_variant	TRUE	0.188269	2e-11	10.698970004336019	NA	0.0595	[0.042-0.077] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.188269	NA	0.0595
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	4q22.1	4	87910097	HSP90AB3P	HSP90AB3P - SPP1	ENSG00000183199	ENSG00000118785	NA	16082	65570	rs11934731-A	rs11934731	0	11934731	intergenic_variant	TRUE	0.484937	2e-7	6.698970004336019	NA	0.0379	[0.024-0.052] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.484937	NA	0.0379
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	17q21.31	17	43749471	SOST	WHSC1L2P - SOST	ENSG00000267253	ENSG00000167941	NA	29035	4267	rs2741856-C	rs2741856	0	2741856	intergenic_variant	TRUE	0.080564	3e-11	10.522878745280337	NA	0.0895	[0.063-0.116] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.080564	NA	0.0895
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	18q21.33	18	62387624	TNFRSF11A	TNFRSF11A	NA	NA	ENSG00000141655	NA	NA	rs884205-A	rs884205	0	884205	3_prime_UTR_variant	FALSE	0.523571	6e-10	9.221848749616356	NA	0.0501	[0.034-0.066] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.523571	NA	0.0501
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	6q25.1	6	151575100	C6ORF97	CCDC170	NA	NA	ENSG00000120262	NA	NA	rs9479075-A	rs9479075	0	9479075	intron_variant	FALSE	0.488202	2e-13	12.698970004336019	NA	0.0515	[0.038-0.065] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.488202	NA	0.0515
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	7q21.3	7	96525600	FLJ42280	SEM1	NA	NA	ENSG00000127922	NA	NA	rs4448201-C	rs4448201	0	4448201	intron_variant	FALSE	0.476959	3e-20	19.522878745280337	NA	0.0668	[0.052-0.081] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.476959	NA	0.0668
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	20p12.1	20	14643952	MACROD2	MACROD2	NA	NA	ENSG00000172264	NA	NA	rs73100693-A	rs73100693	0	73100693	intron_variant	FALSE	0.222008	3e-8	7.522878745280337	NA	0.0495	[0.032-0.067] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.222008	NA	0.0495
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	20q13.33	20	62251748	OSBPL2	OSBPL2	NA	NA	ENSG00000130703	NA	NA	rs6143006-T	rs6143006	0	6143006	intron_variant	FALSE	0.542231	8e-6	5.096910013008056	NA	0.0305	[0.017-0.044] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.542231	NA	0.0305
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	9q34.12	9	130606176	FUBP3	FUBP3	NA	NA	ENSG00000107164	NA	NA	rs9657746-C	rs9657746	0	9657746	intron_variant	FALSE	0.647884	2e-8	7.698970004336019	NA	0.0407	[0.027-0.055] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.647884	NA	0.0407
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	10q21.1	10	52663112	MBL2	LNCAROD	NA	NA	ENSG00000231131	NA	NA	rs12256387-A	rs12256387	0	12256387	intron_variant	FALSE	0.100235	1e-6	6	NA	0.0529	[0.032-0.074] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.100235	NA	0.0529
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	10q26.13	10	122427198	PLEKHA1	PLEKHA1	NA	NA	ENSG00000107679	NA	NA	rs2292626-T	rs2292626	0	2292626	intron_variant	FALSE	0.479602	2e-8	7.698970004336019	NA	0.0386	[0.025-0.052] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.479602	NA	0.0386
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	11p15.2	11	15647280	SOX6	LINC02751 - LINC02725	ENSG00000254946	ENSG00000273415	NA	43111	112448478	rs1531903-C	rs1531903	0	1531903	intron_variant	TRUE	0.548456	3e-20	19.522878745280337	NA	0.0824	[0.065-0.1] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.548456	NA	0.0824
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	2p13.3	2	68735005	ARHGAP25	ARHGAP25	NA	NA	ENSG00000163219	NA	NA	rs10048745-A	rs10048745	0	10048745	5_prime_UTR_variant	FALSE	0.26	4e-8	7.3979400086720375	NA	0.0503	[0.032-0.068] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.26	NA	0.0503
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	11q13.2	11	68425050	LRP5	LRP5	NA	NA	ENSG00000162337	NA	NA	rs554734-T	rs554734	0	554734	intron_variant	FALSE	0.69	4e-7	6.3979400086720375	NA	0.037	[0.023-0.051] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.69	NA	0.037
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	12q13.13	12	53277765	ESPL1	ESPL1	NA	NA	ENSG00000135476	NA	NA	rs2272313-A	rs2272313	0	2272313	intron_variant	FALSE	0.519258	2e-6	5.698970004336019	NA	0.0337	[0.02-0.048] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.519258	NA	0.0337
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	14q32.11	14	90986497	RPS6KA5	RPS6KA5	NA	NA	ENSG00000100784	NA	NA	rs1286063-T	rs1286063	0	1286063	intron_variant	FALSE	0.802686	4e-8	7.3979400086720375	NA	0.0468	[0.03-0.064] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.802686	NA	0.0468
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	4q22.1	4	87910097	HSP90AB3P	HSP90AB3P - SPP1	ENSG00000183199	ENSG00000118785	NA	16082	65570	rs11934731-A	rs11934731	0	11934731	intergenic_variant	TRUE	0.484937	7e-11	10.154901959985743	NA	0.0536	[0.038-0.07] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.484937	NA	0.0536
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	6p22.3	6	21391051	CDKAL1	NA - LINC00581	NA	ENSG00000280989	NA	NA	94845	rs10946458-T	rs10946458	0	10946458	intergenic_variant	TRUE	0.667062	2e-9	8.698970004336019	NA	0.05	[0.034-0.066] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.667062	NA	0.05
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	6q25.1	6	151575100	C6ORF97	CCDC170	NA	NA	ENSG00000120262	NA	NA	rs9479075-A	rs9479075	0	9479075	intron_variant	FALSE	0.488202	4e-14	13.397940008672037	NA	0.06	[0.045-0.075] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.488202	NA	0.06
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	7p14.1	7	38058260	EPDR1	SFRP4 - NA	ENSG00000106483	NA	NA	32565	NA	rs1357651-T	rs1357651	0	1357651	intergenic_variant	TRUE	0.53436	6e-15	14.221848749616356	NA	0.063	[0.047-0.079] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.53436	NA	0.063
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	7q21.3	7	96525600	FLJ42280	SEM1	NA	NA	ENSG00000127922	NA	NA	rs4448201-C	rs4448201	0	4448201	intron_variant	FALSE	0.476959	1e-11	11	NA	0.0563	[0.04-0.073] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.476959	NA	0.0563
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	7q22.1	7	99533211	ZKSCAN5	ZKSCAN5	NA	NA	ENSG00000196652	NA	NA	rs34670419-T	rs34670419	0	34670419	3_prime_UTR_variant	FALSE	0.03883	1e-8	8	NA	0.1218	[0.08-0.164] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.03883	NA	0.1218
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	7q31.31	7	121326736	WNT16	WNT16	NA	NA	ENSG00000002745	NA	NA	rs3779381-A	rs3779381	0	3779381	intron_variant	FALSE	0.742765	1e-18	18	NA	0.0782	[0.061-0.096] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.742765	NA	0.0782
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	8q24.12	8	119000622	TNFRSF11B	COLEC10	NA	NA	ENSG00000184374	NA	NA	rs13264172-A	rs13264172	0	13264172	intron_variant	FALSE	0.50513	3e-25	24.522878745280337	NA	0.0812	[0.066-0.096] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.50513	NA	0.0812
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	1p36.12	1	22371954	ZBTB40	PPIAP34 - ZBTB40	ENSG00000234397	ENSG00000184677	NA	48623	56884	rs7524102-A	rs7524102	0	7524102	intergenic_variant	TRUE	0.830289	1e-20	20	NA	0.0828	[0.065-0.1] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.830289	NA	0.0828
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	1p31.3	1	68191014	WLS	GNG12-AS1, WLS	NA	NA	ENSG00000232284, ENSG00000116729	NA	NA	rs2566752-T	rs2566752	0	2566752	intron_variant	FALSE	0.623326	5e-20	19.30102999566398	NA	0.0644	[0.051-0.078] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.623326	NA	0.0644
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	16p13.3	16	331141	AXIN1	AXIN1	NA	NA	ENSG00000103126	NA	NA	rs12719801-T	rs12719801	0	12719801	intron_variant	FALSE	0.356265	1e-9	9	NA	0.044	[0.03-0.058] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.356265	NA	0.044
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	16q12.1	16	50952397	CYLD	LINC02128 - LINC02127	ENSG00000261241	ENSG00000261637	NA	51334	65147	rs1564981-A	rs1564981	0	1564981	intergenic_variant	TRUE	0.455413	4e-7	6.3979400086720375	NA	0.0347	[0.021-0.048] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.455413	NA	0.0347
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	4p16.3	4	1016289	FGFRL1	FGFRL1	NA	NA	ENSG00000127418	NA	NA	rs35654957-T	rs35654957	0	35654957	intron_variant	FALSE	0.632266	4e-10	9.397940008672037	NA	0.0478	[0.033-0.063] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.632266	NA	0.0478
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	17p13.3	17	2145419	SMG6	SMG6	NA	NA	ENSG00000070366	NA	NA	rs7209460-T	rs7209460	0	7209460	intron_variant	FALSE	0.485208	2e-12	11.698970004336019	NA	0.0529	[0.038-0.068] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.485208	NA	0.0529
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	5q14.3	5	89062462	MEF2C	MEF2C-AS1	NA	NA	ENSG00000248309	NA	NA	rs7727117-A	rs7727117	0	7727117	intron_variant	FALSE	0.368207	1e-21	21	NA	0.0675	[0.054-0.081] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.368207	NA	0.0675
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	6p22.3	6	21391051	CDKAL1	NA - LINC00581	NA	ENSG00000280989	NA	NA	94845	rs10946458-T	rs10946458	0	10946458	intergenic_variant	TRUE	0.667062	2e-10	9.698970004336019	NA	0.0463	[0.032-0.061] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.667062	NA	0.0463
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	6q22.33	6	126823538	RSPO3	NA	NA	NA	NA	NA	NA	rs13194508-T	rs13194508	0	13194508	intron_variant	TRUE	0.751557	2e-10	9.698970004336019	NA	0.0528	[0.037-0.069] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.751557	NA	0.0528
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	19q13.11	19	33066506	RHPN2	RHPN2 - GPATCH1	ENSG00000131941	ENSG00000076650	NA	1618	14393	rs8106453-T	rs8106453	0	8106453	intergenic_variant	TRUE	0.254589	3e-8	7.522878745280337	NA	0.0476	[0.031-0.064] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.254589	NA	0.0476
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	7q22.1	7	99533211	ZKSCAN5	ZKSCAN5	NA	NA	ENSG00000196652	NA	NA	rs34670419-T	rs34670419	0	34670419	3_prime_UTR_variant	FALSE	0.03883	8e-6	5.096910013008056	NA	0.0839	[0.047-0.121] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.03883	NA	0.0839
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	7q31.31	7	121326736	WNT16	WNT16	NA	NA	ENSG00000002745	NA	NA	rs3779381-A	rs3779381	0	3779381	intron_variant	FALSE	0.742765	1e-14	14	NA	0.0605	[0.045-0.076] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.742765	NA	0.0605
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	8q24.12	8	119000622	TNFRSF11B	COLEC10	NA	NA	ENSG00000184374	NA	NA	rs13264172-A	rs13264172	0	13264172	intron_variant	FALSE	0.50513	1e-16	16	NA	0.0571	[0.044-0.071] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.50513	NA	0.0571
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	1p36.12	1	22371954	ZBTB40	PPIAP34 - ZBTB40	ENSG00000234397	ENSG00000184677	NA	48623	56884	rs7524102-A	rs7524102	0	7524102	intergenic_variant	TRUE	0.830289	5e-18	17.30102999566398	NA	0.087	[0.067-0.107] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.830289	NA	0.087
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	1p31.3	1	68191014	WLS	GNG12-AS1, WLS	NA	NA	ENSG00000232284, ENSG00000116729	NA	NA	rs2566752-T	rs2566752	0	2566752	intron_variant	FALSE	0.623326	4e-23	22.397940008672037	NA	0.0789	[0.063-0.095] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.623326	NA	0.0789
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	2p16.2	2	54457420	SPTBN1	SPTBN1	NA	NA	ENSG00000115306	NA	NA	rs11898505-A	rs11898505	0	11898505	intron_variant	FALSE	0.51501	3e-9	8.522878745280337	NA	0.0491	[0.033-0.065] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.51501	NA	0.0491
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	11p15.2	11	16735326	C11ORF58	SOX6, C11orf58	NA	NA	ENSG00000110693, ENSG00000110696	NA	NA	rs11024028-C	rs11024028	0	11024028	intron_variant	FALSE	0.807246	3e-10	9.522878745280337	NA	0.0574	[0.04-0.075] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.807246	NA	0.0574
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Femoral neck bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	11p11.2	11	46702387	ZNF408	ZNF408	NA	NA	ENSG00000175213	NA	NA	rs12361673-A	rs12361673	0	12361673	intron_variant	FALSE	0.475188	5e-9	8.301029995663981	NA	0.0446	[0.03-0.059] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	femoral neck bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007785	GCST005795	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.475188	NA	0.0446
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	2q24.3	2	165709495	CSRNP3	CSRNP3 - GALNT3	ENSG00000178662	ENSG00000115339	NA	20088	38093	rs34095745-A	rs34095745	0	34095745	intergenic_variant	TRUE	0.499915	2e-11	10.698970004336019	NA	0.0521	[0.037-0.067] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.499915	NA	0.0521
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	3p22.1	3	41104864	CTNNB1	NA - MRPS31P1	NA	ENSG00000275256	NA	NA	84177	rs2024219-T	rs2024219	0	2024219	intergenic_variant	TRUE	0.488576	3e-12	11.522878745280337	NA	0.055	[0.04-0.07] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.488576	NA	0.055
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	10p12.1	10	28189563	MPP7	MPP7	NA	NA	ENSG00000150054	NA	NA	rs11006914-T	rs11006914	0	11006914	intron_variant	FALSE	0.195525	1e-9	9	NA	0.0575	[0.039-0.076] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.195525	NA	0.0575
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	10q21.1	10	52663112	MBL2	LNCAROD	NA	NA	ENSG00000231131	NA	NA	rs12256387-A	rs12256387	0	12256387	intron_variant	FALSE	0.100235	2e-8	7.698970004336019	NA	0.0684	[0.044-0.092] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.100235	NA	0.0684
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	10q22.3	10	77641558	KCNMA1	KCNMA1 - NA	ENSG00000156113	NA	NA	3189	NA	rs7071206-T	rs7071206	0	7071206	intergenic_variant	TRUE	0.790543	5e-9	8.301029995663981	NA	0.0543	[0.036-0.073] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.790543	NA	0.0543
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	11p15.2	11	16735326	C11ORF58	SOX6, C11orf58	NA	NA	ENSG00000110693, ENSG00000110696	NA	NA	rs11024028-C	rs11024028	0	11024028	intron_variant	FALSE	0.807246	6e-10	9.221848749616356	NA	0.0648	[0.044-0.085] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.807246	NA	0.0648
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	11q13.2	11	68425050	LRP5	LRP5	NA	NA	ENSG00000162337	NA	NA	rs554734-T	rs554734	0	554734	intron_variant	FALSE	0.69	3e-17	16.522878745280337	NA	0.0695	[0.053-0.086] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.69	NA	0.0695
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	11q14.2	11	87159469	TMEM135	TMEM135	NA	NA	ENSG00000166575	NA	NA	rs664398-T	rs664398	0	664398	intron_variant	FALSE	0.689194	2e-8	7.698970004336019	NA	0.0464	[0.03-0.062] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.689194	NA	0.0464
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	12q13.13	12	53277765	ESPL1	ESPL1	NA	NA	ENSG00000135476	NA	NA	rs2272313-A	rs2272313	0	2272313	intron_variant	FALSE	0.519258	3e-13	12.522878745280337	NA	0.0583	[0.043-0.074] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.519258	NA	0.0583
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	12q21.33	12	89906201	LOC338758	NA - BRWD1P2	NA	ENSG00000258290	NA	NA	13236	rs4573745-A	rs4573745	0	4573745	intron_variant	TRUE	0.544462	2e-8	7.698970004336019	NA	0.0589	[0.038-0.079] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.544462	NA	0.0589
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	13q14.11	13	42390067	AKAP11	LINC02341	NA	NA	ENSG00000283554	NA	NA	rs17457561-A	rs17457561	0	17457561	intron_variant	FALSE	0.239937	6e-18	17.221848749616356	NA	0.0792	[0.061-0.097] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.239937	NA	0.0792
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	14q32.11	14	90986497	RPS6KA5	RPS6KA5	NA	NA	ENSG00000100784	NA	NA	rs1286063-T	rs1286063	0	1286063	intron_variant	FALSE	0.802686	6e-12	11.221848749616356	NA	0.066	[0.047-0.085] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.802686	NA	0.066
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	15q14	15	38042063	TMCO5A	LINC02345	NA	NA	ENSG00000259225	NA	NA	rs7176106-A	rs7176106	0	7176106	intron_variant	FALSE	0.474052	3e-7	6.522878745280337	NA	0.0502	[0.031-0.069] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.474052	NA	0.0502
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	15q22.33	15	67134851	SMAD3	SMAD3	NA	NA	ENSG00000166949	NA	NA	rs11631380-T	rs11631380	0	11631380	intron_variant	FALSE	0.311342	1e-6	6	NA	0.0403	[0.024-0.056] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.311342	NA	0.0403
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	16p13.3	16	331141	AXIN1	AXIN1	NA	NA	ENSG00000103126	NA	NA	rs12719801-T	rs12719801	0	12719801	intron_variant	FALSE	0.356265	6e-9	8.221848749616356	NA	0.048	[0.032-0.064] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.356265	NA	0.048
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	16q12.1	16	50952397	CYLD	LINC02128 - LINC02127	ENSG00000261241	ENSG00000261637	NA	51334	65147	rs1564981-A	rs1564981	0	1564981	intergenic_variant	TRUE	0.455413	8e-9	8.096910013008056	NA	0.0447	[0.03-0.06] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.455413	NA	0.0447
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	16q24.1	16	86681109	FOXL1	FOXL1 - LINC02188	ENSG00000176678	ENSG00000261175	NA	97631	29013	rs71390846-C	rs71390846	0	71390846	intergenic_variant	TRUE	0.188269	1e-9	9	NA	0.0613	[0.042-0.081] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.188269	NA	0.0613
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	17q21.31	17	43749471	SOST	WHSC1L2P - SOST	ENSG00000267253	ENSG00000167941	NA	29035	4267	rs2741856-C	rs2741856	0	2741856	intergenic_variant	TRUE	0.080564	5e-9	8.301029995663981	NA	0.0898	[0.06-0.12] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.080564	NA	0.0898
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	18q21.33	18	62387624	TNFRSF11A	TNFRSF11A	NA	NA	ENSG00000141655	NA	NA	rs884205-A	rs884205	0	884205	3_prime_UTR_variant	FALSE	0.523571	2e-12	11.698970004336019	NA	0.0643	[0.046-0.082] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.523571	NA	0.0643
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	19q13.11	19	33066506	RHPN2	RHPN2 - GPATCH1	ENSG00000131941	ENSG00000076650	NA	1618	14393	rs8106453-T	rs8106453	0	8106453	intergenic_variant	TRUE	0.254589	3e-11	10.522878745280337	NA	0.0662	[0.047-0.086] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.254589	NA	0.0662
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	20p12.2	20	10679415	JAG1	JAG1 - LINC01752	ENSG00000101384	ENSG00000224961	NA	5416	17534	rs6040079-T	rs6040079	0	6040079	intron_variant	TRUE	0.388241	6e-9	8.221848749616356	NA	0.0479	[0.032-0.064] unit decrease	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.388241	NA	0.0479
2018-07-04	29499414	Pei YF	2018-02-27	Bone	www.ncbi.nlm.nih.gov/pubmed/29499414	Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.	Lumbar spine bone mineral density	up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals	NA	20q13.33	20	62251748	OSBPL2	OSBPL2	NA	NA	ENSG00000130703	NA	NA	rs6143006-T	rs6143006	0	6143006	intron_variant	FALSE	0.542231	2e-8	7.698970004336019	NA	0.0434	[0.028-0.059] unit increase	Affymetrix, Illumina [7998108] (imputed)	N	spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007701	GCST005796	Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing	0.542231	NA	0.0434
2017-06-29	28360221	Boger CA	2017-03-30	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/28360221	NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.	Blood osmolality (transformed sodium)	45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals	17,637 European ancestry individuals	7p12.1	7	52917714	NR	SGO1P2 - NA	ENSG00000234304	NA	NA	19907	NA	rs3923547-A	rs3923547	0	3923547	regulatory_region_variant	TRUE	0.06	9e-6	5.045757490560675	(Asian)	0.2	[0.11-0.29] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	blood osmolality measurement	http://www.ebi.ac.uk/efo/EFO_0007967	GCST004267	Genome-wide genotyping array	0.06	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.1	7	28144083	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs849140-T	rs849140	0	849140	intron_variant	FALSE	0.4097	6e-13	12.221848749616356	NA	0.0256	[0.019-0.033] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.4097	NA	0.0256
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	8q13.3	8	71557507	LOC100132809	EYA1	NA	NA	ENSG00000104313	NA	NA	rs4738141-G	rs4738141	0	4738141	intron_variant	FALSE	0.27290000000000003	2e-8	7.698970004336019	NA	0.0234	[0.015-0.032] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.27290000000000003	NA	0.0234
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9q22.32	9	95648123	PTCH1	NA	NA	NA	NA	NA	NA	rs10990303-T	rs10990303	0	10990303	intergenic_variant	TRUE	0.2283	3e-10	9.522878745280337	NA	0.0271	[0.019-0.036] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2283	NA	0.0271
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9q31.2	9	106156346	TMEM38B	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs7032974-T	rs7032974	0	7032974	intron_variant	FALSE	0.7188	2e-7	6.698970004336019	NA	0.0228	[0.014-0.031] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7188	NA	0.0228
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Systolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	8p23.1	8	11594668	BLK, GATA4	LINC00208 - GATA4	ENSG00000170983	ENSG00000285109	NA	11851	82291	rs4841569-?	rs4841569	0	4841569	regulatory_region_variant	TRUE	NR	6e-18	17.221848749616356	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335	GCST006188	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Systolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	10p12.31	10	18418519	CACNB2	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs1813353-?	rs1813353	0	1813353	intron_variant	FALSE	NR	3e-30	29.522878745280337	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335	GCST006188	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Systolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	10q21.2	10	61707795	C10orf107	CABCOCO1	NA	NA	ENSG00000183346	NA	NA	rs4590817-?	rs4590817	0	4590817	intron_variant	FALSE	NR	1e-18	18	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335	GCST006188	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12p12.1	12	26290097	ITPR2, SSPN	SSPN	NA	NA	ENSG00000123096	NA	NA	rs4963975-A	rs4963975	0	4963975	intron_variant	FALSE	0.2535	4e-9	8.397940008672037	NA	0.0241	[0.016-0.032] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2535	NA	0.0241
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Systolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	10q24.32	10	103086421	CYP17A1, NT5C2, CNNM2-AS3MT	CNNM2	NA	NA	ENSG00000148842	NA	NA	rs11191548-?	rs11191548	0	11191548	3_prime_UTR_variant	FALSE	NR	1e-45	45	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335	GCST006188	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q13.13	12	54027692	HOXC4, HOXC5, HOXC6	HOXC4, HOXC6	NA	NA	ENSG00000198353, ENSG00000197757	NA	NA	rs10876528-A	rs10876528	0	10876528	intron_variant	FALSE	0.3539	5e-13	12.301029995663981	NA	0.0292	[0.021-0.037] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3539	NA	0.0292
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Systolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	10q25.3	10	114045297	ADRB1	ADRB1	NA	NA	ENSG00000043591	NA	NA	rs1801253-?	rs1801253	0	1801253	missense_variant	FALSE	NR	1e-22	22	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335	GCST006188	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q23	15	70072013	TLE3	TLE3	NA	NA	ENSG00000140332	NA	NA	rs975210-A	rs975210	0	975210	intron_variant	FALSE	0.1811	3e-8	7.522878745280337	NA	0.0265	[0.017-0.036] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.1811	NA	0.0265
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Systolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	11p15.5	11	1995678	H19	H19	NA	NA	ENSG00000130600	NA	NA	rs217727-?	rs217727	0	217727	non_coding_transcript_exon_variant	FALSE	NR	7e-15	14.154901959985743	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335	GCST006188	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	83913372	ADAMTSL3	ADAMTSL3	NA	NA	ENSG00000156218	NA	NA	rs4842838-T	rs4842838	0	4842838	missense_variant	FALSE	0.5348	6e-27	26.221848749616356	NA	0.0377	[0.031-0.045] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5348	NA	0.0377
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	84597563	ZSCAN2	LINC00933 - ZSCAN2	ENSG00000259728	ENSG00000176371	NA	17388	3423	rs7176527-C	rs7176527	0	7176527	intergenic_variant	TRUE	0.8083	2e-8	7.698970004336019	NA	0.03	[0.019-0.041] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.8083	NA	0.03
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q26.1	15	88872016	ACAN	ACAN	NA	NA	ENSG00000157766	NA	NA	rs3817428-C	rs3817428	0	3817428	missense_variant	FALSE	0.7327	2e-8	7.698970004336019	NA	0.0266	[0.017-0.036] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7327	NA	0.0266
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	16q22.1	16	67357715	LRRC36	LRRC36	NA	NA	ENSG00000159708	NA	NA	rs8055190-C	rs8055190	0	8055190	intron_variant	FALSE	0.8731	4e-9	8.397940008672037	NA	0.0529	[0.035-0.071] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.8731	NA	0.0529
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17p13.3	17	560603	VPS53	VPS53, VPS53	NA	NA	ENSG00000141252, ENSG00000283883	NA	NA	rs741677-A	rs741677	0	741677	intron_variant	FALSE	0.5689	3e-9	8.522878745280337	NA	0.0241	[0.016-0.032] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5689	NA	0.0241
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	1p36.22	1	11802721	MTHFR, NPPB, CLCN6	MTHFR	NA	NA	ENSG00000177000	NA	NA	rs17367504-?	rs17367504	0	17367504	intron_variant	FALSE	NA	9e-40	39.045757490560675	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	1p36.22	1	11845917	MTHFR, NPPB, CLCN6	CLCN6, NPPA	NA	NA	ENSG00000011021, ENSG00000175206	NA	NA	rs5068-?	rs5068	0	5068	3_prime_UTR_variant	FALSE	NA	2e-29	28.69897000433602	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	1q32.1	1	204549714	MDM4	MDM4	NA	NA	ENSG00000198625	NA	NA	rs4245739-?	rs4245739	0	4245739	3_prime_UTR_variant	FALSE	NA	2e-9	8.698970004336019	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p36.13	1	16981663	MFAP2	MFAP2 - ATP13A2	ENSG00000117122	ENSG00000159363	NA	1031	4295	rs9435732-C	rs9435732	0	9435732	intron_variant	TRUE	0.7313000000000001	4e-10	9.397940008672037	(EA, men)	0.039	[0.027-0.051] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7313000000000001	NA	0.039
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118321979	SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126	NA	57490	292354	rs7536458-T	rs7536458	0	7536458	intergenic_variant	TRUE	0.7428	5e-10	9.301029995663981	(EA, men)	0.0401	[0.027-0.053] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7428	NA	0.0401
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	118962811	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs10923712-A	rs10923712	0	10923712	intron_variant	FALSE	0.6229	1e-12	12	(EA, men)	0.0406	[0.029-0.052] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6229	NA	0.0406
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	8p23.1	8	8525195	PRAG1, MFHAS1	PRAG1 - RN7SL178P	ENSG00000275342	ENSG00000284857	NA	138756	57157	rs7823056-?	rs7823056	0	7823056	intergenic_variant	TRUE	NR	4e-11	10.397940008672037	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	8p23.1	8	9293541	PPP1R3B, TNKS	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	5963	77549	rs62493780-?	rs62493780	0	62493780	intron_variant	TRUE	NR	4e-9	8.397940008672037	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	8p23.1	8	9946202	MIR124-1, MSRA	MIR124-1HG - NA	ENSG00000253230	NA	NA	39524	NA	rs13271489-?	rs13271489	0	13271489	intergenic_variant	TRUE	NR	1e-12	12	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	11p15.5	11	1899025	TNNI2, LSP1, TNNT3	LINC01150	NA	NA	ENSG00000229671	NA	NA	rs7483477-?	rs7483477	0	7483477	intron_variant	FALSE	NR	5e-11	10.301029995663981	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	12q21.33	12	89571272	POC1B, ATP2B1	POC1B-AS1 - ATP2B1	ENSG00000270344	ENSG00000070961	NA	23267	16777	rs7313874-?	rs7313874	0	7313874	intron_variant	TRUE	NR	3e-39	38.52287874528034	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	12q21.33	12	89643729	ATP2B1	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs111337717-?	rs111337717	0	111337717	intron_variant	FALSE	NR	3e-19	18.522878745280337	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	12q24.13	12	112569798	PTPN11	PTPN11 - RPH3A	ENSG00000179295	ENSG00000089169	NA	59880	582	rs7974266-?	rs7974266	0	7974266	intergenic_variant	TRUE	NR	4e-14	13.397940008672037	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	17p13.1	17	7877701	NAA38, KCNAB3, VAMP2	NAA38	NA	NA	ENSG00000183011	NA	NA	rs74439044-?	rs74439044	0	74439044	intron_variant	FALSE	NR	2e-21	20.69897000433602	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	4q31.21	4	143133400	INPP4B, GAB1	NA - USP38	NA	ENSG00000170185	NA	NA	51517	rs78763922-?	rs78763922	0	78763922	intron_variant	TRUE	NR	4e-11	10.397940008672037	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	6p21.33	6	31895656	SLC44A4, EHMT2, STK19, CYP21A2, TNXB	EHMT2, EHMT2, EHMT2, EHMT2, EHMT2	NA	NA	ENSG00000236759, ENSG00000206376, ENSG00000232045, ENSG00000227333, ENSG00000204371	NA	NA	rs2243873-?	rs2243873	0	2243873	non_coding_transcript_exon_variant	FALSE	NR	1e-10	10	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	6p21.32	6	32763163	SLC44A4, EHMT2, HLA-DQB2, STK19, CYP21A2, TNXB	HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2	NA	NA	ENSG00000232629, ENSG00000224305, ENSG00000228813, ENSG00000196610, ENSG00000229493, ENSG00000228254, ENSG00000226165	NA	NA	rs2071550-?	rs2071550	0	2071550	intron_variant	FALSE	NR	1e-9	9	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	7p15.2	7	27203602	HOTTIP	HOTTIP	NA	NA	ENSG00000243766	NA	NA	rs2023843-?	rs2023843	0	2023843	intron_variant	FALSE	NR	2e-7	6.698970004336019	(African)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	1p21.3	1	95823780	LOC101928219	LINC02607 - NA	ENSG00000228971	NA	NA	41438	NA	rs182662555-?	rs182662555	0	182662555	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	(African)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	3q21.3	3	127595345	TPRA1, MCM2	TPRA1	NA	NA	ENSG00000163870	NA	NA	rs139963642-?	rs139963642	0	139963642	intron_variant	FALSE	NR	2e-8	7.698970004336019	(African)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	4p15.1	4	30084482	PCDH7	NA	NA	NA	NA	NA	NA	rs11931572-?	rs11931572	0	11931572	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	(African)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	9p22.2	9	18189780	ADAMTSL1, MIR3152	ADAMTSL1	NA	NA	ENSG00000178031	NA	NA	rs146250839-?	rs146250839	0	146250839	intron_variant	FALSE	NR	4e-8	7.3979400086720375	(African)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	14q32.13	14	95328577	DICER1, CLMN	LINC02292	NA	NA	ENSG00000258630	NA	NA	rs187852559-?	rs187852559	0	187852559	intron_variant	FALSE	NR	9e-10	9.045757490560675	(African)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	16q12.2	16	53768582	AKTIP, RPGRIP1L, FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs11642015-?	rs11642015	0	11642015	intron_variant	FALSE	NR	4e-8	7.3979400086720375	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	1p36.22	1	11879536	NPPA, NPPB	SBF1P2	NA	NA	ENSG00000224904	NA	NA	rs12741980-?	rs12741980	0	12741980	non_coding_transcript_exon_variant	FALSE	NR	3e-11	10.522878745280337	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	3q25.32	3	158119720	RSRC1	RSRC1	NA	NA	ENSG00000174891	NA	NA	rs201851995-?	rs201851995	0	201851995	intron_variant	FALSE	NR	2e-7	6.698970004336019	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	7p15.2	7	27203602	HOTTIP	HOTTIP	NA	NA	ENSG00000243766	NA	NA	rs2023843-?	rs2023843	0	2023843	intron_variant	FALSE	NR	6e-20	19.221848749616356	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	8p23.1	8	9519301	PPP1R3B, TNKS	NA - TNKS	NA	ENSG00000173273	NA	NA	36611	rs35904419-?	rs35904419	0	35904419	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	10q25.3	10	113962652	ADRB1	NHLRC2 - ADRB1	ENSG00000196865	ENSG00000043591	NA	45458	81214	rs180940-?	rs180940	0	180940	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	12p13.1	12	12728121	LRP6, GPR19, APOLD1	APOLD1	NA	NA	ENSG00000178878	NA	NA	rs72656645-?	rs72656645	0	72656645	intron_variant	FALSE	NR	3e-7	6.522878745280337	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers	139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers	12p12.2	12	20201573	SLCO1C1, SLCO1B3, SLCO1B7, SLCO1B1	LINC02468 - NA	ENSG00000256499	NA	NA	65410	NA	rs73073686-?	rs73073686	0	73073686	intergenic_variant	TRUE	NR	2e-17	16.69897000433602	(EA)	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006190	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	4q21.21	4	80243569	FGF5	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675	NA	39240	23070	rs1458038-?	rs1458038	0	1458038	intergenic_variant	TRUE	NA	7e-80	79.15490195998575	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	4q32.1	4	155724361	GUCY1A3-1B3	GUCY1A1	NA	NA	ENSG00000164116	NA	NA	rs13139571-?	rs13139571	0	13139571	intron_variant	FALSE	NA	1e-24	24	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	5p13.3	5	32814922	NPR3, C5orf23	NPR3 - NA	ENSG00000113389	NA	NA	23198	NA	rs1173771-?	rs1173771	0	1173771	regulatory_region_variant	TRUE	NA	3e-28	27.522878745280337	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	5q22.3	5	115054424	TRIM36	NA - TRIM36	NA	ENSG00000152503	NA	NA	70338	rs10077885-?	rs10077885	0	10077885	regulatory_region_variant	TRUE	NA	2e-17	16.69897000433602	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19q13.41	19	51624696	SIGLEC5, RPL9P33	SIGLEC5, SIGLEC5	NA	NA	ENSG00000105501, ENSG00000268500	NA	NA	rs6509558-T	rs6509558	0	6509558	intron_variant	FALSE	0.3123742	2e-18	17.69897000433602	(EA, Sialic acid-binding Ig-like lectin 14)	0.4187	[0.33-0.51] unit increase	Affymetrix [509946]	N	sialic acid-binding Ig-like lectin 14 measurement	http://www.ebi.ac.uk/efo/EFO_0008284	GCST004365	Genome-wide genotyping array	0.3123742	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	9q34.2	9	133278431	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	2407	24039	rs651007-T	rs651007	0	651007	intergenic_variant	TRUE	0.2261785	5e-12	11.301029995663981	(EA, Cadherin-5)	0.3587	[0.26-0.46] unit decrease	Affymetrix [509946]	N	cadherin-5 measurement	http://www.ebi.ac.uk/efo/EFO_0008060	GCST004365	Genome-wide genotyping array	0.2261785	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	9q34.2	9	133278431	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	2407	24039	rs651007-T	rs651007	0	651007	intergenic_variant	TRUE	0.2261785	7e-13	12.154901959985743	(EA, Carbohydrate sulfotransferase 15)	0.3649	[0.27-0.46] unit decrease	Affymetrix [509946]	N	carbohydrate sulfotransferase 15 measurement	http://www.ebi.ac.uk/efo/EFO_0008066	GCST004365	Genome-wide genotyping array	0.2261785	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	9q34.2	9	133278431	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	2407	24039	rs651007-T	rs651007	0	651007	intergenic_variant	TRUE	0.2261785	8e-9	8.096910013008056	(EA, CD109 antigen)	0.2995	[0.2-0.4] unit decrease	Affymetrix [509946]	N	CD109 antigen measurement	http://www.ebi.ac.uk/efo/EFO_0008076	GCST004365	Genome-wide genotyping array	0.2261785	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q28	3	190569373	IL1RAP	IL1RAP	NA	NA	ENSG00000196083	NA	NA	rs9811674-G	rs9811674	0	9811674	intron_variant	FALSE	0.1023069	5e-11	10.301029995663981	(EA, Interleukin-1 Receptor accessory protein)	0.4315	[0.3-0.56] unit increase	Affymetrix [509946]	N	interleukin 1 Receptor accessory protein measurement	http://www.ebi.ac.uk/efo/EFO_0008167	GCST004365	Genome-wide genotyping array	0.1023069	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3p24.3	3	16918160	PLCL2, MIR3714	PLCL2, PLCL2	NA	NA	ENSG00000154822, ENSG00000284017	NA	NA	rs983545-A	rs983545	0	983545	intron_variant	FALSE	0.3482412	2e-12	11.698970004336019	(EA, C-C motif chemokine 17)	0.3198	[0.23-0.41] unit increase	Affymetrix [509946]	N	C-C motif chemokine 17 measurement	http://www.ebi.ac.uk/efo/EFO_0008045	GCST004365	Genome-wide genotyping array	0.3482412	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	NA	NA	NA	MAPKAPK3, DOCK3, ST13P14	NA	NA	NA	NA	NA	NA	rs9869826-C	rs9869826	0	9869826	intron_variant	TRUE	0.09219858	2e-12	11.698970004336019	(EA, Hepatocyte growth factor-like protein)	0.5418	[0.39-0.69] unit decrease	Affymetrix [509946]	N	hepatocyte growth factor-like protein measurement	http://www.ebi.ac.uk/efo/EFO_0008154	GCST004365	Genome-wide genotyping array	0.09219858	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q11.2	17	28283487	KRT18P55	KRT18P55	NA	NA	ENSG00000265480	NA	NA	rs9901901-C	rs9901901	0	9901901	intron_variant	FALSE	0.4773869	2e-10	9.698970004336019	(EA, Abelson tyrosine-protein kinase 2)	0.2762	[0.19-0.36] unit increase	Affymetrix [509946]	N	Abelson tyrosine-protein kinase 2 measurement	http://www.ebi.ac.uk/efo/EFO_0008012	GCST004365	Genome-wide genotyping array	0.4773869	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q11.2	17	28283487	KRT18P55	KRT18P55	NA	NA	ENSG00000265480	NA	NA	rs9901901-C	rs9901901	0	9901901	intron_variant	FALSE	0.4773869	1e-13	13	(EA, Breast cancer anti-estrogen resistance protein 3)	0.3202	[0.24-0.4] unit increase	Affymetrix [509946]	N	breast cancer anti-estrogen resistance protein 3 measurement	http://www.ebi.ac.uk/efo/EFO_0008040	GCST004365	Genome-wide genotyping array	0.4773869	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q11.2	17	28283487	KRT18P55	KRT18P55	NA	NA	ENSG00000265480	NA	NA	rs9901901-C	rs9901901	0	9901901	intron_variant	FALSE	0.4773869	9e-12	11.045757490560675	(EA, Macrophage scavenger receptor types I and II)	0.3044	[0.22-0.39] unit increase	Affymetrix [509946]	N	macrophage scavenger receptor types I and II measurement	http://www.ebi.ac.uk/efo/EFO_0008222	GCST004365	Genome-wide genotyping array	0.4773869	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q11.2	17	28283487	KRT18P55	KRT18P55	NA	NA	ENSG00000265480	NA	NA	rs9901901-C	rs9901901	0	9901901	intron_variant	FALSE	0.4773869	6e-9	8.221848749616356	(EA, Non-receptor tyrosine-protein kinase TYK2)	0.255	[0.17-0.34] unit increase	Affymetrix [509946]	N	non-receptor tyrosine-protein kinase TYK2 measurement	http://www.ebi.ac.uk/efo/EFO_0008251	GCST004365	Genome-wide genotyping array	0.4773869	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	12q24.21	12	115114632	TBX5, TBX3	TBX3 - UBA52P7	ENSG00000135111	ENSG00000241656	NA	430457	477972	rs35444-?	rs35444	0	35444	intergenic_variant	TRUE	NA	4e-46	45.39794000867204	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	15q24.1	15	74785026	CYP1A1, CSK, ULK3	CSK	NA	NA	ENSG00000103653	NA	NA	rs1378942-?	rs1378942	0	1378942	intron_variant	FALSE	NA	8e-33	32.096910013008056	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	15q24.1	15	74833304	CYP1A1, CSK, ULK3	CPLX3 - ULK3	ENSG00000213578	ENSG00000140474	NA	1502	2814	rs6495122-?	rs6495122	0	6495122	regulatory_region_variant	TRUE	NA	5e-30	29.30102999566398	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	15q26.1	15	90894158	FURIN, FES	FES	NA	NA	ENSG00000182511	NA	NA	rs2521501-?	rs2521501	0	2521501	intron_variant	FALSE	NA	3e-40	39.52287874528034	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	19p13.2	19	7252745	INSR	INSR	NA	NA	ENSG00000171105	NA	NA	rs4247374-?	rs4247374	0	4247374	intron_variant	FALSE	NA	6e-19	18.221848749616356	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	20p12.2	20	10988382	JAG1	FAT1P1 - LINC02871	ENSG00000217809	ENSG00000125899	NA	99294	7911	rs1327235-?	rs1327235	0	1327235	intron_variant	TRUE	NA	3e-36	35.52287874528034	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	20q13.32	20	59176062	GNAS, EDN3, ZNF831	ZNF831	NA	NA	ENSG00000124203	NA	NA	rs6015450-?	rs6015450	0	6015450	intron_variant	FALSE	NA	7e-37	36.15490195998574	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q13	2	110852366	ACOXL	ACOXL	NA	NA	ENSG00000153093	NA	NA	rs10197140-C	rs10197140	0	10197140	intron_variant	FALSE	0.339	8e-24	23.096910013008056	NA	0.03776018	[0.03-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.339	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q13	2	111054088	ACOXL	ACOXL, MIR4435-2HG	NA	NA	ENSG00000153093, ENSG00000172965	NA	NA	rs4848370-T	rs4848370	0	4848370	intron_variant	FALSE	0.2755	1e-27	27	NA	0.04324023	[0.035-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2755	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q13	2	111184418	intergenic	MIR4435-2HG	NA	NA	ENSG00000172965	NA	NA	rs616582-C	rs616582	0	616582	intron_variant	FALSE	0.5954	2e-13	12.698970004336019	NA	0.0265234	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.5954	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q13	2	111371516	MIR4435-1HG	MIR4435-2HG	NA	NA	ENSG00000172965	NA	NA	rs2334232-A	rs2334232	0	2334232	intron_variant	FALSE	0.1839	7e-48	47.15490195998574	NA	0.07892772	[0.068-0.09] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.1839	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q13	2	111410354	MIR4435-1HG	MIR4435-2HG	NA	NA	ENSG00000172965	NA	NA	rs62160676-C	rs62160676	0	62160676	intron_variant	FALSE	0.2974	2e-67	66.69897000433602	NA	0.06756394	[0.06-0.075] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2974	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q13	2	111521757	intergenic	MIR4435-2HG, SOCAR	NA	NA	ENSG00000172965, ENSG00000240350	NA	NA	rs112744032-A	rs112744032	0	112744032	intron_variant	FALSE	0.8656	9e-30	29.045757490560675	NA	0.05887251	[0.049-0.069] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.8656	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q31.1	2	173354407	AC092573.2	RPS2P18 - CDCA7	ENSG00000231735	ENSG00000144354	NA	55895	413	rs920112-A	rs920112	0	920112	intron_variant	TRUE	0.0535	5e-9	8.301029995663981	NA	0.04577967	[0.03-0.061] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.0535	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q32.2	2	189568259	SLC40A1	SLC40A1	NA	NA	ENSG00000138449	NA	NA	rs112257498-T	rs112257498	0	112257498	intron_variant	FALSE	0.6134	1e-9	9	NA	0.02233584	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.6134	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q34	2	210675783	CPS1	CPS1	NA	NA	ENSG00000021826	NA	NA	rs1047891-A	rs1047891	0	1047891	missense_variant	FALSE	0.3168	1e-10	10	NA	0.02438928	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.3168	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q37.3	2	238184733	ILKAP	ILKAP	NA	NA	ENSG00000132323	NA	NA	rs35676364-GT	rs35676364	0	35676364	intron_variant	FALSE	0.4829	2e-15	14.698970004336019	NA	0.02864316	[0.022-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.4829	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	2q37.3	2	240571486	RNPEPL1	RNPEPL1	NA	NA	ENSG00000142327	NA	NA	rs78909033-A	rs78909033	0	78909033	intron_variant	FALSE	0.135	3e-9	8.522878745280337	NA	0.03080091	[0.021-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.135	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3p24.3	3	16891490	PLCL2	PLCL2, PLCL2	NA	NA	ENSG00000154822, ENSG00000284017	NA	NA	rs73146904-A	rs73146904	0	73146904	intron_variant	FALSE	0.0736	4e-17	16.397940008672037	NA	0.05733242	[0.044-0.071] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.0736	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3p24.3	3	16929446	PLCL2	PLCL2, PLCL2	NA	NA	ENSG00000154822, ENSG00000284017	NA	NA	rs9821630-G	rs9821630	0	9821630	intron_variant	FALSE	0.2748	6e-14	13.221848749616356	NA	0.02965033	[0.022-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2748	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3p24.3	3	20064181	KAT2B	KAT2B	NA	NA	ENSG00000114166	NA	NA	rs12636078-G	rs12636078	0	12636078	intron_variant	FALSE	0.6875	3e-12	11.522878745280337	NA	0.02681431	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.6875	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3p24.2	3	24293021	THRB	THRB	NA	NA	ENSG00000151090	NA	NA	rs113700287-TTTTG	rs113700287	0	113700287	intron_variant	FALSE	0.6712	7e-77	76.15490195998575	NA	0.07063703	[0.063-0.078] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.6712	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3p21.31	3	49201285	CCDC36	IHO1	NA	NA	ENSG00000173421	NA	NA	rs13091206-G	rs13091206	0	13091206	intron_variant	FALSE	0.7785	8e-12	11.096910013008056	NA	0.02915616	[0.021-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.7785	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3p14.1	3	66402550	LRIG1	LRIG1	NA	NA	ENSG00000144749	NA	NA	rs6147862-T	rs6147862	0	6147862	intron_variant	FALSE	0.6181	7e-14	13.154901959985743	NA	0.02749937	[0.02-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.6181	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3p13	3	71207158	FOXP1	FOXP1	NA	NA	ENSG00000114861	NA	NA	rs17699658-T	rs17699658	0	17699658	intron_variant	FALSE	0.223	6e-12	11.221848749616356	NA	0.02972727	[0.021-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.223	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3p11.1	3	88083829	CGGBP1, RP11-159G9.5	ZNF654, CGGBP1	NA	NA	ENSG00000175105, ENSG00000163320	NA	NA	rs4378991-G	rs4378991	0	4378991	intron_variant	FALSE	0.8313	3e-10	9.522878745280337	NA	0.02965346	[0.02-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.8313	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q12.3	3	101442847	SENP7	SENP7	NA	NA	ENSG00000138468	NA	NA	rs149727694-CA	rs149727694	0	149727694	intron_variant	FALSE	0.1359	2e-9	8.698970004336019	NA	0.03102538	[0.021-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.1359	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q22.1	3	132692324	NPHP3	NPHP3, NPHP3-ACAD11	NA	NA	ENSG00000113971, ENSG00000274810	NA	NA	rs17348614-T	rs17348614	0	17348614	intron_variant	FALSE	0.059	3e-14	13.522878745280337	NA	0.05731955	[0.043-0.072] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.059	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q22.1	3	133748533	TF	INHCAP, TF	NA	NA	ENSG00000242337, ENSG00000091513	NA	NA	rs8177318-A	rs8177318	0	8177318	missense_variant	FALSE	0.0013	2e-18	17.69897000433602	NA	0.4480368	[0.35-0.55] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.0013	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q22.1	3	133757925	TF	TF	NA	NA	ENSG00000091513	NA	NA	rs150854910-T	rs150854910	0	150854910	missense_variant	FALSE	0.0015	3e-13	12.522878745280337	NA	0.3582461	[0.26-0.45] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.0015	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q22.1	3	133765549	TF	TF	NA	NA	ENSG00000091513	NA	NA	rs1358023-C	rs1358023	0	1358023	intron_variant	FALSE	0.3403	7e-17	16.154901959985743	NA	0.03109293	[0.024-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.3403	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	3q23	3	141513090	RASA2	RASA2	NA	NA	ENSG00000155903	NA	NA	rs7651511-A	rs7651511	0	7651511	intron_variant	FALSE	0.3333	4e-26	25.397940008672037	NA	0.03967596	[0.032-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.3333	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q11.2	17	28283487	KRT18P55	KRT18P55	NA	NA	ENSG00000265480	NA	NA	rs9901901-C	rs9901901	0	9901901	intron_variant	FALSE	0.4773869	3e-13	12.522878745280337	(EA, OCIA domain-containing protein 1)	0.3225	[0.24-0.41] unit increase	Affymetrix [509946]	N	OCIA domain-containing protein 1 measurement	http://www.ebi.ac.uk/efo/EFO_0008252	GCST004365	Genome-wide genotyping array	0.4773869	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q11.2	17	28283487	KRT18P55	KRT18P55	NA	NA	ENSG00000265480	NA	NA	rs9901901-C	rs9901901	0	9901901	intron_variant	FALSE	0.4773869	9e-9	8.045757490560675	(EA, Serine/threonine-protein kinase 17B)	0.2523	[0.17-0.34] unit increase	Affymetrix [509946]	N	serine/threonine-protein kinase 17B measurement	http://www.ebi.ac.uk/efo/EFO_0008281	GCST004365	Genome-wide genotyping array	0.4773869	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q12	17	36044969	Intergenic	CCL23 - CCL18	ENSG00000276114	ENSG00000278167	NA	26997	19303	rs9904601-A	rs9904601	0	9904601	intergenic_variant	TRUE	0.1169679	1e-17	17	(EA, C-C motif chemokine 3)	0.5713	[0.44-0.7] unit increase	Affymetrix [509946]	N	C-C motif chemokine 3 measurement	http://www.ebi.ac.uk/efo/EFO_0008051	GCST004365	Genome-wide genotyping array	0.1169679	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	21q21.3	21	26974227	intergenic	ADAMTS5 - DYRK1A	ENSG00000154736	ENSG00000157540	NA	7139	10391346	rs990529-G	rs990529	0	990529	intergenic_variant	TRUE	0.3821464	2e-15	14.698970004336019	(EA, A disintegrin and metalloproteinase with thrombospondin motifs 5)	0.3289	[0.25-0.41] unit increase	Affymetrix [509946]	N	a disintegrin and metalloproteinase with thrombospondin motifs 5 measurement	http://www.ebi.ac.uk/efo/EFO_0008326	GCST004365	Genome-wide genotyping array	0.3821464	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q27.3	3	186852664	NR	ADIPOQ, ADIPOQ-AS1	NA	NA	ENSG00000181092, ENSG00000226482	NA	NA	rs17366568-?	rs17366568	0	17366568	non_coding_transcript_exon_variant	FALSE	NR	6e-7	6.221848749616356	(EA, Adiponectin)	0.2953	NR unit decrease	Affymetrix [509946]	N	adiponectin measurement	http://www.ebi.ac.uk/efo/EFO_0004502	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	9q34.2	9	133278431	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	2407	24039	rs651007-T	rs651007	0	651007	intergenic_variant	TRUE	NR	4e-7	6.3979400086720375	(EA, Intercellular adhesion molecule 1)	NA	NA	Affymetrix [509946]	N	ICAM-1 measurement	http://www.ebi.ac.uk/efo/EFO_0004520	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	9q33.1	9	115042388	NR	TNC, DELEC1	NA	NA	ENSG00000041982, ENSG00000173077	NA	NA	rs7021589-?	rs7021589	0	7021589	intron_variant	FALSE	NR	2e-63	62.69897000433602	(EA, Tenascin)	NA	NA	Affymetrix [509946]	N	tenascin measurement	http://www.ebi.ac.uk/efo/EFO_0008296	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19q13.41	19	51125272	NR	SIGLEC9	NA	NA	ENSG00000129450	NA	NA	rs2075803-?	rs2075803	0	2075803	stop_gained	FALSE	NR	7e-122	121.15490195998575	(EA, Sialic acid-binding Ig-like lectin 9)	NA	NA	Affymetrix [509946]	N	sialic acid-binding Ig-like lectin 9 measurement	http://www.ebi.ac.uk/efo/EFO_0008286	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	5q32	5	150136917	NR	PDGFRB	NA	NA	ENSG00000113721	NA	NA	rs2240781-?	rs2240781	0	2240781	intron_variant	FALSE	NR	5e-161	160.30102999566398	(EA, Platelet-derived growth factor receptor beta)	NA	NA	Affymetrix [509946]	N	platelet-derived growth factor receptor beta measurement	http://www.ebi.ac.uk/efo/EFO_0008265	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19q13.41	19	51210109	NR	MIR8074 - SIGLEC22P	ENSG00000278617	ENSG00000268849	NA	3100	971	rs12985029-?	rs12985029	0	12985029	intergenic_variant	TRUE	NR	2e-66	65.69897000433602	(EA, Myeloid cell surface antigen CD33)	NA	NA	Affymetrix [509946]	N	myeloid cell surface antigen CD33 measurement	http://www.ebi.ac.uk/efo/EFO_0008238	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q28	3	190631021	NR	IL1RAP	NA	NA	ENSG00000196083	NA	NA	rs724608-?	rs724608	0	724608	intron_variant	FALSE	NR	1e-143	143	(EA, Interleukin-1 Receptor accessory protein)	NA	NA	Affymetrix [509946]	N	interleukin 1 Receptor accessory protein measurement	http://www.ebi.ac.uk/efo/EFO_0008167	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q21.3	1	154445939	NR	IL6R	NA	NA	ENSG00000160712	NA	NA	rs11265613-?	rs11265613	0	11265613	intron_variant	FALSE	NR	1e-239	239	(EA, Interleukin-6 receptor subunit alpha)	NA	NA	Affymetrix [509946]	N	interleukin 6 receptor subunit alpha measurement	http://www.ebi.ac.uk/efo/EFO_0008187	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q23.3	1	161671594	NR	FCGR2B	NA	NA	ENSG00000072694	NA	NA	rs6665610-?	rs6665610	0	6665610	synonymous_variant	FALSE	NR	4e-160	159.39794000867204	(EA, Low affinity immunoglobulin gamma Fc region receptor II-a/b)	NA	NA	Affymetrix [509946]	N	low affinity immunoglobulin gamma Fc region receptor II-a/b measurement	http://www.ebi.ac.uk/efo/EFO_0008211	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6q13	6	73749014	NR	CD109	NA	NA	ENSG00000156535	NA	NA	rs9447004-?	rs9447004	0	9447004	intron_variant	FALSE	NR	2e-44	43.69897000433602	(EA, CD109 antigen)	NA	NA	Affymetrix [509946]	N	CD109 antigen measurement	http://www.ebi.ac.uk/efo/EFO_0008076	GCST004365	Genome-wide genotyping array	NA	NA	NA
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr1:93837780:D-AAAAC	chr1:93837780:D	0	NA	NA	TRUE	0.363	1e-8	8	(EA)	0.022	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.363	NA	0.022
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr1:93837780:D-AAAAC	chr1:93837780:D	0	NA	NA	TRUE	NR	6e-10	9.221848749616356	NA	0.022	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.022
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q24.3	1	172380106	NR	PIGC, DNM3	NA	NA	ENSG00000135845, ENSG00000197959	NA	NA	rs7519429-A	rs7519429	0	7519429	intron_variant	FALSE	NR	6e-7	6.221848749616356	NA	0.018	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.018
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q32.1	1	203550066	NR	OPTC - ATP2B4	ENSG00000188770	ENSG00000058668	NA	41117	76721	rs6695980-T	rs6695980	0	6695980	regulatory_region_variant	TRUE	NR	5e-6	5.301029995663981	NA	0.016	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.016
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q41	1	219486326	NR	LYPLAL1-AS1 - NA	ENSG00000228536	NA	NA	26957	NA	rs2791547-A	rs2791547	0	2791547	intergenic_variant	TRUE	0.387	3e-6	5.522878745280337	(EA)	0.018	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.387	NA	0.018
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q41	1	219486326	NR	LYPLAL1-AS1 - NA	ENSG00000228536	NA	NA	26957	NA	rs2791547-A	rs2791547	0	2791547	intergenic_variant	TRUE	NR	7e-7	6.154901959985743	NA	0.018	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.018
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p11.2	2	85333439	NR	Y_RNA - Y_RNA	ENSG00000199964	ENSG00000199964	NA	443	34146	rs10198423-G	rs10198423	0	10198423	intergenic_variant	TRUE	0.356	4e-9	8.397940008672037	(EA)	0.024	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.356	NA	0.024
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p11.2	2	85333439	NR	Y_RNA - Y_RNA	ENSG00000199964	ENSG00000199964	NA	443	34146	rs10198423-G	rs10198423	0	10198423	intergenic_variant	TRUE	NR	5e-9	8.301029995663981	NA	0.023	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.023
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	3q27.2	3	186085743	NR	ETV5	NA	NA	ENSG00000244405	NA	NA	rs112545201-C	rs112545201	0	112545201	intron_variant	FALSE	0.867	1e-14	14	(EA)	0.043	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.867	NA	0.043
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	3q27.2	3	186085743	NR	ETV5	NA	NA	ENSG00000244405	NA	NA	rs112545201-C	rs112545201	0	112545201	intron_variant	FALSE	NR	3e-19	18.522878745280337	NA	0.046	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.046
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr4:106169706:D-TAAC	chr4:106169706:D	0	NA	NA	TRUE	0.95	2e-8	7.698970004336019	(EA)	0.049	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.95	NA	0.049
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr4:106169706:D-TAAC	chr4:106169706:D	0	NA	NA	TRUE	NR	2e-9	8.698970004336019	NA	0.05	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.05
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	5q13.2	5	73050298	NR	FCHO2	NA	NA	ENSG00000157107	NA	NA	rs62362194-T	rs62362194	0	62362194	intron_variant	FALSE	0.882	9e-6	5.045757490560675	(EA)	0.027	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.882	NA	0.027
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	5q13.2	5	73050298	NR	FCHO2	NA	NA	ENSG00000157107	NA	NA	rs62362194-T	rs62362194	0	62362194	intron_variant	FALSE	NR	4e-8	7.3979400086720375	NA	0.03	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.03
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	5q33.3	5	158593417	NR	NA	NA	NA	NA	NA	NA	rs1651274-A	rs1651274	0	1651274	intergenic_variant	TRUE	0.76	4e-7	6.3979400086720375	(EA)	0.022	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.76	NA	0.022
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	5q33.3	5	158593417	NR	NA	NA	NA	NA	NA	NA	rs1651274-A	rs1651274	0	1651274	intergenic_variant	TRUE	NR	3e-9	8.522878745280337	NA	0.023	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.023
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6p21.1	6	42960723	NR	RPL24P4 - GNMT	ENSG00000181524	ENSG00000124713	NA	3958	31	rs10948059-C	rs10948059	0	10948059	regulatory_region_variant	TRUE	0.523	1e-9	9	(EA)	0.023	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.523	NA	0.023
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6p21.1	6	42960723	NR	RPL24P4 - GNMT	ENSG00000181524	ENSG00000124713	NA	3958	31	rs10948059-C	rs10948059	0	10948059	regulatory_region_variant	TRUE	NR	8e-9	8.096910013008056	NA	0.02	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.02
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6p12.2	6	52871258	NR	GSTA11P - GSTA10P	ENSG00000230375	ENSG00000230845	NA	929	1756	rs12529923-C	rs12529923	0	12529923	intergenic_variant	TRUE	0.611	3e-8	7.522878745280337	(EA)	0.021	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.611	NA	0.021
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6p12.2	6	52871258	NR	GSTA11P - GSTA10P	ENSG00000230375	ENSG00000230845	NA	929	1756	rs12529923-C	rs12529923	0	12529923	intergenic_variant	TRUE	NR	1e-8	8	NA	0.021	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.021
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6q25.2	6	153138309	NR	RGS17 - RNA5SP224	ENSG00000091844	ENSG00000201939	NA	7027	20911	rs1281955-T	rs1281955	0	1281955	intergenic_variant	TRUE	0.602	5e-7	6.301029995663981	(EA)	0.019	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.602	NA	0.019
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6q25.2	6	153138309	NR	RGS17 - RNA5SP224	ENSG00000091844	ENSG00000201939	NA	7027	20911	rs1281955-T	rs1281955	0	1281955	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	NA	0.02	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.02
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p14.1	7	38238191	NR	STARD3NL - TRGC2	ENSG00000010270	ENSG00000227191	NA	7521	1389	rs2534596-A	rs2534596	0	2534596	regulatory_region_variant	TRUE	0.624	4e-7	6.3979400086720375	(EA)	0.02	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.624	NA	0.02
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p14.1	7	38238191	NR	STARD3NL - TRGC2	ENSG00000010270	ENSG00000227191	NA	7521	1389	rs2534596-A	rs2534596	0	2534596	regulatory_region_variant	TRUE	NR	2e-8	7.698970004336019	NA	0.02	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.02
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	8q24.12	8	120848349	NR	SNTB1 - NA	ENSG00000172164	NA	NA	35076	NA	rs13248499-G	rs13248499	0	13248499	intergenic_variant	TRUE	0.338	4e-9	8.397940008672037	(EA)	0.024	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.338	NA	0.024
2018-01-12	29095316	Suh Y	2017-11-01	Medicine (Baltimore)	www.ncbi.nlm.nih.gov/pubmed/29095316	Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function.	Lung function (maximal voluntary ventilation)	8,842 Korean ancestry individuals	NA	2q32.1	2	184295785	LOC102724340	NA - MIR548AE1	NA	ENSG00000266808	NA	NA	83190	rs41434646-?	rs41434646	0	41434646	intron_variant	TRUE	NR	3e-8	7.522878745280337	NA	5.95	[NR] unit increase	Affymetrix [2476376] (imputed)	N	maximal voluntary ventilation, pulmonary function measurement	http://www.ebi.ac.uk/efo/EFO_0008431, http://www.ebi.ac.uk/efo/EFO_0003892	GCST005127	Genome-wide genotyping array	NA	5.95	NA
2018-01-12	29095316	Suh Y	2017-11-01	Medicine (Baltimore)	www.ncbi.nlm.nih.gov/pubmed/29095316	Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function.	Lung function (maximal voluntary ventilation)	8,842 Korean ancestry individuals	NA	3p14.2	3	60582520	FHIT	FHIT	NA	NA	ENSG00000189283	NA	NA	rs9833533-?	rs9833533	0	9833533	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	6.68	unit increase	Affymetrix [2476376] (imputed)	N	maximal voluntary ventilation, pulmonary function measurement	http://www.ebi.ac.uk/efo/EFO_0008431, http://www.ebi.ac.uk/efo/EFO_0003892	GCST005127	Genome-wide genotyping array	NA	6.68	NA
2018-01-12	29095316	Suh Y	2017-11-01	Medicine (Baltimore)	www.ncbi.nlm.nih.gov/pubmed/29095316	Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function.	Lung function (maximal voluntary ventilation)	8,842 Korean ancestry individuals	NA	4q27	4	120683279	intergenic	NA - PRDM5	NA	ENSG00000138738	NA	NA	1640	rs1496255-?	rs1496255	0	1496255	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	NA	7.41	unit increase	Affymetrix [2476376] (imputed)	N	maximal voluntary ventilation, pulmonary function measurement	http://www.ebi.ac.uk/efo/EFO_0008431, http://www.ebi.ac.uk/efo/EFO_0003892	GCST005127	Genome-wide genotyping array	NA	7.41	NA
2018-01-12	29095316	Suh Y	2017-11-01	Medicine (Baltimore)	www.ncbi.nlm.nih.gov/pubmed/29095316	Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function.	Lung function (forced expiratory volume in 1 second)	8,842 Korean ancestry individuals	NA	2q32.1	2	184295785	LOC102724340	NA - MIR548AE1	NA	ENSG00000266808	NA	NA	83190	rs41434646-?	rs41434646	0	41434646	intron_variant	TRUE	NR	9e-6	5.045757490560675	NA	4.15	[NR] unit increase	Affymetrix [2476376] (imputed)	N	forced expiratory volume	http://www.ebi.ac.uk/efo/EFO_0004314	GCST005132	Genome-wide genotyping array	NA	4.15	NA
2018-01-12	29095316	Suh Y	2017-11-01	Medicine (Baltimore)	www.ncbi.nlm.nih.gov/pubmed/29095316	Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function.	Lung function (forced expiratory volume in 1 second)	8,842 Korean ancestry individuals	NA	4q27	4	120683279	intergenic	NA - PRDM5	NA	ENSG00000138738	NA	NA	1640	rs1496255-?	rs1496255	0	1496255	intergenic_variant	TRUE	NR	4e-9	8.397940008672037	NA	6.31	unit increase	Affymetrix [2476376] (imputed)	N	forced expiratory volume	http://www.ebi.ac.uk/efo/EFO_0004314	GCST005132	Genome-wide genotyping array	NA	6.31	NA
2018-01-12	29095316	Suh Y	2017-11-01	Medicine (Baltimore)	www.ncbi.nlm.nih.gov/pubmed/29095316	Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function.	Lung function (forced vital capacity)	8,842 Korean ancestry individuals	NA	2q32.1	2	184295785	LOC102724340	NA - MIR548AE1	NA	ENSG00000266808	NA	NA	83190	rs41434646-?	rs41434646	0	41434646	intron_variant	TRUE	NR	1e-7	7	NA	4.16	[NR] unit increase	Affymetrix [2476376] (imputed)	N	vital capacity	http://www.ebi.ac.uk/efo/EFO_0004312	GCST005131	Genome-wide genotyping array	NA	4.16	NA
2018-01-12	29095316	Suh Y	2017-11-01	Medicine (Baltimore)	www.ncbi.nlm.nih.gov/pubmed/29095316	Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function.	Lung function (forced vital capacity)	8,842 Korean ancestry individuals	NA	4q27	4	120683279	intergenic	NA - PRDM5	NA	ENSG00000138738	NA	NA	1640	rs1496255-?	rs1496255	0	1496255	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	NA	5.5	[NR] unit increase	Affymetrix [2476376] (imputed)	N	vital capacity	http://www.ebi.ac.uk/efo/EFO_0004312	GCST005131	Genome-wide genotyping array	NA	5.5	NA
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	8q13.3	8	71557507	MSC	EYA1	NA	NA	ENSG00000104313	NA	NA	rs4738141-G	rs4738141	0	4738141	intron_variant	FALSE	0.24980000000000002	5e-7	6.301029995663981	(EA, women)	0.0298	[0.018-0.041] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.24980000000000002	NA	0.0298
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9q31.1	9	104910084	ABCA1	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs2777795-G	rs2777795	0	2777795	intron_variant	FALSE	0.8982	1e-7	7	(EA, women)	0.0502	[0.032-0.069] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.8982	NA	0.0502
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	11q12.3	11	62627409	EEF1G	GANAB	NA	NA	ENSG00000089597	NA	NA	rs7949030-G	rs7949030	0	7949030	intron_variant	FALSE	0.38260000000000005	5e-8	7.301029995663981	(EA, women)	0.0324	[0.021-0.044] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.38260000000000005	NA	0.0324
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12p11.23	12	26304257	ITPR2, SSPN	SSPN - ITPR2	ENSG00000123096	ENSG00000123104	NA	4967	31095	rs1872992-G	rs1872992	0	1872992	non_coding_transcript_exon_variant	TRUE	0.25429999999999997	3e-17	16.522878745280337	(EA, women)	0.0489	[0.038-0.06] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.25429999999999997	NA	0.0489
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q13.13	12	53948900	HOXC13	HOXC13 - HOXC12	ENSG00000123364	ENSG00000123407	NA	2356	6003	rs1443512-A	rs1443512	0	1443512	regulatory_region_variant	TRUE	0.2348	5e-13	12.301029995663981	(EA, women)	0.0435	[0.032-0.055] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.2348	NA	0.0435
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q24.31	12	123955563	CCDC92	CCDC92	NA	NA	ENSG00000119242	NA	NA	rs4765219-C	rs4765219	0	4765219	intron_variant	FALSE	0.6655	5e-18	17.30102999566398	(EA, women)	0.0456	[0.035-0.056] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6655	NA	0.0456
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	16q23.1	16	75208114	CTRB2	CTRB2 - CTRB1	ENSG00000284810	ENSG00000285346	NA	953	10874	rs889512-C	rs889512	0	889512	intergenic_variant	TRUE	0.8807	3e-8	7.522878745280337	(EA, women)	0.0506	[0.033-0.068] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.8807	NA	0.0506
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	16q23.2	16	81501185	CMIP	CMIP	NA	NA	ENSG00000153815	NA	NA	rs2925979-T	rs2925979	0	2925979	intron_variant	FALSE	0.3008	2e-8	7.698970004336019	(EA, women)	0.0317	[0.021-0.043] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.3008	NA	0.0317
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q24.3	17	70409853	KCNJ2	NA	NA	NA	NA	NA	NA	rs984877-A	rs984877	0	984877	intergenic_variant	TRUE	0.3267	1e-8	8	(EA, women)	0.0308	[0.02-0.041] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.3267	NA	0.0308
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q24.3	17	70512851	KCNJ2	NA	NA	NA	NA	NA	NA	rs173269-A	rs173269	0	173269	intergenic_variant	TRUE	0.3376	3e-8	7.522878745280337	(EA, women)	0.0308	[0.02-0.042] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.3376	NA	0.0308
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	19q13.11	19	33289538	CEBPA	SLC7A10 - CEBPA	ENSG00000130876	ENSG00000245848	NA	63688	10396	rs1423056-G	rs1423056	0	1423056	intergenic_variant	TRUE	0.6765	4e-8	7.3979400086720375	(EA, women)	0.0309	[0.02-0.042] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6765	NA	0.0309
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	20p12.3	20	6645571	BMP2	NA - LINC01713	NA	ENSG00000228482	NA	NA	85509	rs2145272-G	rs2145272	0	2145272	regulatory_region_variant	TRUE	0.34830000000000005	1e-6	6	(EA, women)	0.026	[0.016-0.036] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.34830000000000005	NA	0.026
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	20q13.12	20	46941157	EYA2	EYA2	NA	NA	ENSG00000064655	NA	NA	rs6124901-T	rs6124901	0	6124901	intron_variant	FALSE	0.3016	6e-6	5.221848749616356	(EA, women)	0.0258	[0.015-0.037] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.3016	NA	0.0258
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	22q12.1	22	29054935	ZNRF3, KREMEN1	ZNRF3	NA	NA	ENSG00000183579	NA	NA	rs2179129-A	rs2179129	0	2179129	3_prime_UTR_variant	FALSE	0.5844	1e-9	9	(EA, women)	0.0316	[0.021-0.042] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5844	NA	0.0316
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q11.2	5	56521061	MAP3K1	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs455660-T	rs455660	0	455660	intron_variant	FALSE	0.1962	2e-6	5.698970004336019	(men)	0.035	[0.02-0.05] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.1962	NA	0.035
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q13.3	5	74137483	ARHGEF28	LINC01331	NA	NA	ENSG00000248673	NA	NA	rs167025-A	rs167025	0	167025	intron_variant	FALSE	0.3269	1e-8	8	(men)	0.039	[0.026-0.052] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.3269	NA	0.039
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p25.1	6	6738122	LY86	LY86 - BTF3P7	ENSG00000112799	ENSG00000219986	NA	83139	56793	rs1294409-T	rs1294409	0	1294409	intron_variant	TRUE	0.6258	4e-8	7.3979400086720375	(men)	0.0309	[0.02-0.042] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6258	NA	0.0309
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.32	6	32390424	BTNL2	TSBP1-AS1	NA	NA	ENSG00000225914	NA	NA	rs3129950-G	rs3129950	0	3129950	non_coding_transcript_exon_variant	FALSE	0.8899	4e-9	8.397940008672037	(men)	0.0593	[0.04-0.079] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.8899	NA	0.0593
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q22.33	6	127133993	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs7766106-T	rs7766106	0	7766106	intron_variant	FALSE	0.4821	2e-6	5.698970004336019	(men)	0.0261	[0.015-0.037] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.4821	NA	0.0261
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	25831489	NFE2L3	NA	NA	NA	NA	NA	NA	rs1055144-T	rs1055144	0	1055144	non_coding_transcript_exon_variant	TRUE	0.1997	3e-7	6.522878745280337	(men)	0.0344	[0.021-0.048] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.1997	NA	0.0344
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	27184152	HOXA11	HOXA11	NA	NA	ENSG00000005073	NA	NA	rs7801581-T	rs7801581	0	7801581	intron_variant	FALSE	0.2443	1e-6	6	(men)	0.0315	[0.019-0.044] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.2443	NA	0.0315
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	8q13.3	8	71557507	MSC	EYA1	NA	NA	ENSG00000104313	NA	NA	rs4738141-G	rs4738141	0	4738141	intron_variant	FALSE	0.24980000000000002	8e-6	5.096910013008056	(men)	0.0281	[0.016-0.04] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.24980000000000002	NA	0.0281
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	10q23.33	10	94133757	PLCE1	PLCE1	NA	NA	ENSG00000138193	NA	NA	rs10786152-A	rs10786152	0	10786152	intron_variant	FALSE	0.5231	5e-6	5.301029995663981	(men)	0.0249	[0.014-0.035] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5231	NA	0.0249
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	19q13.11	19	33395448	CEBPA	PEPD	NA	NA	ENSG00000124299	NA	NA	rs7258031-T	rs7258031	0	7258031	intron_variant	FALSE	0.3396	8e-11	10.096910013008056	(men)	0.0382	[0.027-0.05] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.3396	NA	0.0382
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	22q12.1	22	29053489	ZNRF3, KREMEN1	ZNRF3	NA	NA	ENSG00000183579	NA	NA	rs2294239-A	rs2294239	0	2294239	intron_variant	FALSE	0.5834	4e-6	5.3979400086720375	(men)	0.0265	[0.015-0.038] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5834	NA	0.0265
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	25831489	NFE2L3	NA	NA	NA	NA	NA	NA	rs1055144-T	rs1055144	0	1055144	non_coding_transcript_exon_variant	TRUE	0.1997	4e-6	5.3979400086720375	(EA, men)	0.0338	[0.019-0.048] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.1997	NA	0.0338
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	19q13.11	19	33395448	CEBPA	PEPD	NA	NA	ENSG00000124299	NA	NA	rs7258031-T	rs7258031	0	7258031	intron_variant	FALSE	0.3396	2e-9	8.698970004336019	(EA, men)	0.0375	[0.025-0.05] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.3396	NA	0.0375
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	20q11.22	20	35363996	GDF5	UQCC1	NA	NA	ENSG00000101019	NA	NA	rs4911492-A	rs4911492	0	4911492	intron_variant	FALSE	0.606	7e-10	9.154901959985743	(EA, men)	0.0361	[0.025-0.047] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.606	NA	0.0361
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	22q12.1	22	29053489	ZNRF3, KREMEN1	ZNRF3	NA	NA	ENSG00000183579	NA	NA	rs2294239-A	rs2294239	0	2294239	intron_variant	FALSE	0.5834	3e-7	6.522878745280337	(EA, men)	0.0312	[0.019-0.043] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5834	NA	0.0312
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	119031964	TBX15, WARS2	WARS2	NA	NA	ENSG00000116874	NA	NA	rs2645294-T	rs2645294	0	2645294	3_prime_UTR_variant	FALSE	0.5766	2e-14	13.698970004336019	(EA, women)	0.0389	[0.029-0.049] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5766	NA	0.0389
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q24.2	1	170403362	GORAB	HAUS4P1 - GORAB-AS1	ENSG00000226967	ENSG00000231407	NA	32995	57091	rs10919388-C	rs10919388	0	10919388	intergenic_variant	TRUE	0.7242	5e-12	11.301029995663981	(EA, women)	0.0395	[0.028-0.051] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.7242	NA	0.0395
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q24.3	1	172364108	DNM3, PIGC	DNM3	NA	NA	ENSG00000197959	NA	NA	rs2001129-T	rs2001129	0	2001129	intron_variant	FALSE	0.4363	3e-14	13.522878745280337	(EA, women)	0.0387	[0.029-0.049] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.4363	NA	0.0387
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.2	1	176445645	AK096400, PAPPA2	MORF4L1P7 - PAPPA2	ENSG00000225904	ENSG00000116183	NA	77244	17526	rs4650943-A	rs4650943	0	4650943	intron_variant	TRUE	0.5266	5e-7	6.301029995663981	(EA, women)	0.0301	[0.018-0.042] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5266	NA	0.0301
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q41	1	219467338	LYPLAL1	LYPLAL1-AS1 - NA	ENSG00000228536	NA	NA	7969	NA	rs2820436-C	rs2820436	0	2820436	intergenic_variant	TRUE	0.6804	3e-27	26.522878745280337	(EA, women)	0.0587	[0.048-0.069] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6804	NA	0.0587
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p14	2	66555335	MEIS1	MEIS1	NA	NA	ENSG00000143995	NA	NA	rs2300481-T	rs2300481	0	2300481	intron_variant	FALSE	0.3942	1e-6	6	(EA, women)	0.0288	[0.017-0.04] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.3942	NA	0.0288
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p14	2	67625557	ETAA1	LINC02831 - NA	ENSG00000224173	NA	NA	5012	NA	rs7598674-G	rs7598674	0	7598674	intron_variant	TRUE	0.6477999999999999	9e-8	7.045757490560675	(EA, women)	0.0296	[0.019-0.04] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6477999999999999	NA	0.0296
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2q24.3	2	164656581	GRB14, COBLL1	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs10195252-T	rs10195252	0	10195252	intron_variant	FALSE	0.5938	4e-24	23.397940008672037	(EA, women)	0.0554	[0.045-0.066] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5938	NA	0.0554
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2q32.1	2	187251469	CALCRL	NA - RNU6-989P	NA	ENSG00000199626	NA	NA	19229	rs13404250-C	rs13404250	0	13404250	intron_variant	TRUE	0.6693	5e-10	9.301029995663981	(EA, women)	0.0347	[0.024-0.046] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6693	NA	0.0347
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p21.1	3	52588070	PBRM1	PBRM1	NA	NA	ENSG00000163939	NA	NA	rs2590838-G	rs2590838	0	2590838	intron_variant	FALSE	0.48850000000000005	6e-8	7.221848749616356	(EA, women)	0.0276	[0.018-0.038] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.48850000000000005	NA	0.0276
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	NA	NA	NA	PBRM1	NA	NA	NA	NA	NA	NA	rs2710323-T	rs2710323	0	2710323	NA	TRUE	0.5112	5e-8	7.301029995663981	(EA, women)	0.0276	[0.018-0.038] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5112	NA	0.0276
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p14.1	3	64732582	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs2371767-G	rs2371767	0	2371767	intron_variant	FALSE	0.7188	3e-22	21.522878745280337	(EA, women)	0.0558	[0.044-0.067] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.7188	NA	0.0558
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q22.1	3	129615390	PLXND1	PLXND1 - TMCC1	ENSG00000004399	ENSG00000172765	NA	8714	32402	rs10804591-A	rs10804591	0	10804591	intergenic_variant	TRUE	0.7927	1e-15	15	(EA, women)	0.0499	[0.038-0.062] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.7927	NA	0.0499
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q25.31	3	157079820	LEKR1	LEKR1 - LINC00880	ENSG00000197980	ENSG00000243629	NA	33691	1847	rs17451107-T	rs17451107	0	17451107	regulatory_region_variant	TRUE	0.6096	2e-8	7.698970004336019	(EA, women)	0.0299	[0.019-0.04] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6096	NA	0.0299
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q11.2	5	56565039	MAP3K1	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs3936510-T	rs3936510	0	3936510	intron_variant	FALSE	0.1875	3e-11	10.522878745280337	(EA, women)	0.0439	[0.031-0.057] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.1875	NA	0.0439
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p25.1	6	6736698	LY86	LY86 - BTF3P7	ENSG00000112799	ENSG00000219986	NA	81715	58217	rs912057-G	rs912057	0	912057	intron_variant	TRUE	0.6256999999999999	5e-9	8.301029995663981	(EA, women)	0.0308	[0.02-0.041] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6256999999999999	NA	0.0308
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.1	6	43796814	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	10327	48064	rs1358980-T	rs1358980	0	1358980	regulatory_region_variant	TRUE	0.4742	4e-21	20.397940008672037	(EA, women)	0.0531	[0.042-0.064] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.4742	NA	0.0531
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q22.33	6	127133993	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs7766106-T	rs7766106	0	7766106	intron_variant	FALSE	0.4821	6e-24	23.221848749616356	(EA, women)	0.0518	[0.042-0.062] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.4821	NA	0.0518
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	25831489	NFE2L3	NA	NA	NA	NA	NA	NA	rs1055144-T	rs1055144	0	1055144	non_coding_transcript_exon_variant	TRUE	0.1997	5e-11	10.301029995663981	(EA, women)	0.0422	[0.03-0.055] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.1997	NA	0.0422
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7q11.23	7	73471480	PMS2P5	BAZ1B	NA	NA	ENSG00000009954	NA	NA	rs6976930-G	rs6976930	0	6976930	intron_variant	FALSE	0.8132	8e-7	6.096910013008056	(EA, women)	0.0326	[0.02-0.046] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.8132	NA	0.0326
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	8p21.2	8	23738427	NKX2-6	NKX2-6 - NA	ENSG00000180053	NA	NA	31671	NA	rs7004766-T	rs7004766	0	7004766	intron_variant	TRUE	0.7485	2e-11	10.698970004336019	(EA, women)	0.0436	[0.031-0.056] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.7485	NA	0.0436
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	5q15	5	98851806	CHD1	CSNK1A1P3 - CHD1	ENSG00000250162	ENSG00000153922	NA	18095	2179	rs111536497-A	rs111536497	0	111536497	intergenic_variant	TRUE	0.0909	6e-10	9.221848749616356	NA	0.0379827	[0.026-0.05] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.0909	NA	0.0379827
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	5q23.2	5	126755736	RP11-434D11.4	LMNB1-DT	NA	NA	ENSG00000251072	NA	NA	rs2271352-C	rs2271352	0	2271352	intron_variant	FALSE	0.2282	1e-28	28	NA	0.04656434	[0.038-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.2282	NA	0.04656434
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	6q21	6	109298174	CCDC162P	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs9320282-G	rs9320282	0	9320282	intron_variant	FALSE	0.5209	3e-12	11.522878745280337	NA	0.02423685	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.5209	NA	0.02423685
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	6q23.3	6	135178322	MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513	NA	75266	2986	rs9376098-A	rs9376098	0	9376098	intergenic_variant	TRUE	0.3498	1e-12	12	NA	0.02586259	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.3498	NA	0.02586259
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	6p22.3	6	22340162	intergenic	CASC15	NA	NA	ENSG00000272168	NA	NA	rs724744-G	rs724744	0	724744	non_coding_transcript_exon_variant	FALSE	0.5014	3e-15	14.522878745280337	NA	0.02758968	[0.021-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.5014	NA	0.02758968
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	8p23.1	8	6845519	GS1-24F4.2	GS1-24F4.2, GS1-24F4.2	NA	NA	ENSG00000285156, ENSG00000245857	NA	NA	rs11776831-C	rs11776831	0	11776831	intron_variant	FALSE	0.4942	3e-10	9.522878745280337	NA	0.02212378	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.4942	NA	0.02212378
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	8p23.1	8	6966043	DEFA10P	DEFA9P - DEFA10P	ENSG00000284789	ENSG00000233531	NA	5882	2098	rs2702912-G	rs2702912	0	2702912	regulatory_region_variant	TRUE	0.866	3e-17	16.522878745280337	NA	0.04315339	[0.033-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.866	NA	0.04315339
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	8q12.2	8	60733793	CHD7	CHD7	NA	NA	ENSG00000171316	NA	NA	rs35440906-CA	rs35440906	0	35440906	intron_variant	FALSE	0.1869	1e-14	14	NA	0.03437348	[0.026-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.1869	NA	0.03437348
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	8q24.13	8	125511281	RP11-136O12.2	TRIB1 - NA	ENSG00000173334	NA	NA	72878	NA	rs4360309-T	rs4360309	0	4360309	intron_variant	TRUE	0.4888	1e-10	10	NA	0.02297412	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.4888	NA	0.02297412
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	8q24.21	8	129613918	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs10100356-A	rs10100356	0	10100356	intron_variant	FALSE	0.2277	6e-13	12.221848749616356	NA	0.03016674	[0.022-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.2277	NA	0.03016674
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	9q34.13	9	132999365	intergenic	GFI1B - EEF1A1P5	ENSG00000165702	ENSG00000196205	NA	7678	20121	rs550065584-A	rs550065584	0	550065584	regulatory_region_variant	TRUE	0.0022	5e-25	24.30102999566398	NA	0.4180908	[0.34-0.5] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.0022	NA	0.4180908
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1p34.3	1	36478315	CSF3R	CSF3R	NA	NA	ENSG00000119535	NA	NA	rs3917932-G	rs3917932	0	3917932	intron_variant	FALSE	0.5759	2e-17	16.69897000433602	NA	0.03061337	[0.024-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.5759	NA	0.03061337
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	NA	NA	NA	CSF3R	NA	NA	NA	NA	NA	NA	chr1:36952851-A	chr1:36952851	0	NA	NA	TRUE	0.0111	3e-13	12.522878745280337	NA	0.1252956	[0.092-0.159] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0111	NA	0.1252956
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1p32.3	1	51336063	TTC39A	TTC39A	NA	NA	ENSG00000085831	NA	NA	rs55681655-C	rs55681655	0	55681655	intron_variant	FALSE	0.1912	6e-9	8.221848749616356	NA	0.02650856	[0.018-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.1912	NA	0.02650856
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1p32.2	1	56439852	intergenic	LINC01767 - PLPP3	ENSG00000223956	ENSG00000162407	NA	22715	54909	rs1999537-A	rs1999537	0	1999537	intron_variant	TRUE	0.8976	4e-22	21.397940008672037	NA	0.05705475	[0.045-0.069] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.8976	NA	0.05705475
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1p31.3	1	65626887	LEPR	LEPR	NA	NA	ENSG00000116678	NA	NA	rs11208691-G	rs11208691	0	11208691	intron_variant	FALSE	0.371	8e-10	9.096910013008056	NA	0.02270515	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.371	NA	0.02270515
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1p31.3	1	66952344	MIER1	MIER1	NA	NA	ENSG00000198160	NA	NA	rs3008870-T	rs3008870	0	3008870	intron_variant	FALSE	0.7279	3e-13	12.522878745280337	NA	0.02917854	[0.021-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.7279	NA	0.02917854
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	NA	NA	NA	ELTD1	NA	NA	NA	NA	NA	NA	chr1:79411968-A	chr1:79411968	0	NA	NA	TRUE	0.0307	7e-9	8.154901959985743	NA	0.05972101	[0.04-0.08] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0307	NA	0.05972101
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1p22.1	1	92287779	GLMN	GLMN	NA	NA	ENSG00000174842	NA	NA	rs141094656-C	rs141094656	0	141094656	intron_variant	FALSE	0.0164	1e-20	20	NA	0.1395836	[0.11-0.17] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0164	NA	0.1395836
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1p21.2	1	100773738	intergenic	VCAM1 - EXTL2	ENSG00000162692	ENSG00000162694	NA	34693	98634	rs147120681-C	rs147120681	0	147120681	regulatory_region_variant	TRUE	0.4365	8e-15	14.096910013008056	NA	0.0279501	[0.021-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4365	NA	0.0279501
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1p21.2	1	101279090	intergenic	PPIAP7 - LINC01307	ENSG00000173810	ENSG00000231671	NA	7727	44247	rs77046277-G	rs77046277	0	77046277	intergenic_variant	TRUE	0.0016	6e-15	14.221848749616356	NA	0.4025734	[0.3-0.5] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0016	NA	0.4025734
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1q23.1	1	158606310	OR10Z1	OR10Z1	NA	NA	ENSG00000198967	NA	NA	rs860772-C	rs860772	0	860772	intron_variant	FALSE	0.2564	2e-9	8.698970004336019	NA	0.02442757	[0.016-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.2564	NA	0.02442757
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1q23.2	1	159204893	DARC	CADM3-AS1, ACKR1	NA	NA	ENSG00000225670, ENSG00000213088	NA	NA	rs2814778-C	rs2814778	0	2814778	5_prime_UTR_variant	FALSE	0.0019	2e-10	9.698970004336019	NA	0.2653401	[0.18-0.35] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0019	NA	0.2653401
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1q23.2	1	159205704	DARC	ACKR1, CADM3-AS1	NA	NA	ENSG00000213088, ENSG00000225670	NA	NA	rs34599082-T	rs34599082	0	34599082	missense_variant	FALSE	0.0138	4e-20	19.397940008672037	NA	0.1404842	[0.11-0.17] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0138	NA	0.1404842
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1q23.3	1	160818341	LY9	LY9	NA	NA	ENSG00000122224	NA	NA	rs3817407-C	rs3817407	0	3817407	intron_variant	FALSE	0.2199	2e-11	10.698970004336019	NA	0.02876859	[0.02-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.2199	NA	0.02876859
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	9q34.13	9	132989126	GFI1B	GFI1B	NA	NA	ENSG00000165702	NA	NA	rs150813342-T	rs150813342	0	150813342	synonymous_variant	FALSE	0.0084	2e-9	8.698970004336019	NA	0.1187524	[0.08-0.157] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.0084	NA	0.1187524
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	1p22.3	1	87273536	intergenic	LINC02801 - LMO4	ENSG00000284240	ENSG00000143013	NA	8795	55344	rs1537061-C	rs1537061	0	1537061	regulatory_region_variant	TRUE	0.0983	2e-16	15.698970004336019	NA	0.04793435	[0.037-0.059] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.0983	NA	0.04793435
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	1q23.2	1	159205564	DARC	ACKR1, CADM3-AS1	NA	NA	ENSG00000213088, ENSG00000225670	NA	NA	rs12075-A	rs12075	0	12075	missense_variant	FALSE	0.5801	7e-16	15.154901959985743	NA	0.02826954	[0.021-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.5801	NA	0.02826954
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	NA	NA	NA	FCGR3B	NA	NA	NA	NA	NA	NA	chr1:161599779-C	chr1:161599779	0	NA	NA	TRUE	0.3264	5e-11	10.301029995663981	NA	0.02651791	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.3264	NA	0.02651791
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	1q32.1	1	205175235	DSTYK	DSTYK	NA	NA	ENSG00000133059	NA	NA	rs11579220-T	rs11579220	0	11579220	intron_variant	FALSE	0.4382	2e-15	14.698970004336019	NA	0.02771084	[0.021-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.4382	NA	0.02771084
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	1q32.1	1	205684628	SLC45A3	Metazoa_SRP - NUCKS1	ENSG00000278007	ENSG00000069275	NA	321	28194	rs6685188-C	rs6685188	0	6685188	intergenic_variant	TRUE	0.7656	9e-12	11.045757490560675	NA	0.02750701	[0.02-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.7656	NA	0.02750701
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	NA	NA	NA	TMEM206	NA	NA	NA	NA	NA	NA	chr1:212549357-T	chr1:212549357	0	NA	NA	TRUE	0.3792	8e-15	14.096910013008056	NA	0.02804631	[0.021-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.3792	NA	0.02804631
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	1q42.3	1	235939586	RP5-940F7.2	RNU6-968P - LINC02768	ENSG00000206803	ENSG00000229291	NA	24065	18293	rs6701752-A	rs6701752	0	6701752	intergenic_variant	TRUE	0.8924	3e-82	81.52287874528034	NA	0.1080388	[0.097-0.119] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.8924	NA	0.1080388
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	1p36.11	1	26861866	SFN	ZDHHC18 - SFN	ENSG00000204160	ENSG00000175793	NA	4262	1283	rs72307178-T	rs72307178	0	72307178	TF_binding_site_variant	TRUE	0.2088	3e-12	11.522878745280337	NA	0.031632	[0.023-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.2088	NA	0.031632
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	10p15.3	10	914821	LARP4B	LARP4B	NA	NA	ENSG00000107929	NA	NA	rs12762973-G	rs12762973	0	12762973	intron_variant	FALSE	0.2377	3e-18	17.522878745280337	NA	0.03549908	[0.028-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.2377	NA	0.03549908
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	11q24.3	11	128315955	intergenic	LINC02098 - ETS1	ENSG00000272575	ENSG00000134954	NA	74514	142806	rs10893844-C	rs10893844	0	10893844	regulatory_region_variant	TRUE	0.5039	1e-10	10	NA	0.02241265	[0.016-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.5039	NA	0.02241265
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	11p15.5	11	2301968	C11orf21	C11orf21	NA	NA	ENSG00000110665	NA	NA	rs734095-G	rs734095	0	734095	intron_variant	FALSE	0.1138	2e-12	11.698970004336019	NA	0.03869207	[0.028-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.1138	NA	0.03869207
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	11q13.4	11	73235234	P2RY2	P2RY2	NA	NA	ENSG00000175591	NA	NA	rs74472890-C	rs74472890	0	74472890	missense_variant	FALSE	0.05	1e-25	25	NA	0.08349794	[0.068-0.099] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.05	NA	0.08349794
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	11q14.3	11	90218200	CHORDC1	CHORDC1	NA	NA	ENSG00000110172	NA	NA	rs34787918-G	rs34787918	0	34787918	intron_variant	FALSE	0.4473	2e-10	9.698970004336019	NA	0.0223271	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.4473	NA	0.0223271
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	12q14.3	12	66385757	GRIP1	GRIP1	NA	NA	ENSG00000155974	NA	NA	rs61925898-G	rs61925898	0	61925898	intron_variant	FALSE	0.4433	1e-17	17	NA	0.03039219	[0.023-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.4433	NA	0.03039219
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	14q11.2	14	23123308	CEBPE	CEBPE - SLC7A8	ENSG00000092067	ENSG00000092068	NA	4053	1987	rs28479481-T	rs28479481	0	28479481	intergenic_variant	TRUE	0.0616	6e-28	27.221848749616356	NA	0.07908951	[0.065-0.093] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.0616	NA	0.07908951
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	14q11.2	14	23116124	CEBPE	LMLN2 - CEBPE	ENSG00000283654	ENSG00000092067	NA	11135	1182	rs4982731-T	rs4982731	0	4982731	intergenic_variant	TRUE	0.7343	2e-41	40.69897000433602	NA	0.05353112	[0.046-0.061] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.7343	NA	0.05353112
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	3p26.2	3	3161820	CRBN	CRBN	NA	NA	ENSG00000113851	NA	NA	rs17027750-G	rs17027750	0	17027750	intron_variant	FALSE	0.1596	1e-28	28	NA	0.0527062	[0.043-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.1596	NA	0.0527062
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	3q21.3	3	128599154	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	23068	20815	rs6782812-A	rs6782812	0	6782812	intergenic_variant	TRUE	0.893	7e-136	135.15490195998575	NA	0.1395398	[0.13-0.15] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.893	NA	0.1395398
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	3q27.3	3	187738806	BCL6	BCL6	NA	NA	ENSG00000113916	NA	NA	rs3733018-C	rs3733018	0	3733018	intron_variant	FALSE	0.6337	7e-11	10.154901959985743	NA	0.0237749	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.6337	NA	0.0237749
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	3p21.31	3	46209161	CCR3	CCR3	NA	NA	ENSG00000183625	NA	NA	rs3181077-T	rs3181077	0	3181077	intron_variant	FALSE	0.7171	4e-20	19.397940008672037	NA	0.03534761	[0.028-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.7171	NA	0.03534761
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	3p26.2	3	3109662	IL5RA	IL5RA	NA	NA	ENSG00000091181	NA	NA	rs3856850-G	rs3856850	0	3856850	intron_variant	FALSE	0.2775	2e-9	8.698970004336019	NA	0.02333249	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.2775	NA	0.02333249
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	3p26.2	3	3118530	IL5RA	IL5RA	NA	NA	ENSG00000091181	NA	NA	rs10212483-A	rs10212483	0	10212483	intron_variant	FALSE	0.0426	3e-10	9.522878745280337	NA	0.05523778	[0.038-0.072] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.0426	NA	0.05523778
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	4q21.3	4	87008040	AFF1	AFF1	NA	NA	ENSG00000172493	NA	NA	rs340637-T	rs340637	0	340637	intron_variant	FALSE	0.7724	1e-24	24	NA	0.04230716	[0.034-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.7724	NA	0.04230716
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of white cells	171,996 European ancestry individuals	NA	4q21.3	4	87095362	AFF1	AFF1	NA	NA	ENSG00000172493	NA	NA	rs151450-A	rs151450	0	151450	intron_variant	FALSE	0.3994	4e-27	26.397940008672037	NA	0.03818492	[0.031-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007992	GCST004631	Genome-wide genotyping array	0.3994	NA	0.03818492
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Insulin levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	2q36.3	2	226229029	IRS1, NYAP2	NA	NA	NA	NA	NA	NA	rs2943641-T	rs2943641	0	2943641	intergenic_variant	TRUE	0.357	2e-7	6.698970004336019	NA	0.048	[0.03-0.066] unit decrease	Illumina [at least 81396]	N	insulin measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0004467, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005159	Genome-wide genotyping array	0.357	NA	0.048
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Glucagon levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	11p15.2	11	14244067	SPON1	SPON1	NA	NA	ENSG00000262655	NA	NA	rs7102710-C	rs7102710	0	7102710	intron_variant	FALSE	0.092	8e-7	6.096910013008056	NA	0.038	[0.022-0.054] unit decrease	Illumina [at least 81396]	N	glucagon measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005162	Genome-wide genotyping array	0.092	NA	0.038
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Glucagon levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	14q32.13	14	94378610	SERPINA1	SERPINA1, SERPINA1	NA	NA	ENSG00000197249, ENSG00000277377	NA	NA	rs28929474-T	rs28929474	0	28929474	missense_variant	FALSE	0.028	1e-6	6	NA	0.067	[0.04-0.094] unit increase	Illumina [at least 81396]	N	glucagon measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005162	Genome-wide genotyping array	0.028	NA	0.067
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Glucagon levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	1p34.3	1	39357487	MACF1	MACF1	NA	NA	ENSG00000127603	NA	NA	rs142179968-C	rs142179968	0	142179968	missense_variant	FALSE	0.002	2e-6	5.698970004336019	NA	0.215	[0.13-0.3] unit increase	Illumina [at least 81396]	N	glucagon measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005162	Genome-wide genotyping array	0.002	NA	0.215
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Glucagon levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	12q23.3	12	103982846	TDG	TDG	NA	NA	ENSG00000139372	NA	NA	rs140436257-G	rs140436257	0	140436257	missense_variant	FALSE	0.026	4e-6	5.3979400086720375	NA	0.067	[0.038-0.096] unit increase	Illumina [at least 81396]	N	glucagon measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005162	Genome-wide genotyping array	0.026	NA	0.067
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	17p13.1	17	9889451	GLP2R	GLP2R	NA	NA	ENSG00000065325	NA	NA	rs17681684-A	rs17681684	0	17681684	missense_variant	FALSE	0.33	1e-9	9	NA	0.055	[0.037-0.073] unit increase	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005167	Genome-wide genotyping array	0.33	NA	0.055
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	19q13.32	19	45678134	GIPR	GIPR	NA	NA	ENSG00000010310	NA	NA	rs1800437-C	rs1800437	0	1800437	missense_variant	FALSE	0.256	4e-15	14.397940008672037	NA	0.076	[0.056-0.096] unit decrease	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005167	Genome-wide genotyping array	0.256	NA	0.076
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GLP-1 levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	2q31.1	2	173017191	RAPGEF4	RAPGEF4	NA	NA	ENSG00000091428	NA	NA	rs150495482-T	rs150495482	0	150495482	missense_variant	FALSE	0.001	2e-6	5.698970004336019	NA	0.559	[0.33-0.79] unit increase	Illumina [at least 81396]	N	glucagon-like peptide-1 measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008465, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005164	Genome-wide genotyping array	0.001	NA	0.559
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GLP-1 levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	6p21.1	6	43520078	POLR1C	POLR1C	NA	NA	ENSG00000171453	NA	NA	rs201320592-A	rs201320592	0	201320592	missense_variant	FALSE	0.002	4e-6	5.3979400086720375	NA	0.425	[0.24-0.61] unit increase	Illumina [at least 81396]	N	glucagon-like peptide-1 measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008465, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005164	Genome-wide genotyping array	0.002	NA	0.425
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GLP-1 levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	7p22.3	7	1209244	ZFAND2A, UNCX	ZFAND2A-DT - UNCX	ENSG00000229043	ENSG00000164853	NA	43637	23628	rs1568773-G	rs1568773	0	1568773	intergenic_variant	TRUE	0.03	5e-6	5.301029995663981	NA	0.113	[0.064-0.162] unit decrease	Illumina [at least 81396]	N	glucagon-like peptide-1 measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008465, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005164	Genome-wide genotyping array	0.03	NA	0.113
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GLP-1 levels in response to oral glucose tolerance test (fasting)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	8q24.3	8	144504336	GPT	GPT	NA	NA	ENSG00000167701	NA	NA	rs139849083-A	rs139849083	0	139849083	missense_variant	FALSE	0.002	9e-6	5.045757490560675	NA	0.416	[0.23-0.6] unit decrease	Illumina [at least 81396]	N	glucagon-like peptide-1 measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008465, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005164	Genome-wide genotyping array	0.002	NA	0.416
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Insulin levels in response to oral glucose tolerance test (30 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	19q13.32	19	45678134	GIPR	GIPR	NA	NA	ENSG00000010310	NA	NA	rs1800437-C	rs1800437	0	1800437	missense_variant	FALSE	0.258	1e-13	13	NA	0.081	[0.059-0.103] unit decrease	Illumina [at least 81396]	N	insulin measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0004467, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005160	Genome-wide genotyping array	0.258	NA	0.081
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Insulin levels in response to oral glucose tolerance test (30 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	10q23.33	10	92705802	HHEX, EXOC6	HHEX - Y_RNA	ENSG00000152804	ENSG00000199964	NA	10155	4697	rs5015480-T	rs5015480	0	5015480	intergenic_variant	TRUE	0.447	5e-7	6.301029995663981	NA	0.048	[0.028-0.068] unit increase	Illumina [at least 81396]	N	insulin measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0004467, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005160	Genome-wide genotyping array	0.447	NA	0.048
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Insulin levels in response to oral glucose tolerance test (30 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	11q21	11	93526799	SMCO4	SMCO4	NA	NA	ENSG00000166002	NA	NA	rs2248020-A	rs2248020	0	2248020	intron_variant	FALSE	0.204	9e-6	5.045757490560675	NA	0.052	[0.028-0.076] unit increase	Illumina [at least 81396]	N	insulin measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0004467, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005160	Genome-wide genotyping array	0.204	NA	0.052
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Insulin levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	12q24.31	12	124967176	DHX37	DHX37	NA	NA	ENSG00000150990	NA	NA	rs150152903-A	rs150152903	0	150152903	missense_variant	FALSE	0.001	3e-6	5.522878745280337	NA	0.799	[0.46-1.13] unit increase	Illumina [at least 81396]	N	insulin measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0004467, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005161	Genome-wide genotyping array	0.001	NA	0.799
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GLP-1 levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	22q12.3	22	32049959	SLC5A1	SLC5A1	NA	NA	ENSG00000100170	NA	NA	rs17683011-G	rs17683011	0	17683011	missense_variant	FALSE	0.079	4e-8	7.3979400086720375	NA	0.091	[0.058-0.124] unit increase	Illumina [at least 81396]	N	glucagon-like peptide-1 measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008465, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005165	Genome-wide genotyping array	0.079	NA	0.091
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	22q12.3	22	32091713	SLC5A1	SLC5A1	NA	NA	ENSG00000100170	NA	NA	rs17683430-A	rs17683430	0	17683430	missense_variant	FALSE	0.074	3e-18	17.522878745280337	NA	0.122	[0.093-0.147] unit increase	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.074	NA	0.122
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	2q31.1	2	176189453	HOXD1	HOXD1	NA	NA	ENSG00000128645	NA	NA	rs150112597-C	rs150112597	0	150112597	missense_variant	FALSE	0.006	2e-8	7.698970004336019	NA	0.28	[0.18-0.38] unit decrease	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.006	NA	0.28
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	17p13.1	17	7078084	CLEC10A	CLEC10A	NA	NA	ENSG00000132514	NA	NA	rs78714016-A	rs78714016	0	78714016	missense_variant	FALSE	0.002	1e-6	6	NA	0.436	[0.26-0.61] unit decrease	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.002	NA	0.436
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	19q13.32	19	45678134	GIPR	GIPR	NA	NA	ENSG00000010310	NA	NA	rs1800437-C	rs1800437	0	1800437	missense_variant	FALSE	0.258	2e-17	16.69897000433602	NA	0.072	[0.056-0.088] unit decrease	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.258	NA	0.072
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	9q34.2	9	133279427	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	3403	58301	rs635634-T	rs635634	0	635634	intergenic_variant	TRUE	0.195	7e-14	13.154901959985743	NA	0.07	[0.052-0.088] unit decrease	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.195	NA	0.07
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	6p25.1	6	6331640	F13A1	F13A1 - LY86-AS1	ENSG00000124491	ENSG00000216863	NA	10627	14825	rs927332-T	rs927332	0	927332	intergenic_variant	TRUE	0.55	4e-8	7.3979400086720375	NA	0.04	[0.026-0.054] unit increase	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.55	NA	0.04
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	2p21	2	43020088	LOC105374569	NA - LINC01819	NA	ENSG00000231826	NA	NA	7735	rs13421358-C	rs13421358	0	13421358	intergenic_variant	TRUE	0.471	3e-7	6.522878745280337	NA	0.038	[0.024-0.052] unit increase	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.471	NA	0.038
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	1q25.2	1	176670971	PAPPA2	PAPPA2	NA	NA	ENSG00000116183	NA	NA	rs201111080-T	rs201111080	0	201111080	missense_variant	FALSE	0.002	5e-7	6.301029995663981	NA	0.503	[0.31-0.7] unit decrease	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.002	NA	0.503
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	1p12	1	119895261	ADAM30	ADAM30	NA	NA	ENSG00000134249	NA	NA	rs2641348-G	rs2641348	0	2641348	missense_variant	FALSE	0.123	9e-6	5.045757490560675	NA	0.051	[0.029-0.073] unit increase	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.123	NA	0.051
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	10p12.33	10	17346144	ST8SIA6	ST8SIA6	NA	NA	ENSG00000148488	NA	NA	rs359312-T	rs359312	0	359312	intron_variant	FALSE	0.051	9e-6	5.045757490560675	NA	0.076	[0.043-0.109] unit increase	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.051	NA	0.076
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	11q13.4	11	73309801	ARHGEF17	ARHGEF17	NA	NA	ENSG00000110237	NA	NA	rs3741151-T	rs3741151	0	3741151	missense_variant	FALSE	0.138	1e-6	6	NA	0.052	[0.03-0.074] unit increase	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.138	NA	0.052
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	GIP levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	5q35.3	5	181005564	BTNL3	BTNL3	NA	NA	ENSG00000168903	NA	NA	rs73815153-T	rs73815153	0	73815153	missense_variant	FALSE	0.038	3e-6	5.522878745280337	NA	0.088	[0.051-0.125] unit increase	Illumina [at least 81396]	N	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005166	Genome-wide genotyping array	0.038	NA	0.088
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Glucagon levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	4q13.3	4	70689257	UTP3	UTP3	NA	NA	ENSG00000132467	NA	NA	rs111485612-T	rs111485612	0	111485612	missense_variant	FALSE	0.004	7e-6	5.154901959985743	NA	0.159	[0.09-0.228] unit increase	Illumina [at least 81396]	N	glucagon measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005163	Genome-wide genotyping array	0.004	NA	0.159
2018-01-17	29093273	Almgren P	2017-11-02	JCI Insight	www.ncbi.nlm.nih.gov/pubmed/29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	Glucagon levels in response to oral glucose tolerance test (120 minutes)	3,344 Swedish ancestry individuals	4,905 Finnish ancestry individuals	15q22.31	15	63729277	HERC1	HERC1	NA	NA	ENSG00000103657	NA	NA	rs61740450-G	rs61740450	0	61740450	missense_variant	FALSE	0.031	9e-6	5.045757490560675	NA	0.058	[0.033-0.083] unit decrease	Illumina [at least 81396]	N	glucagon measurement, glucose tolerance test	http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307	GCST005163	Genome-wide genotyping array	0.031	NA	0.058
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of granulocytes	170,223 European ancestry individuals	NA	8p23.1	8	6966043	DEFA10P	DEFA9P - DEFA10P	ENSG00000284789	ENSG00000233531	NA	5882	2098	rs2702912-G	rs2702912	0	2702912	regulatory_region_variant	TRUE	0.8659	4e-14	13.397940008672037	NA	0.03901973	[0.029-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007995	GCST004634	Genome-wide genotyping array	0.8659	NA	0.03901973
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of granulocytes	170,223 European ancestry individuals	NA	8q12.2	8	60733793	CHD7	CHD7	NA	NA	ENSG00000171316	NA	NA	rs35440906-CA	rs35440906	0	35440906	intron_variant	FALSE	0.187	3e-21	20.522878745280337	NA	0.04250328	[0.034-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007995	GCST004634	Genome-wide genotyping array	0.187	NA	0.04250328
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of granulocytes	170,223 European ancestry individuals	NA	8q24.13	8	125511281	RP11-136O12.2	TRIB1 - NA	ENSG00000173334	NA	NA	72878	NA	rs4360309-T	rs4360309	0	4360309	intron_variant	TRUE	0.4887	2e-9	8.698970004336019	NA	0.02162174	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007995	GCST004634	Genome-wide genotyping array	0.4887	NA	0.02162174
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of granulocytes	170,223 European ancestry individuals	NA	8q24.21	8	129613918	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs10100356-A	rs10100356	0	10100356	intron_variant	FALSE	0.2277	1e-14	14	NA	0.03262088	[0.024-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007995	GCST004634	Genome-wide genotyping array	0.2277	NA	0.03262088
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Basophil percentage of granulocytes	170,223 European ancestry individuals	NA	9q34.13	9	132999365	intergenic	GFI1B - EEF1A1P5	ENSG00000165702	ENSG00000196205	NA	7678	20121	rs550065584-A	rs550065584	0	550065584	regulatory_region_variant	TRUE	0.0022	2e-22	21.69897000433602	NA	0.3980763	[0.32-0.48] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007995	GCST004634	Genome-wide genotyping array	0.0022	NA	0.3980763
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p21.33	6	31737349	CLIC1	CLIC1, CLIC1, CLIC1, CLIC1, CLIC1, CLIC1, CLIC1	NA	NA	ENSG00000226248, ENSG00000226417, ENSG00000230685, ENSG00000213719, ENSG00000226651, ENSG00000223639, ENSG00000206394	NA	NA	rs145269503-A	rs145269503	0	145269503	intron_variant	FALSE	0.0221	3e-36	35.52287874528034	NA	0.1547004	[0.13-0.18] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0221	NA	0.1547004
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p21.31	6	36381889	ETV7	ETV7	NA	NA	ENSG00000010030	NA	NA	rs3778028-A	rs3778028	0	3778028	intron_variant	FALSE	0.0095	1e-28	28	NA	0.2160177	[0.18-0.25] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0095	NA	0.2160177
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p21.31	6	36429715	PXT1	PXT1	NA	NA	ENSG00000179165	NA	NA	rs515186-G	rs515186	0	515186	intron_variant	FALSE	0.3009	6e-21	20.221848749616356	NA	0.03715279	[0.029-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3009	NA	0.03715279
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p12.3	6	46918107	GPR116	ADGRF5	NA	NA	ENSG00000069122	NA	NA	rs12191082-A	rs12191082	0	12191082	intron_variant	FALSE	0.1365	3e-10	9.522878745280337	NA	0.03324489	[0.023-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1365	NA	0.03324489
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p12.3	6	47641856	intergenic	CD2AP - ADGRF2	ENSG00000198087	ENSG00000164393	NA	14593	14580	rs9473147-G	rs9473147	0	9473147	intergenic_variant	TRUE	0.2675	3e-23	22.522878745280337	NA	0.04077531	[0.033-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2675	NA	0.04077531
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p12.2	6	52416274	EFHC1	EFHC1	NA	NA	ENSG00000096093	NA	NA	rs56032325-A	rs56032325	0	56032325	intron_variant	FALSE	0.0697	2e-16	15.698970004336019	NA	0.05839813	[0.044-0.072] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0697	NA	0.05839813
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p22.2	6	25521693	LRRC16A	CARMIL1	NA	NA	ENSG00000079691	NA	NA	rs34164888-A	rs34164888	0	34164888	intron_variant	FALSE	0.2285	7e-42	41.15490195998574	NA	0.05842709	[0.05-0.067] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2285	NA	0.05842709
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p22.2	6	25528322	LRRC16A	CARMIL1	NA	NA	ENSG00000079691	NA	NA	rs6913974-A	rs6913974	0	6913974	intron_variant	FALSE	0.4413	8e-45	44.096910013008056	NA	0.05111697	[0.044-0.058] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4413	NA	0.05111697
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	NA	NA	NA	TRIM40	NA	NA	NA	NA	NA	NA	chr6:30105154-G	chr6:30105154	0	NA	NA	TRUE	0.0236	2e-19	18.69897000433602	NA	0.1068599	[0.084-0.13] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0236	NA	0.1068599
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p21.33	6	30794316	HCG20, LINC00243	HCG20 - LINC00243	ENSG00000228762	ENSG00000214894	NA	2066	4338	rs3131057-C	rs3131057	0	3131057	intergenic_variant	TRUE	0.6028	8e-17	16.096910013008056	NA	0.03073045	[0.024-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.6028	NA	0.03073045
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p21.33	6	31347735	intergenic	LINC02571 - HLA-B	ENSG00000256166	ENSG00000206450	NA	46093	6137	rs116685461-A	rs116685461	0	116685461	intron_variant	TRUE	0.098	5e-11	10.301029995663981	NA	0.04047215	[0.028-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.098	NA	0.04047215
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p21.33	6	31359924	HLA-B	HLA-B - DHFRP2	ENSG00000206450	ENSG00000228432	NA	2736	6428	rs9378249-G	rs9378249	0	9378249	intergenic_variant	TRUE	0.0655	1e-53	53	NA	0.112675	[0.098-0.127] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0655	NA	0.112675
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	6p21.33	6	31444650	HCP5, LINC01149	LINC01149, LINC01149, LINC01149, LINC01149	NA	NA	ENSG00000231836, ENSG00000234858, ENSG00000226768, ENSG00000230174	NA	NA	rs34624527-A	rs34624527	0	34624527	intron_variant	FALSE	0.4973	2e-15	14.698970004336019	NA	0.02871944	[0.022-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4973	NA	0.02871944
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p36.32	1	3080038	PRDM16	PRDM16	NA	NA	ENSG00000142611	NA	NA	rs1569419-C	rs1569419	0	1569419	intron_variant	FALSE	0.7645	1e-22	22	NA	0.04211349	[0.034-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.7645	NA	0.04211349
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p36.23	1	7734229	CAMTA1	CAMTA1	NA	NA	ENSG00000171735	NA	NA	rs11121012-G	rs11121012	0	11121012	intron_variant	FALSE	0.6446	9e-18	17.045757490560675	NA	0.03271406	[0.025-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.6446	NA	0.03271406
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p36.22	1	10211630	KIF1B	KIF1B	NA	NA	ENSG00000054523	NA	NA	rs11121529-G	rs11121529	0	11121529	5_prime_UTR_variant	FALSE	0.1146	1e-44	44	NA	0.07830624	[0.067-0.089] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1146	NA	0.07830624
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p36.13	1	17393666	PADI6	PADI6, PADI6	NA	NA	ENSG00000280949, ENSG00000276747	NA	NA	rs6695640-G	rs6695640	0	6695640	intron_variant	FALSE	0.6579	3e-10	9.522878745280337	NA	0.02406992	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.6579	NA	0.02406992
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p36.11	1	25551001	LDLRAP1	LDLRAP1	NA	NA	ENSG00000157978	NA	NA	rs75446219-T	rs75446219	0	75446219	intron_variant	FALSE	0.036	4e-16	15.397940008672037	NA	0.08055856	[0.061-0.1] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.036	NA	0.08055856
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p36.11	1	25562931	LDLRAP1	LDLRAP1	NA	NA	ENSG00000157978	NA	NA	rs12096438-T	rs12096438	0	12096438	non_coding_transcript_exon_variant	FALSE	0.5326	5e-25	24.30102999566398	NA	0.03717434	[0.03-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5326	NA	0.03717434
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	1p35.3	1	28877395	RP1-212P9.3	OPRD1 - Y_RNA	ENSG00000116329	ENSG00000199964	NA	6128	4331	rs157198-C	rs157198	0	157198	TF_binding_site_variant	TRUE	0.074	5e-19	18.30102999566398	NA	0.06131747	[0.048-0.075] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.074	NA	0.06131747
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6q24.1	6	139518361	NR	LINC01625 - ATP5PBP6	ENSG00000238099	ENSG00000219806	NA	43703	96077	rs608736-G	rs608736	0	608736	intron_variant	TRUE	0.479	3e-8	7.522878745280337	(EA)	0.021	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.479	NA	0.021
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6q24.1	6	139518361	NR	LINC01625 - ATP5PBP6	ENSG00000238099	ENSG00000219806	NA	43703	96077	rs608736-G	rs608736	0	608736	intron_variant	TRUE	NR	1e-8	8	NA	0.02	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.02
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6q25.3	6	160584357	NR	LPA	NA	NA	ENSG00000198670	NA	NA	rs191555775-A	rs191555775	0	191555775	intron_variant	FALSE	0.901	2e-16	15.698970004336019	(EA)	0.052	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.901	NA	0.052
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6q25.3	6	160584357	NR	LPA	NA	NA	ENSG00000198670	NA	NA	rs191555775-A	rs191555775	0	191555775	intron_variant	FALSE	NR	3e-16	15.522878745280337	NA	0.051	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.051
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	6q26	6	160649958	NR	LPA	NA	NA	ENSG00000198670	NA	NA	rs7759633-G	rs7759633	0	7759633	intron_variant	FALSE	NR	5e-6	5.301029995663981	NA	0.024	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.024
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p22.1	7	6409641	NR	DAGLB	NA	NA	ENSG00000164535	NA	NA	rs702485-A	rs702485	0	702485	3_prime_UTR_variant	FALSE	0.555	4e-7	6.3979400086720375	(EA)	0.019	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.555	NA	0.019
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p22.1	7	6409641	NR	DAGLB	NA	NA	ENSG00000164535	NA	NA	rs702485-A	rs702485	0	702485	3_prime_UTR_variant	FALSE	NR	4e-9	8.397940008672037	NA	0.021	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.021
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p22.1	7	6421679	NR	DAGLB	NA	NA	ENSG00000164535	NA	NA	rs79949326-C	rs79949326	0	79949326	intron_variant	FALSE	0.754	3e-9	8.522878745280337	(EA)	0.026	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.754	NA	0.026
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p22.1	7	6421679	NR	DAGLB	NA	NA	ENSG00000164535	NA	NA	rs79949326-C	rs79949326	0	79949326	intron_variant	FALSE	NR	4e-12	11.397940008672037	NA	0.028	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.028
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p21.1	7	17874977	NR	SNX13	NA	NA	ENSG00000071189	NA	NA	rs6461354-C	rs6461354	0	6461354	intron_variant	FALSE	0.589	8e-7	6.096910013008056	(EA)	0.019	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.589	NA	0.019
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p21.1	7	17874977	NR	SNX13	NA	NA	ENSG00000071189	NA	NA	rs6461354-C	rs6461354	0	6461354	intron_variant	FALSE	NR	6e-11	10.221848749616356	NA	0.023	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.023
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p21.1	7	17879635	NR	SNX13	NA	NA	ENSG00000071189	NA	NA	rs4142995-G	rs4142995	0	4142995	3_prime_UTR_variant	FALSE	0.593	1e-6	6	(EA)	0.019	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.593	NA	0.019
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p21.1	7	17879635	NR	SNX13	NA	NA	ENSG00000071189	NA	NA	rs4142995-G	rs4142995	0	4142995	3_prime_UTR_variant	FALSE	NR	2e-10	9.698970004336019	NA	0.022	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.022
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p12.2	7	50266267	NR	NA - IKZF1	NA	ENSG00000185811	NA	NA	37801	rs4917014-T	rs4917014	0	4917014	regulatory_region_variant	TRUE	0.672	2e-6	5.698970004336019	(EA)	0.019	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.672	NA	0.019
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7p12.2	7	50266267	NR	NA - IKZF1	NA	ENSG00000185811	NA	NA	37801	rs4917014-T	rs4917014	0	4917014	regulatory_region_variant	TRUE	NR	4e-8	7.3979400086720375	NA	0.02	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.02
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7q11.23	7	73520180	NR	BAZ1B	NA	NA	ENSG00000009954	NA	NA	rs7811265-A	rs7811265	0	7811265	intron_variant	FALSE	0.809	1e-12	12	(EA)	0.034	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.809	NA	0.034
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7q11.23	7	73520180	NR	BAZ1B	NA	NA	ENSG00000009954	NA	NA	rs7811265-A	rs7811265	0	7811265	intron_variant	FALSE	NR	4e-12	11.397940008672037	NA	0.031	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.031
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7q11.23	7	73568544	NR	TBL2	NA	NA	ENSG00000106638	NA	NA	rs17145738-C	rs17145738	0	17145738	3_prime_UTR_variant	FALSE	0.88	9e-10	9.045757490560675	(EA)	0.035	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.88	NA	0.035
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7q11.23	7	73568544	NR	TBL2	NA	NA	ENSG00000106638	NA	NA	rs17145738-C	rs17145738	0	17145738	3_prime_UTR_variant	FALSE	NR	8e-11	10.096910013008056	NA	0.035	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.035
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7q11.23	7	73584775	NR	TBL2 - MLXIPL	ENSG00000106638	ENSG00000009950	NA	5984	8419	rs9638182-T	rs9638182	0	9638182	intergenic_variant	TRUE	0.821	1e-12	12	(EA)	0.035	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.821	NA	0.035
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7q11.23	7	73584775	NR	TBL2 - MLXIPL	ENSG00000106638	ENSG00000009950	NA	5984	8419	rs9638182-T	rs9638182	0	9638182	intergenic_variant	TRUE	NR	1e-12	12	NA	0.033	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.033
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7q11.23	7	73602532	NR	MLXIPL	NA	NA	ENSG00000009950	NA	NA	rs13240994-T	rs13240994	0	13240994	intron_variant	FALSE	0.81	8e-13	12.096910013008056	(EA)	0.035	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.81	NA	0.035
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7q11.23	7	73602532	NR	MLXIPL	NA	NA	ENSG00000009950	NA	NA	rs13240994-T	rs13240994	0	13240994	intron_variant	FALSE	NR	2e-13	12.698970004336019	NA	0.034	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.034
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7q11.23	7	73643687	NR	MLXIPL - VPS37D	ENSG00000009950	ENSG00000176428	NA	19144	24144	rs7777102-A	rs7777102	0	7777102	intergenic_variant	TRUE	0.874	3e-9	8.522878745280337	(EA)	0.035	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.874	NA	0.035
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	7q11.23	7	73643687	NR	MLXIPL - VPS37D	ENSG00000009950	ENSG00000176428	NA	19144	24144	rs7777102-A	rs7777102	0	7777102	intergenic_variant	TRUE	NR	1e-9	9	NA	0.032	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.032
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	1p34.2	1	40914768	intergenic	CITED4 - UBE2V1P8	ENSG00000179862	ENSG00000233118	NA	52405	27483	rs4233486-T	rs4233486	0	4233486	intergenic_variant	TRUE	0.64	9e-9	8.045757490560675	(EA)	1.0309278	[1.02-1.05] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.64	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	1p34.1	1	46135245	PIK3R3, LOC101929626	P3R3URF-PIK3R3	NA	NA	ENSG00000278139	NA	NA	rs1707302-G	rs1707302	0	1707302	intron_variant	FALSE	0.659999999999999	3e-8	7.522878745280337	(EA)	1.0416667	[1.02-1.05] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.659999999999999	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	5q22.1	5	111882089	NREP	NREP	NA	NA	ENSG00000134986	NA	NA	rs6882649-T	rs6882649	0	6882649	intron_variant	FALSE	0.659999999999999	4e-9	8.397940008672037	(EA)	1.0309278	[1.01-1.05] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.659999999999999	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	3p13	3	71482962	FOXP1	FOXP1	NA	NA	ENSG00000114861	NA	NA	rs6805189-T	rs6805189	0	6805189	intron_variant	FALSE	0.52	5e-8	7.301029995663981	(EA)	1.0309278	[1.01-1.05] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.52	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	16q13	16	56387075	AMFR	AMFR	NA	NA	ENSG00000159461	NA	NA	rs2432539-A	rs2432539	0	2432539	intron_variant	FALSE	0.4	4e-8	7.3979400086720375	(EA)	1.03	[1.02-1.05] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.4	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	9q33.3	9	126634155	LMX1B	LMX1B	NA	NA	ENSG00000136944	NA	NA	rs10760444-G	rs10760444	0	10760444	intron_variant	FALSE	0.43	9e-9	8.045757490560675	(EA)	1.03	[1.02-1.05] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.43	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	NA	NA	NA	HELQ	NA	NA	NA	NA	NA	NA	4:84370124-TAA	4:84370124	0	NA	NA	TRUE	0.47	2e-9	8.698970004336019	(EA)	1.04	[1.02-1.05] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.47	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	6p22.3	6	20621007	CDKAL1	CDKAL1	NA	NA	ENSG00000145996	NA	NA	rs2223621-T	rs2223621	0	2223621	intron_variant	FALSE	0.38	3e-10	9.522878745280337	(EA)	1.04	[1.02-1.06] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.38	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	19p13.11	19	19434887	GATAD2A, MIR640	GATAD2A	NA	NA	ENSG00000167491	NA	NA	rs2965183-A	rs2965183	0	2965183	intron_variant	FALSE	0.35	6e-12	11.221848749616356	(EA)	1.04	[1.02-1.06] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.35	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	14q32.33	14	104745925	ADSSL1	ADSS1	NA	NA	ENSG00000185100	NA	NA	rs10623258-CTT	rs10623258	0	10623258	non_coding_transcript_exon_variant	FALSE	0.45	2e-8	7.698970004336019	(EA)	1.04	[1.02-1.06] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.45	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	4q22.1	4	88322666	LOC105369192	PPM1K-DT	NA	NA	ENSG00000246375	NA	NA	rs10022462-T	rs10022462	0	10022462	intron_variant	FALSE	0.44	2e-9	8.698970004336019	(EA)	1.04	[1.02-1.06] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.44	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	10q23.33	10	93532431	intergenic	CEP55 - FFAR4	ENSG00000138180	ENSG00000186188	NA	3339	34234	rs140936696-CAA	rs140936696	1	59954380	intergenic_variant	TRUE	0.18	4e-8	7.3979400086720375	(EA)	1.04	[1.02-1.07] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.18	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	5q35.1	5	170164483	intergenic	KRT18P41 - LINC01187	ENSG00000253219	ENSG00000249601	NA	22543	27096	rs4562056-T	rs4562056	0	4562056	intergenic_variant	TRUE	0.33	5e-10	9.301029995663981	(EA)	1.05	[1.03-1.07] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.33	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	12q24.31	12	120394343	intergenic	RPS27P25 - COX6A1	ENSG00000239881	ENSG00000111775	NA	22655	43747	rs206966-T	rs206966	0	206966	intron_variant	TRUE	0.16	4e-8	7.3979400086720375	(EA)	1.05	[1.02-1.07] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.16	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	19q13.32	19	45679774	GIPR	GIPR	NA	NA	ENSG00000010310	NA	NA	rs71338792-AT	rs71338792	0	71338792	intron_variant	FALSE	0.23	4e-9	8.397940008672037	(EA)	1.05	[1.03-1.07] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.23	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	16q12.2	16	54648152	intergenic	LINC02183 - NA	ENSG00000283304	NA	NA	89052	NA	rs28539243-A	rs28539243	0	28539243	intron_variant	TRUE	0.49	9e-15	14.045757490560675	(EA)	1.05	[1.03-1.07] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.49	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	1p22.3	1	87691240	intergenic	PKN2-AS1	NA	NA	ENSG00000237505	NA	NA	rs17426269-A	rs17426269	0	17426269	intron_variant	FALSE	0.15	2e-8	7.698970004336019	(EA)	1.05	[1.02-1.07] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.15	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	8q22.3	8	101466731	intergenic	RN7SL563P - GRHL2	ENSG00000239211	ENSG00000083307	NA	68798	25708	rs514192-A	rs514192	0	514192	intron_variant	TRUE	0.32	6e-9	8.221848749616356	(EA)	1.05	[1.03-1.07] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.32	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	22q13.31	22	45887417	intergenic	ATXN10 - WNT7B	ENSG00000130638	ENSG00000188064	NA	42110	32949	rs28512361-A	rs28512361	0	28512361	intron_variant	TRUE	0.11	2e-8	7.698970004336019	(EA)	1.05	[1.02-1.08] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.11	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	NA	NA	NA	TRIM46	NA	NA	NA	NA	NA	NA	rs4971059-A	rs4971059	0	4971059	intron_variant	TRUE	0.35	5e-11	10.301029995663981	(EA)	1.05	[1.03-1.07] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.35	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	7q21.3	7	94484487	intergenic	COL1A2 - RNU6-1328P	ENSG00000164692	ENSG00000222870	NA	53260	10812	rs17268829-C	rs17268829	0	17268829	intergenic_variant	TRUE	0.28	5e-13	12.301029995663981	(EA)	1.05	[1.03-1.07] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.28	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	20q13.13	20	50329374	intergenic	LINC01271 - RN7SL636P	ENSG00000233077	ENSG00000244376	NA	8032	99816	rs6122906-G	rs6122906	0	6122906	intergenic_variant	TRUE	0.18	3e-10	9.522878745280337	(EA)	1.05	[1.03-1.07] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.18	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	7p15.1	7	28317270	CREB5	CREB5	NA	NA	ENSG00000146592	NA	NA	rs17156577-C	rs17156577	0	17156577	intron_variant	FALSE	0.11	4e-9	8.397940008672037	(EA)	1.05	[1.02-1.08] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.11	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	1p36.13	1	18480845	KLHDC7A	NA - KLHDC7A	NA	ENSG00000179023	NA	NA	85	rs2992756-T	rs2992756	0	2992756	intergenic_variant	TRUE	0.49	2e-15	14.698970004336019	(EA)	1.06	[1.04-1.08] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.49	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	3q23	3	141394018	ZBTB38	ZBTB38	NA	NA	ENSG00000177311	NA	NA	rs34207738-C	rs34207738	0	34207738	intron_variant	FALSE	0.41	3e-15	14.522878745280337	(EA)	1.06	[1.04-1.08] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.41	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	18q12.1	18	32397726	GAREM1	GAREM1	NA	NA	ENSG00000141441	NA	NA	rs117618124-T	rs117618124	0	117618124	intron_variant	FALSE	0.95	6e-12	11.221848749616356	(EA)	1.1235955	[1.09-1.18] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.95	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	6p22.2	6	26680470	intergenic	ZNF322 - NA	ENSG00000181315	NA	NA	20718	NA	rs71557345-G	rs71557345	0	71557345	intron_variant	TRUE	0.929999999999999	4e-10	9.397940008672037	(EA)	1.0869565	[1.04-1.14] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.929999999999999	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	1p34.2	1	41671640	HIVEP3	HIVEP3	NA	NA	ENSG00000127124	NA	NA	rs79724016-T	rs79724016	0	79724016	intron_variant	FALSE	0.97	4e-8	7.3979400086720375	(EA)	1.0752687	[1.03-1.14] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.97	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	5q11.1	5	50345811	intergenic	NA - EMB	NA	ENSG00000170571	NA	NA	50381	rs72749841-T	rs72749841	0	72749841	intergenic_variant	TRUE	0.84	7e-10	9.154901959985743	(EA)	1.0752687	[1.04-1.1] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.84	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	8q23.1	8	105346392	ZFPM3	ZFPM2	NA	NA	ENSG00000169946	NA	NA	rs12546444-A	rs12546444	0	12546444	intron_variant	FALSE	0.9	8e-11	10.096910013008056	(EA)	1.0752687	[1.04-1.1] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.9	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	7q22.1	7	101909160	CUX1	CUX1	NA	NA	ENSG00000257923	NA	NA	rs71559437-G	rs71559437	0	71559437	intron_variant	FALSE	0.88	5e-12	11.301029995663981	(EA)	1.0752687	[1.04-1.1] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.88	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	3p12.1	3	86988393	VGLL3	VGLL3	NA	NA	ENSG00000206538	NA	NA	rs13066793-A	rs13066793	0	13066793	intron_variant	FALSE	0.91	1e-9	9	(EA)	1.0638298	[1.03-1.1] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.91	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	6q23.1	6	130027974	L3MBTL3	L3MBTL3	NA	NA	ENSG00000198945	NA	NA	rs6569648-T	rs6569648	0	6569648	intron_variant	FALSE	0.76	3e-12	11.522878745280337	(EA)	1.0638298	[1.04-1.09] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.76	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	5q31.1	5	133071366	HSPA4	HSPA4	NA	NA	ENSG00000170606	NA	NA	rs6596100-C	rs6596100	0	6596100	intron_variant	FALSE	0.75	8e-9	8.096910013008056	(EA)	1.0638298	[1.04-1.09] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.75	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	9q33.1	9	116551207	ASTN2	ASTN2, ASTN2-AS1	NA	NA	ENSG00000148219, ENSG00000229105	NA	NA	rs1895062-A	rs1895062	0	1895062	intron_variant	FALSE	0.59	1e-14	14	(EA)	1.0638298	[1.05-1.09] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.59	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	4q28.1	4	125922349	intergenic	NA	NA	NA	NA	NA	NA	rs77528541-G	rs77528541	0	77528541	intron_variant	TRUE	0.87	1e-9	9	(EA)	1.0526316	[1.03-1.09] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.87	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	17q21.31	17	46175102	KANSL1	KANSL1, KANSL1, KANSL1	NA	NA	ENSG00000120071, ENSG00000275867, ENSG00000278458	NA	NA	rs2532263-G	rs2532263	0	2532263	intron_variant	FALSE	0.81	7e-13	12.154901959985743	(EA)	1.0526316	[1.03-1.08] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.81	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	22q13.1	22	38172826	PLA2G6	PLA2G6	NA	NA	ENSG00000184381	NA	NA	rs738321-C	rs738321	0	738321	intron_variant	FALSE	0.62	1e-13	13	(EA)	1.0526316	[1.03-1.08] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.62	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	1q41	1	217047232	ESRRG	ESRRG	NA	NA	ENSG00000196482	NA	NA	rs11117758-G	rs11117758	0	11117758	intron_variant	FALSE	0.79	4e-9	8.397940008672037	(EA)	1.0526316	[1.03-1.08] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.79	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	5q11.1	5	50899260	intergenic	PARP8 - LINC02106	ENSG00000151883	ENSG00000251573	NA	52741	69957	rs35951924-A	rs35951924	0	35951924	regulatory_region_variant	TRUE	0.679999999999999	1e-11	11	(EA)	1.0526316	[1.03-1.08] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.679999999999999	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	12q21.31	12	84615658	intergenic	NA	NA	NA	NA	NA	NA	rs202049448-T	rs202049448	0	202049448	intergenic_variant	TRUE	0.659999999999999	3e-8	7.522878745280337	(EA)	1.0526316	[1.03-1.08] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.659999999999999	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	6p22.3	6	16399326	ATXN1	ATXN1	NA	NA	ENSG00000124788	NA	NA	rs3819405-C	rs3819405	0	3819405	intron_variant	FALSE	0.669999999999999	2e-8	7.698970004336019	(EA)	1.0416667	[1.03-1.06] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.669999999999999	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	2q36.3	2	226362236	intergenic	NA	NA	NA	NA	NA	NA	rs12479355-A	rs12479355	0	12479355	intergenic_variant	TRUE	0.79	2e-8	7.698970004336019	(EA)	1.0416667	[1.02-1.06] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.79	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	2p23.3	2	24906604	ADCY3	ADCY3	NA	NA	ENSG00000138031	NA	NA	rs6725517-A	rs6725517	0	6725517	intron_variant	FALSE	0.59	3e-12	11.522878745280337	(EA)	1.0416667	[1.02-1.06] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.59	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	11p15.5	11	803017	PIDD1	PIDD1	NA	NA	ENSG00000177595	NA	NA	rs6597981-G	rs6597981	0	6597981	3_prime_UTR_variant	FALSE	0.52	1e-12	12	(EA)	1.0416667	[1.03-1.06] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.52	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	16q24.2	16	87051631	intergenic	NA - LINC02181	NA	ENSG00000232190	NA	NA	6153	rs4496150-C	rs4496150	0	4496150	intergenic_variant	TRUE	0.75	8e-9	8.096910013008056	(EA)	1.0416667	[1.02-1.06] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.75	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	7p15.3	7	21901342	DNAH11, CDCA7L	CDCA7L, DNAH11	NA	NA	ENSG00000164649, ENSG00000105877	NA	NA	rs7971-A	rs7971	0	7971	3_prime_UTR_variant	FALSE	0.65	2e-8	7.698970004336019	(EA)	1.0416667	[1.02-1.06] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.65	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	1p32.3	1	50380361	intergenic	LINC02808 - HMGB1P45	ENSG00000284696	ENSG00000229316	NA	59169	18464	rs140850326-CAAAGGGCAAGATCTCCTTTTT	rs140850326	0	140850326	intergenic_variant	TRUE	0.51	4e-8	7.3979400086720375	(EA)	1.0309278	[1.01-1.05] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.51	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	19p13.12	19	13843757	intergenic	MIR23AHG - NANOS3	ENSG00000267519	ENSG00000187556	NA	829	18306	rs2594714-G	rs2594714	0	2594714	regulatory_region_variant	TRUE	0.77	1e-8	8	(EA)	1.0309278	[1.01-1.05] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.77	NA	NA
2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	6q14.1	6	80384570	intergenic	RPL17P25 - RPSAP72	ENSG00000219547	ENSG00000219361	NA	10001	85501	rs12207986-A	rs12207986	0	12207986	intergenic_variant	TRUE	0.53	2e-9	8.698970004336019	(EA)	1.0309278	[1.02-1.05] (Oncoarray)	Illumina [~ 11800000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST004988	Genome-wide genotyping array	0.53	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p13.3	1	109612066	GNAT2	GNAT2	NA	NA	ENSG00000134183	NA	NA	rs17024393-?	rs17024393	0	17024393	intron_variant	FALSE	NR	7e-14	13.154901959985743	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.2	1	177920345	SEC16B	LINC01741 - SEC16B	ENSG00000236720	ENSG00000120341	NA	208070	3611	rs543874-?	rs543874	0	543874	intergenic_variant	TRUE	NR	3e-34	33.52287874528034	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q31.1	1	190701754	LOC440704, RGS18	LINC01720	NA	NA	ENSG00000231175	NA	NA	rs1998710-?	rs1998710	0	1998710	intron_variant	FALSE	NR	4e-7	6.3979400086720375	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q32.1	1	201903136	LMOD1, NAV1	LMOD1	NA	NA	ENSG00000163431	NA	NA	rs2820315-?	rs2820315	0	2820315	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p25.3	2	622827	TMEM18	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	76160	41050	rs2867125-?	rs2867125	0	2867125	intergenic_variant	TRUE	NR	5e-52	51.30102999566398	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p23.3	2	24927247	ADCY3	ADCY3 - DNAJC27	ENSG00000138031	ENSG00000115137	NA	7010	16389	rs6752378-?	rs6752378	0	6752378	intergenic_variant	TRUE	NR	3e-17	16.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p16.1	2	58461772	FLJ30838	LINC01122	NA	NA	ENSG00000233723	NA	NA	rs2075171-?	rs2075171	0	2075171	splice_region_variant	FALSE	NR	2e-8	7.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p16.1	2	59102018	LOC730134, FLJ30838	LINC01122 - NA	ENSG00000233723	NA	NA	38252	NA	rs759250-?	rs759250	0	759250	intron_variant	TRUE	NR	9e-10	9.045757490560675	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p24.2	3	25058285	LOC100129045, RARB	RNA5SP125 - NA	ENSG00000201713	NA	NA	33159	NA	rs10510554-?	rs10510554	0	10510554	intron_variant	TRUE	NR	2e-11	10.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p22.1	3	42273163	CCK	CCK - SALL4P6	ENSG00000187094	ENSG00000231280	NA	6978	47842	rs935111-?	rs935111	0	935111	intergenic_variant	TRUE	NR	3e-7	6.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p14.2	3	61250788	FHIT	FHIT	NA	NA	ENSG00000189283	NA	NA	rs2365389-?	rs2365389	0	2365389	intron_variant	FALSE	NR	4e-14	13.397940008672037	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p12.1	3	85811914	CADM2	CADM2-AS2, CADM2	NA	NA	ENSG00000241648, ENSG00000175161	NA	NA	rs9818122-?	rs9818122	0	9818122	intron_variant	FALSE	NR	5e-9	8.301029995663981	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q22.3	3	138389241	MRAS	MRAS	NA	NA	ENSG00000158186	NA	NA	rs1720825-?	rs1720825	0	1720825	intron_variant	FALSE	NR	4e-9	8.397940008672037	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q23	3	141576936	RASA2	RASA2	NA	NA	ENSG00000155903	NA	NA	rs3732869-?	rs3732869	0	3732869	intron_variant	FALSE	NR	3e-10	9.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q27.2	3	186096853	ETV5	ETV5	NA	NA	ENSG00000244405	NA	NA	rs6809651-?	rs6809651	0	6809651	intron_variant	FALSE	NR	1e-16	16	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4p12	4	45180510	GNPDA2	PRDX4P1 - THAP12P9	ENSG00000248987	ENSG00000248320	NA	235549	142743	rs10938397-?	rs10938397	0	10938397	intergenic_variant	TRUE	NR	2e-20	19.69897000433602	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4q24	4	102267552	SLC39A8	SLC39A8	NA	NA	ENSG00000138821	NA	NA	rs13107325-?	rs13107325	0	13107325	missense_variant	FALSE	NR	8e-10	9.096910013008056	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q13.3	5	75738562	C5orf37, POC5	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078	NA	21114	14008	rs7715806-?	rs7715806	0	7715806	intergenic_variant	TRUE	NR	5e-9	8.301029995663981	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q14.3	5	88401716	LOC645323	TMEM161B-AS1	NA	NA	ENSG00000247828	NA	NA	rs6870983-?	rs6870983	0	6870983	intron_variant	FALSE	NR	8e-7	6.096910013008056	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q21.3	5	108103311	FBXL17	FBXL17	NA	NA	ENSG00000145743	NA	NA	rs40067-?	rs40067	0	40067	intron_variant	FALSE	NR	2e-7	6.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q23.2	5	124994829	LOC644659, ZNF608	LINC02240	NA	NA	ENSG00000260192	NA	NA	rs6864049-?	rs6864049	0	6864049	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.31	6	34859308	UHRF1BP1	UHRF1BP1	NA	NA	ENSG00000065060	NA	NA	rs9469913-?	rs9469913	0	9469913	missense_variant	FALSE	NR	2e-6	5.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.2	6	40380914	LRFN2	TDRG1	NA	NA	ENSG00000204091	NA	NA	rs2033529-?	rs2033529	0	2033529	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p12.3	6	50929538	FTHP1, TFAP2B	FTH1P5 - NA	ENSG00000230204	NA	NA	16282	NA	rs4715210-?	rs4715210	0	4715210	regulatory_region_variant	TRUE	NR	6e-17	16.221848749616356	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q16.1	6	97165897	MMS22L	MMS22L	NA	NA	ENSG00000146263	NA	NA	rs4498364-?	rs4498364	0	4498364	intron_variant	FALSE	NR	8e-8	7.096910013008056	NA	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	3p14.3	3	56815721	ARHGEF3	ARHGEF3	NA	NA	ENSG00000163947	NA	NA	rs1354034-C	rs1354034	0	1354034	intron_variant	FALSE	0.6033	0	833	NA	0.2283055	[0.22-0.24] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.6033	NA	0.2283055
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	3p14.3	3	56916027	ARHGEF3	ARHGEF3	NA	NA	ENSG00000163947	NA	NA	rs17825630-A	rs17825630	0	17825630	intron_variant	FALSE	0.1467	1e-29	29	NA	0.06169363	[0.051-0.072] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1467	NA	0.06169363
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	3q13.2	3	113581336	SIDT1	SIDT1	NA	NA	ENSG00000072858	NA	NA	rs2271494-T	rs2271494	0	2271494	intron_variant	FALSE	0.4164	3e-10	9.522878745280337	NA	0.02304263	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4164	NA	0.02304263
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	3q21.1	3	123114156	PDIA5	PDIA5	NA	NA	ENSG00000065485	NA	NA	rs3804749-T	rs3804749	0	3804749	intron_variant	FALSE	0.5927	1e-32	32	NA	0.04409945	[0.037-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5927	NA	0.04409945
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	NA	NA	NA	KALRN	NA	NA	NA	NA	NA	NA	chr3:124303696-T	chr3:124303696	0	NA	NA	TRUE	0.0019	4e-26	25.397940008672037	NA	0.5758883	[0.47-0.68] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0019	NA	0.5758883
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	3q21.2	3	124618265	KALRN	KALRN	NA	NA	ENSG00000160145	NA	NA	rs11920280-G	rs11920280	0	11920280	intron_variant	FALSE	0.4878	6e-53	52.221848749616356	NA	0.05519907	[0.048-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4878	NA	0.05519907
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	3q21.2	3	124658479	KALRN	KALRN	NA	NA	ENSG00000160145	NA	NA	rs56106611-G	rs56106611	0	56106611	missense_variant	FALSE	0.016	2e-54	53.69897000433602	NA	0.2237808	[0.2-0.25] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.016	NA	0.2237808
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	3q21.2	3	124748400	RP11-71H17.9	UMPS	NA	NA	ENSG00000114491	NA	NA	rs689449-A	rs689449	0	689449	3_prime_UTR_variant	FALSE	0.2933	1e-19	19	NA	0.03602182	[0.028-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2933	NA	0.03602182
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	3q26.1	3	167656070	WDR49	WDR49 - PDCD10	ENSG00000174776	ENSG00000114209	NA	2087	27228	rs6807306-G	rs6807306	0	6807306	intergenic_variant	TRUE	0.2614	6e-19	18.221848749616356	NA	0.0364898	[0.028-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2614	NA	0.0364898
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4p16.3	4	3283024	intergenic	MSANTD1 - RGS12	ENSG00000188981	ENSG00000159788	NA	11286	10004	rs6446731-A	rs6446731	0	6446731	regulatory_region_variant	TRUE	0.2843	2e-14	13.698970004336019	NA	0.03076952	[0.023-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2843	NA	0.03076952
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4p16.1	4	6889728	intergenic	KIAA0232 - TBC1D14	ENSG00000170871	ENSG00000132405	NA	5558	19514	rs11731274-G	rs11731274	0	11731274	intergenic_variant	TRUE	0.1761	4e-97	96.39794000867204	NA	0.09967167	[0.09-0.109] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1761	NA	0.09967167
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4p16.1	4	6923070	TBC1D14	TBC1D14	NA	NA	ENSG00000132405	NA	NA	rs116383353-A	rs116383353	0	116383353	intron_variant	FALSE	0.1292	1e-12	12	NA	0.04087826	[0.03-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1292	NA	0.04087826
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4q12	4	56903940	REST	SPINK2 - REST	ENSG00000128040	ENSG00000084093	NA	82198	3936	rs12645070-A	rs12645070	0	12645070	intergenic_variant	TRUE	0.1838	4e-10	9.397940008672037	NA	0.02938713	[0.02-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.1838	NA	0.02938713
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4q21.3	4	87065243	AFF1	AFF1	NA	NA	ENSG00000172493	NA	NA	rs13120301-T	rs13120301	0	13120301	intron_variant	FALSE	0.4202	6e-10	9.221848749616356	NA	0.02267446	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4202	NA	0.02267446
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4q22.3	4	94534108	PDLIM5	PDLIM5	NA	NA	ENSG00000163110	NA	NA	rs11731606-T	rs11731606	0	11731606	intron_variant	FALSE	0.2237	3e-9	8.522878745280337	NA	0.0259829	[0.017-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2237	NA	0.0259829
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4q24	4	101878992	BANK1	BANK1	NA	NA	ENSG00000153064	NA	NA	rs34061204-CA	rs34061204	0	34061204	intron_variant	FALSE	0.3999	2e-15	14.698970004336019	NA	0.02941898	[0.022-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3999	NA	0.02941898
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4q24	4	105112927	RP11-556I14.1	LRPAP1 - TET2	ENSG00000163956	ENSG00000168769	NA	101580481	32948	rs4699154-C	rs4699154	0	4699154	intron_variant	TRUE	0.6902	3e-12	11.522878745280337	NA	0.02736662	[0.02-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.6902	NA	0.02736662
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4q27	4	122263672	KIAA1109	KIAA1109	NA	NA	ENSG00000138688	NA	NA	rs45515895-A	rs45515895	0	45515895	intron_variant	FALSE	0.2051	8e-10	9.096910013008056	NA	0.02758785	[0.019-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.2051	NA	0.02758785
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4q27	4	122595396	intergenic	IL2 - IL21	ENSG00000109471	ENSG00000138684	NA	138671	14712	rs72669198-C	rs72669198	0	72669198	intergenic_variant	TRUE	0.0182	2e-10	9.698970004336019	NA	0.09016081	[0.062-0.118] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0182	NA	0.09016081
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	4q31.3	4	153536367	KIAA0922	TMEM131L	NA	NA	ENSG00000121210	NA	NA	rs2014511-A	rs2014511	0	2014511	intron_variant	FALSE	0.0334	4e-14	13.397940008672037	NA	0.07746759	[0.057-0.098] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.0334	NA	0.07746759
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5p15.33	5	1104823	SLC12A7	SLC12A7, SLC12A7	NA	NA	ENSG00000113504, ENSG00000276482	NA	NA	rs35188965-T	rs35188965	0	35188965	intron_variant	FALSE	0.5805	3e-26	25.522878745280337	NA	0.0387415	[0.032-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.5805	NA	0.0387415
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q12.1	5	60797268	ELOVL7	ELOVL7	NA	NA	ENSG00000164181	NA	NA	rs6449502-C	rs6449502	0	6449502	intron_variant	FALSE	0.8197	6e-27	26.221848749616356	NA	0.05053858	[0.041-0.06] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.8197	NA	0.05053858
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q12.1	5	62239297	intergenic	RN7SKP157 - KIF2A	ENSG00000251983	ENSG00000068796	NA	92351	66865	rs10062757-C	rs10062757	0	10062757	intergenic_variant	TRUE	0.4137	6e-16	15.221848749616356	NA	0.02970023	[0.022-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.4137	NA	0.02970023
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q12.3	5	66620956	MAST4	MAST4	NA	NA	ENSG00000069020	NA	NA	rs10940072-A	rs10940072	0	10940072	intron_variant	FALSE	0.3989	7e-10	9.154901959985743	NA	0.02294515	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.3989	NA	0.02294515
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean platelet volume	164,454 European ancestry individuals	NA	5q13.2	5	72848178	TNPO1	TNPO1	NA	NA	ENSG00000083312	NA	NA	rs34651-T	rs34651	0	34651	5_prime_UTR_variant	FALSE	0.9205	4e-16	15.397940008672037	NA	0.05507057	[0.042-0.068] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean platelet volume	http://www.ebi.ac.uk/efo/EFO_0004584	GCST004599	Genome-wide genotyping array	0.9205	NA	0.05507057
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128100026	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs34709844-A	rs34709844	0	34709844	intron_variant	FALSE	0.153	3e-6	5.522878745280337	NA	0.057	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.153	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128098635	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs6787614-A	rs6787614	0	6787614	intron_variant	FALSE	0.156	3e-6	5.522878745280337	NA	0.057	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.156	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128106463	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs35437840-T	rs35437840	0	35437840	intron_variant	FALSE	0.158	3e-6	5.522878745280337	NA	0.057	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.158	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128118665	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs34545799-T	rs34545799	0	34545799	intron_variant	FALSE	0.158	3e-6	5.522878745280337	NA	0.057	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.158	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128095234	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs36069551-A	rs36069551	0	36069551	intron_variant	FALSE	0.154	3e-6	5.522878745280337	NA	0.057	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.154	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128093949	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs55684215-A	rs55684215	0	55684215	intron_variant	FALSE	0.157	3e-6	5.522878745280337	NA	0.057	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.157	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128093194	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs13091198-T	rs13091198	0	13091198	intron_variant	FALSE	0.154	3e-6	5.522878745280337	NA	0.057	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.154	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78486630	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs12903295-A	rs12903295	0	12903295	intron_variant	FALSE	0.436	8e-11	10.096910013008056	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.436	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144486570	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	85668	rs1813337-A	rs1813337	0	1813337	intron_variant	TRUE	0.347	6e-10	9.221848749616356	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.347	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144350967	Intergenic	NA	NA	NA	NA	NA	NA	rs34991888-T	rs34991888	0	34991888	intron_variant	TRUE	0.276	1e-8	8	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.276	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144348912	Intergenic	NA	NA	NA	NA	NA	NA	rs17709487-T	rs17709487	0	17709487	intron_variant	TRUE	0.276	1e-8	8	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.276	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144365095	Intergenic	NA	NA	NA	NA	NA	NA	rs4240361-A	rs4240361	0	4240361	intron_variant	TRUE	0.275	1e-8	8	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.275	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144365211	Intergenic	NA	NA	NA	NA	NA	NA	rs4240362-C	rs4240362	0	4240362	intron_variant	TRUE	0.275	1e-8	8	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.275	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144399479	Intergenic	NA	NA	NA	NA	NA	NA	rs13128377-T	rs13128377	0	13128377	intron_variant	TRUE	0.277	1e-8	8	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.277	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144392734	Intergenic	NA	NA	NA	NA	NA	NA	rs74877722-T	rs74877722	0	74877722	intron_variant	TRUE	0.277	1e-8	8	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.277	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78447129	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2915695-T	rs2915695	0	2915695	intron_variant	FALSE	0.189	1e-7	7	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.189	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78484114	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs16969894-T	rs16969894	0	16969894	intron_variant	FALSE	0.19	2e-7	6.698970004336019	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.19	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78467006	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs958025-T	rs958025	0	958025	intron_variant	FALSE	0.19	2e-7	6.698970004336019	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.19	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78430177	Intergenic	CRABP1 - IREB2	ENSG00000166426	ENSG00000136381	NA	81952	7254	rs2656056-T	rs2656056	0	2656056	intergenic_variant	TRUE	0.21	2e-7	6.698970004336019	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.21	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78489345	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2036533-A	rs2036533	0	2036533	intron_variant	FALSE	0.189	2e-7	6.698970004336019	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.189	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78433930	Intergenic	CRABP1 - IREB2	ENSG00000166426	ENSG00000136381	NA	85705	3501	rs2036529-A	rs2036529	0	2036529	regulatory_region_variant	TRUE	0.197	2e-7	6.698970004336019	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.197	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	10q23.1	10	80462422	TSPAN14	TSPAN14	NA	NA	ENSG00000108219	NA	NA	rs7100689-A	rs7100689	0	7100689	intron_variant	FALSE	0.77	4e-7	6.3979400086720375	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.77	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128219865	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2811549-T	rs2811549	0	2811549	intron_variant	FALSE	0.16	1e-6	6	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128270076	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2811536-A	rs2811536	0	2811536	intron_variant	FALSE	0.16	1e-6	6	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128119787	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs11707462-C	rs11707462	0	11707462	intron_variant	FALSE	0.161	2e-6	5.698970004336019	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.161	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128128455	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs56050323-A	rs56050323	0	56050323	intron_variant	FALSE	0.161	2e-6	5.698970004336019	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.161	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128122901	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs34172752-A	rs34172752	0	34172752	intron_variant	FALSE	0.153	2e-6	5.698970004336019	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.153	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128122217	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs35531186-T	rs35531186	0	35531186	intron_variant	FALSE	0.153	2e-6	5.698970004336019	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.153	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128098179	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs34562493-T	rs34562493	0	34562493	intron_variant	FALSE	0.153	3e-6	5.522878745280337	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.153	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128096827	RUVBL1	RUVBL1	NA	NA	ENSG00000175792	NA	NA	rs11709377-A	rs11709377	0	11709377	intron_variant	FALSE	0.157	4e-6	5.3979400086720375	NA	0.058	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.157	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144483361	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	88877	rs1961266-A	rs1961266	0	1961266	intron_variant	TRUE	0.347	4e-10	9.397940008672037	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.347	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144480798	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	91440	rs7666298-A	rs7666298	0	7666298	intron_variant	TRUE	0.347	4e-10	9.397940008672037	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.347	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144486505	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	85733	rs75772244-T	rs75772244	1	1813338	intron_variant	TRUE	0.343	5e-10	9.301029995663981	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.343	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144412631	Intergenic	NA	NA	NA	NA	NA	NA	rs17019340-A	rs17019340	0	17019340	intron_variant	TRUE	0.278	7e-9	8.154901959985743	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.278	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144415320	Intergenic	NA	NA	NA	NA	NA	NA	rs4290852-T	rs4290852	0	4290852	intron_variant	TRUE	0.283	1e-8	8	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.283	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78532582	AGPHD1	HYKK	NA	NA	ENSG00000188266	NA	NA	rs12438659-A	rs12438659	0	12438659	intron_variant	FALSE	0.222	2e-8	7.698970004336019	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.222	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78440412	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2938671-A	rs2938671	0	2938671	intron_variant	FALSE	0.198	1e-7	7	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.198	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78437910	Intergenic	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2656070-A	rs2656070	0	2656070	intron_variant	FALSE	0.177	5e-7	6.301029995663981	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.177	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	1q41	1	218401860	TGFB2	TGFB2	NA	NA	ENSG00000092969	NA	NA	rs1317681-A	rs1317681	0	1317681	intron_variant	FALSE	0.844	6e-7	6.221848749616356	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.844	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128240026	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955077-A	rs2955077	0	2955077	intron_variant	FALSE	0.16	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128240343	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955078-A	rs2955078	0	2955078	intron_variant	FALSE	0.16	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128241456	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955081-A	rs2955081	0	2955081	intron_variant	FALSE	0.161	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.161	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128284007	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs6765233-T	rs6765233	0	6765233	intron_variant	FALSE	0.16	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128226479	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955133-T	rs2955133	0	2955133	intron_variant	FALSE	0.16	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128328166	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs11710627-C	rs11710627	0	11710627	intron_variant	FALSE	0.163	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.163	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128328393	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs11710704-A	rs11710704	0	11710704	intron_variant	FALSE	0.163	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.163	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128325077	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs73197388-T	rs73197388	0	73197388	intron_variant	FALSE	0.163	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.163	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128324034	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs55925538-A	rs55925538	0	55925538	intron_variant	FALSE	0.163	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.163	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128207411	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955126-A	rs2955126	0	2955126	intron_variant	FALSE	0.16	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.16	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128210364	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955129-T	rs2955129	0	2955129	intron_variant	FALSE	0.162	1e-6	6	NA	0.059	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.162	NA	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal adenoma (advanced)	636 Austrian ancestry cases, 855 Austrian ancestry controls	NA	16q23.3	16	83274396	Intergenic	CDH13	NA	NA	ENSG00000140945	NA	NA	rs17679617-?	rs17679617	0	17679617	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	1.609	[NR]	Affymetrix [492217] (imputed)	N	colorectal adenoma	http://www.ebi.ac.uk/efo/EFO_0005406	GCST005153	Genome-wide genotyping array	NA	1.609	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal adenoma (advanced)	636 Austrian ancestry cases, 855 Austrian ancestry controls	NA	NA	NA	NA	intergenic	NA	NA	NA	NA	NA	NA	chr12:71074730-?	chr12:71074730	0	NA	NA	TRUE	NA	4e-6	5.3979400086720375	NA	1.667	[NR]	Affymetrix [492217] (imputed)	N	colorectal adenoma	http://www.ebi.ac.uk/efo/EFO_0005406	GCST005153	Genome-wide genotyping array	NA	1.667	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal adenoma (advanced)	636 Austrian ancestry cases, 855 Austrian ancestry controls	NA	1p35.1	1	33874352	Intergenic	CSMD2-AS1, CSMD2	NA	NA	ENSG00000231163, ENSG00000121904	NA	NA	rs17342699-?	rs17342699	0	17342699	intron_variant	FALSE	NA	6e-6	5.221848749616356	NA	3.145	[NR]	Affymetrix [492217] (imputed)	N	colorectal adenoma	http://www.ebi.ac.uk/efo/EFO_0005406	GCST005153	Genome-wide genotyping array	NA	3.145	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal adenoma (advanced)	636 Austrian ancestry cases, 855 Austrian ancestry controls	NA	16q12.1	16	50712015	Intergenic	NOD2	NA	NA	ENSG00000167207	NA	NA	rs2066844-?	rs2066844	0	2066844	missense_variant	FALSE	NA	8e-6	5.096910013008056	NA	2.345	[NR]	Affymetrix [492217] (imputed)	N	colorectal adenoma	http://www.ebi.ac.uk/efo/EFO_0005406	GCST005153	Genome-wide genotyping array	NA	2.345	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal adenoma (advanced)	636 Austrian ancestry cases, 855 Austrian ancestry controls	NA	7p15.3	7	21153722	Intergenic	NA - RN7SL542P	NA	ENSG00000243633	NA	NA	61815	rs2110007-?	rs2110007	0	2110007	intergenic_variant	TRUE	NA	9e-6	5.045757490560675	NA	2.037905	[NR]	Affymetrix [492217] (imputed)	N	colorectal adenoma	http://www.ebi.ac.uk/efo/EFO_0005406	GCST005153	Genome-wide genotyping array	NA	2.037905	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal adenoma (advanced)	636 Austrian ancestry cases, 855 Austrian ancestry controls	NA	7q22.1	7	102841444	Intergenic	FBXL13	NA	NA	ENSG00000161040	NA	NA	rs7781557-?	rs7781557	0	7781557	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	1.5073862	[NR]	Affymetrix [492217] (imputed)	N	colorectal adenoma	http://www.ebi.ac.uk/efo/EFO_0005406	GCST005153	Genome-wide genotyping array	NA	1.5073862	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal adenoma (advanced)	636 Austrian ancestry cases, 855 Austrian ancestry controls	NA	2q37.1	2	233080855	Intergenic	INPP5D, INPP5D	NA	NA	ENSG00000281614, ENSG00000168918	NA	NA	rs7425956-?	rs7425956	0	7425956	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	1.4108351	[NR]	Affymetrix [492217] (imputed)	N	colorectal adenoma	http://www.ebi.ac.uk/efo/EFO_0005406	GCST005153	Genome-wide genotyping array	NA	1.4108351	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal adenoma (advanced)	636 Austrian ancestry cases, 855 Austrian ancestry controls	NA	12q24.11	12	108810035	Intergenic	SSH1	NA	NA	ENSG00000084112	NA	NA	rs4964759-?	rs4964759	0	4964759	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	1.398797	[NR]	Affymetrix [492217] (imputed)	N	colorectal adenoma	http://www.ebi.ac.uk/efo/EFO_0005406	GCST005153	Genome-wide genotyping array	NA	1.398797	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	15q25.3	15	87729238	Intergenic	NA	NA	NA	NA	NA	NA	rs4454940-?	rs4454940	0	4454940	regulatory_region_variant	TRUE	NR	7e-6	5.154901959985743	NA	1.3583266	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.3583266	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	12q21.1	12	74853201	Intergenic	NA	NA	NA	NA	NA	NA	rs4471510-?	rs4471510	0	4471510	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	NA	1.388	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.388	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	3p25.3	3	8880774	Intergenic	RAD18	NA	NA	ENSG00000070950	NA	NA	rs45449196-?	rs45449196	0	45449196	3_prime_UTR_variant	FALSE	NR	9e-6	5.045757490560675	NA	2.28	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	2.28	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	6q22.31	6	123998565	Intergenic	NKAIN2	NA	NA	ENSG00000188580	NA	NA	rs4574657-?	rs4574657	0	4574657	intron_variant	FALSE	NR	8e-6	5.096910013008056	NA	1.855	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.855	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	3p22.2	3	39195699	Intergenic	XIRP1 - DSTNP4	ENSG00000168334	ENSG00000215034	NA	3103	18500	rs4676482-?	rs4676482	0	4676482	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	NA	1.5151515	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.5151515	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	3p24.1	3	28251869	Intergenic	CMC1	NA	NA	ENSG00000187118	NA	NA	rs4680748-?	rs4680748	0	4680748	intron_variant	FALSE	NR	2e-6	5.698970004336019	NA	1.3867704	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.3867704	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	6p21.1	6	46076500	Intergenic	CLIC5	NA	NA	ENSG00000112782	NA	NA	rs4714902-?	rs4714902	0	4714902	intron_variant	FALSE	NR	5e-6	5.301029995663981	NA	1.363	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.363	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	10q26.2	10	126997259	Intergenic	DOCK1	NA	NA	ENSG00000150760	NA	NA	rs4751006-?	rs4751006	0	4751006	intron_variant	FALSE	NR	9e-6	5.045757490560675	NA	1.7289073	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.7289073	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	11p15.3	11	12893432	Intergenic	TEAD1	NA	NA	ENSG00000187079	NA	NA	rs4757965-?	rs4757965	0	4757965	intron_variant	FALSE	NR	3e-7	6.522878745280337	NA	1.961169	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.961169	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	17q24.3	17	71391768	Intergenic	RNU7-155P - NA	ENSG00000238759	NA	NA	93550	NA	rs4793259-?	rs4793259	0	4793259	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	NA	1.6920472	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.6920472	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	17p13.1	17	6779565	Intergenic	FBXO39	NA	NA	ENSG00000177294	NA	NA	rs4796354-?	rs4796354	0	4796354	intron_variant	FALSE	NR	1e-6	6	NA	1.389	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.389	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	3p14.2	3	59771758	Intergenic	FHIT	NA	NA	ENSG00000189283	NA	NA	rs49413-?	rs49413	0	49413	intron_variant	FALSE	NR	8e-6	5.096910013008056	NA	1.405	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.405	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	10q21.1	10	58114606	Intergenic	NA - IPMK	NA	ENSG00000151151	NA	NA	76911	rs4948237-?	rs4948237	0	4948237	intergenic_variant	TRUE	NR	8e-6	5.096910013008056	NA	2.2862368	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	2.2862368	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	3q26.31	3	172371463	Intergenic	FNDC3B	NA	NA	ENSG00000075420	NA	NA	rs553685-?	rs553685	0	553685	intron_variant	FALSE	NR	1e-6	6	NA	2.2507315	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	2.2507315	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	20q13.13	20	49459375	Intergenic	KCNB1	NA	NA	ENSG00000158445	NA	NA	rs579113-?	rs579113	0	579113	intron_variant	FALSE	NR	6e-6	5.221848749616356	NA	1.347	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.347	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	20p13	20	4433957	Intergenic	NA	NA	NA	NA	NA	NA	rs6052563-?	rs6052563	0	6052563	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	NA	1.945	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.945	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colonoscopy-negative controls vs population controls	855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls	NA	20p11.23	20	21006870	Intergenic	NA - LINC00237	NA	ENSG00000225127	NA	NA	78706	rs6082278-?	rs6082278	0	6082278	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	NA	1.367	[NR]	Affymetrix [492217] (imputed)	N	colorectal health	http://www.ebi.ac.uk/efo/EFO_0008460	GCST005147	Genome-wide genotyping array	NA	1.367	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	17q24.3	17	69228706	ABCA10	ABCA10	NA	NA	ENSG00000154263	NA	NA	rs9302891-?	rs9302891	0	9302891	5_prime_UTR_variant	FALSE	NR	7e-6	5.154901959985743	(adjusted for dose, GFR & AST)	6.616	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	6.616	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	10q25.3	10	114642349	ABLIM1	ABLIM1	NA	NA	ENSG00000099204	NA	NA	rs2483519-?	rs2483519	0	2483519	intron_variant	FALSE	NR	2e-6	5.698970004336019	(adjusted for dose, GFR & AST)	2.729	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	2.729	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	13q33.3	13	107030239	ARGLU1, FAM155A	LINC00393 - NA	ENSG00000224853	NA	NA	33368348	NA	rs16969611-?	rs16969611	0	16969611	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	(adjusted for dose, GFR & AST)	3.629	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	3.629	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	3q26.1	3	166329716	BCHE, ZBBX	NA	NA	NA	NA	NA	NA	rs1574560-?	rs1574560	0	1574560	intergenic_variant	TRUE	NR	6e-7	6.221848749616356	(adjusted for dose, GFR & AST)	3.049	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	3.049	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	14q24.3	14	76937083	C14orf166B, IRF2BPL	RN7SKP17 - LINC01629	ENSG00000223174	ENSG00000258602	NA	46470	22555	rs2056859-?	rs2056859	0	2056859	regulatory_region_variant	TRUE	NR	2e-6	5.698970004336019	NA	11.03	unit increase (EA, Dutch cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	11.03	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	10q22.2	10	73894042	CAMK2G, C10orf55	CAMK2G - PLAU	ENSG00000148660	ENSG00000122861	NA	19451	15135	rs17741873-?	rs17741873	0	17741873	intergenic_variant	TRUE	NR	8e-6	5.096910013008056	(adjusted for dose, GFR & AST)	2.888	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	2.888	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	2p16.1	2	57804114	CCDC85A, VRK2	ACTG1P22 - NA	ENSG00000271615	NA	NA	38062	NA	rs1851138-?	rs1851138	0	1851138	intergenic_variant	TRUE	NR	6e-6	5.221848749616356	NA	6.833	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	6.833	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	1p36.12	1	20620263	CDA, PINK1	CDA - PINK1	ENSG00000158825	ENSG00000158828	NA	1360	13195	rs1614627-?	rs1614627	0	1614627	intergenic_variant	TRUE	NR	6e-7	6.221848749616356	NA	7.424	unit increase (EA, Dutch cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	7.424	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	10p14	10	8603200	GATA3	KRT8P37 - CHCHD3P1	ENSG00000213771	ENSG00000236420	NA	88094	16733	rs9787692-?	rs9787692	0	9787692	intergenic_variant	TRUE	NR	7e-7	6.154901959985743	(adjusted for dose, GFR & AST)	3.672	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	3.672	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	4q34.1	4	174644094	GLRA3	GLRA3	NA	NA	ENSG00000145451	NA	NA	rs4235212-?	rs4235212	0	4235212	intron_variant	FALSE	NR	6e-6	5.221848749616356	NA	2.503	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	2.503	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	3p26.1	3	7956266	GRM7, LOC100288428	LMCD1-AS1	NA	NA	ENSG00000227110	NA	NA	rs10510382-?	rs10510382	0	10510382	intron_variant	FALSE	NR	6e-6	5.221848749616356	NA	3.033	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	3.033	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	16p12.1	16	25955783	HS3ST4	HS3ST4	NA	NA	ENSG00000182601	NA	NA	rs9938946-?	rs9938946	0	9938946	intron_variant	FALSE	NR	3e-6	5.522878745280337	NA	3.774	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	3.774	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	18q11.2	18	26521596	KCTD1	KCTD1	NA	NA	ENSG00000134504	NA	NA	rs8083427-?	rs8083427	0	8083427	intron_variant	FALSE	NR	3e-6	5.522878745280337	NA	5.467	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	5.467	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	10p11.23	10	30080931	KIAA1462, MTPAP	JCAD	NA	NA	ENSG00000165757	NA	NA	rs2505127-?	rs2505127	0	2505127	intron_variant	FALSE	NR	6e-6	5.221848749616356	(adjusted for dose, GFR & AST)	5.005	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	5.005	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	1p22.3	1	87773925	LOC100505768, PKN2	PKN2-AS1	NA	NA	ENSG00000237505	NA	NA	rs17130142-?	rs17130142	0	17130142	intron_variant	FALSE	NR	2e-7	6.698970004336019	NA	8.641	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	8.641	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	1p31.1	1	81208812	LPHN2	NA - RN7SKP247	NA	ENSG00000223026	NA	NA	42977	rs17131753-?	rs17131753	0	17131753	non_coding_transcript_exon_variant	TRUE	NR	7e-6	5.154901959985743	NA	7.784	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	7.784	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	18q23	18	77003313	MBP	MBP	NA	NA	ENSG00000197971	NA	NA	rs470903-?	rs470903	0	470903	non_coding_transcript_exon_variant	FALSE	NR	3e-6	5.522878745280337	(adjusted for dose, GFR & AST)	5.453	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	5.453	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	13q34	13	109657033	MYO16, IRS2	NA - LINC00676	NA	ENSG00000234854	NA	NA	71249	rs11840576-?	rs11840576	0	11840576	intron_variant	TRUE	NR	2e-6	5.698970004336019	NA	8.684	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	8.684	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	12p13.33	12	674318	NINJ2, WNK1	NINJ2-AS1 - LINC02455	ENSG00000177406	ENSG00000256672	NA	10122	483	rs12425791-?	rs12425791	0	12425791	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	NA	2.026	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	2.026	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	14q31.1	14	79888998	NRXN3, DIO2	NRXN3 - NA	ENSG00000021645	NA	NA	20707	NA	rs2205226-?	rs2205226	0	2205226	intergenic_variant	TRUE	NR	5e-6	5.301029995663981	NA	4.956	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	4.956	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	8q23.1	8	106314611	OXR1	OXR1	NA	NA	ENSG00000164830	NA	NA	rs7013285-?	rs7013285	0	7013285	intron_variant	FALSE	NR	3e-6	5.522878745280337	(adjusted for dose, GFR & AST)	3.067	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	3.067	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	1q22	1	156219495	PMF1, PMF1-BGLAP	PMF1-BGLAP, PMF1	NA	NA	ENSG00000260238, ENSG00000160783	NA	NA	rs2758596-?	rs2758596	0	2758596	intron_variant	FALSE	NR	6e-6	5.221848749616356	NA	4.844	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	4.844	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	7q33	7	137259485	PTN	PTN	NA	NA	ENSG00000105894	NA	NA	rs17169015-?	rs17169015	0	17169015	intron_variant	FALSE	NR	5e-6	5.301029995663981	NA	18.28	unit increase (EA, Dutch cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	18.28	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	1p35.3	1	29429306	PTPRU, MATN1	LINC01756 - NA	ENSG00000230523	NA	NA	79192	NA	rs16838233-?	rs16838233	0	16838233	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	NA	5.346	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	5.346	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	14q11.2	14	20698124	RNASE4	EGILA, RNASE4, ANG	NA	NA	ENSG00000258451, ENSG00000258818, ENSG00000214274	NA	NA	rs17211649-?	rs17211649	0	17211649	intron_variant	FALSE	NR	2e-6	5.698970004336019	NA	14.22	unit increase (EA, Dutch cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	14.22	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	1q23.3	1	161352208	SDHC	SDHC	NA	NA	ENSG00000143252	NA	NA	rs12140361-?	rs12140361	0	12140361	intron_variant	FALSE	NR	3e-6	5.522878745280337	(adjusted for dose, GFR & AST)	7.098	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	7.098	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	1q22	1	156193927	SLC25A44	SEMA4A - SLC25A44	ENSG00000196189	ENSG00000160785	NA	16175	5	rs2241111-?	rs2241111	0	2241111	TF_binding_site_variant	TRUE	NR	6e-6	5.221848749616356	NA	4.844	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	4.844	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	15q25.2	15	81554938	TMC3, MEX3B	TMC3-AS1 - NA	ENSG00000259343	NA	NA	36738	NA	rs969348-?	rs969348	0	969348	intron_variant	TRUE	NR	6e-6	5.221848749616356	NA	5.866	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	5.866	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	2q14.3	2	122620366	TSN, CNTNAP5	NA	NA	NA	NA	NA	NA	rs7566539-?	rs7566539	0	7566539	intron_variant	TRUE	NR	3e-6	5.522878745280337	(adjusted for dose, GFR & AST)	7.171	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	7.171	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	16q23.2	16	79311795	WWOX, MAF	RNA5SP431 - NA	ENSG00000222244	NA	NA	47222	NA	rs9934640-?	rs9934640	0	9934640	regulatory_region_variant	TRUE	NR	5e-6	5.301029995663981	(adjusted for dose, GFR & AST)	8.074	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	8.074	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Paclitaxel disposition in epithelial ovarian cancer	66 European ancestry cases, 14 Asian ancestry cases	NA	3q26.1	3	166315136	ZBBX, BCHE	NA	NA	NA	NA	NA	NA	rs9283636-?	rs9283636	0	9283636	intergenic_variant	TRUE	NR	5e-7	6.301029995663981	(adjusted for dose, GFR & AST)	3.049	unit increase (EA, Australian cohort)	Illumina [610255]	N	response to paclitaxel	http://purl.obolibrary.org/obo/GO_1901555	GCST005352	Genome-wide genotyping array	NA	3.049	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	2q35	2	217010416	DIRC3, TNP1	NA	NA	NA	NA	NA	NA	rs12165173-?	rs12165173	0	12165173	TF_binding_site_variant	TRUE	NR	5e-6	5.301029995663981	(adjusted for dose, GFR & AST)	1.06	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	10q22.1	10	69910197	COL13A1	COL13A1	NA	NA	ENSG00000197467	NA	NA	rs12412836-?	rs12412836	0	12412836	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(adjusted for dose, GFR & AST)	0.75	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	10q23.1	10	85041429	FAM190B, LOC100507470	NA	NA	NA	NA	NA	NA	rs12571637-?	rs12571637	0	12571637	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	(adjusted for dose, GFR & AST)	1.59	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	14q32.2	14	96778118	PAPOLA, VRK1	LINC02299	NA	NA	ENSG00000258979	NA	NA	rs17280534-?	rs17280534	0	17280534	intron_variant	FALSE	NR	6e-6	5.221848749616356	(adjusted for dose, GFR & AST)	1.49	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	7q36.1	7	151487834	RHEB	RHEB	NA	NA	ENSG00000106615	NA	NA	rs17635967-?	rs17635967	0	17635967	intron_variant	FALSE	NR	6e-6	5.221848749616356	(adjusted for dose, GFR & AST)	1.49	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	6q21	6	105789630	PREP, PRDM1	NA	NA	NA	NA	NA	NA	rs2202766-?	rs2202766	0	2202766	intron_variant	TRUE	NR	7e-6	5.154901959985743	(adjusted for dose, GFR & AST)	1.47	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	15q14	15	38490292	RASGRP1	RASGRP1	NA	NA	ENSG00000172575	NA	NA	rs4313770-?	rs4313770	0	4313770	3_prime_UTR_variant	FALSE	NR	6e-6	5.221848749616356	(adjusted for dose, GFR & AST)	1.49	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	4p15.2	4	27184810	STIM2, MIR4275	NA - LINC02261	NA	ENSG00000249699	NA	NA	32669	rs4692174-?	rs4692174	0	4692174	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	(adjusted for dose, GFR & AST)	0.88	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	20q11.23	20	38323940	BPI	BPI	NA	NA	ENSG00000101425	NA	NA	rs5741804-?	rs5741804	0	5741804	missense_variant	FALSE	NR	9e-6	5.045757490560675	(adjusted for dose, GFR & AST)	1.49	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	11q12.2	11	61792563	C11orf10	TMEM258	NA	NA	ENSG00000134825	NA	NA	rs7102974-?	rs7102974	0	7102974	5_prime_UTR_variant	FALSE	NR	6e-6	5.221848749616356	(adjusted for dose, GFR & AST)	1.49	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	18q11.2	18	27347470	RP11-739N10	NA - UBA52P9	NA	ENSG00000244329	NA	NA	7936	rs7230264-?	rs7230264	0	7230264	intron_variant	TRUE	NR	9e-7	6.045757490560675	(adjusted for dose, GFR & AST)	0.65	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	10p12.1	10	25602315	GPR158	GPR158 - GPN3P1	ENSG00000151025	ENSG00000227465	NA	86	45255	rs7909167-?	rs7909167	0	7909167	intergenic_variant	TRUE	NR	6e-6	5.221848749616356	(adjusted for dose, GFR & AST)	1.49	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	10q24.2	10	99850776	ABCC2	ABCC2	NA	NA	ENSG00000023839	NA	NA	rs8187707-?	rs8187707	0	8187707	synonymous_variant	FALSE	NR	5e-6	5.301029995663981	(adjusted for dose, GFR & AST)	1.21	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	21q21.3	21	25631797	MRPL39, JAM2	MRPL39 - JAM2	ENSG00000154719	ENSG00000154721	NA	24280	7461	rs9982086-?	rs9982086	0	9982086	intergenic_variant	TRUE	NR	9e-6	5.045757490560675	(adjusted for dose, GFR & AST)	1.06	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	13q33.3	13	107290084	FAM155A	FAM155A	NA	NA	ENSG00000204442	NA	NA	rs9558996-?	rs9558996	0	9558996	intron_variant	FALSE	NR	5e-6	5.301029995663981	NA	1.285	unit increase (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	3p14.3	3	55376983	CACNA2D3, WNT5A	LINC02030 - WNT5A	ENSG00000240708	ENSG00000114251	NA	76245	88732	rs11130471-?	rs11130471	0	11130471	intergenic_variant	TRUE	NR	9e-6	5.045757490560675	NA	1.641	unit decrease (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	4q31.21	4	145811502	ZNF827	ZNF827	NA	NA	ENSG00000151612	NA	NA	rs17806780-?	rs17806780	0	17806780	intron_variant	FALSE	NR	9e-6	5.045757490560675	NA	1.484	unit increase (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-03-05	29367611	Gao B	2018-01-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29367611	Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.	Carboplatin disposition in epthelial ovarian cancer	42 European ancestry cases, 14 Asian ancestry cases	NA	5q31.2	5	138109311	WNT8A, NME5	WNT8A - NME5	ENSG00000061492	ENSG00000112981	NA	16946	5864	rs12516561-?	rs12516561	0	12516561	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	NA	1.671	unit increase (EA)	Illumina [610255]	N	response to carboplatin	http://purl.obolibrary.org/obo/GO_0097328	GCST005351	Genome-wide genotyping array	NA	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	4q12	4	55526646	NR	CLOCK	NA	NA	ENSG00000134852	NA	NA	rs13132420-A	rs13132420	0	13132420	intron_variant	FALSE	0.326424356057664	2e-8	7.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.326424356057664	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	4q28.1	4	123145793	NR	SPATA5	NA	NA	ENSG00000145375	NA	NA	rs303084-A	rs303084	0	303084	intron_variant	FALSE	0.79545236333131	7e-8	7.154901959985743	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.79545236333131	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	5q11.2	5	56565039	NR	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs3936510-T	rs3936510	0	3936510	intron_variant	FALSE	0.182860400797187	1e-8	8	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.182860400797187	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	5q35.2	5	173921153	NR	CPEB4	NA	NA	ENSG00000113742	NA	NA	rs10516107-A	rs10516107	0	10516107	intron_variant	FALSE	0.326573038451688	2e-10	9.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.326573038451688	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	5q35.3	5	177100576	NR	FGFR4 - NSD1	ENSG00000160867	ENSG00000165671	NA	2432	32449	rs6556301-T	rs6556301	0	6556301	intergenic_variant	TRUE	0.355742327647949	1e-6	6	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.355742327647949	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	6p25.1	6	6738519	NR	LY86 - BTF3P7	ENSG00000112799	ENSG00000219986	NA	83536	56396	rs1294410-T	rs1294410	0	1294410	intron_variant	TRUE	0.366834831644638	1e-15	15	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.366834831644638	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	6p21.32	6	32413959	NR	TSBP1-AS1 - HLA-DRA	ENSG00000225914	ENSG00000234794	NA	6196	25919	rs7759742-A	rs7759742	0	7759742	regulatory_region_variant	TRUE	0.509001212874385	2e-12	11.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.509001212874385	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	6q22.33	6	127131790	NR	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs2745353-T	rs2745353	0	2745353	intron_variant	FALSE	0.513045531553055	4e-39	38.39794000867204	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.513045531553055	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	7p15.2	7	25822019	NR	NA	NA	NA	NA	NA	NA	rs3902751-A	rs3902751	0	3902751	intergenic_variant	TRUE	0.24849096764601	1e-15	15	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.24849096764601	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	7p15.2	7	27184152	NR	HOXA11	NA	NA	ENSG00000005073	NA	NA	rs7801581-T	rs7801581	0	7801581	intron_variant	FALSE	0.245530226279377	2e-10	9.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.245530226279377	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	8q13.3	8	71601993	NR	EYA1 - NA	ENSG00000104313	NA	NA	9968	NA	rs12679556-T	rs12679556	0	12679556	intergenic_variant	TRUE	0.753113548949924	3e-7	6.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.753113548949924	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	9q31.1	9	104964637	NR	ABCA1 - CT70	ENSG00000165029	ENSG00000230013	NA	36482	5956	rs10991433-T	rs10991433	0	10991433	intergenic_variant	TRUE	0.887123614680935	3e-10	9.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.887123614680935	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	12p11.23	12	26318431	NR	SSPN - ITPR2	ENSG00000123096	ENSG00000123104	NA	19141	16921	rs10842707-T	rs10842707	0	10842707	intron_variant	TRUE	0.232379900368638	4e-18	17.397940008672037	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.232379900368638	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	12q13.13	12	53955989	NR	HOXC12	NA	NA	ENSG00000123407	NA	NA	rs10783615-A	rs10783615	0	10783615	intron_variant	FALSE	0.855651556311748	2e-14	13.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.855651556311748	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	12q24.31	12	124022084	NR	RFLNA	NA	NA	ENSG00000178882	NA	NA	rs10773049-T	rs10773049	0	10773049	intron_variant	FALSE	0.600101243742376	7e-14	13.154901959985743	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.600101243742376	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	15q13.3	15	31416060	NR	KLF13, KLF13	NA	NA	ENSG00000275746, ENSG00000169926	NA	NA	rs8042543-T	rs8042543	0	8042543	intron_variant	FALSE	0.212439614225287	2e-7	6.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.212439614225287	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	15q21.3	15	56236608	NR	RFX7	NA	NA	ENSG00000181827	NA	NA	rs12595496-A	rs12595496	0	12595496	intron_variant	FALSE	0.875928267939582	2e-7	6.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.875928267939582	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	15q22.31	15	66740813	NR	SMAD6	NA	NA	ENSG00000137834	NA	NA	rs1440372-T	rs1440372	0	1440372	non_coding_transcript_exon_variant	FALSE	0.294481057263378	3e-8	7.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.294481057263378	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	16q23.2	16	81501185	NR	CMIP	NA	NA	ENSG00000153815	NA	NA	rs2925979-T	rs2925979	0	2925979	intron_variant	FALSE	0.305441971387991	2e-8	7.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.305441971387991	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	17p11.2	17	17516885	NR	PEMT	NA	NA	ENSG00000133027	NA	NA	rs4646404-A	rs4646404	0	4646404	intron_variant	FALSE	0.34295575089661	2e-10	9.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.34295575089661	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	19p13.11	19	18278325	NR	IQCN - JUND	ENSG00000130518	ENSG00000130522	NA	3816	1369	rs12608504-A	rs12608504	0	12608504	regulatory_region_variant	TRUE	0.357006954395047	5e-7	6.301029995663981	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.357006954395047	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	19q13.11	19	33395448	NR	PEPD	NA	NA	ENSG00000124299	NA	NA	rs7258031-T	rs7258031	0	7258031	intron_variant	FALSE	0.339355889807184	3e-12	11.522878745280337	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.339355889807184	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	20p12.3	20	6642727	NR	NA - LINC01713	NA	ENSG00000228482	NA	NA	88353	rs979012-T	rs979012	0	979012	intergenic_variant	TRUE	0.344993542700339	2e-12	11.698970004336019	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.344993542700339	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	20q11.22	20	35385145	NR	UQCC1	NA	NA	ENSG00000101019	NA	NA	rs4911180-A	rs4911180	0	4911180	intron_variant	FALSE	0.603048781484029	4e-10	9.397940008672037	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.603048781484029	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	20q13.12	20	46884796	NR	RN7SKP33 - EYA2	ENSG00000222874	ENSG00000064655	NA	25124	9828	rs1984076-A	rs1984076	0	1984076	intergenic_variant	TRUE	0.416832342694734	6e-11	10.221848749616356	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.416832342694734	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	3p14.1	3	64716599	ADAMTS9, MIR548A2, PRICKLE2, ADAMTS9-AS2	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs4616635-C	rs4616635	0	4616635	intron_variant	FALSE	0.72049	1e-16	16	NA	0.0503	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.72049	NA	0.0503
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	3q22.1	3	129620772	PLXND1, RAB43, COPG1, RPL32P3, RHO, TMCC1, TRH, ALG1L2, H1FX, EFCAB12, H1FOO, LOC100507032, FAM86HP, ISY1, C3orf37, MBD4, CNBP, IFT122, SNORA7B, ISY1-RAB43, H1FX-AS1	PLXND1 - TMCC1	ENSG00000004399	ENSG00000172765	NA	14096	27020	rs2811434-T	rs2811434	0	2811434	intergenic_variant	TRUE	0.7924	2e-7	6.698970004336019	NA	0.0488	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.7924	NA	0.0488
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	6q22.33	6	127062715	RSPO3, RNF146, ECHDC1, KIAA0408, SOGA3	NA - RSPO3	NA	ENSG00000146374	NA	NA	55956	rs1936811-T	rs1936811	0	1936811	intron_variant	TRUE	0.6104	2e-15	14.698970004336019	NA	0.0439	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.6104	NA	0.0439
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	12p11.23	12	26308212	MIR4302, ITPR2, LOC100506451, RASSF8, BHLHE41, SSPN	SSPN - ITPR2	ENSG00000123096	ENSG00000123104	NA	8922	27140	rs10743579-A	rs10743579	0	10743579	intron_variant	TRUE	0.246	4e-14	13.397940008672037	NA	0.0461	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.246	NA	0.0461
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	7p15.2	7	25832313	NFE2L3, RNU6-16, MIR148A, HNRNPA2B1, CBX3, SNX10	NA	NA	NA	NA	NA	NA	rs6958350-T	rs6958350	0	6958350	regulatory_region_variant	TRUE	0.250023	8e-14	13.096910013008056	NA	0.0329	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.250023	NA	0.0329
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	12q13.13	12	53948900	HOXC13, PCBP2, MAP3K12, TARBP2, NPFF, ATF7, LOC100652999, ATP5G2, CALCOCO1, HOXC-AS5, HOXC12, HOTAIR, HOXC11, HOXC10, MIR196A2, HOXC9, HOXC8, HOXC6, HOXC5, HOXC4, MIR615, FLJ12825, LOC100240735, LOC100240734, LOC400043, SMUG1	HOXC13 - HOXC12	ENSG00000123364	ENSG00000123407	NA	2356	6003	rs1443512-A	rs1443512	0	1443512	regulatory_region_variant	TRUE	0.23638	4e-13	12.397940008672037	NA	0.038	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.23638	NA	0.038
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	8p21.2	8	23745811	NKX2-6, STC1, NKX3-1, CHMP7, R3HCC1, LOXL2, LOC100507156, SLC25A37	NKX2-6 - STC1	ENSG00000180053	ENSG00000159167	NA	39055	96118	rs7830933-A	rs7830933	0	7830933	intron_variant	TRUE	0.766227	8e-7	6.096910013008056	NA	0.0364	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.766227	NA	0.0364
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	12q24.31	12	123934515	CCDC92, ZNF664, DNAH10, RILPL2, SNRNP35, RILPL1, MIR3908, TMED2, DDX55, EIF2B1, GTF2H3, TCTN2, ATP6V0A2, ZNF664-FAM101A, FAM101A, NCOR2	DNAH10OS, DNAH10, CCDC92	NA	NA	ENSG00000250091, ENSG00000197653, ENSG00000119242	NA	NA	rs11057396-A	rs11057396	0	11057396	non_coding_transcript_exon_variant	FALSE	0.67032	6e-8	7.221848749616356	NA	0.0358	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.67032	NA	0.0358
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	6p25.1	6	6734789	LY86, LY86-AS1, F13A1, RREB1	LY86 - BTF3P7	ENSG00000112799	ENSG00000219986	NA	79806	60126	rs1294404-A	rs1294404	0	1294404	intron_variant	TRUE	0.6114	9e-15	14.045757490560675	NA	0.035	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.6114	NA	0.035
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	5q11.2	5	56566067	MAP3K1, ANKRD55, SETD9, MIER3	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs9687846-A	rs9687846	0	9687846	intron_variant	FALSE	0.1872	9e-6	5.045757490560675	NA	0.0257	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.1872	NA	0.0257
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	20q13.12	20	46909795	EYA2, ZNF663, SLC13A3, MKRN7P, ZNF334, TP53RK, SLC2A10, OCSTAMP, MIR3616, ZMYND8, LOC100131496	EYA2	NA	NA	ENSG00000064655	NA	NA	rs6018158-T	rs6018158	0	6018158	intron_variant	FALSE	0.407	4e-10	9.397940008672037	NA	0.0303	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.407	NA	0.0303
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	8q13.3	8	71554089	EYA1, MSC, RNU6-83, LOC100132891, TRPA1	EYA1	NA	NA	ENSG00000104313	NA	NA	rs745578-A	rs745578	0	745578	intron_variant	FALSE	0.243701	3e-7	6.522878745280337	NA	0.0298	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.243701	NA	0.0298
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	5q23.1	5	119393591	TNFAIP8, DTWD2, MIR1244-1, MIR1244-3, MIR1244-2, DMXL1, HSD17B4, FAM170A	TNFAIP8	NA	NA	ENSG00000145779	NA	NA	rs1045241-C	rs1045241	0	1045241	3_prime_UTR_variant	FALSE	0.71	2e-6	5.698970004336019	NA	0.0312	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.71	NA	0.0312
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	14q32.11	14	91080792	RPS6KA5, C14orf159, TTC7B, SNORA11B, GPR68, CCDC88C, SMEK1, CATSPERB	DGLUCY	NA	NA	ENSG00000133943	NA	NA	rs7492628-G	rs7492628	0	7492628	intron_variant	FALSE	0.3018	7e-7	6.154901959985743	NA	0.0292	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.3018	NA	0.0292
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	3p25.2	3	12447843	PPARG, TSEN2, RAF1, TMEM40, IQSEC1, SYN2, TIMP4, LOC100129480, CAND2, MKRN2, RPL32, SNORA7A	PPARG - TSEN2	ENSG00000132170	ENSG00000154743	NA	13487	36578	rs17819328-G	rs17819328	0	17819328	intergenic_variant	TRUE	0.43114	1e-7	7	NA	0.0288	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.43114	NA	0.0288
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	1q24.2	1	170410586	GORAB, PRRX1, LOC284688, METTL11B, KIFAP3, MIR3119-1, MIR3119-2	HAUS4P1 - GORAB-AS1	ENSG00000226967	ENSG00000231407	NA	40219	49867	rs4656767-A	rs4656767	0	4656767	regulatory_region_variant	TRUE	0.7093	5e-7	6.301029995663981	NA	0.0259	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.7093	NA	0.0259
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	2p14	2	66545830	MEIS1-AS3, MIR4778, MEIS1	MEIS1	NA	NA	ENSG00000143995	NA	NA	rs13029520-T	rs13029520	0	13029520	intron_variant	FALSE	0.3973	6e-7	6.221848749616356	NA	0.019	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.3973	NA	0.019
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	4q22.1	4	88791970	FAM13A, HERC6, HERC5, PIGY, PYURF, HERC3, NAP1L5, FAM13A-AS1, TIGD2, GPRIN3	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs9991328-T	rs9991328	0	9991328	intron_variant	FALSE	0.485313	5e-8	7.301029995663981	NA	0.0229	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.485313	NA	0.0229
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	10q24.32	10	102727686	ELOVL3, PITX3, GBF1, NFKB2, PSD, C10orf95, FBXL15, CUEDC2, MIR146B, LOC100505761, SFXN2, TMEM180, ACTR1A, SUFU, TRIM8, ARL3, WBP1L, CYP17A1, AS3MT, C10orf32, C10orf32-AS3Mt, CNNM2, NT5C2	SFXN2	NA	NA	ENSG00000156398	NA	NA	rs7917772-A	rs7917772	0	7917772	3_prime_UTR_variant	FALSE	0.617	8e-6	5.096910013008056	NA	0.0269	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.617	NA	0.0269
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	11q12.3	11	62638690	GANAB, INCENP, SCGB1D1, SCGB2A1, SCGB1D2, SCGB2A2, SCGB1D4, ASRGL1, SCGB1A1, AHNAK, EEF1G, MIR3654, TUT1, EML3, ROM1, B3GAT3, INTS5, C11orf48, MTA2, BSCL2, C11orf83, UBXN1, LRRN4CL, GNG3	GANAB	NA	NA	ENSG00000089597	NA	NA	rs2956993-G	rs2956993	0	2956993	intron_variant	FALSE	0.38	2e-6	5.698970004336019	NA	0.024	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.38	NA	0.024
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	17q24.3	17	70457204	KCNJ16, KCNJ2, KCNJ2-AS1	NA	NA	NA	NA	NA	NA	rs8066985-A	rs8066985	0	8066985	intergenic_variant	TRUE	0.5085	9e-7	6.045757490560675	NA	0.0252	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.5085	NA	0.0252
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	5q35.3	5	177299634	NSD1, UNC5A, HK3, UIMC1, ZNF346, FGFR4, RAB24, PREUD1, MXD3, LMAN2, SLC34A1, PRR7-AS1, PFN3, RGS14, F12, GRK6, PRR7, DDX41, PDLIM7, DBN1, DOK3, FAM193B, TMED9, B4GALT7, LOC202181	NSD1	NA	NA	ENSG00000165671	NA	NA	rs3088050-A	rs3088050	0	3088050	3_prime_UTR_variant	FALSE	0.21	1e-7	7	NA	0.0056	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.21	NA	0.0056
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	20q11.22	20	35157873	EDEM2, PIGU, TP53INP2, NCOA6, HMGB3P1, GGT7, ACSS2, GSS, MYH7B, MIR499A, MIR499B, TRPC4AP, PROCR, EIF6, MMP24, FAM83C, UQCC, GDF5, CEP250, ERGIC3, C20orf173, SPAG4, FER1L4, CPNE1	EDEM2 - PROCR	ENSG00000088298	ENSG00000101000	NA	10537	14199	rs6088735-C	rs6088735	0	6088735	intergenic_variant	TRUE	0.7665	8e-8	7.096910013008056	NA	0.0078	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.7665	NA	0.0078
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	2p14	2	66555335	MEIS1-AS3, MIR4778	MEIS1	NA	NA	ENSG00000143995	NA	NA	rs2300481-T	rs2300481	0	2300481	intron_variant	FALSE	0.39538080480749	1e-7	7	NA	0.02104353	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.39538080480749	NA	0.02104353
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI	up to 113,720 European ancestry men, up to 138,655 European ancestry women	NA	2p14	2	67522542	LOC644838	NA - LINC02831	NA	ENSG00000224173	NA	NA	39525	rs2860517-T	rs2860517	0	2860517	intergenic_variant	TRUE	0.404881605944713	8e-9	8.096910013008056	NA	0.021623781	units increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio	http://www.ebi.ac.uk/efo/EFO_0007788	GCST005956	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.404881605944713	NA	0.021623781
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p21.1	7	20391962	ITGB8	ITGB8	NA	NA	ENSG00000105855	NA	NA	rs10231365-T	rs10231365	0	10231365	intron_variant	FALSE	0.5025	9e-9	8.045757490560675	(EA)	0.024	[0.016-0.032] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5025	NA	0.024
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	25831489	UBA52P1	NA	NA	NA	NA	NA	NA	rs1055144-T	rs1055144	0	1055144	non_coding_transcript_exon_variant	TRUE	0.1983	5e-15	14.301029995663981	(EA)	0.0368	[0.028-0.046] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.1983	NA	0.0368
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	27184152	HOXA11	HOXA11	NA	NA	ENSG00000005073	NA	NA	rs7801581-T	rs7801581	0	7801581	intron_variant	FALSE	0.2445	2e-8	7.698970004336019	(EA)	0.0253	[0.016-0.034] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2445	NA	0.0253
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.1	7	28150327	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs1708299-A	rs1708299	0	1708299	intron_variant	FALSE	0.2994	6e-14	13.221848749616356	(EA)	0.03	[0.022-0.038] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2994	NA	0.03
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	8p21.2	8	23745811	NKX2-6	NKX2-6 - STC1	ENSG00000180053	ENSG00000159167	NA	39055	96118	rs7830933-A	rs7830933	0	7830933	intron_variant	TRUE	0.7625	1e-6	6	(EA)	0.0211	[0.012-0.03] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7625	NA	0.0211
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9q22.32	9	95648123	PTCH1	NA	NA	NA	NA	NA	NA	rs10990303-T	rs10990303	0	10990303	intergenic_variant	TRUE	0.2238	7e-11	10.154901959985743	(EA)	0.0299	[0.021-0.039] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2238	NA	0.0299
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	9q31.2	9	106163165	TMEM38B	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs7020666-C	rs7020666	0	7020666	intron_variant	FALSE	0.7075	1e-7	7	(EA)	0.0246	[0.016-0.034] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7075	NA	0.0246
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	10q22.3	10	79147390	ZMIZ1	ZMIZ1	NA	NA	ENSG00000108175	NA	NA	rs780159-G	rs780159	0	780159	intron_variant	FALSE	0.5817	6e-9	8.221848749616356	(EA)	0.0223	[0.015-0.03] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5817	NA	0.0223
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	11p15.1	11	17294482	NUCB2	NUCB2	NA	NA	ENSG00000070081	NA	NA	rs1330-T	rs1330	0	1330	intron_variant	FALSE	0.3426	4e-8	7.3979400086720375	(EA)	0.0216	[0.014-0.029] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3426	NA	0.0216
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	11q13.5	11	75565133	SERPINH1	SERPINH1	NA	NA	ENSG00000149257	NA	NA	rs606452-A	rs606452	0	606452	intron_variant	FALSE	0.1447	6e-9	8.221848749616356	(EA)	0.0315	[0.021-0.042] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.1447	NA	0.0315
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12p12.1	12	26290097	ITPR2-SSPN	SSPN	NA	NA	ENSG00000123096	NA	NA	rs4963975-A	rs4963975	0	4963975	intron_variant	FALSE	0.2541	3e-9	8.522878745280337	(EA)	0.0254	[0.017-0.034] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.2541	NA	0.0254
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12p11.22	12	28318386	CCDC91	CCDC91	NA	NA	ENSG00000123106	NA	NA	rs10843151-G	rs10843151	0	10843151	intron_variant	FALSE	0.6889000000000001	1e-10	10	(EA)	0.0312	[0.022-0.041] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6889000000000001	NA	0.0312
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q13.13	12	54025136	HOXC4, HOXC5, HOXC6	HOXC6, HOXC4	NA	NA	ENSG00000197757, ENSG00000198353	NA	NA	rs754133-A	rs754133	0	754133	intron_variant	FALSE	0.3607	2e-14	13.698970004336019	(EA)	0.0295	[0.022-0.037] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.3607	NA	0.0295
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	12q24.31	12	123935181	DNAH10	DNAH10, CCDC92	NA	NA	ENSG00000197653, ENSG00000119242	NA	NA	rs11057397-C	rs11057397	0	11057397	intron_variant	FALSE	0.6614	9e-9	8.045757490560675	(EA)	0.0224	[0.015-0.03] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6614	NA	0.0224
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	14q32.12	14	91993614	TRIP11	TRIP11	NA	NA	ENSG00000100815	NA	NA	rs8007661-C	rs8007661	0	8007661	intron_variant	FALSE	0.6098	2e-8	7.698970004336019	(EA)	0.0239	[0.016-0.032] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6098	NA	0.0239
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q24.1	15	73936469	LOXL1	LOXL1	NA	NA	ENSG00000129038	NA	NA	rs4886782-G	rs4886782	0	4886782	intron_variant	FALSE	0.6194	4e-10	9.397940008672037	(EA)	0.025	[0.017-0.033] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6194	NA	0.025
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	83845538	ADAMTSL3	ADAMTSL3	NA	NA	ENSG00000156218	NA	NA	rs7162542-G	rs7162542	0	7162542	intron_variant	FALSE	0.5582	9e-27	26.045757490560675	(EA)	0.0401	[0.033-0.047] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5582	NA	0.0401
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q25.2	15	84597563	ZSCAN2	LINC00933 - ZSCAN2	ENSG00000259728	ENSG00000176371	NA	17388	3423	rs7176527-C	rs7176527	0	7176527	intergenic_variant	TRUE	0.8071	6e-9	8.221848749616356	(EA)	0.0317	[0.021-0.042] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.8071	NA	0.0317
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	15q26.1	15	88871064	ACAN	ACAN	NA	NA	ENSG00000157766	NA	NA	rs1879529-G	rs1879529	0	1879529	intron_variant	FALSE	0.7214	2e-9	8.698970004336019	(EA)	0.0256	[0.017-0.034] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7214	NA	0.0256
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17p13.3	17	560603	VPS53	VPS53, VPS53	NA	NA	ENSG00000141252, ENSG00000283883	NA	NA	rs741677-A	rs741677	0	741677	intron_variant	FALSE	0.5798	2e-8	7.698970004336019	(EA)	0.0243	[0.016-0.033] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5798	NA	0.0243
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	17q11.2	17	30837005	ATAD5	ATAD5	NA	NA	ENSG00000176208	NA	NA	rs3764419-C	rs3764419	0	3764419	intron_variant	FALSE	0.6093	5e-8	7.301029995663981	(EA)	0.021	[0.013-0.029] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6093	NA	0.021
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	2p25.3	2	3600596	COLEC11, AC010907.2	COLEC11	NA	NA	ENSG00000118004	NA	NA	rs7588285-C	rs7588285	0	7588285	intron_variant	FALSE	0.2053213	3e-37	36.52287874528034	(Interleukin-19)	0.6794	[0.58-0.78] unit increase	Affymetrix [509946]	N	interleukin 19 measurement	http://www.ebi.ac.uk/efo/EFO_0008180	GCST004365	Genome-wide genotyping array	0.2053213	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4p15.32	4	15645318	BST1, FBXL5, CC2D2A, FAM200B	FBXL5	NA	NA	ENSG00000118564	NA	NA	rs7657257-A	rs7657257	0	7657257	intron_variant	FALSE	0.03560682	2e-26	25.69897000433602	(ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2)	1.206	[0.99-1.42] unit decrease	Affymetrix [509946]	N	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 measurement	http://www.ebi.ac.uk/efo/EFO_0008014	GCST004365	Genome-wide genotyping array	0.03560682	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	5q11.2	5	55970684	IL6ST, CTD-2031P19.5, AC008914.1, CTD-2031P19.4, FLJ31104, snoU13	IL6ST	NA	NA	ENSG00000134352	NA	NA	rs7730934-A	rs7730934	0	7730934	intron_variant	FALSE	0.1082578	3e-15	14.522878745280337	(Interleukin-6 receptor subunit beta)	0.5605	[0.42-0.7] unit increase	Affymetrix [509946]	N	interleukin 6 receptor subunit beta measurement	http://www.ebi.ac.uk/efo/EFO_0008188	GCST004365	Genome-wide genotyping array	0.1082578	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	13q34	13	113127628	F10, F10-AS1, KARSP2	F10	NA	NA	ENSG00000126218	NA	NA	rs776905-C	rs776905	0	776905	intron_variant	FALSE	0.1128385	9e-65	64.04575749056067	(Coagulation Factor VII)	1.104	[0.99-1.22] unit decrease	Affymetrix [509946]	N	factor VII measurement	http://www.ebi.ac.uk/efo/EFO_0004619	GCST004365	Genome-wide genotyping array	0.1128385	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19p13.3	19	5844526	FUT3, AC024592.9, FUT6	FUT3	NA	NA	ENSG00000171124	NA	NA	rs778986-A	rs778986	0	778986	missense_variant	FALSE	0.2043173	9e-73	72.04575749056067	(Galactoside 3(4)-L-fucosyltransferase)	0.9298	[0.84-1.02] unit decrease	Affymetrix [509946]	N	galactoside 34-L-fucosyltransferase measurement	http://www.ebi.ac.uk/efo/EFO_0008136	GCST004365	Genome-wide genotyping array	0.2043173	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	9q34.2	9	133253159	ABO	ABO, ABO	NA	NA	ENSG00000175164, ENSG00000281879	NA	NA	rs7857390-A	rs7857390	0	7857390	non_coding_transcript_exon_variant	FALSE	0.3845382	6e-11	10.221848749616356	(Tyrosine-protein kinase receptor Tie-1, soluble)	0.2949	[0.21-0.38] unit decrease	Affymetrix [509946]	N	tyrosine-protein kinase receptor Tie-1, soluble measurement	http://www.ebi.ac.uk/efo/EFO_0008312	GCST004365	Genome-wide genotyping array	0.3845382	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	16q22.2	16	71438801	AC010547.9, RP11-510M2.4, RP11-510M2.8, ZNF19	TLE7	NA	NA	ENSG00000260734	NA	NA	rs8049040-G	rs8049040	0	8049040	intron_variant	FALSE	0.4160804	6e-15	14.221848749616356	(Haptoglobin)	0.3541	[0.27-0.44] unit increase	Affymetrix [509946]	N	haptoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004640	GCST004365	Genome-wide genotyping array	0.4160804	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6p21.33	6	31697675	ABHD16A, XXbac-BPG32J3.20, MIR4646	ABHD16A, ABHD16A, ABHD16A, ABHD16A, ABHD16A, ABHD16A, ABHD16A	NA	NA	ENSG00000224552, ENSG00000204427, ENSG00000235676, ENSG00000206403, ENSG00000231488, ENSG00000236063, ENSG00000230475	NA	NA	rs805273-A	rs805273	0	805273	intron_variant	FALSE	0.06820461	5e-16	15.301029995663981	(Complement C4)	0.699	[0.53-0.87] unit increase	Affymetrix [509946]	N	complement C4 measurement	http://www.ebi.ac.uk/efo/EFO_0004984	GCST004365	Genome-wide genotyping array	0.06820461	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19q13.41	19	51043595	CTC-518B2.9, KLK12, CTC-518B2.10	KLK12 - KLK13	ENSG00000186474	ENSG00000167759	NA	8365	12031	rs8103941-G	rs8103941	0	8103941	intergenic_variant	TRUE	0.2454819	5e-50	49.30102999566398	(Kallikrein-12)	0.7388	[0.65-0.83] unit increase	Affymetrix [509946]	N	kallikrein-12 measurement	http://www.ebi.ac.uk/efo/EFO_0008194	GCST004365	Genome-wide genotyping array	0.2454819	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19q13.2	19	38333941	YIF1B, C19orf33, CATSPERG, CTB-102L5.4, KCNK6, AC005625.1	KCNK6 - CATSPERG	ENSG00000099337	ENSG00000099338	NA	1865	1834	rs8112211-T	rs8112211	0	8112211	intergenic_variant	TRUE	0.2547643	1e-88	88	(Kunitz-type protease inhibitor 2)	0.9467	[0.86-1.03] unit decrease	Affymetrix [509946]	N	Kunitz-type protease inhibitor 2 measurement	http://www.ebi.ac.uk/efo/EFO_0008200	GCST004365	Genome-wide genotyping array	0.2547643	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	9q34.2	9	133257486	ABO	ABO, ABO	NA	NA	ENSG00000175164, ENSG00000281879	NA	NA	rs8176720-C	rs8176720	0	8176720	synonymous_variant	FALSE	0.3440321	7e-10	9.154901959985743	(Insulin receptor)	0.2796	[0.19-0.37] unit increase	Affymetrix [509946]	N	insulin receptor measurement	http://www.ebi.ac.uk/efo/EFO_0008160	GCST004365	Genome-wide genotyping array	0.3440321	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	NA	NA	NA	ABO, Y_RNA, LCN1P2	NA	NA	NA	NA	NA	NA	rs8176749-T	rs8176749	0	8176749	synonymous_variant	TRUE	0.08693467	1e-35	35	(Angiopoietin-1 receptor, soluble)	0.9056	[0.77-1.04] unit increase	Affymetrix [509946]	N	angiopoietin-1 receptor, soluble measurement	http://www.ebi.ac.uk/efo/EFO_0008023	GCST004365	Genome-wide genotyping array	0.08693467	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	NA	NA	NA	ABO, Y_RNA, LCN1P2	NA	NA	NA	NA	NA	NA	rs8176749-T	rs8176749	0	8176749	synonymous_variant	TRUE	0.08693467	6e-53	52.221848749616356	(Cadherin-5)	1.108	[0.97-1.24] unit increase	Affymetrix [509946]	N	cadherin-5 measurement	http://www.ebi.ac.uk/efo/EFO_0008060	GCST004365	Genome-wide genotyping array	0.08693467	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	NA	NA	NA	ABO, Y_RNA, LCN1P2	NA	NA	NA	NA	NA	NA	rs8176749-T	rs8176749	0	8176749	synonymous_variant	TRUE	0.08693467	6e-10	9.221848749616356	(Neurogenic locus notch homolog protein 1)	0.4484	[0.31-0.59] unit increase	Affymetrix [509946]	N	neurogenic locus notch homolog protein 1 measurement	http://www.ebi.ac.uk/efo/EFO_0008246	GCST004365	Genome-wide genotyping array	0.08693467	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	NA	NA	NA	ABO, Y_RNA, LCN1P2	NA	NA	NA	NA	NA	NA	rs8176749-T	rs8176749	0	8176749	synonymous_variant	TRUE	0.08693467	2e-51	50.69897000433602	(Tyrosine-protein kinase receptor Tie-1, soluble)	1.099	[0.96-1.23] unit increase	Affymetrix [509946]	N	tyrosine-protein kinase receptor Tie-1, soluble measurement	http://www.ebi.ac.uk/efo/EFO_0008312	GCST004365	Genome-wide genotyping array	0.08693467	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6p21.32	6	32115523	ATF6B, TNXB	ATF6B, ATF6B, ATF6B, ATF6B	NA	NA	ENSG00000168468, ENSG00000234539, ENSG00000228628, ENSG00000213676	NA	NA	rs8283-G	rs8283	0	8283	3_prime_UTR_variant	FALSE	0.1906439	2e-17	16.69897000433602	(Complement C4)	0.487	[0.38-0.6] unit increase	Affymetrix [509946]	N	complement C4 measurement	http://www.ebi.ac.uk/efo/EFO_0004984	GCST004365	Genome-wide genotyping array	0.1906439	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	NA	NA	NA	TRPC4AP, EDEM2, PROCR, GSS, MYH7B, MIR499A, RNU6-407P, SNORD56, RP11-42O4.2, RNA5SP483, RP4-614O4.12	NA	NA	NA	NA	NA	NA	rs867186-G	rs867186	0	867186	missense_variant	TRUE	0.1183551	5e-38	37.30102999566398	(Vitamin K-dependent protein C)	0.8382	[0.72-0.96] unit increase	Affymetrix [509946]	N	vitamin K-dependent protein C measurement	http://www.ebi.ac.uk/efo/EFO_0008318	GCST004365	Genome-wide genotyping array	0.1183551	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	14q32.13	14	94561385	SERPINA5, SERPINA4	SERPINA12 - SERPINA4	ENSG00000165953	ENSG00000100665	NA	43541	57	rs882732-A	rs882732	0	882732	intergenic_variant	TRUE	0.246988	8e-48	47.096910013008056	(Kallistatin)	0.6674	[0.58-0.75] unit increase	Affymetrix [509946]	N	kallistatin measurement	http://www.ebi.ac.uk/efo/EFO_0008196	GCST004365	Genome-wide genotyping array	0.246988	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	2q22.2	2	143040620	KYNU	KYNU	NA	NA	ENSG00000115919	NA	NA	rs9013-G	rs9013	0	9013	missense_variant	FALSE	0.1579739	1e-81	81	(Kynureninase)	1.045	[0.95-1.14] unit decrease	Affymetrix [509946]	N	kynureninase measurement	http://www.ebi.ac.uk/efo/EFO_0008201	GCST004365	Genome-wide genotyping array	0.1579739	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6p21.33	6	31929442	SKIV2L, C2, XXbac-BPG116M5.17, NELFE, MIR1236, DXO, STK19	C2, C2, C2, C2	NA	NA	ENSG00000166278, ENSG00000231543, ENSG00000235017, ENSG00000206372	NA	NA	rs9283893-A	rs9283893	0	9283893	intron_variant	FALSE	0.0446339	1e-32	32	(Neutrophil collagenase)	1.199	[1.01-1.39] unit increase	Affymetrix [509946]	N	neutrophil collagenase measurement	http://www.ebi.ac.uk/efo/EFO_0008248	GCST004365	Genome-wide genotyping array	0.0446339	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6q25.3	6	160149082	SLC22A1	SLC22A1	NA	NA	ENSG00000175003	NA	NA	rs9295123-A	rs9295123	0	9295123	intron_variant	FALSE	0.4199396	5e-14	13.301029995663981	(Cation-independent mannose-6-phosphate receptor)	0.3313	[0.25-0.42] unit increase	Affymetrix [509946]	N	cation-independent mannose-6-phosphate receptor measurement	http://www.ebi.ac.uk/efo/EFO_0008075	GCST004365	Genome-wide genotyping array	0.4199396	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	16q22.2	16	72110275	DHX38, TXNL4B, PMFBP1	DHX38	NA	NA	ENSG00000140829	NA	NA	rs9302635-C	rs9302635	0	9302635	intron_variant	FALSE	0.1765296	3e-10	9.522878745280337	(Ferritin)	0.3717	[0.26-0.49] unit increase	Affymetrix [509946]	N	ferritin measurement	http://www.ebi.ac.uk/efo/EFO_0004459	GCST004365	Genome-wide genotyping array	0.1765296	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	16q22.2	16	72110275	DHX38, TXNL4B, PMFBP1	DHX38	NA	NA	ENSG00000140829	NA	NA	rs9302635-C	rs9302635	0	9302635	intron_variant	FALSE	0.1765296	6e-54	53.221848749616356	(Haptoglobin)	0.8758	[0.77-0.98] unit increase	Affymetrix [509946]	N	haptoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004640	GCST004365	Genome-wide genotyping array	0.1765296	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19p13.2	19	7723205	CLEC4G	FCER2 - CLEC4G	ENSG00000104921	ENSG00000182566	NA	21059	5753	rs8106657-C	rs8106657	0	8106657	regulatory_region_variant	TRUE	0.2567839	4e-13	12.397940008672037	(EA, CD209 antigen)	0.3616	[0.27-0.46] unit decrease	Affymetrix [509946]	N	CD209 antigen measurement	http://www.ebi.ac.uk/efo/EFO_0008077	GCST004365	Genome-wide genotyping array	0.2567839	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6p21.33	6	31453523	MICA, XXbac-BPG181B23.7, HCP5, Y_RNA, LINC01149, XXbac-BPG181B23.6	LINC01149 - HCP5	ENSG00000230174	ENSG00000230389	NA	6550	9647	rs9469012-A	rs9469012	0	9469012	intron_variant	TRUE	0.1170535	1e-24	24	(MHC class I polypeptide-related sequence A)	0.6944	[0.57-0.82] unit decrease	Affymetrix [509946]	N	MHC class I polypeptide-related sequence A measurement	http://www.ebi.ac.uk/efo/EFO_0008233	GCST004365	Genome-wide genotyping array	0.1170535	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	11q13.2	11	67274496	ADRBK1	GRK2	NA	NA	ENSG00000173020	NA	NA	rs569598265-C	rs569598265	1	57767154	intron_variant	FALSE	0.8004	2e-14	13.698970004336019	NA	0.03502666	[0.026-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.8004	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	11q13.2	11	67463558	CTC-1337H24.2	TMEM134	NA	NA	ENSG00000172663	NA	NA	rs11285778-C	rs11285778	0	11285778	3_prime_UTR_variant	FALSE	0.4371	2e-21	20.69897000433602	NA	0.03386472	[0.027-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.4371	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	11q21	11	95153468	RP11-712B9.2	BUD13P1 - SESN3	ENSG00000270689	ENSG00000149212	NA	8343	12045	rs496321-C	rs496321	0	496321	intron_variant	TRUE	0.6136	1e-11	11	NA	0.02458067	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.6136	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	11q22.3	11	108430128	C11orf65	C11orf65	NA	NA	ENSG00000166323	NA	NA	rs34005627-C	rs34005627	0	34005627	intron_variant	FALSE	0.4135	1e-16	16	NA	0.02996776	[0.023-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.4135	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	11q24.3	11	128069767	intergenic	NA - LINC02725	NA	ENSG00000273415	NA	NA	25991	rs1425869-T	rs1425869	0	1425869	intergenic_variant	TRUE	0.6732	7e-11	10.154901959985743	NA	0.02460883	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.6732	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	12p13.32	12	4222106	intergenic	NA - CCND2-AS1	NA	ENSG00000255920	NA	NA	25875	rs11611397-T	rs11611397	0	11611397	intergenic_variant	TRUE	0.212	6e-55	54.221848749616356	NA	0.0676497	[0.059-0.076] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.212	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	12q13.13	12	52068035	C12orf44	NR4A1 - ATG101	ENSG00000123358	ENSG00000123395	NA	8528	1211	rs10783487-A	rs10783487	0	10783487	intergenic_variant	TRUE	0.1958	4e-12	11.397940008672037	NA	0.03128947	[0.022-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.1958	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	12q13.13	12	53366378	intergenic	SP7 - SP1	ENSG00000170374	ENSG00000185591	NA	21063	13798	rs58123204-G	rs58123204	0	58123204	intergenic_variant	TRUE	0.1532	3e-15	14.522878745280337	NA	0.03859187	[0.029-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.1532	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	12q13.13	12	54292096	RP11-968A15.8	HNRNPA1 - NFE2	ENSG00000135486	ENSG00000123405	NA	5008	15	rs35979828-T	rs35979828	0	35979828	intron_variant	TRUE	0.0705	4e-10	9.397940008672037	NA	0.0431627	[0.03-0.057] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.0705	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	12q21.32	12	88424702	intergenic	TMTC3 - Y_RNA	ENSG00000139324	ENSG00000199964	NA	224815	5740	rs6538148-G	rs6538148	0	6538148	intergenic_variant	TRUE	0.7032	2e-14	13.698970004336019	NA	0.02969466	[0.022-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.7032	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	12q22	12	93364543	RP11-486A14.2	C12orf60 - NUDT4	ENSG00000182993	ENSG00000173598	NA	78457957	13340	rs59883166-AT	rs59883166	0	59883166	intron_variant	TRUE	0.1116	6e-17	16.221848749616356	NA	0.04805726	[0.037-0.059] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.1116	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	12q24.12	12	111409936	SH2B3	SH2B3	NA	NA	ENSG00000111252	NA	NA	rs3803170-G	rs3803170	0	3803170	intron_variant	FALSE	0.2099	4e-9	8.397940008672037	NA	0.02577288	[0.017-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2099	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	12q24.31	12	120713260	UNC119B	UNC119B	NA	NA	ENSG00000175970	NA	NA	rs3833788-C	rs3833788	0	3833788	splice_acceptor_variant	FALSE	0.3891	3e-39	38.52287874528034	NA	0.04751259	[0.04-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.3891	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	12q24.31	12	120920824	RPL12P33	RPL12P33 - HNF1A-AS1	ENSG00000244585	ENSG00000241388	NA	3588	20904	rs371638091-A	rs371638091	0	371638091	intergenic_variant	TRUE	0.3697	6e-10	9.221848749616356	NA	0.02318482	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.3697	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	13q12.3	13	30488053	HMGB1	HMGB1	NA	NA	ENSG00000189403	NA	NA	rs7330209-C	rs7330209	0	7330209	intron_variant	FALSE	0.4492	2e-10	9.698970004336019	NA	0.02281384	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.4492	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	13q14.11	13	40670123	FOXO1	FOXO1 - MIR320D1	ENSG00000150907	ENSG00000211491	NA	3482	57705	rs9532580-C	rs9532580	0	9532580	intergenic_variant	TRUE	0.2615	7e-9	8.154901959985743	NA	0.02357476	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2615	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	13q22.1	13	72993053	PIBF1	PIBF1	NA	NA	ENSG00000083535	NA	NA	rs561619482-A	rs561619482	0	561619482	intron_variant	FALSE	0.0045	6e-11	10.221848749616356	NA	0.1817326	[0.13-0.24] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.0045	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	13q22.2	13	75490523	intergenic	TBC1D4 - COMMD6	ENSG00000136111	ENSG00000188243	NA	8354	34691	rs9565170-C	rs9565170	0	9565170	intergenic_variant	TRUE	0.1002	1e-21	21	NA	0.05687172	[0.045-0.069] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.1002	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	13q33.3	13	108766811	MYO16	MYO16	NA	NA	ENSG00000041515	NA	NA	rs9521017-T	rs9521017	0	9521017	intron_variant	FALSE	0.3647	3e-12	11.522878745280337	NA	0.02575249	[0.019-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.3647	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	13q34	13	109749719	IRS2	LINC00676 - IRS2	ENSG00000234854	ENSG00000185950	NA	19712	2976	rs61358232-T	rs61358232	0	61358232	intergenic_variant	TRUE	0.3241	4e-13	12.397940008672037	NA	0.02754935	[0.02-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.3241	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	13q34	13	113198721	PCID2	PCID2	NA	NA	ENSG00000126226	NA	NA	rs61966459-G	rs61966459	0	61966459	intron_variant	FALSE	0.3159	3e-14	13.522878745280337	NA	0.02900448	[0.022-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.3159	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	14q11.2	14	23030112	PSMB5	PSMB5	NA	NA	ENSG00000100804	NA	NA	rs113525195-A	rs113525195	0	113525195	intron_variant	FALSE	0.2767	1e-15	15	NA	0.03166069	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2767	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	14q13.3	14	37218925	MIPOL1	MIPOL1	NA	NA	ENSG00000151338	NA	NA	rs150658949-C	rs150658949	0	150658949	intron_variant	FALSE	0.2879	8e-15	14.096910013008056	NA	0.03036032	[0.023-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.2879	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	14q23.1	14	58261180	C14orf37, PSMA3	PSMA3, ARMH4	NA	NA	ENSG00000100567, ENSG00000139971	NA	NA	rs11402145-AT	rs11402145	0	11402145	intron_variant	FALSE	0.7004	3e-11	10.522878745280337	NA	0.02637997	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.7004	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Mean corpuscular hemoglobin	172,332 European ancestry individuals	NA	14q23.3	14	65020976	FNTB, CHURC1-FNTB, MAX	FNTB, CHURC1-FNTB, MAX	NA	NA	ENSG00000257365, ENSG00000125954, ENSG00000125952	NA	NA	rs11627485-C	rs11627485	0	11627485	intron_variant	FALSE	0.4469	2e-74	73.69897000433602	NA	0.06525411	[0.058-0.072] unit increase	Affymetrix [~ 2500000] (imputed)	N	mean corpuscular hemoglobin	http://www.ebi.ac.uk/efo/EFO_0004527	GCST004630	Genome-wide genotyping array	0.4469	NA	NA
2018-08-17	29107063	Yashin AI	2017-10-26	Exp Gerontol	www.ncbi.nlm.nih.gov/pubmed/29107063	Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses.	Alzheimer's disease	at least 3,569 European, Black, and unknown ancestry cases, at least 19,085 European, Black, and unknown ancestry controls	NA	19q13.32	19	44892362	TOMM40	TOMM40	NA	NA	ENSG00000130204	NA	NA	rs2075650-?	rs2075650	0	2075650	intron_variant	FALSE	NA	2e-7	6.698970004336019	NA	1.5	[NR]	Illumina [up to 1329158]	N	Alzheimer's disease	http://www.ebi.ac.uk/efo/EFO_0000249	GCST006121	Genome-wide genotyping array	NA	1.5	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	2q32.1	2	187218396	NR	RN7SKP42 - RNU6-989P	ENSG00000222845	ENSG00000199626	NA	95535	52302	rs13424740-T	rs13424740	0	13424740	intron_variant	TRUE	0.529034400293698	1e-10	10	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.529034400293698	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50	NA	3p25.2	3	12292917	NR	PPARG	NA	NA	ENSG00000132170	NA	NA	rs2972164-T	rs2972164	0	2972164	intron_variant	FALSE	0.460702141477614	8e-7	6.096910013008056	NA	NA	NA	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007	GCST005962	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.460702141477614	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q16.3	6	104916546	HACE1	LIN28B-AS1	NA	NA	ENSG00000203809	NA	NA	rs11156429-T	rs11156429	0	11156429	intron_variant	FALSE	0.4566	2e-15	14.698970004336019	(EA)	0.0297	[0.022-0.037] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.4566	NA	0.0297
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q22.33	6	127147043	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs2503111-A	rs2503111	0	2503111	intron_variant	FALSE	0.5446	2e-10	9.698970004336019	(EA)	0.0254	[0.018-0.033] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.5446	NA	0.0254
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q24.2	6	142382740	GPR126	ADGRG6	NA	NA	ENSG00000112414	NA	NA	rs4896582-G	rs4896582	0	4896582	intron_variant	FALSE	0.6960999999999999	1e-12	12	(EA)	0.0288	[0.021-0.037] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.6960999999999999	NA	0.0288
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist circumference adjusted for body mass index	2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p22.3	7	2762169	AMZ1	GNA12, AMZ1	NA	NA	ENSG00000146535, ENSG00000174945	NA	NA	rs798489-C	rs798489	0	798489	splice_donor_variant	FALSE	0.7105	9e-8	7.045757490560675	(EA)	0.0222	[0.014-0.03] cm increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist circumference	http://www.ebi.ac.uk/efo/EFO_0007789	GCST004562	Genome-wide genotyping array	0.7105	NA	0.0222
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p34.3	1	39570014	NR	PABPC4, PABPC4-AS1	NA	NA	ENSG00000090621, ENSG00000228060	NA	NA	rs17513135-C	rs17513135	0	17513135	intron_variant	FALSE	NR	2e-20	19.69897000433602	NA	0.039	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.039
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109264661	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs6657811-A	rs6657811	0	6657811	intron_variant	FALSE	0.88	2e-10	9.698970004336019	(EA)	0.039	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.88	NA	0.039
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109264661	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs6657811-A	rs6657811	0	6657811	intron_variant	FALSE	NR	4e-10	9.397940008672037	NA	0.037	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.037
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109274570	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs7528419-A	rs7528419	0	7528419	3_prime_UTR_variant	FALSE	0.781	2e-15	14.698970004336019	(EA)	0.038	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.781	NA	0.038
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109274570	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs7528419-A	rs7528419	0	7528419	3_prime_UTR_variant	FALSE	NR	6e-15	14.221848749616356	NA	0.034	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.034
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109274968	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs12740374-G	rs12740374	0	12740374	3_prime_UTR_variant	FALSE	0.782	3e-15	14.522878745280337	(EA)	0.037	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.782	NA	0.037
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109274968	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs12740374-G	rs12740374	0	12740374	3_prime_UTR_variant	FALSE	NR	5e-15	14.301029995663981	NA	0.034	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.034
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109275216	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs660240-T	rs660240	0	660240	3_prime_UTR_variant	FALSE	0.211	3e-15	14.522878745280337	(EA)	0.038	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.211	NA	0.038
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109275216	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs660240-T	rs660240	0	660240	3_prime_UTR_variant	FALSE	NR	3e-15	14.522878745280337	NA	0.035	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.035
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109275684	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs629301-G	rs629301	0	629301	3_prime_UTR_variant	FALSE	0.219	4e-15	14.397940008672037	(EA)	0.037	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.219	NA	0.037
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109275684	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs629301-G	rs629301	0	629301	3_prime_UTR_variant	FALSE	NR	5e-15	14.301029995663981	NA	0.034	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.034
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109275908	NR	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222	NA	157	3648	rs646776-C	rs646776	0	646776	intergenic_variant	TRUE	0.219	4e-15	14.397940008672037	(EA)	0.037	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.219	NA	0.037
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109275908	NR	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222	NA	157	3648	rs646776-C	rs646776	0	646776	intergenic_variant	TRUE	NR	3e-15	14.522878745280337	NA	0.034	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.034
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109276674	NR	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222	NA	923	2882	rs3902354-C	rs3902354	0	3902354	intergenic_variant	TRUE	0.331	6e-9	8.221848749616356	(EA)	0.025	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.331	NA	0.025
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109276674	NR	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222	NA	923	2882	rs3902354-C	rs3902354	0	3902354	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	NA	0.022	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.022
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109279544	NR	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222	NA	3793	12	rs599839-G	rs599839	0	599839	intergenic_variant	TRUE	0.228	1e-15	15	(EA)	0.036	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.228	NA	0.036
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1p13.3	1	109279544	NR	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222	NA	3793	12	rs599839-G	rs599839	0	599839	intergenic_variant	TRUE	NR	5e-14	13.301029995663981	NA	0.032	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.032
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q25.2	1	178546177	NR	TEX35, C1orf220	NA	NA	ENSG00000240021, ENSG00000213057	NA	NA	rs4650994-G	rs4650994	0	4650994	intron_variant	FALSE	0.483	4e-8	7.3979400086720375	(EA)	0.021	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.483	NA	0.021
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q25.2	1	178546177	NR	TEX35, C1orf220	NA	NA	ENSG00000240021, ENSG00000213057	NA	NA	rs4650994-G	rs4650994	0	4650994	intron_variant	FALSE	NR	8e-9	8.096910013008056	NA	0.02	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.02
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q25.2	1	178560763	NR	C1orf220 - RNA5SP69	ENSG00000213057	ENSG00000201347	NA	11874	150	rs12753251-G	rs12753251	0	12753251	regulatory_region_variant	TRUE	0.501	2e-8	7.698970004336019	(EA)	0.021	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.501	NA	0.021
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q25.2	1	178560763	NR	C1orf220 - RNA5SP69	ENSG00000213057	ENSG00000201347	NA	11874	150	rs12753251-G	rs12753251	0	12753251	regulatory_region_variant	TRUE	NR	4e-9	8.397940008672037	NA	0.02	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.02
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q25.3	1	182174984	NR	LINC01344	NA	NA	ENSG00000228918	NA	NA	rs2489279-C	rs2489279	0	2489279	intron_variant	FALSE	NR	2e-6	5.698970004336019	NA	0.017	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.017
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q25.3	1	182199750	NR	LINC01344	NA	NA	ENSG00000228918	NA	NA	rs1689800-A	rs1689800	0	1689800	intron_variant	FALSE	NR	5e-6	5.301029995663981	NA	0.016	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.016
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q41	1	220796686	NR	MTARC1	NA	NA	ENSG00000186205	NA	NA	rs2642438-A	rs2642438	0	2642438	missense_variant	FALSE	0.293	5e-7	6.301029995663981	(EA)	0.021	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.293	NA	0.021
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	1q41	1	220796686	NR	MTARC1	NA	NA	ENSG00000186205	NA	NA	rs2642438-A	rs2642438	0	2642438	missense_variant	FALSE	NR	7e-8	7.154901959985743	NA	0.02	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.02
2018-08-17	29107063	Yashin AI	2017-10-26	Exp Gerontol	www.ncbi.nlm.nih.gov/pubmed/29107063	Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses.	Alzheimer's disease (age of onset)	12,169 European ancestry individuals, 2,078 Black individuals, 4,053 unknown ancestry individuals	NA	19q13.32	19	44892362	TOMM40	TOMM40	NA	NA	ENSG00000130204	NA	NA	rs2075650-?	rs2075650	0	2075650	intron_variant	FALSE	NR	5e-7	6.301029995663981	NA	1.5	[NR]	Illumina [up to 1329158]	N	Alzheimer's disease, age at onset	http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004847	GCST006120	Genome-wide genotyping array	NA	1.5	NA
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p12	1	119004219	TBX15, WARS2	TBX15 - WARS2	ENSG00000092607	ENSG00000116874	NA	14663	26997	rs10923724-T	rs10923724	0	10923724	intergenic_variant	TRUE	0.5802	4e-20	19.397940008672037	(EA)	0.0369	[0.029-0.045] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5802	NA	0.0369
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q24.2	1	170403362	GORAB	HAUS4P1 - GORAB-AS1	ENSG00000226967	ENSG00000231407	NA	32995	57091	rs10919388-C	rs10919388	0	10919388	intergenic_variant	TRUE	0.7242	4e-10	9.397940008672037	(EA)	0.028	[0.019-0.037] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.7242	NA	0.028
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q24.3	1	172364108	DNM3, PIGC	DNM3	NA	NA	ENSG00000197959	NA	NA	rs2001129-T	rs2001129	0	2001129	intron_variant	FALSE	0.4363	5e-16	15.301029995663981	(EA)	0.032	[0.024-0.04] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.4363	NA	0.032
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.2	1	176445645	PAPPA2	MORF4L1P7 - PAPPA2	ENSG00000225904	ENSG00000116183	NA	77244	17526	rs4650943-A	rs4650943	0	4650943	intron_variant	TRUE	0.5266	2e-8	7.698970004336019	(EA)	0.0267	[0.017-0.036] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5266	NA	0.0267
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q41	1	219479453	LYPLAL1	LYPLAL1-AS1 - NA	ENSG00000228536	NA	NA	20084	NA	rs1563352-T	rs1563352	0	1563352	intergenic_variant	TRUE	0.6972	6e-19	18.221848749616356	(EA)	0.0437	[0.034-0.053] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6972	NA	0.0437
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p14	2	66544868	MEIS1	MEIS1	NA	NA	ENSG00000143995	NA	NA	rs11897119-C	rs11897119	0	11897119	intron_variant	FALSE	0.39790000000000003	2e-8	7.698970004336019	(EA)	0.0233	[0.015-0.032] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.39790000000000003	NA	0.0233
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p14	2	67625557	ETAA1	LINC02831 - NA	ENSG00000224173	NA	NA	5012	NA	rs7598674-G	rs7598674	0	7598674	intron_variant	TRUE	0.6477999999999999	3e-9	8.522878745280337	(EA)	0.0254	[0.017-0.034] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6477999999999999	NA	0.0254
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2q24.3	2	164656581	GRB14, COBLL1	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs10195252-T	rs10195252	0	10195252	intron_variant	FALSE	0.5938	6e-14	13.221848749616356	(EA)	0.0318	[0.024-0.04] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5938	NA	0.0318
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2q32.1	2	187218396	CALCRL	RN7SKP42 - RNU6-989P	ENSG00000222845	ENSG00000199626	NA	95535	52302	rs13424740-T	rs13424740	0	13424740	intron_variant	TRUE	0.532	2e-12	11.698970004336019	(EA)	0.0282	[0.02-0.036] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.532	NA	0.0282
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p21.1	3	52588070	PBRM1	PBRM1	NA	NA	ENSG00000163939	NA	NA	rs2590838-G	rs2590838	0	2590838	intron_variant	FALSE	0.48850000000000005	2e-9	8.698970004336019	(EA)	0.0235	[0.016-0.031] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.48850000000000005	NA	0.0235
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	NA	NA	NA	ITIH1	NA	NA	NA	NA	NA	NA	rs2710323-T	rs2710323	0	2710323	NA	TRUE	0.5112	4e-9	8.397940008672037	(EA)	0.0235	[0.016-0.031] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.5112	NA	0.0235
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p14.1	3	64716214	ADAMTS9	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs4504165-T	rs4504165	0	4504165	intron_variant	FALSE	0.6995	7e-17	16.154901959985743	(EA)	0.0361	[0.028-0.045] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6995	NA	0.0361
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q22.1	3	129615390	PLXND1	PLXND1 - TMCC1	ENSG00000004399	ENSG00000172765	NA	8714	32402	rs10804591-A	rs10804591	0	10804591	intergenic_variant	TRUE	0.7927	6e-10	9.221848749616356	(EA)	0.0304	[0.021-0.04] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.7927	NA	0.0304
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q25.31	3	157079820	LEKR1	LEKR1 - LINC00880	ENSG00000197980	ENSG00000243629	NA	33691	1847	rs17451107-T	rs17451107	0	17451107	regulatory_region_variant	TRUE	0.6096	2e-11	10.698970004336019	(EA)	0.0281	[0.02-0.036] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6096	NA	0.0281
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	5q11.2	5	56565039	MAP3K1	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs3936510-T	rs3936510	0	3936510	intron_variant	FALSE	0.1875	2e-8	7.698970004336019	(EA)	0.0289	[0.019-0.039] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.1875	NA	0.0289
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p25.1	6	6736698	LY86	LY86 - BTF3P7	ENSG00000112799	ENSG00000219986	NA	81715	58217	rs912057-G	rs912057	0	912057	intron_variant	TRUE	0.6256999999999999	1e-13	13	(EA)	0.03	[0.022-0.038] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6256999999999999	NA	0.03
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.32	6	32255481	NOTCH4, C6orf10	TSBP1-AS1	NA	NA	ENSG00000225914	NA	NA	rs3130320-C	rs3130320	0	3130320	intron_variant	FALSE	0.6281	7e-8	7.154901959985743	(EA)	0.0224	[0.014-0.03] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.6281	NA	0.0224
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.32	6	32377912	NOTCH4, C6orf10	TSBP1-AS1	NA	NA	ENSG00000225914	NA	NA	rs2894254-T	rs2894254	0	2894254	intron_variant	FALSE	0.8879	1e-7	7	(EA)	0.0337	[0.021-0.046] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.8879	NA	0.0337
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.32	6	32480621	NOTCH4, C6orf10	HLA-DRB9 - HLA-DRB5	ENSG00000226035	ENSG00000198502	NA	7121	36732	rs9378213-G	rs9378213	0	9378213	intergenic_variant	TRUE	0.41690000000000005	4e-8	7.3979400086720375	(EA)	0.0227	[0.015-0.031] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.41690000000000005	NA	0.0227
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.1	6	43796814	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	10327	48064	rs1358980-T	rs1358980	0	1358980	regulatory_region_variant	TRUE	0.4742	1e-20	20	(EA)	0.0401	[0.032-0.049] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.4742	NA	0.0401
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6q22.33	6	127133993	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs7766106-T	rs7766106	0	7766106	intron_variant	FALSE	0.4821	1e-26	26	(EA)	0.0424	[0.035-0.05] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.4821	NA	0.0424
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	25831489	NFE2L3	NA	NA	NA	NA	NA	NA	rs1055144-T	rs1055144	0	1055144	non_coding_transcript_exon_variant	TRUE	0.1997	3e-14	13.522878745280337	(EA)	0.038	[0.028-0.048] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.1997	NA	0.038
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7p15.2	7	27184152	HOXA11	HOXA11	NA	NA	ENSG00000005073	NA	NA	rs7801581-T	rs7801581	0	7801581	intron_variant	FALSE	0.2443	1e-8	8	(EA)	0.0273	[0.018-0.037] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.2443	NA	0.0273
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	7q11.23	7	73471480	BAZ1B	BAZ1B	NA	NA	ENSG00000009954	NA	NA	rs6976930-G	rs6976930	0	6976930	intron_variant	FALSE	0.8132	1e-8	8	(EA)	0.0294	[0.019-0.039] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.8132	NA	0.0294
2017-08-22	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Waist-to-hip ratio adjusted for body mass index	2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	8p21.2	8	23735787	NKX2-6	NKX2-6 - NA	ENSG00000180053	NA	NA	29031	NA	rs10101061-T	rs10101061	0	10101061	intron_variant	TRUE	0.7485999999999999	2e-8	7.698970004336019	(EA)	0.0295	[0.019-0.04] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	BMI-adjusted waist-hip ratio, physical activity measurement	http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002	GCST004576	Genome-wide genotyping array	0.7485999999999999	NA	0.0295
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	3q23	3	141428572	ZBTB38	ZBTB38	NA	NA	ENSG00000177311	NA	NA	rs7650602-C	rs7650602	0	7650602	intron_variant	FALSE	0.4495	2e-9	8.698970004336019	NA	0.02187854	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4495	NA	0.02187854
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4p16.1	4	7043344	TADA2B, RP11-367J11.2	TADA2B	NA	NA	ENSG00000173011	NA	NA	rs568868093-TGCGGCG	rs568868093	0	568868093	intron_variant	FALSE	0.6065	7e-14	13.154901959985743	NA	0.02742936	[0.02-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.6065	NA	0.02742936
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4p14	4	38131378	TBC1D1	TBC1D1	NA	NA	ENSG00000065882	NA	NA	rs633059-G	rs633059	0	633059	intron_variant	FALSE	0.333	3e-11	10.522878745280337	NA	0.02517467	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.333	NA	0.02517467
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4p14	4	38370434	RP11-83C7.1	LINC02513	NA	NA	ENSG00000248227	NA	NA	rs1386622-G	rs1386622	0	1386622	intron_variant	FALSE	0.6803	2e-55	54.69897000433602	NA	0.06026967	[0.053-0.068] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.6803	NA	0.06026967
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4p14	4	38652152	RP11-617D20.1, AC021860.1	KLF3-AS1	NA	NA	ENSG00000231160	NA	NA	rs58785573-T	rs58785573	0	58785573	intron_variant	FALSE	0.588	3e-24	23.522878745280337	NA	0.0367388	[0.03-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.588	NA	0.0367388
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4q12	4	54530155	intergenic	LINC02283 - LINC02260	ENSG00000248184	ENSG00000250456	NA	174201	73056	rs218243-G	rs218243	0	218243	intergenic_variant	TRUE	0.1874	2e-9	8.698970004336019	NA	0.02782587	[0.019-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.1874	NA	0.02782587
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4q13.3	4	73835795	CXCL6	CXCL8 - CXCL6	ENSG00000169429	ENSG00000124875	NA	92079	845	rs62312418-A	rs62312418	0	62312418	intergenic_variant	TRUE	0.4048	4e-24	23.397940008672037	NA	0.03703704	[0.03-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4048	NA	0.03703704
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4q13.3	4	74094279	CXCL2	PPBPP2 - CXCL2	ENSG00000248848	ENSG00000081041	NA	38880	2761	rs11725704-G	rs11725704	0	11725704	regulatory_region_variant	TRUE	0.3762	4e-36	35.39794000867204	NA	0.04616097	[0.039-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.3762	NA	0.04616097
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	NA	NA	NA	ANTXR2	NA	NA	NA	NA	NA	NA	rs139246187-TAGAC	rs139246187	0	79283094	NA	TRUE	0.5295	2e-14	13.698970004336019	NA	0.02722963	[0.02-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.5295	NA	0.02722963
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4q21.22	4	82964057	LIN54	LIN54	NA	NA	ENSG00000189308	NA	NA	rs60065504-C	rs60065504	0	60065504	intron_variant	FALSE	0.4458	1e-9	9	NA	0.02181981	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4458	NA	0.02181981
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4q24	4	102587546	NFKB1	NFKB1	NA	NA	ENSG00000109320	NA	NA	rs4648045-C	rs4648045	0	4648045	intron_variant	FALSE	0.3742	2e-21	20.69897000433602	NA	0.03499196	[0.028-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.3742	NA	0.03499196
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4q24	4	104943373	RP11-556I14.1, RP11-556I14.2	CXXC4-AS1 - RNU6-351P	ENSG00000245384	ENSG00000251906	NA	208827	31299	rs199741557-A	rs199741557	0	199741557	intron_variant	TRUE	0.0325	4e-11	10.397940008672037	NA	0.0675629	[0.048-0.088] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0325	NA	0.0675629
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	4q24	4	105204229	TET2	TET2	NA	NA	ENSG00000168769	NA	NA	rs546941547-A	rs546941547	0	546941547	intron_variant	FALSE	0.4615	7e-25	24.154901959985743	NA	0.03688624	[0.03-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4615	NA	0.03688624
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	5p13.2	5	35852868	IL7R	IL7R	NA	NA	ENSG00000168685	NA	NA	rs151286246-C	rs151286246	0	151286246	5_prime_UTR_variant	FALSE	0.2592	3e-29	28.522878745280337	NA	0.04573874	[0.038-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.2592	NA	0.04573874
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	NA	NA	NA	intergenic	NA	NA	NA	NA	NA	NA	chr5:71695918-G	chr5:71695918	0	NA	NA	TRUE	0.4665	7e-12	11.154901959985743	NA	0.02486462	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4665	NA	0.02486462
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	5q31.1	5	132474066	C5orf56	IRF1, IRF1-AS1	NA	NA	ENSG00000125347, ENSG00000197536	NA	NA	rs140316257-T	rs140316257	1	68035341	intron_variant	FALSE	0.7332	7e-11	10.154901959985743	NA	0.02625749	[0.018-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.7332	NA	0.02625749
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	NA	NA	NA	ADRB2	NA	NA	NA	NA	NA	NA	chr5:148206473-C	chr5:148206473	0	NA	NA	TRUE	0.5497	4e-13	12.397940008672037	NA	0.02600509	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.5497	NA	0.02600509
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	5q33.3	5	159012157	EBF1	EBF1	NA	NA	ENSG00000164330	NA	NA	rs56356600-T	rs56356600	0	56356600	intron_variant	FALSE	0.0839	4e-9	8.397940008672037	NA	0.038255	[0.025-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0839	NA	0.038255
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	5q35.3	5	177310719	MXD3	MXD3	NA	NA	ENSG00000213347	NA	NA	rs13190036-G	rs13190036	0	13190036	non_coding_transcript_exon_variant	FALSE	0.8923	3e-13	12.522878745280337	NA	0.04239853	[0.031-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.8923	NA	0.04239853
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	6p22.3	6	24819824	FAM65B	RIPOR2	NA	NA	ENSG00000111913	NA	NA	rs6911302-C	rs6911302	0	6911302	intron_variant	FALSE	0.5516	6e-23	22.221848749616356	NA	0.03548046	[0.028-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.5516	NA	0.03548046
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	6p22.1	6	29955574	HLA-W	HLA-A - HLA-W	ENSG00000235657	ENSG00000235144	NA	9690	1022	rs2904758-A	rs2904758	0	2904758	intron_variant	TRUE	0.7187	6e-17	16.221848749616356	NA	0.03315845	[0.025-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.7187	NA	0.03315845
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	6p22.1	6	29956517	HLA-W	HLA-A - HLA-W	ENSG00000235657	ENSG00000235144	NA	10633	79	rs73725598-C	rs73725598	0	73725598	intron_variant	TRUE	0.0934	2e-9	8.698970004336019	NA	0.03755279	[0.025-0.05] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0934	NA	0.03755279
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	6p21.33	6	31330761	intergenic	LINC02571 - HLA-B	ENSG00000256166	ENSG00000206450	NA	29119	23111	rs530257728-GAAATAAAGCAGATTT	rs530257728	0	530257728	intron_variant	TRUE	0.0801	5e-21	20.30102999566398	NA	0.06499605	[0.051-0.079] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0801	NA	0.06499605
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	6p21.33	6	31572779	LTA	LTA, LTA, LTA, LTA, LTA, LTA, LTA	NA	NA	ENSG00000223919, ENSG00000231408, ENSG00000230279, ENSG00000226979, ENSG00000238130, ENSG00000173503, ENSG00000226275	NA	NA	rs2229094-C	rs2229094	0	2229094	missense_variant	FALSE	0.2536	4e-15	14.397940008672037	NA	0.03213321	[0.024-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.2536	NA	0.03213321
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	6p21.32	6	32663430	HLA-DQB1	HLA-DQB1, HLA-DQB1, HLA-DQB1	NA	NA	ENSG00000179344, ENSG00000206302, ENSG00000206237	NA	NA	rs9274235-T	rs9274235	0	9274235	non_coding_transcript_exon_variant	FALSE	0.3487	4e-9	8.397940008672037	NA	0.02287324	[0.015-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.3487	NA	0.02287324
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1q31.3	1	197812068	intergenic	DENND1B - C1orf53	ENSG00000213047	ENSG00000203724	NA	36372	90562	rs12134279-T	rs12134279	0	12134279	regulatory_region_variant	TRUE	0.2078	1e-9	9	NA	0.02673046	[0.018-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.2078	NA	0.02673046
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1q32.1	1	200933479	MROH3P	MROH3P	NA	NA	ENSG00000233217	NA	NA	rs11583546-A	rs11583546	0	11583546	intron_variant	FALSE	0.298	3e-9	8.522878745280337	NA	0.02312652	[0.015-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.298	NA	0.02312652
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	1q42.13	1	226982597	ADCK3	COQ8A	NA	NA	ENSG00000163050	NA	NA	rs2297412-G	rs2297412	0	2297412	non_coding_transcript_exon_variant	FALSE	0.4754	3e-11	10.522878745280337	NA	0.02386963	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4754	NA	0.02386963
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2p23.3	2	24016320	MFSD2B	MFSD2B	NA	NA	ENSG00000205639	NA	NA	rs113601626-TCCTGGC	rs113601626	0	113601626	intron_variant	FALSE	0.1352	7e-13	12.154901959985743	NA	0.03731268	[0.027-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.1352	NA	0.03731268
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2p23.3	2	25265950	DNMT3A	DNMT3A	NA	NA	ENSG00000119772	NA	NA	rs7578575-A	rs7578575	0	7578575	intron_variant	FALSE	0.2942	4e-17	16.397940008672037	NA	0.03323868	[0.026-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.2942	NA	0.03323868
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2p21	2	43224818	ZFP36L2	ZFP36L2	NA	NA	ENSG00000152518	NA	NA	rs149290349-A	rs149290349	0	149290349	missense_variant	FALSE	0.0761	9e-39	38.045757490560675	NA	0.08961224	[0.076-0.103] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0761	NA	0.08961224
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q12.1	2	102437989	IL18RAP	IL18RAP	NA	NA	ENSG00000115607	NA	NA	rs2058660-A	rs2058660	0	2058660	intron_variant	FALSE	0.7745	4e-9	8.397940008672037	NA	0.02509048	[0.017-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.7745	NA	0.02509048
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q13	2	110841705	ACOXL	ACOXL	NA	NA	ENSG00000153093	NA	NA	rs10210955-C	rs10210955	0	10210955	intron_variant	FALSE	0.4903	7e-16	15.154901959985743	NA	0.02869848	[0.022-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4903	NA	0.02869848
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q13	2	111473966	MIR4435-1HG	MIR4435-2HG	NA	NA	ENSG00000172965	NA	NA	rs11695997-A	rs11695997	0	11695997	intron_variant	FALSE	0.0798	2e-21	20.69897000433602	NA	0.06834993	[0.054-0.082] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0798	NA	0.06834993
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q14.1	2	113106902	IL1RN	RNU6-1180P - IL1RN	ENSG00000201805	ENSG00000136689	NA	19991	312	rs11473501-TAAA	rs11473501	0	11473501	regulatory_region_variant	TRUE	0.4826	4e-9	8.397940008672037	NA	0.02101972	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4826	NA	0.02101972
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q24.2	2	160483989	RBMS1	RBMS1	NA	NA	ENSG00000153250	NA	NA	rs7419612-A	rs7419612	0	7419612	intron_variant	FALSE	0.19	4e-12	11.397940008672037	NA	0.03174877	[0.023-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.19	NA	0.03174877
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q31.3	2	181155969	AC104820.2	LINC01934	NA	NA	ENSG00000234663	NA	NA	rs59395276-C	rs59395276	0	59395276	intron_variant	FALSE	0.3209	2e-17	16.69897000433602	NA	0.03262949	[0.025-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.3209	NA	0.03262949
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q31.3	2	181285215	AC104820.2	LINC01934	NA	NA	ENSG00000234663	NA	NA	rs13390610-T	rs13390610	0	13390610	intron_variant	FALSE	0.4244	8e-12	11.096910013008056	NA	0.02475417	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4244	NA	0.02475417
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q31.3	2	181459039	ITGA4	ITGA4	NA	NA	ENSG00000115232	NA	NA	rs1375493-A	rs1375493	0	1375493	non_coding_transcript_exon_variant	FALSE	0.5564	1e-10	10	NA	0.02315471	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.5564	NA	0.02315471
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q33.1	2	201289197	ALS2CR12	FLACC1	NA	NA	ENSG00000155749	NA	NA	rs6743068-G	rs6743068	0	6743068	intron_variant	FALSE	0.7307	1e-12	12	NA	0.0284983	[0.021-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.7307	NA	0.0284983
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q35	2	218135259	CXCR2	CXCR2	NA	NA	ENSG00000180871	NA	NA	rs55799208-A	rs55799208	0	55799208	missense_variant	FALSE	0.0029	3e-20	19.522878745280337	NA	0.3287534	[0.26-0.4] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0029	NA	0.3287534
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	2q35	2	218156235	intergenic	CXCR2 - CXCR1	ENSG00000180871	ENSG00000163464	NA	18984	6606	rs114050631-T	rs114050631	0	114050631	regulatory_region_variant	TRUE	0.0106	1e-9	9	NA	0.116977	[0.079-0.155] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0106	NA	0.116977
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	3p24.1	3	28261539	CMC1	CMC1	NA	NA	ENSG00000187118	NA	NA	rs4502545-A	rs4502545	0	4502545	intron_variant	FALSE	0.1762	4e-12	11.397940008672037	NA	0.03256658	[0.023-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.1762	NA	0.03256658
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	3p22.1	3	42865920	ACKR2	ACKR2, KRBOX1, CYP8B1	NA	NA	ENSG00000144648, ENSG00000240747, ENSG00000180432	NA	NA	rs141413113-TCTCC	rs141413113	1	56176584	3_prime_UTR_variant	FALSE	0.3816	2e-9	8.698970004336019	NA	0.02198668	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.3816	NA	0.02198668
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	3p21.31	3	47046347	SETD2	SETD2	NA	NA	ENSG00000181555	NA	NA	rs13063578-A	rs13063578	0	13063578	intron_variant	FALSE	0.4017	3e-18	17.522878745280337	NA	0.03160705	[0.024-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.4017	NA	0.03160705
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	3p13	3	71332916	FOXP1	FOXP1	NA	NA	ENSG00000114861	NA	NA	rs71298382-G	rs71298382	0	71298382	5_prime_UTR_variant	FALSE	0.0286	2e-16	15.698970004336019	NA	0.09547253	[0.073-0.118] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.0286	NA	0.09547253
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	NA	NA	NA	FOXP1	NA	NA	NA	NA	NA	NA	chr3:71410012-C	chr3:71410012_T_C	0	NA	NA	TRUE	0.1941	4e-11	10.397940008672037	NA	0.03031303	[0.021-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.1941	NA	0.03031303
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	3q21.3	3	128479261	GATA2	DNAJB8-AS1 - GATA2	ENSG00000242049	ENSG00000179348	NA	6944	166	rs2713579-A	rs2713579	0	2713579	intergenic_variant	TRUE	0.6549	3e-16	15.522878745280337	NA	0.03089935	[0.023-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.6549	NA	0.03089935
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	3q21.3	3	128604581	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	28495	15388	rs6782228-C	rs6782228	0	6782228	intergenic_variant	TRUE	0.2679	3e-23	22.522878745280337	NA	0.04021163	[0.032-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.2679	NA	0.04021163
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Lymphocyte percentage of white cells	171,748 European ancestry individuals	NA	3q21.3	3	128693181	intergenic	RPN1 - RAB7A	ENSG00000163902	ENSG00000075785	NA	12106	488	rs6785206-G	rs6785206	0	6785206	intergenic_variant	TRUE	0.9197	8e-20	19.096910013008056	NA	0.06049037	[0.047-0.074] unit increase	Affymetrix [~ 2500000] (imputed)	N	lymphocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007993	GCST004632	Genome-wide genotyping array	0.9197	NA	0.06049037
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q22.2	11	102857881	Intergenic	MMP3 - MMP12	ENSG00000149968	ENSG00000262406	NA	14272	4855	rs644885-A	rs644885	0	644885	intergenic_variant	TRUE	0.215	2e-6	5.698970004336019	NA	0.052	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.215	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144558611	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	13627	rs6537294-A	rs6537294	0	6537294	intron_variant	TRUE	0.384	1e-9	9	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.384	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144569207	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	3031	rs12501071-T	rs12501071	0	12501071	intron_variant	TRUE	0.409	2e-9	8.698970004336019	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.409	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78461658	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs1964678-A	rs1964678	0	1964678	intron_variant	FALSE	0.453	4e-9	8.397940008672037	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.453	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78482032	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs8042260-A	rs8042260	0	8042260	intron_variant	FALSE	0.451	4e-9	8.397940008672037	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.451	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78476788	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs12916801-A	rs12916801	0	12916801	intron_variant	FALSE	0.452	6e-9	8.221848749616356	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.452	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78675059	Intergenic	CHRNB4	NA	NA	ENSG00000117971	NA	NA	rs12902602-A	rs12902602	0	12902602	intron_variant	FALSE	0.608	5e-8	7.301029995663981	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.608	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78479204	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs11072766-T	rs11072766	0	11072766	intron_variant	FALSE	0.2	8e-7	6.096910013008056	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.2	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78471275	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs7174190-T	rs7174190	0	7174190	intron_variant	FALSE	0.199	9e-7	6.045757490560675	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.199	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78487459	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs12101809-T	rs12101809	0	12101809	intron_variant	FALSE	0.2	9e-7	6.045757490560675	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.2	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78491341	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs28511883-T	rs28511883	0	28511883	intron_variant	FALSE	0.2	9e-7	6.045757490560675	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.2	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q22.2	11	102859026	Intergenic	MMP3 - MMP12	ENSG00000149968	ENSG00000262406	NA	15417	3710	rs660599-A	rs660599	0	660599	intergenic_variant	TRUE	0.219	1e-6	6	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.219	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	10q23.1	10	80470390	TSPAN14	TSPAN14	NA	NA	ENSG00000108219	NA	NA	rs2343306-T	rs2343306	0	2343306	intron_variant	FALSE	0.775	2e-6	5.698970004336019	NA	0.053	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.775	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144542079	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	30159	rs6828540-A	rs6828540	0	6828540	intron_variant	TRUE	0.387	7e-10	9.154901959985743	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.387	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144551799	Intergenic	GYPA - KRT18P51	ENSG00000170180	ENSG00000250504	NA	411048	20439	rs1818444-A	rs1818444	0	1818444	intron_variant	TRUE	0.369	2e-9	8.698970004336019	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.369	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78683513	Intergenic	CHRNB4	NA	NA	ENSG00000117971	NA	NA	rs72743199-A	rs72743199	0	72743199	intron_variant	FALSE	0.61	2e-8	7.698970004336019	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.61	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78662037	Intergenic	CHRNB4	NA	NA	ENSG00000117971	NA	NA	rs12899135-A	rs12899135	0	12899135	intron_variant	FALSE	0.608	4e-8	7.3979400086720375	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.608	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78465571	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2938674-A	rs2938674	0	2938674	intron_variant	FALSE	0.2	5e-7	6.301029995663981	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.2	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78451950	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2656072-A	rs2656072	0	2656072	intron_variant	FALSE	0.201	6e-7	6.221848749616356	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.201	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78449934	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2656073-T	rs2656073	0	2656073	intron_variant	FALSE	0.2	6e-7	6.221848749616356	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.2	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78449042	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2656074-T	rs2656074	0	2656074	intron_variant	FALSE	0.2	7e-7	6.154901959985743	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.2	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78446028	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2568490-T	rs2568490	0	2568490	intron_variant	FALSE	0.2	7e-7	6.154901959985743	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.2	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78480464	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs35031105-T	rs35031105	0	35031105	intron_variant	FALSE	0.201	7e-7	6.154901959985743	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.201	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78733174	Intergenic	CHRNB4 - ADAMTS7	ENSG00000117971	ENSG00000136378	NA	5420	26032	rs2869561-T	rs2869561	0	2869561	intron_variant	TRUE	0.627	1e-6	6	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.627	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	10q23.1	10	80492013	TSPAN14	TSPAN14	NA	NA	ENSG00000108219	NA	NA	rs7910643-A	rs7910643	0	7910643	intron_variant	FALSE	0.812	5e-6	5.301029995663981	NA	0.054	NR unit increase	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.812	NA	NA
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p24.1	2	21008652	NR	APOB	NA	NA	ENSG00000084674	NA	NA	rs676210-G	rs676210	0	676210	missense_variant	FALSE	0.757	1e-7	7	(Hispanic)	0.076	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.757	NA	0.076
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p24.1	2	21008652	NR	APOB	NA	NA	ENSG00000084674	NA	NA	rs676210-G	rs676210	0	676210	missense_variant	FALSE	NR	6e-58	57.221848749616356	NA	0.066	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.066
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p24.1	2	21009932	NR	APOB	NA	NA	ENSG00000084674	NA	NA	rs1041968-G	rs1041968	0	1041968	synonymous_variant	FALSE	0.511	4e-15	14.397940008672037	(EA)	0.03	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.511	NA	0.03
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p24.1	2	21009932	NR	APOB	NA	NA	ENSG00000084674	NA	NA	rs1041968-G	rs1041968	0	1041968	synonymous_variant	FALSE	NR	3e-18	17.522878745280337	NA	0.031	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.031
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p24.1	2	21011100	NR	APOB	NA	NA	ENSG00000084674	NA	NA	rs533617-T	rs533617	0	533617	missense_variant	FALSE	0.96	9e-20	19.045757490560675	(EA)	0.087	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.96	NA	0.087
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p24.1	2	21011100	NR	APOB	NA	NA	ENSG00000084674	NA	NA	rs533617-T	rs533617	0	533617	missense_variant	FALSE	NR	7e-21	20.154901959985743	NA	0.087	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.087
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p24.1	2	21014672	NR	APOB	NA	NA	ENSG00000084674	NA	NA	rs673548-G	rs673548	0	673548	intron_variant	FALSE	0.785	8e-51	50.096910013008056	(EA)	0.069	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.785	NA	0.069
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p24.1	2	21014672	NR	APOB	NA	NA	ENSG00000084674	NA	NA	rs673548-G	rs673548	0	673548	intron_variant	FALSE	0.754	3e-7	6.522878745280337	(Hispanic)	0.074	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.754	NA	0.074
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p24.1	2	21014672	NR	APOB	NA	NA	ENSG00000084674	NA	NA	rs673548-G	rs673548	0	673548	intron_variant	FALSE	NR	1e-56	56	NA	0.065	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.065
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p24.1	2	21041028	NR	APOB	NA	NA	ENSG00000084674	NA	NA	rs1367117-G	rs1367117	0	1367117	missense_variant	FALSE	NR	3e-6	5.522878745280337	NA	0.018	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.018
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p14	2	65048915	NR	LINC02576, LINC02245	NA	NA	ENSG00000232613, ENSG00000237638	NA	NA	rs1009360-T	rs1009360	0	1009360	intron_variant	FALSE	0.565	6e-6	5.221848749616356	(EA)	0.017	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.565	NA	0.017
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p14	2	65048915	NR	LINC02576, LINC02245	NA	NA	ENSG00000232613, ENSG00000237638	NA	NA	rs1009360-T	rs1009360	0	1009360	intron_variant	FALSE	NR	3e-7	6.522878745280337	NA	0.018	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.018
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2p14	2	65057489	NR	CEP68	NA	NA	ENSG00000011523	NA	NA	rs2540948-T	rs2540948	0	2540948	intron_variant	FALSE	NR	8e-6	5.096910013008056	NA	0.016	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.016
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2q24.3	2	164651879	NR	GRB14 - COBLL1	ENSG00000115290	ENSG00000082438	NA	30397	1745	rs10184004-C	rs10184004	0	10184004	TF_binding_site_variant	TRUE	0.594	2e-15	14.698970004336019	(EA)	0.03	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.594	NA	0.03
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2q24.3	2	164651879	NR	GRB14 - COBLL1	ENSG00000115290	ENSG00000082438	NA	30397	1745	rs10184004-C	rs10184004	0	10184004	TF_binding_site_variant	TRUE	NR	4e-19	18.397940008672037	NA	0.032	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.032
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2q24.3	2	164684290	NR	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs12328675-T	rs12328675	0	12328675	3_prime_UTR_variant	FALSE	0.872	2e-16	15.698970004336019	(EA)	0.046	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.872	NA	0.046
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2q24.3	2	164684290	NR	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs12328675-T	rs12328675	0	12328675	3_prime_UTR_variant	FALSE	NR	3e-18	17.522878745280337	NA	0.046	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.046
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	rs7607980-T	rs7607980	0	7607980	NA	TRUE	0.873	2e-16	15.698970004336019	(EA)	0.046	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.873	NA	0.046
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	rs7607980-T	rs7607980	0	7607980	NA	TRUE	NR	2e-17	16.69897000433602	NA	0.045	unit decrease	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.045
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2q35	2	218835276	NR	PRKAG3 - RPL23AP31	ENSG00000115592	ENSG00000232625	NA	3190	6323	rs78058190-G	rs78058190	0	78058190	intergenic_variant	TRUE	0.948	2e-12	11.698970004336019	(EA)	0.06	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.948	NA	0.06
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2q35	2	218835276	NR	PRKAG3 - RPL23AP31	ENSG00000115592	ENSG00000232625	NA	3190	6323	rs78058190-G	rs78058190	0	78058190	intergenic_variant	TRUE	NR	2e-13	12.698970004336019	NA	0.061	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.061
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2q36.3	2	226229029	NR	NA	NA	NA	NA	NA	NA	rs2943641-T	rs2943641	0	2943641	intergenic_variant	TRUE	0.355	2e-23	22.69897000433602	(EA)	0.039	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.355	NA	0.039
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2q36.3	2	226229029	NR	NA	NA	NA	NA	NA	NA	rs2943641-T	rs2943641	0	2943641	intergenic_variant	TRUE	NR	3e-26	25.522878745280337	NA	0.039	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.039
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2q36.3	2	226234464	NR	NYAP2 - MIR5702	ENSG00000144460	ENSG00000263363	NA	580446	424246	rs2943645-C	rs2943645	0	2943645	regulatory_region_variant	TRUE	0.358	9e-23	22.045757490560675	(EA)	0.039	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	0.358	NA	0.039
2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals	NA	2q36.3	2	226234464	NR	NYAP2 - MIR5702	ENSG00000144460	ENSG00000263363	NA	580446	424246	rs2943645-C	rs2943645	0	2943645	regulatory_region_variant	TRUE	NR	2e-25	24.69897000433602	NA	0.038	unit increase	Affymetrix [at least 7091467] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST007140	Genome-wide genotyping array	NA	NA	0.038
2017-11-20	29051540	Marenholz I	2017-10-20	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29051540	Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.	Food allergy	497 European ancestry cases, 2,387 European ancestry controls	1,050 European ancestry cases, 2,510 European ancestry controls	11q13.5	11	76570549	C11orf30, LRRC32	EMSY - LINC02757	ENSG00000158636	ENSG00000255363	NA	17524	37304	rs2212434-T	rs2212434	0	2212434	intergenic_variant	TRUE	0.459	9e-11	10.045757490560675	NA	1.29	(discovery)	Illumina [5405832] (imputed)	N	food allergy measurement	http://www.ebi.ac.uk/efo/EFO_0007016	GCST004979	Genome-wide genotyping array	0.459	1.29	NA
2017-11-20	29051540	Marenholz I	2017-10-20	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29051540	Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.	Food allergy	497 European ancestry cases, 2,387 European ancestry controls	1,050 European ancestry cases, 2,510 European ancestry controls	18q21.33	18	63775385	SERPINB7	SERPINB7	NA	NA	ENSG00000166396	NA	NA	rs12964116-G	rs12964116	0	12964116	5_prime_UTR_variant	FALSE	0.050	2e-8	7.698970004336019	NA	1.9	(discovery)	Illumina [5405832] (imputed)	N	food allergy measurement	http://www.ebi.ac.uk/efo/EFO_0007016	GCST004979	Genome-wide genotyping array	0.05	1.9	NA
2017-11-20	29051540	Marenholz I	2017-10-20	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29051540	Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.	Peanut allergy	230 European ancestry cases, 2,387 European ancestry controls	438 European ancestry cases, 2,510 European ancestry controls	20p11.23	20	21239574	PLK1S1	KIZ	NA	NA	ENSG00000088970	NA	NA	rs17664036-C	rs17664036	0	17664036	intron_variant	FALSE	0.059	2e-6	5.698970004336019	NA	2.02	(discovery)	Illumina [5405832] (imputed)	N	peanut allergy measurement	http://www.ebi.ac.uk/efo/EFO_0007017	GCST004980	Genome-wide genotyping array	0.059	2.02	NA
2017-11-20	29051540	Marenholz I	2017-10-20	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29051540	Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.	Hen's egg allergy	288 European ancestry cases, 2,387 European ancestry controls	416 European ancestry cases, 2,510 European ancestry controls	4q22.3	4	95103943	BMPR1B	BMPR1B	NA	NA	ENSG00000138696	NA	NA	rs17023017-G	rs17023017	0	17023017	intron_variant	FALSE	0.122	7e-7	6.154901959985743	NA	1.54	(discovery)	Illumina [5405832] (imputed)	N	egg allergy measurement	http://www.ebi.ac.uk/efo/EFO_0007018	GCST004977	Genome-wide genotyping array	0.122	1.54	NA
2017-11-20	29051540	Marenholz I	2017-10-20	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29051540	Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.	Hen's egg allergy	288 European ancestry cases, 2,387 European ancestry controls	416 European ancestry cases, 2,510 European ancestry controls	18q21.33	18	63846741	SERPINB2, SERPINB7	SERPINB7 - SERPINB2	ENSG00000166396	ENSG00000197632	NA	41365	24951	rs1243064-A	rs1243064	0	1243064	intergenic_variant	TRUE	0.259	8e-8	7.096910013008056	NA	1.65	(discovery)	Illumina [5405832] (imputed)	N	egg allergy measurement	http://www.ebi.ac.uk/efo/EFO_0007018	GCST004977	Genome-wide genotyping array	0.259	1.65	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	7p21.2	7	15013235	DGKB	GTF3AP5 - NA	ENSG00000225816	NA	NA	27161	NA	rs6960043-C	rs6960043	0	6960043	intergenic_variant	TRUE	0.470992007052675	3e-7	6.522878745280337	NA	1.06	[1.04-1.09]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.470992007052675	1.06	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	7p15.1	7	28156794	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs849135-G	rs849135	0	849135	intron_variant	FALSE	0.516793139712259	3e-17	16.522878745280337	NA	1.11	[1.08-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.516793139712259	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	7p13	7	44205764	GCK	YKT6	NA	NA	ENSG00000106636	NA	NA	rs10278336-A	rs10278336	0	10278336	intron_variant	FALSE	0.497434854705026	6e-6	5.221848749616356	NA	1.07	[1.04-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.497434854705026	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	8p11.21	8	41661730	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs516946-C	rs516946	0	516946	non_coding_transcript_exon_variant	FALSE	0.764476252935483	2e-10	9.698970004336019	NA	1.09	[1.06-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.764476252935483	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	8q22.1	8	94925274	TP53INP1	NDUFAF6	NA	NA	ENSG00000156170	NA	NA	rs7845219-T	rs7845219	0	7845219	intron_variant	FALSE	0.52252758480133	5e-6	5.301029995663981	NA	1.06	[1.03-1.08]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.52252758480133	1.06	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	8q24.11	8	117172786	SLC30A8	SLC30A8	NA	NA	ENSG00000164756	NA	NA	rs3802177-G	rs3802177	0	3802177	3_prime_UTR_variant	FALSE	0.662967097343608	1e-21	21	NA	1.14	[1.11-1.17]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.662967097343608	1.14	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	9p24.2	9	4292083	GLIS3	GLIS3	NA	NA	ENSG00000107249	NA	NA	rs10758593-A	rs10758593	0	10758593	intron_variant	FALSE	0.424978205720837	3e-7	6.522878745280337	NA	1.06	[1.04-1.09]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.424978205720837	1.06	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	9p21.3	9	22134095	CDKN2A/B	CDKN2B-AS1 - DMRTA1	ENSG00000240498	ENSG00000176399	NA	5992	312729	rs10811661-T	rs10811661	0	10811661	intergenic_variant	TRUE	0.824988872842347	4e-27	26.397940008672037	NA	1.18	[1.15-1.22]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.824988872842347	1.18	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	9q21.31	9	79290675	TLE4	NA	NA	NA	NA	NA	NA	rs17791513-A	rs17791513	0	17791513	intergenic_variant	TRUE	0.910610002991984	3e-7	6.522878745280337	NA	1.12	[1.07-1.17]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.910610002991984	1.12	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	9q21.32	9	81694033	TLE1	TLE1 - RNU6-1035P	ENSG00000196781	ENSG00000207206	NA	4486	31210	rs2796441-G	rs2796441	0	2796441	intron_variant	TRUE	0.574668679623249	5e-9	8.301029995663981	NA	1.07	[1.05-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.574668679623249	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	10p13	10	12265895	CDC123, CAMK1D	CDC123 - RN7SL198P	ENSG00000151465	ENSG00000264036	NA	15306	62237	rs11257655-T	rs11257655	0	11257655	TF_binding_site_variant	TRUE	0.231035682630139	2e-6	5.698970004336019	NA	1.07	[1.04-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.231035682630139	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	10q22.3	10	79182874	ZMIZ1	ZMIZ1	NA	NA	ENSG00000108175	NA	NA	rs12571751-A	rs12571751	0	12571751	intron_variant	FALSE	0.517057010272647	1e-10	10	NA	1.08	[1.05-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.517057010272647	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	10q23.33	10	92703125	HHEX, IDE	HHEX - Y_RNA	ENSG00000152804	ENSG00000199964	NA	7478	7374	rs1111875-C	rs1111875	0	1111875	intergenic_variant	TRUE	0.581455301385325	2e-19	18.69897000433602	NA	1.11	[1.09-1.14]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.581455301385325	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	10q25.2	10	112998590	TCF7L2	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs7903146-T	rs7903146	0	7903146	intron_variant	FALSE	0.268379563153031	1e-139	139	NA	1.39	[1.35-1.42]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.268379563153031	1.39	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	NA	NA	NA	KCNQ1	NA	NA	NA	NA	NA	NA	rs163184-G	rs163184	0	163184	intron_variant	TRUE	0.498159618830787	1e-11	11	NA	1.09	[1.06-1.11]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.498159618830787	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	11p15.5	11	2670270	KCNQ1	KCNQ1, KCNQ1OT1	NA	NA	ENSG00000053918, ENSG00000269821	NA	NA	rs231361-A	rs231361	0	231361	non_coding_transcript_exon_variant	FALSE	0.285885252458384	1e-9	9	NA	1.09	[1.06-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.285885252458384	1.09	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	11p15.1	11	17387083	KCNJ11	KCNJ11	NA	NA	ENSG00000187486	NA	NA	rs5215-C	rs5215	0	5215	missense_variant	FALSE	0.407702923283646	9e-10	9.045757490560675	NA	1.07	[1.05-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.407702923283646	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	11q13.4	11	72722053	ARAP1	ARAP1	NA	NA	ENSG00000186635	NA	NA	rs1552224-A	rs1552224	0	1552224	5_prime_UTR_variant	FALSE	0.81360202878336	2e-10	9.698970004336019	NA	1.11	[1.07-1.14]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.81360202878336	1.11	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	11q14.3	11	92975544	MTNR1B	MTNR1B	NA	NA	ENSG00000134640	NA	NA	rs10830963-G	rs10830963	0	10830963	intron_variant	FALSE	0.306095573006719	5e-13	12.301029995663981	NA	1.1	[1.07-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.306095573006719	1.1	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	12p13.32	12	4265207	CCND2	CCND2-AS1	NA	NA	ENSG00000255920	NA	NA	rs11063069-G	rs11063069	0	11063069	intron_variant	FALSE	0.214449806025106	3e-7	6.522878745280337	NA	1.08	[1.05-1.11]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.214449806025106	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	12p11.22	12	27812217	KLHDC5	RN7SKP15 - PTHLH	ENSG00000201612	ENSG00000087494	NA	5827	145867	rs10842994-C	rs10842994	0	10842994	intergenic_variant	TRUE	0.80113799137792	6e-10	9.221848749616356	NA	1.1	[1.06-1.13]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.80113799137792	1.1	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	12q14.3	12	65818538	HMGA2	RPSAP52	NA	NA	ENSG00000241749	NA	NA	rs2261181-T	rs2261181	0	2261181	intron_variant	FALSE	0.100953558127083	1e-9	9	NA	1.13	[1.08-1.17]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.100953558127083	1.13	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	12q15	12	71039513	TSPAN8, LGR5	NA - TSPAN8	NA	ENSG00000127324	NA	NA	85572	rs7955901-C	rs7955901	0	7955901	intron_variant	TRUE	0.446519035882972	7e-9	8.154901959985743	NA	1.07	[1.05-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.446519035882972	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	12q24.31	12	120989098	HNF1A	HNF1A	NA	NA	ENSG00000135100	NA	NA	rs12427353-G	rs12427353	0	12427353	intron_variant	FALSE	0.794085916842299	7e-8	7.154901959985743	NA	1.08	[1.05-1.12]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.794085916842299	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	13q31.1	13	80143021	SPRY2	LINC01080 - SPRY2	ENSG00000281721	ENSG00000136158	NA	114738	192955	rs1359790-G	rs1359790	0	1359790	intergenic_variant	TRUE	0.718542080796193	1e-8	8	NA	1.08	[1.05-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.718542080796193	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	15q22.2	15	62090956	C2CD4A	NPM1P47 - C2CD4B	ENSG00000259466	ENSG00000205502	NA	7651	72579	rs4502156-T	rs4502156	0	4502156	intergenic_variant	TRUE	0.518359419543052	2e-6	5.698970004336019	NA	1.06	[1.03-1.08]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.518359419543052	1.06	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	15q24.3	15	77540420	HMG20A	HMG20A - LINGO1	ENSG00000140382	ENSG00000169783	NA	54813	72607	rs7177055-A	rs7177055	0	7177055	intergenic_variant	TRUE	0.678861782001094	5e-9	8.301029995663981	NA	1.08	[1.05-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.678861782001094	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	15q26.1	15	91000846	PRC1	VPS33B	NA	NA	ENSG00000184056	NA	NA	rs12899811-G	rs12899811	0	12899811	non_coding_transcript_exon_variant	FALSE	0.309688680465307	6e-9	8.221848749616356	NA	1.08	[1.05-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.309688680465307	1.08	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	16q12.2	16	53785257	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs9936385-C	rs9936385	0	9936385	intron_variant	FALSE	0.408448080917121	3e-23	22.522878745280337	NA	1.13	[1.10-1.16]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.408448080917121	1.13	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	16q23.1	16	75213347	BCAR1	CTRB2 - CTRB1	ENSG00000284810	ENSG00000285346	NA	6186	5641	rs7202877-T	rs7202877	0	7202877	intergenic_variant	TRUE	0.890915967077822	4e-8	7.3979400086720375	NA	1.12	[1.07-1.16]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.890915967077822	1.12	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	17q12	17	37742390	HNF1B	HNF1B, HNF1B	NA	NA	ENSG00000276194, ENSG00000275410	NA	NA	rs11651052-A	rs11651052	0	11651052	intron_variant	FALSE	0.444815275802543	2e-11	10.698970004336019	NA	1.1	[1.07-1.14]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.444815275802543	1.1	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	18q21.32	18	60381959	MC4R	MC4R - NA	ENSG00000166603	NA	NA	9184	NA	rs11873305-A	rs11873305	0	11873305	intron_variant	TRUE	0.959771168150773	4e-7	6.3979400086720375	NA	1.18	[1.11-1.26]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.959771168150773	1.18	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	19q13.32	19	45655255	GIPR	RN7SL836P - GIPR	ENSG00000241226	ENSG00000010310	NA	3450	12966	rs8108269-G	rs8108269	0	8108269	intergenic_variant	TRUE	0.31074111685129	4e-7	6.3979400086720375	NA	1.07	[1.04-1.10]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.31074111685129	1.07	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	19p13.11	19	19296909	CILP2	SUGP1	NA	NA	ENSG00000105705	NA	NA	rs10401969-C	rs10401969	0	10401969	intron_variant	FALSE	0.080536977769365	7e-9	8.154901959985743	NA	1.13	[1.09-1.18]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.080536977769365	1.13	NA
2017-12-11	22885922	Morris AP	2012-09-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Type 2 diabetes	6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls	12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls	18q21.32	18	60217517	MC4R	RNU4-17P - NA	ENSG00000202468	NA	NA	53810	NA	rs12970134-A	rs12970134	0	12970134	intergenic_variant	TRUE	0.270057407439791	1e-8	8	NA	1.08	[1.05-1.11]	Affymetrix, Illumina [up to 2500000] (imputed)	N	type II diabetes mellitus	http://www.ebi.ac.uk/efo/EFO_0001360	GCST005047	Genome-wide genotyping array	0.270057407439791	1.08	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry colorectal cancer cases, 636 Austrian ancestry advanced colorectal adenoma cases, , 855 Austrian ancestry controls	NA	16q23.1	16	78592686	WWOX	WWOX	NA	NA	ENSG00000186153	NA	NA	rs1912804-?	rs1912804	0	1912804	intron_variant	FALSE	NA	1e-6	6	NA	1.586	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005148	Genome-wide genotyping array	NA	1.586	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry colorectal cancer cases, 636 Austrian ancestry advanced colorectal adenoma cases, , 855 Austrian ancestry controls	NA	1p21.2	1	101777361	Intergenic	LINC01709	NA	NA	ENSG00000226715	NA	NA	rs6668441-?	rs6668441	0	6668441	intron_variant	FALSE	NA	5e-6	5.301029995663981	NA	1.9264112	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005148	Genome-wide genotyping array	NA	1.9264112	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry colorectal cancer cases, 636 Austrian ancestry advanced colorectal adenoma cases, , 855 Austrian ancestry controls	NA	18p11.21	18	13954110	Intergenic	MC2R - NA	ENSG00000185231	NA	NA	38403	NA	rs35505947-?	rs35505947	0	35505947	intergenic_variant	TRUE	NA	6e-6	5.221848749616356	NA	1.460707	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005148	Genome-wide genotyping array	NA	1.460707	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry colorectal cancer cases, 636 Austrian ancestry advanced colorectal adenoma cases, , 855 Austrian ancestry controls	NA	7q21.11	7	82357973	Intergenic	CACNA2D1	NA	NA	ENSG00000153956	NA	NA	rs17179503-?	rs17179503	0	17179503	intron_variant	FALSE	NA	6e-6	5.221848749616356	NA	1.8409425	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005148	Genome-wide genotyping array	NA	1.8409425	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry colorectal cancer cases, 636 Austrian ancestry advanced colorectal adenoma cases, , 855 Austrian ancestry controls	NA	8q24.21	8	128126960	Intergenic	PVT1	NA	NA	ENSG00000249859	NA	NA	rs17382698-?	rs17382698	0	17382698	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	1.522	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005148	Genome-wide genotyping array	NA	1.522	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry colorectal cancer cases, 636 Austrian ancestry advanced colorectal adenoma cases, , 855 Austrian ancestry controls	NA	6p12.1	6	54865546	Intergenic	FAM83B	NA	NA	ENSG00000168143	NA	NA	rs1155750-?	rs1155750	0	1155750	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	1.4334862	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005148	Genome-wide genotyping array	NA	1.4334862	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	11q24.2	11	127775792	Intergenic	SLC25A47P1 - NA	ENSG00000254799	NA	NA	68511990	NA	rs10790917-?	rs10790917	0	10790917	intergenic_variant	TRUE	NA	2e-6	5.698970004336019	NA	1.2884938	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.2884938	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	11q22.1	11	101538407	Intergenic	TRPC6	NA	NA	ENSG00000137672	NA	NA	rs11224824-?	rs11224824	0	11224824	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	1.436	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.436	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	3p14.3	3	58566602	Intergenic	FAM107A	NA	NA	ENSG00000168309	NA	NA	rs11539086-?	rs11539086	0	11539086	missense_variant	FALSE	NA	9e-6	5.045757490560675	NA	1.522	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.522	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	1p36.21	1	14338636	Intergenic	KAZN	NA	NA	ENSG00000189337	NA	NA	rs11803759-?	rs11803759	0	11803759	intron_variant	FALSE	NA	6e-6	5.221848749616356	NA	1.851	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.851	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	15q25.3	15	87509536	Intergenic	RNU6-185P - LINC00052	ENSG00000207150	ENSG00000259527	NA	35247	67393	rs11853542-?	rs11853542	0	11853542	intron_variant	TRUE	NA	7e-6	5.154901959985743	NA	1.36	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.36	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	3p11.1	3	88708681	C3orf38	NA	NA	NA	NA	NA	NA	rs11927424-?	rs11927424	0	11927424	intergenic_variant	TRUE	NA	1e-6	6	NA	1.307	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.307	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	1q42.2	1	230811394	Intergenic	CAPN9 - RNA5SP79	ENSG00000135773	ENSG00000202063	NA	9391	8856	rs1202519-?	rs1202519	0	1202519	intergenic_variant	TRUE	NA	6e-6	5.221848749616356	NA	1.2845215	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.2845215	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	4p14	4	39618250	Intergenic	SMIM14	NA	NA	ENSG00000163683	NA	NA	rs12500234-?	rs12500234	0	12500234	non_coding_transcript_exon_variant	FALSE	NA	4e-6	5.3979400086720375	NA	1.2956724	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.2956724	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	18q21.2	18	55287190	Intergenic	TCF4	NA	NA	ENSG00000196628	NA	NA	rs1262463-?	rs1262463	0	1262463	intron_variant	FALSE	NA	5e-6	5.301029995663981	NA	1.595	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.595	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	7p22.1	7	5094305	Intergenic	RBAKDN - OR10AH1P	ENSG00000273313	ENSG00000272595	NA	21082	9414	rs12667108-?	rs12667108	0	12667108	intergenic_variant	TRUE	NA	6e-6	5.221848749616356	NA	1.459641	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.459641	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	7q36.3	7	157662767	Intergenic	PTPRN2, PTPRN2	NA	NA	ENSG00000282185, ENSG00000155093	NA	NA	rs1270639-?	rs1270639	0	1270639	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	1.437	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.437	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	15q13.1	15	28165345	HERC2	HERC2, HERC2	NA	NA	ENSG00000276802, ENSG00000128731	NA	NA	rs12916300-?	rs12916300	0	12916300	intron_variant	FALSE	NA	4e-7	6.3979400086720375	NA	1.35	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.35	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	18q21.1	18	48927559	SMAD7	SMAD7	NA	NA	ENSG00000101665	NA	NA	rs12953717-?	rs12953717	0	12953717	intron_variant	FALSE	NA	9e-7	6.045757490560675	NA	1.302	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.302	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	2q11.2	2	97707918	Intergenic	C2orf92 - ZAP70	ENSG00000228486	ENSG00000115085	NA	4854	5658	rs12999616-?	rs12999616	0	12999616	regulatory_region_variant	TRUE	NA	7e-6	5.154901959985743	NA	1.338	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.338	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	5p15.31	5	7983139	Intergenic	RNU1-76P - SPEF2	ENSG00000199773	ENSG00000152582	NA	2835	27634705	rs13170463-?	rs13170463	0	13170463	intergenic_variant	TRUE	NA	5e-6	5.301029995663981	NA	1.667	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.667	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	6p22.1	6	29723242	Intergenic	HLA-F, HLA-F, HLA-F, HLA-F, HLA-F, HLA-F, HLA-F	NA	NA	ENSG00000235220, ENSG00000204642, ENSG00000137403, ENSG00000237508, ENSG00000234487, ENSG00000229698, ENSG00000206509	NA	NA	rs1362126-?	rs1362126	0	1362126	non_coding_transcript_exon_variant	FALSE	NA	3e-7	6.522878745280337	NA	1.3908206	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.3908206	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	10q26.13	10	123487946	Intergenic	LINC02641	NA	NA	ENSG00000230131	NA	NA	rs1557614-?	rs1557614	0	1557614	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	1.292992	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.292992	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	3q13.2	3	113409144	WDR52	CFAP44, CFAP44-AS1	NA	NA	ENSG00000206530, ENSG00000243849	NA	NA	rs16845107-?	rs16845107	0	16845107	missense_variant	FALSE	NA	6e-7	6.221848749616356	NA	1.9069412	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.9069412	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	4p15.31	4	20778692	KCNIP4	KCNIP4	NA	NA	ENSG00000185774	NA	NA	rs16869961-?	rs16869961	0	16869961	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	1.3287271	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.3287271	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	15q26.1	15	90595866	CRTC3	CRTC3	NA	NA	ENSG00000140577	NA	NA	rs16944613-?	rs16944613	0	16944613	non_coding_transcript_exon_variant	FALSE	NA	2e-6	5.698970004336019	NA	1.343	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.343	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	14q13.3	14	36888207	Intergenic	SLC25A21	NA	NA	ENSG00000183032	NA	NA	rs17177725-?	rs17177725	0	17177725	intron_variant	FALSE	NA	8e-6	5.096910013008056	NA	1.6447369	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.6447369	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	5p13.3	5	31804244	Intergenic	PDZD2	NA	NA	ENSG00000133401	NA	NA	rs17416314-?	rs17416314	0	17416314	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	1.6490766	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.6490766	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	3p21.2	3	50713718	DOCK3	DOCK3	NA	NA	ENSG00000088538	NA	NA	rs17659990-?	rs17659990	0	17659990	intron_variant	FALSE	NA	1e-7	7	NA	1.925	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.925	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	1q43	1	239918447	CHRM3	CHRM3 - RPS7P5	ENSG00000133019	ENSG00000217327	NA	2995	94199	rs2184857-?	rs2184857	0	2184857	intergenic_variant	TRUE	NA	6e-6	5.221848749616356	NA	1.2934936	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.2934936	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	19q13.11	19	34277685	Intergenic	GARRE1, GARRE1	NA	NA	ENSG00000166398, ENSG00000279389	NA	NA	rs28541881-?	rs28541881	0	28541881	intron_variant	FALSE	NA	1e-6	6	NA	1.604	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.604	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	19q13.11	19	34426795	Intergenic	PDCD2L - UBA2	ENSG00000126249	ENSG00000126261	NA	627	1557	rs2965280-?	rs2965280	0	2965280	intron_variant	TRUE	NA	2e-6	5.698970004336019	NA	1.606	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.606	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	12p11.22	12	29797945	Intergenic	TMTC1 - NA	ENSG00000133687	NA	NA	13186	NA	rs302359-?	rs302359	0	302359	regulatory_region_variant	TRUE	NA	3e-6	5.522878745280337	NA	2.471	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	2.471	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	13q33.2	13	104707293	Intergenic	NA	NA	NA	NA	NA	NA	rs323473-?	rs323473	0	323473	intergenic_variant	TRUE	NA	4e-6	5.3979400086720375	NA	1.578	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.578	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	16p12.1	16	26527941	Intergenic	NA - LINC02195	NA	ENSG00000236481	NA	NA	56814	rs35874699-?	rs35874699	0	35874699	intergenic_variant	TRUE	NA	5e-6	5.301029995663981	NA	1.2886598	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.2886598	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	3q26.31	3	171840746	Intergenic	TMEM212-AS1	NA	NA	ENSG00000234717	NA	NA	rs3914272-?	rs3914272	0	3914272	intron_variant	FALSE	NA	5e-6	5.301029995663981	NA	1.38	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.38	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	11p14.3	11	25990646	Intergenic	NA	NA	NA	NA	NA	NA	rs4086865-?	rs4086865	0	4086865	intergenic_variant	TRUE	NA	7e-6	5.154901959985743	NA	1.665	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.665	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	13q31.1	13	84504393	Intergenic	PCDH17 - MTND4P1	ENSG00000118946	ENSG00000228597	NA	26775082	15710	rs4397989-?	rs4397989	0	4397989	intergenic_variant	TRUE	NA	3e-6	5.522878745280337	NA	1.3208295	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.3208295	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	9q33.2	9	122511295	Intergenic	OR1J2	NA	NA	ENSG00000197233	NA	NA	rs4836891-?	rs4836891	0	4836891	missense_variant	FALSE	NA	9e-7	6.045757490560675	NA	1.582	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.582	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	9q33.1	9	115006400	Intergenic	DELEC1	NA	NA	ENSG00000173077	NA	NA	rs4979489-?	rs4979489	0	4979489	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	1.3310263	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.3310263	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	13q13.3	13	36848378	Intergenic	SMAD9	NA	NA	ENSG00000120693	NA	NA	rs511674-?	rs511674	0	511674	3_prime_UTR_variant	FALSE	NA	6e-6	5.221848749616356	NA	2.155	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	2.155	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	22q12.2	22	31442532	Intergenic	EIF4ENIF1, DRG1	NA	NA	ENSG00000184708, ENSG00000185721	NA	NA	rs5753618-?	rs5753618	0	5753618	intron_variant	FALSE	NA	6e-7	6.221848749616356	NA	1.366	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.366	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	18p11.22	18	9701785	Intergenic	KRT18P8 - RAB31	ENSG00000264644	ENSG00000168461	NA	22292	6490	rs674617-?	rs674617	0	674617	intergenic_variant	TRUE	NA	9e-6	5.045757490560675	NA	1.486	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.486	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	4q21.22	4	81772382	Intergenic	RASGEF1B	NA	NA	ENSG00000138670	NA	NA	rs6853410-?	rs6853410	0	6853410	intron_variant	FALSE	NA	7e-6	5.154901959985743	NA	1.315	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.315	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	18q22.3	18	72554745	CBLN2	CBLN2	NA	NA	ENSG00000141668	NA	NA	rs694339-?	rs694339	0	694339	intron_variant	FALSE	NA	1e-7	7	NA	1.973	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.973	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	2q37.2	2	234701030	Intergenic	LINC01173	NA	NA	ENSG00000280744	NA	NA	rs7606512-?	rs7606512	0	7606512	intron_variant	FALSE	NA	9e-7	6.045757490560675	NA	1.837	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.837	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	22q12.2	22	30743331	Intergenic	OSBP2	NA	NA	ENSG00000184792	NA	NA	rs926340-?	rs926340	0	926340	intron_variant	FALSE	NA	8e-6	5.096910013008056	NA	1.274	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.274	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry cases, 4,294 European ancestry controls	NA	19q13.43	19	57067709	Intergenic	RPL7AP69 - USP29	ENSG00000268483	ENSG00000131864	NA	1570	51429	rs9676308-?	rs9676308	0	9676308	intergenic_variant	TRUE	NA	9e-6	5.045757490560675	NA	1.643	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005149	Genome-wide genotyping array	NA	1.643	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry colorectal cancer cases, 636 Austrian ancestry advanced colorectal adenoma cases, 4,294 European ancestry controls	NA	22q12.2	22	30743331	Intergenic	OSBP2	NA	NA	ENSG00000184792	NA	NA	rs926340-?	rs926340	0	926340	intron_variant	FALSE	NA	4e-6	5.3979400086720375	NA	1.235	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005150	Genome-wide genotyping array	NA	1.235	NA
2018-01-15	29228715	Hofer P	2017-10-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/29228715	Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.	Colorectal cancer	978 Austrian ancestry colorectal cancer cases, 636 Austrian ancestry advanced colorectal adenoma cases, 4,294 European ancestry controls	NA	22q12.2	22	31442532	Intergenic	EIF4ENIF1, DRG1	NA	NA	ENSG00000184708, ENSG00000185721	NA	NA	rs5753618-?	rs5753618	0	5753618	intron_variant	FALSE	NA	8e-6	5.096910013008056	NA	1.274	[NR]	Affymetrix [492217] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST005150	Genome-wide genotyping array	NA	1.274	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	21q22.3	21	45307222	NR	LINC00315 - LINC00316; No mapped genes	NA	NA	NA	NA	NA	rs2838871-G; rs2838869-A	rs2838871; rs2838869	0	NA	intergenic_variant; intron_variant	NA	0.161	1e-8	8	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.161	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	21q22.3	21	45307222	NR	LINC00315 - LINC00316; No mapped genes	NA	NA	NA	NA	NA	rs2838871-G; rs2838869-G	rs2838871; rs2838869	0	NA	intergenic_variant; intron_variant	NA	0.05	3e-7	6.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.05	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	21q22.3	21	45463239	NR	COL18A1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4819119-A; rs2236461-T; rs10854470-C; rs2838932-C; rs2838925-C; rs8126650-T; rs11911327-C; rs2838933-T; rs2236458-C	rs4819119; rs2236461; rs10854470; rs2838932; rs2838925; rs8126650; rs11911327; rs2838933; rs2236458	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.003	3e-8	7.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.003	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	21q22.3	21	45844416	NR	PCBP3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11911016-A; rs8127428-C; rs4819157-T; rs17351433-A; rs12481867-A; rs2839014-A; rs2839020-G; rs2150453-G; rs2839015-G; rs16978629-G; rs11910741-G	rs11911016; rs8127428; rs4819157; rs17351433; rs12481867; rs2839014; rs2839020; rs2150453; rs2839015; rs16978629; rs11910741	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant	NA	0.001	6e-14	13.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.001	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	21q22.3	21	45844416	NR	PCBP3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11911016-A; rs8127428-C; rs4819157-T; rs17351433-A; rs12481867-A; rs2839014-G; rs2839020-G; rs2150453-G; rs2839015-G; rs16978629-G; rs11910741-G	rs11911016; rs8127428; rs4819157; rs17351433; rs12481867; rs2839014; rs2839020; rs2150453; rs2839015; rs16978629; rs11910741	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant	NA	0.161	4e-7	6.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.161	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	22q11.1	22	17203454	NR	ADA2; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2231489-C; rs1076106-C; rs1076105-G; rs2240617-A	rs2231489; rs1076106; rs1076105; rs2240617	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.107	9e-6	5.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.107	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	NA	NA	NA	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs174301-C; rs174297-C; rs4452253-T; rs78914-G; rs4819596-A; rs13053400-G; rs5747211-G	rs174301; rs174297; rs4452253; rs78914; rs4819596; rs13053400; rs5747211	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; missense_variant	NA	0.014	9e-13	12.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.014	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	NA	NA	NA	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs174301-T; rs174297-C; rs4452253-T; rs78914-G; rs4819596-A; rs13053400-G; rs5747211-G	rs174301; rs174297; rs4452253; rs78914; rs4819596; rs13053400; rs5747211	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; missense_variant	NA	0.161	3e-9	8.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.161	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	22q11.21	22	17763609	NR	BID; No mapped genes	NA	NA	NA	NA	NA	rs5747351-G; rs5746474-T	rs5747351; rs5746474	0	NA	intron_variant; intron_variant	NA	0.006	3e-34	33.52287874528034	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.006	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	22q11.21	22	17763609	NR	BID; No mapped genes	NA	NA	NA	NA	NA	rs5747351-G; rs5746474-C	rs5747351; rs5746474	0	NA	intron_variant; intron_variant	NA	0.392	5e-20	19.30102999566398	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.392	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q12.12	13	23030027	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10507321-G; rs17285225-T; rs7337589-C; rs12428629-G; rs9317421-C; rs17357143-T; rs3887157-G; rs17357567-A	rs10507321; rs17285225; rs7337589; rs12428629; rs9317421; rs17357143; rs3887157; rs17357567	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q12.12	13	23170240	NR	LINC00362; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs9507041-C; rs9552866-G; rs574662-A; rs9510610-T; rs597425-T; rs529154-C	rs9507041; rs9552866; rs574662; rs9510610; rs597425; rs529154	0	NA	intron_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	2e-11	10.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q12.12	13	23188133	NR	SGCG; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs578196-A; rs501909-A; rs502068-G	rs578196; rs501909; rs502068	0	NA	intron_variant; intron_variant; intron_variant	NA	0.001	7e-19	18.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.001	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q12.12	13	23188133	NR	SGCG; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs578196-G; rs501909-A; rs502068-G	rs578196; rs501909; rs502068	0	NA	intron_variant; intron_variant; intron_variant	NA	0.3	2e-15	14.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.3	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q12.13	13	25186475	NR	LINC01053; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs17081893-C; rs17081882-C; rs9578831-C; rs12428981-C	rs17081893; rs17081882; rs9578831; rs12428981	0	NA	intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant	NA	0.055	3e-6	5.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.055	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q12.13	13	25725676	NR	ATP8A2; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs3132364-A; rs9553651-T; rs3117849-G; rs3117848-G	rs3132364; rs9553651; rs3117849; rs3117848	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.157	1e-7	7	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.157	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q12.13	13	25725676	NR	ATP8A2; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs3132364-A; rs9553651-C; rs3117849-G; rs3117848-G	rs3132364; rs9553651; rs3117849; rs3117848	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.773	5e-6	5.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.773	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q12.2	13	27637171	NR	POLR1D; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12584838-G; rs9551373-T; rs531950-C; rs10492484-A; rs7337722-G; rs667374-G; rs12876263-T; rs12870355-T; rs17821569-C; rs9507915-A; rs634035-A; rs542610-T; rs6491221-A; rs12050009-A	rs12584838; rs9551373; rs531950; rs10492484; rs7337722; rs667374; rs12876263; rs12870355; rs17821569; rs9507915; rs634035; rs542610; rs6491221; rs12050009	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant	NA	0.136	2e-8	7.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.136	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q12.2	13	27637171	NR	POLR1D; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12584838-G; rs9551373-T; rs531950-C; rs10492484-A; rs7337722-G; rs667374-G; rs12876263-T; rs12870355-T; rs17821569-C; rs9507915-A; rs634035-A; rs542610-T; rs6491221-C; rs12050009-A	rs12584838; rs9551373; rs531950; rs10492484; rs7337722; rs667374; rs12876263; rs12870355; rs17821569; rs9507915; rs634035; rs542610; rs6491221; rs12050009	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant	NA	0.005	7e-7	6.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.005	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q12.3	13;13	28318755;28318584	NR	FLT1; FLT1	NA	NA	NA	NA	NA	rs3794399-T; rs3794397-C	rs3794399; rs3794397	0	NA	intron_variant; intron_variant	NA	0.114	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.114	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q13.3	13	35766000	NR	LINC00445 - DCLK1; No mapped genes	NA	NA	NA	NA	NA	rs11843245-C; rs7326597-A	rs11843245; rs7326597	0	NA	regulatory_region_variant; intergenic_variant	NA	0.574	8e-8	7.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.574	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q13.3	13	35766000	NR	LINC00445 - DCLK1; No mapped genes	NA	NA	NA	NA	NA	rs11843245-C; rs7326597-G	rs11843245; rs7326597	0	NA	regulatory_region_variant; intergenic_variant	NA	0.286	2e-7	6.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.286	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q13.3	13	35924961	NR	DCLK1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1171052-C; rs1171072-T; rs1171092-C; rs9574926-A; rs9593571-C; rs7358881-T; rs7319248-T; rs9565689-A; rs1171091-G	rs1171052; rs1171072; rs1171092; rs9574926; rs9593571; rs7358881; rs7319248; rs9565689; rs1171091	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	1e-6	6	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q13.3	13	38959453	NR	ANKRD26P2 - STOML3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7985783-A; rs7984412-A; rs17058847-G; rs4448804-A; rs9315638-G; rs7330041-A; rs7330236-A; rs9548569-C; rs10492692-C; rs10492690-C; rs17058855-G; rs6563655-G; rs9548568-A; rs17058858-C; rs9603485-G; rs7327384-A; rs13378699-A; rs4281582-T; rs7985312-G; rs9576663-A	rs7985783; rs7984412; rs17058847; rs4448804; rs9315638; rs7330041; rs7330236; rs9548569; rs10492692; rs10492690; rs17058855; rs6563655; rs9548568; rs17058858; rs9603485; rs7327384; rs13378699; rs4281582; rs7985312; rs9576663	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	1e-20	20	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	13q13.3	13	38959453	NR	ANKRD26P2 - STOML3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7985783-A; rs7984412-A; rs17058847-G; rs4448804-A; rs9315638-G; rs7330041-A; rs7330236-A; rs9548569-C; rs10492692-C; rs10492690-T; rs17058855-G; rs6563655-G; rs9548568-A; rs17058858-C; rs9603485-G; rs7327384-A; rs13378699-A; rs4281582-T; rs7985312-G; rs9576663-A	rs7985783; rs7984412; rs17058847; rs4448804; rs9315638; rs7330041; rs7330236; rs9548569; rs10492692; rs10492690; rs17058855; rs6563655; rs9548568; rs17058858; rs9603485; rs7327384; rs13378699; rs4281582; rs7985312; rs9576663	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.249	6e-14	13.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.249	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	5q15	5	96734501	CAST	CAST	NA	NA	ENSG00000153113	NA	NA	rs149313-T	rs149313	0	149313	intron_variant	FALSE	0.4708543	4e-33	32.39794000867204	(Endoplasmic reticulum aminopeptidase 1)	0.5227	[0.44-0.61] unit increase	Affymetrix [509946]	N	endoplasmic reticulum aminopeptidase 1 measurement	http://www.ebi.ac.uk/efo/EFO_0008119	GCST004365	Genome-wide genotyping array	0.4708543	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4q35.2	4	186229652	KLKB1	KLKB1	NA	NA	ENSG00000164344	NA	NA	rs1511802-C	rs1511802	0	1511802	intron_variant	FALSE	0.3704819	9e-29	28.045757490560675	(Plasma kallikrein)	0.4755	[0.39-0.56] unit increase	Affymetrix [509946]	N	plasma kallikrein measurement	http://www.ebi.ac.uk/efo/EFO_0008260	GCST004365	Genome-wide genotyping array	0.3704819	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4q13.3	4	73893084	CXCL1, HNRNPA1P55, CXCL1P	CXCL1 - HNRNPA1P55	ENSG00000163739	ENSG00000249920	NA	21776	45520	rs16845091-T	rs16845091	0	16845091	intergenic_variant	TRUE	0.05466399	2e-39	38.69897000433602	(Growth-regulated alpha protein)	1.237	[1.06-1.41] unit increase	Affymetrix [509946]	N	growth-regulated alpha protein measurement	http://www.ebi.ac.uk/efo/EFO_0008146	GCST004365	Genome-wide genotyping array	0.05466399	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4q13.3	4	73838282	CXCL6	CXCL6	NA	NA	ENSG00000124875	NA	NA	rs16850073-T	rs16850073	0	16850073	3_prime_UTR_variant	FALSE	0.3765244	1e-97	97	(C-X-C motif chemokine 6)	0.8877	[0.81-0.96] unit increase	Affymetrix [509946]	N	C-X-C motif chemokine 6 measurement	http://www.ebi.ac.uk/efo/EFO_0008059	GCST004365	Genome-wide genotyping array	0.3765244	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	14q24.3	14	73973416	ENTPD5, CCDC176, ALDH6A1, LIN52, RP5-1021I20.7, RP5-1021I20.4, PTGR2, Y_RNA, RP5-1021I20.8, ZNF410, RP5-1021I20.5, RP5-1021I20.6, FAM161B, COQ6, AC005480.1, RN7SL530P	ENTPD5	NA	NA	ENSG00000187097	NA	NA	rs17094448-G	rs17094448	0	17094448	intron_variant	FALSE	0.06861756	1e-60	60	(Ectonucleoside triphosphate diphosphohydrolase 5)	1.339	[1.19-1.49] unit decrease	Affymetrix [509946]	N	ectonucleoside triphosphate diphosphohydrolase 5 measurement	http://www.ebi.ac.uk/efo/EFO_0008115	GCST004365	Genome-wide genotyping array	0.06861756	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	7q21.11	7	83376946	SEMA3E, AC079987.2	SEMA3E	NA	NA	ENSG00000170381	NA	NA	rs17284969-A	rs17284969	0	17284969	intron_variant	FALSE	0.1220989	2e-65	64.69897000433602	(Semaphorin-3E)	1.072	[0.96-1.19] unit decrease	Affymetrix [509946]	N	semaphorin-3E measurement	http://www.ebi.ac.uk/efo/EFO_0008279	GCST004365	Genome-wide genotyping array	0.1220989	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	16q22.2	16	71934798	IST1, PKD1L3	PKD1L3	NA	NA	ENSG00000277481	NA	NA	rs17286411-G	rs17286411	0	17286411	intron_variant	FALSE	0.3820281	5e-22	21.30102999566398	(Haptoglobin)	0.4404	[0.35-0.53] unit decrease	Affymetrix [509946]	N	haptoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004640	GCST004365	Genome-wide genotyping array	0.3820281	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1p36.13	1	20063829	PLA2G5	PLA2G5	NA	NA	ENSG00000127472	NA	NA	rs17354650-T	rs17354650	0	17354650	intron_variant	FALSE	0.2806225	2e-14	13.698970004336019	(Phospholipase A2, membrane associated)	0.3561	[0.27-0.45] unit increase	Affymetrix [509946]	N	phospholipase A2, membrane associated measurement	http://www.ebi.ac.uk/efo/EFO_0008259	GCST004365	Genome-wide genotyping array	0.2806225	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1p31.3	1	65476583	LEPR, RP4-630A11.3	LEPR	NA	NA	ENSG00000116678	NA	NA	rs17412403-C	rs17412403	0	17412403	intron_variant	FALSE	0.4638917	9e-14	13.045757490560675	(Leptin receptor)	0.3282	[0.24-0.41] unit decrease	Affymetrix [509946]	N	leptin receptor measurement	http://www.ebi.ac.uk/efo/EFO_0004635	GCST004365	Genome-wide genotyping array	0.4638917	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q23.3	1	161675021	FCGR2B, RP11-25K21.1	FCGR2B	NA	NA	ENSG00000072694	NA	NA	rs17413015-T	rs17413015	0	17413015	non_coding_transcript_exon_variant	FALSE	0.1474164	9e-137	136.04575749056067	(Low affinity immunoglobulin gamma Fc region receptor II-a/b)	1.361	[1.27-1.45] unit increase	Affymetrix [509946]	N	low affinity immunoglobulin gamma Fc region receptor II-a/b measurement	http://www.ebi.ac.uk/efo/EFO_0008211	GCST004365	Genome-wide genotyping array	0.1474164	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1p31.3	1	65633330	LEPR	LEPR	NA	NA	ENSG00000116678	NA	NA	rs17415296-A	rs17415296	0	17415296	3_prime_UTR_variant	FALSE	0.1928499	4e-229	228.39794000867204	(Leptin receptor)	1.4	[1.34-1.46] unit decrease	Affymetrix [509946]	N	leptin receptor measurement	http://www.ebi.ac.uk/efo/EFO_0004635	GCST004365	Genome-wide genotyping array	0.1928499	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	5q15	5	96783162	ERAP1, CTD-2260A17.1, CAST, AC008906.1, CTD-2260A17.3, CTD-2260A17.2	ERAP1	NA	NA	ENSG00000164307	NA	NA	rs17482078-T	rs17482078	0	17482078	missense_variant	FALSE	0.1883182	3e-115	114.52287874528034	(Endoplasmic reticulum aminopeptidase 1)	1.142	[1.06-1.23] unit decrease	Affymetrix [509946]	N	endoplasmic reticulum aminopeptidase 1 measurement	http://www.ebi.ac.uk/efo/EFO_0008119	GCST004365	Genome-wide genotyping array	0.1883182	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19q13.41	19	51111898	CTU1	CTU1 - SIGLEC18P	ENSG00000142544	ENSG00000268581	NA	3489	8089	rs17801525-A	rs17801525	0	17801525	regulatory_region_variant	TRUE	0.1108325	4e-12	11.397940008672037	(Sialic acid-binding Ig-like lectin 9)	0.4915	[0.35-0.63] unit decrease	Affymetrix [509946]	N	sialic acid-binding Ig-like lectin 9 measurement	http://www.ebi.ac.uk/efo/EFO_0008286	GCST004365	Genome-wide genotyping array	0.1108325	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4p15.32	4	15662912	FBXL5, CC2D2A, RP11-799M12.2, FAM200B	FBXL5	NA	NA	ENSG00000118564	NA	NA	rs1789-G	rs1789	0	1789	intron_variant	FALSE	0.361809	4e-20	19.397940008672037	(ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2)	0.4142	[0.33-0.5] unit increase	Affymetrix [509946]	N	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 measurement	http://www.ebi.ac.uk/efo/EFO_0008014	GCST004365	Genome-wide genotyping array	0.361809	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	14q11.2	14	20696086	RP11-903H12.5, RNASE4, ANG, RP11-903H12.3	EGILA, ANG, RNASE4	NA	NA	ENSG00000258451, ENSG00000214274, ENSG00000258818	NA	NA	rs1888560-T	rs1888560	0	1888560	intron_variant	FALSE	0.3214644	7e-15	14.154901959985743	(Angiogenin)	0.3446	[0.26-0.43] unit decrease	Affymetrix [509946]	N	angiogenin measurement	http://www.ebi.ac.uk/efo/EFO_0008022	GCST004365	Genome-wide genotyping array	0.3214644	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	11p15.1	11	18259088	SAA1, ST13P5, RNA5SP334	SAA2 - ST13P5	ENSG00000134339	ENSG00000212789	NA	10420	2894	rs1993373-A	rs1993373	0	1993373	intergenic_variant	TRUE	0.3410231	2e-105	104.69897000433602	(Serum amyloid A-1 protein)	0.917	[0.84-0.99] unit increase	Affymetrix [509946]	N	serum amyloid A-1 protein measurement	http://www.ebi.ac.uk/efo/EFO_0008282	GCST004365	Genome-wide genotyping array	0.3410231	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19q13.41	19	51529952	SIGLEC6, SIGLEC27P, CTD-3073N11.9	SIGLEC6	NA	NA	ENSG00000105492	NA	NA	rs2005199-A	rs2005199	0	2005199	missense_variant	FALSE	0.05220884	5e-29	28.30102999566398	(Sialic acid-binding Ig-like lectin 6)	1.102	[0.91-1.29] unit increase	Affymetrix [509946]	N	sialic acid-binding Ig-like lectin 6 measurement	http://www.ebi.ac.uk/efo/EFO_0008285	GCST004365	Genome-wide genotyping array	0.05220884	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	2q12.1	2	102368964	IL18R1, IL1RL1, IL18RAP, AC007278.2, AC007278.3, SLC9A4, AC007248.7, MIR4772	IL18R1	NA	NA	ENSG00000115604	NA	NA	rs2058622-A	rs2058622	0	2058622	intron_variant	FALSE	0.22668	9e-108	107.04575749056067	(Interleukin-18 receptor 1)	0.9953	[0.92-1.07] unit increase	Affymetrix [509946]	N	interleukin 18 receptor 1 measurement	http://www.ebi.ac.uk/efo/EFO_0008178	GCST004365	Genome-wide genotyping array	0.22668	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q12	17	35998496	RP11-104J23.1, CCL15-CCL14, CCL15	CCL15-CCL14, CCL15-CCL14, CCL15, CCL15	NA	NA	ENSG00000275688, ENSG00000282521, ENSG00000275528, ENSG00000275718	NA	NA	rs2075746-T	rs2075746	0	2075746	intron_variant	FALSE	0.4385081	4e-12	11.397940008672037	(C-C motif chemokine 15)	0.2965	[0.21-0.38] unit decrease	Affymetrix [509946]	N	C-C motif chemokine 15 measurement	http://www.ebi.ac.uk/efo/EFO_0008043	GCST004365	Genome-wide genotyping array	0.4385081	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	22q12.3	22	32769034	SYN3	SYN3	NA	NA	ENSG00000185666	NA	NA	rs2097326-G	rs2097326	0	2097326	intron_variant	FALSE	0.2787298	4e-97	96.39794000867204	(Metalloproteinase inhibitor 3)	0.9307	[0.85-1.01] unit increase	Affymetrix [509946]	N	metalloproteinase inhibitor 3 measurement	http://www.ebi.ac.uk/efo/EFO_0008231	GCST004365	Genome-wide genotyping array	0.2787298	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q27.3	3	186677324	HRG, RP11-573D15.8	HRG	NA	NA	ENSG00000113905	NA	NA	rs2228243-G	rs2228243	0	2228243	missense_variant	FALSE	0.2081244	4e-82	81.39794000867204	(Dual specificity mitogen-activated protein kinase kinase 4)	0.9421	[0.85-1.03] unit increase	Affymetrix [509946]	N	dual specificity mitogen-activated protein kinase kinase 4 measurement	http://www.ebi.ac.uk/efo/EFO_0008113	GCST004365	Genome-wide genotyping array	0.2081244	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q27.3	3	186677324	HRG, RP11-573D15.8	HRG	NA	NA	ENSG00000113905	NA	NA	rs2228243-G	rs2228243	0	2228243	missense_variant	FALSE	0.2081244	5e-94	93.30102999566398	(Histidine-rich glycoprotein)	1.007	[0.92-1.09] unit increase	Affymetrix [509946]	N	histidine-rich glycoprotein measurement	http://www.ebi.ac.uk/efo/EFO_0008155	GCST004365	Genome-wide genotyping array	0.2081244	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q11.2	17	28398249	CTB-96E2.3, SARM1, CTB-96E2.6, CTB-96E2.10, VTN, SLC46A1, CTD-2350C19.2, H3F3BP2	SARM1, SLC46A1	NA	NA	ENSG00000004139, ENSG00000076351	NA	NA	rs2239908-G	rs2239908	0	2239908	3_prime_UTR_variant	FALSE	0.459718	3e-24	23.522878745280337	(Calcium/calmodulin-dependent protein kinase type 1D)	0.4461	[0.36-0.53] unit decrease	Affymetrix [509946]	N	calcium/calmodulin-dependent protein kinase type 1D measurement	http://www.ebi.ac.uk/efo/EFO_0008063	GCST004365	Genome-wide genotyping array	0.459718	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q11.2	17	28398249	CTB-96E2.3, SARM1, CTB-96E2.6, CTB-96E2.10, VTN, SLC46A1, CTD-2350C19.2, H3F3BP2	SARM1, SLC46A1	NA	NA	ENSG00000004139, ENSG00000076351	NA	NA	rs2239908-G	rs2239908	0	2239908	3_prime_UTR_variant	FALSE	0.459718	9e-48	47.045757490560675	(Semaphorin-3A)	0.6172	[0.54-0.7] unit decrease	Affymetrix [509946]	N	semaphorin-3A measurement	http://www.ebi.ac.uk/efo/EFO_0008278	GCST004365	Genome-wide genotyping array	0.459718	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	6p21.33	6	31960914	CYP21A2, NELFE, DXO, TNXB, C2, C2-AS1, XXbac-BPG116M5.17, CFB, MIR1236, SKIV2L, STK19, C4A, C4B, C4B-AS1, RNA5SP206	SKIV2L, SKIV2L, SKIV2L, SKIV2L, SKIV2L, SKIV2L	NA	NA	ENSG00000232616, ENSG00000228896, ENSG00000225737, ENSG00000204351, ENSG00000206353, ENSG00000223493	NA	NA	rs2280774-A	rs2280774	0	2280774	intron_variant	FALSE	0.3705942	8e-29	28.096910013008056	(Complement C4b)	0.5048	[0.42-0.59] unit decrease	Affymetrix [509946]	N	complement C4b measurement	http://www.ebi.ac.uk/efo/EFO_0008092	GCST004365	Genome-wide genotyping array	0.3705942	NA	NA
2017-11-28	29066090	Allen RJ	2017-10-20	Lancet Respir Med	www.ncbi.nlm.nih.gov/pubmed/29066090	Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.	Idiopathic pulmonary fibrosis	602 European ancestry cases, 3,366 European ancestry controls	2,158 cases, 5,195 controls	2p23.1	2	31561411	SRD5A2	SRD5A2	NA	NA	ENSG00000277893	NA	NA	rs191031841-T	rs191031841	0	191031841	intron_variant	FALSE	0.041	6e-6	5.221848749616356	NA	1.73	[1.36-2.18]	Affymetrix [NR] (imputed)	N	idiopathic pulmonary fibrosis	http://www.ebi.ac.uk/efo/EFO_0000768	GCST004986	Genome-wide genotyping array	0.041	1.73	NA
2017-11-28	29066090	Allen RJ	2017-10-20	Lancet Respir Med	www.ncbi.nlm.nih.gov/pubmed/29066090	Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.	Idiopathic pulmonary fibrosis	602 European ancestry cases, 3,366 European ancestry controls	2,158 cases, 5,195 controls	4q22.1	4	89655739	Intergenic	NA - SNCA	NA	ENSG00000145335	NA	NA	44606	rs28673968-T	rs28673968	0	28673968	intron_variant	TRUE	0.877	1e-7	7	NA	1.2658228	[1.16-1.39]	Affymetrix [NR] (imputed)	N	idiopathic pulmonary fibrosis	http://www.ebi.ac.uk/efo/EFO_0000768	GCST004986	Genome-wide genotyping array	0.877	1.2658228	NA
2017-11-28	29066090	Allen RJ	2017-10-20	Lancet Respir Med	www.ncbi.nlm.nih.gov/pubmed/29066090	Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.	Idiopathic pulmonary fibrosis	602 European ancestry cases, 3,366 European ancestry controls	2,158 cases, 5,195 controls	6p24.3	6	7562999	DSP	DSP	NA	NA	ENSG00000096696	NA	NA	rs2076295-G	rs2076295	0	2076295	intron_variant	FALSE	0.463	8e-28	27.096910013008056	NA	1.44	[1.35-1.54]	Affymetrix [NR] (imputed)	N	idiopathic pulmonary fibrosis	http://www.ebi.ac.uk/efo/EFO_0000768	GCST004986	Genome-wide genotyping array	0.463	1.44	NA
2017-11-28	29066090	Allen RJ	2017-10-20	Lancet Respir Med	www.ncbi.nlm.nih.gov/pubmed/29066090	Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.	Idiopathic pulmonary fibrosis	602 European ancestry cases, 3,366 European ancestry controls	2,158 cases, 5,195 controls	NA	NA	NA	MRPL13	NA	NA	NA	NA	NA	NA	chr8:121446432-T	chr8:121446432	0	NA	NA	TRUE	0.03	2e-7	6.698970004336019	NA	15.9	[5.61-45.0]	Affymetrix [NR] (imputed)	N	idiopathic pulmonary fibrosis	http://www.ebi.ac.uk/efo/EFO_0000768	GCST004986	Genome-wide genotyping array	0.03	15.9	NA
2017-11-28	29066090	Allen RJ	2017-10-20	Lancet Respir Med	www.ncbi.nlm.nih.gov/pubmed/29066090	Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.	Idiopathic pulmonary fibrosis	602 European ancestry cases, 3,366 European ancestry controls	2,158 cases, 5,195 controls	11p15.5	11	1219991	MUC5B	MUC5AC - MUC5B	ENSG00000283158	ENSG00000117983	NA	18853	3075	rs35705950-T	rs35705950	0	35705950	splice_region_variant	TRUE	0.143	1e-66	66	NA	2.89	[2.56-3.26]	Affymetrix [NR] (imputed)	N	idiopathic pulmonary fibrosis	http://www.ebi.ac.uk/efo/EFO_0000768	GCST004986	Genome-wide genotyping array	0.143	2.89	NA
2017-11-28	29066090	Allen RJ	2017-10-20	Lancet Respir Med	www.ncbi.nlm.nih.gov/pubmed/29066090	Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.	Idiopathic pulmonary fibrosis	602 European ancestry cases, 3,366 European ancestry controls	2,158 cases, 5,195 controls	15q25.3	15	85756967	AKAP13, KLHL25	LINC02883 - KLHL25	ENSG00000259416	ENSG00000183655	NA	730	2359	rs62025270-A	rs62025270	0	62025270	regulatory_region_variant	TRUE	0.247	1e-9	9	NA	1.27	[1.18-1.37]	Affymetrix [NR] (imputed)	N	idiopathic pulmonary fibrosis	http://www.ebi.ac.uk/efo/EFO_0000768	GCST004986	Genome-wide genotyping array	0.247	1.27	NA
2017-11-28	29066090	Allen RJ	2017-10-20	Lancet Respir Med	www.ncbi.nlm.nih.gov/pubmed/29066090	Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.	Idiopathic pulmonary fibrosis	602 European ancestry cases, 3,366 European ancestry controls	2,158 cases, 5,195 controls	17q21.32	17	46930382	GOSR2	GOSR2	NA	NA	ENSG00000108433	NA	NA	rs117791180-T	rs117791180	0	117791180	non_coding_transcript_exon_variant	FALSE	0.034	4e-6	5.3979400086720375	NA	2.04	[1.51-2.77]	Affymetrix [NR] (imputed)	N	idiopathic pulmonary fibrosis	http://www.ebi.ac.uk/efo/EFO_0000768	GCST004986	Genome-wide genotyping array	0.034	2.04	NA
2017-11-28	29066090	Allen RJ	2017-10-20	Lancet Respir Med	www.ncbi.nlm.nih.gov/pubmed/29066090	Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.	Idiopathic pulmonary fibrosis	602 European ancestry cases, 3,366 European ancestry controls	2,158 cases, 5,195 controls	19q13.42	19	54420809	TTYH1	TTYH1	NA	NA	ENSG00000276537	NA	NA	rs73606754-C	rs73606754	0	73606754	splice_region_variant	FALSE	0.863	3e-9	8.522878745280337	NA	1.5384616	[1.33-1.75]	Affymetrix [NR] (imputed)	N	idiopathic pulmonary fibrosis	http://www.ebi.ac.uk/efo/EFO_0000768	GCST004986	Genome-wide genotyping array	0.863	1.5384616	NA
2018-02-13	29374233	Lu AT	2018-01-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29374233	GWAS of epigenetic aging rates in blood reveals a critical role for TERT.	Extrinsic epigenetic age acceleration	8,393 European ancestry individuals	1,023 African American individuals, 491 Hispanic individuals	4p16.3	4	2750698	TNIP2	TNIP2	NA	NA	ENSG00000168884	NA	NA	rs10937913-A	rs10937913	0	10937913	intron_variant	FALSE	0.46	2e-11	10.698970004336019	NA	0.5913	[0.42-0.76] unit decrease	Affymetrix, Illumina [~ 7400000] (imputed)	N	aging	http://purl.obolibrary.org/obo/GO_0007568	GCST005288	Genome-wide genotyping array	0.46	NA	0.5913
2018-02-13	29374233	Lu AT	2018-01-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29374233	GWAS of epigenetic aging rates in blood reveals a critical role for TERT.	Extrinsic epigenetic age acceleration	8,393 European ancestry individuals	1,023 African American individuals, 491 Hispanic individuals	10p11.21	10	37681918	ANKRD30A, ZNF248	MTRNR2L7 - ZNF248	ENSG00000256892	ENSG00000198105	NA	78944	94608	rs71007656-C	rs71007656	0	71007656	intergenic_variant	TRUE	0.49	7e-11	10.154901959985743	NA	0.5914	[0.41-0.77] unit increase	Affymetrix, Illumina [~ 7400000] (imputed)	N	aging	http://purl.obolibrary.org/obo/GO_0007568	GCST005288	Genome-wide genotyping array	0.49	NA	0.5914
2018-02-13	29374233	Lu AT	2018-01-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29374233	GWAS of epigenetic aging rates in blood reveals a critical role for TERT.	Extrinsic epigenetic age acceleration	8,393 European ancestry individuals	1,023 African American individuals, 491 Hispanic individuals	10p11.21	10	37929331	ZNF248, ZNF25	ZNF33CP - ZNF25	ENSG00000235197	ENSG00000175395	NA	32665	20242	rs1005277-A	rs1005277	0	1005277	intergenic_variant	TRUE	0.28	1e-13	13	NA	0.7366	[0.54-0.93] unit increase	Affymetrix, Illumina [~ 7400000] (imputed)	N	aging	http://purl.obolibrary.org/obo/GO_0007568	GCST005288	Genome-wide genotyping array	0.28	NA	0.7366
2018-02-13	29374233	Lu AT	2018-01-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29374233	GWAS of epigenetic aging rates in blood reveals a critical role for TERT.	Intrinsic epigenetic age acceleration	8,393 European ancestry individuals	1,023 African American individuals, 491 Hispanic individuals	3q25.33	3	160442133	TRIM59	TRIM59	NA	NA	ENSG00000213186	NA	NA	rs11706810-C	rs11706810	0	11706810	intron_variant	FALSE	0.45	2e-9	8.698970004336019	NA	0.4089	[0.28-0.54] unit increase	Affymetrix, Illumina [~ 7400000] (imputed)	N	aging	http://purl.obolibrary.org/obo/GO_0007568	GCST005287	Genome-wide genotyping array	0.45	NA	NA
2018-02-13	29374233	Lu AT	2018-01-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29374233	GWAS of epigenetic aging rates in blood reveals a critical role for TERT.	Intrinsic epigenetic age acceleration	8,393 European ancestry individuals	1,023 African American individuals, 491 Hispanic individuals	5p15.33	5	1287225	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs2736099-A	rs2736099	0	2736099	intron_variant	FALSE	0.36	1e-12	12	NA	0.631	[0.46-0.81] unit increase	Affymetrix, Illumina [~ 7400000] (imputed)	N	aging	http://purl.obolibrary.org/obo/GO_0007568	GCST005287	Genome-wide genotyping array	0.36	NA	NA
2018-02-13	29374233	Lu AT	2018-01-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29374233	GWAS of epigenetic aging rates in blood reveals a critical role for TERT.	Intrinsic epigenetic age acceleration	8,393 European ancestry individuals	1,023 African American individuals, 491 Hispanic individuals	6p22.3	6	18114015	KIF13A, NHLRC1	NA - NHLRC1	NA	ENSG00000187566	NA	NA	6425	rs143093668-T	rs143093668	0	143093668	intergenic_variant	TRUE	0.05	4e-25	24.397940008672037	NA	1.6799	[1.36-2] unit decrease	Affymetrix, Illumina [~ 7400000] (imputed)	N	aging	http://purl.obolibrary.org/obo/GO_0007568	GCST005287	Genome-wide genotyping array	0.05	NA	NA
2018-02-13	29374233	Lu AT	2018-01-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29374233	GWAS of epigenetic aging rates in blood reveals a critical role for TERT.	Intrinsic epigenetic age acceleration	8,393 European ancestry individuals	1,023 African American individuals, 491 Hispanic individuals	6p22.3	6	18110325	KIF13A, NHLRC1	NA - NHLRC1	NA	ENSG00000187566	NA	NA	10115	rs6915893-T	rs6915893	0	6915893	intergenic_variant	TRUE	0.39	2e-13	12.698970004336019	NA	0.5197	[0.38-0.66] unit increase	Affymetrix, Illumina [~ 7400000] (imputed)	N	aging	http://purl.obolibrary.org/obo/GO_0007568	GCST005287	Genome-wide genotyping array	0.39	NA	NA
2018-02-13	29374233	Lu AT	2018-01-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29374233	GWAS of epigenetic aging rates in blood reveals a critical role for TERT.	Intrinsic epigenetic age acceleration	8,393 European ancestry individuals	1,023 African American individuals, 491 Hispanic individuals	6p22.2	6	25624572	LRRC16A, SCGN	CARMIL1 - SCGN	ENSG00000079691	ENSG00000079689	NA	4042	27629	rs73397619-C	rs73397619	0	73397619	intergenic_variant	TRUE	0.29	2e-10	9.698970004336019	NA	0.4602	[0.32-0.6] unit decrease	Affymetrix, Illumina [~ 7400000] (imputed)	N	aging	http://purl.obolibrary.org/obo/GO_0007568	GCST005287	Genome-wide genotyping array	0.29	NA	NA
2018-02-13	29374233	Lu AT	2018-01-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29374233	GWAS of epigenetic aging rates in blood reveals a critical role for TERT.	Intrinsic epigenetic age acceleration	8,393 European ancestry individuals	1,023 African American individuals, 491 Hispanic individuals	17q22	17	55025006	STXBP4	STXBP4	NA	NA	ENSG00000166263	NA	NA	rs78781855-G	rs78781855	0	78781855	intron_variant	FALSE	0.22	6e-9	8.221848749616356	NA	0.475	[0.32-0.63] unit decrease	Affymetrix, Illumina [~ 7400000] (imputed)	N	aging	http://purl.obolibrary.org/obo/GO_0007568	GCST005287	Genome-wide genotyping array	0.22	NA	NA
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	16p11.2	16	31118574	NR	KAT8	NA	NA	ENSG00000103510	NA	NA	rs9925964-A	rs9925964	0	9925964	splice_region_variant	FALSE	0.619057790126741	7e-13	12.154901959985743	NA	0.019869572	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.619057790126741	NA	0.019869572
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	16q12.1	16	49028679	NR	NA - MTND4LP25	NA	ENSG00000260067	NA	NA	37888	rs2080454-A	rs2080454	0	2080454	intergenic_variant	TRUE	0.595292377611283	3e-12	11.522878745280337	NA	0.01925606	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.595292377611283	NA	0.01925606
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	16q12.2	16	53769662	NR	FTO	NA	NA	ENSG00000140718	NA	NA	rs1558902-A	rs1558902	0	1558902	intron_variant	FALSE	0.415284232669989	9e-199	198.04575749056067	NA	0.08215689	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.415284232669989	NA	0.08215689
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	17p13.2	17	5379957	NR	NUP88, RABEP1	NA	NA	ENSG00000108559, ENSG00000029725	NA	NA	rs1000940-A	rs1000940	0	1000940	intron_variant	FALSE	0.685265617581057	5e-9	8.301029995663981	NA	0.017490005	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.685265617581057	NA	0.017490005
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	17q25.3	17	80637924	NR	RPTOR	NA	NA	ENSG00000141564	NA	NA	rs12939549-A	rs12939549	0	12939549	intron_variant	FALSE	0.570476354917151	7e-11	10.154901959985743	NA	0.017547995	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.570476354917151	NA	0.017547995
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	18q11.2	18	23535096	NR	NPC1	NA	NA	ENSG00000141458	NA	NA	rs6507716-A	rs6507716	0	6507716	intron_variant	FALSE	0.521688595403712	4e-11	10.397940008672037	NA	0.019484619	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.521688595403712	NA	0.019484619
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	18q21.32	18	59216087	NR	SEC11C - GRP	ENSG00000166562	ENSG00000134443	NA	57255	4071	rs7243357-T	rs7243357	0	7243357	intergenic_variant	TRUE	0.815405245375581	5e-11	10.301029995663981	NA	0.02309739	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.815405245375581	NA	0.02309739
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	18q21.32	18	60161902	NR	RPS3AP49 - RNU4-17P	ENSG00000242060	ENSG00000202468	NA	11537	1665	rs6567160-T	rs6567160	0	6567160	intergenic_variant	TRUE	0.762873575358056	9e-66	65.04575749056067	NA	0.053833127	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.762873575358056	NA	0.053833127
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	19p13.11	19	18344015	NR	PGPEP1	NA	NA	ENSG00000130517	NA	NA	rs17724992-A	rs17724992	0	17724992	intron_variant	FALSE	0.743708279308239	5e-8	7.301029995663981	NA	0.017328002	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.743708279308239	NA	0.017328002
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	19p13.11	19	18709498	NR	CRTC1	NA	NA	ENSG00000105662	NA	NA	rs757318-A	rs757318	0	757318	intron_variant	FALSE	0.484583832022932	5e-13	12.301029995663981	NA	0.019826295	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.484583832022932	NA	0.019826295
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	19q13.11	19	33820576	NR	KCTD15 - NA	ENSG00000153885	NA	NA	4813	NA	rs29938-T	rs29938	0	29938	intergenic_variant	TRUE	0.340916157168463	4e-14	13.397940008672037	NA	0.02165926	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.340916157168463	NA	0.02165926
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	19q13.32	19	44892362	NR	TOMM40	NA	NA	ENSG00000130204	NA	NA	rs2075650-A	rs2075650	0	2075650	intron_variant	FALSE	0.847998234602839	4e-10	9.397940008672037	NA	0.025690204	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.847998234602839	NA	0.025690204
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	19q13.32	19	45676926	NR	GIPR	NA	NA	ENSG00000010310	NA	NA	rs11672660-T	rs11672660	0	11672660	intron_variant	FALSE	0.218363659676388	3e-16	15.522878745280337	NA	0.028914098	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.218363659676388	NA	0.028914098
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	19q13.32	19	47065746	NR	ZC3H4	NA	NA	ENSG00000130749	NA	NA	rs3810291-A	rs3810291	0	3810291	3_prime_UTR_variant	FALSE	0.664069524669446	1e-19	19	NA	0.02794018	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.664069524669446	NA	0.02794018
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	20q13.2	20	52471323	NR	LINC01524	NA	NA	ENSG00000234948	NA	NA	rs6091540-T	rs6091540	0	6091540	intron_variant	FALSE	0.277840319422908	1e-9	9	NA	0.018517034	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.277840319422908	NA	0.018517034
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index (age>50)	up to 90,988 European ancestry men, up to 106,622 European ancestry women	NA	16q12.2	16	53785257	FTO, CHD9, LOC643802, BL2, AKTIP, RPGRIP1, IRX3	FTO	NA	NA	ENSG00000140718	NA	NA	rs9936385-C	rs9936385	0	9936385	intron_variant	FALSE	0.39	1e-97	97	NA	0.073	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005952	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.39	NA	0.073
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index (age>50)	up to 90,988 European ancestry men, up to 106,622 European ancestry women	NA	2p25.3	2	622827	TMEM18, ACP1, FAM150B, SH3YL1, SNTG2, LOC339822	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	76160	41050	rs2867125-C	rs2867125	0	2867125	intergenic_variant	TRUE	0.83	2e-30	29.69897000433602	NA	0.051	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005952	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.83	NA	0.051
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index (age>50)	up to 90,988 European ancestry men, up to 106,622 European ancestry women	NA	18q21.32	18	60205756	MC4R, PMAIP1	RNU4-17P - NA	ENSG00000202468	NA	NA	42049	NA	rs12955983-G	rs12955983	0	12955983	intergenic_variant	TRUE	0.28	2e-23	22.69897000433602	NA	0.038	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005952	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.28	NA	0.038
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index (age>50)	up to 90,988 European ancestry men, up to 106,622 European ancestry women	NA	2p23.3	2	24915171	ADCY3, NCOA1, PTRHD1, CENPO, DNAJC27, DNAJC27-AS1, EFR3B, POMC, DNMT3A, MIR1301, DTNB	ADCY3	NA	NA	ENSG00000138031	NA	NA	rs6737082-C	rs6737082	0	6737082	intron_variant	FALSE	0.47	5e-9	8.301029995663981	NA	0.022	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005952	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.47	NA	0.022
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index (age>50)	up to 90,988 European ancestry men, up to 106,622 European ancestry women	NA	10q25.2	10	112992744	TCF7L2, MIR4295, VTI1A	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs17747324-T	rs17747324	0	17747324	intron_variant	FALSE	0.77	3e-13	12.522878745280337	NA	0.031	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005952	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.77	NA	0.031
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index (age>50)	up to 90,988 European ancestry men, up to 106,622 European ancestry women	NA	6q25.3	6	160370338	SLC22A3, MAS1, AIRN, IGF2R, SLC22A1, SLC22A2, LPAL2, LPA, PLG, LOC729603	SLC22A3	NA	NA	ENSG00000146477	NA	NA	rs3127574-C	rs3127574	0	3127574	non_coding_transcript_exon_variant	FALSE	0.51	2e-8	7.698970004336019	NA	0.019	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005952	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.51	NA	0.019
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index (age>50)	up to 90,988 European ancestry men, up to 106,622 European ancestry women	NA	2q24.3	2	164735880	COBLL1, GRB14, SNORA70F, SLC38A11, SCN3A	COBLL1	NA	NA	ENSG00000082438	NA	NA	rs3769885-A	rs3769885	0	3769885	intron_variant	FALSE	0.48	4e-9	8.397940008672037	NA	0.02	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005952	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.48	NA	0.02
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index (age>50)	up to 90,988 European ancestry men, up to 106,622 European ancestry women	NA	19q13.32	19	44919689	APOC1, ZNF229, IGSF23, BCL3, PVRL2, CLPTM1, GEMIN7, EXOC3L2, KLC3, ZNF180, PVR, CBLC, TOMM40, RELB, PPP1R37, MARK4, ERCC1, CEACAM20, MIR4531, BCAM, APOE, CLASRP, BLOC1S3, CKM, CEACAM22P	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855	NA	340	7115	rs4420638-A	rs4420638	0	4420638	regulatory_region_variant	TRUE	0.82	9e-12	11.045757490560675	NA	0.04	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005952	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.82	NA	0.04
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index (age <50)	up to 51,625 European ancestry men, up to 60,654 European ancestry women	NA	2p23.3	2	24915171	ADCY3, NCOA1, PTRHD1, CENPO, DNAJC27, DNAJC27-AS1, EFR3B, POMC, DNMT3A, MIR1301, DTNB	ADCY3	NA	NA	ENSG00000138031	NA	NA	rs6737082-C	rs6737082	0	6737082	intron_variant	FALSE	0.47	6e-20	19.221848749616356	NA	0.046	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005953	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.47	NA	0.046
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index (age <50)	up to 51,625 European ancestry men, up to 60,654 European ancestry women	NA	1p31.1	1	74527379	TNNI3K, C1orf173, CRYZ, LRRIQ3, TYW3, FPGT, FPGT-TNNI3K	TNNI3K, FPGT-TNNI3K	NA	NA	ENSG00000116783, ENSG00000259030	NA	NA	rs1514174-C	rs1514174	0	1514174	intron_variant	FALSE	0.43	3e-15	14.522878745280337	NA	0.039	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005953	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.43	NA	0.039
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	11p15.4	11	8647890	NR	TRIM66	NA	NA	ENSG00000166436	NA	NA	rs10840100-A	rs10840100	0	10840100	intron_variant	FALSE	0.352929630935745	2e-15	14.698970004336019	NA	0.022190128	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.352929630935745	NA	0.022190128
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	11p14.1	11	27680836	NR	BDNF, BDNF-AS	NA	NA	ENSG00000176697, ENSG00000245573	NA	NA	rs16917237-T	rs16917237	0	16917237	intron_variant	FALSE	0.207486122815417	1e-34	34	NA	0.040926106	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.207486122815417	NA	0.040926106
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	11p11.2	11	43620580	NR	MIR129-2 - HSD17B12	ENSG00000199077	ENSG00000149084	NA	39097	60100	rs4755726-T	rs4755726	0	4755726	intron_variant	TRUE	0.30427542745583	7e-9	8.154901959985743	NA	0.01696129	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.30427542745583	NA	0.01696129
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	11p11.2	11	43842728	NR	HSD17B12	NA	NA	ENSG00000149084	NA	NA	rs2176598-T	rs2176598	0	2176598	intron_variant	FALSE	0.252385805925411	1e-8	8	NA	0.017458763	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.252385805925411	NA	0.017458763
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	11p11.2	11	47508395	NR	CELF1	NA	NA	ENSG00000149187	NA	NA	rs7124681-A	rs7124681	0	7124681	intron_variant	FALSE	0.409389443762275	3e-19	18.522878745280337	NA	0.024504084	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.409389443762275	NA	0.024504084
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	11p11.2	11	47629441	NR	MTCH2	NA	NA	ENSG00000109919	NA	NA	rs3817334-T	rs3817334	0	3817334	intron_variant	FALSE	0.407932176463293	1e-18	18	NA	0.024106821	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.407932176463293	NA	0.024106821
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	11q23.3	11	115151684	NR	NA - CADM1	NA	ENSG00000182985	NA	NA	17534	rs12286929-A	rs12286929	0	12286929	intergenic_variant	TRUE	0.477081173735161	1e-11	11	NA	0.018081361	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.477081173735161	NA	0.018081361
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	12q13.12	12	49853685	NR	BCDIN3D - RPL35AP28	ENSG00000186666	ENSG00000242041	NA	10579	9488	rs7138803-A	rs7138803	0	7138803	intergenic_variant	TRUE	0.386681641023647	2e-31	30.69897000433602	NA	0.0327098	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.386681641023647	NA	0.0327098
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	12q24.31	12	122339230	NR	CLIP1	NA	NA	ENSG00000130779	NA	NA	rs10846664-A	rs10846664	0	10846664	intron_variant	FALSE	0.246612754192508	3e-8	7.522878745280337	NA	0.017600372	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.246612754192508	NA	0.017600372
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	13q12.2	13	27443645	NR	MTIF3	NA	NA	ENSG00000122033	NA	NA	rs12016871-T	rs12016871	1	9581854	intron_variant	FALSE	0.202241662528225	1e-13	13	NA	0.027732678	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.202241662528225	NA	0.027732678
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	13q14.3	13	53528071	NR	NA	NA	NA	NA	NA	NA	rs12429545-A	rs12429545	0	12429545	intron_variant	TRUE	0.133208977081223	7e-17	16.154901959985743	NA	0.033930767	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.133208977081223	NA	0.033930767
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	13q21.32	13	65631572	NR	NA	NA	NA	NA	NA	NA	rs9540493-A	rs9540493	0	9540493	intergenic_variant	TRUE	0.451974617419625	2e-9	8.698970004336019	NA	0.017341554	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.451974617419625	NA	0.017341554
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	14q12	14	25458973	NR	NA	NA	NA	NA	NA	NA	rs10132280-A	rs10132280	0	10132280	intergenic_variant	TRUE	0.319714929358119	5e-13	12.301029995663981	NA	0.021317558	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.319714929358119	NA	0.021317558
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	14q12	14	29267632	NR	NA	NA	NA	NA	NA	NA	rs12885454-A	rs12885454	0	12885454	non_coding_transcript_exon_variant	TRUE	0.359525724658445	5e-14	13.301029995663981	NA	0.021277636	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.359525724658445	NA	0.021277636
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	14q12	14	30045906	NR	PRKD1	NA	NA	ENSG00000184304	NA	NA	rs11847697-T	rs11847697	0	11847697	intron_variant	FALSE	0.0419583872651932	2e-10	9.698970004336019	NA	0.046948265	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.0419583872651932	NA	0.046948265
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	14q31.1	14	79433111	NR	NRXN3	NA	NA	ENSG00000021645	NA	NA	rs7141420-T	rs7141420	0	7141420	intron_variant	FALSE	0.523140564168958	1e-24	24	NA	0.027489452	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.523140564168958	NA	0.027489452
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	15q21.2	15	51456413	NR	DMXL2	NA	NA	ENSG00000104093	NA	NA	rs3736485-A	rs3736485	0	3736485	non_coding_transcript_exon_variant	FALSE	0.452684512992502	2e-10	9.698970004336019	NA	0.017159417	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.452684512992502	NA	0.017159417
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	15q23	15	67794500	NR	MAP2K5	NA	NA	ENSG00000137764	NA	NA	rs2241423-A	rs2241423	0	2241423	intron_variant	FALSE	0.215263645020958	5e-23	22.30102999566398	NA	0.03273353	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.215263645020958	NA	0.03273353
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	15q24.1	15	72796528	NR	ADPGK-AS1	NA	NA	ENSG00000260898	NA	NA	rs8027181-A	rs8027181	0	8027181	intron_variant	FALSE	0.310703425786865	2e-9	8.698970004336019	NA	0.019309552	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.310703425786865	NA	0.019309552
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	16p13.3	16	3577357	NR	NLRC3	NA	NA	ENSG00000167984	NA	NA	rs758747-T	rs758747	0	758747	5_prime_UTR_variant	FALSE	0.2658971403345	2e-7	6.698970004336019	NA	0.01722961	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.2658971403345	NA	0.01722961
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	16p13.3	16	3963466	NR	ADCY9	NA	NA	ENSG00000162104	NA	NA	rs2531995-T	rs2531995	0	2531995	3_prime_UTR_variant	FALSE	0.615629723953184	9e-15	14.045757490560675	NA	0.024907207	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.615629723953184	NA	0.024907207
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	16p12.3	16	19924067	NR	GPRC5B - NA	ENSG00000167191	NA	NA	37900	NA	rs12446632-A	rs12446632	0	12446632	intergenic_variant	TRUE	0.133780488233125	1e-26	26	NA	0.04259146	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.133780488233125	NA	0.04259146
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	16p12.1	16	28322090	NR	SBK1	NA	NA	ENSG00000188322	NA	NA	rs2650492-A	rs2650492	0	2650492	3_prime_UTR_variant	FALSE	0.306781245179052	7e-15	14.154901959985743	NA	0.024314765	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.306781245179052	NA	0.024314765
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	16p11.2	16	28878165	NR	SH2B1 - ATP2A1	ENSG00000178188	ENSG00000196296	NA	3953	240	rs3888190-A	rs3888190	0	3888190	intron_variant	TRUE	0.403407646421344	1e-29	29	NA	0.030506346	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.403407646421344	NA	0.030506346
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	16p11.2	16	29956694	NR	TMEM219	NA	NA	ENSG00000149932	NA	NA	rs7204797-T	rs7204797	0	7204797	intron_variant	FALSE	0.440736937631702	9e-10	9.045757490560675	NA	0.018262625	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.440736937631702	NA	0.018262625
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	6p21.31	6	34595387	NR	ILRUN	NA	NA	ENSG00000196821	NA	NA	rs205262-A	rs205262	0	205262	intron_variant	FALSE	0.727194053237101	2e-14	13.698970004336019	NA	0.023253435	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.727194053237101	NA	0.023253435
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	6p21.31	6	34860776	NR	UHRF1BP1	NA	NA	ENSG00000065060	NA	NA	rs6457796-T	rs6457796	0	6457796	intron_variant	FALSE	0.72717305237299	1e-14	14	NA	0.023165043	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.72717305237299	NA	0.023165043
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	6p21.2	6	40380914	NR	TDRG1	NA	NA	ENSG00000204091	NA	NA	rs2033529-A	rs2033529	0	2033529	intron_variant	FALSE	0.710000744534429	4e-10	9.397940008672037	NA	0.018617788	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.710000744534429	NA	0.018617788
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	6p12.3	6	50830813	NR	TFAP2B	NA	NA	ENSG00000008196	NA	NA	rs2206277-T	rs2206277	0	2206277	intron_variant	FALSE	0.185933787947696	7e-32	31.154901959985743	NA	0.041263442	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.185933787947696	NA	0.041263442
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	6q21	6	108656460	NR	FOXO3	NA	NA	ENSG00000118689	NA	NA	rs9400239-T	rs9400239	0	9400239	5_prime_UTR_variant	FALSE	0.307456911187995	5e-9	8.301029995663981	NA	0.017088454	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.307456911187995	NA	0.017088454
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	6q22.31	6	119864519	NR	NA	NA	NA	NA	NA	NA	rs9374842-T	rs9374842	0	9374842	intergenic_variant	TRUE	0.74468928820411	8e-8	7.096910013008056	NA	0.016438592	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.74468928820411	NA	0.016438592
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	6q22.31	6	119988849	NR	NA - MIR3144	NA	ENSG00000265725	NA	NA	26330	rs7775754-C	rs7775754	0	7775754	intergenic_variant	TRUE	0.617456537732821	5e-10	9.301029995663981	NA	0.019277759	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.617456537732821	NA	0.019277759
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	6q26	6	162612318	NR	PRKN	NA	NA	ENSG00000185345	NA	NA	rs13191362-A	rs13191362	0	13191362	intron_variant	FALSE	0.877272817859194	7e-11	10.154901959985743	NA	0.027373856	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.877272817859194	NA	0.027373856
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	7q11.23	7	75533848	NR	HIP1	NA	NA	ENSG00000127946	NA	NA	rs1167827-A	rs1167827	0	1167827	3_prime_UTR_variant	FALSE	0.441576929328427	1e-12	12	NA	0.020421537	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.441576929328427	NA	0.020421537
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	7q11.23	7	77005146	NR	DTX2P1-UPK3BP1-PMS2P11, UPK3BP1	NA	NA	ENSG00000265479, ENSG00000242435	NA	NA	rs17149254-T	rs17149254	0	17149254	intron_variant	FALSE	0.185417040776293	3e-11	10.522878745280337	NA	0.037487555	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.185417040776293	NA	0.037487555
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	7q21.3	7	93568420	NR	CALCR	NA	NA	ENSG00000004948	NA	NA	rs9641123-C	rs9641123	0	9641123	intron_variant	FALSE	0.428300976029584	2e-8	7.698970004336019	NA	0.017202783	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.428300976029584	NA	0.017202783
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	7q21.3	7	95540202	NR	ASB4	NA	NA	ENSG00000005981	NA	NA	rs6465468-T	rs6465468	0	6465468	3_prime_UTR_variant	FALSE	0.307836480675703	3e-8	7.522878745280337	NA	0.017052807	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.307836480675703	NA	0.017052807
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	8q21.13	8	75894349	NR	NA	NA	NA	NA	NA	NA	rs17405819-T	rs17405819	0	17405819	intergenic_variant	TRUE	0.698598932727065	6e-16	15.221848749616356	NA	0.023545315	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.698598932727065	NA	0.023545315
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	8q21.13	8	80463222	NR	RNU6-1213P - Y_RNA	ENSG00000252884	ENSG00000199964	NA	57613	21367	rs16907751-T	rs16907751	0	16907751	intron_variant	TRUE	0.0722737779001418	3e-9	8.522878745280337	NA	0.037375808	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.0722737779001418	NA	0.037375808
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	8q21.2	8	84165451	NR	TPM3P3 - RALYL	ENSG00000254195	ENSG00000184672	NA	2980	17336	rs733594-T	rs733594	0	733594	intergenic_variant	TRUE	0.731202868724191	2e-8	7.698970004336019	NA	0.01730739	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.731202868724191	NA	0.01730739
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	9p22.3	9	15634328	NR	CCDC171	NA	NA	ENSG00000164989	NA	NA	rs4740619-T	rs4740619	0	4740619	intron_variant	FALSE	0.545371365417758	2e-10	9.698970004336019	NA	0.017116887	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.545371365417758	NA	0.017116887
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	9p21.1	9	28415514	NR	LINGO2	NA	NA	ENSG00000174482	NA	NA	rs10968577-T	rs10968577	0	10968577	intron_variant	FALSE	0.317299425644751	1e-16	16	NA	0.02500833	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.317299425644751	NA	0.02500833
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	9q31.3	9	109170062	NR	FRRS1L - EPB41L4B	ENSG00000260230	ENSG00000095203	NA	2813	1912	rs6477694-T	rs6477694	0	6477694	intergenic_variant	TRUE	0.632272921963274	5e-12	11.301029995663981	NA	0.019407246	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.632272921963274	NA	0.019407246
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	9q33.1	9	117616205	NR	NA - RPL35AP22	NA	ENSG00000235133	NA	NA	69049	rs1928295-T	rs1928295	0	1928295	intergenic_variant	TRUE	0.54701226419507	2e-12	11.698970004336019	NA	0.019130511	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.54701226419507	NA	0.019130511
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	9q33.3	9	126698635	NR	LMX1B	NA	NA	ENSG00000136944	NA	NA	rs10733682-A	rs10733682	0	10733682	3_prime_UTR_variant	FALSE	0.476859395790286	3e-11	10.522878745280337	NA	0.018371465	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.476859395790286	NA	0.018371465
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	10q23.1	10	85651147	NR	GRID1	NA	NA	ENSG00000182771	NA	NA	rs7899106-A	rs7899106	0	7899106	intron_variant	FALSE	0.946180015931271	3e-13	12.522878745280337	NA	0.04524876	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.946180015931271	NA	0.04524876
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	10q24.31	10	100635683	NR	HIF1AN - Metazoa_SRP	ENSG00000166135	ENSG00000278007	NA	75685	31012	rs17094222-T	rs17094222	0	17094222	intergenic_variant	TRUE	0.791660103324089	1e-9	9	NA	0.020542767	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.791660103324089	NA	0.020542767
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	10q24.32	10	103013607	NR	CNNM2	NA	NA	ENSG00000148842	NA	NA	rs11191514-T	rs11191514	0	11191514	intron_variant	FALSE	0.0904364237060407	3e-11	10.522878745280337	NA	0.031324036	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.0904364237060407	NA	0.031324036
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	10q24.33	10	103146454	NR	NT5C2	NA	NA	ENSG00000076685	NA	NA	rs11191580-T	rs11191580	0	11191580	intron_variant	FALSE	0.909791403908989	2e-11	10.698970004336019	NA	0.031222157	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.909791403908989	NA	0.031222157
2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals	NA	10q25.2	10	112998590	NR	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs7903146-T	rs7903146	0	7903146	intron_variant	FALSE	0.28797015591893	3e-13	12.522878745280337	NA	0.021989034	unit decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST005951	Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip]	0.28797015591893	NA	0.021989034
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	5q33.3	5	158418394	EBF1	LINC02227 - NA	ENSG00000276778	NA	NA	8621	NA	rs11953630-?	rs11953630	0	11953630	intergenic_variant	TRUE	NA	7e-23	22.154901959985743	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	6p22.2	6	26090951	HFE	HFE	NA	NA	ENSG00000010704	NA	NA	rs1799945-?	rs1799945	0	1799945	missense_variant	FALSE	NA	4e-33	32.39794000867204	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	6p21.1	6	43302413	SLC22A7	CRIP3, SLC22A7	NA	NA	ENSG00000146215, ENSG00000137204	NA	NA	rs2270860-?	rs2270860	0	2270860	splice_region_variant	FALSE	NA	4e-11	10.397940008672037	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	6p21.1	6	43312975	CRIP3	ZNF318	NA	NA	ENSG00000171467	NA	NA	rs10948071-?	rs10948071	0	10948071	intron_variant	FALSE	NA	1e-10	10	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	6q22.32	6	126794309	RSPO3	NA	NA	NA	NA	NA	NA	rs13209747-?	rs13209747	0	13209747	intron_variant	TRUE	NA	6e-39	38.221848749616356	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	6q25.1	6	150683634	PLEKHG1	PLEKHG1	NA	NA	ENSG00000120278	NA	NA	rs17080102-?	rs17080102	0	17080102	5_prime_UTR_variant	FALSE	NA	1e-28	28	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	7q36.1	7	150993088	NOS3	NOS3	NA	NA	ENSG00000164867	NA	NA	rs3918226-?	rs3918226	0	3918226	intron_variant	FALSE	NA	4e-33	32.39794000867204	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	8p23.1	8	11576400	BLK, GATA4	LINC00208	NA	NA	ENSG00000170983	NA	NA	rs2898290-?	rs2898290	0	2898290	non_coding_transcript_exon_variant	FALSE	NA	6e-13	12.221848749616356	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	8p23.1	8	11594668	BLK, GATA4	LINC00208 - GATA4	ENSG00000170983	ENSG00000285109	NA	11851	82291	rs4841569-?	rs4841569	0	4841569	regulatory_region_variant	TRUE	NA	2e-10	9.698970004336019	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	10p12.31	10	18418519	CACNB2	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs1813353-?	rs1813353	0	1813353	intron_variant	FALSE	NA	2e-21	20.69897000433602	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	10q21.2	10	61707795	C10orf107	CABCOCO1	NA	NA	ENSG00000183346	NA	NA	rs4590817-?	rs4590817	0	4590817	intron_variant	FALSE	NA	5e-25	24.30102999566398	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	10q21.2	10	61764833	c10orf107	CABCOCO1	NA	NA	ENSG00000183346	NA	NA	rs1530440-?	rs1530440	0	1530440	intron_variant	FALSE	NA	2e-16	15.698970004336019	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	10q24.32	10	103086421	CYP17A1, NT5C2, CNNM2-AS3MT	CNNM2	NA	NA	ENSG00000148842	NA	NA	rs11191548-?	rs11191548	0	11191548	3_prime_UTR_variant	FALSE	NA	1e-17	17	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	10q25.3	10	114021768	ADRB1	NHLRC2 - ADRB1	ENSG00000196865	ENSG00000043591	NA	104574	22098	rs2782980-?	rs2782980	0	2782980	regulatory_region_variant	TRUE	NA	1e-21	21	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	10q25.3	10	114045297	ADRB1	ADRB1	NA	NA	ENSG00000043591	NA	NA	rs1801253-?	rs1801253	0	1801253	missense_variant	FALSE	NA	3e-22	21.522878745280337	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	11p15.5	11	1884062	LSP1, TNNT3	LSP1	NA	NA	ENSG00000130592	NA	NA	rs661348-?	rs661348	0	661348	intron_variant	FALSE	NA	3e-23	22.522878745280337	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	11p15.5	11	1995678	H19	H19	NA	NA	ENSG00000130600	NA	NA	rs217727-?	rs217727	0	217727	non_coding_transcript_exon_variant	FALSE	NA	1e-8	8	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	11p15.3	11	13272358	ARNTL	NA - ARNTL	NA	ENSG00000133794	NA	NA	4294	rs900145-?	rs900145	0	900145	intergenic_variant	TRUE	NA	7e-18	17.154901959985743	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	11p15.2	11	16343736	SOX6	SOX6	NA	NA	ENSG00000110693	NA	NA	rs2014408-?	rs2014408	0	2014408	intron_variant	FALSE	NA	5e-23	22.30102999566398	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	11q12.2	11	61510774	LRRC10B	LRRC10B	NA	NA	ENSG00000204950	NA	NA	rs751984-?	rs751984	0	751984	3_prime_UTR_variant	FALSE	NA	2e-24	23.69897000433602	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	11q13.1	11	65641466	SIPA1, RELA	SIPA1	NA	NA	ENSG00000213445	NA	NA	rs3741378-?	rs3741378	0	3741378	missense_variant	FALSE	NA	1e-9	9	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	11q22.1	11	100722807	FLJ32810, TMEM133	ARHGAP42	NA	NA	ENSG00000165895	NA	NA	rs633185-?	rs633185	0	633185	intron_variant	FALSE	NA	1e-40	40	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	12p12.2	12	20040038	PDE3A	LINC02398	NA	NA	ENSG00000256287	NA	NA	rs3752728-?	rs3752728	0	3752728	intron_variant	FALSE	NA	1e-35	35	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	12q21.33	12	89666809	ATP2B1	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs17249754-?	rs17249754	0	17249754	intron_variant	FALSE	NA	6e-57	56.221848749616356	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2018-09-05	29455858	Sung YJ	2018-02-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Diastolic blood pressure (cigarette smoking interaction)	80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals	305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals	12q24.12	12	111446804	SH2B3, ATXN2	SH2B3, ATXN2	NA	NA	ENSG00000111252, ENSG00000204842	NA	NA	rs3184504-?	rs3184504	0	3184504	missense_variant	FALSE	NA	6e-67	66.22184874961636	NA	NA	NA	Affymetrix, Illumina [18800000] (imputed)	N	smoking status measurement, diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336	GCST006187	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	10q21.1	10	52777079	NR	MBL2 - Y_RNA	ENSG00000165471	ENSG00000199964	NA	4295	75528	rs7899547-?	rs7899547	0	7899547	regulatory_region_variant	TRUE	NR	2e-102	101.69897000433602	(EA, Mannose-binding protein C)	NA	NA	Affymetrix [509946]	N	mannose-binding protein C measurement	http://www.ebi.ac.uk/efo/EFO_0008224	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	2p25.3	2	254215	NR	SH3YL1	NA	NA	ENSG00000035115	NA	NA	rs17713879-?	rs17713879	0	17713879	intron_variant	FALSE	NR	2e-215	214.69897000433602	(EA, Low molecular weight phosphotyrosine protein phosphatase)	NA	NA	Affymetrix [509946]	N	low molecular weight phosphotyrosine protein phosphatase measurement	http://www.ebi.ac.uk/efo/EFO_0008213	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	13q34	13	113121904	NR	F7 - F10	ENSG00000057593	ENSG00000126218	NA	1219	895	rs474671-?	rs474671	0	474671	intergenic_variant	TRUE	NR	6e-65	64.22184874961636	(EA, Coagulation Factor VII)	NA	NA	Affymetrix [509946]	N	factor VII measurement	http://www.ebi.ac.uk/efo/EFO_0004619	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q31.3	1	196705852	NR	CFH	NA	NA	ENSG00000000971	NA	NA	rs1048663-?	rs1048663	0	1048663	intron_variant	FALSE	NR	5e-25	24.30102999566398	(EA, Complement factor H)	NA	NA	Affymetrix [509946]	N	complement factor H measurement	http://www.ebi.ac.uk/efo/EFO_0008097	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q32.1	1	203205542	NR	CHI3L1 - CHIT1	ENSG00000133048	ENSG00000133063	NA	18838	7285	rs2486950-?	rs2486950	0	2486950	intergenic_variant	TRUE	NR	8e-111	110.09691001300806	(EA, Chitotriosidase-1)	NA	NA	Affymetrix [509946]	N	chitotriosidase-1 measurement	http://www.ebi.ac.uk/efo/EFO_0008084	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	7q34	7	143391730	NR	EPHA1, EPHA1	NA	NA	ENSG00000146904, ENSG00000284816	NA	NA	rs1804527-?	rs1804527	0	1804527	synonymous_variant	FALSE	NR	5e-67	66.30102999566398	(EA, Ephrin type-A receptor 1)	NA	NA	Affymetrix [509946]	N	ephrin type-A receptor 1 measurement	http://www.ebi.ac.uk/efo/EFO_0008123	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	9q34.2	9	133440409	NR	ADAMTS13	NA	NA	ENSG00000160323	NA	NA	rs28647808-?	rs28647808	0	28647808	missense_variant	FALSE	NR	3e-42	41.52287874528034	(EA, A disintegrin and metalloproteinase with thrombospondin motifs 13)	NA	NA	Affymetrix [509946]	N	a disintegrin and metalloproteinase with thrombospondin motifs 13	http://www.ebi.ac.uk/efo/EFO_0008011	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q27.3	3	186616215	NR	AHSG	NA	NA	ENSG00000145192	NA	NA	rs2070632-?	rs2070632	0	2070632	intron_variant	FALSE	NR	2e-34	33.69897000433602	(EA, Alpha-2-HS-glycoprotein)	NA	NA	Affymetrix [509946]	N	alpha-2-HS-glycoprotein measurement	http://www.ebi.ac.uk/efo/EFO_0008020	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	22q11.1	22	17105693	NR	IL17RA	NA	NA	ENSG00000177663	NA	NA	rs2241047-?	rs2241047	0	2241047	intron_variant	FALSE	NR	4e-96	95.39794000867204	(EA, Interleukin-17 receptor A)	NA	NA	Affymetrix [509946]	N	interleukin 17 receptor A measurement	http://www.ebi.ac.uk/efo/EFO_0008175	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	2q12.1	2	102309902	NR	FAM183DP - IL1RL1	ENSG00000205716	ENSG00000115602	NA	59647	1600	rs12470864-?	rs12470864	0	12470864	intergenic_variant	TRUE	NR	3e-69	68.52287874528034	(EA, Interleukin-1 receptor-like 1)	NA	NA	Affymetrix [509946]	N	interleukin 1 receptor-like 1 measurement	http://www.ebi.ac.uk/efo/EFO_0008168	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	2p11.2	2	85708159	NR	GNLY - RNU1-38P	ENSG00000115523	ENSG00000199687	NA	9307	20035	rs7577293-?	rs7577293	0	7577293	regulatory_region_variant	TRUE	NR	5e-76	75.30102999566398	(EA, Granulysin)	NA	NA	Affymetrix [509946]	N	granulysin measurement	http://www.ebi.ac.uk/efo/EFO_0008144	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	2q12.1	2	102267158	NR	FAM183DP - IL1RL1	ENSG00000205716	ENSG00000115602	NA	16903	44344	rs1882510-?	rs1882510	0	1882510	regulatory_region_variant	TRUE	NR	1e-26	26	(EA, Interleukin-18 receptor 1)	NA	NA	Affymetrix [509946]	N	interleukin 18 receptor 1 measurement	http://www.ebi.ac.uk/efo/EFO_0008178	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3q27.3	3	186733074	NR	KNG1	NA	NA	ENSG00000113889	NA	NA	rs5030049-?	rs5030049	0	5030049	intron_variant	FALSE	NR	1e-96	96	(EA, Kininogen-1)	NA	NA	Affymetrix [509946]	N	kininogen-1 measurement	http://www.ebi.ac.uk/efo/EFO_0008198	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q24.2	1	168552179	NR	XCL2 - XCL1	ENSG00000143185	ENSG00000143184	NA	8182	24426	rs1933112-?	rs1933112	0	1933112	intergenic_variant	TRUE	NR	6e-7	6.221848749616356	(EA, Lymphotactin)	NA	NA	Affymetrix [509946]	N	lymphotactin measurement	http://www.ebi.ac.uk/efo/EFO_0008214	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1p36.13	1	19979653	NR	PLA2G2A	NA	NA	ENSG00000188257	NA	NA	rs11573156-?	rs11573156	0	11573156	5_prime_UTR_variant	FALSE	NR	1e-38	38	(EA, Phospholipase A2, membrane associated)	NA	NA	Affymetrix [509946]	N	phospholipase A2, membrane associated measurement	http://www.ebi.ac.uk/efo/EFO_0008259	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	17q12	17	36000884	NR	CCL15, CCL15, CCL15-CCL14, CCL15-CCL14	NA	NA	ENSG00000275528, ENSG00000275718, ENSG00000275688, ENSG00000282521	NA	NA	rs854624-?	rs854624	0	854624	intron_variant	FALSE	NR	2e-119	118.69897000433602	(EA, C-C motif chemokine 15)	NA	NA	Affymetrix [509946]	N	C-C motif chemokine 15 measurement	http://www.ebi.ac.uk/efo/EFO_0008043	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	1q21.3	1	150968149	NR	CERS2	NA	NA	ENSG00000143418	NA	NA	rs267738-?	rs267738	0	267738	missense_variant	FALSE	NR	9e-17	16.045757490560675	(EA, Cathepsin S)	NA	NA	Affymetrix [509946]	N	cathepsin S measurement	http://www.ebi.ac.uk/efo/EFO_0008073	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	22q12.3	22	32771883	NR	SYN3	NA	NA	ENSG00000185666	NA	NA	rs2413151-?	rs2413151	0	2413151	intron_variant	FALSE	NR	6e-100	99.22184874961636	(EA, Metalloproteinase inhibitor 3)	NA	NA	Affymetrix [509946]	N	metalloproteinase inhibitor 3 measurement	http://www.ebi.ac.uk/efo/EFO_0008231	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	7q11.23	7	76226193	NR	SRRM3	NA	NA	ENSG00000177679	NA	NA	rs11770797-?	rs11770797	0	11770797	intron_variant	FALSE	NR	2e-6	5.698970004336019	(EA, NADPH--cytochrome P450 reductase)	NA	NA	Affymetrix [509946]	N	NADPH--cytochrome P450 reductase measurement	http://www.ebi.ac.uk/efo/EFO_0008242	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	13q14.13	13	46028027	NR	ZC3H13	NA	NA	ENSG00000123200	NA	NA	rs2094247-?	rs2094247	0	2094247	intron_variant	FALSE	NR	6e-73	72.22184874961636	(EA, Carboxypeptidase B2)	NA	NA	Affymetrix [509946]	N	carboxypeptidase B2 measurement	http://www.ebi.ac.uk/efo/EFO_0008069	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4q13.3	4	73998280	NR	CXCL5	NA	NA	ENSG00000163735	NA	NA	rs425535-?	rs425535	0	425535	missense_variant	FALSE	NR	1e-9	9	(EA, C-X-C motif chemokine 5)	NA	NA	Affymetrix [509946]	N	C-X-C motif chemokine 5 measurement	http://www.ebi.ac.uk/efo/EFO_0008058	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	4q13.3	4	73991991	NR	PPBP - CXCL5	ENSG00000163736	ENSG00000163735	NA	3801	3651	rs2472649-?	rs2472649	0	2472649	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(EA, C-X-C motif chemokine 5)	NA	NA	Affymetrix [509946]	N	C-X-C motif chemokine 5 measurement	http://www.ebi.ac.uk/efo/EFO_0008058	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	3p21.1	3	53842191	NR	CHDH	NA	NA	ENSG00000016391	NA	NA	rs6801605-?	rs6801605	0	6801605	intron_variant	FALSE	NR	7e-19	18.154901959985743	(EA, interleukin-17 receptor B)	NA	NA	Affymetrix [509946]	N	interleukin 17 receptor B measurement	http://www.ebi.ac.uk/efo/EFO_0008176	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19q13.2	19	40757498	NR	SNRPA	NA	NA	ENSG00000077312	NA	NA	rs2230694-?	rs2230694	0	2230694	missense_variant	FALSE	NR	1e-68	68	(EA, Melanoma-derived growth regulatory protein)	NA	NA	Affymetrix [509946]	N	melanoma-derived growth regulatory protein measurement	http://www.ebi.ac.uk/efo/EFO_0008229	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-07-18	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Blood protein levels	997 European ancestry individuals	338 Arab, South Asian and Filipino ancestry individuals	19q13.2	19	40777460	NR	MIA-RAB4B, MIA	NA	NA	ENSG00000268975, ENSG00000261857	NA	NA	rs2233159-?	rs2233159	0	2233159	3_prime_UTR_variant	FALSE	NR	1e-69	69	(EA, Melanoma-derived growth regulatory protein)	NA	NA	Affymetrix [509946]	N	melanoma-derived growth regulatory protein measurement	http://www.ebi.ac.uk/efo/EFO_0008229	GCST004365	Genome-wide genotyping array	NA	NA	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	9p21.3	9	22062135	NR	CDKN2B-AS1	NA	NA	ENSG00000240498	NA	NA	rs1011970-T	rs1011970	0	1011970	intron_variant	FALSE	0.16	5e-7	6.301029995663981	NA	1.05	[1.00-1.09] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.16	1.05	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	6q25.2	6	152115881	ESR1	ESR1	NA	NA	ENSG00000091831	NA	NA	rs2747652-C	rs2747652	0	2747652	intron_variant	FALSE	0.52	2e-18	17.69897000433602	NA	1.098901	[1.08-1.12]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.52	1.098901	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	13q13.1	13	32398489	NR	BRCA2	NA	NA	ENSG00000139618	NA	NA	rs11571833-T	rs11571833	0	11571833	stop_gained	FALSE	0.01	2e-13	12.698970004336019	NA	1.58	[1.35-1.84] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.01	1.58	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	1q32.1	1	202218048	LGR6	LGR6	NA	NA	ENSG00000133067	NA	NA	rs6678914-G	rs6678914	0	6678914	intron_variant	FALSE	0.59	3e-12	11.522878745280337	NA	1.0869565	[1.06-1.11]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.59	1.0869565	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	11q24.3	11	129591276	NR	RPS27P20 - LINC01395	ENSG00000240121	ENSG00000281097	NA	53162	20840	rs11820646-C	rs11820646	0	11820646	regulatory_region_variant	TRUE	0.6	2e-7	6.698970004336019	NA	1.0638298	[1.03-1.1] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.6	1.0638298	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	2p24.1	2	19121042	MIR4757	LINC01376	NA	NA	ENSG00000236204	NA	NA	rs12710696-T	rs12710696	0	12710696	intron_variant	FALSE	0.37	7e-8	7.154901959985743	NA	1.06	[1.04-1.09]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.37	1.06	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	8p11.23	8	37000965	NR	KCNU1 - SMARCE1P4	ENSG00000215262	ENSG00000253650	NA	64840	94185	rs13365225-A	rs13365225	0	13365225	intergenic_variant	TRUE	0.82	1e-10	10	NA	1.1111112	[1.06-1.16] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.82	1.1111112	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	1q32.1	1	204549714	MDM4	MDM4	NA	NA	ENSG00000198625	NA	NA	rs4245739-C	rs4245739	0	4245739	3_prime_UTR_variant	FALSE	0.26	3e-23	22.522878745280337	NA	1.14	[1.11-1.16]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.26	1.14	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	2q35	2	217431785	NR	DIRC3	NA	NA	ENSG00000231672	NA	NA	rs16857609-T	rs16857609	0	16857609	intron_variant	FALSE	0.26	2e-8	7.698970004336019	NA	1.07	[1.03-1.10] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.26	1.07	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	19p13.11	19	17290595	ANKLE1	ANKLE1 - ABHD8	ENSG00000160117	ENSG00000127220	NA	2949	1536	rs67397200-G	rs67397200	0	67397200	intergenic_variant	TRUE	0.32	3e-37	36.52287874528034	NA	1.17	[1.14-1.19]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.32	1.17	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	6q14.1	6	81418669	NR	NA - TENT5A	NA	ENSG00000112773	NA	NA	72770	rs17529111-C	rs17529111	0	17529111	intergenic_variant	TRUE	0.22	2e-6	5.698970004336019	NA	1.06	[1.02-1.10] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.22	1.06	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	16p13.3	16	4056787	ADCY9	ADCY9	NA	NA	ENSG00000162104	NA	NA	rs11076805-C	rs11076805	0	11076805	intron_variant	FALSE	0.75	2e-8	7.698970004336019	NA	1.0869565	[1.05-1.11]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.75	1.0869565	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	2q33.1	2	201316524	NR	FLACC1	NA	NA	ENSG00000155749	NA	NA	rs1830298-C	rs1830298	0	1830298	intron_variant	FALSE	0.28	7e-7	6.154901959985743	NA	1.08	[1.04-1.12] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.28	1.08	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	11q22.3	11	108474789	KDELC2	POGLUT3	NA	NA	ENSG00000178202	NA	NA	rs11374964-G	rs11374964	0	11374964	3_prime_UTR_variant	FALSE	0.58	4e-8	7.3979400086720375	NA	1.0638298	[1.04-1.09]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.58	1.0638298	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	5p15.33	5	1296141	NR	TERT - MIR4457	ENSG00000164362	ENSG00000263670	NA	1073	13169	rs3215401-A	rs3215401	0	3215401	intergenic_variant	TRUE	0.69	6e-21	20.221848749616356	NA	1.1363636	[1.1-1.18] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.69	1.1363636	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	19q12	19	29786822	CCNE1	C19orf12 - CCNE1	ENSG00000131943	ENSG00000105173	NA	71033	25169	rs113701136-T	rs113701136	0	113701136	intergenic_variant	TRUE	0.32	2e-7	6.698970004336019	NA	1.07	[1.04-1.09]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.32	1.07	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	8q24.13	8	123745421	ANXA13	ANXA13 - FAM91A1	ENSG00000104537	ENSG00000176853	NA	8019	23018	rs17350191-T	rs17350191	0	17350191	intergenic_variant	TRUE	0.34	2e-8	7.698970004336019	NA	1.07	[1.04-1.09]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.34	1.07	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	8p23.3	8	220692	RPL23AP53	RPL23AP53	NA	NA	ENSG00000223508	NA	NA	rs66823261-C	rs66823261	0	66823261	intron_variant	FALSE	0.23	6e-9	8.221848749616356	NA	1.09	[1.06-1.12]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.23	1.09	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	11q22.3	11	108486410	KDELC2	POGLUT3	NA	NA	ENSG00000178202	NA	NA	rs74911261-G	rs74911261	0	74911261	missense_variant	FALSE	0.98	2e-6	5.698970004336019	NA	1.2195122	[1.12-1.33]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.98	1.2195122	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	18q12.1	18	32397726	NR	GAREM1	NA	NA	ENSG00000141441	NA	NA	rs117618124-T	rs117618124	0	117618124	intron_variant	FALSE	0.95	5e-6	5.301029995663981	NA	1.1904762	[1.1-1.3] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.95	1.1904762	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	2q35	2	217056046	NR	LINC01921 - RN7SKP43	ENSG00000223874	ENSG00000251982	NA	184403	195510	rs4442975-G	rs4442975	0	4442975	intergenic_variant	TRUE	0.5	3e-6	5.522878745280337	NA	1.0638298	[1.02-1.09] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.5	1.0638298	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer	14,135 European ancestry ER- cases, 58,126 European ancestry controls, 7,784 European ancestry  BRCA1 carrrier cases, 7,782 European ancestry BRCA1 carrrier controls	7,333 European ancestry ER- cases, 42,468 European ancestry controls, 1,630 European ancestry BRCA1 carrrier cases, 1,712 European ancestry BRCA1 carrrier controls	16p13.3	16	4056787	ADCY9	ADCY9	NA	NA	ENSG00000162104	NA	NA	rs11076805-C	rs11076805	0	11076805	intron_variant	FALSE	0.75	1e-8	8	NA	1.0869565	[1.05-1.11] (BCAC)	Illumina [~ 11500000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST005077	Genome-wide genotyping array	0.75	1.0869565	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer	14,135 European ancestry ER- cases, 58,126 European ancestry controls, 7,784 European ancestry  BRCA1 carrrier cases, 7,782 European ancestry BRCA1 carrrier controls	7,333 European ancestry ER- cases, 42,468 European ancestry controls, 1,630 European ancestry BRCA1 carrrier cases, 1,712 European ancestry BRCA1 carrrier controls	6q23.1	6	130027974	L3MBTL3	L3MBTL3	NA	NA	ENSG00000198945	NA	NA	rs6569648-T	rs6569648	0	6569648	intron_variant	FALSE	0.77	8e-10	9.096910013008056	NA	1.0752687	[1.05-1.11] (BCAC)	Illumina [~ 11500000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST005077	Genome-wide genotyping array	0.77	1.0752687	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer	14,135 European ancestry ER- cases, 58,126 European ancestry controls, 7,784 European ancestry  BRCA1 carrrier cases, 7,782 European ancestry BRCA1 carrrier controls	7,333 European ancestry ER- cases, 42,468 European ancestry controls, 1,630 European ancestry BRCA1 carrrier cases, 1,712 European ancestry BRCA1 carrrier controls	11q22.3	11	108474789	KDELC2	POGLUT3	NA	NA	ENSG00000178202	NA	NA	rs11374964-G	rs11374964	0	11374964	3_prime_UTR_variant	FALSE	0.58	4e-13	12.397940008672037	NA	1.0638298	[1.04-1.09] (BCAC)	Illumina [~ 11500000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST005077	Genome-wide genotyping array	0.58	1.0638298	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer	14,135 European ancestry ER- cases, 58,126 European ancestry controls, 7,784 European ancestry  BRCA1 carrrier cases, 7,782 European ancestry BRCA1 carrrier controls	7,333 European ancestry ER- cases, 42,468 European ancestry controls, 1,630 European ancestry BRCA1 carrrier cases, 1,712 European ancestry BRCA1 carrrier controls	18q12.1	18	27821241	CDH2	NA	NA	NA	NA	NA	NA	rs36194942-A	rs36194942	0	36194942	intergenic_variant	TRUE	0.7	1e-8	8	NA	1.0638298	[1.04-1.1] (BCAC)	Illumina [~ 11500000] (imputed)	N	breast carcinoma	http://www.ebi.ac.uk/efo/EFO_0000305	GCST005077	Genome-wide genotyping array	0.7	1.0638298	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	14q24.1	14	68567965	NR	RAD51B	NA	NA	ENSG00000182185	NA	NA	rs999737-C	rs999737	0	999737	intron_variant	FALSE	0.77	3e-8	7.522878745280337	NA	1.0869565	[1.04-1.12] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.77	1.0869565	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	10q21.2	10	62540131	NR	ZNF365 - NA	ENSG00000138311	NA	NA	59843	NA	rs10995201-A	rs10995201	0	10995201	intron_variant	TRUE	0.84	2e-9	8.698970004336019	NA	1.0752687	[1.02-1.12] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.84	1.0752687	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	13q22.1	13	73383544	KLF5	NA - MARK2P12	NA	ENSG00000229708	NA	NA	24224	rs6562760-G	rs6562760	0	6562760	intergenic_variant	TRUE	0.76	9e-10	9.045757490560675	NA	1.0869565	[1.05-1.11]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.76	1.0869565	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	14q32.12	14	92637727	NR	RIN3	NA	NA	ENSG00000100599	NA	NA	rs11627032-T	rs11627032	0	11627032	intron_variant	FALSE	0.75	2e-6	5.698970004336019	NA	1.0526316	[1.01-1.09] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.75	1.0526316	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	2p23.2	2	28897867	WDR43	WDR43	NA	NA	ENSG00000163811	NA	NA	rs4577244-C	rs4577244	0	4577244	intron_variant	FALSE	0.659999999999999	2e-9	8.698970004336019	NA	1.0869565	[1.05-1.11]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.659999999999999	1.0869565	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	8q24.21	8	127343372	NR	CASC8, POU5F1B, PCAT1	NA	NA	ENSG00000246228, ENSG00000212993, ENSG00000253438	NA	NA	rs13281615-G	rs13281615	0	13281615	intron_variant	FALSE	0.41	9e-6	5.045757490560675	NA	1.07	[1.03-1.10] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.41	1.07	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	16q12.2	16	53821379	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs11075995-A	rs11075995	0	11075995	intron_variant	FALSE	0.3	1e-10	10	NA	1.09	[1.06-1.12]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.3	1.09	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	5q33.3	5	158817075	NR	EBF1	NA	NA	ENSG00000164330	NA	NA	rs1432679-C	rs1432679	0	1432679	intron_variant	FALSE	0.43	1e-10	10	NA	1.08	[1.04-1.11] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.43	1.08	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	6q25.1	6	151621059	ESR1	CCDC170	NA	NA	ENSG00000120262	NA	NA	rs3757322-G	rs3757322	0	3757322	3_prime_UTR_variant	FALSE	0.32	3e-31	30.522878745280337	NA	1.15	[1.12-1.18]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.32	1.15	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	12q22	12	95633983	NR	PGAM1P5	NA	NA	ENSG00000257150	NA	NA	rs17356907-A	rs17356907	0	17356907	intron_variant	FALSE	0.7	2e-8	7.698970004336019	NA	1.0638298	[1.03-1.1] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.7	1.0638298	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	5p15.33	5	1279675	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs10069690-T	rs10069690	0	10069690	intron_variant	FALSE	0.26	2e-35	34.69897000433602	NA	1.18	[1.15-1.21]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.26	1.18	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	16q12.2	16	53779455	NR	FTO	NA	NA	ENSG00000140718	NA	NA	rs17817449-T	rs17817449	0	17817449	intron_variant	FALSE	0.59	2e-10	9.698970004336019	NA	1.0752687	[1.04-1.11] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.59	1.0752687	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	6q23.1	6	130027974	L3MBTL3	L3MBTL3	NA	NA	ENSG00000198945	NA	NA	rs6569648-T	rs6569648	0	6569648	intron_variant	FALSE	0.77	4e-8	7.3979400086720375	NA	1.0752687	[1.05-1.11]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.77	1.0752687	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	8q21.13	8	75505702	NR	HNF4G	NA	NA	ENSG00000164749	NA	NA	rs2943559-G	rs2943559	0	2943559	intron_variant	FALSE	0.08	3e-6	5.522878745280337	NA	1.1	[1.04-1.16] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.08	1.1	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	18q12.1	18	27821241	CDH2	NA	NA	NA	NA	NA	NA	rs36194942-A	rs36194942	0	36194942	intergenic_variant	TRUE	0.7	3e-7	6.522878745280337	NA	1.0638298	[1.04-1.1]	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.7	1.0638298	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	19q13.31	19	43782361	NR	KCNN4 - LYPD5	ENSG00000104783	ENSG00000159871	NA	1104	3513	rs3760982-A	rs3760982	0	3760982	regulatory_region_variant	TRUE	0.46	5e-8	7.301029995663981	NA	1.08	[1.05-1.12] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.46	1.08	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	16q12.1	16	52565276	NR	CASC16	NA	NA	ENSG00000249231	NA	NA	rs4784227-T	rs4784227	0	4784227	intron_variant	FALSE	0.24	2e-26	25.69897000433602	NA	1.14	[1.10-1.19] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.24	1.14	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	19p13.11	19	18460331	NR	ELL	NA	NA	ENSG00000105656	NA	NA	rs4808801-A	rs4808801	0	4808801	intron_variant	FALSE	0.659999999999999	6e-6	5.221848749616356	NA	1.0416667	[1.01-1.08] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.659999999999999	1.0416667	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	2q14.2	2	120487546	NR	LINC01101 - NA	ENSG00000280409	NA	NA	21328	NA	rs4849887-C	rs4849887	0	4849887	intergenic_variant	TRUE	0.9	4e-9	8.397940008672037	NA	1.1764705	[1.11-1.23] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.9	1.1764705	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	22q13.1	22	40480230	NR	MRTFA	NA	NA	ENSG00000196588	NA	NA	rs6001930-C	rs6001930	0	6001930	intron_variant	FALSE	0.1	2e-11	10.698970004336019	NA	1.14	[1.08-1.19] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.1	1.14	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	1p36.22	1	10506158	NR	PEX14	NA	NA	ENSG00000142655	NA	NA	rs616488-A	rs616488	0	616488	intron_variant	FALSE	0.669999999999999	4e-18	17.397940008672037	NA	1.1235955	[1.09-1.16] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.669999999999999	1.1235955	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	5q11.2	5	56757896	NR	NA - MAP3K1	NA	ENSG00000095015	NA	NA	57653	rs62355902-T	rs62355902	0	62355902	intergenic_variant	TRUE	0.16	2e-6	5.698970004336019	NA	1.06	[1.02-1.11] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.16	1.06	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	12p11.22	12	28021884	NR	PTHLH - CCDC91	ENSG00000087494	ENSG00000123106	NA	49151	111365	rs7297051-C	rs7297051	0	7297051	TF_binding_site_variant	TRUE	0.76	9e-25	24.045757490560675	NA	1.1494253	[1.1-1.19] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.76	1.1494253	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	10q25.2	10	113014168	NR	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs7904519-G	rs7904519	0	7904519	intron_variant	FALSE	0.46	8e-10	9.096910013008056	NA	1.08	[1.04-1.11] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.46	1.08	NA
2017-12-19	29058716	Milne RL	2017-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29058716	Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Breast cancer (estrogen-receptor negative)	14,135 European ancestry cases, 58,126 European ancestry controls	7,333 European ancestry cases, 42,468 European ancestry controls	6q25.1	6	151631197	NR	CCDC170 - ESR1	ENSG00000120262	ENSG00000091831	NA	10004	25494	rs9397437-A	rs9397437	0	9397437	regulatory_region_variant	TRUE	0.07	3e-40	39.52287874528034	NA	1.32	[1.25-1.40] (Oncoarray)	Illumina [~ 11500000] (imputed)	N	estrogen-receptor negative breast cancer	http://www.ebi.ac.uk/efo/EFO_1000650	GCST005076	Genome-wide genotyping array	0.07	1.32	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	16q12.2	16	53784548	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs3751812-?	rs3751812	0	3751812	intron_variant	FALSE	NR	3e-32	31.522878745280337	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	18q21.32	18	60183864	MC4R	RNU4-17P - NA	ENSG00000202468	NA	NA	20157	NA	rs17782313-?	rs17782313	0	17782313	intergenic_variant	TRUE	NR	3e-13	12.522878745280337	(EA, men)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	72371807	KRT8P21, NEGR1	RPL31P12 - NA	ENSG00000227207	NA	NA	69978	NA	rs11209951-?	rs11209951	0	11209951	intron_variant	TRUE	NR	8e-11	10.096910013008056	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	72478934	KRT8P21, NEGR1	NA	NA	NA	NA	NA	NA	rs7550173-?	rs7550173	0	7550173	intron_variant	TRUE	NR	4e-6	5.3979400086720375	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	74529541	TNNI3K	FPGT-TNNI3K, TNNI3K	NA	NA	ENSG00000259030, ENSG00000116783	NA	NA	rs7551507-?	rs7551507	0	7551507	intron_variant	FALSE	NR	2e-8	7.698970004336019	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	77582646	ZZZ3	ZZZ3	NA	NA	ENSG00000036549	NA	NA	rs17381664-?	rs17381664	0	17381664	intron_variant	FALSE	NR	2e-7	6.698970004336019	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	77998184	DNAJB4	GIPC2, DNAJB4	NA	NA	ENSG00000137960, ENSG00000162616	NA	NA	rs4130548-?	rs4130548	0	4130548	intron_variant	FALSE	NR	5e-9	8.301029995663981	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p31.1	1	78212446	MGC27382	RNFT1P2 - MGC27382	ENSG00000233333	ENSG00000237413	NA	41209	17153	rs12406019-?	rs12406019	0	12406019	intergenic_variant	TRUE	NR	8e-10	9.096910013008056	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p21.3	1	96420711	PTBP2	UBE2WP1 - EEF1A1P11	ENSG00000234422	ENSG00000228502	NA	1778	26219	rs587242-?	rs587242	0	587242	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1p13.3	1	109612066	GNAT2	GNAT2	NA	NA	ENSG00000134183	NA	NA	rs17024393-?	rs17024393	0	17024393	intron_variant	FALSE	NR	1e-9	9	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q25.2	1	177920345	SEC16B	LINC01741 - SEC16B	ENSG00000236720	ENSG00000120341	NA	208070	3611	rs543874-?	rs543874	0	543874	intergenic_variant	TRUE	NR	7e-23	22.154901959985743	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	1q32.1	1	201903136	LMOD1, NAV1	LMOD1	NA	NA	ENSG00000163431	NA	NA	rs2820315-?	rs2820315	0	2820315	intron_variant	FALSE	NR	6e-6	5.221848749616356	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p25.3	2	622827	TMEM18	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	76160	41050	rs2867125-?	rs2867125	0	2867125	intergenic_variant	TRUE	NR	5e-32	31.30102999566398	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p23.3	2	24927247	ADCY3	ADCY3 - DNAJC27	ENSG00000138031	ENSG00000115137	NA	7010	16389	rs6752378-?	rs6752378	0	6752378	intergenic_variant	TRUE	NR	9e-16	15.045757490560675	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p16.1	2	58461772	FLJ30838	LINC01122	NA	NA	ENSG00000233723	NA	NA	rs2075171-?	rs2075171	0	2075171	splice_region_variant	FALSE	NR	3e-7	6.522878745280337	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	2p16.1	2	59102018	LOC730134, FLJ30838	LINC01122 - NA	ENSG00000233723	NA	NA	38252	NA	rs759250-?	rs759250	0	759250	intron_variant	TRUE	NR	5e-8	7.301029995663981	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p14.2	3	61250788	FHIT	FHIT	NA	NA	ENSG00000189283	NA	NA	rs2365389-?	rs2365389	0	2365389	intron_variant	FALSE	NR	6e-6	5.221848749616356	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3p12.1	3	85777586	CADM2	CADM2	NA	NA	ENSG00000175161	NA	NA	rs9852127-?	rs9852127	0	9852127	intron_variant	FALSE	NR	2e-6	5.698970004336019	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q22.3	3	138389241	MRAS	MRAS	NA	NA	ENSG00000158186	NA	NA	rs1720825-?	rs1720825	0	1720825	intron_variant	FALSE	NR	3e-6	5.522878745280337	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	3q27.2	3	186101093	ETV5	ETV5	NA	NA	ENSG00000244405	NA	NA	rs4234589-?	rs4234589	0	4234589	intron_variant	FALSE	NR	3e-13	12.522878745280337	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	4p12	4	45180510	GNPDA2	PRDX4P1 - THAP12P9	ENSG00000248987	ENSG00000248320	NA	235549	142743	rs10938397-?	rs10938397	0	10938397	intergenic_variant	TRUE	NR	1e-10	10	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.31	6	33764010	LEMD2	IP6K3 - LEMD2	ENSG00000161896	ENSG00000161904	NA	17105	7192	rs943466-?	rs943466	0	943466	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.31	6	34471792	PACSIN1	PACSIN1	NA	NA	ENSG00000124507	NA	NA	rs7757419-?	rs7757419	0	7757419	intron_variant	FALSE	NR	1e-6	6	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p21.31	6	34805950	UHRF1BP1	UHRF1BP1	NA	NA	ENSG00000065060	NA	NA	rs2395607-?	rs2395607	0	2395607	intron_variant	FALSE	NR	5e-10	9.301029995663981	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index (joint analysis main effects and physical activity interaction)	2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals	6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men	6p12.3	6	50835337	TFAP2B	TFAP2B	NA	NA	ENSG00000008196	NA	NA	rs987237-?	rs987237	0	987237	intron_variant	FALSE	NR	6e-10	9.221848749616356	(EA, women)	NA	NA	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	physical activity measurement, body mass index	http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004558	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	7p12.2	7	50218107	intergenic	SPATA48 - IKZF1	ENSG00000164500	ENSG00000185811	NA	58851	85961	rs11769630-A	rs11769630	0	11769630	intron_variant	TRUE	0.0748	1e-14	14	NA	0.0532621	[0.04-0.067] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0748	NA	0.0532621
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	7p12.2	7	50330658	IKZF1	IKZF1	NA	NA	ENSG00000185811	NA	NA	rs149007767-T	rs149007767	0	149007767	intron_variant	FALSE	0.1619	9e-13	12.045757490560675	NA	0.03641274	[0.026-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1619	NA	0.03641274
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	7q21.2	7	92779056	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs445-T	rs445	0	445	intron_variant	FALSE	0.0971	2e-12	11.698970004336019	NA	0.04239009	[0.031-0.054] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0971	NA	0.04239009
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	7q36.1	7	150541271	ALDH7A1P3	GIMAP7 - ALDH7A1P3	ENSG00000179144	ENSG00000243853	NA	20198	483	rs939960-A	rs939960	0	939960	intergenic_variant	TRUE	0.2301	2e-10	9.698970004336019	NA	0.02702961	[0.019-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2301	NA	0.02702961
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	8p23.1	8	9326086	RP11-115J16.1	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	38508	45004	rs4841132-G	rs4841132	0	4841132	non_coding_transcript_exon_variant	TRUE	0.9084	3e-11	10.522878745280337	NA	0.04101722	[0.029-0.053] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.9084	NA	0.04101722
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	8p23.1	8	10875395	intergenic	PINX1 - XKR6	ENSG00000258724	ENSG00000171044	NA	35548	20650	rs1864585-G	rs1864585	0	1864585	intergenic_variant	TRUE	0.7434	8e-12	11.096910013008056	NA	0.02791705	[0.02-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.7434	NA	0.02791705
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	8p11.21	8	41774270	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs10099921-C	rs10099921	0	10099921	intron_variant	FALSE	0.6344	1e-11	11	NA	0.02555842	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.6344	NA	0.02555842
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	8q11.21	8	47739071	CEBPD	CEBPD - PRKDC	ENSG00000221869	ENSG00000253729	NA	907	34040	rs45577137-G	rs45577137	0	45577137	regulatory_region_variant	TRUE	0.0461	4e-13	12.397940008672037	NA	0.06475525	[0.047-0.082] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0461	NA	0.06475525
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	8q12.2	8	60733793	CHD7	CHD7	NA	NA	ENSG00000171316	NA	NA	rs35440906-CA	rs35440906	0	35440906	intron_variant	FALSE	0.1869	3e-44	43.52287874528034	NA	0.0639525	[0.055-0.073] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1869	NA	0.0639525
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	8q21.13	8	78744754	IL7	IL7	NA	NA	ENSG00000104432	NA	NA	rs2717547-G	rs2717547	0	2717547	intron_variant	FALSE	0.2505	1e-10	10	NA	0.02673554	[0.019-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2505	NA	0.02673554
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	8q24.13	8	125469835	RP11-136O12.2	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	31432	389886	rs2954021-G	rs2954021	0	2954021	intron_variant	TRUE	0.5053	2e-12	11.698970004336019	NA	0.02513768	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.5053	NA	0.02513768
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	8q24.21	8	129595529	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs16904123-T	rs16904123	0	16904123	intron_variant	FALSE	0.1881	9e-13	12.045757490560675	NA	0.03272001	[0.024-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1881	NA	0.03272001
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	9p24.1	9	4763176	intergenic	AK3 - ECM1P1	ENSG00000147853	ENSG00000270639	NA	21133	5441	rs385893-C	rs385893	0	385893	regulatory_region_variant	TRUE	0.5221	8e-12	11.096910013008056	NA	0.02439011	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.5221	NA	0.02439011
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	9p21.3	9	22145695	intergenic	CDKN2B-AS1 - NA	ENSG00000240498	NA	NA	17592	NA	rs2065500-G	rs2065500	0	2065500	intergenic_variant	TRUE	0.1593	1e-10	10	NA	0.03130231	[0.022-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1593	NA	0.03130231
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	9p13.3	9	34107507	DCAF12	DCAF12	NA	NA	ENSG00000198876	NA	NA	rs11557154-T	rs11557154	0	11557154	missense_variant	FALSE	0.1277	2e-9	8.698970004336019	NA	0.03189868	[0.021-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.1277	NA	0.03189868
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	9q22.1	9	88880220	intergenic	MIR4289 - PCNPP2	ENSG00000265873	ENSG00000225856	NA	134315	90667	rs61750929-T	rs61750929	0	61750929	regulatory_region_variant	TRUE	0.0559	5e-14	13.301029995663981	NA	0.05865074	[0.043-0.074] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0559	NA	0.05865074
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	9q31.3	9	111182787	RP11-202G18.1	RNY4P18 - MIR7702	ENSG00000212409	ENSG00000274263	NA	85374	88369	rs2150052-T	rs2150052	0	2150052	intron_variant	TRUE	0.5063	3e-10	9.522878745280337	NA	0.02252225	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.5063	NA	0.02252225
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	9q34.2	9	134046024	BRD3	BRD3	NA	NA	ENSG00000169925	NA	NA	rs456205-A	rs456205	0	456205	intron_variant	FALSE	0.2607	2e-10	9.698970004336019	NA	0.02581637	[0.018-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.2607	NA	0.02581637
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	10p12.1	10	28531093	WAC-AS1	WAC-AS1	NA	NA	ENSG00000254635	NA	NA	rs3029439-CAA	rs3029439	0	3029439	intron_variant	FALSE	0.7738	5e-10	9.301029995663981	NA	0.02641109	[0.018-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.7738	NA	0.02641109
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	10q11.21	10	45465572	NR	MARCHF8, MARCHF8	NA	NA	ENSG00000165406, ENSG00000278545	NA	NA	rs34731408-T	rs34731408	0	34731408	intron_variant	FALSE	0.0695	7e-10	9.154901959985743	NA	0.04348796	[0.03-0.057] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.0695	NA	0.04348796
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	10q21.3	10	63267850	JMJD1C	JMJD1C	NA	NA	ENSG00000171988	NA	NA	rs10761731-T	rs10761731	0	10761731	intron_variant	FALSE	0.4177	3e-11	10.522878745280337	NA	0.02406048	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.4177	NA	0.02406048
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	10q22.3	10	79285450	ZMIZ1	ZMIZ1	NA	NA	ENSG00000108175	NA	NA	rs1250569-C	rs1250569	0	1250569	intron_variant	FALSE	0.4417	2e-9	8.698970004336019	NA	0.02190282	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.4417	NA	0.02190282
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	10q24.1	10	97209210	ARHGAP19-SLIT1	ARHGAP19-SLIT1	NA	NA	ENSG00000269891	NA	NA	rs9630089-A	rs9630089	0	9630089	intron_variant	FALSE	0.5726	5e-10	9.301029995663981	NA	0.02287186	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.5726	NA	0.02287186
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	11p15.5	11	305619	IFITM2, RP11-326C3.4	IFITM2	NA	NA	ENSG00000185201	NA	NA	rs6421984-C	rs6421984	0	6421984	intron_variant	FALSE	0.513	3e-25	24.522878745280337	NA	0.03705163	[0.03-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.513	NA	0.03705163
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Neutrophil percentage of white cells	171,542 European ancestry individuals	NA	11q23.3	11	119160042	ABCG4	ABCG4	NA	NA	ENSG00000172350	NA	NA	rs674424-C	rs674424	0	674424	intron_variant	FALSE	0.7312	2e-9	8.698970004336019	NA	0.0245625	[0.016-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007990	GCST004633	Genome-wide genotyping array	0.7312	NA	0.0245625
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea trait (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	16p12.3	16	19609052	C16orf62	VPS35L	NA	NA	ENSG00000103544	NA	NA	rs115432071-T	rs115432071	0	115432071	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	0.197	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement	http://www.ebi.ac.uk/efo/EFO_0007817	GCST005051	Genome-wide genotyping array	NA	NA	0.197
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea trait (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	16p12.3	16	19609052	C16orf62	VPS35L	NA	NA	ENSG00000103544	NA	NA	rs115432071-T	rs115432071	0	115432071	intron_variant	FALSE	NA	3e-7	6.522878745280337	(men)	0.346	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement	http://www.ebi.ac.uk/efo/EFO_0007817	GCST005051	Genome-wide genotyping array	NA	NA	0.346
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea trait (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	16p12.1	16	26081195	HS3ST4	HS3ST4	NA	NA	ENSG00000182601	NA	NA	rs4787347-G	rs4787347	0	4787347	intron_variant	FALSE	NA	7e-7	6.154901959985743	(women)	0.067	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement	http://www.ebi.ac.uk/efo/EFO_0007817	GCST005051	Genome-wide genotyping array	NA	NA	0.067
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea trait (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	17p13.1	17	9345288	STX8	STX8	NA	NA	ENSG00000170310	NA	NA	rs112190082-G	rs112190082	0	112190082	intron_variant	FALSE	NA	4e-7	6.3979400086720375	(women)	0.2	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement	http://www.ebi.ac.uk/efo/EFO_0007817	GCST005051	Genome-wide genotyping array	NA	NA	0.2
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea trait (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	17q24.3	17	71948385	Intergenic	NA - ROCR	NA	ENSG00000228639	NA	NA	73466	rs113724004-T	rs113724004	0	113724004	intergenic_variant	TRUE	NA	8e-7	6.096910013008056	(men)	0.123	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement	http://www.ebi.ac.uk/efo/EFO_0007817	GCST005051	Genome-wide genotyping array	NA	NA	0.123
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea trait (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	20p13	20	175501	Intergenic	DEFB127 - DEFB128	ENSG00000088782	ENSG00000185982	NA	16338	12352	rs142002225-T	rs142002225	0	142002225	intergenic_variant	TRUE	NA	3e-7	6.522878745280337	(women)	0.108	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement	http://www.ebi.ac.uk/efo/EFO_0007817	GCST005051	Genome-wide genotyping array	NA	NA	0.108
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea during REM sleep (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	NA	NA	NA	RP4-788P17.1	NA	NA	NA	NA	NA	NA	chr1:74135031-A	chr1:74135031	0	NA	NA	TRUE	NA	1e-6	6	NA	0.31	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement during REM sleep	http://www.ebi.ac.uk/efo/EFO_0008455	GCST005050	Genome-wide genotyping array	NA	NA	0.31
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea during REM sleep (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	4q31.3	4	152638518	TMEM154	TMEM154	NA	NA	ENSG00000170006	NA	NA	rs72956768-G	rs72956768	0	72956768	intron_variant	FALSE	NA	5e-7	6.301029995663981	(men)	0.563	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement during REM sleep	http://www.ebi.ac.uk/efo/EFO_0008455	GCST005050	Genome-wide genotyping array	NA	NA	0.563
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea during REM sleep (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	NA	NA	NA	HUS1, PKD1L1	NA	NA	NA	NA	NA	NA	rs35077018-G	rs35077018	0	35077018	NA	TRUE	NA	8e-7	6.096910013008056	(women)	0.357	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement during REM sleep	http://www.ebi.ac.uk/efo/EFO_0008455	GCST005050	Genome-wide genotyping array	NA	NA	0.357
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea during REM sleep (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	8q24.21	8	126637666	RP11-89K10.1	PCAT1	NA	NA	ENSG00000253438	NA	NA	rs9297743-G	rs9297743	0	9297743	intron_variant	FALSE	NA	9e-7	6.045757490560675	(men)	0.241	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement during REM sleep	http://www.ebi.ac.uk/efo/EFO_0008455	GCST005050	Genome-wide genotyping array	NA	NA	0.241
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea during REM sleep (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	11p15.4	11	10992529	intergenic	ZBED5-AS1 - LINC02752	ENSG00000247271	ENSG00000254401	NA	83557	28354	rs79697311-C	rs79697311	0	79697311	intergenic_variant	TRUE	NA	4e-7	6.3979400086720375	(women)	0.692	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement during REM sleep	http://www.ebi.ac.uk/efo/EFO_0008455	GCST005050	Genome-wide genotyping array	NA	NA	0.692
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea during REM sleep (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	12q23.1	12	96683772	C12orf55	CFAP54	NA	NA	ENSG00000188596	NA	NA	rs201360344-G	rs201360344	1	58936228	intron_variant	FALSE	NA	6e-7	6.221848749616356	NA	0.478	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement during REM sleep	http://www.ebi.ac.uk/efo/EFO_0008455	GCST005050	Genome-wide genotyping array	NA	NA	0.478
2017-12-18	29077507	Chen H	2017-10-27	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/29077507	Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.	Obstructive sleep apnea during REM sleep (apnea hypopnea index)	677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men,  7,492 Hispanic women, 5,065 Hispanic men	NA	15q11.2	15	23793248	intergenic	RNU6-741P - NA	ENSG00000206616	NA	NA	15705	NA	rs41408454-G	rs41408454	0	41408454	intron_variant	TRUE	NA	9e-7	6.045757490560675	(women)	0.523	[NR] unit increase	Affymetrix, Illumina [NR] (imputed)	N	sleep apnea measurement during REM sleep	http://www.ebi.ac.uk/efo/EFO_0008455	GCST005050	Genome-wide genotyping array	NA	NA	0.523
2018-02-02	29082582	Almli LM	2017-10-30	Addict Biol	www.ncbi.nlm.nih.gov/pubmed/29082582	Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.	Problematic alcohol use in trauma-exposed individuals	1,036 African American individuals	828 European ancestry individuals, 108 African ancestry individuals, 282 Hispanic and Native American individuals, 170 other ancestry individuals, 6 Asian individuals	4q28.2	4	129416904	SCLT1	NA	NA	NA	NA	NA	NA	rs1433375-A	rs1433375	0	1433375	intergenic_variant	TRUE	0.17	3e-8	7.522878745280337	(AA, initial)	2.69	[1.75-3.63] unit increase	Illumina [501278]	N	alcohol use disorder measurement, response to trauma exposure	http://www.ebi.ac.uk/efo/EFO_0009458, http://www.ebi.ac.uk/efo/EFO_0008483	GCST005236	Genome-wide genotyping array	0.17	2.69	NA
2018-02-02	29082582	Almli LM	2017-10-30	Addict Biol	www.ncbi.nlm.nih.gov/pubmed/29082582	Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.	Problematic alcohol use in trauma-exposed individuals	1,036 African American individuals	828 European ancestry individuals, 108 African ancestry individuals, 282 Hispanic and Native American individuals, 170 other ancestry individuals, 6 Asian individuals	18q12.1	18	31646245	B4GALT6	B4GALT6	NA	NA	ENSG00000118276	NA	NA	rs1667284-A	rs1667284	0	1667284	intron_variant	FALSE	0.14	4e-6	5.3979400086720375	(AA, initial)	2.2	[1.28-3.12] unit increase	Illumina [501278]	N	alcohol use disorder measurement, response to trauma exposure	http://www.ebi.ac.uk/efo/EFO_0009458, http://www.ebi.ac.uk/efo/EFO_0008483	GCST005236	Genome-wide genotyping array	0.14	2.2	NA
2018-02-02	29082582	Almli LM	2017-10-30	Addict Biol	www.ncbi.nlm.nih.gov/pubmed/29082582	Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.	Problematic alcohol use in trauma-exposed individuals	1,036 African American individuals	828 European ancestry individuals, 108 African ancestry individuals, 282 Hispanic and Native American individuals, 170 other ancestry individuals, 6 Asian individuals	8q24.22	8	133722977	ST3GAL1	Metazoa_SRP - MTND2P7	ENSG00000278007	ENSG00000253970	NA	54276	31834	rs7843718-G	rs7843718	0	7843718	TF_binding_site_variant	TRUE	0.18	5e-6	5.301029995663981	(AA, initial)	1.86	[1.06-2.66] unit increase	Illumina [501278]	N	alcohol use disorder measurement, response to trauma exposure	http://www.ebi.ac.uk/efo/EFO_0009458, http://www.ebi.ac.uk/efo/EFO_0008483	GCST005236	Genome-wide genotyping array	0.18	1.86	NA
2018-02-02	29082582	Almli LM	2017-10-30	Addict Biol	www.ncbi.nlm.nih.gov/pubmed/29082582	Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.	Problematic alcohol use in trauma-exposed individuals	1,036 African American individuals	828 European ancestry individuals, 108 African ancestry individuals, 282 Hispanic and Native American individuals, 170 other ancestry individuals, 6 Asian individuals	20q13.11	20	43125961	PTPRT	PTPRT	NA	NA	ENSG00000196090	NA	NA	rs11086862-C	rs11086862	0	11086862	intron_variant	FALSE	0.44	5e-6	5.301029995663981	(AA, initial)	2	[1.14-2.86] unit increase	Illumina [501278]	N	alcohol use disorder measurement, response to trauma exposure	http://www.ebi.ac.uk/efo/EFO_0009458, http://www.ebi.ac.uk/efo/EFO_0008483	GCST005236	Genome-wide genotyping array	0.44	2	NA
2018-02-02	29082582	Almli LM	2017-10-30	Addict Biol	www.ncbi.nlm.nih.gov/pubmed/29082582	Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.	Problematic alcohol use in trauma-exposed individuals	1,036 African American individuals	828 European ancestry individuals, 108 African ancestry individuals, 282 Hispanic and Native American individuals, 170 other ancestry individuals, 6 Asian individuals	3p26.3	3	47829	CHL1	LINC01986 - CHL1-AS2	ENSG00000223587	ENSG00000224318	NA	22980	61878	rs991639-A	rs991639	0	991639	intergenic_variant	TRUE	0.13	1e-6	6	(AA, initial)	2.24	[1.34-3.14] unit increase	Illumina [501278]	N	alcohol use disorder measurement, response to trauma exposure	http://www.ebi.ac.uk/efo/EFO_0009458, http://www.ebi.ac.uk/efo/EFO_0008483	GCST005236	Genome-wide genotyping array	0.13	2.24	NA
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p13.3	1	109612066	GNAT2	GNAT2	NA	NA	ENSG00000134183	NA	NA	rs17024393-T	rs17024393	0	17024393	intron_variant	FALSE	0.9549	3e-6	5.522878745280337	(men)	0.0641	[0.037-0.091] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.9549	NA	0.0641
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	4p12	4	45180510	GNPDA2	PRDX4P1 - THAP12P9	ENSG00000248987	ENSG00000248320	NA	235549	142743	rs10938397-A	rs10938397	0	10938397	intergenic_variant	TRUE	0.5821	4e-13	12.397940008672037	(men)	0.0346	[0.025-0.044] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.5821	NA	0.0346
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	4p12	4	45180510	GNPDA2	PRDX4P1 - THAP12P9	ENSG00000248987	ENSG00000248320	NA	235549	142743	rs10938397-A	rs10938397	0	10938397	intergenic_variant	TRUE	0.5821	2e-23	22.69897000433602	NA	0.0329	[0.026-0.039] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.5821	NA	0.0329
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	4p12	4	45180510	GNPDA2	PRDX4P1 - THAP12P9	ENSG00000248987	ENSG00000248320	NA	235549	142743	rs10938397-A	rs10938397	0	10938397	intergenic_variant	TRUE	0.5821	2e-13	12.698970004336019	(women)	0.032	[0.024-0.04] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.5821	NA	0.032
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16p12.3	16	19924067	GPR139	GPRC5B - NA	ENSG00000167191	NA	NA	37900	NA	rs12446632-A	rs12446632	0	12446632	intergenic_variant	TRUE	0.1334	2e-9	8.698970004336019	(men)	0.0423	[0.029-0.056] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.1334	NA	0.0423
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16p12.3	16	19924067	GPR139	GPRC5B - NA	ENSG00000167191	NA	NA	37900	NA	rs12446632-A	rs12446632	0	12446632	intergenic_variant	TRUE	0.1334	1e-10	10	NA	0.0328	[0.023-0.043] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.1334	NA	0.0328
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	10q23.1	10	85651147	GRID1	GRID1	NA	NA	ENSG00000182771	NA	NA	rs7899106-A	rs7899106	0	7899106	intron_variant	FALSE	0.9366	3e-6	5.522878745280337	NA	0.0337	[0.02-0.048] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.9366	NA	0.0337
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	18q21.32	18	59216087	GRP	SEC11C - GRP	ENSG00000166562	ENSG00000134443	NA	57255	4071	rs7243357-T	rs7243357	0	7243357	intergenic_variant	TRUE	0.8196	4e-8	7.3979400086720375	NA	0.0232	[0.015-0.031] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.8196	NA	0.0232
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	18q21.32	18	59216087	GRP	SEC11C - GRP	ENSG00000166562	ENSG00000134443	NA	57255	4071	rs7243357-T	rs7243357	0	7243357	intergenic_variant	TRUE	0.8196	1e-6	6	(men)	0.0297	[0.018-0.042] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.8196	NA	0.0297
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q11.23	7	75533848	HIP1	HIP1	NA	NA	ENSG00000127946	NA	NA	rs1167827-A	rs1167827	0	1167827	3_prime_UTR_variant	FALSE	0.4293	5e-6	5.301029995663981	(men)	0.023	[0.013-0.033] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4293	NA	0.023
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	7q11.23	7	75533848	HIP1	HIP1	NA	NA	ENSG00000127946	NA	NA	rs1167827-A	rs1167827	0	1167827	3_prime_UTR_variant	FALSE	0.4293	6e-8	7.221848749616356	NA	0.0199	[0.013-0.027] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4293	NA	0.0199
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	8q21.13	8	75894349	HNF4G	NA	NA	NA	NA	NA	NA	rs17405819-T	rs17405819	0	17405819	intergenic_variant	TRUE	0.7022	7e-8	7.154901959985743	NA	0.019	[0.012-0.026] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.7022	NA	0.019
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q23.3	6	137354404	IFNGR1	HLA-B - NA	ENSG00000206450	NA	NA	105997216	NA	rs13201877-A	rs13201877	0	13201877	regulatory_region_variant	TRUE	0.8661	5e-6	5.301029995663981	NA	0.0221	[0.013-0.032] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.8661	NA	0.0221
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p31.3	1	62129005	INADL	PATJ	NA	NA	ENSG00000132849	NA	NA	rs2481665-T	rs2481665	0	2481665	intron_variant	FALSE	0.561	3e-11	10.522878745280337	(EA)	0.016	[0.012-0.02] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.561	NA	0.016
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2q36.3	2	226228086	IRS1	NYAP2 - MIR5702	ENSG00000144460	ENSG00000263363	NA	574068	430624	rs2176040-A	rs2176040	0	2176040	intergenic_variant	TRUE	0.3557	2e-7	6.698970004336019	(men)	0.0253	[0.016-0.035] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.3557	NA	0.0253
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	19q13.11	19	33818627	KCTD15	KCTD15 - NA	ENSG00000153885	NA	NA	2864	NA	rs29941-A	rs29941	0	29941	intergenic_variant	TRUE	0.3247	1e-8	8	NA	0.0202	[0.013-0.027] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.3247	NA	0.0202
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	17q25.3	17	80641771	KIAA1303	RPTOR	NA	NA	ENSG00000141564	NA	NA	rs12940622-A	rs12940622	0	12940622	intron_variant	FALSE	0.4324	7e-7	6.154901959985743	(men)	0.0232	[0.014-0.032] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4324	NA	0.0232
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	17q25.3	17	80641771	KIAA1303	RPTOR	NA	NA	ENSG00000141564	NA	NA	rs12940622-A	rs12940622	0	12940622	intron_variant	FALSE	0.4324	2e-8	7.698970004336019	NA	0.0178	[0.012-0.024] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4324	NA	0.0178
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9p21.1	9	28414341	LINGO2	LINGO2	NA	NA	ENSG00000174482	NA	NA	rs10968576-A	rs10968576	0	10968576	intron_variant	FALSE	0.6952	9e-10	9.045757490560675	(women)	0.0279	[0.019-0.037] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.6952	NA	0.0279
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9p21.1	9	28414341	LINGO2	LINGO2	NA	NA	ENSG00000174482	NA	NA	rs10968576-A	rs10968576	0	10968576	intron_variant	FALSE	0.6952	3e-13	12.522878745280337	NA	0.0256	[0.019-0.032] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.6952	NA	0.0256
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	9p21.1	9	28414341	LINGO2	LINGO2	NA	NA	ENSG00000174482	NA	NA	rs10968576-A	rs10968576	0	10968576	intron_variant	FALSE	0.6952	7e-6	5.154901959985743	(men)	0.0228	[0.013-0.033] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.6952	NA	0.0228
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q23	15	67784830	MAP2K5	MAP2K5	NA	NA	ENSG00000137764	NA	NA	rs16951275-T	rs16951275	0	16951275	intron_variant	FALSE	0.7478	5e-14	13.301029995663981	NA	0.0281	[0.021-0.035] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.7478	NA	0.0281
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	15q23	15	67784830	MAP2K5	MAP2K5	NA	NA	ENSG00000137764	NA	NA	rs16951275-T	rs16951275	0	16951275	intron_variant	FALSE	0.7478	2e-11	10.698970004336019	(women)	0.0322	[0.023-0.042] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.7478	NA	0.0322
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	18q21.32	18	60161902	MC4R	RPS3AP49 - RNU4-17P	ENSG00000242060	ENSG00000202468	NA	11537	1665	rs6567160-T	rs6567160	0	6567160	intergenic_variant	TRUE	0.7603	1e-31	31	(men)	0.0635	[0.053-0.074] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.7603	NA	0.0635
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	18q21.32	18	60161902	MC4R	RPS3AP49 - RNU4-17P	ENSG00000242060	ENSG00000202468	NA	11537	1665	rs6567160-T	rs6567160	0	6567160	intergenic_variant	TRUE	0.7603	3e-54	53.52287874528034	NA	0.0579	[0.051-0.065] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.7603	NA	0.0579
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p33	1	50094148	ELAVL4	ELAVL4	NA	NA	ENSG00000162374	NA	NA	rs11583200-T	rs11583200	0	11583200	intron_variant	FALSE	0.5794	3e-6	5.522878745280337	NA	0.0161	[0.0094-0.0228] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.5794	NA	0.0161
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p33	1	49124175	ELAVL4	AGBL4	NA	NA	ENSG00000186094	NA	NA	rs657452-A	rs657452	0	657452	intron_variant	FALSE	0.4068	3e-6	5.522878745280337	NA	0.0167	[0.0096-0.0238] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4068	NA	0.0167
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p11.1	3	89096190	EPHA3	GAPDHP50 - EPHA3	ENSG00000241861	ENSG00000044524	NA	47756	11431	rs12629427-C	rs12629427	0	12629427	intergenic_variant	TRUE	0.258	8e-8	7.096910013008056	(AA, women)	0.021	[0.013-0.029] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.258	NA	0.021
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p11.1	3	89093025	EPHA3	GAPDHP50 - EPHA3	ENSG00000241861	ENSG00000044524	NA	44591	14596	rs2173039-C	rs2173039	0	2173039	intergenic_variant	TRUE	0.258	2e-9	8.698970004336019	(EA, women)	0.024	[0.016-0.032] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.258	NA	0.024
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2q34	2	212548507	ERBB4	ERBB4 - NA	ENSG00000178568	NA	NA	9666	NA	rs7599312-A	rs7599312	0	7599312	regulatory_region_variant	TRUE	0.2807	2e-7	6.698970004336019	(women)	0.0272	[0.017-0.037] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.2807	NA	0.0272
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2q34	2	212548507	ERBB4	ERBB4 - NA	ENSG00000178568	NA	NA	9666	NA	rs7599312-A	rs7599312	0	7599312	regulatory_region_variant	TRUE	0.2807	3e-11	10.522878745280337	NA	0.0252	[0.018-0.033] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.2807	NA	0.0252
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q27.2	3	186106215	ETV5	DGKG, ETV5	NA	NA	ENSG00000058866, ENSG00000244405	NA	NA	rs1516725-T	rs1516725	0	1516725	intron_variant	FALSE	0.1363	2e-11	10.698970004336019	(women)	0.0408	[0.029-0.053] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.1363	NA	0.0408
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3q27.2	3	186106215	ETV5	DGKG, ETV5	NA	NA	ENSG00000058866, ENSG00000244405	NA	NA	rs1516725-T	rs1516725	0	1516725	intron_variant	FALSE	0.1363	6e-15	14.221848749616356	NA	0.0367	[0.027-0.046] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.1363	NA	0.0367
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q13.12	12	49853685	FAIM2	BCDIN3D - RPL35AP28	ENSG00000186666	ENSG00000242041	NA	10579	9488	rs7138803-A	rs7138803	0	7138803	intergenic_variant	TRUE	0.3705	3e-8	7.522878745280337	(men)	0.027	[0.017-0.037] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.3705	NA	0.027
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q13.12	12	49853685	FAIM2	BCDIN3D - RPL35AP28	ENSG00000186666	ENSG00000242041	NA	10579	9488	rs7138803-A	rs7138803	0	7138803	intergenic_variant	TRUE	0.3705	4e-16	15.397940008672037	NA	0.029	[0.022-0.036] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.3705	NA	0.029
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	12q13.12	12	49853685	FAIM2	BCDIN3D - RPL35AP28	ENSG00000186666	ENSG00000242041	NA	10579	9488	rs7138803-A	rs7138803	0	7138803	intergenic_variant	TRUE	0.3705	7e-10	9.154901959985743	(women)	0.0301	[0.02-0.04] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.3705	NA	0.0301
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	11q23.3	11	115151684	FAM55B	NA - CADM1	NA	ENSG00000182985	NA	NA	17534	rs12286929-A	rs12286929	0	12286929	intergenic_variant	TRUE	0.4783	4e-8	7.3979400086720375	NA	0.0175	[0.011-0.024] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4783	NA	0.0175
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p14.2	3	61250788	FHIT	FHIT	NA	NA	ENSG00000189283	NA	NA	rs2365389-T	rs2365389	0	2365389	intron_variant	FALSE	0.4348	2e-10	9.698970004336019	(men)	0.0319	[0.022-0.042] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4348	NA	0.0319
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p14.2	3	61250788	FHIT	FHIT	NA	NA	ENSG00000189283	NA	NA	rs2365389-T	rs2365389	0	2365389	intron_variant	FALSE	0.4348	4e-15	14.397940008672037	NA	0.0266	[0.02-0.033] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4348	NA	0.0266
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	3p14.2	3	61250788	FHIT	FHIT	NA	NA	ENSG00000189283	NA	NA	rs2365389-T	rs2365389	0	2365389	intron_variant	FALSE	0.4348	3e-7	6.522878745280337	(women)	0.0225	[0.014-0.031] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4348	NA	0.0225
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	2q24.3	2	163711179	FIGN	FIGN	NA	NA	ENSG00000182263	NA	NA	rs1460676-T	rs1460676	0	1460676	intron_variant	FALSE	0.8195	2e-6	5.698970004336019	NA	0.02	[0.012-0.028] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.8195	NA	0.02
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	6q21	6	108656460	FOXO3	FOXO3	NA	NA	ENSG00000118689	NA	NA	rs9400239-T	rs9400239	0	9400239	5_prime_UTR_variant	FALSE	0.3467	2e-6	5.698970004336019	NA	0.0163	[0.0096-0.023] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.3467	NA	0.0163
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16q12.2	16	53769662	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs1558902-A	rs1558902	0	1558902	intron_variant	FALSE	0.4028	5e-59	58.30102999566398	(women)	0.0707	[0.062-0.079] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4028	NA	0.0707
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16q12.2	16	53769662	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs1558902-A	rs1558902	0	1558902	intron_variant	FALSE	0.4028	3e-110	109.52287874528034	NA	0.075	[0.068-0.082] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4028	NA	0.075
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	16q12.2	16	53769662	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs1558902-A	rs1558902	0	1558902	intron_variant	FALSE	0.4028	7e-65	64.15490195998575	(men)	0.0806	[0.071-0.09] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.4028	NA	0.0806
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p31.1	1	77981077	FUBP1	GIPC2, DNAJB4	NA	NA	ENSG00000137960, ENSG00000162616	NA	NA	rs12401738-A	rs12401738	0	12401738	intron_variant	FALSE	0.339	9e-8	7.045757490560675	NA	0.0184	[0.012-0.025] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.339	NA	0.0184
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p31.1	1	77981077	FUBP1	GIPC2, DNAJB4	NA	NA	ENSG00000137960, ENSG00000162616	NA	NA	rs12401738-A	rs12401738	0	12401738	intron_variant	FALSE	0.339	4e-6	5.3979400086720375	(women)	0.0208	[0.012-0.03] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.339	NA	0.0208
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	5q33.2	5	154158333	GALNT10	MFAP3	NA	NA	ENSG00000037749	NA	NA	rs7715256-T	rs7715256	0	7715256	non_coding_transcript_exon_variant	FALSE	0.574	4e-6	5.3979400086720375	NA	0.0151	[0.0086-0.0216] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.574	NA	0.0151
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p13.3	1	109612066	GNAT2	GNAT2	NA	NA	ENSG00000134183	NA	NA	rs17024393-T	rs17024393	0	17024393	intron_variant	FALSE	0.9549	8e-9	8.096910013008056	(women)	0.0661	[0.044-0.089] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.9549	NA	0.0661
2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	1p13.3	1	109612066	GNAT2	GNAT2	NA	NA	ENSG00000134183	NA	NA	rs17024393-T	rs17024393	0	17024393	intron_variant	FALSE	0.9549	5e-13	12.301029995663981	NA	0.0656	[0.048-0.083] kg/m2 decrease	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N	smoking behavior, body mass index	http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340	GCST004495	Genome-wide genotyping array	0.9549	NA	0.0656
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	4p12	4	45180510	GNPDA2	PRDX4P1 - THAP12P9	ENSG00000248987	ENSG00000248320	NA	235549	142743	rs10938397-G	rs10938397	0	10938397	intergenic_variant	TRUE	0.4312	3e-8	7.522878745280337	(EA,women)	0.0306	[0.02-0.041] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.43120000000000003	NA	0.0306
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	6p21.31	6	34471792	PACSIN1	PACSIN1	NA	NA	ENSG00000124507	NA	NA	rs7757419-T	rs7757419	0	7757419	intron_variant	FALSE	0.18710000000000004	9e-6	5.045757490560675	(EA,women)	0.032	[0.018-0.046] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.18710000000000004	NA	0.032
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	6p21.31	6	34805950	UHRF1BP1	UHRF1BP1	NA	NA	ENSG00000065060	NA	NA	rs2395607-T	rs2395607	0	2395607	intron_variant	FALSE	0.172	2e-7	6.698970004336019	(EA,women)	0.0397	[0.025-0.055] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.172	NA	0.0397
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	6p12.3	6	50835337	TFAP2B	TFAP2B	NA	NA	ENSG00000008196	NA	NA	rs987237-G	rs987237	0	987237	intron_variant	FALSE	0.1856	7e-10	9.154901959985743	(EA,women)	0.042	[0.029-0.055] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.1856	NA	0.042
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	6q26	6	162612318	PARK2	PRKN	NA	NA	ENSG00000185345	NA	NA	rs13191362-A	rs13191362	0	13191362	intron_variant	FALSE	0.878	8e-6	5.096910013008056	(EA,women)	0.0365	[0.02-0.053] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.878	NA	0.0365
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	9q33.1	9	117616205	ASTN2, TLR4	NA - RPL35AP22	NA	ENSG00000235133	NA	NA	69049	rs1928295-T	rs1928295	0	1928295	intergenic_variant	TRUE	0.5482	9e-6	5.045757490560675	(EA,women)	0.0235	[0.013-0.034] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.5482	NA	0.0235
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	11p15.4	11	8666469	TRIM66, STK33, RPL27A	TRIM66	NA	NA	ENSG00000166436	NA	NA	rs7113874-C	rs7113874	0	7113874	intron_variant	FALSE	0.6441	1e-7	7	(EA,women)	0.0292	[0.018-0.04] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.6441	NA	0.0292
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	11p14.1	11	27706992	BDNF	BDNF	NA	NA	ENSG00000176697	NA	NA	rs2030323-C	rs2030323	0	2030323	intron_variant	FALSE	0.7858	7e-9	8.154901959985743	(EA,women)	0.0373	[0.025-0.05] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.7858	NA	0.0373
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	12q13.12	12	49853685	BCDIN3D, FAIM2	BCDIN3D - RPL35AP28	ENSG00000186666	ENSG00000242041	NA	10579	9488	rs7138803-A	rs7138803	0	7138803	intergenic_variant	TRUE	0.3842	1e-8	8	(EA,women)	0.0311	[0.021-0.042] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.3842	NA	0.0311
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	14q12	14	29216122	PRKD1, MIR548AI	NA	NA	NA	NA	NA	NA	rs974471-A	rs974471	0	974471	intron_variant	TRUE	0.756	4e-6	5.3979400086720375	(EA,women)	0.0314	[0.018-0.045] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.756	NA	0.0314
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	14q31.1	14	79433111	NRXN3	NRXN3	NA	NA	ENSG00000021645	NA	NA	rs7141420-T	rs7141420	0	7141420	intron_variant	FALSE	0.5275	1e-8	8	(EA,women)	0.0306	[0.02-0.041] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.5275	NA	0.0306
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	15q23	15	67784061	MAP2K5	MAP2K5	NA	NA	ENSG00000137764	NA	NA	rs8025790-G	rs8025790	0	8025790	intron_variant	FALSE	0.781	2e-8	7.698970004336019	(EA,women)	0.036	[0.023-0.049] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.781	NA	0.036
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	16p13.3	16	3963466	ADCY9	ADCY9	NA	NA	ENSG00000162104	NA	NA	rs2531995-T	rs2531995	0	2531995	3_prime_UTR_variant	FALSE	0.6122	3e-6	5.522878745280337	(EA,women)	0.0288	[0.017-0.041] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.6122	NA	0.0288
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	16p11.2	16	28837347	SH2B1, ATXN2L	ATXN2L - TUFM	ENSG00000168488	ENSG00000178952	NA	110	5064	rs12325113-C	rs12325113	0	12325113	intron_variant	TRUE	0.39449999999999996	2e-7	6.698970004336019	(EA,women)	0.0282	[0.018-0.039] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.39449999999999996	NA	0.0282
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	16q12.2	16	53766065	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs9930333-G	rs9930333	0	9930333	intron_variant	FALSE	0.4327	2e-43	42.69897000433602	(EA,women)	0.0763	[0.066-0.087] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.4327	NA	0.0763
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	18q21.32	18	60192330	MC4R	RNU4-17P - NA	ENSG00000202468	NA	NA	28623	NA	rs12969709-A	rs12969709	0	12969709	intergenic_variant	TRUE	0.2662	5e-21	20.30102999566398	(EA,women)	0.0563	[0.045-0.068] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.2662	NA	0.0563
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	19q13.11	19	33829949	KCTD15	KCTD15 - RN7SL150P	ENSG00000153885	ENSG00000240626	NA	14186	97415	rs2546057-C	rs2546057	0	2546057	intergenic_variant	TRUE	0.4717	3e-6	5.522878745280337	(EA,women)	0.0252	[0.015-0.036] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.4717	NA	0.0252
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p31.1	1	72371807	KRT8P21, NEGR1	RPL31P12 - NA	ENSG00000227207	NA	NA	69978	NA	rs11209951-T	rs11209951	0	11209951	intron_variant	TRUE	0.6168	2e-11	10.698970004336019	(EA)	0.0289	[0.02-0.037] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.6168	NA	0.0289
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p31.1	1	72478934	KRT8P21, NEGR1	NA	NA	NA	NA	NA	NA	rs7550173-T	rs7550173	0	7550173	intron_variant	TRUE	0.6402	2e-10	9.698970004336019	(EA)	0.0281	[0.019-0.037] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.6402	NA	0.0281
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p31.1	1	74529541	TNNI3K	FPGT-TNNI3K, TNNI3K	NA	NA	ENSG00000259030, ENSG00000116783	NA	NA	rs7551507-C	rs7551507	0	7551507	intron_variant	FALSE	0.44299999999999995	4e-8	7.3979400086720375	(EA)	0.0229	[0.015-0.031] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.44299999999999995	NA	0.0229
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p31.1	1	77582646	ZZZ3	ZZZ3	NA	NA	ENSG00000036549	NA	NA	rs17381664-C	rs17381664	0	17381664	intron_variant	FALSE	0.3883	2e-7	6.698970004336019	(EA)	0.0223	[0.014-0.031] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.3883	NA	0.0223
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p31.1	1	77998184	DNAJB4	GIPC2, DNAJB4	NA	NA	ENSG00000137960, ENSG00000162616	NA	NA	rs4130548-C	rs4130548	0	4130548	intron_variant	FALSE	0.3538	8e-7	6.096910013008056	(EA)	0.0214	[0.013-0.03] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.3538	NA	0.0214
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p31.1	1	78212446	MGC27382	RNFT1P2 - MGC27382	ENSG00000233333	ENSG00000237413	NA	41209	17153	rs12406019-G	rs12406019	0	12406019	intergenic_variant	TRUE	0.44930000000000003	3e-7	6.522878745280337	(EA)	0.0214	[0.013-0.03] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.44930000000000003	NA	0.0214
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1p13.3	1	109612066	GNAT2	GNAT2	NA	NA	ENSG00000134183	NA	NA	rs17024393-C	rs17024393	0	17024393	intron_variant	FALSE	0.039100000000000024	9e-13	12.045757490560675	(EA)	0.0831	[0.06-0.106] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.039100000000000024	NA	0.0831
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1q25.2	1	177883445	SEC16B	LINC01741 - SEC16B	ENSG00000236720	ENSG00000120341	NA	171170	40511	rs633715-C	rs633715	0	633715	intron_variant	TRUE	0.19810000000000005	2e-21	20.69897000433602	(EA)	0.0505	[0.04-0.061] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.19810000000000005	NA	0.0505
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	1q32.1	1	201903136	LMOD1, NAV1	LMOD1	NA	NA	ENSG00000163431	NA	NA	rs2820315-T	rs2820315	0	2820315	intron_variant	FALSE	0.3073	7e-9	8.154901959985743	(EA)	0.0257	[0.017-0.034] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.3073	NA	0.0257
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	2p25.3	2	622827	TMEM18	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	76160	41050	rs2867125-C	rs2867125	0	2867125	intergenic_variant	TRUE	0.8253	1e-33	33	(EA)	0.0667	[0.056-0.077] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.8253	NA	0.0667
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	2p23.3	2	24927247	ADCY3	ADCY3 - DNAJC27	ENSG00000138031	ENSG00000115137	NA	7010	16389	rs6752378-A	rs6752378	0	6752378	intergenic_variant	TRUE	0.4628	4e-15	14.397940008672037	(EA)	0.0332	[0.025-0.041] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.4628	NA	0.0332
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	2p16.1	2	58461772	FLJ30838	LINC01122	NA	NA	ENSG00000233723	NA	NA	rs2075171-G	rs2075171	0	2075171	splice_region_variant	FALSE	0.7617	4e-7	6.3979400086720375	(EA)	0.0258	[0.016-0.036] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.7617	NA	0.0258
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	2p16.1	2	59102018	LOC730134, FLJ30838	LINC01122 - NA	ENSG00000233723	NA	NA	38252	NA	rs759250-A	rs759250	0	759250	intron_variant	TRUE	0.286	1e-7	7	(EA)	0.0279	[0.018-0.038] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.286	NA	0.0279
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	3p24.2	3	25058285	LOC100129045, RARB	RNA5SP125 - NA	ENSG00000201713	NA	NA	33159	NA	rs10510554-C	rs10510554	0	10510554	intron_variant	TRUE	0.5714	4e-6	5.3979400086720375	(EA)	0.0192	[0.011-0.027] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.5714	NA	0.0192
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	3p14.2	3	61250788	FHIT	FHIT	NA	NA	ENSG00000189283	NA	NA	rs2365389-C	rs2365389	0	2365389	intron_variant	FALSE	0.5858	5e-12	11.301029995663981	(EA)	0.0291	[0.021-0.037] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.5858	NA	0.0291
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	3p12.1	3	85777586	CADM2	CADM2	NA	NA	ENSG00000175161	NA	NA	rs9852127-A	rs9852127	0	9852127	intron_variant	FALSE	0.1865	1e-7	7	(EA)	0.0295	[0.019-0.04] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.1865	NA	0.0295
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	3q23	3	141587171	RASA2	RASA2	NA	NA	ENSG00000155903	NA	NA	rs2035935-G	rs2035935	0	2035935	intron_variant	FALSE	0.06540000000000001	5e-7	6.301029995663981	(EA)	0.0423	[0.026-0.059] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.06540000000000001	NA	0.0423
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	3q27.2	3	186096853	ETV5	ETV5	NA	NA	ENSG00000244405	NA	NA	rs6809651-G	rs6809651	0	6809651	intron_variant	FALSE	0.8709	9e-13	12.045757490560675	(EA)	0.0447	[0.033-0.057] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.8709	NA	0.0447
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	4p12	4	45180510	GNPDA2	PRDX4P1 - THAP12P9	ENSG00000248987	ENSG00000248320	NA	235549	142743	rs10938397-G	rs10938397	0	10938397	intergenic_variant	TRUE	0.4333	3e-14	13.522878745280337	(EA)	0.0328	[0.024-0.041] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.4333	NA	0.0328
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	4q24	4	102267552	SLC39A8	SLC39A8	NA	NA	ENSG00000138821	NA	NA	rs13107325-T	rs13107325	0	13107325	missense_variant	FALSE	0.0765	1e-9	9	(EA)	0.0531	[0.036-0.07] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.0765	NA	0.0531
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	5q13.3	5	75719417	C5orf37, POC5	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078	NA	1969	33153	rs2112347-T	rs2112347	0	2112347	intergenic_variant	TRUE	0.629	2e-8	7.698970004336019	(EA)	0.024	[0.016-0.032] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.629	NA	0.024
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	5q14.3	5	88401716	LOC645323	TMEM161B-AS1	NA	NA	ENSG00000247828	NA	NA	rs6870983-C	rs6870983	0	6870983	intron_variant	FALSE	0.7798	7e-7	6.154901959985743	(EA)	0.0246	[0.015-0.034] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.7798	NA	0.0246
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	5q21.3	5	108103311	FBXL17	FBXL17	NA	NA	ENSG00000145743	NA	NA	rs40067-G	rs40067	0	40067	intron_variant	FALSE	0.8333	1e-6	6	(EA)	0.0325	[0.019-0.046] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.8333	NA	0.0325
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	5q23.2	5	124994829	LOC644659, ZNF608	LINC02240	NA	NA	ENSG00000260192	NA	NA	rs6864049-G	rs6864049	0	6864049	intron_variant	FALSE	0.5315	3e-8	7.522878745280337	(EA)	0.0231	[0.015-0.031] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.5315	NA	0.0231
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	6p21.31	6	34471792	PACSIN1	PACSIN1	NA	NA	ENSG00000124507	NA	NA	rs7757419-T	rs7757419	0	7757419	intron_variant	FALSE	0.1856	2e-6	5.698970004336019	(EA)	0.027	[0.016-0.038] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.1856	NA	0.027
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	6p21.31	6	34805950	UHRF1BP1	UHRF1BP1	NA	NA	ENSG00000065060	NA	NA	rs2395607-T	rs2395607	0	2395607	intron_variant	FALSE	0.1724	4e-6	5.3979400086720375	(EA)	0.0282	[0.016-0.04] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.1724	NA	0.0282
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	6p12.3	6	50835337	TFAP2B	TFAP2B	NA	NA	ENSG00000008196	NA	NA	rs987237-G	rs987237	0	987237	intron_variant	FALSE	0.18620000000000003	6e-13	12.221848749616356	(EA)	0.0386	[0.028-0.049] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.18620000000000003	NA	0.0386
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	6q26	6	162612318	PARK2	PRKN	NA	NA	ENSG00000185345	NA	NA	rs13191362-A	rs13191362	0	13191362	intron_variant	FALSE	0.8789	3e-7	6.522878745280337	(EA)	0.0328	[0.02-0.045] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.8789	NA	0.0328
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	7q11.23	7	76980627	UPK3B, PMS2L11	DTX2P1, DTX2P1-UPK3BP1-PMS2P11	NA	NA	ENSG00000186704, ENSG00000265479	NA	NA	rs2430307-T	rs2430307	0	2430307	non_coding_transcript_exon_variant	FALSE	0.1792	5e-6	5.301029995663981	(EA)	0.0369	[0.021-0.053] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.1792	NA	0.0369
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	8q21.13	8	75894349	HNF4G	NA	NA	NA	NA	NA	NA	rs17405819-T	rs17405819	0	17405819	intergenic_variant	TRUE	0.6998	4e-6	5.3979400086720375	(EA)	0.0206	[0.012-0.029] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.6998	NA	0.0206
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	9p21.1	9	28415514	LINGO2	LINGO2	NA	NA	ENSG00000174482	NA	NA	rs10968577-T	rs10968577	0	10968577	intron_variant	FALSE	0.3223	1e-11	11	(EA)	0.0315	[0.022-0.041] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.3223	NA	0.0315
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	9q33.1	9	117616205	ASTN2, TLR4	NA - RPL35AP22	NA	ENSG00000235133	NA	NA	69049	rs1928295-T	rs1928295	0	1928295	intergenic_variant	TRUE	0.547	1e-7	7	(EA)	0.022	[0.014-0.03] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.547	NA	0.022
2017-08-18	28448500	Graff M	2017-04-27	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	Body mass index in physically active individuals	1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals	4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men	11p15.4	11	8617653	TRIM66, STK33, RPL27A	TRIM66	NA	NA	ENSG00000166436	NA	NA	rs4929923-C	rs4929923	0	4929923	3_prime_UTR_variant	FALSE	0.6341	1e-8	8	(EA)	0.0245	[0.016-0.033] kg/m2 increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004559	Genome-wide genotyping array	0.6341	NA	0.0245
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	1q23.1	1	158627717	NR	SPTA1	NA	NA	ENSG00000163554	NA	NA	rs3737515-?	rs3737515	0	3737515	missense_variant	FALSE	NR	7e-6	5.154901959985743	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	1q32.1	1	199038079	NR	LINC01221	NA	NA	ENSG00000235492	NA	NA	rs7529925-?	rs7529925	0	7529925	intron_variant	FALSE	NR	1e-7	7	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	1q32.1	1	205280322	NR	TMCC2	NA	NA	ENSG00000133069	NA	NA	rs9660992-?	rs9660992	0	9660992	intron_variant	FALSE	NR	5e-6	5.301029995663981	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	3p24.2	3	24309320	NR	THRB	NA	NA	ENSG00000151090	NA	NA	rs9310736-?	rs9310736	0	9310736	intron_variant	FALSE	NR	8e-10	9.096910013008056	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	3q23	3	142637084	NR	PLS1	NA	NA	ENSG00000120756	NA	NA	rs7615316-?	rs7615316	0	7615316	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	6q26	6	164055994	NR	NA	NA	NA	NA	NA	NA	rs9356181-?	rs9356181	0	9356181	intergenic_variant	TRUE	NR	6e-7	6.221848749616356	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	9q34.2	9	133255935	ABO	ABO, ABO	NA	NA	ENSG00000175164, ENSG00000281879	NA	NA	rs8176746-?	rs8176746	0	8176746	missense_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	9q34.2	9	133279294	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	3270	23176	rs495828-T	rs495828	0	495828	intergenic_variant	TRUE	NR	2e-10	9.698970004336019	(Asian)	0.1033	[0.072-0.135] grams/deciliter decrease	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	0.1033
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	22q12.3	22	37073551	TMPRSS6	TMPRSS6	NA	NA	ENSG00000187045	NA	NA	rs4820268-A	rs4820268	0	4820268	missense_variant	FALSE	NR	2e-9	8.698970004336019	(Asian)	0.0872	[0.059-0.116] grams/deciliter increase	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	0.0872
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	7q36.1	7	151716108	TFR2, ACTL6B, IKZF1, PRKAG2	PRKAG2	NA	NA	ENSG00000106617	NA	NA	rs10224210-?	rs10224210	0	10224210	intron_variant	FALSE	NR	3e-12	11.522878745280337	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	19p13.3	19	2175892	NR	DOT1L	NA	NA	ENSG00000104885	NA	NA	rs12982593-?	rs12982593	0	12982593	intron_variant	FALSE	NR	9e-7	6.045757490560675	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	2p21	2	46128709	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs13008603-?	rs13008603	0	13008603	intron_variant	FALSE	NR	1e-20	20	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	10q22.1	10	69333636	HK1	HK1	NA	NA	ENSG00000156515	NA	NA	rs16926246-?	rs16926246	0	16926246	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	12q24.12	12	111446804	SH2B3	SH2B3, ATXN2	NA	NA	ENSG00000111252, ENSG00000204842	NA	NA	rs3184504-?	rs3184504	0	3184504	missense_variant	FALSE	NR	1e-10	10	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	9q34.2	9	133279294	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	3270	23176	rs495828-?	rs495828	0	495828	intergenic_variant	TRUE	NR	1e-19	19	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	6p22.1	6	27893892	NR	H2BC17 - RNU7-26P	ENSG00000274641	ENSG00000238610	NA	1	3612	rs13219787-?	rs13219787	0	13219787	regulatory_region_variant	TRUE	NR	1e-8	8	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	16p13.3	16	248589	ITFG3	FAM234A	NA	NA	ENSG00000167930	NA	NA	rs13339636-?	rs13339636	0	13339636	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	6p22.2	6	26107235	HFE, HIST1H1T	H4C3 - H1-6	ENSG00000197061	ENSG00000187475	NA	2898	177	rs198846-?	rs198846	0	198846	intergenic_variant	TRUE	NR	1e-8	8	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	7q22.1	7	100642673	TFR2, ACTL6B	TFR2	NA	NA	ENSG00000106327	NA	NA	rs2075672-?	rs2075672	0	2075672	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	4q12	4	54528005	KIT	NA - LINC02260	NA	ENSG00000250456	NA	NA	75206	rs218237-?	rs218237	0	218237	intergenic_variant	TRUE	NR	1e-8	8	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Hemoglobin levels	up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals.	16,389 European and African American individuals	22q12.3	22	37074184	TMPRSS6	TMPRSS6	NA	NA	ENSG00000187045	NA	NA	rs2413450-?	rs2413450	0	2413450	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	Affymetrix, Illumina [2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004005	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	5p15.33	5	1107313	NR	SLC12A7, SLC12A7	NA	NA	ENSG00000113504, ENSG00000276482	NA	NA	rs4535497-A	rs4535497	0	4535497	intron_variant	FALSE	NR	3e-8	7.522878745280337	(Asian)	0.0019	[0.0013-0.0025] unit decrease	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	0.0019
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	6q23.3	6	135090090	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs9376090-T	rs9376090	0	9376090	intron_variant	FALSE	NR	5e-9	8.301029995663981	(Asian)	0.0019	[0.0013-0.0025] unit decrease	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	0.0019
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	16q24.3	16	88783013	CDT1	PIEZO1	NA	NA	ENSG00000103335	NA	NA	rs2608604-A	rs2608604	0	2608604	intron_variant	FALSE	NR	2e-9	8.698970004336019	(Asian)	0.0019	[0.0013-0.0025] unit increase	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	0.0019
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	19p13.3	19	1104079	GPX4	GPX4	NA	NA	ENSG00000167468	NA	NA	rs4807542-A	rs4807542	0	4807542	synonymous_variant	FALSE	0.1694	1e-11	11	NA	0.0327061	[0.023-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.1694	NA	0.0327061
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	19q13.33	19	48955005	BAX	BAX	NA	NA	ENSG00000087088	NA	NA	rs4645881-T	rs4645881	0	4645881	non_coding_transcript_exon_variant	FALSE	0.8535	1e-10	10	NA	0.03286422	[0.023-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.8535	NA	0.03286422
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	19p13.3	19	3179519	S1PR4	S1PR4	NA	NA	ENSG00000125910	NA	NA	rs61731111-T	rs61731111	0	61731111	missense_variant	FALSE	0.0111	1e-16	16	NA	0.1410479	[0.11-0.17] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0111	NA	0.1410479
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	NA	NA	NA	S1PR4	NA	NA	NA	NA	NA	NA	chr19:3179884-T	chr19:3179884	0	NA	NA	TRUE	0.0069	3e-10	9.522878745280337	NA	0.1447753	[0.1-0.19] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0069	NA	0.1447753
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	19p13.11	19	16316300	CTD-2562J15.6	KLF2-DT	NA	NA	ENSG00000267275	NA	NA	rs410867-G	rs410867	0	410867	intron_variant	FALSE	0.2164	2e-43	42.69897000433602	NA	0.06002551	[0.052-0.069] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.2164	NA	0.06002551
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	NA	NA	NA	CTD-2562J15.6	NA	NA	NA	NA	NA	NA	chr19:16430149-A	chr19:16430149	0	NA	NA	TRUE	0.1734	1e-47	47	NA	0.06876845	[0.059-0.078] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.1734	NA	0.06876845
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q13	2	111630955	intergenic	ANAPC1	NA	NA	ENSG00000153107	NA	NA	rs4848100-T	rs4848100	0	4848100	non_coding_transcript_exon_variant	FALSE	0.768	2e-13	12.698970004336019	NA	0.03142982	[0.023-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.768	NA	0.03142982
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q34	2	212959321	AC079610.1	MIR4776-1 - IKZF2	ENSG00000266354	ENSG00000030419	NA	32985	40370	rs12619285-G	rs12619285	0	12619285	intron_variant	TRUE	0.265	6e-53	52.221848749616356	NA	0.06186025	[0.054-0.07] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.265	NA	0.06186025
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q34	2	213033508	IKZF2	IKZF2	NA	NA	ENSG00000030419	NA	NA	rs1586068-G	rs1586068	0	1586068	intron_variant	FALSE	0.9174	2e-15	14.698970004336019	NA	0.05173529	[0.039-0.065] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.9174	NA	0.05173529
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q37.1	2	230257375	SP140	SP140	NA	NA	ENSG00000079263	NA	NA	rs35643768-C	rs35643768	0	35643768	intron_variant	FALSE	0.2523	1e-10	10	NA	0.02628287	[0.018-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.2523	NA	0.02628287
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q37.1	2	233205887	INPP5D	INPP5D, INPP5D	NA	NA	ENSG00000281614, ENSG00000168918	NA	NA	rs56235204-C	rs56235204	0	56235204	intron_variant	FALSE	0.1904	2e-14	13.698970004336019	NA	0.03490725	[0.026-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.1904	NA	0.03490725
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2p23.2	2	28463094	PLB1	PLB1	NA	NA	ENSG00000163803	NA	NA	rs11127153-A	rs11127153	0	11127153	intron_variant	FALSE	0.4899	2e-10	9.698970004336019	NA	0.0231478	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.4899	NA	0.0231478
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q37.3	2	241355498	FARP2, AC005104.3	SEPTIN2 - FARP2	ENSG00000168385	ENSG00000006607	NA	1471	787	rs3755397-G	rs3755397	0	3755397	regulatory_region_variant	TRUE	0.0977	2e-15	14.698970004336019	NA	0.04777988	[0.036-0.06] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0977	NA	0.04777988
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q37.3	2	241759225	D2HGDH	D2HGDH	NA	NA	ENSG00000180902	NA	NA	rs34290285-A	rs34290285	0	34290285	intron_variant	FALSE	0.2571	5e-24	23.30102999566398	NA	0.04123634	[0.033-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.2571	NA	0.04123634
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2p25.1	2	8299499	LINC00299	LINC00299	NA	NA	ENSG00000236790	NA	NA	rs10165200-A	rs10165200	0	10165200	intron_variant	FALSE	0.3712	7e-16	15.154901959985743	NA	0.02972809	[0.023-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.3712	NA	0.02972809
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2p15	2	61541105	XPO1	XPO1 - RPS29P10	ENSG00000082898	ENSG00000226884	NA	2364	48393	rs10542411-A	rs10542411	0	10542411	intergenic_variant	TRUE	0.5907	3e-10	9.522878745280337	NA	0.02302626	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.5907	NA	0.02302626
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2p11.2	2	85573959	VAMP8	VAMP8	NA	NA	ENSG00000118640	NA	NA	rs13007211-T	rs13007211	0	13007211	intron_variant	FALSE	0.3092	4e-9	8.397940008672037	NA	0.02323838	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.3092	NA	0.02323838
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q11.2	2	96535945	RP11-363D14.1, ARID5A	NEURL3 - ARID5A	ENSG00000163121	ENSG00000196843	NA	27836	798	rs2579500-A	rs2579500	0	2579500	intergenic_variant	TRUE	0.3889	8e-39	38.096910013008056	NA	0.04756093	[0.04-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.3889	NA	0.04756093
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q11.2	2	96570916	intergenic	ARID5A - KANSL3	ENSG00000196843	ENSG00000114982	NA	18282	22254	rs36058533-A	rs36058533	0	36058533	intergenic_variant	TRUE	0.3732	2e-37	36.69897000433602	NA	0.04736439	[0.04-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.3732	NA	0.04736439
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q12.1	2	102352408	IL18R1	IL18R1	NA	NA	ENSG00000115604	NA	NA	rs5833013-TTA	rs5833013	0	5833013	intron_variant	FALSE	0.3348	6e-93	92.22184874961636	NA	0.07943911	[0.072-0.087] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.3348	NA	0.07943911
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q12.1	2	102435015	AC007278.2	IL18RAP	NA	NA	ENSG00000115607	NA	NA	rs34020101-T	rs34020101	0	34020101	non_coding_transcript_exon_variant	FALSE	0.5999	5e-32	31.30102999566398	NA	0.04290931	[0.036-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.5999	NA	0.04290931
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	2q13	2	111142983	BCL2L11	MIR4435-2HG, BCL2L11	NA	NA	ENSG00000172965, ENSG00000153094	NA	NA	rs17484848-C	rs17484848	0	17484848	intron_variant	FALSE	0.1031	1e-26	26	NA	0.06296522	[0.051-0.075] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.1031	NA	0.06296522
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	20q11.21	20	31574549	HM13-AS1	HM13	NA	NA	ENSG00000101294	NA	NA	rs150929054-T	rs150929054	0	150929054	intron_variant	FALSE	0.0211	5e-9	8.301029995663981	NA	0.07456701	[0.05-0.1] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0211	NA	0.07456701
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	21q22.12	21	34911514	RUNX1	RUNX1	NA	NA	ENSG00000159216	NA	NA	rs28567906-G	rs28567906	0	28567906	intron_variant	FALSE	0.0883	3e-12	11.522878745280337	NA	0.04462155	[0.032-0.057] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0883	NA	0.04462155
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	21q22.12	21	35026289	RUNX1	RUNX1	NA	NA	ENSG00000159216	NA	NA	rs56117721-A	rs56117721	0	56117721	intron_variant	FALSE	0.0726	2e-56	55.69897000433602	NA	0.1094342	[0.096-0.123] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0726	NA	0.1094342
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	4q22.1	4	89704960	GPRIN3, SNCA	SNCA	NA	NA	ENSG00000145335	NA	NA	rs356182-?	rs356182	0	356182	intron_variant	FALSE	NR	1e-56	56	NA	1.318	[1.274-1.363]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.318	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	12q12	12	40259708	LRRK2	LRRK2	NA	NA	ENSG00000188906	NA	NA	rs28903073-?	rs28903073	0	28903073	intron_variant	FALSE	NR	1e-39	39	NA	3.1152647	[2.68-3.62]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	3.1152647	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	17q21.31	17	45628235	CRHR1, LRRC37A3	LINC02210, LINC02210, LINC02210-CRHR1, LINC02210-CRHR1	NA	NA	ENSG00000282171, ENSG00000204650, ENSG00000263715, ENSG00000282456	NA	NA	rs365825-?	rs365825	0	365825	intron_variant	FALSE	NR	4e-32	31.397940008672037	NA	1.2722646	[1.22-1.33]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.2722646	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	12p11.21	12	33148871	PKP2, SYT10	NA	NA	NA	NA	NA	NA	rs144847051-?	rs144847051	0	144847051	intergenic_variant	TRUE	NR	4e-21	20.397940008672037	NA	2.2371366	[1.92-2.61]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	2.2371366	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	6p21.32	6	32604184	HLA-DQA1, HLA-DRB5	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735	NA	14336	23995	rs17425622-?	rs17425622	0	17425622	intron_variant	TRUE	NR	4e-17	16.397940008672037	NA	1.235	[1.174-1.298]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.235	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	1q22	1	155236376	GBA	GBA, GBA	NA	NA	ENSG00000262446, ENSG00000177628	NA	NA	rs2230288-?	rs2230288	0	2230288	missense_variant	FALSE	NR	5e-17	16.30102999566398	NA	1.674	[1.495-1.873]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.674	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	2q24.3	2	168299085	STK39, CERS6	STK39 - NA	ENSG00000198648	NA	NA	51490	NA	rs13016703-?	rs13016703	0	13016703	intergenic_variant	TRUE	NR	3e-16	15.522878745280337	NA	1.2091899	[1.16-1.26]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.2091899	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	4p16.3	4	879499	GAK	GAK	NA	NA	ENSG00000178950	NA	NA	rs35541465-?	rs35541465	0	35541465	intron_variant	FALSE	NR	3e-15	14.522878745280337	NA	1.1560693	[1.12-1.20]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.1560693	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	14q22.2	14	54882151	GCH1	GCH1	NA	NA	ENSG00000131979	NA	NA	rs11158026-?	rs11158026	0	11158026	intron_variant	FALSE	NR	9e-15	14.045757490560675	NA	1.1454753	[1.11-1.18]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.1454753	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	3q27.1	3	183012503	DCUN1D1, MCCC1	DCUN1D1 - MCCC1	ENSG00000043093	ENSG00000078070	NA	26550	2715	rs9858038-?	rs9858038	0	9858038	intergenic_variant	TRUE	NR	3e-14	13.522878745280337	NA	1.172	[1.124-1.221]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.172	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	7p15.3	7	23084258	FAM126A, KLHL7	FAM126A - KLHL7-DT	ENSG00000122591	ENSG00000230658	NA	70128	15956	rs10256359-?	rs10256359	0	10256359	intergenic_variant	TRUE	NR	2e-12	11.698970004336019	NA	1.1273957	[1.09-1.17]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.1273957	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	1q32.1	1	205754444	RAB7L1, NUCKS1	NUCKS1 - RAB29	ENSG00000069275	ENSG00000117280	NA	4262	13542	rs823118-?	rs823118	0	823118	intergenic_variant	TRUE	NR	6e-12	11.221848749616356	NA	1.117	[1.082-1.153]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.117	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	10q26.11	10	119612816	TIAL1, BAG3	TIAL1 - RAD1P1	ENSG00000151923	ENSG00000234569	NA	15787	8252	rs188789342-?	rs188789342	0	188789342	intergenic_variant	TRUE	NR	3e-11	10.522878745280337	NA	1.488	[1.331-1.663]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.488	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	4q21.1	4	76277833	FAM47E	FAM47E-STBD1, FAM47E	NA	NA	ENSG00000272414, ENSG00000189157	NA	NA	rs6812193-?	rs6812193	0	6812193	intron_variant	FALSE	NR	7e-11	10.154901959985743	NA	1.1148272	[1.08-1.15]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.1148272	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	4p15.32	4	15735495	BST1, CD38	BST1	NA	NA	ENSG00000109743	NA	NA	rs4266290-?	rs4266290	0	4266290	intron_variant	FALSE	NR	8e-11	10.096910013008056	NA	1.128	[1.088-1.171]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.128	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	18q12.3	18	43098270	RIT2	RIT2	NA	NA	ENSG00000152214	NA	NA	rs4130047-?	rs4130047	0	4130047	intron_variant	FALSE	NR	2e-10	9.698970004336019	NA	1.1148272	[1.08-1.15]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.1148272	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	6p22.1	6	27709015	ZNF184, HIST1H2BL	LINC01012	NA	NA	ENSG00000281706	NA	NA	rs4713118-?	rs4713118	0	4713118	non_coding_transcript_exon_variant	FALSE	NR	2e-10	9.698970004336019	NA	1.121	[1.083-1.162]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.121	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	12q24.31	12	122819039	CCDC62	CCDC62	NA	NA	ENSG00000130783	NA	NA	rs11060180-?	rs11060180	0	11060180	intron_variant	FALSE	NR	3e-10	9.522878745280337	NA	1.1074197	[1.07-1.14]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.1074197	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	11q12.1	11	57926788	CTNND1, OR9Q1	OR5AZ1P - OR5BD1P	ENSG00000180714	ENSG00000254749	NA	8549	18810	rs687432-?	rs687432	0	687432	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	NA	1.113	[1.075-1.153]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.113	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	12q12	12	42655580	PRICKLE1, ADAMTS20	LINC02451	NA	NA	ENSG00000257164	NA	NA	rs148294058-?	rs148294058	0	148294058	intron_variant	FALSE	NR	5e-9	8.301029995663981	NA	1.5698587	[1.36-1.81]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.5698587	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	9p22.2	9	17736344	SH3GL2	SH3GL2	NA	NA	ENSG00000107295	NA	NA	rs2209440-?	rs2209440	0	2209440	intron_variant	FALSE	NR	8e-9	8.096910013008056	NA	1.0964912	[1.06-1.13]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.0964912	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	16p12.3	16	19268142	SYT17, CLEC19A	SYT17	NA	NA	ENSG00000103528	NA	NA	rs11343-?	rs11343	0	11343	3_prime_UTR_variant	FALSE	NR	1e-8	8	NA	1.096	[1.062-1.131]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.096	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	5q12.1	5	60964716	NDUFAF2	NDUFAF2	NA	NA	ENSG00000164182	NA	NA	rs162227-?	rs162227	0	162227	intron_variant	FALSE	NR	1e-8	8	NA	1.1627907	[1.10-1.22]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.1627907	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	8q12.1	8	60251336	CA8	CA8	NA	NA	ENSG00000178538	NA	NA	rs144074972-?	rs144074972	0	144074972	intron_variant	FALSE	NR	6e-8	7.221848749616356	NA	NA	NA	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Parkinson's disease	9,619 European ancestry cases, 324,522 European ancestry controls	NA	17q21.2	17	42546140	HSD17B1, GLU	NAGLU - HSD17B1P1	ENSG00000108784	ENSG00000108785	NA	1691	624	rs601999-?	rs601999	0	601999	intron_variant	TRUE	NR	7e-8	7.154901959985743	NA	1.095	[1.060-1.132]	Illumina [12438219] (imputed)	N	Parkinson's disease	http://www.ebi.ac.uk/efo/EFO_0002508	GCST003984	Genome-wide genotyping array	NA	1.095	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7q31.32	7	123677086	WASL	LMOD2 - WASL	ENSG00000170807	ENSG00000106299	NA	12796	4857	rs1506636-G	rs1506636	0	1506636	intergenic_variant	TRUE	0.6784	7e-11	10.154901959985743	NA	0.02551785	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6784	NA	0.02551785
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7q31.32	7	123784655	intergenic	WASL-DT - RNU6-11P	ENSG00000272686	ENSG00000201104	NA	33489	5950	rs725860-C	rs725860	0	725860	regulatory_region_variant	TRUE	0.08	9e-19	18.045757490560675	NA	0.0597362	[0.047-0.073] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.08	NA	0.0597362
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7q32.2	7	129663533	NRF1	NRF1	NA	NA	ENSG00000106459	NA	NA	rs7789516-C	rs7789516	0	7789516	intron_variant	FALSE	0.9022	6e-9	8.221848749616356	NA	0.0359149	[0.024-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.9022	NA	0.0359149
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7q32.2	7	130023656	ZC3HC1	ZC3HC1	NA	NA	ENSG00000091732	NA	NA	rs11556924-T	rs11556924	0	11556924	missense_variant	FALSE	0.3885	4e-9	8.397940008672037	NA	0.02204853	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3885	NA	0.02204853
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7q32.3	7	131073817	LINC-PINT	LINC-PINT	NA	NA	ENSG00000231721	NA	NA	rs12669378-T	rs12669378	0	12669378	intron_variant	FALSE	0.7355	3e-13	12.522878745280337	NA	0.03012393	[0.022-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7355	NA	0.03012393
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7q33	7	135661514	C7orf73	NUP205 - STMP1	ENSG00000155561	ENSG00000243317	NA	12757	982	rs35150201-G	rs35150201	0	35150201	regulatory_region_variant	TRUE	0.4835	3e-14	13.522878745280337	NA	0.0280558	[0.021-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4835	NA	0.0280558
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	NA	NA	NA	KDM7A	NA	NA	NA	NA	NA	NA	chr7:139843525-T	chr7:139843525	0	NA	NA	TRUE	0.0999	1e-9	9	NA	0.03697063	[0.025-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0999	NA	0.03697063
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	8p12	8	30423317	RBPMS	RBPMS	NA	NA	ENSG00000157110	NA	NA	rs2979489-A	rs2979489	0	2979489	intron_variant	FALSE	0.7422	5e-14	13.301029995663981	NA	0.03141117	[0.023-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7422	NA	0.03141117
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	8q13.1	8	65909795	intergenic	PDE7A-DT - NA	ENSG00000272192	NA	NA	66464	NA	rs6472235-G	rs6472235	0	6472235	intergenic_variant	TRUE	0.3457	6e-12	11.221848749616356	NA	0.02646344	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3457	NA	0.02646344
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	8q23.1	8	105569300	ZFPM2	ZFPM2-AS1, ZFPM2	NA	NA	ENSG00000251003, ENSG00000169946	NA	NA	rs6993770-T	rs6993770	0	6993770	intron_variant	FALSE	0.2854	7e-40	39.15490195998574	NA	0.05340481	[0.045-0.061] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2854	NA	0.05340481
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	8q24.21	8	127816127	PVT1	PVT1	NA	NA	ENSG00000249859	NA	NA	rs10622381-CACAA	rs10622381	0	10622381	intron_variant	FALSE	0.5675	8e-9	8.096910013008056	NA	0.02171582	[0.014-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5675	NA	0.02171582
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	8q24.3	8	141291925	SLC45A4, RP11-10J21.5	SLC45A4	NA	NA	ENSG00000022567	NA	NA	rs12677618-T	rs12677618	0	12677618	intron_variant	FALSE	0.2611	3e-11	10.522878745280337	NA	0.02776526	[0.02-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2611	NA	0.02776526
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	NA	NA	NA	PLEC	NA	NA	NA	NA	NA	NA	chr8:145001784-G	chr8:145001784	0	NA	NA	TRUE	0.4239	2e-18	17.69897000433602	NA	0.032434	[0.025-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4239	NA	0.032434
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9p24.1	9	4763368	intergenic	AK3 - ECM1P1	ENSG00000147853	ENSG00000270639	NA	21325	5249	rs409950-A	rs409950	0	409950	intergenic_variant	TRUE	0.1815	4e-49	48.39794000867204	NA	0.0729848	[0.063-0.083] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1815	NA	0.0729848
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9p24.1	9	4763491	intergenic	AK3 - ECM1P1	ENSG00000147853	ENSG00000270639	NA	21448	5126	rs12005199-A	rs12005199	0	12005199	intergenic_variant	TRUE	0.3081	4e-213	212.39794000867204	NA	0.1291029	[0.12-0.14] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3081	NA	0.1291029
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9p24.1	9	4840380	RCL1	RCL1	NA	NA	ENSG00000120158	NA	NA	rs10974808-G	rs10974808	0	10974808	intron_variant	FALSE	0.145	7e-151	150.15490195998575	NA	0.1356046	[0.13-0.15] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.145	NA	0.1356046
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9p24.1	9	4856234	RCL1	RCL1	NA	NA	ENSG00000120158	NA	NA	rs1887430-A	rs1887430	0	1887430	intron_variant	FALSE	0.5907	9e-99	98.04575749056067	NA	0.07844472	[0.071-0.086] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5907	NA	0.07844472
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9p24.1	9	5015901	JAK2	JAK2	NA	NA	ENSG00000096968	NA	NA	rs10815146-A	rs10815146	0	10815146	intron_variant	FALSE	0.5055	2e-30	29.69897000433602	NA	0.04194053	[0.035-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5055	NA	0.04194053
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9p24.1	9	5081828	JAK2	JAK2	NA	NA	ENSG00000096968	NA	NA	rs150221602-C	rs150221602	0	150221602	missense_variant	FALSE	0.0014	1e-13	13	NA	0.4091	[0.3-0.52] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0014	NA	0.4091
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9p24.1	9	5126343	JAK2	JAK2, INSL6	NA	NA	ENSG00000096968, ENSG00000120210	NA	NA	rs41316003-A	rs41316003	0	41316003	missense_variant	FALSE	0.005	8e-10	9.096910013008056	NA	0.170913	[0.12-0.23] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.005	NA	0.170913
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9p21.3	9	21986848	CDKN2A, RP11-145E5.5	CDKN2A	NA	NA	ENSG00000147889	NA	NA	rs3731211-A	rs3731211	0	3731211	intron_variant	FALSE	0.7212	6e-29	28.221848749616356	NA	0.04550482	[0.038-0.053] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7212	NA	0.04550482
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9p21.3	9	22151140	intergenic	CDKN2B-AS1 - DMRTA1	ENSG00000240498	ENSG00000176399	NA	23037	295684	rs6475611-A	rs6475611	0	6475611	intergenic_variant	TRUE	0.1619	1e-36	36	NA	0.06329283	[0.053-0.073] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1619	NA	0.06329283
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9p13.1	9	38198232	intergenic	U8 - FANCC	ENSG00000212594	ENSG00000158169	NA	50671	56900822	rs11446839-TG	rs11446839	0	11446839	intergenic_variant	TRUE	0.4867	3e-16	15.522878745280337	NA	0.02990532	[0.023-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4867	NA	0.02990532
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9q22.1	9	88777772	intergenic	MIR4289 - PCNPP2	ENSG00000265873	ENSG00000225856	NA	31867	193115	rs142550358-T	rs142550358	0	142550358	intron_variant	TRUE	0.0546	1e-38	38	NA	0.1064998	[0.09-0.123] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0546	NA	0.1064998
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9q22.32	9	96430637	intergenic	ZNF367 - HABP4	ENSG00000165244	ENSG00000130956	NA	12267	19532	rs10820606-C	rs10820606	0	10820606	intergenic_variant	TRUE	0.2334	1e-21	21	NA	0.04198657	[0.033-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2334	NA	0.04198657
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	12q22	12	95633983	USP44, NTN4	PGAM1P5	NA	NA	ENSG00000257150	NA	NA	rs17356907-?	rs17356907	0	17356907	intron_variant	FALSE	NR	1e-13	13	NA	0.097	[0.071-0.123] unit increase	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.097
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	4q13.3	4	74621799	AREG, BTC	NA	NA	NA	NA	NA	NA	rs7659874-?	rs7659874	0	7659874	intergenic_variant	TRUE	NR	9e-13	12.045757490560675	NA	0.105	[0.134-0.076] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.105
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	8p11.23	8	36989597	KCNU1, ZNF703	KCNU1 - NA	ENSG00000215262	NA	NA	53472	NA	rs10110651-?	rs10110651	0	10110651	intergenic_variant	TRUE	NR	7e-31	30.154901959985743	NA	0.177	[0.147-0.207] unit increase	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.177
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	2q14.2	2	120332155	INHBB, RALB	RALB - INHBB	ENSG00000144118	ENSG00000163083	NA	37445	13981	rs17625845-?	rs17625845	0	17625845	intergenic_variant	TRUE	NR	6e-18	17.221848749616356	NA	0.14	[0.171-0.108] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.14
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	10q21.2	10	62418899	ZNF365	ZNF365	NA	NA	ENSG00000138311	NA	NA	rs3081227-?	rs3081227	0	3081227	intron_variant	FALSE	NR	3e-15	14.522878745280337	NA	0.103	[0.129-0.078] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.103
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	12p11.22	12	28001962	PTHLH, CCDC91	PTHLH - NA	ENSG00000087494	NA	NA	29229	NA	rs1838564-?	rs1838564	0	1838564	intergenic_variant	TRUE	NR	1e-12	12	NA	0.136	[0.099-0.174] unit increase	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.136
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	22q13.1	22	40564688	MKL1	MRTFA	NA	NA	ENSG00000196588	NA	NA	rs5995875-?	rs5995875	0	5995875	intron_variant	FALSE	NR	3e-12	11.522878745280337	NA	0.137	[0.176-0.099] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.137
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	6q25.1	6	151631197	CCDC170, ESR1	CCDC170 - ESR1	ENSG00000120262	ENSG00000091831	NA	10004	25494	rs9397437-?	rs9397437	0	9397437	regulatory_region_variant	TRUE	NR	1e-11	11	NA	0.158	[0.204-0.112] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.158
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	11q13.3	11	69328516	MYEOV, CCND1	MYEOV	NA	NA	ENSG00000172927	NA	NA	rs7102705-?	rs7102705	0	7102705	intron_variant	FALSE	NR	1e-9	9	NA	0.089	[0.118-0.061] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.089
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	1p12	1	118227648	SPAG17, TBX15	SPAG17 - RNA5SP56	ENSG00000155761	ENSG00000222209	NA	42420	36724	rs2359714-?	rs2359714	0	2359714	intergenic_variant	TRUE	NR	4e-9	8.397940008672037	NA	0.071	[0.047-0.095] unit increase	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.071
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	2p25.3	2	632922	FAM150B, TMEM18	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	86255	30955	rs62105303-?	rs62105303	0	62105303	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	NA	0.086	[0.117-0.056] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.086
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	1q32.1	1	201917642	LMOD1	LMOD1	NA	NA	ENSG00000163431	NA	NA	rs34091558-?	rs34091558	0	34091558	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	0.072	[0.098-0.047] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.072
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	1p12	1	118957860	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs2645288-?	rs2645288	0	2645288	intron_variant	FALSE	NR	1e-7	7	NA	0.077	[0.105-0.049] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.077
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	1q23.2	1	160269067	DCAF8, COPA	RPSAP18 - PEX19	ENSG00000224261	ENSG00000162735	NA	1842	7740	rs6427508-?	rs6427508	0	6427508	intron_variant	TRUE	NR	1e-7	7	NA	0.067	[0.092-0.042] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.067
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	12q13.12	12	49868026	FAIM2	FAIM2	NA	NA	ENSG00000135472	NA	NA	rs3205718-?	rs3205718	0	3205718	3_prime_UTR_variant	FALSE	NR	1e-7	7	NA	0.067	[0.042-0.092] unit increase	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.067
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	15q22.2	15	61928573	VPS13C	VPS13C	NA	NA	ENSG00000129003	NA	NA	rs148713408-?	rs148713408	0	148713408	intron_variant	FALSE	NR	2e-7	6.698970004336019	NA	0.339	[0.212-0.466] unit increase	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.339
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	1p36.22	1	10506215	PEX14	PEX14	NA	NA	ENSG00000142655	NA	NA	rs616402-?	rs616402	0	616402	intron_variant	FALSE	NR	2e-7	6.698970004336019	NA	0.067	[0.093-0.042] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.067
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	16q12.2	16	53790314	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs62033406-?	rs62033406	0	62033406	intron_variant	FALSE	NR	4e-7	6.3979400086720375	NA	0.062	[0.038-0.087] unit increase	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.062
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	14q32.13	14	94378610	SERPINA1	SERPINA1, SERPINA1	NA	NA	ENSG00000197249, ENSG00000277377	NA	NA	rs28929474-?	rs28929474	0	28929474	missense_variant	FALSE	NR	5e-7	6.301029995663981	NA	0.215	[0.299-0.131] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.215
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	22q12.1	22	28764326	HSCB, CCDC117	HSCB - CCDC117	ENSG00000100209	ENSG00000159873	NA	6811	8348	rs5752793-?	rs5752793	0	5752793	intergenic_variant	TRUE	NR	7e-7	6.154901959985743	NA	0.065	[0.039-0.090] unit increase	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.065
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	1q41	1	220527824	RAB3GAP2, MARK1	LINC02779 - MARK1	ENSG00000231529	ENSG00000116141	NA	40266	312	rs200550907-?	rs200550907	0	200550907	regulatory_region_variant	TRUE	NR	8e-7	6.096910013008056	NA	0.077	[0.107-0.046] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.077
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	8p12	8	30384102	DCTN6, RBPMS	RBPMS-AS1	NA	NA	ENSG00000254109	NA	NA	rs113198678-?	rs113198678	0	113198678	intron_variant	FALSE	NR	1e-6	6	NA	0.12	[0.169-0.072] unit decrease	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	0.12
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Breast size	33,790 European ancestry individuals	NA	3p14.2	3	62747691	CADPS	CADPS	NA	NA	ENSG00000163618	NA	NA	rs580384-?	rs580384	0	580384	intron_variant	FALSE	NR	2e-6	5.698970004336019	NA	NA	NA	Illumina [12039487] (imputed)	N	breast size	http://www.ebi.ac.uk/efo/EFO_0004884	GCST003985	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	12q13.3	12	57133500	LRP1	LRP1	NA	NA	ENSG00000123384	NA	NA	rs11172113-?	rs11172113	0	11172113	intron_variant	FALSE	NR	6e-36	35.221848749616356	NA	1.102	[1.086-1.120]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.102	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	1p36.32	1	3164677	PRDM16	PRDM16	NA	NA	ENSG00000142611	NA	NA	rs2075968-?	rs2075968	0	2075968	intron_variant	FALSE	NR	9e-28	27.045757490560675	NA	1.102	[1.083-1.122]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.102	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q12	4	53933078	LNX1-AS2, RPL21P44	LNX1 - RPL21P44	ENSG00000072201	ENSG00000229585	NA	231673	53509	rs871606-T	rs871606	0	871606	intron_variant	TRUE	NA	1e-12	12	NA	0.262	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p36.22	1	10736809	CASZ1	CASZ1	NA	NA	ENSG00000130940	NA	NA	rs880315-T	rs880315	0	880315	intron_variant	FALSE	NA	2e-12	11.698970004336019	NA	0.185	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q31.21	4	143266227	USP38, GAB1	USP38 - Y_RNA	ENSG00000170185	ENSG00000199964	NA	42353	43239	rs893929-G	rs893929	0	893929	intergenic_variant	TRUE	NA	1e-7	7	NA	0.124	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q27	6	165761983	PDE10A, LINC00473	PDE10A	NA	NA	ENSG00000112541	NA	NA	rs903432-A	rs903432	0	903432	intron_variant	FALSE	NA	5e-12	11.301029995663981	NA	0.313	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q23.33	10	94136183	PLCE1	PLCE1	NA	NA	ENSG00000138193	NA	NA	rs932764-A	rs932764	0	932764	intron_variant	FALSE	NA	1e-7	7	NA	0.125	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q15.1	15	40029923	EIF2AK4	EIF2AK4	NA	NA	ENSG00000128829	NA	NA	rs937213-T	rs937213	0	937213	intron_variant	FALSE	NA	8e-8	7.096910013008056	NA	0.131	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q32	5	149011577	SH3TC2	SH3TC2	NA	NA	ENSG00000169247	NA	NA	rs9687065-A	rs9687065	0	9687065	intron_variant	FALSE	NA	7e-19	18.154901959985743	NA	0.262	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p22.1	3	41871159	ULK4	ULK4	NA	NA	ENSG00000168038	NA	NA	rs9815354-G	rs9815354	0	9815354	intron_variant	FALSE	NA	1e-26	26	NA	0.333	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p14.3	3	56667300	FAM208A	TASOR	NA	NA	ENSG00000163946	NA	NA	rs9845655-T	rs9845655	0	9845655	intron_variant	FALSE	NA	5e-10	9.301029995663981	NA	0.161	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q22.3	3	138392909	MRAS	MRAS	NA	NA	ENSG00000158186	NA	NA	rs9864898-C	rs9864898	0	9864898	intron_variant	FALSE	NA	5e-9	8.301029995663981	NA	0.19	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q21.1	3	122391302	FAM162A	FAM162A	NA	NA	ENSG00000114023	NA	NA	rs9882772-T	rs9882772	0	9882772	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.133	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16p12.3	16	21079970	DNAH3	DNAH3	NA	NA	ENSG00000158486	NA	NA	rs9935770-C	rs9935770	0	9935770	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	0.111	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.5	11	1884062	LSP1	LSP1	NA	NA	ENSG00000130592	NA	NA	rs661348-T	rs661348	0	661348	intron_variant	FALSE	NA	9e-9	8.045757490560675	NA	0.173	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.4	11	10004305	NR	SBF2	NA	NA	ENSG00000133812	NA	NA	rs66803065-C	rs66803065	0	66803065	intron_variant	FALSE	NA	5e-11	10.301029995663981	NA	0.209	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6p12.1	6	54112697	MLIP	MLIP	NA	NA	ENSG00000146147	NA	NA	rs670463-A	rs670463	0	670463	intron_variant	FALSE	NA	2e-9	8.698970004336019	NA	0.158	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q11.2	2	100962027	NPAS2	NPAS2	NA	NA	ENSG00000170485	NA	NA	rs6747874-G	rs6747874	0	6747874	intron_variant	FALSE	NA	1e-8	8	NA	0.171	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q23	3	141909018	ATP1B3	ATP1B3	NA	NA	ENSG00000069849	NA	NA	rs6782694-C	rs6782694	0	6782694	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.19	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p25.1	3	13781845	LINC00620, WNT7A	LINC00620 - WNT7A	ENSG00000224514	ENSG00000154764	NA	35207	34413	rs6793656-A	rs6793656	0	6793656	intergenic_variant	TRUE	NA	6e-10	9.221848749616356	NA	0.224	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p21.31	3	48156124	MAP4, CDC25A	RN7SL664P - CDC25A	ENSG00000265078	ENSG00000164045	NA	61019	1022	rs6797587-A	rs6797587	0	6797587	regulatory_region_variant	TRUE	NA	3e-6	5.522878745280337	NA	0.126	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p12.1	3	84936937	LOC440970, MIR5688	LINC02025 - CADM2	ENSG00000242339	ENSG00000175161	NA	43558	22052	rs6803322-C	rs6803322	0	6803322	intergenic_variant	TRUE	NA	3e-6	5.522878745280337	NA	0.13	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q12.1	11	57889941	CTNND1, OR6Q1	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	NA	16353	27356	rs685149-A	rs685149	0	685149	intergenic_variant	TRUE	NA	1e-11	11	NA	0.186	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	9p13.1	9	38088247	SHB, ALDH1B1	SHB - U8	ENSG00000107338	ENSG00000212594	NA	19020	59181	rs7019055-A	rs7019055	0	7019055	regulatory_region_variant	TRUE	NA	7e-9	8.154901959985743	NA	0.15	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	9p24.1	9	8010674	C9orf123, PTPRD	NA	NA	NA	NA	NA	NA	rs7041664-C	rs7041664	0	7041664	intergenic_variant	TRUE	NA	6e-9	8.221848749616356	NA	0.166	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p11.2	11	47654618	MTCH2, AGBL2	MTCH2 - AGBL2	ENSG00000109919	ENSG00000165923	NA	12011	4973	rs7107356-A	rs7107356	0	7107356	intergenic_variant	TRUE	NA	3e-10	9.522878745280337	NA	0.159	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.4	11	10328991	ADM, AMPD3	AMPD3	NA	NA	ENSG00000133805	NA	NA	rs7129220-G	rs7129220	0	7129220	intron_variant	FALSE	NA	6e-13	12.221848749616356	NA	0.296	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	14q22.1	14	52899431	FERMT2	FERMT2	NA	NA	ENSG00000073712	NA	NA	rs7161323-C	rs7161323	0	7161323	non_coding_transcript_exon_variant	FALSE	NA	2e-6	5.698970004336019	NA	0.132	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17q23.3	17	64330199	PECAM1, MILR1	PECAM1	NA	NA	ENSG00000261371	NA	NA	rs7225219-T	rs7225219	0	7225219	intron_variant	FALSE	NA	8e-7	6.096910013008056	NA	0.137	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17p13.1	17	6570508	PITPNM3, KIAA0753	PITPNM3 - KIAA0753	ENSG00000091622	ENSG00000198920	NA	13953	7639	rs7226020-T	rs7226020	0	7226020	regulatory_region_variant	TRUE	NA	2e-17	16.69897000433602	NA	0.232	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p24.1	2	20679060	GDF7, C2orf43	GDF7	NA	NA	ENSG00000143869	NA	NA	rs7255-T	rs7255	0	7255	3_prime_UTR_variant	FALSE	NA	2e-15	14.698970004336019	NA	0.205	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16p11.2	16	30925422	FBXL19	FBXL19	NA	NA	ENSG00000099364	NA	NA	rs72799341-G	rs72799341	0	72799341	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	0.132	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q35	2	216781800	IGFBP5, TNP1	IGFBP5 - RPL31P14	ENSG00000115461	ENSG00000237930	NA	86251	3974	rs72958213-C	rs72958213	0	72958213	intron_variant	TRUE	NA	5e-8	7.301029995663981	NA	0.177	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q13.13	12	54049306	HOXC4	HOXC4	NA	NA	ENSG00000198353	NA	NA	rs7297416-A	rs7297416	0	7297416	intron_variant	FALSE	NA	2e-10	9.698970004336019	NA	0.175	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q24.11	12	109914704	TCHP	TCHP	NA	NA	ENSG00000139437	NA	NA	rs7312132-G	rs7312132	0	7312132	non_coding_transcript_exon_variant	FALSE	NA	7e-9	8.154901959985743	NA	0.283	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q26.1	15	89021727	MFGE8, ABHD2	KRT18P47 - CARMAL	ENSG00000259489	ENSG00000260123	NA	60681	19496	rs734780-T	rs734780	0	734780	regulatory_region_variant	TRUE	NA	2e-8	7.698970004336019	NA	0.245	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10p12.31	10	20240541	PLXDC2	PLXDC2	NA	NA	ENSG00000120594	NA	NA	rs73605614-A	rs73605614	0	73605614	intron_variant	FALSE	NA	1e-8	8	NA	0.177	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	19p13.3	19	2232222	DOT1L	PLEKHJ1, DOT1L	NA	NA	ENSG00000104886, ENSG00000104885	NA	NA	rs740406-A	rs740406	0	740406	3_prime_UTR_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.326	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p11.2	11	44009233	C11orf96, ACCSL	C11orf96 - ACCSL	ENSG00000187479	ENSG00000205126	NA	65355	38748	rs74482535-C	rs74482535	0	74482535	intergenic_variant	TRUE	NA	1e-9	9	NA	0.271	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p25.3	3	8454685	LOC100288428	LMCD1-AS1	NA	NA	ENSG00000227110	NA	NA	rs74621754-G	rs74621754	0	74621754	intron_variant	FALSE	NA	3e-8	7.522878745280337	NA	0.36	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.5	11	1899025	NR	LINC01150	NA	NA	ENSG00000229671	NA	NA	rs7483477-T	rs7483477	0	7483477	intron_variant	FALSE	NA	1e-13	13	NA	0.219	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16q23.3	16	83012185	CDH13	CDH13	NA	NA	ENSG00000140945	NA	NA	rs7500448-A	rs7500448	0	7500448	intron_variant	FALSE	NA	3e-24	23.522878745280337	NA	0.301	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1q24.2	1	169238123	NME7	NME7	NA	NA	ENSG00000143156	NA	NA	rs7519279-G	rs7519279	0	7519279	intron_variant	FALSE	NA	1e-13	13	NA	0.21	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17q21.32	17	46890164	NR	WNT9B - LINC01974	ENSG00000276799	ENSG00000262031	NA	3434	19578	rs75230966-G	rs75230966	0	75230966	regulatory_region_variant	TRUE	NA	2e-32	31.69897000433602	NA	0.47	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.1	11	17330136	NUCB2	NUCB2	NA	NA	ENSG00000070081	NA	NA	rs757081-C	rs757081	0	757081	missense_variant	FALSE	NA	8e-8	7.096910013008056	NA	0.146	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p16.1	2	59107969	FLJ30838, MIR4432	LINC01122 - NA	ENSG00000233723	NA	NA	44203	NA	rs7575523-T	rs7575523	0	7575523	intron_variant	TRUE	NA	5e-8	7.301029995663981	NA	0.142	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p25.1	2	9159963	MBOAT2, ASAP2	RPL30P3 - ASAP2	ENSG00000223640	ENSG00000151693	NA	78236	46802	rs7586597-G	rs7586597	0	7586597	intergenic_variant	TRUE	NA	7e-9	8.154901959985743	NA	0.154	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p13.2	2	71302201	PAIP2B, ZNF638	ZNF638	NA	NA	ENSG00000075292	NA	NA	rs7605066-C	rs7605066	0	7605066	intron_variant	FALSE	NA	6e-9	8.221848749616356	NA	0.149	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q31.21	4	145893488	ZNF827	ZNF827	NA	NA	ENSG00000151612	NA	NA	rs7666150-T	rs7666150	0	7666150	intron_variant	FALSE	NA	6e-9	8.221848749616356	NA	0.15	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q22	12	94489129	LOC144486, MIR5700	CEP83-DT - RN7SL483P	ENSG00000278916	ENSG00000244091	NA	26645	26347	rs76785029-C	rs76785029	0	76785029	regulatory_region_variant	TRUE	NA	5e-14	13.301029995663981	NA	0.379	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q13.2	5	72359028	PTCD2	PTCD2	NA	NA	ENSG00000049883	NA	NA	rs7714219-G	rs7714219	0	7714219	3_prime_UTR_variant	FALSE	NA	4e-9	8.397940008672037	NA	0.164	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p34.2	1	41902364	HIVEP3	HIVEP3	NA	NA	ENSG00000127124	NA	NA	rs783621-A	rs783621	0	783621	intron_variant	FALSE	NA	3e-16	15.522878745280337	NA	0.207	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2017-06-20	28274756	Mhatre S	2017-03-03	Lancet Oncol	www.ncbi.nlm.nih.gov/pubmed/28274756	Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.	Gallbladder cancer	1,042 Indian ancestry cases, 1,709 Indian ancestry controls	428 Indian ancestry cases, 420 Indian ancestry controls	7q21.12	7	87449753	ABCB4	ABCB4	NA	NA	ENSG00000005471	NA	NA	rs1558375-A	rs1558375	0	1558375	intron_variant	FALSE	0.74	2e-10	9.698970004336019	NA	1.47	[1.30-1.66]	Illumina [10400000] (imputed)	N	gallbladder neoplasm	http://www.ebi.ac.uk/efo/EFO_0004606	GCST004201	Genome-wide genotyping array	0.74	1.47	NA
2017-06-20	28274756	Mhatre S	2017-03-03	Lancet Oncol	www.ncbi.nlm.nih.gov/pubmed/28274756	Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.	Gallbladder cancer	1,042 Indian ancestry cases, 1,709 Indian ancestry controls	428 Indian ancestry cases, 420 Indian ancestry controls	7q21.12	7	87495506	ABCB1	ABCB4 - ABCB1	ENSG00000005471	ENSG00000085563	NA	15071	7511	rs17209837-A	rs17209837	0	17209837	intergenic_variant	TRUE	0.85	2e-9	8.698970004336019	NA	1.61	[1.38-1.89]	Illumina [10400000] (imputed)	N	gallbladder neoplasm	http://www.ebi.ac.uk/efo/EFO_0004606	GCST004201	Genome-wide genotyping array	0.85	1.61	NA
2017-04-20	28012008	Lu S	2016-12-23	J Bone Miner Metab	www.ncbi.nlm.nih.gov/pubmed/28012008	Bivariate genome-wide association analyses identified genetic pleiotropic effects for bone mineral density and alcohol drinking in Caucasians.	Spine bone mineral density and alcohol drinking	506 European ancestry males, 1,553 European ancestry females	NA	11q22.3	11	103196731	DYNC2H1	DYNC2H1	NA	NA	ENSG00000187240	NA	NA	rs685395-?	rs685395	0	685395	intron_variant	FALSE	NR	2e-8	7.698970004336019	(males)	NA	NA	Affymetrix [69108]	N	alcohol consumption measurement, spine bone mineral density	http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0007701	GCST003919	Genome-wide genotyping array	NA	NA	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	16q24.3	16	89919709	MC1R	MC1R	NA	NA	ENSG00000258839	NA	NA	rs1805007-T	rs1805007	0	1805007	missense_variant	FALSE	0.07	4e-37	36.39794000867204	NA	1.5	[1.41-1.59]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.07	1.5	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	5p13.2	5	33946466	SLC45A2	SLC45A2, SLC45A2	NA	NA	ENSG00000164175, ENSG00000281919	NA	NA	rs35407-G	rs35407	0	35407	3_prime_UTR_variant	FALSE	0.97	3e-19	18.522878745280337	NA	2.0833335	[1.79-2.44]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.97	2.0833335	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	20q11.22	20	34077942	RALY, ASIP	RALY	NA	NA	ENSG00000125970	NA	NA	rs6059655-A	rs6059655	0	6059655	intron_variant	FALSE	0.07	5e-23	22.30102999566398	NA	1.38	[1.29-1.47]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.07	1.38	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	9p21.3	9	21805208	MTAP	MTAP	NA	NA	ENSG00000099810	NA	NA	rs201131773-?	rs201131773	0	201131773	intron_variant	FALSE	0.48	3e-17	16.522878745280337	NA	1.19	[1.15-1.24]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.48	1.19	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	6p25.3	6	421281	IRF4, EXOC2	IRF4 - EXOC2	ENSG00000137265	ENSG00000112685	NA	9838	63873	rs62389423-A	rs62389423	0	62389423	intergenic_variant	TRUE	0.14	9e-14	13.045757490560675	NA	1.24	[1.17-1.31]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.14	1.24	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	5p15.33	5	1284538	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs139996880-A	rs139996880	0	139996880	intron_variant	FALSE	0.16	7e-12	11.154901959985743	NA	1.26	[1.18-1.34]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.16	1.26	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	11q14.3	11	89277878	TYR	TYR	NA	NA	ENSG00000077498	NA	NA	rs1393350-A	rs1393350	0	1393350	intron_variant	FALSE	0.27	4e-13	12.397940008672037	NA	1.17	[1.12-1.22]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.27	1.17	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	21q22.3	21	41374154	MX2	MX2	NA	NA	ENSG00000183486	NA	NA	rs45430-T	rs45430	0	45430	intron_variant	FALSE	0.66	3e-8	7.522878745280337	NA	1.1235955	[1.08-1.16]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.66	1.1235955	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	5p15.1	5	17453974	BASP1	LINC02218	NA	NA	ENSG00000249662	NA	NA	rs187843643-T	rs187843643	0	187843643	intron_variant	FALSE	0.01	4e-8	7.3979400086720375	NA	1.96	[1.54-2.48]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.01	1.96	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	5p13.2	5	33951588	SLC45A2	SLC45A2, SLC45A2	NA	NA	ENSG00000164175, ENSG00000281919	NA	NA	rs16891982-?	rs16891982	0	16891982	missense_variant	FALSE	0.96	1e-23	23	NA	2.3809524	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.96	2.3809524	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	22q13.1	22	38148291	PLA2G6	PLA2G6	NA	NA	ENSG00000184381	NA	NA	rs2284063-?	rs2284063	0	2284063	non_coding_transcript_exon_variant	FALSE	0.64	2e-9	8.698970004336019	NA	1.2048193	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.64	1.2048193	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	15q13.1	15	28090674	OCA2	OCA2, OCA2	NA	NA	ENSG00000277361, ENSG00000104044	NA	NA	rs4778138-?	rs4778138	0	4778138	intron_variant	FALSE	0.85	2e-11	10.698970004336019	NA	1.1904762	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.85	1.1904762	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	9p21.3	9	21816529	MTAP, CDKN2A	MTAP	NA	NA	ENSG00000099810	NA	NA	rs7023329-?	rs7023329	0	7023329	intron_variant	FALSE	0.5	7e-9	8.154901959985743	NA	1.1627907	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.5	1.1627907	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	11q22.3	11	108304735	ATM	ATM	NA	NA	ENSG00000149311	NA	NA	rs1801516-?	rs1801516	0	1801516	missense_variant	FALSE	0.86	3e-9	8.522878745280337	NA	1.1363636	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.86	1.1363636	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	1q21.3	1	150887995	ARNT	CTXND2	NA	NA	ENSG00000283324	NA	NA	rs7412746-T	rs7412746	0	7412746	intron_variant	FALSE	0.47	9e-11	10.045757490560675	NA	1.15	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.47	1.15	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	2q33.1	2	201298088	CASP8	FLACC1	NA	NA	ENSG00000155749	NA	NA	rs13016963-A	rs13016963	0	13016963	intron_variant	FALSE	0.38	9e-10	9.045757490560675	NA	1.14	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.38	1.14	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	2p22.2	2	38049406	RMDN2, CYP1B1	RMDN2, RMDN2-AS1	NA	NA	ENSG00000115841, ENSG00000235848	NA	NA	rs6750047-A	rs6750047	0	6750047	intron_variant	FALSE	0.28	7e-9	8.154901959985743	NA	1.1	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.28	1.1	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	6p22.3	6	21163688	CDKAL1	CDKAL1	NA	NA	ENSG00000145996	NA	NA	rs6914598-C	rs6914598	0	6914598	intron_variant	FALSE	0.31	4e-8	7.3979400086720375	NA	1.1	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.31	1.1	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	7p21.1	7	16944656	AGR3	AHR	NA	NA	ENSG00000106546	NA	NA	rs1636744-T	rs1636744	0	1636744	intron_variant	FALSE	0.41	7e-9	8.154901959985743	NA	1.1	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.41	1.1	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	9q31.2	9	106298549	TMEM38B, RAD23B, TAL2	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs10739221-T	rs10739221	0	10739221	intron_variant	FALSE	0.24	7e-11	10.154901959985743	NA	1.13	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.24	1.13	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	10q24.33	10	103909085	OBFC1	STN1	NA	NA	ENSG00000107960	NA	NA	rs2995264-G	rs2995264	0	2995264	intron_variant	FALSE	0.1	2e-9	8.698970004336019	NA	1.17	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.1	1.17	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	11q13.3	11	69552350	CCND1	LINC01488 - CCND1	ENSG00000285094	ENSG00000110092	NA	57398	88806	rs498136-A	rs498136	0	498136	intergenic_variant	TRUE	0.36	2e-12	11.698970004336019	NA	1.12	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.36	1.12	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	16q24.3	16	89689495	MC1R	CDK10	NA	NA	ENSG00000185324	NA	NA	rs258322-A	rs258322	0	258322	intron_variant	FALSE	0.09	3e-27	26.522878745280337	NA	1.67	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.09	1.67	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	16q24.3	16	90000528	AFG3L1P	AFG3L1P	NA	NA	ENSG00000223959	NA	NA	rs4785763-A	rs4785763	0	4785763	non_coding_transcript_exon_variant	FALSE	0.33	6e-22	21.221848749616356	NA	1.32	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.33	1.32	NA
2017-06-06	28212542	Ransohoff KJ	2017-02-09	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/28212542	Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.	Melanoma	4,842 European ancestry cases, 286,565 European ancestry controls	1,804 European ancestry cases, 1,026 European ancestry controls	16q12.2	16	54080912	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs16953002-A	rs16953002	0	16953002	intron_variant	FALSE	0.17	4e-12	11.397940008672037	NA	1.16	[NR]	Illumina [at least 560000] (imputed)	N	melanoma	http://www.ebi.ac.uk/efo/EFO_0000756	GCST004142	Genome-wide genotyping array	0.17	1.16	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	1q31.3	1	193967809	CDC73	NA	NA	NA	NA	NA	NA	rs61406265-?	rs61406265	0	61406265	intron_variant	TRUE	NR	3e-11	10.522878745280337	NA	1.091703	[1.06-1.12]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.091703	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	4p15.1	4	27812319	STIM2	NA	NA	NA	NA	NA	NA	rs7697398-?	rs7697398	0	7697398	intergenic_variant	TRUE	NR	6e-11	10.221848749616356	NA	1.091	[1.063-1.120]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.091	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	1p22.3	1	87708301	LMO4, PKN2	PKN2-AS1	NA	NA	ENSG00000237505	NA	NA	rs12120466-?	rs12120466	0	12120466	intron_variant	FALSE	NR	1e-10	10	NA	1.1695906	[1.12-1.23]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.1695906	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	11q24.2	11	125230542	PKNOX2	PKNOX2	NA	NA	ENSG00000165495	NA	NA	rs7107770-?	rs7107770	0	7107770	intron_variant	FALSE	NR	1e-10	10	NA	1.0928961	[1.06-1.12]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.0928961	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	1p36.23	1	7427217	CAMTA1	CAMTA1	NA	NA	ENSG00000171735	NA	NA	rs10864302-?	rs10864302	0	10864302	intron_variant	FALSE	NR	1e-10	10	NA	1.091703	[1.06-1.12]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.091703	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	5q14.3	5	85224856	EDIL3	RBBP4P6 - NA	ENSG00000248674	NA	NA	34026	NA	rs67177172-?	rs67177172	0	67177172	intergenic_variant	TRUE	NR	1e-10	10	NA	1.07	[1.048-1.092]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.07	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	6p24.3	6	8689984	SLC35B3	HULC	NA	NA	ENSG00000285219	NA	NA	rs1576263-?	rs1576263	0	1576263	intron_variant	FALSE	NR	2e-10	9.698970004336019	NA	1.0672358	[1.05-1.09]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.0672358	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	6q27	6	164736651	C6orf118	NA	NA	NA	NA	NA	NA	rs9347032-?	rs9347032	0	9347032	intergenic_variant	TRUE	NR	3e-10	9.522878745280337	NA	1.069	[1.047-1.091]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.069	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	11p13	11	35664930	TRIM44	TRIM44	NA	NA	ENSG00000166326	NA	NA	rs1174117-?	rs1174117	0	1174117	intron_variant	FALSE	NR	4e-10	9.397940008672037	NA	1.0706638	[1.05-1.09]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.0706638	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	16q21	16	60337597	intergenic	NA - NPAP1L	NA	ENSG00000278499	NA	NA	20858	rs3055140-?	rs3055140	0	3055140	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	NA	1.0718113	[1.05-1.1]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.0718113	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	17q25.3	17	79540864	RBFOX3, HP09025	RBFOX3 - NA	ENSG00000167281	NA	NA	24716	NA	rs35570576-?	rs35570576	0	35570576	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	NA	1.092	[1.061-1.124]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.092	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	6q22.1	6	115192639	FRK	NA	NA	NA	NA	NA	NA	rs4620151-?	rs4620151	0	4620151	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	NA	1.073	[1.049-1.099]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.073	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	5q31.3	5	144761992	KCTD16, PRELID2	NA	NA	NA	NA	NA	NA	rs4349753-?	rs4349753	0	4349753	intergenic_variant	TRUE	NR	4e-9	8.397940008672037	NA	1.0626993	[1.04-1.08]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.0626993	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	16q22.3	16	73600037	ZFHX3, PSMD7	ZFHX3	NA	NA	ENSG00000140836	NA	NA	rs7189864-?	rs7189864	0	7189864	intron_variant	FALSE	NR	4e-9	8.397940008672037	NA	1.069	[1.046-1.094]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.069	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	13q14.11	13	43592860	ENOX1	ENOX1	NA	NA	ENSG00000120658	NA	NA	rs7319075-?	rs7319075	0	7319075	intron_variant	FALSE	NR	4e-9	8.397940008672037	NA	1.085	[1.056-1.116]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.085	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	14q31.2	14	83356382	intergenic	NA	NA	NA	NA	NA	NA	rs11852029-?	rs11852029	0	11852029	intergenic_variant	TRUE	NR	8e-9	8.096910013008056	NA	1.082	[1.053-1.111]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.082	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	2q14.3	2	125227667	CNTNAP5	NA	NA	NA	NA	NA	NA	rs13032103-?	rs13032103	0	13032103	intergenic_variant	TRUE	NR	9e-9	8.045757490560675	NA	1.067	[1.044-1.091]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.067	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	Xq21.1	X	80701050	BRWD3	BRWD3	NA	NA	ENSG00000165288	NA	NA	rs28417201-?	rs28417201	0	28417201	intron_variant	FALSE	NR	9e-9	8.045757490560675	NA	1.057	[1.037-1.077]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.057	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	19q12	19	31488832	TSHZ3, THEG5	TSHZ3-AS1 - LINC02841	ENSG00000267662	ENSG00000267407	NA	71038	31323	rs36061463-?	rs36061463	0	36061463	intergenic_variant	TRUE	NR	1e-8	8	NA	1.0626993	[1.04-1.09]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.0626993	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	7q11.22	7	70547533	AUTS2	AUTS2	NA	NA	ENSG00000158321	NA	NA	rs10234796-?	rs10234796	0	10234796	intron_variant	FALSE	NR	1e-8	8	NA	1.0626993	[1.04-1.09]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.0626993	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	17q22	17	53984105	KIF2B, TOM1L1	NA	NA	NA	NA	NA	NA	rs117147772-?	rs117147772	0	117147772	intron_variant	TRUE	NR	2e-8	7.698970004336019	NA	1.137	[1.087-1.190]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.137	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	13q22.1	13	73763081	KLF12	KLF12	NA	NA	ENSG00000118922	NA	NA	rs9318213-?	rs9318213	0	9318213	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	1.059	[1.038-1.081]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.059	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	NA	NA	NA	FAT3	NA	NA	NA	NA	NA	NA	chr11:92232901:G_GTA-?	chr11:92232901:G_GTA	0	NA	NA	TRUE	NR	3e-8	7.522878745280337	NA	1.0615711	[1.04-1.08]	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.0615711	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Photic sneeze reflex	32,446 European ancestry cases, 67,249 European ancestry controls	NA	2q12.1	2	103473755	TMEM182, LOC100287010	NA - CRLF3P1	NA	ENSG00000236596	NA	NA	20486	rs266053-?	rs266053	0	266053	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	NA	1.06	[1.039-1.083] 	Illumina [13729857] (imputed)	N	autosomal dominant compelling helio-ophthalmic outburst syndrome	http://www.ebi.ac.uk/efo/EFO_0007887	GCST003992	Genome-wide genotyping array	NA	1.06	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	6q16.3	6	104940530	HACE1, LIN28B	LIN28B-AS1, LIN28B	NA	NA	ENSG00000203809, ENSG00000187772	NA	NA	rs7766336-?	rs7766336	0	7766336	intron_variant	FALSE	NR	4e-57	56.39794000867204	NA	0.074	[0.065-0.083] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.074
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	19p13.12	19	14643177	NA	ADGRE3	NA	NA	ENSG00000131355	NA	NA	rs73506161-C	rs73506161	0	73506161	intron_variant	FALSE	NR	6e-6	5.221848749616356	(GLM)	1.3697	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	8p23.2	8	4647009	NA	CSMD1	NA	NA	ENSG00000183117	NA	NA	rs11984453-G	rs11984453	0	11984453	intron_variant	FALSE	NR	7e-6	5.154901959985743	(GLM)	1.8088	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	8q23.1	8	106483376	NA	OXR1	NA	NA	ENSG00000164830	NA	NA	rs73309282-T	rs73309282	0	73309282	intron_variant	FALSE	NR	3e-6	5.522878745280337	(GLM)	1.9187	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	11p15.4	11	7979900	NA	EIF3F	NA	NA	ENSG00000175390	NA	NA	rs10769859-G	rs10769859	0	10769859	intron_variant	FALSE	NR	1e-6	6	(GLM)	2.9542	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	chr8:102010440-T	chr8:102010440	0	NA	NA	TRUE	NR	6e-6	5.221848749616356	(GLM)	3.6429	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	4p11	4	49027406	NA	CWH43	NA	NA	ENSG00000109182	NA	NA	rs77730715-G	rs77730715	0	77730715	intron_variant	FALSE	NR	5e-6	5.301029995663981	(GLM)	3.724	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	chr3:24752415-C	chr3:24752415	0	NA	NA	TRUE	NR	6e-6	5.221848749616356	(GLM)	4.5708	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	1q32.1	1	201075216	NA	CACNA1S	NA	NA	ENSG00000081248	NA	NA	rs3767510-?	rs3767510	0	3767510	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(MLM)	0.1748027	[0.1-0.25] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	14q24.3	14	75398980	NA	NA - JDP2	NA	ENSG00000140044	NA	NA	28736	rs8008002-?	rs8008002	0	8008002	intergenic_variant	TRUE	NR	8e-7	6.096910013008056	(MLM)	0.1891768	[0.11-0.26] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	15q25.2	15	81718161	NA	NA	NA	NA	NA	NA	NA	rs28403489-?	rs28403489	0	28403489	intron_variant	TRUE	NR	8e-6	5.096910013008056	(MLM)	0.1723415	[0.097-0.248] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	9q31.2	9	106581778	NA	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs4335177-?	rs4335177	0	4335177	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(MLM)	0.1834814	[0.11-0.26] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	10p11.23	10	29800065	NA	SVIL - NA	ENSG00000197321	NA	NA	63106	NA	rs3006553-?	rs3006553	0	3006553	regulatory_region_variant	TRUE	NR	8e-6	5.096910013008056	(MLM)	0.186628	[0.11-0.27] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	14q22.2	14	54733816	NA	SAMD4A	NA	NA	ENSG00000020577	NA	NA	rs4901536-?	rs4901536	0	4901536	intron_variant	FALSE	NR	9e-6	5.045757490560675	(MLM)	0.1919267	[0.11-0.28] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	14q24.3	14	77646050	NA	SPTLC2 - COX6CP11	ENSG00000100596	ENSG00000258668	NA	29413	6777	rs59721556-?	rs59721556	0	59721556	TF_binding_site_variant	TRUE	NR	1e-7	7	(MLM)	0.2615917	[0.16-0.36] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	1q31.1	1	189924464	NA	NA	NA	NA	NA	NA	NA	rs34252091-?	rs34252091	0	34252091	intergenic_variant	TRUE	NR	1e-6	6	(MLM)	0.2422166	[0.15-0.34] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	3q26.31	3	171750468	NA	PLD1	NA	NA	ENSG00000075651	NA	NA	rs149053538-?	rs149053538	1	148999439	intron_variant	FALSE	NR	6e-6	5.221848749616356	(MLM)	0.247486	[0.14-0.35] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	18q12.3	18	45832663	NA	SIGLEC15	NA	NA	ENSG00000197046	NA	NA	rs11082490-?	rs11082490	0	11082490	intron_variant	FALSE	NR	2e-6	5.698970004336019	(MLM)	0.2858119	[0.17-0.4] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	14q24.3	14	77902942	NA	ADCK1	NA	NA	ENSG00000063761	NA	NA	rs74065827-?	rs74065827	0	74065827	intron_variant	FALSE	NR	1e-7	7	(MLM)	0.3707302	[0.24-0.51] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	3q21.3	3	126800994	NA	CHCHD6	NA	NA	ENSG00000159685	NA	NA	rs74405815-?	rs74405815	0	74405815	intron_variant	FALSE	NR	3e-6	5.522878745280337	(MLM)	0.3438862	[0.2-0.49] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	6q24.2	6	143544084	NA	PHACTR2	NA	NA	ENSG00000112419	NA	NA	rs6911131-?	rs6911131	0	6911131	intron_variant	FALSE	NR	7e-6	5.154901959985743	(MLM)	0.3302258	[0.19-0.47] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	16p13.3	16	7718742	NA	RBFOX1 - NA	ENSG00000078328	NA	NA	5402	NA	rs9930542-?	rs9930542	0	9930542	intergenic_variant	TRUE	NR	6e-6	5.221848749616356	(MLM)	0.3371169	[0.19-0.48] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	1q32.2	1	207636488	NA	CR1	NA	NA	ENSG00000203710	NA	NA	rs56161922-?	rs56161922	0	56161922	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(MLM)	0.3874831	[0.22-0.55] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	10q26.11	10	117452370	NA	PDZD8 - EMX2OS	ENSG00000165650	ENSG00000229847	NA	76930	20845	rs2532643-?	rs2532643	0	2532643	intron_variant	TRUE	NR	1e-6	6	(MLM)	0.4471507	[0.27-0.63] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	5q33.3	5	156578156	NA	SGCD	NA	NA	ENSG00000170624	NA	NA	rs138538719-?	rs138538719	0	138538719	intron_variant	FALSE	NR	7e-9	8.154901959985743	(MLM)	0.5380868	[0.36-0.72] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	6q22.1	6	117132166	NA	RNA5SP214 - NA	ENSG00000200248	NA	NA	71367	NA	rs142794624-?	rs142794624	0	142794624	intergenic_variant	TRUE	NR	8e-6	5.096910013008056	(MLM)	0.4962775	[0.28-0.71] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	17p11.2	17	19338052	NA	B9D1	NA	NA	ENSG00000108641	NA	NA	rs72838804-C	rs72838804	0	72838804	intron_variant	FALSE	NR	2e-7	6.698970004336019	(GLM)	4.3391	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	17p11.2	17	19008954	NA	SLC5A10	NA	NA	ENSG00000154025	NA	NA	rs111527967-G	rs111527967	0	111527967	intron_variant	FALSE	NR	2e-6	5.698970004336019	(GLM)	4.2893	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	22q13.31	22	47716296	NA	LINC00898 - NA	ENSG00000205634	NA	NA	84727	NA	rs147466853-C	rs147466853	0	147466853	intron_variant	TRUE	NR	2e-6	5.698970004336019	(GLM)	3.7236	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	11q14.2	11	88386364	NA	CTSC - GAPDHP70	ENSG00000109861	ENSG00000249489	NA	26680	21815	rs1451608-G	rs1451608	0	1451608	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	(GLM)	3.2311	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	8p22	8	15786716	NA	TUSC3 - PPM1AP1	ENSG00000104723	ENSG00000250483	NA	20067	19433	rs145847018-G	rs145847018	0	145847018	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(GLM)	3.2111	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	11p12	11	37269808	NA	NA	NA	NA	NA	NA	NA	rs75528631-G	rs75528631	0	75528631	intergenic_variant	TRUE	NR	8e-6	5.096910013008056	(GLM)	3.0592	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	7q21.13	7	89924805	NA	STEAP2-AS1	NA	NA	ENSG00000227646	NA	NA	rs147692810-C	rs147692810	0	147692810	intron_variant	FALSE	NR	5e-6	5.301029995663981	(GLM)	2.9933	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	5q33.3	5	156578156	NA	SGCD	NA	NA	ENSG00000170624	NA	NA	rs138538719-C	rs138538719	0	138538719	intron_variant	FALSE	NR	3e-7	6.522878745280337	(GLM)	2.5963	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	16p13.3	16	7718619	NA	RBFOX1 - NA	ENSG00000078328	NA	NA	5279	NA	rs5020196-C	rs5020196	0	5020196	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(GLM)	2.5638	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	5q33.3	5	156466557	NA	SGCD	NA	NA	ENSG00000170624	NA	NA	rs62382696-A	rs62382696	0	62382696	intron_variant	FALSE	NR	7e-7	6.154901959985743	(GLM)	2.514	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	10q26.11	10	117452370	NA	PDZD8 - EMX2OS	ENSG00000165650	ENSG00000229847	NA	76930	20845	rs2532643-C	rs2532643	0	2532643	intron_variant	TRUE	NR	9e-7	6.045757490560675	(GLM)	2.4204	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	4p16.3	4	2185650	NA	POLN, HAUS3	NA	NA	ENSG00000130997, ENSG00000214367	NA	NA	rs9993696-T	rs9993696	0	9993696	intron_variant	FALSE	NR	3e-6	5.522878745280337	(GLM)	2.1804	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	14q24.3	14	77905060	NA	ADCK1	NA	NA	ENSG00000063761	NA	NA	rs56240334-A	rs56240334	0	56240334	intron_variant	FALSE	NR	2e-7	6.698970004336019	(GLM)	2.0543	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	6q24.2	6	143544084	NA	PHACTR2	NA	NA	ENSG00000112419	NA	NA	rs6911131-A	rs6911131	0	6911131	intron_variant	FALSE	NR	5e-6	5.301029995663981	(GLM)	1.9021	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	21q11.2	21	14869414	NA	LINC02246	NA	NA	ENSG00000281903	NA	NA	rs11439302-G	rs11439302	0	11439302	intron_variant	FALSE	NR	8e-7	6.096910013008056	(GLM)	1.6969	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	14q24.3	14	77643001	NA	SPTLC2 - COX6CP11	ENSG00000100596	ENSG00000258668	NA	26364	9826	rs12434701-C	rs12434701	0	12434701	intergenic_variant	TRUE	NR	1e-6	6	(GLM)	1.3434	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	11q13.1	11	65496424	NA	LINC02736 - MALAT1	ENSG00000279243	ENSG00000251562	NA	7710	1264	rs4102217-G	rs4102217	0	4102217	regulatory_region_variant	TRUE	NR	7e-6	5.154901959985743	(GLM)	1.2945	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	3q26.1	3	166933488	NA	NA	NA	NA	NA	NA	NA	rs73878431-G	rs73878431	0	73878431	intergenic_variant	TRUE	NR	4e-7	6.3979400086720375	(GLM)	1.248	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	7p15.2	7	25763634	NA	NA	NA	NA	NA	NA	NA	rs57425123-A	rs57425123	0	57425123	intergenic_variant	TRUE	NR	8e-6	5.096910013008056	(GLM)	1.1038	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	15q25.2	15	81715972	NA	NA	NA	NA	NA	NA	NA	rs3934047-T	rs3934047	0	3934047	intron_variant	TRUE	NR	3e-6	5.522878745280337	(GLM)	0.9856	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	3q24	3	147221219	NA	NA - RPL21P71	NA	ENSG00000239412	NA	NA	55549	rs6440475-C	rs6440475	0	6440475	intron_variant	TRUE	NR	6e-6	5.221848749616356	(GLM)	0.9637	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	10p11.23	10	29800065	NA	SVIL - NA	ENSG00000197321	NA	NA	63106	NA	rs3006553-G	rs3006553	0	3006553	regulatory_region_variant	TRUE	NR	5e-6	5.301029995663981	(GLM)	1.0728	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	14q24.3	14	75399932	NA	NA - JDP2	NA	ENSG00000140044	NA	NA	27784	rs4903318-G	rs4903318	0	4903318	regulatory_region_variant	TRUE	NR	4e-7	6.3979400086720375	(GLM)	1.0842	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	15q26.1	15	93411839	NA	MYO5A - SEPHS1P2	ENSG00000197535	ENSG00000258787	NA	40882789	18820	rs1906727-C	rs1906727	0	1906727	intron_variant	TRUE	NR	7e-6	5.154901959985743	(GLM)	1.086	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	3q26.1	3	167260917	NA	ZBBX	NA	NA	ENSG00000169064	NA	NA	rs6777098-T	rs6777098	0	6777098	intron_variant	FALSE	NR	8e-6	5.096910013008056	(GLM)	1.1964	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	1p32.3	1	54263191	SSBP3	SSBP3	NA	NA	ENSG00000157216	NA	NA	rs630602-?	rs630602	0	630602	intron_variant	FALSE	NR	1e-8	8	NA	0.026	[0.017-0.034] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.026
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	13q34	13	111539431	TEX29, SOX1	NA - LINC02337	NA	ENSG00000215881	NA	NA	56578	rs35413307-?	rs35413307	0	35413307	intergenic_variant	TRUE	NR	1e-8	8	NA	0.026	[0.017-0.034] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.026
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	12q13.12	12	49856328	BCDIN3D, FAIM2	BCDIN3D - RPL35AP28	ENSG00000186666	ENSG00000242041	NA	13222	6845	rs7306275-?	rs7306275	0	7306275	intergenic_variant	TRUE	NR	1e-8	8	NA	0.027	[0.018-0.036] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.027
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	3p12.1	3	86895788	CADM2, VGLL3	VGLL3	NA	NA	ENSG00000206538	NA	NA	rs13068899-?	rs13068899	0	13068899	intron_variant	FALSE	NR	1e-8	8	NA	0.027	[0.018-0.036] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.027
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	11p14.1	11	30204809	KCNA4, FSHB	KCNA4 - FSHB	ENSG00000182255	ENSG00000131808	NA	187779	26205	rs11031005-?	rs11031005	0	11031005	intron_variant	TRUE	NR	2e-8	7.698970004336019	NA	0.035	[0.047-0.023] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.035
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	9q31.3	9	111547655	ZNF483, PTGR1	ZNF483	NA	NA	ENSG00000173258	NA	NA	rs10217747-?	rs10217747	0	10217747	3_prime_UTR_variant	FALSE	NR	2e-8	7.698970004336019	NA	0.025	[0.017-0.034] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.025
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	2p13.1	2	73512721	ALMS1	ALMS1	NA	NA	ENSG00000116127	NA	NA	rs35273932-?	rs35273932	0	35273932	intron_variant	FALSE	NR	2e-8	7.698970004336019	NA	0.116	[0.075-0.157] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.116
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	8q21.13	8	77203831	PEX2	NA	NA	NA	NA	NA	NA	rs10094574-?	rs10094574	0	10094574	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	NA	0.027	[0.018-0.037] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.027
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	4q24	4	103719907	TACR3, CXXC4	TACR3	NA	NA	ENSG00000169836	NA	NA	rs112217694-?	rs112217694	0	112217694	5_prime_UTR_variant	FALSE	NR	3e-8	7.522878745280337	NA	0.053	[0.072-0.034] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.053
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	5q31.1	5	134570139	PHF15	JADE2	NA	NA	ENSG00000043143	NA	NA	rs13178130-?	rs13178130	0	13178130	intron_variant	FALSE	NR	4e-8	7.3979400086720375	NA	0.025	[0.016-0.034] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.025
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	6p21.1	6	41925585	BYSL	BYSL	NA	NA	ENSG00000112578	NA	NA	rs9349203-?	rs9349203	0	9349203	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.024	[0.015-0.032] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.024
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	18p11.31	18	3816055	DLGAP1	DLGAP1	NA	NA	ENSG00000170579	NA	NA	rs35212912-?	rs35212912	0	35212912	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.03	[0.040-0.019] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.03
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	17q21.33	17	51536424	UTP18, CA10	LINC02073 - CA10	ENSG00000267452	ENSG00000154975	NA	15023	93889	rs9635759-?	rs9635759	0	9635759	regulatory_region_variant	TRUE	NR	1e-10	10	NA	0.03	[0.039-0.021] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.03
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	3q22.1	3	132891908	TMEM108, NPHP3	NPHP3-AS1 - NA	ENSG00000248724	NA	NA	17685	NA	rs6439371-?	rs6439371	0	6439371	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	NA	NA	NA	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	3q27.2	3	185911780	TRA2B, ETV5	IGF2BP2 - TRA2B	ENSG00000073792	ENSG00000136527	NA	86738	2778	rs2002675-?	rs2002675	0	2002675	intergenic_variant	TRUE	NR	6e-7	6.221848749616356	NA	NA	NA	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	11p15.4	11	8617653	TRIM66	TRIM66	NA	NA	ENSG00000166436	NA	NA	rs4929923-?	rs4929923	0	4929923	3_prime_UTR_variant	FALSE	NR	6e-6	5.221848749616356	NA	NA	NA	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	11p15.3	11	13272358	ARNTL	NA - ARNTL	NA	ENSG00000133794	NA	NA	4294	rs900145-?	rs900145	0	900145	intergenic_variant	TRUE	NR	1e-6	6	NA	NA	NA	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	19p13.2	19	9889646	OLFM2	OLFM2	NA	NA	ENSG00000105088	NA	NA	rs1862471-?	rs1862471	0	1862471	intron_variant	FALSE	NR	1e-6	6	NA	NA	NA	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	6q16.3	6	104919741	HACE1, LIN28B	LIN28B-AS1	NA	NA	ENSG00000203809	NA	NA	rs9391253-?	rs9391253	0	9391253	intron_variant	FALSE	NR	1e-23	23	NA	0.058	[0.046-0.069] unit increase	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.058
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	16p13.12	16	14301575	PARN, MKL2	MIR193BHG	NA	NA	ENSG00000262454	NA	NA	rs246185-?	rs246185	0	246185	intron_variant	FALSE	NR	7e-14	13.154901959985743	NA	0.044	[­0.056-0.032] unit decrease	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.044
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	11q24.1	11	122942516	C11orf63	JHY	NA	NA	ENSG00000109944	NA	NA	rs7110373-?	rs7110373	0	7110373	intron_variant	FALSE	NR	2e-13	12.698970004336019	NA	0.04	[0.029-0.050] unit increase	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.04
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	1p31.3	1	65652647	LEPR, PDE4B	LEPR - NA	ENSG00000116678	NA	NA	11088	NA	rs140410685-?	rs140410685	0	140410685	intergenic_variant	TRUE	NR	1e-10	10	NA	0.045	[0.032-0.059] unit increase	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.045
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	9q31.2	9	106149698	TMEM38B, ZNF462	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs9408817-?	rs9408817	0	9408817	intron_variant	FALSE	NR	2e-10	9.698970004336019	NA	0.037	[0.025-0.048] unit increase	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.037
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	Xq26.2	X	131300027	IGSF1, OR13H1	IGSF1	NA	NA	ENSG00000147255	NA	NA	rs5932886-?	rs5932886	0	5932886	intron_variant	FALSE	NR	2e-10	9.698970004336019	NA	0.031	[0.022-0.041] unit increase	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.031
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	Xp22.31	X	8927175	FAM9A, FAM9B	ANAPC15P1 - NOLC1P1	ENSG00000231619	ENSG00000225271	NA	70116	53250	rs5978985-?	rs5978985	0	5978985	intergenic_variant	TRUE	NR	3e-9	8.522878745280337	NA	0.024	[­0.032-0.016] unit decrease	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.024
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	9q31.2	9	106154430	TMEM38B, ZNF462	LINC01505	NA	NA	ENSG00000234323	NA	NA	rs12686569-?	rs12686569	0	12686569	intron_variant	FALSE	NR	2e-34	33.69897000433602	NA	0.057	[0.066-0.048] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.057
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	2p25.3	2	613045	FAM150B, TMEM18	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	66378	50832	rs201205097-?	rs201205097	0	201205097	intergenic_variant	TRUE	NR	3e-15	14.522878745280337	NA	0.044	[0.055-0.033] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.044
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	1q23.3	1	165444407	RXRG	RXRG	NA	NA	ENSG00000143171	NA	NA	rs100537-?	rs100537	0	100537	intron_variant	FALSE	NR	4e-15	14.397940008672037	NA	0.034	[0.042-0.026] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.034
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	14q32.2	14	100380654	WDR25	WDR25	NA	NA	ENSG00000176473	NA	NA	rs12894936-?	rs12894936	0	12894936	intron_variant	FALSE	NR	1e-14	14	NA	0.037	[0.046-0.028] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.037
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	3q13.32	3	117855975	intergenic	NA	NA	NA	NA	NA	NA	rs6438424-?	rs6438424	0	6438424	intron_variant	TRUE	NR	4e-13	12.397940008672037	NA	0.031	[0.023-0.040] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.031
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	14q23.1	14	60423704	PPM1A, C14orf39	C14orf39	NA	NA	ENSG00000179008	NA	NA	rs1254309-?	rs1254309	0	1254309	intron_variant	FALSE	NR	1e-12	12	NA	0.038	[0.028-0.049] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.038
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	16q12.2	16	53769662	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs1558902-?	rs1558902	0	1558902	intron_variant	FALSE	NR	1e-12	12	NA	0.031	[0.023-0.040] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.031
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	1p31.1	1	74512186	FPGT, TNNI3K	LRRC53, TNNI3K, FPGT-TNNI3K	NA	NA	ENSG00000162621, ENSG00000116783, ENSG00000259030	NA	NA	rs1040070-?	rs1040070	0	1040070	intron_variant	FALSE	NR	2e-12	11.698970004336019	NA	0.031	[0.040-0.022] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.031
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	16p13.12	16	14294893	MKL2, PARN	Y_RNA - MIR193BHG	ENSG00000199964	ENSG00000262454	NA	19293	6496	rs1704528-?	rs1704528	0	1704528	intergenic_variant	TRUE	NR	6e-12	11.221848749616356	NA	0.033	[0.042-0.024] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.033
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	Xq26.2	X	131400056	IGSF1, OR13H1	IGSF1	NA	NA	ENSG00000147255	NA	NA	rs762080-?	rs762080	0	762080	intron_variant	FALSE	NR	7e-12	11.154901959985743	NA	0.035	[0.025-0.044] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.035
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	11q24.1	11	122948411	C11orf63	JHY	NA	NA	ENSG00000109944	NA	NA	rs7113019-?	rs7113019	0	7113019	intron_variant	FALSE	NR	7e-12	11.154901959985743	NA	0.03	[0.021-0.038] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.03
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	9q21.32	9	84092374	RMI1, SLC28A3	RMI1 - SLC28A3	ENSG00000178966	ENSG00000197506	NA	88300	183083	rs2378662-?	rs2378662	0	2378662	intron_variant	TRUE	NR	1e-11	11	NA	0.03	[0.021-0.038] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.03
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	18q21.1	18	47273144	SKOR2, SMAD2	SKOR2 - MIR4527HG	ENSG00000215474	ENSG00000267761	NA	21484	12581	rs2048523-?	rs2048523	0	2048523	intron_variant	TRUE	NR	1e-11	11	NA	0.029	[0.038-0.021] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.029
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	2q12.1	2	105254322	GPR45, TGFBRAP1	GPR45 - TGFBRAP1	ENSG00000135973	ENSG00000135966	NA	10855	10069	rs2679894-?	rs2679894	0	2679894	regulatory_region_variant	TRUE	NR	2e-11	10.698970004336019	NA	0.032	[0.042-0.023] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.032
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	1q25.2	1	177903770	FAM5B, SEC16B	NA - SEC16B	NA	ENSG00000120341	NA	NA	20186	rs571567-?	rs571567	0	571567	intron_variant	TRUE	NR	5e-11	10.301029995663981	NA	0.036	[0.025-0.047] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.036
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	16q22.1	16	69701368	NFAT5	NFAT5	NA	NA	ENSG00000102908	NA	NA	rs6499244-?	rs6499244	0	6499244	3_prime_UTR_variant	FALSE	NR	9e-11	10.045757490560675	NA	0.028	[0.020-0.037] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.028
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	6q22.32	6	126530014	CENPW, RSPO3	MIR588 - RNU6-200P	ENSG00000207632	ENSG00000201613	NA	45301	60273	rs1490384-?	rs1490384	0	1490384	intron_variant	TRUE	NR	1e-10	10	NA	0.028	[0.036-0.019] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.028
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	7p14.1	7	41428348	C7orf10, INHBA	NA	NA	NA	NA	NA	NA	rs4141153-?	rs4141153	0	4141153	regulatory_region_variant	TRUE	NR	4e-10	9.397940008672037	NA	0.034	[0.023-0.044] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.034
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	11q23.3	11	115173642	CADM1	CADM1	NA	NA	ENSG00000182985	NA	NA	rs5794958-?	rs5794958	0	5794958	3_prime_UTR_variant	FALSE	NR	1e-9	9	NA	0.031	[0.021-0.041] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.031
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	2q33.1	2	198904459	PLCL1, SATB2	NA	NA	NA	NA	NA	NA	rs1456522-?	rs1456522	0	1456522	intron_variant	TRUE	NR	1e-9	9	NA	0.028	[0.038-0.019] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.028
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	11p14.1	11	27612826	LIN7C, BDNF	BDNF-AS	NA	NA	ENSG00000245573	NA	NA	rs35051342-?	rs35051342	0	35051342	intron_variant	FALSE	NR	1e-9	9	NA	0.032	[0.043-0.022] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.032
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	Xp11.21	X	57413512	FAAH2	FAAH2	NA	NA	ENSG00000165591	NA	NA	rs5914101-?	rs5914101	0	5914101	intron_variant	FALSE	NR	2e-9	8.698970004336019	NA	0.033	[0.022-0.043] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.033
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	10q25.3	10	115724059	ATRNL1	ATRNL1	NA	NA	ENSG00000107518	NA	NA	rs11349289-?	rs11349289	0	11349289	intron_variant	FALSE	NR	3e-9	8.522878745280337	NA	0.027	[0.018-0.036] unit increase	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.027
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	22q13.33	22	49282787	FAM19A5, C22orf34	RPL35P8 - C22orf34	ENSG00000226142	ENSG00000188511	NA	68540	131737	rs11703376-?	rs11703376	0	11703376	intergenic_variant	TRUE	NR	4e-9	8.397940008672037	NA	0.028	[0.038-0.019] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.028
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Menarche (age at onset)	76,831 European ancestry individuals	NA	9q33.3	9	124611184	NR6A1	NR6A1	NA	NA	ENSG00000148200	NA	NA	rs4072705-?	rs4072705	0	4072705	intron_variant	FALSE	NR	1e-8	8	NA	0.025	[0.033-0.016] unit decrease	Illumina [12039492]	N	age at menarche	http://www.ebi.ac.uk/efo/EFO_0004703	GCST003993	Genome-wide genotyping array	NA	NA	0.025
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	20q13.12	20	44210980	OSER1-AS1	OSER1-DT	NA	NA	ENSG00000223891	NA	NA	rs4142441-G	rs4142441	0	4142441	non_coding_transcript_exon_variant	FALSE	0.1541	2e-20	19.69897000433602	NA	0.04678187	[0.037-0.057] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.1541	NA	0.04678187
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	20q13.13	20	50139680	TMEM189-UBE2V1, TMEM189	PEDS1-UBE2V1, PEDS1	NA	NA	ENSG00000124208, ENSG00000240849	NA	NA	rs558811955-C	rs558811955	1	11479032	intron_variant	FALSE	0.3385	3e-16	15.522878745280337	NA	0.03256049	[0.025-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.3385	NA	0.03256049
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	20q13.13	20	50267587	RP11-290F20.3	PELATON	NA	NA	ENSG00000224397	NA	NA	rs6125961-A	rs6125961	0	6125961	non_coding_transcript_exon_variant	FALSE	0.2026	8e-41	40.096910013008056	NA	0.05991248	[0.051-0.069] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2026	NA	0.05991248
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	20q13.13	20	50338887	intergenic	LINC01271 - RN7SL636P	ENSG00000233077	ENSG00000244376	NA	17545	90303	rs913678-C	rs913678	0	913678	regulatory_region_variant	TRUE	0.331	2e-37	36.69897000433602	NA	0.04877176	[0.041-0.056] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.331	NA	0.04877176
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	21q22.2	21	38479032	ERG	ERG	NA	NA	ENSG00000157554	NA	NA	rs80109907-A	rs80109907	0	80109907	intron_variant	FALSE	0.0096	3e-9	8.522878745280337	NA	0.1084824	[0.073-0.144] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0096	NA	0.1084824
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	21q22.2	21	39095717	intergenic	LINC01700 - RPL23AP12	ENSG00000232837	ENSG00000228861	NA	117943	31851	rs2836884-C	rs2836884	0	2836884	intergenic_variant	TRUE	0.2771	7e-9	8.154901959985743	NA	0.02328377	[0.015-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2771	NA	0.02328377
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	22q11.1	22	17105867	IL17RA	IL17RA	NA	NA	ENSG00000177663	NA	NA	rs140221307-C	rs140221307	0	140221307	missense_variant	FALSE	0.0055	3e-78	77.52287874528034	NA	0.4813244	[0.43-0.53] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0055	NA	0.4813244
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	22q11.23	22	24226680	GGT5	GGT5	NA	NA	ENSG00000099998	NA	NA	rs2275984-C	rs2275984	0	2275984	missense_variant	FALSE	0.3078	7e-12	11.154901959985743	NA	0.02649131	[0.019-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.3078	NA	0.02649131
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	22q13.33	22	50525724	SCO2	SCO2	NA	NA	ENSG00000284194	NA	NA	rs131805-C	rs131805	0	131805	intron_variant	FALSE	0.7835	7e-9	8.154901959985743	NA	0.02509494	[0.017-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.7835	NA	0.02509494
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p36.22	1	9181780	RP3-510D11.2	MIR34AHG	NA	NA	ENSG00000228526	NA	NA	rs79412885-A	rs79412885	0	79412885	non_coding_transcript_exon_variant	FALSE	0.077	8e-14	13.096910013008056	NA	0.05139473	[0.038-0.065] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.077	NA	0.05139473
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p36.11	1	26319465	CD52	CD52	NA	NA	ENSG00000169442	NA	NA	rs146201400-GA	rs146201400	0	146201400	intron_variant	FALSE	0.7573	7e-16	15.154901959985743	NA	0.03365638	[0.025-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.7573	NA	0.03365638
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p36.11	1	26778121	ARID1A	ARID1A	NA	NA	ENSG00000117713	NA	NA	rs71636778-C	rs71636778	0	71636778	non_coding_transcript_exon_variant	FALSE	0.1647	6e-12	11.221848749616356	NA	0.03296875	[0.024-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1647	NA	0.03296875
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p34.3	1	35259602	RN7SL136P	Y_RNA - ZMYM4	ENSG00000199964	ENSG00000146463	NA	63540	9107	rs11581846-A	rs11581846	0	11581846	intergenic_variant	TRUE	0.907	1e-9	9	NA	0.03742534	[0.025-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.907	NA	0.03742534
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p34.3	1	36478315	CSF3R	CSF3R	NA	NA	ENSG00000119535	NA	NA	rs3917932-G	rs3917932	0	3917932	intron_variant	FALSE	0.5758	4e-12	11.397940008672037	NA	0.02504407	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5758	NA	0.02504407
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p31.3	1	65671509	intergenic	LEPR - RN7SL854P	ENSG00000116678	ENSG00000239319	NA	29950	89549	rs34293785-C	rs34293785	0	34293785	intergenic_variant	TRUE	0.3664	3e-10	9.522878745280337	NA	0.0234506	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3664	NA	0.0234506
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p22.1	1	92287779	GLMN	GLMN	NA	NA	ENSG00000174842	NA	NA	rs141094656-C	rs141094656	0	141094656	intron_variant	FALSE	0.0164	5e-167	166.30102999566398	NA	0.4129472	[0.38-0.44] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0164	NA	0.4129472
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p22.1	1	92412850	intergenic	RN7SL824P - GFI1	ENSG00000242764	ENSG00000162676	NA	10165	60193	rs115427247-T	rs115427247	0	115427247	intergenic_variant	TRUE	0.0302	1e-35	35	NA	0.1303333	[0.11-0.15] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0302	NA	0.1303333
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p22.1	1	92515679	EVI5	EVI5	NA	NA	ENSG00000067208	NA	NA	rs184721335-G	rs184721335	0	184721335	intron_variant	FALSE	0.0049	7e-11	10.154901959985743	NA	0.195403	[0.14-0.25] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0049	NA	0.195403
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p13.3	1	108202312	SLC25A24	SLC25A24 - NBPF4	ENSG00000284468	ENSG00000196427	NA	1463	20152	rs828999-A	rs828999	0	828999	non_coding_transcript_exon_variant	TRUE	0.5339	6e-9	8.221848749616356	NA	0.02076806	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5339	NA	0.02076806
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1p12	1	117596918	AL157902.3	VPS25P1 - TENT5C	ENSG00000226755	ENSG00000183508	NA	46996	9130	rs17613339-T	rs17613339	0	17613339	non_coding_transcript_exon_variant	TRUE	0.1287	3e-10	9.522878745280337	NA	0.03378121	[0.023-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1287	NA	0.03378121
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q21.3	1	150602219	ENSA	ENSA	NA	NA	ENSG00000143420	NA	NA	rs11204677-G	rs11204677	0	11204677	intron_variant	FALSE	0.5564	3e-41	40.52287874528034	NA	0.0481697	[0.041-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5564	NA	0.0481697
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q21.3	1	150611627	ENSA	ENSA	NA	NA	ENSG00000143420	NA	NA	rs4970966-T	rs4970966	0	4970966	intron_variant	FALSE	0.2251	4e-56	55.39794000867204	NA	0.06773102	[0.059-0.076] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2251	NA	0.06773102
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q21.3	1	153367306	intergenic	S100A9 - S100A12	ENSG00000163220	ENSG00000163221	NA	6283	6405	rs60752752-G	rs60752752	0	60752752	intergenic_variant	TRUE	0.1176	3e-9	8.522878745280337	NA	0.03333822	[0.022-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1176	NA	0.03333822
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	NA	NA	NA	IL6R	NA	NA	NA	NA	NA	NA	chr1:154426970-C	chr1:154426970	0	NA	NA	TRUE	0.4082	9e-10	9.045757490560675	NA	0.02207708	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.4082	NA	0.02207708
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q23.3	1	161185602	ADAMTS4	ADAMTS4	NA	NA	ENSG00000158859	NA	NA	rs4575098-A	rs4575098	0	4575098	3_prime_UTR_variant	FALSE	0.2356	6e-11	10.221848749616356	NA	0.02748434	[0.019-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2356	NA	0.02748434
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	17q12	17	34214325	intergenic	LINC01989 - CCL2	ENSG00000261156	ENSG00000108691	NA	18388	40893	rs9909465-T	rs9909465	0	9909465	intergenic_variant	TRUE	0.2218	1e-9	9	NA	0.02632171	[0.018-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2218	NA	0.02632171
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	17q21.1	17	40007314	RP11-387H17.6	PSMD3 - CSF3	ENSG00000108344	ENSG00000108342	NA	9355	8047	rs12602172-A	rs12602172	0	12602172	intergenic_variant	TRUE	0.3903	2e-132	131.69897000433602	NA	0.08929471	[0.082-0.096] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.3903	NA	0.08929471
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	17q21.1	17	40007650	RP11-387H17.6	PSMD3 - CSF3	ENSG00000108344	ENSG00000108342	NA	9691	7711	rs34762051-C	rs34762051	0	34762051	intergenic_variant	TRUE	0.3767	2e-101	100.69897000433602	NA	0.07938988	[0.072-0.087] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.3767	NA	0.07938988
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	17q21.1	17	40017384	CSF3	CSF3	NA	NA	ENSG00000108342	NA	NA	rs146890554-T	rs146890554	0	146890554	3_prime_UTR_variant	FALSE	0.0135	8e-13	12.096910013008056	NA	0.1130003	[0.082-0.144] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0135	NA	0.1130003
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	17q22	17	58281068	MPO	MPO - TSPOAP1	ENSG00000005381	ENSG00000005379	NA	133	20160	rs34097845-T	rs34097845	0	34097845	intergenic_variant	TRUE	0.0578	9e-57	56.045757490560675	NA	0.1252988	[0.11-0.14] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0578	NA	0.1252988
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	17q23.1	17	59808348	VMP1	VMP1	NA	NA	ENSG00000062716	NA	NA	rs7212590-T	rs7212590	0	7212590	intron_variant	FALSE	0.0797	5e-15	14.301029995663981	NA	0.05144283	[0.039-0.064] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0797	NA	0.05144283
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	17q25.3	17	83114671	intergenic	METRNL - NA	ENSG00000275031	NA	NA	19549	NA	rs140646675-A	rs140646675	0	140646675	intergenic_variant	TRUE	0.4584	4e-31	30.397940008672037	NA	0.04694527	[0.039-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.4584	NA	0.04694527
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	18q23	18	76364065	ZNF516	ZNF516	NA	NA	ENSG00000101493	NA	NA	rs72973714-T	rs72973714	0	72973714	intron_variant	FALSE	0.0679	5e-15	14.301029995663981	NA	0.05582844	[0.042-0.07] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0679	NA	0.05582844
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	NA	NA	NA	S1PR4	NA	NA	NA	NA	NA	NA	chr19:3179884-T	chr19:3179884	0	NA	NA	TRUE	0.0069	2e-9	8.698970004336019	NA	0.1387093	[0.094-0.184] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0069	NA	0.1387093
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19p13.3	19	4997409	KDM4B	KDM4B	NA	NA	ENSG00000127663	NA	NA	rs11881751-A	rs11881751	0	11881751	intron_variant	FALSE	0.2303	1e-12	12	NA	0.03043911	[0.022-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2303	NA	0.03043911
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19p13.3	19	6668961	TNFSF14	TNFSF14	NA	NA	ENSG00000125735	NA	NA	rs1077667-T	rs1077667	0	1077667	intron_variant	FALSE	0.2085	8e-10	9.096910013008056	NA	0.02693343	[0.018-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2085	NA	0.02693343
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19p13.13	19	13023687	NFIX	NFIX	NA	NA	ENSG00000008441	NA	NA	rs1058993-T	rs1058993	0	1058993	intron_variant	FALSE	0.0466	2e-10	9.698970004336019	NA	0.05493343	[0.038-0.072] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0466	NA	0.05493343
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19p13.11	19	18005335	ARRDC2	ARRDC2	NA	NA	ENSG00000105643	NA	NA	rs35928002-G	rs35928002	0	35928002	intron_variant	FALSE	0.3069	3e-14	13.522878745280337	NA	0.03037004	[0.023-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.3069	NA	0.03037004
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19p13.11	19	18294126	intergenic	RPL39P38 - LSM4	ENSG00000241464	ENSG00000130520	NA	8631	12110	rs4808779-G	rs4808779	0	4808779	regulatory_region_variant	TRUE	0.6279	2e-18	17.69897000433602	NA	0.03289263	[0.026-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.6279	NA	0.03289263
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19p13.11	19	18402784	intergenic	LRRC25 - SSBP4	ENSG00000175489	ENSG00000130511	NA	5162	16080	rs1985157-C	rs1985157	0	1985157	regulatory_region_variant	TRUE	0.4123	7e-30	29.154901959985743	NA	0.04115012	[0.034-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.4123	NA	0.04115012
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19q13.11	19	33260946	intergenic	SLC7A10 - CEBPA	ENSG00000130876	ENSG00000245848	NA	35096	38988	rs12151289-C	rs12151289	0	12151289	intergenic_variant	TRUE	0.0316	5e-18	17.30102999566398	NA	0.0907048	[0.07-0.111] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0316	NA	0.0907048
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19q13.11	19	33267695	intergenic	SLC7A10 - CEBPA	ENSG00000130876	ENSG00000245848	NA	41845	32239	rs10413103-C	rs10413103	0	10413103	regulatory_region_variant	TRUE	0.6858	3e-11	10.522878745280337	NA	0.02579829	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.6858	NA	0.02579829
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19q13.31	19	43648948	PLAUR	PLAUR	NA	NA	ENSG00000011422	NA	NA	rs4760-G	rs4760	0	4760	missense_variant	FALSE	0.157	1e-37	37	NA	0.06297125	[0.053-0.073] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.157	NA	0.06297125
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19q13.31	19	43777746	KCNN4	KCNN4	NA	NA	ENSG00000104783	NA	NA	rs11879798-A	rs11879798	0	11879798	intron_variant	FALSE	0.3759	7e-35	34.15490195998574	NA	0.04540951	[0.038-0.053] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.3759	NA	0.04540951
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19q13.41	19	51124509	SIGLEC9	SIGLEC18P - SIGLEC9	ENSG00000268581	ENSG00000129450	NA	1544	397	rs2673908-G	rs2673908	0	2673908	regulatory_region_variant	TRUE	0.5575	2e-10	9.698970004336019	NA	0.02299613	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.5575	NA	0.02299613
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	19q13.42	19	53822958	NLRP12	NLRP12	NA	NA	ENSG00000142405	NA	NA	rs62143206-T	rs62143206	0	62143206	intron_variant	FALSE	0.2106	2e-61	60.69897000433602	NA	0.07251879	[0.064-0.081] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2106	NA	0.07251879
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	20q11.21	20	32324114	KIF3B	KIF3B	NA	NA	ENSG00000101350	NA	NA	rs35786299-GA	rs35786299	0	35786299	intron_variant	FALSE	0.3751	4e-15	14.397940008672037	NA	0.02914055	[0.022-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.3751	NA	0.02914055
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	20q11.21	20	32603213	RP11-410N8.4	NOL4L-DT	NA	NA	ENSG00000204393	NA	NA	rs12480732-T	rs12480732	0	12480732	intron_variant	FALSE	0.2606	3e-44	43.52287874528034	NA	0.05683643	[0.049-0.065] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2606	NA	0.05683643
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	20q12	20	39923465	intergenic	RN7SL680P - HSPE1P1	ENSG00000275337	ENSG00000234878	NA	574073	9457	rs2224539-T	rs2224539	0	2224539	intergenic_variant	TRUE	0.4158	3e-10	9.522878745280337	NA	0.02296433	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.4158	NA	0.02296433
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	20q13.12	20	44209910	OSER1	OSER1	NA	NA	ENSG00000132823	NA	NA	rs2143606-G	rs2143606	0	2143606	intron_variant	FALSE	0.4559	2e-20	19.69897000433602	NA	0.03316579	[0.026-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.4559	NA	0.03316579
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	20q12	20	39164371	Intergenic	NA - LINC01734	NA	ENSG00000230324	NA	NA	49406	rs143677104-A	rs143677104	0	143677104	intergenic_variant	TRUE	1.0	5e-6	5.301029995663981	(AA)	0.562	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97660843	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs58864230-T	rs58864230	0	58864230	intron_variant	FALSE	0.614	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.614	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97585312	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs1911792-G	rs1911792	0	1911792	intron_variant	FALSE	0.678	5e-6	5.301029995663981	(AA)	0.016	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.678	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97600266	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs7662978-C	rs7662978	0	7662978	intron_variant	FALSE	0.558	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.558	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q26.1	3	161163687	Intergenic	NMD3	NA	NA	ENSG00000169251	NA	NA	rs187303806-C	rs187303806	0	187303806	intron_variant	FALSE	1.0	5e-6	5.301029995663981	(AA)	0.432	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97539380	Intergenic	STPG2	NA	NA	ENSG00000163116	NA	NA	rs144910173-C	rs144910173	1	9715661	intron_variant	FALSE	0.7	5e-6	5.301029995663981	(AA)	0.017	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.7	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	92783539	GRID2	GRID2	NA	NA	ENSG00000152208	NA	NA	rs145688504-T	rs145688504	0	145688504	intron_variant	FALSE	0.999	5e-6	5.301029995663981	(AA)	0.412	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97586061	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs72889102-G	rs72889102	0	72889102	intron_variant	FALSE	0.559	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.559	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	14q12	14	27806558	Intergenic	NA	NA	NA	NA	NA	NA	rs111668083-G	rs111668083	0	111668083	intron_variant	TRUE	0.937	5e-6	5.301029995663981	(AA)	0.036	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.937	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	8p23.3	8	1507902	DLGAP2	DLGAP2, DLGAP2, DLGAP2	NA	NA	ENSG00000198010, ENSG00000282318, ENSG00000274161	NA	NA	rs192316701-C	rs192316701	0	192316701	intron_variant	FALSE	0.997	5e-6	5.301029995663981	(AA)	0.163	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.997	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	22q12.3	22	33189162	Intergenic	LARGE1	NA	NA	ENSG00000133424	NA	NA	rs139509979-G	rs139509979	0	139509979	intron_variant	FALSE	0.999	5e-6	5.301029995663981	(AA)	0.41	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97584287	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs72889099-G	rs72889099	0	72889099	intron_variant	FALSE	0.559	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.559	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97587829	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs1508459-G	rs1508459	0	1508459	intron_variant	FALSE	0.559	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.559	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	7q36.1	7	152051389	GALNT11	GALNT11	NA	NA	ENSG00000178234	NA	NA	rs139557951-C	rs139557951	0	139557951	intron_variant	FALSE	0.999	5e-6	5.301029995663981	(AA)	0.384	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	5p15.31	5	7196327	Intergenic	LINC02196	NA	NA	ENSG00000250974	NA	NA	rs186953828-A	rs186953828	0	186953828	intron_variant	FALSE	0.729	5e-6	5.301029995663981	(AA)	0.018	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.729	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97588825	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs61456001-G	rs61456001	0	61456001	intron_variant	FALSE	0.559	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.559	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	12p13.33	12	2249572	CACNA1C	CACNA1C, CACNA1C	NA	NA	ENSG00000151067, ENSG00000285479	NA	NA	rs141955301-T	rs141955301	0	141955301	intron_variant	FALSE	1.0	5e-6	5.301029995663981	(AA)	0.631	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	10p13	10	13631528	PRPF18	PRPF18 - FRMD4A	ENSG00000165630	ENSG00000151474	NA	669	12178	rs138071473-T	rs138071473	0	138071473	intron_variant	TRUE	1.0	5e-6	5.301029995663981	(AA)	0.698	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	19p13.3	19	5908751	VMAC	VMAC	NA	NA	ENSG00000187650	NA	NA	rs111563375-T	rs111563375	0	111563375	intron_variant	FALSE	1.0	5e-6	5.301029995663981	(AA)	0.591	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	2p16.1	2	55929425	Intergenic	EFEMP1 - RN7SKP208	ENSG00000115380	ENSG00000202344	NA	5286	22229	rs180765220-T	rs180765220	0	180765220	regulatory_region_variant	TRUE	0.996	5e-6	5.301029995663981	(AA)	0.168	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.996	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	9q31.1	9	103124098	Intergenic	NA - LINC01492	NA	ENSG00000225564	NA	NA	16425	rs138411828-C	rs138411828	0	138411828	intergenic_variant	TRUE	1.0	5e-6	5.301029995663981	(AA)	0.684	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q12.3	11	62579559	TUT1	TUT1	NA	NA	ENSG00000149016	NA	NA	rs146799327-T	rs146799327	0	146799327	intron_variant	FALSE	0.996	5e-6	5.301029995663981	(AA)	0.155	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.996	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	14q12	14	24105707	NRL	NRL, NRL, PCK2, PCK2	NA	NA	ENSG00000285493, ENSG00000129535, ENSG00000100889, ENSG00000285241	NA	NA	rs146868790-C	rs146868790	0	146868790	intron_variant	FALSE	0.999	5e-6	5.301029995663981	(AA)	0.34	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	7p15.2	7	26517802	Intergenic	NA - KIAA0087	NA	ENSG00000122548	NA	NA	15319	rs1541424-G	rs1541424	0	1541424	intergenic_variant	TRUE	0.161	5e-6	5.301029995663981	(AA)	0.02	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.161	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q26.1	15	92083285	SLCO3A1	SLCO3A1	NA	NA	ENSG00000176463	NA	NA	rs147415896-C	rs147415896	0	147415896	intron_variant	FALSE	0.994	5e-6	5.301029995663981	(AA)	0.137	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.994	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q24.13	8	125494452	TRIB1, LOC100130231	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	56049	365269	rs112875651-G	rs112875651	0	112875651	intron_variant	TRUE	NA	2e-8	7.698970004336019	NA	0.226	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q15.1	15	41042016	INO80	INO80	NA	NA	ENSG00000128908	NA	NA	rs112925537-A	rs112925537	0	112925537	intron_variant	FALSE	NA	2e-10	9.698970004336019	NA	0.413	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q25.2	3	154898030	GPR149, MME	NA	NA	NA	NA	NA	NA	rs113161639-G	rs113161639	0	113161639	intergenic_variant	TRUE	NA	4e-12	11.397940008672037	NA	0.451	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7p22.3	7	2452283	CHST12, MIR4648	CHST12 - GRIFIN	ENSG00000136213	ENSG00000275572	NA	3799	22561	rs11486794-C	rs11486794	0	11486794	regulatory_region_variant	TRUE	NA	3e-7	6.522878745280337	NA	0.304	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17q21.31	17	46121924	KANSL1	KANSL1, KANSL1, KANSL1	NA	NA	ENSG00000120071, ENSG00000275867, ENSG00000278458	NA	NA	rs115231027-T	rs115231027	1	4792830	intron_variant	FALSE	NA	8e-7	6.096910013008056	NA	0.333	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q22.3	11	109148291	DDX10, C11orf87	RNA5SP349 - NA	ENSG00000200613	NA	NA	27305	NA	rs115381894-G	rs115381894	0	115381894	intergenic_variant	TRUE	NA	4e-8	7.3979400086720375	NA	5.212	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q32.2	7	130023656	ZC3HC1	ZC3HC1	NA	NA	ENSG00000091732	NA	NA	rs11556924-C	rs11556924	0	11556924	missense_variant	FALSE	NA	4e-6	5.3979400086720375	NA	0.193	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	21q22.11	21	32416033	FAM176C	CFAP298-TCP10L, EVA1C	NA	NA	ENSG00000265590, ENSG00000166979	NA	NA	rs11701033-C	rs11701033	0	11701033	intron_variant	FALSE	NA	3e-7	6.522878745280337	NA	0.253	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5p13.3	5	32814922	NPR3, LOC340113	NPR3 - NA	ENSG00000113389	NA	NA	23198	NA	rs1173771-A	rs1173771	0	1173771	regulatory_region_variant	TRUE	NA	2e-28	27.69897000433602	NA	0.428	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q33.3	5	158418394	CLINT1, EBF1	LINC02227 - NA	ENSG00000276778	NA	NA	8621	NA	rs11953630-C	rs11953630	0	11953630	intergenic_variant	TRUE	NA	1e-19	19	NA	0.362	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7p12.3	7	45968511	IGFBP3, TNS3	IGFBP3 - FTLP15	ENSG00000146674	ENSG00000233952	NA	46637	29029	rs11977526-G	rs11977526	0	11977526	intron_variant	TRUE	NA	3e-10	9.522878745280337	NA	0.248	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q11.21	8	51024072	SNTG1, PXDNL	NA	NA	NA	NA	NA	NA	rs11993898-T	rs11993898	0	11993898	intergenic_variant	TRUE	NA	4e-11	10.397940008672037	NA	0.326	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p36.22	1	10739520	NR	CASZ1	NA	NA	ENSG00000130940	NA	NA	rs12046278-T	rs12046278	0	12046278	intron_variant	FALSE	NA	5e-18	17.30102999566398	NA	0.367	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	14q11.2	14	23291885	HOMEZ, PPP1R3E	HOMEZ	NA	NA	ENSG00000215271	NA	NA	rs12050260-T	rs12050260	0	12050260	intron_variant	FALSE	NA	3e-7	6.522878745280337	NA	0.21	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10p13	10	12200327	CDC123	CDC123	NA	NA	ENSG00000151465	NA	NA	rs12248718-A	rs12248718	0	12248718	intron_variant	FALSE	NA	7e-7	6.154901959985743	NA	0.21	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1q24.3	1	172388301	DNM3	PIGC, DNM3	NA	NA	ENSG00000135845, ENSG00000197959	NA	NA	rs12405515-G	rs12405515	0	12405515	intron_variant	FALSE	NA	1e-6	6	NA	0.189	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q35	2	215434906	FN1	FN1	NA	NA	ENSG00000115414	NA	NA	rs1250247-C	rs1250247	0	1250247	intron_variant	FALSE	NA	1e-12	12	NA	0.31	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4p11	4	48932281	OCIAD2, CWH43	OCIAD2 - RNU6-158P	ENSG00000145247	ENSG00000252913	NA	25344	474	rs12504699-G	rs12504699	0	12504699	intergenic_variant	TRUE	NA	2e-8	7.698970004336019	NA	0.221	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q21.21	4	80261400	NR	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675	NA	57071	5239	rs12509595-T	rs12509595	0	12509595	intergenic_variant	TRUE	NA	9e-55	54.045757490560675	NA	0.657	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7p14.1	7	40420530	C7orf10	SUGCT	NA	NA	ENSG00000175600	NA	NA	rs12538229-C	rs12538229	0	12538229	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	0.298	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12p12.2	12	20020830	LOC100506393	LINC02398	NA	NA	ENSG00000256287	NA	NA	rs12579720-C	rs12579720	0	12579720	intron_variant	FALSE	NA	5e-6	5.301029995663981	NA	0.199	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16p13.3	16	4896793	PPL	PPL	NA	NA	ENSG00000118898	NA	NA	rs12596053-A	rs12596053	0	12596053	intron_variant	FALSE	NA	2e-12	11.698970004336019	NA	0.275	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	18q12.3	18	44428132	SYT4, SETBP1	LINC01478	NA	NA	ENSG00000267337	NA	NA	rs12606620-G	rs12606620	0	12606620	intron_variant	FALSE	NA	3e-12	11.522878745280337	NA	0.292	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p25.1	3	14912904	FGD5	FGD5	NA	NA	ENSG00000154783	NA	NA	rs12630213-C	rs12630213	0	12630213	intron_variant	FALSE	NA	6e-12	11.221848749616356	NA	0.276	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p13	3	70923315	MITF, FOXP1	NA - FOXP1	NA	ENSG00000114861	NA	NA	31393	rs12636552-A	rs12636552	0	12636552	intergenic_variant	TRUE	NA	5e-9	8.301029995663981	NA	0.241	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7p22.3	7	1692230	TFAMP1, ELFN1	ELFN1	NA	NA	ENSG00000225968	NA	NA	rs12670854-A	rs12670854	0	12670854	intron_variant	FALSE	NA	1e-8	8	NA	0.36	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q33.3	5	158387220	NR	LINC02227	NA	NA	ENSG00000276778	NA	NA	rs12716337-T	rs12716337	0	12716337	intron_variant	FALSE	NA	1e-21	21	NA	0.376	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p23.3	2	26688641	NR	RPL37P11 - KCNK3	ENSG00000225024	ENSG00000171303	NA	10131	4049	rs1275984-A	rs1275984	0	1275984	intergenic_variant	TRUE	NA	2e-33	32.69897000433602	NA	0.473	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p23.3	2	26691496	CIB4, KCNK3	RPL37P11 - KCNK3	ENSG00000225024	ENSG00000171303	NA	12986	1194	rs1275988-C	rs1275988	0	1275988	intergenic_variant	TRUE	NA	4e-33	32.39794000867204	NA	0.467	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.2	11	14617711	PSMA1	PSMA1	NA	NA	ENSG00000129084	NA	NA	rs12787709-G	rs12787709	0	12787709	intron_variant	FALSE	NA	1e-7	7	NA	0.216	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16q23.2	16	81480266	CMIP	CMIP	NA	NA	ENSG00000153815	NA	NA	rs12928482-G	rs12928482	0	12928482	intron_variant	FALSE	NA	4e-6	5.3979400086720375	NA	0.196	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17q21.31	17	45130754	PLCD3	PLCD3	NA	NA	ENSG00000161714	NA	NA	rs12946454-A	rs12946454	0	12946454	intron_variant	FALSE	NA	1e-9	9	NA	0.267	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q31.1	2	174608111	WIPF1	WIPF1	NA	NA	ENSG00000115935	NA	NA	rs13024657-C	rs13024657	0	13024657	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.296	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	21q11.2	21	14971491	NRIP1	NRIP1	NA	NA	ENSG00000180530	NA	NA	rs13050325-A	rs13050325	0	13050325	non_coding_transcript_exon_variant	FALSE	NA	6e-9	8.221848749616356	NA	0.258	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4p14	4	38400562	TBC1D1, FLJ13197	LINC02513 - LINC01258	ENSG00000248227	ENSG00000249534	NA	14803	20100	rs13104866-G	rs13104866	0	13104866	intergenic_variant	TRUE	NA	4e-13	12.397940008672037	NA	0.278	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q24	4	102267552	SLC39A8	SLC39A8	NA	NA	ENSG00000138821	NA	NA	rs13107325-C	rs13107325	0	13107325	missense_variant	FALSE	NA	2e-21	20.69897000433602	NA	0.719	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q24	4	105990585	NPNT, TBCK	NPNT	NA	NA	ENSG00000168743	NA	NA	rs13112725-G	rs13112725	0	13112725	intron_variant	FALSE	NA	2e-11	10.698970004336019	NA	0.297	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q32.1	4	155724361	GUCY1A3	GUCY1A1	NA	NA	ENSG00000164116	NA	NA	rs13139571-C	rs13139571	0	13139571	intron_variant	FALSE	NA	6e-13	12.221848749616356	NA	0.319	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5p13.3	5	32831564	NR	NPR3 - LINC02120	ENSG00000113389	ENSG00000248279	NA	39840	115879	rs13154066-T	rs13154066	0	13154066	regulatory_region_variant	TRUE	NA	2e-29	28.69897000433602	NA	0.436	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q25.1	6	151991280	ESR1	ESR1	NA	NA	ENSG00000091831	NA	NA	rs13192976-A	rs13192976	0	13192976	intron_variant	FALSE	NA	8e-7	6.096910013008056	NA	0.291	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q22.32	6	126794309	CENPW, RSPO3	NA	NA	NA	NA	NA	NA	rs13209747-C	rs13209747	0	13209747	intron_variant	TRUE	NA	7e-17	16.154901959985743	NA	0.322	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20p12.2	20	10988382	JAG1, LOC339593	FAT1P1 - LINC02871	ENSG00000217809	ENSG00000125899	NA	99294	7911	rs1327235-A	rs1327235	0	1327235	intron_variant	TRUE	NA	4e-17	16.397940008672037	NA	0.319	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q23.2	5	123140763	PRDM6	PRDM6	NA	NA	ENSG00000061455	NA	NA	rs13359291-G	rs13359291	0	13359291	intron_variant	FALSE	NA	2e-12	11.698970004336019	NA	0.36	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p21	2	42851618	HAAO, ZFP36L2	CHORDC1P1 - NA	ENSG00000232202	NA	NA	24001	NA	rs13403122-C	rs13403122	0	13403122	intergenic_variant	TRUE	NA	9e-9	8.045757490560675	NA	0.25	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p22.2	2	37290423	PRKD3	PRKD3	NA	NA	ENSG00000115825	NA	NA	rs13420463-A	rs13420463	0	13420463	intron_variant	FALSE	NA	1e-10	10	NA	0.282	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p24.1	2	19531084	OSR1, FLJ12334	LINC01808 - NA	ENSG00000237992	NA	NA	10989	NA	rs1344653-A	rs1344653	0	1344653	intergenic_variant	TRUE	NA	8e-9	8.096910013008056	NA	0.219	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16p13.3	16	2036420	SLC9A3R2	SLC9A3R2	NA	NA	ENSG00000065054	NA	NA	rs139491786-C	rs139491786	0	139491786	missense_variant	FALSE	NA	3e-7	6.522878745280337	NA	1.685	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	9q33.3	9	125175467	PPP6C	PPP6C	NA	NA	ENSG00000119414	NA	NA	rs139703184-T	rs139703184	0	139703184	intron_variant	FALSE	NA	5e-7	6.301029995663981	NA	0.275	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q21.13	8	75679645	HNF4G, ZFHX4-AS1	HNF4G - RNU2-54P	ENSG00000164749	ENSG00000222231	NA	112811	585898	rs1449544-A	rs1449544	0	1449544	intergenic_variant	TRUE	NA	7e-6	5.154901959985743	NA	0.171	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q33.3	5	159977464	ADRA1B, TTC1	ADRA1B - Y_RNA	ENSG00000170214	ENSG00000199964	NA	4452	30981	rs148871069-A	rs148871069	0	148871069	intergenic_variant	TRUE	NA	4e-11	10.397940008672037	NA	2.37	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10p11.22	10	31995897	ARHGAP12, KIF5B	RN7SL825P - KIF5B	ENSG00000239731	ENSG00000170759	NA	3516	13118	rs813412-C	rs813412	0	813412	intergenic_variant	TRUE	NA	7e-6	5.154901959985743	NA	0.202	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p36.22	1	10736809	CASZ1	CASZ1	NA	NA	ENSG00000130940	NA	NA	rs880315-T	rs880315	0	880315	intron_variant	FALSE	NA	5e-17	16.30102999566398	NA	0.364	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	14q13.2	14	35402011	NFKBIA	NFKBIA	NA	NA	ENSG00000100906	NA	NA	rs8904-G	rs8904	0	8904	3_prime_UTR_variant	FALSE	NA	4e-11	10.397940008672037	NA	0.259	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q31.21	4	143266227	USP38, GAB1	USP38 - Y_RNA	ENSG00000170185	ENSG00000199964	NA	42353	43239	rs893929-G	rs893929	0	893929	intergenic_variant	TRUE	NA	2e-9	8.698970004336019	NA	0.233	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q27	6	165761983	PDE10A, LINC00473	PDE10A	NA	NA	ENSG00000112541	NA	NA	rs903432-A	rs903432	0	903432	intron_variant	FALSE	NA	2e-7	6.698970004336019	NA	0.387	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17p13.3	17	2075669	SMG6	SMG6	NA	NA	ENSG00000070366	NA	NA	rs9303241-T	rs9303241	0	9303241	intron_variant	FALSE	NA	2e-7	6.698970004336019	NA	0.204	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	13q34	13	114249688	CDC16	CDC16	NA	NA	ENSG00000130177	NA	NA	rs9314907-C	rs9314907	0	9314907	intron_variant	FALSE	NA	1e-10	10	NA	0.292	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q23.33	10	94136183	PLCE1	PLCE1	NA	NA	ENSG00000138193	NA	NA	rs932764-A	rs932764	0	932764	intron_variant	FALSE	NA	1e-14	14	NA	0.297	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6p24.1	6	12903725	PHACTR1	PHACTR1	NA	NA	ENSG00000112137	NA	NA	rs9349379-A	rs9349379	0	9349379	intron_variant	FALSE	NA	4e-6	5.3979400086720375	NA	0.187	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q15.1	15	40029923	EIF2AK4	EIF2AK4	NA	NA	ENSG00000128829	NA	NA	rs937213-T	rs937213	0	937213	intron_variant	FALSE	NA	2e-10	9.698970004336019	NA	0.256	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	13q13.3	13	35639494	NBEA/MIR548F5	NBEA	NA	NA	ENSG00000172915	NA	NA	rs9565436-A	rs9565436	0	9565436	intron_variant	FALSE	NA	3e-8	7.522878745280337	NA	0.303	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p36.22	1	9381890	SPSB1, SLC25A33	SPSB1 - LINC02606	ENSG00000171621	ENSG00000284693	NA	12358	43204	rs9662255-C	rs9662255	0	9662255	intergenic_variant	TRUE	NA	2e-6	5.698970004336019	NA	0.2	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q32	5	149011577	SH3TC2	SH3TC2	NA	NA	ENSG00000169247	NA	NA	rs9687065-A	rs9687065	0	9687065	intron_variant	FALSE	NA	1e-13	13	NA	0.359	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q25.1	3	150379848	LOC646903, TSC22D2	LINC01214 - TSC22D2	ENSG00000243550	ENSG00000196428	NA	83243	28487	rs9844972-G	rs9844972	0	9844972	intergenic_variant	TRUE	NA	9e-9	8.045757490560675	NA	0.441	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p14.3	3	56667300	FAM208A	TASOR	NA	NA	ENSG00000163946	NA	NA	rs9845655-T	rs9845655	0	9845655	intron_variant	FALSE	NA	3e-7	6.522878745280337	NA	0.215	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q22.3	3	138392909	MRAS	MRAS	NA	NA	ENSG00000158186	NA	NA	rs9864898-C	rs9864898	0	9864898	intron_variant	FALSE	NA	4e-7	6.3979400086720375	NA	0.271	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16p12.3	16	21079970	DNAH3	DNAH3	NA	NA	ENSG00000158486	NA	NA	rs9935770-C	rs9935770	0	9935770	intron_variant	FALSE	NA	5e-9	8.301029995663981	NA	0.223	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10p12.31	10	18419869	CACNB2	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs11014166-A	rs11014166	0	11014166	intron_variant	FALSE	NA	2e-18	17.69897000433602	NA	0.356	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10p12.31	10	18448045	NR	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs11014267-G	rs11014267	0	11014267	intron_variant	FALSE	NA	2e-20	19.69897000433602	NA	0.383	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p14.1	11	27706555	BDNF	BDNF	NA	NA	ENSG00000176697	NA	NA	rs11030119-G	rs11030119	0	11030119	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.196	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p13.2	1	115294125	NGF	NGF, NGF-AS1	NA	NA	ENSG00000134259, ENSG00000228035	NA	NA	rs11102916-C	rs11102916	0	11102916	intron_variant	FALSE	NA	1e-7	7	NA	0.734	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q21.33	12	89632685	NR	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs11105352-G	rs11105352	0	11105352	intron_variant	FALSE	NA	3e-40	39.52287874528034	NA	0.686	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q13.11	12	47809158	HDAC7	HDAC7	NA	NA	ENSG00000061273	NA	NA	rs11168244-C	rs11168244	0	11168244	intron_variant	FALSE	NA	2e-10	9.698970004336019	NA	0.318	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	21q22.3	21	43301147	CRYAA, SIK1	NA - LINC00322	NA	ENSG00000237864	NA	NA	21270	rs112204826-C	rs112204826	0	112204826	intergenic_variant	TRUE	NA	5e-7	6.301029995663981	NA	0.598	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q24.3	11	130403335	ZBTB44, ADAMTS8	ZBTB44-DT	NA	NA	ENSG00000175773	NA	NA	rs11222084-A	rs11222084	0	11222084	non_coding_transcript_exon_variant	FALSE	NA	6e-15	14.221848749616356	NA	0.317	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2017-06-14	28295283	Wang H	2017-03-13	Int J Cancer	www.ncbi.nlm.nih.gov/pubmed/28295283	Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.	Colorectal cancer	1,894 African American ancestry cases, 4,703 African American ancestry controls.	891 African American ancestry cases, 1,150 African American ancestry controls, 1,611 Hispanic ancestry cases, 4,330 Hispanic ancestry controls.	19q13.11	19	33084158	GPATCH1	GPATCH1	NA	NA	ENSG00000076650	NA	NA	rs7252505-G	rs7252505	0	7252505	intron_variant	FALSE	0.38	4e-8	7.3979400086720375	NA	1.19	[1.12-1.27]	Illumina [10050748] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST004168	Genome-wide genotyping array	0.38	1.19	NA
2017-06-14	28295283	Wang H	2017-03-13	Int J Cancer	www.ncbi.nlm.nih.gov/pubmed/28295283	Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.	Colorectal cancer	1,894 African American ancestry cases, 4,703 African American ancestry controls.	891 African American ancestry cases, 1,150 African American ancestry controls, 1,611 Hispanic ancestry cases, 4,330 Hispanic ancestry controls.	19q13.32	19	45818249	SYMPK	SYMPK	NA	NA	ENSG00000125755	NA	NA	rs56848936-A	rs56848936	0	56848936	intron_variant	FALSE	0.94	9e-7	6.045757490560675	(AA)	1.45	[1.25-1.69]	Illumina [10050748] (imputed)	N	colorectal cancer	http://www.ebi.ac.uk/efo/EFO_0005842	GCST004168	Genome-wide genotyping array	0.94	1.45	NA
2017-06-14	28295283	Wang H	2017-03-13	Int J Cancer	www.ncbi.nlm.nih.gov/pubmed/28295283	Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.	Colon cancer	1,451 African American ancestry cases, 4,703 African American ancestry controls.	607 African American ancestry cases, 1,146 African American ancestry controls.	19q13.32	19	45818249	SYMPK	SYMPK	NA	NA	ENSG00000125755	NA	NA	rs56848936-A	rs56848936	0	56848936	intron_variant	FALSE	0.94	2e-8	7.698970004336019	NA	1.64	[1.37-1.92]	Illumina [10050748] (imputed)	N	colonic neoplasm	http://www.ebi.ac.uk/efo/EFO_0004288	GCST004167	Genome-wide genotyping array	0.94	1.64	NA
2017-06-14	28295283	Wang H	2017-03-13	Int J Cancer	www.ncbi.nlm.nih.gov/pubmed/28295283	Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.	Colon cancer	1,451 African American ancestry cases, 4,703 African American ancestry controls.	607 African American ancestry cases, 1,146 African American ancestry controls.	19q13.32	19	45818249	SYMPK	SYMPK	NA	NA	ENSG00000125755	NA	NA	rs56848936-A	rs56848936	0	56848936	intron_variant	FALSE	0.94	5e-7	6.301029995663981	(right-sided colon tumor)	1.79	[1.43-2.22]	Illumina [10050748] (imputed)	N	colonic neoplasm	http://www.ebi.ac.uk/efo/EFO_0004288	GCST004167	Genome-wide genotyping array	0.94	1.79	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p31.3	1	63852664	NR	ROR1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs649195-G; rs631029-G; rs675893-G; rs679386-A; rs636119-C; rs11208300-G; rs11208305-C; rs1390116-G; rs582428-A; rs10889450-T; rs619334-G; rs11581982-C	rs649195; rs631029; rs675893; rs679386; rs636119; rs11208300; rs11208305; rs1390116; rs582428; rs10889450; rs619334; rs11581982	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.032	6e-12	11.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.032	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p31.3	1	63852664	NR	ROR1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs649195-G; rs631029-G; rs675893-G; rs679386-A; rs636119-C; rs11208300-G; rs11208305-C; rs1390116-G; rs582428-A; rs10889450-T; rs619334-G; rs11581982-T	rs649195; rs631029; rs675893; rs679386; rs636119; rs11208300; rs11208305; rs1390116; rs582428; rs10889450; rs619334; rs11581982	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.223	3e-11	10.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.223	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p31.3	1	64150746	NR	ROR1; ROR1-AS1; No mapped genes	NA	NA	NA	NA	NA	rs1324359-G; rs6588083-C	rs1324359; rs6588083	0	NA	intron_variant; intron_variant	NA	0.175	1e-8	8	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.175	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p31.3	1	64877383	JAK1	JAK1; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11208534-A; rs310202-G; rs3790541-C; rs310199-G; rs310201-G	rs11208534; rs310202; rs3790541; rs310199; rs310201	0	NA	intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant	NA	0.003	2e-12	11.698970004336019	NA	45.8	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.003	45.8	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p31.3	1	66225622	NR	PDE4B; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs17128563-A; rs6588190-C; rs12031327-A; rs2153116-T; rs6588191-G	rs17128563; rs6588190; rs12031327; rs2153116; rs6588191	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.955	5e-6	5.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.955	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p31.1	1	76996977	NR	ST6GALNAC5; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4949764-C; rs12065122-A; rs6663942-T; rs6603933-T	rs4949764; rs12065122; rs6663942; rs6603933	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	3e-8	7.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p22.3	1	84793978	NR	N/A - LPAR3; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs9728120-A; rs12062585-A; rs4907096-C; rs4907097-G; rs9324140-G	rs9728120; rs12062585; rs4907096; rs4907097; rs9324140	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant	NA	0.206	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.206	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p22.3	1	84821644	NR	LPAR3; No mapped genes	NA	NA	NA	NA	NA	rs17377758-C; rs9729034-G	rs17377758; rs9729034	0	NA	intron_variant; intron_variant	NA	0.173	7e-6	5.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.173	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p22.3	1	85320068	NR	DDAH1; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs233112-C; rs233111-C; rs233118-C; rs1498373-G	rs233112; rs233111; rs233118; rs1498373	0	NA	3_prime_UTR_variant; 3_prime_UTR_variant; intron_variant; intron_variant	NA	0.029	2e-21	20.69897000433602	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.029	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p22.3	1	85320068	NR	DDAH1; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs233112-C; rs233111-C; rs233118-C; rs1498373-A	rs233112; rs233111; rs233118; rs1498373	0	NA	3_prime_UTR_variant; 3_prime_UTR_variant; intron_variant; intron_variant	NA	0.361	2e-18	17.69897000433602	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.361	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p22.1	1	92118962	NR	BTBD8; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7533077-A; rs492164-G; rs4437922-T; rs2893200-G; rs10875204-G; rs2093879-C; rs563113-T; rs519623-G	rs7533077; rs492164; rs4437922; rs2893200; rs10875204; rs2093879; rs563113; rs519623	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	5e-31	30.30102999566398	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p22.1	1	92118962	NR	BTBD8; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7533077-A; rs492164-G; rs4437922-T; rs2893200-G; rs10875204-G; rs2093879-C; rs563113-G; rs519623-G	rs7533077; rs492164; rs4437922; rs2893200; rs10875204; rs2093879; rs563113; rs519623	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.318	9e-19	18.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.318	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p22.1	1;1	93287725;93350843	NR	CCDC18-AS1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; DR1; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11164890-A; rs2484486-A; rs2783489-T; rs6703310-T; rs12118262-T; rs670254-G; rs626714-T; rs6701250-G; rs1559828-T; rs573056-G; rs6541404-T; rs4847409-C; rs2031225-G; rs7555292-T; rs6692027-G; rs4847408-G; rs519723-G; rs12563120-C; rs6687359-C; rs12133576-A; rs771463-A; rs17131710-T; rs2255722-T; rs506556-C	rs11164890; rs2484486; rs2783489; rs6703310; rs12118262; rs670254; rs626714; rs6701250; rs1559828; rs573056; rs6541404; rs4847409; rs2031225; rs7555292; rs6692027; rs4847408; rs519723; rs12563120; rs6687359; rs12133576; rs771463; rs17131710; rs2255722; rs506556	0	NA	intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; missense_variant; intron_variant	NA	0.0	2e-8	7.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p21.2	1	100561968	NR	GPR88 - LINC01349; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1335751-C; rs10875310-C; rs721385-A; rs12038174-T; rs11166474-C; rs1874779-A; rs4907911-A; rs6692794-C	rs1335751; rs10875310; rs721385; rs12038174; rs11166474; rs1874779; rs4907911; rs6692794	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.001	5e-10	9.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.001	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p21.2	1	101408860	NR	LINC01307 - PLD5; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12142899-C; rs6676848-T; rs11164196-T; rs12401392-A; rs4287203-G	rs12142899; rs6676848; rs11164196; rs12401392; rs4287203	0	NA	regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	1e-7	7	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p21.1	1	103982589	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1330413-T; rs17358695-G; rs4141899-C; rs6586440-T; rs1330408-T; rs17474256-G; rs9435645-A; rs17016893-G; rs10785851-G	rs1330413; rs17358695; rs4141899; rs6586440; rs1330408; rs17474256; rs9435645; rs17016893; rs10785851	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.103	8e-6	5.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.103	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p13.2	1	111360647	NR	CHIAP3; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1856105-T; rs2050605-C; rs1856106-G; rs1856107-C; rs7522707-A	rs1856105; rs2050605; rs1856106; rs1856107; rs7522707	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.005	5e-20	19.30102999566398	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.005	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p13.2	1	111360647	NR	CHIAP3; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1856105-T; rs2050605-T; rs1856106-G; rs1856107-C; rs7522707-A	rs1856105; rs2050605; rs1856106; rs1856107; rs7522707	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.198	1e-7	7	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.198	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p13.2	1	113281675	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs773564-T; rs12073383-A; rs12039095-C; rs1082075-A; rs1418604-C; rs12139764-T; rs773576-G; rs699670-A; rs12564854-G	rs773564; rs12073383; rs12039095; rs1082075; rs1418604; rs12139764; rs773576; rs699670; rs12564854	0	NA	regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	4e-11	10.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p13.2	1	113281675	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs773564-T; rs12073383-A; rs12039095-C; rs1082075-A; rs1418604-C; rs12139764-T; rs773576-G; rs699670-A; rs12564854-A	rs773564; rs12073383; rs12039095; rs1082075; rs1418604; rs12139764; rs773576; rs699670; rs12564854	0	NA	regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.11	4e-7	6.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.11	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p13.2	1	114004104	NR	OLFML3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1553452-C; rs2938327-C; rs6699559-T; rs2938323-A; rs10494164-A; rs2938330-C	rs1553452; rs2938327; rs6699559; rs2938323; rs10494164; rs2938330	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.151	2e-8	7.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.151	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p13.2	1	114004104	NR	OLFML3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1553452-C; rs2938327-C; rs6699559-T; rs2938323-A; rs10494164-A; rs2938330-T	rs1553452; rs2938327; rs6699559; rs2938323; rs10494164; rs2938330	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.1	1e-6	6	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.1	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p12	1;1	119687242;119712503	NR	PHGDH; PHGDH; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11577560-C; rs478093-G; rs11804606-G; rs10494229-A; rs12023426-A; rs636101-T; rs595283-C; rs541763-A	rs11577560; rs478093; rs11804606; rs10494229; rs12023426; rs636101; rs595283; rs541763	0	NA	intron_variant; 5_prime_UTR_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	1e-11	11	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q21.1	1	147349575	NR	LINC00624; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs6658836-T; rs6693109-A; rs17360812-A; rs2883320-G; rs12073316-G; rs9782976-C	rs6658836; rs6693109; rs17360812; rs2883320; rs12073316; rs9782976	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.263	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.263	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q21.3	1	152337610	NR	FLG-AS1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1858483-C; rs11204981-A; rs1858481-G; rs3126088-A; rs1933063-G; rs3134871-A; rs3126087-T; rs1858482-T; rs1858480-G	rs1858483; rs11204981; rs1858481; rs3126088; rs1933063; rs3134871; rs3126087; rs1858482; rs1858480	0	NA	non_coding_transcript_exon_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_exon_variant; intron_variant	NA	0.0	3e-12	11.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17q21.1	17	40007650	RP11-387H17.6	PSMD3 - CSF3	ENSG00000108344	ENSG00000108342	NA	9691	7711	rs34762051-C	rs34762051	0	34762051	intergenic_variant	TRUE	0.3767	1e-152	152	NA	0.09804435	[0.091-0.105] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3767	NA	0.09804435
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17q21.1	17	40017384	CSF3	CSF3	NA	NA	ENSG00000108342	NA	NA	rs146890554-T	rs146890554	0	146890554	3_prime_UTR_variant	FALSE	0.0135	1e-11	11	NA	0.1077541	[0.077-0.139] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0135	NA	0.1077541
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17q23.1	17	59724400	VMP1	VMP1	NA	NA	ENSG00000062716	NA	NA	rs8081395-A	rs8081395	0	8081395	intron_variant	FALSE	0.5454	2e-23	22.69897000433602	NA	0.03567578	[0.029-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5454	NA	0.03567578
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17q25.1	17	74703245	CD300LF, RAB37	RAB37, CD300LF	NA	NA	ENSG00000172794, ENSG00000186074	NA	NA	rs749780-A	rs749780	0	749780	intron_variant	FALSE	0.7316	9e-14	13.045757490560675	NA	0.03030224	[0.022-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.7316	NA	0.03030224
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	18q11.2	18	23571654	NPC1	NPC1	NA	NA	ENSG00000141458	NA	NA	rs147694761-C	rs147694761	1	10618426	intron_variant	FALSE	0.6111	4e-11	10.397940008672037	NA	0.02462545	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.6111	NA	0.02462545
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	18q21.1	18	46265306	C18orf25	C18orf25	NA	NA	ENSG00000152242	NA	NA	rs3744858-T	rs3744858	0	3744858	3_prime_UTR_variant	FALSE	0.7453	5e-10	9.301029995663981	NA	0.02579685	[0.018-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.7453	NA	0.02579685
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	19p13.3	19	1026478	CNN2	RNU6-2 - CNN2	ENSG00000207357	ENSG00000064666	NA	4850	108	rs4807440-T	rs4807440	0	4807440	TF_binding_site_variant	TRUE	0.638	3e-10	9.522878745280337	NA	0.02374496	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.638	NA	0.02374496
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	NA	NA	NA	S1PR4	NA	NA	NA	NA	NA	NA	chr19:3179884-T	chr19:3179884	0	NA	NA	TRUE	0.0069	2e-39	38.69897000433602	NA	0.3023445	[0.26-0.35] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0069	NA	0.3023445
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	19p13.2	19	7782850	CLEC4GP1	CLEC4M - CLEC4GP1	ENSG00000104938	ENSG00000268297	NA	13245	4699	rs1968252-A	rs1968252	0	1968252	intergenic_variant	TRUE	0.2208	3e-10	9.522878745280337	NA	0.02742383	[0.019-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2208	NA	0.02742383
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	19p13.2	19	10297604	ICAM5	ICAM5 - ZGLP1	ENSG00000105376	ENSG00000220201	NA	826	7199	rs35136957-C	rs35136957	0	35136957	intergenic_variant	TRUE	0.3966	2e-11	10.698970004336019	NA	0.02494058	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3966	NA	0.02494058
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	19p13.12	19	13837498	MIR23A, MIR27A, MIR24-2	MIR23AHG	NA	NA	ENSG00000267519	NA	NA	rs10422126-A	rs10422126	0	10422126	non_coding_transcript_exon_variant	FALSE	0.3355	4e-9	8.397940008672037	NA	0.02255107	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3355	NA	0.02255107
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	19p13.11	19	16378636	EPS15L1	EPS15L1	NA	NA	ENSG00000127527	NA	NA	rs78663649-T	rs78663649	0	78663649	intron_variant	FALSE	0.11	1e-29	29	NA	0.06479108	[0.054-0.076] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.11	NA	0.06479108
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	19q13.31	19	43648948	PLAUR	PLAUR	NA	NA	ENSG00000011422	NA	NA	rs4760-G	rs4760	0	4760	missense_variant	FALSE	0.1569	5e-59	58.30102999566398	NA	0.07980459	[0.07-0.089] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1569	NA	0.07980459
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	19q13.32	19	45263471	MARK4	MARK4	NA	NA	ENSG00000007047	NA	NA	rs7255933-A	rs7255933	0	7255933	intron_variant	FALSE	0.2588	4e-40	39.39794000867204	NA	0.05430594	[0.046-0.062] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2588	NA	0.05430594
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	19q13.32	19	47126007	SAE1	SAE1	NA	NA	ENSG00000142230	NA	NA	rs309190-C	rs309190	0	309190	intron_variant	FALSE	0.8945	4e-9	8.397940008672037	NA	0.03460707	[0.023-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.8945	NA	0.03460707
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	19q13.41	19	51224706	CD33	SIGLEC22P - CD33	ENSG00000268849	ENSG00000105383	NA	12618	358	rs3865444-A	rs3865444	0	3865444	regulatory_region_variant	TRUE	0.3241	2e-10	9.698970004336019	NA	0.02439036	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3241	NA	0.02439036
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	20p12.3	20	8628941	PLCB1	PLCB1	NA	NA	ENSG00000182621	NA	NA	rs1883932-T	rs1883932	0	1883932	intron_variant	FALSE	0.5094	3e-11	10.522878745280337	NA	0.02380199	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5094	NA	0.02380199
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	20q12	20	40639545	intergenic	NA - MAFB	NA	ENSG00000204103	NA	NA	46303	rs6102074-T	rs6102074	0	6102074	regulatory_region_variant	TRUE	0.6182	3e-11	10.522878745280337	NA	0.02478046	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.6182	NA	0.02478046
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	NA	NA	NA	LSS	NA	NA	NA	NA	NA	NA	chr21:47633789-G	chr21:47633789	0	NA	NA	TRUE	0.3925	8e-9	8.096910013008056	NA	0.02113035	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3925	NA	0.02113035
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	22q11.1	22	17097075	IL17RA	IL17RA	NA	NA	ENSG00000177663	NA	NA	rs143008696-T	rs143008696	0	143008696	missense_variant	FALSE	0.0053	5e-12	11.301029995663981	NA	0.1842882	[0.13-0.24] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0053	NA	0.1842882
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	22q11.21	22	19984929	ARVCF	ARVCF	NA	NA	ENSG00000099889	NA	NA	rs2238783-G	rs2238783	0	2238783	intron_variant	FALSE	0.3504	9e-11	10.045757490560675	NA	0.02435424	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3504	NA	0.02435424
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	22q12.1	22	28365160	TTC28	TTC28	NA	NA	ENSG00000100154	NA	NA	rs62237617-T	rs62237617	0	62237617	intron_variant	FALSE	0.0029	3e-11	10.522878745280337	NA	0.2473668	[0.17-0.32] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0029	NA	0.2473668
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	22q13.1	22	39136415	CBX7	CBX7	NA	NA	ENSG00000100307	NA	NA	rs713909-C	rs713909	0	713909	non_coding_transcript_exon_variant	FALSE	0.4386	1e-9	9	NA	0.0220845	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4386	NA	0.0220845
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1q23.3	1	161639782	FCGR2B	FCGR3B - FCGR2B	ENSG00000162747	ENSG00000072694	NA	7819	23365	rs201950044-T	rs201950044	0	201950044	intergenic_variant	TRUE	0.1313	1e-11	11	NA	0.03668028	[0.026-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1313	NA	0.03668028
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17q22	17	58279141	MPO	MPO	NA	NA	ENSG00000005381	NA	NA	rs56378716-G	rs56378716	0	56378716	missense_variant	FALSE	0.0127	9e-13	12.045757490560675	NA	0.1142649	[0.083-0.146] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0127	NA	0.1142649
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	9q34.3	9	136425872	PMPCA, INPP5E	PMPCA - INPP5E	ENSG00000165688	ENSG00000148384	NA	2111	2747	rs142483589-C	rs142483589	0	142483589	intergenic_variant	TRUE	0.2893	9e-16	15.045757490560675	NA	0.03178013	[0.024-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2893	NA	0.03178013
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	9q34.3	9	137038475	NPDC1, RP11-229P13.20, C9orf139	C9orf139 - NPDC1	ENSG00000180539	ENSG00000107281	NA	518	988	rs7025728-A	rs7025728	0	7025728	intron_variant	TRUE	0.3285	4e-10	9.397940008672037	NA	0.02399672	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3285	NA	0.02399672
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	10p12.1	10	24922362	PRTFDC1	PRTFDC1	NA	NA	ENSG00000099256	NA	NA	rs12266014-T	rs12266014	0	12266014	intron_variant	FALSE	0.3687	1e-44	44	NA	0.05219243	[0.045-0.059] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.36870000000000003	NA	0.05219243
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	10p12.1	10	28491364	RP11-351M16.3	LINC02652	NA	NA	ENSG00000237128	NA	NA	rs2807743-T	rs2807743	0	2807743	intron_variant	FALSE	0.7693	2e-19	18.69897000433602	NA	0.03858379	[0.03-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.7693	NA	0.03858379
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	NA	NA	NA	CXCL12	NA	NA	NA	NA	NA	NA	chr10:44872361-TAA	chr10:44872361	0	NA	NA	TRUE	0.3029	5e-13	12.301029995663981	NA	0.02882177	[0.021-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3029	NA	0.02882177
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	10q11.23	10	49056159	VSTM4	VSTM4	NA	NA	ENSG00000165633	NA	NA	rs17011726-G	rs17011726	0	17011726	intron_variant	FALSE	0.2348	2e-10	9.698970004336019	NA	0.0269236	[0.019-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2348	NA	0.0269236
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	10q21.3	10	63250912	JMJD1C	JMJD1C	NA	NA	ENSG00000171988	NA	NA	rs10995477-C	rs10995477	0	10995477	intron_variant	FALSE	0.4723	9e-22	21.045757490560675	NA	0.03441704	[0.027-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4723	NA	0.03441704
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	10q22.1	10	71760875	C10orf54	VSIR, CDH23	NA	NA	ENSG00000107738, ENSG00000107736	NA	NA	rs3747869-C	rs3747869	0	3747869	missense_variant	FALSE	0.9005	1e-12	12	NA	0.04254832	[0.031-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.9005	NA	0.04254832
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	10q24.1	10	97314230	RP11-452K12.3	RPL12P27 - FRAT1	ENSG00000237169	ENSG00000165879	NA	4272	5041	rs397933924-CCAGGTTCAAGCGAT	rs397933924	0	397933924	intergenic_variant	TRUE	0.5823	6e-43	42.221848749616356	NA	0.05060343	[0.043-0.058] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5823	NA	0.05060343
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	10q24.32	10	102727686	SFXN2	SFXN2	NA	NA	ENSG00000156398	NA	NA	rs7917772-A	rs7917772	0	7917772	3_prime_UTR_variant	FALSE	0.6316	2e-9	8.698970004336019	NA	0.02219608	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.6316	NA	0.02219608
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	10q26.13	10	124659996	FAM53B, RP11-12J10.3	FAM53B	NA	NA	ENSG00000189319	NA	NA	rs3781454-A	rs3781454	0	3781454	intron_variant	FALSE	0.6785	5e-9	8.301029995663981	NA	0.02252922	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.6785	NA	0.02252922
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	11p15.5	11	307999	IFITM2	IFITM2	NA	NA	ENSG00000185201	NA	NA	rs28521954-G	rs28521954	0	28521954	5_prime_UTR_variant	FALSE	0.3709	1e-36	36	NA	0.04773897	[0.04-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3709	NA	0.04773897
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	11p11.2	11	47866484	intergenic	NUP160 - PTPRJ	ENSG00000030066	ENSG00000149177	NA	17929	114074	rs11039436-C	rs11039436	0	11039436	intergenic_variant	TRUE	0.6683	2e-11	10.698970004336019	NA	0.02713706	[0.019-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.6683	NA	0.02713706
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	11q12.2	11	61803910	FADS1	FADS1, FADS2	NA	NA	ENSG00000149485, ENSG00000134824	NA	NA	rs174549-A	rs174549	0	174549	5_prime_UTR_variant	FALSE	0.309	6e-11	10.221848749616356	NA	0.02525497	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.309	NA	0.02525497
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	11q22.3	11	108471137	C11orf65, AP005718.1	C11orf65 - POGLUT3	ENSG00000166323	ENSG00000178202	NA	3606	975	rs7934719-T	rs7934719	0	7934719	intergenic_variant	TRUE	0.4111	2e-10	9.698970004336019	NA	0.02331543	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4111	NA	0.02331543
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	11q23.2	11	114086475	ZBTB16	ZBTB16	NA	NA	ENSG00000109906	NA	NA	rs2846630-A	rs2846630	0	2846630	intron_variant	FALSE	0.453	3e-10	9.522878745280337	NA	0.02367011	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.453	NA	0.02367011
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	11q23.2	11	114113387	ZBTB16	ZBTB16	NA	NA	ENSG00000109906	NA	NA	rs238914-A	rs238914	0	238914	intron_variant	FALSE	0.3967	3e-10	9.522878745280337	NA	0.02325923	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3967	NA	0.02325923
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	11q23.3	11	118210555	AMICA1	JAML	NA	NA	ENSG00000160593	NA	NA	rs143034248-T	rs143034248	0	143034248	missense_variant	FALSE	0.0059	8e-18	17.096910013008056	NA	0.2138897	[0.17-0.26] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0059	NA	0.2138897
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	11q24.1	11	122629782	intergenic	GLULP3 - UBASH3B	ENSG00000254572	ENSG00000154127	NA	15296	25940	rs140740457-C	rs140740457	0	140740457	regulatory_region_variant	TRUE	0.1268	4e-16	15.397940008672037	NA	0.04440177	[0.034-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1268	NA	0.04440177
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	11q24.3	11	128459018	ETS1	ETS1	NA	NA	ENSG00000134954	NA	NA	rs8705-A	rs8705	0	8705	3_prime_UTR_variant	FALSE	0.319	1e-15	15	NA	0.03147405	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.319	NA	0.03147405
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	12p13.32	12	4225129	intergenic	HSPA8P5 - CCND2-AS1	ENSG00000256356	ENSG00000255920	NA	125610	22852	rs7309743-G	rs7309743	0	7309743	intergenic_variant	TRUE	0.2102	2e-9	8.698970004336019	NA	0.02672119	[0.018-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2102	NA	0.02672119
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	12p13.31	12	6393666	RP1-102E24.8	LTBR - SRP14P1	ENSG00000111321	ENSG00000224906	NA	2095	44832	rs10466905-A	rs10466905	0	10466905	regulatory_region_variant	TRUE	0.1918	3e-18	17.522878745280337	NA	0.0399174	[0.031-0.049] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1918	NA	0.0399174
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	12p13.31	12	9746454	intergenic	CLECL1 - CD69	ENSG00000184293	ENSG00000110848	NA	13155	6032	rs10772108-G	rs10772108	0	10772108	intergenic_variant	TRUE	0.341	4e-15	14.397940008672037	NA	0.02988587	[0.022-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.341	NA	0.02988587
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	NA	NA	NA	FAM186A	NA	NA	NA	NA	NA	NA	chr12:50758821-CA	chr12:50758821	0	NA	NA	TRUE	0.4606	1e-9	9	NA	0.02345185	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4606	NA	0.02345185
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	12q13.13	12	51912002	ACVRL1	ACVRL1	NA	NA	ENSG00000139567	NA	NA	rs1700159-T	rs1700159	0	1700159	intron_variant	FALSE	0.7734	2e-14	13.698970004336019	NA	0.03278325	[0.024-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.7734	NA	0.03278325
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	12q24.12	12	111446804	SH2B3	SH2B3, ATXN2	NA	NA	ENSG00000111252, ENSG00000204842	NA	NA	rs3184504-C	rs3184504	0	3184504	missense_variant	FALSE	0.5175	9e-70	69.04575749056067	NA	0.06308641	[0.056-0.07] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5175	NA	0.06308641
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	12q24.13	12	112191863	HECTD4	HECTD4	NA	NA	ENSG00000173064	NA	NA	rs555346412-C	rs555346412	0	555346412	intron_variant	FALSE	0.0017	7e-10	9.154901959985743	NA	0.2884957	[0.2-0.38] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0017	NA	0.2884957
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	12q24.31	12	123936906	CCDC92	CCDC92	NA	NA	ENSG00000119242	NA	NA	rs9863-C	rs9863	0	9863	3_prime_UTR_variant	FALSE	0.3268	3e-9	8.522878745280337	NA	0.02281002	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3268	NA	0.02281002
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	13q12.2	13	28029870	FLT3	FLT3	NA	NA	ENSG00000122025	NA	NA	rs76428106-C	rs76428106	0	76428106	intron_variant	FALSE	0.0146	2e-19	18.69897000433602	NA	0.1421511	[0.11-0.17] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0146	NA	0.1421511
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	13q12.2	13	28044450	FLT3	FLT3	NA	NA	ENSG00000122025	NA	NA	rs34061361-C	rs34061361	0	34061361	intron_variant	FALSE	0.6379	5e-12	11.301029995663981	NA	0.02592361	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.6379	NA	0.02592361
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	13q33.3	13	108308033	TNFSF13B	TNFSF13B	NA	NA	ENSG00000102524	NA	NA	rs200748895-T	rs200748895	0	200748895	3_prime_UTR_variant	FALSE	0.0213	9e-11	10.045757490560675	NA	0.08764268	[0.061-0.114] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0213	NA	0.08764268
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	14q12	14	24992783	STXBP6	STXBP6	NA	NA	ENSG00000168952	NA	NA	rs2038700-C	rs2038700	0	2038700	intron_variant	FALSE	0.3934	3e-24	23.522878745280337	NA	0.0373641	[0.03-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3934	NA	0.0373641
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	14q24.1	14	68713254	RAD51B	RAD51B	NA	NA	ENSG00000182185	NA	NA	rs10138752-T	rs10138752	0	10138752	intron_variant	FALSE	0.0776	5e-12	11.301029995663981	NA	0.04641403	[0.033-0.06] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0776	NA	0.04641403
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	14q24.3	14	77396337	NOXRED1	NOXRED1	NA	NA	ENSG00000165555	NA	NA	rs11361923-G	rs11361923	0	11361923	intron_variant	FALSE	0.4525	2e-9	8.698970004336019	NA	0.02156262	[0.014-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4525	NA	0.02156262
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	14q32.12	14	92644775	RIN3	RIN3	NA	NA	ENSG00000100599	NA	NA	rs11624512-T	rs11624512	0	11624512	non_coding_transcript_exon_variant	FALSE	0.1921	8e-14	13.096910013008056	NA	0.03407996	[0.025-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1921	NA	0.03407996
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	15q15.1	15	41939155	EHD4	EHD4	NA	NA	ENSG00000103966	NA	NA	rs12101888-T	rs12101888	0	12101888	intron_variant	FALSE	0.2441	4e-16	15.397940008672037	NA	0.033985	[0.026-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2441	NA	0.033985
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	15q15.1	15	41974064	CTD-2382E5.1	PLA2G4E-AS1	NA	NA	ENSG00000246740	NA	NA	rs59868192-A	rs59868192	0	59868192	intron_variant	FALSE	0.1159	7e-18	17.154901959985743	NA	0.04913784	[0.038-0.06] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1159	NA	0.04913784
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	15q21.2	15	50507898	USP50	USP50, USP8	NA	NA	ENSG00000170236, ENSG00000138592	NA	NA	rs3131610-A	rs3131610	0	3131610	3_prime_UTR_variant	FALSE	0.2502	2e-12	11.698970004336019	NA	0.02910776	[0.021-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2502	NA	0.02910776
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	15q22.31	15	64362768	CTD-2116N17.1	CSNK1G1 - PCLAF	ENSG00000169118	ENSG00000166803	NA	6595	1536	rs60606273-T	rs60606273	0	60606273	intron_variant	TRUE	0.9399	3e-12	11.522878745280337	NA	0.05331937	[0.038-0.068] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.9399	NA	0.05331937
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	16p13.3	16	3696240	TRAP1	TRAP1	NA	NA	ENSG00000126602	NA	NA	rs6500550-T	rs6500550	0	6500550	intron_variant	FALSE	0.3028	1e-9	9	NA	0.02400567	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3028	NA	0.02400567
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	16p11.2	16	30474072	ITGAL	ITGAL	NA	NA	ENSG00000005844	NA	NA	rs11574938-C	rs11574938	0	11574938	missense_variant	FALSE	0.5175	6e-27	26.221848749616356	NA	0.03911751	[0.032-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5175	NA	0.03911751
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	16q24.1	16	84549359	TLDC1	MEAK7	NA	NA	ENSG00000140950	NA	NA	rs247826-T	rs247826	0	247826	intron_variant	FALSE	0.2213	4e-25	24.397940008672037	NA	0.04508825	[0.037-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2213	NA	0.04508825
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	16q24.1	16	85982722	RP11-542M13.2	LINC02132 - LINC01082	ENSG00000268804	ENSG00000269186	NA	46499	213232	rs11642657-T	rs11642657	0	11642657	intron_variant	TRUE	0.009	2e-12	11.698970004336019	NA	0.1459982	[0.11-0.19] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.009	NA	0.1459982
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17p13.3	17	2098531	SMG6, RP11-667K14.5	SMG6	NA	NA	ENSG00000070366	NA	NA	rs7225843-C	rs7225843	0	7225843	intron_variant	FALSE	0.2023	7e-13	12.154901959985743	NA	0.03204602	[0.023-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2023	NA	0.03204602
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17p13.2	17	5279909	RABEP1	ZNF594-DT - RABEP1	ENSG00000261879	ENSG00000029725	NA	31727	2356	rs138171347-A	rs138171347	0	138171347	intergenic_variant	TRUE	0.4973	4e-12	11.397940008672037	NA	0.02479711	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4973	NA	0.02479711
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17p13.1	17	7830515	DNAH2	DNAH2	NA	NA	ENSG00000183914	NA	NA	rs34121753-G	rs34121753	0	34121753	intron_variant	FALSE	0.5769	8e-9	8.096910013008056	NA	0.0209492	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5769	NA	0.0209492
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17p11.2	17	16268374	PIGL	PIGL	NA	NA	ENSG00000108474	NA	NA	rs74267027-C	rs74267027	0	74267027	intron_variant	FALSE	0.4785	4e-11	10.397940008672037	NA	0.02381667	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4785	NA	0.02381667
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17q11.2	17	29634544	RP11-68I3.2, SSH2	SSH2, ABHD15-AS1	NA	NA	ENSG00000141298, ENSG00000264031	NA	NA	rs138491296-G	rs138491296	0	138491296	intron_variant	FALSE	0.4405	5e-10	9.301029995663981	NA	0.02241701	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4405	NA	0.02241701
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	NA	NA	NA	ORMDL3	NA	NA	NA	NA	NA	NA	chr17:38080865-G	chr17:38080865	0	NA	NA	TRUE	0.5023	3e-79	78.52287874528034	NA	0.06744331	[0.06-0.074] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5023	NA	0.06744331
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	17q21.1	17	40007042	intergenic	PSMD3 - CSF3	ENSG00000108344	ENSG00000108342	NA	9083	8319	rs12600856-C	rs12600856	0	12600856	intergenic_variant	TRUE	0.3904	8e-185	184.09691001300806	NA	0.1061061	[0.099-0.113] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3904	NA	0.1061061
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1p36.32	1	3774964	SMIM1	SMIM1	NA	NA	ENSG00000235169	NA	NA	rs1175550-G	rs1175550	0	1175550	intron_variant	FALSE	0.2319	1e-49	49	NA	0.06299945	[0.055-0.071] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2319	NA	0.06299945
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1p36.12	1	21673636	RAP1GAP	RAP1GAP - USP48	ENSG00000076864	ENSG00000090686	NA	4273	4662	rs829402-C	rs829402	0	829402	regulatory_region_variant	TRUE	0.2309	5e-23	22.30102999566398	NA	0.0422906	[0.034-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2309	NA	0.0422906
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1p36.12	1	21687978	USP48	USP48	NA	NA	ENSG00000090686	NA	NA	rs17423390-T	rs17423390	0	17423390	intron_variant	FALSE	0.4534	7e-28	27.154901959985743	NA	0.03969738	[0.033-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4534	NA	0.03969738
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1p36.12	1	22375738	intergenic	PPIAP34 - ZBTB40	ENSG00000234397	ENSG00000184677	NA	52407	53100	rs12568930-C	rs12568930	0	12568930	intergenic_variant	TRUE	0.1778	1e-11	11	NA	0.03163588	[0.023-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1778	NA	0.03163588
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1p36.11	1	23839150	HMGCL	HMGCL - FUCA1	ENSG00000117305	ENSG00000179163	NA	530	5927	rs773011284-A	rs773011284	1	58094828	regulatory_region_variant	TRUE	0.4242	1e-12	12	NA	0.0257388	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4242	NA	0.0257388
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1p34.1	1	45547076	AKR1A1	PRDX1 - AKR1A1	ENSG00000117450	ENSG00000117448	NA	4344	3467	rs2991971-G	rs2991971	0	2991971	intergenic_variant	TRUE	0.4229	4e-12	11.397940008672037	NA	0.02543932	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4229	NA	0.02543932
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1p32.2	1	55826667	RP11-90C4.1	NA - LINC01755	NA	ENSG00000233079	NA	NA	41587	rs3935996-A	rs3935996	0	3935996	intron_variant	TRUE	0.4931	7e-30	29.154901959985743	NA	0.04076137	[0.034-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4931	NA	0.04076137
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1p32.2	1	56158423	RP1-158P9.1	NA - RPSAP20	NA	ENSG00000229871	NA	NA	49144	rs778387-G	rs778387	0	778387	intron_variant	TRUE	0.404	7e-36	35.15490195998574	NA	0.0472075	[0.04-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.404	NA	0.0472075
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1p32.2	1	56506681	PPAP2B	PLPP3	NA	NA	ENSG00000162407	NA	NA	rs72664324-A	rs72664324	0	72664324	intron_variant	FALSE	0.0934	5e-16	15.301029995663981	NA	0.04995505	[0.038-0.062] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0934	NA	0.04995505
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1p12	1	117610389	FAM46C	TENT5C	NA	NA	ENSG00000183508	NA	NA	rs11587735-C	rs11587735	0	11587735	intron_variant	FALSE	0.1682	6e-30	29.221848749616356	NA	0.05440789	[0.045-0.064] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1682	NA	0.05440789
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1q21.3	1	150895626	intergenic	CTXND2	NA	NA	ENSG00000283324	NA	NA	rs78132593-A	rs78132593	0	78132593	intron_variant	FALSE	0.2187	4e-9	8.397940008672037	NA	0.02560931	[0.017-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2187	NA	0.02560931
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1q22	1	155291918	PKLR	PKLR, PKLR	NA	NA	ENSG00000262785, ENSG00000143627	NA	NA	rs116100695-A	rs116100695	0	116100695	missense_variant	FALSE	0.0026	1e-9	9	NA	0.249151	[0.17-0.33] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0026	NA	0.249151
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1q22	1	155301643	PKLR	PKLR - FDPS	ENSG00000143627	ENSG00000160752	NA	205	7105	rs141119689-T	rs141119689	0	141119689	intergenic_variant	TRUE	0.069	8e-13	12.096910013008056	NA	0.05145992	[0.037-0.066] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.069	NA	0.05145992
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1q23.1	1	158613814	SPTA1	SPTA1	NA	NA	ENSG00000163554	NA	NA	rs201514157-A	rs201514157	0	201514157	missense_variant	FALSE	7.0E-4	2e-10	9.698970004336019	NA	0.4757698	[0.33-0.62] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	7e-4	NA	0.4757698
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1q23.1	1	158617176	SPTA1	SPTA1	NA	NA	ENSG00000163554	NA	NA	rs2022003-T	rs2022003	0	2022003	intron_variant	FALSE	0.2784	1e-62	62	NA	0.06655619	[0.059-0.074] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2784	NA	0.06655619
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1q23.1	1	158668470	SPTA1	SPTA1	NA	NA	ENSG00000163554	NA	NA	rs140446749-A	rs140446749	0	140446749	intron_variant	FALSE	0.0115	3e-30	29.522878745280337	NA	0.1926948	[0.16-0.23] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0115	NA	0.1926948
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1q25.3	1	183873970	RGL1	RGL1	NA	NA	ENSG00000143344	NA	NA	rs10911457-C	rs10911457	0	10911457	intron_variant	FALSE	0.5259	1e-10	10	NA	0.02324864	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.5259	NA	0.02324864
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	1q32.1	1	199007363	RP11-16L9.3	LINC01222	NA	NA	ENSG00000233410	NA	NA	rs12239179-T	rs12239179	0	12239179	non_coding_transcript_exon_variant	FALSE	0.7535	4e-13	12.397940008672037	NA	0.03016017	[0.022-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.7535	NA	0.03016017
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	KIAA0922	NA	NA	NA	NA	NA	NA	rs10028187-G	chr20:4157072_C_G	0	NA	NA	TRUE	0.3151	3e-10	9.522878745280337	NA	0.02463276	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3151	NA	0.02463276
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	CTD-2288O8.1	NA	NA	NA	NA	NA	NA	rs115421711-G	chr20:57594684_C_T	0	NA	NA	TRUE	0.0412	6e-100	99.22184874961636	NA	0.1915101	[0.17-0.21] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0412	NA	0.1915101
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	PELO	NA	NA	NA	NA	NA	NA	chr5:52095943-A	chr5:52095943	0	NA	NA	TRUE	0.0226	6e-37	36.221848749616356	NA	0.1532993	[0.13-0.18] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0226	NA	0.1532993
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	5q11.2	5	52801055	PELO	PELO, ITGA1	NA	NA	ENSG00000152684, ENSG00000213949	NA	NA	rs1499280-A	rs1499280	0	1499280	missense_variant	FALSE	0.9186	1e-33	33	NA	0.07906187	[0.066-0.092] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.9186	NA	0.07906187
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	5q11.2	5	53975590	ARL15	ARL15	NA	NA	ENSG00000185305	NA	NA	rs702634-A	rs702634	0	702634	intron_variant	FALSE	0.6915	5e-10	9.301029995663981	NA	0.02412668	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.6915	NA	0.02412668
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	5q11.2	5	54381351	LINC01033	LINC01033	NA	NA	ENSG00000249069	NA	NA	rs62355667-A	rs62355667	0	62355667	intron_variant	FALSE	0.1526	1e-11	11	NA	0.03402561	[0.024-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1526	NA	0.03402561
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	5q11.2	5	56561722	AC022431.2	C5orf67	NA	NA	ENSG00000225940	NA	NA	rs547065676-AT	rs547065676	1	11450869	intron_variant	FALSE	0.1908	3e-10	9.522878745280337	NA	0.02901949	[0.02-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1908	NA	0.02901949
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11p15.4	11	10004305	NR	SBF2	NA	NA	ENSG00000133812	NA	NA	rs66803065-C	rs66803065	0	66803065	intron_variant	FALSE	NA	1e-10	10	(EA)	0.474	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11p15.4	11	10004305	NR	SBF2	NA	NA	ENSG00000133812	NA	NA	rs66803065-C	rs66803065	0	66803065	intron_variant	FALSE	NA	1e-10	10	NA	0.448	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p14.1	3	64719689	ADAMTS9-AS2	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs6795735-C	rs6795735	0	6795735	intron_variant	FALSE	NA	3e-8	7.522878745280337	(EA)	0.329	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p14.1	3	64719689	ADAMTS9, AS2	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs6795735-C	rs6795735	0	6795735	intron_variant	FALSE	NA	5e-7	6.301029995663981	NA	0.274	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p21.31	3	48156124	MAP4, CDC25A	RN7SL664P - CDC25A	ENSG00000265078	ENSG00000164045	NA	61019	1022	rs6797587-A	rs6797587	0	6797587	regulatory_region_variant	TRUE	NA	5e-7	6.301029995663981	NA	0.289	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q12.1	11	57889941	CTNND1, OR6Q1	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	NA	16353	27356	rs685149-A	rs685149	0	685149	intergenic_variant	TRUE	NA	5e-7	6.301029995663981	NA	0.299	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q12.1	11	57889941	CTNND1, OR6Q1	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	NA	16353	27356	rs685149-A	rs685149	0	685149	intergenic_variant	TRUE	NA	1e-6	6	(EA)	0.31	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7q32.3	7	131676560	PODXL, PLXNA4	EEF1B2P6 - NDUFB9P2	ENSG00000213261	ENSG00000236281	NA	13936	77186	rs6957161-A	rs6957161	0	6957161	intergenic_variant	TRUE	NA	2e-6	5.698970004336019	NA	0.29	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7q32.3	7	131676560	PODXL, PLXNA4	EEF1B2P6 - NDUFB9P2	ENSG00000213261	ENSG00000236281	NA	13936	77186	rs6957161-A	rs6957161	0	6957161	intergenic_variant	TRUE	NA	5e-6	5.301029995663981	(EA)	0.314	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11p11.2	11	47654618	MTCH2, AGBL2	MTCH2 - AGBL2	ENSG00000109919	ENSG00000165923	NA	12011	4973	rs7107356-A	rs7107356	0	7107356	intergenic_variant	TRUE	NA	9e-7	6.045757490560675	NA	0.265	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11p15.4	11	10328991	ADM, AMPD3	AMPD3	NA	NA	ENSG00000133805	NA	NA	rs7129220-G	rs7129220	0	7129220	intron_variant	FALSE	NA	5e-7	6.301029995663981	NA	0.454	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11p15.4	11	10328991	ADM, AMPD3	AMPD3	NA	NA	ENSG00000133805	NA	NA	rs7129220-G	rs7129220	0	7129220	intron_variant	FALSE	NA	6e-6	5.221848749616356	(EA)	0.43	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q24.12	12	111494996	NR	ATXN2	NA	NA	ENSG00000204842	NA	NA	rs7137828-C	rs7137828	0	7137828	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.266	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q13.13	12	54049306	HOXC4	HOXC4	NA	NA	ENSG00000198353	NA	NA	rs7297416-A	rs7297416	0	7297416	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.274	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q11	11	55587706	OR4C16, OR4C11	OR4C16 - OR4C11	ENSG00000279514	ENSG00000172188	NA	14646	14654	rs74237369-G	rs74237369	0	74237369	intergenic_variant	TRUE	NA	4e-7	6.3979400086720375	NA	0.423	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q11	11	55587706	OR4C16, OR4C11	OR4C16 - OR4C11	ENSG00000279514	ENSG00000172188	NA	14646	14654	rs74237369-G	rs74237369	0	74237369	intergenic_variant	TRUE	NA	1e-6	6	(EA)	0.445	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11p15.5	11	1899025	NR	LINC01150	NA	NA	ENSG00000229671	NA	NA	rs7483477-T	rs7483477	0	7483477	intron_variant	FALSE	NA	3e-8	7.522878745280337	NA	0.344	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11p15.5	11	1899025	NR	LINC01150	NA	NA	ENSG00000229671	NA	NA	rs7483477-T	rs7483477	0	7483477	intron_variant	FALSE	NA	2e-6	5.698970004336019	(EA)	0.326	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	17q21.32	17	46890164	NR	WNT9B - LINC01974	ENSG00000276799	ENSG00000262031	NA	3434	19578	rs75230966-G	rs75230966	0	75230966	regulatory_region_variant	TRUE	NA	5e-9	8.301029995663981	NA	0.54	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	17q21.32	17	46890164	NR	WNT9B - LINC01974	ENSG00000276799	ENSG00000262031	NA	3434	19578	rs75230966-G	rs75230966	0	75230966	regulatory_region_variant	TRUE	NA	3e-7	6.522878745280337	(EA)	0.494	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3q22.2	3	134167861	RYK	RYK	NA	NA	ENSG00000163785	NA	NA	rs75305034-T	rs75305034	1	55688777	intron_variant	FALSE	NA	6e-9	8.221848749616356	NA	0.35	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3q22.2	3	134167861	RYK	RYK	NA	NA	ENSG00000163785	NA	NA	rs75305034-T	rs75305034	1	55688777	intron_variant	FALSE	NA	3e-9	8.522878745280337	(EA)	0.379	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q25	4	108104223	LEF1	LEF1	NA	NA	ENSG00000138795	NA	NA	rs7665304-A	rs7665304	0	7665304	intron_variant	FALSE	NA	5e-6	5.301029995663981	NA	0.251	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p34.2	1	41902364	HIVEP3	HIVEP3	NA	NA	ENSG00000127124	NA	NA	rs783621-A	rs783621	0	783621	intron_variant	FALSE	NA	3e-8	7.522878745280337	NA	0.301	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p34.2	1	41902364	HIVEP3	HIVEP3	NA	NA	ENSG00000127124	NA	NA	rs783621-A	rs783621	0	783621	intron_variant	FALSE	NA	1e-6	6	(EA)	0.29	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q32.2	2	190629685	TMEM194B, NAB1	RN7SKP179 - NAB1	ENSG00000251935	ENSG00000138386	NA	76205	17061	rs6434404-A	rs6434404	0	6434404	intron_variant	TRUE	NA	9e-6	5.045757490560675	(EA)	0.294	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q13.5	11	76414286	PRKRIR, C11orf30	GVQW3	NA	NA	ENSG00000179240	NA	NA	rs7927515-C	rs7927515	0	7927515	3_prime_UTR_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.315	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q13.5	11	76414286	PRKRIR, C11orf30	GVQW3	NA	NA	ENSG00000179240	NA	NA	rs7927515-C	rs7927515	0	7927515	3_prime_UTR_variant	FALSE	NA	2e-7	6.698970004336019	(EA)	0.327	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	19q12	19	31436641	TSHZ3, THEG5	TSHZ3-AS1 - LINC02841	ENSG00000267662	ENSG00000267407	NA	18847	83514	rs8105753-A	rs8105753	0	8105753	regulatory_region_variant	TRUE	NA	4e-8	7.3979400086720375	NA	0.311	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	19q12	19	31436641	TSHZ3, THEG5	TSHZ3-AS1 - LINC02841	ENSG00000267662	ENSG00000267407	NA	18847	83514	rs8105753-A	rs8105753	0	8105753	regulatory_region_variant	TRUE	NA	4e-8	7.3979400086720375	(EA)	0.342	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p36.22	1	10736809	CASZ1	CASZ1	NA	NA	ENSG00000130940	NA	NA	rs880315-T	rs880315	0	880315	intron_variant	FALSE	NA	1e-7	7	NA	0.345	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	15q15.1	15	40029923	EIF2AK4	EIF2AK4	NA	NA	ENSG00000128829	NA	NA	rs937213-T	rs937213	0	937213	intron_variant	FALSE	NA	6e-6	5.221848749616356	NA	0.267	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	16p12.3	16	21079970	DNAH3	DNAH3	NA	NA	ENSG00000158486	NA	NA	rs9935770-C	rs9935770	0	9935770	intron_variant	FALSE	NA	6e-6	5.221848749616356	NA	0.246	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr20:57738070-?	chr20:57738070	0	NA	NA	TRUE	NA	1e-6	6	NA	0.398	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10q24.32	10	102834750	CYP17A1	CYP17A1	NA	NA	ENSG00000148795	NA	NA	rs1004467-A	rs1004467	0	1004467	non_coding_transcript_exon_variant	FALSE	NA	6e-18	17.221848749616356	NA	0.725	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10q24.32	10	102834750	CYP17A1	CYP17A1	NA	NA	ENSG00000148795	NA	NA	rs1004467-A	rs1004467	0	1004467	non_coding_transcript_exon_variant	FALSE	NA	6e-11	10.221848749616356	(EA)	0.657	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7q36.1	7	151717955	PRKAG2	PRKAG2	NA	NA	ENSG00000106617	NA	NA	rs10224002-A	rs10224002	0	10224002	intron_variant	FALSE	NA	4e-7	6.3979400086720375	NA	0.307	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	19p13.2	19	7259335	INSR	INSR	NA	NA	ENSG00000171105	NA	NA	rs10427021-T	rs10427021	0	10427021	intron_variant	FALSE	NA	6e-8	7.221848749616356	(EA)	0.487	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	19p13.2	19	7259335	INSR	INSR	NA	NA	ENSG00000171105	NA	NA	rs10427021-T	rs10427021	0	10427021	intron_variant	FALSE	NA	2e-7	6.698970004336019	NA	0.423	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q13.12	12	50116154	COX14	COX14	NA	NA	ENSG00000178449	NA	NA	rs10747570-A	rs10747570	0	10747570	intron_variant	FALSE	NA	3e-7	6.522878745280337	(EA)	0.313	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q13.12	12	50116154	COX14	COX14	NA	NA	ENSG00000178449	NA	NA	rs10747570-A	rs10747570	0	10747570	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	0.275	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	9q33.2	9	122993292	RABGAP1	RABGAP1	NA	NA	ENSG00000011454	NA	NA	rs10818775-C	rs10818775	0	10818775	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	0.367	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10p12.31	10	18448045	NR	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs11014267-G	rs11014267	0	11014267	intron_variant	FALSE	NA	9e-7	6.045757490560675	NA	0.29	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q21.33	12	89632685	NR	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs11105352-G	rs11105352	0	11105352	intron_variant	FALSE	NA	4e-14	13.397940008672037	NA	0.55	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q21.33	12	89632685	NR	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs11105352-G	rs11105352	0	11105352	intron_variant	FALSE	NA	3e-12	11.522878745280337	(EA)	0.571	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q13.11	12	47809158	HDAC7	HDAC7	NA	NA	ENSG00000061273	NA	NA	rs11168244-C	rs11168244	0	11168244	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	0.353	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q22.3	11	109148291	DDX10, C11orf87	RNA5SP349 - NA	ENSG00000200613	NA	NA	27305	NA	rs115381894-G	rs115381894	0	115381894	intergenic_variant	TRUE	NA	9e-6	5.045757490560675	(AA)	4.774	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q22.3	11	109148291	DDX10, C11orf87	RNA5SP349 - NA	ENSG00000200613	NA	NA	27305	NA	rs115381894-G	rs115381894	0	115381894	intergenic_variant	TRUE	NA	9e-6	5.045757490560675	NA	4.774	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	21q22.11	21	32416033	FAM176C	CFAP298-TCP10L, EVA1C	NA	NA	ENSG00000265590, ENSG00000166979	NA	NA	rs11701033-C	rs11701033	0	11701033	intron_variant	FALSE	NA	9e-6	5.045757490560675	(EA)	0.345	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	21q22.11	21	32416033	FAM176C	CFAP298-TCP10L, EVA1C	NA	NA	ENSG00000265590, ENSG00000166979	NA	NA	rs11701033-C	rs11701033	0	11701033	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	0.336	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007095	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6p21.33	6	31231989	intergenic	HCG27 - HLA-C	ENSG00000220890	ENSG00000228299	NA	28021	36760	rs11967684-A	rs11967684	0	11967684	intergenic_variant	TRUE	0.3428	2e-24	23.69897000433602	NA	0.03858957	[0.031-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3428	NA	0.03858957
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6p21.33	6	31554892	NFKBIL1	NFKBIL1, NFKBIL1, NFKBIL1, NFKBIL1, NFKBIL1, NFKBIL1, NFKBIL1	NA	NA	ENSG00000227565, ENSG00000236346, ENSG00000204498, ENSG00000236196, ENSG00000235125, ENSG00000234530, ENSG00000206440	NA	NA	rs6929796-A	rs6929796	0	6929796	intron_variant	FALSE	0.1635	7e-11	10.154901959985743	NA	0.03154443	[0.022-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1635	NA	0.03154443
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6p21.32	6	32242084	intergenic	NOTCH4 - TSBP1-AS1	ENSG00000206312	ENSG00000225914	NA	18017	12556	rs507778-T	rs507778	0	507778	intergenic_variant	TRUE	0.3256	1e-24	24	NA	0.03915988	[0.032-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3256	NA	0.03915988
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6p21.1	6	43789345	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	2858	55533	rs4711750-A	rs4711750	0	4711750	regulatory_region_variant	TRUE	0.4997	5e-11	10.301029995663981	NA	0.02342795	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4997	NA	0.02342795
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6p12.3	6	47484534	CD2AP	CD2AP	NA	NA	ENSG00000198087	NA	NA	rs9296559-C	rs9296559	0	9296559	intron_variant	FALSE	0.2753	5e-17	16.30102999566398	NA	0.03353401	[0.026-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2753	NA	0.03353401
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6q21	6	108641439	FOXO3	FOXO3	NA	NA	ENSG00000118689	NA	NA	rs9480866-T	rs9480866	0	9480866	intron_variant	FALSE	0.1565	1e-11	11	NA	0.03354746	[0.024-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1565	NA	0.03354746
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6q21	6	109268801	C6orf183	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs9487023-G	rs9487023	0	9487023	intron_variant	FALSE	0.4456	3e-18	17.522878745280337	NA	0.03147124	[0.024-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4456	NA	0.03147124
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6q21	6	110438805	SLC22A16	SLC22A16	NA	NA	ENSG00000004809	NA	NA	rs12210538-G	rs12210538	0	12210538	missense_variant	FALSE	0.2371	4e-17	16.397940008672037	NA	0.03544612	[0.027-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2371	NA	0.03544612
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6q23.2	6	132499141	STX7	STX7	NA	NA	ENSG00000079950	NA	NA	rs147324647-CCT	rs147324647	0	147324647	intron_variant	FALSE	0.455	2e-9	8.698970004336019	NA	0.02184796	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.455	NA	0.02184796
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6q23.3	6	134961518	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs9389248-C	rs9389248	0	9389248	3_prime_UTR_variant	FALSE	0.4354	3e-26	25.522878745280337	NA	0.03820925	[0.031-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4354	NA	0.03820925
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6q24.1	6	139514643	intergenic	LINC01625 - ATP5PBP6	ENSG00000238099	ENSG00000219806	NA	39985	99795	rs668887-A	rs668887	0	668887	intron_variant	TRUE	0.9629	1e-197	197	NA	0.2892717	[0.27-0.31] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.9629	NA	0.2892717
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	6q24.1	6	139519556	intergenic	LINC01625 - ATP5PBP6	ENSG00000238099	ENSG00000219806	NA	44898	94882	rs592423-C	rs592423	0	592423	intron_variant	TRUE	0.5539	5e-284	283.30102999566395	NA	0.1297828	[0.12-0.14] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5539	NA	0.1297828
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	EIF2AK1	NA	NA	NA	NA	NA	NA	chr7:6086610-G	chr7:6086610	0	NA	NA	TRUE	0.0435	4e-19	18.397940008672037	NA	0.07835215	[0.061-0.096] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0435	NA	0.07835215
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	7p21.1	7	16660352	BZW2	BZW2	NA	NA	ENSG00000136261	NA	NA	rs706027-T	rs706027	0	706027	intron_variant	FALSE	0.3809	1e-27	27	NA	0.04043556	[0.033-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3809	NA	0.04043556
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	7p21.1	7	16691417	BZW2	BZW2	NA	NA	ENSG00000136261	NA	NA	rs696281-T	rs696281	0	696281	intron_variant	FALSE	0.2149	5e-29	28.30102999566398	NA	0.04915672	[0.041-0.058] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2149	NA	0.04915672
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	KBTBD2	NA	NA	NA	NA	NA	NA	chr7:32908135-G	chr7:32908135	0	NA	NA	TRUE	0.3746	3e-10	9.522878745280337	NA	0.02321626	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3746	NA	0.02321626
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	7p12.3	7	47417868	TNS3	TNS3	NA	NA	ENSG00000136205	NA	NA	rs865603-A	rs865603	0	865603	intron_variant	FALSE	0.9608	3e-9	8.522878745280337	NA	0.05479809	[0.037-0.073] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.9608	NA	0.05479809
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	7q11.23	7	73627755	MLXIPL	MLXIPL - VPS37D	ENSG00000009950	ENSG00000176428	NA	3212	40076	rs62466318-T	rs62466318	0	62466318	intergenic_variant	TRUE	0.2039	3e-15	14.522878745280337	NA	0.03519386	[0.026-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2039	NA	0.03519386
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	7q22.1	7	100639580	TFR2	TFR2	NA	NA	ENSG00000106327	NA	NA	rs564636753-GA	rs564636753	1	371949132	intron_variant	FALSE	0.2071	2e-12	11.698970004336019	NA	0.03208446	[0.023-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2071	NA	0.03208446
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	7q31.2	7	116560038	CAV1	CAV1	NA	NA	ENSG00000105974	NA	NA	rs9920-C	rs9920	0	9920	3_prime_UTR_variant	FALSE	0.1051	6e-22	21.221848749616356	NA	0.05654402	[0.045-0.068] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1051	NA	0.05654402
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	7q33	7	134697578	intergenic	BPGM - TUBB3P2	ENSG00000172331	ENSG00000230101	NA	17762	37320	rs4728335-C	rs4728335	0	4728335	intergenic_variant	TRUE	0.3502	3e-34	33.52287874528034	NA	0.04572998	[0.038-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3502	NA	0.04572998
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	7q34	7	142954267	KEL	KEL, KEL	NA	NA	ENSG00000276615, ENSG00000197993	NA	NA	rs8176059-A	rs8176059	0	8176059	missense_variant	FALSE	0.0113	7e-9	8.154901959985743	NA	0.09839432	[0.065-0.132] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0113	NA	0.09839432
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8p23.1	8	9169419	RP11-10A14.4	PPP1R3B - NA	ENSG00000173281	NA	NA	17845	NA	rs440932-C	rs440932	0	440932	intron_variant	TRUE	0.3128	5e-20	19.30102999566398	NA	0.0359819	[0.028-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3128	NA	0.0359819
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8p21.2	8	26409318	BNIP3L	BNIP3L	NA	NA	ENSG00000104765	NA	NA	rs3808576-A	rs3808576	0	3808576	intron_variant	FALSE	0.7007	1e-11	11	NA	0.02675944	[0.019-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.7007	NA	0.02675944
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8p11.21	8	41655063	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs6150565-C	rs6150565	0	6150565	3_prime_UTR_variant	FALSE	0.5335	3e-12	11.522878745280337	NA	0.02523244	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5335	NA	0.02523244
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q25.1	15	79454010	NR	MINAR1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7166224-A; rs1415575-C; rs17265891-G; rs10519241-G; rs11630241-T; rs1538133-G; rs16970976-C; rs7168056-T; rs2297773-G; rs2865232-G; rs17180765-G; rs1970291-T; rs6495407-T; rs6495406-T; rs7165922-C	rs7166224; rs1415575; rs17265891; rs10519241; rs11630241; rs1538133; rs16970976; rs7168056; rs2297773; rs2865232; rs17180765; rs1970291; rs6495407; rs6495406; rs7165922	0	NA	intron_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; missense_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.156	8e-8	7.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.156	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q25.1	15	79680538	NR	No mapped genes	NA	NA	NA	NA	NA	rs17279885-A; rs3893384-T	rs17279885; rs3893384	0	NA	regulatory_region_variant; regulatory_region_variant	NA	0.216	2e-10	9.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.216	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q25.1	15	79680538	NR	No mapped genes	NA	NA	NA	NA	NA	rs17279885-G; rs3893384-T	rs17279885; rs3893384	0	NA	regulatory_region_variant; regulatory_region_variant	NA	0.2	1e-6	6	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.2	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q25.1	15	80199111	NR	CTXND1; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1865997-C; rs7180958-A; rs1865996-G; rs12593336-A	rs1865997; rs7180958; rs1865996; rs12593336	0	NA	3_prime_UTR_variant; intron_variant; 3_prime_UTR_variant; 3_prime_UTR_variant	NA	0.11	3e-6	5.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.11	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q25.1	15	80817253	NR	CEMIP; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2055713-G; rs7168261-G; rs12324416-T	rs2055713; rs7168261; rs12324416	0	NA	intron_variant; intron_variant; intron_variant	NA	0.376	5e-20	19.30102999566398	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.376	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q25.1	15	80817253	NR	CEMIP; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2055713-A; rs7168261-G; rs12324416-T	rs2055713; rs7168261; rs12324416	0	NA	intron_variant; intron_variant; intron_variant	NA	0.472	7e-10	9.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.472	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q25.2	15	82796479	NR	FSD2; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4779064-C; rs17158263-C; rs17158267-G; rs12905235-C; rs2379994-T; rs1553883-G; rs2046071-A; rs17841165-T; rs4779068-G	rs4779064; rs17158263; rs17158267; rs12905235; rs2379994; rs1553883; rs2046071; rs17841165; rs4779068	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant	NA	0.005	2e-9	8.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.005	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q25.2	15	82796479	NR	FSD2; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4779064-T; rs17158263-C; rs17158267-G; rs12905235-C; rs2379994-T; rs1553883-G; rs2046071-A; rs17841165-T; rs4779068-G	rs4779064; rs17158263; rs17158267; rs12905235; rs2379994; rs1553883; rs2046071; rs17841165; rs4779068	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant	NA	0.16	5e-6	5.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.16	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q25.3	15	86998692	NR	AGBL1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12101946-G; rs2701405-C; rs11636069-A; rs8038098-G; rs2594330-T; rs6496386-A; rs8023616-T; rs2594333-A; rs8029706-T; rs1583324-G	rs12101946; rs2701405; rs11636069; rs8038098; rs2594330; rs6496386; rs8023616; rs2594333; rs8029706; rs1583324	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.118	3e-6	5.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.118	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q25.3	15	88200163	NR	NTRK3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12324693-A; rs16941424-T; rs2067559-A; rs4887210-C	rs12324693; rs16941424; rs2067559; rs4887210	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.147	8e-8	7.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.147	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q26.1	15	89462468	NR	MIR9-3HG - RHCG; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1371385-A; rs2075833-C; rs8023280-C; rs12439587-G; rs2289352-C; rs1371386-A; rs2075834-G	rs1371385; rs2075833; rs8023280; rs12439587; rs2289352; rs1371386; rs2075834	0	NA	regulatory_region_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant	NA	0.028	2e-9	8.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.028	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q26.1	15	89462468	NR	MIR9-3HG - RHCG; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1371385-A; rs2075833-C; rs8023280-C; rs12439587-G; rs2289352-T; rs1371386-A; rs2075834-G	rs1371385; rs2075833; rs8023280; rs12439587; rs2289352; rs1371386; rs2075834	0	NA	regulatory_region_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant	NA	0.16	8e-8	7.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.16	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q26.1	15	91262031	NR	SV2B; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs16945485-G; rs17595167-A; rs11856372-C	rs16945485; rs17595167; rs11856372	0	NA	intron_variant; intron_variant; intron_variant	NA	0.17	7e-8	7.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.17	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q26.1	15	92563276	NR	C15orf32 - LINC00930; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs8040431-C; rs7183734-C; rs17522931-G; rs4778008-C; rs17703847-C	rs8040431; rs7183734; rs17522931; rs4778008; rs17703847	0	NA	regulatory_region_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant	NA	0.109	7e-6	5.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.109	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q26.2	15	95397582	NR	LINC00924; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12901265-G; rs10520778-A; rs8034653-G; rs10520779-C	rs12901265; rs10520778; rs8034653; rs10520779	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.008	3e-17	16.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.008	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q26.2	15	95397582	NR	LINC00924; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12901265-G; rs10520778-A; rs8034653-G; rs10520779-T	rs12901265; rs10520778; rs8034653; rs10520779	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.222	5e-10	9.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.222	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q26.3	15	101468225	NR	PCSK6; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs9806369-C; rs12905649-G; rs11858490-T; rs12719737-C; rs2047219-G; rs2047220-T; rs4965873-C; rs903552-T; rs11852310-G; rs11858491-T	rs9806369; rs12905649; rs11858490; rs12719737; rs2047219; rs2047220; rs4965873; rs903552; rs11852310; rs11858491	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.002	3e-11	10.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.002	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	15q26.3	15	101468225	NR	PCSK6; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs9806369-A; rs12905649-G; rs11858490-T; rs12719737-C; rs2047219-G; rs2047220-T; rs4965873-C; rs903552-T; rs11852310-G; rs11858491-T	rs9806369; rs12905649; rs11858490; rs12719737; rs2047219; rs2047220; rs4965873; rs903552; rs11852310; rs11858491	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.143	6e-8	7.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.143	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.3	16	2263342	NR	RNPS1; No mapped genes	NA	NA	NA	NA	NA	rs40342-T; rs12599229-G	rs40342; rs12599229	0	NA	intron_variant; non_coding_transcript_exon_variant	NA	0.183	2e-8	7.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.183	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.3	16	3114698	NR	ZNF213-AS1; ZNF205; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2002341-G; rs2717695-A; rs11647815-T; rs909406-T; rs224177-T; rs2717694-C	rs2002341; rs2717695; rs11647815; rs909406; rs224177; rs2717694	0	NA	non_coding_transcript_exon_variant; non_coding_transcript_exon_variant; intron_variant; TF_binding_site_variant; non_coding_transcript_exon_variant; non_coding_transcript_exon_variant	NA	0.0	1e-35	35	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.3	16	3114698	NR	ZNF213-AS1; ZNF205; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2002341-G; rs2717695-A; rs11647815-T; rs909406-T; rs224177-T; rs2717694-T	rs2002341; rs2717695; rs11647815; rs909406; rs224177; rs2717694	0	NA	non_coding_transcript_exon_variant; non_coding_transcript_exon_variant; intron_variant; TF_binding_site_variant; non_coding_transcript_exon_variant; non_coding_transcript_exon_variant	NA	0.388	7e-21	20.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.388	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.3	16	4891046	NR	PPL; No mapped genes	NA	NA	NA	NA	NA	rs760117-T; rs2660243-A	rs760117; rs2660243	0	NA	intron_variant; intron_variant	NA	0.136	2e-7	6.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.136	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.2	16	7924633	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4131337-A; rs4508405-A; rs11646592-C; rs4347607-T; rs4396517-C; rs12596978-G; rs4633701-A; rs7205607-C	rs4131337; rs4508405; rs11646592; rs4347607; rs4396517; rs12596978; rs4633701; rs7205607	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.026	8e-16	15.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.026	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.2	16	7924633	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4131337-A; rs4508405-A; rs11646592-T; rs4347607-T; rs4396517-C; rs12596978-G; rs4633701-A; rs7205607-C	rs4131337; rs4508405; rs11646592; rs4347607; rs4396517; rs12596978; rs4633701; rs7205607	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.26	7e-15	14.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.26	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.2	16	8343360	NR	LINC02152 - N/A; No mapped genes	NA	NA	NA	NA	NA	rs40388-G; rs40387-G	rs40388; rs40387	0	NA	intron_variant; intron_variant	NA	0.301	2e-14	13.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.301	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q25.3	17	77376768	RP11-936I5.1	SEPTIN9	NA	NA	ENSG00000184640	NA	NA	rs4789452-A	rs4789452	0	4789452	non_coding_transcript_exon_variant	FALSE	0.4831	2e-14	13.698970004336019	NA	0.02740594	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4831	NA	0.02740594
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q25.3	17	78123212	TMC6	TMC6	NA	NA	ENSG00000141524	NA	NA	rs3794738-T	rs3794738	0	3794738	intron_variant	FALSE	0.0796	7e-14	13.154901959985743	NA	0.04958273	[0.037-0.063] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0796	NA	0.04958273
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q25.3	17	78128784	TMC6	TMC6	NA	NA	ENSG00000141524	NA	NA	rs2748424-G	rs2748424	0	2748424	intron_variant	FALSE	0.1892	9e-22	21.045757490560675	NA	0.0443136	[0.035-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1892	NA	0.0443136
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q25.3	17	78138386	TMC8	TMC8	NA	NA	ENSG00000167895	NA	NA	rs144120533-T	rs144120533	0	144120533	missense_variant	FALSE	0.0031	3e-11	10.522878745280337	NA	0.22822	[0.16-0.3] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0031	NA	0.22822
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q25.3	17	78248408	THA1P	TMEM235 - THA1P	ENSG00000204278	ENSG00000267676	NA	7421	85	rs72901758-G	rs72901758	0	72901758	non_coding_transcript_exon_variant	TRUE	0.3269	9e-17	16.045757490560675	NA	0.0321627	[0.025-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3269	NA	0.0321627
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	PGS1	NA	NA	NA	NA	NA	NA	chr17:76393675-CCCG	chr17:76393675	0	NA	NA	TRUE	0.4002	6e-9	8.221848749616356	NA	0.0216356	[0.014-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4002	NA	0.0216356
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q25.3	17	80138078	EIF4A3	EIF4A3	NA	NA	ENSG00000141543	NA	NA	rs2361710-C	rs2361710	0	2361710	intron_variant	FALSE	0.4724	2e-22	21.69897000433602	NA	0.03482019	[0.028-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4724	NA	0.03482019
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	18q11.2	18	23469770	RIOK3	RIOK3	NA	NA	ENSG00000101782	NA	NA	rs140271614-A	rs140271614	0	140271614	intron_variant	FALSE	0.0065	3e-13	12.522878745280337	NA	0.179018	[0.13-0.23] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0065	NA	0.179018
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	18q11.2	18	23768176	LAMA3	LAMA3	NA	NA	ENSG00000053747	NA	NA	rs556443619-C	rs556443619	0	556443619	intron_variant	FALSE	0.0058	4e-9	8.397940008672037	NA	0.1483076	[0.099-0.198] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0058	NA	0.1483076
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19p13.3	19	898288	R3HDM4	R3HDM4	NA	NA	ENSG00000198858	NA	NA	rs12985393-T	rs12985393	0	12985393	intron_variant	FALSE	0.2965	1e-10	10	NA	0.02613904	[0.018-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2965	NA	0.02613904
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19p13.3	19	906510	R3HDM4	R3HDM4	NA	NA	ENSG00000198858	NA	NA	rs111932385-A	rs111932385	0	111932385	intron_variant	FALSE	0.0167	4e-24	23.397940008672037	NA	0.1531547	[0.12-0.18] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0167	NA	0.1531547
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19p13.3	19	913048	R3HDM4	R3HDM4	NA	NA	ENSG00000198858	NA	NA	rs1683587-C	rs1683587	0	1683587	intron_variant	FALSE	0.5151	5e-42	41.30102999566398	NA	0.05235026	[0.045-0.06] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5151	NA	0.05235026
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19p13.3	19	1164199	SBNO2	SBNO2	NA	NA	ENSG00000064932	NA	NA	rs35971149-C	rs35971149	0	35971149	intron_variant	FALSE	0.3099	3e-22	21.522878745280337	NA	0.03794556	[0.03-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3099	NA	0.03794556
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19p13.3	19	4502189	HDGFRP2	HDGFL2, PLIN4	NA	NA	ENSG00000167674, ENSG00000167676	NA	NA	rs8887-C	rs8887	0	8887	3_prime_UTR_variant	FALSE	0.5712	1e-12	12	NA	0.02616673	[0.019-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5712	NA	0.02616673
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19p13.2	19	10224049	S1PR2	DNMT1, S1PR2	NA	NA	ENSG00000130816, ENSG00000267534	NA	NA	rs117064827-G	rs117064827	0	117064827	missense_variant	FALSE	0.0085	2e-9	8.698970004336019	NA	0.1239822	[0.084-0.164] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0085	NA	0.1239822
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19p13.2	19	10239973	intergenic	S1PR2 - MRPL4	ENSG00000267534	ENSG00000105364	NA	8642	11928	rs8113613-T	rs8113613	0	8113613	regulatory_region_variant	TRUE	0.1876	3e-29	28.522878745280337	NA	0.05171351	[0.043-0.061] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1876	NA	0.05171351
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	SLC44A2	NA	NA	NA	NA	NA	NA	chr19:10739143-C	chr19:10739143	0	NA	NA	TRUE	0.7766	3e-44	43.52287874528034	NA	0.06016275	[0.052-0.069] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.7766	NA	0.06016275
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19p13.2	19	11181407	KANK2	KANK2	NA	NA	ENSG00000197256	NA	NA	rs74180173-T	rs74180173	0	74180173	intron_variant	FALSE	0.0839	4e-159	158.39794000867204	NA	0.1739449	[0.16-0.19] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0839	NA	0.1739449
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19p13.13	19	12870439	HOOK2, MAST1	HOOK2, MAST1	NA	NA	ENSG00000095066, ENSG00000105613	NA	NA	rs11672387-G	rs11672387	0	11672387	intron_variant	FALSE	0.2174	1e-21	21	NA	0.04172055	[0.033-0.05] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2174	NA	0.04172055
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19p13.11	19	17141231	MYO9B	MYO9B	NA	NA	ENSG00000099331	NA	NA	rs59616136-A	rs59616136	0	59616136	intron_variant	FALSE	0.0966	6e-11	10.221848749616356	NA	0.04021461	[0.028-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0966	NA	0.04021461
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19q13.12	19	35202217	intergenic	FXYD5 - FAM187B	ENSG00000089327	ENSG00000177558	NA	32336	22583	rs28659908-C	rs28659908	0	28659908	intergenic_variant	TRUE	0.4075	1e-20	20	NA	0.03470682	[0.027-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4075	NA	0.03470682
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19q13.32	19	44908822	APOE	APOE	NA	NA	ENSG00000130203	NA	NA	rs7412-T	rs7412	0	7412	missense_variant	FALSE	0.0792	3e-38	37.52287874528034	NA	0.08416118	[0.071-0.097] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0792	NA	0.08416118
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19q13.33	19	48867053	PLEKHA4	PLEKHA4	NA	NA	ENSG00000105559	NA	NA	rs56104184-T	rs56104184	0	56104184	intron_variant	FALSE	0.1876	4e-10	9.397940008672037	NA	0.02866177	[0.02-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1876	NA	0.02866177
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	19q13.33	19	48872268	PLEKHA4, PPP1R15A	PLEKHA4 - PPP1R15A	ENSG00000105559	ENSG00000087074	NA	3651	153	rs17272694-T	rs17272694	0	17272694	TF_binding_site_variant	TRUE	0.0295	1e-14	14	NA	0.08198066	[0.061-0.103] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0295	NA	0.08198066
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	20p13	20	4144492	SMOX	SMOX	NA	NA	ENSG00000088826	NA	NA	rs6084646-T	rs6084646	0	6084646	intron_variant	FALSE	0.3847	3e-13	12.522878745280337	NA	0.02725132	[0.02-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3847	NA	0.02725132
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	RN7SL546P	NA	NA	NA	NA	NA	NA	chr14:103044709-GA	chr14:103044709	0	NA	NA	TRUE	0.2944	3e-10	9.522878745280337	NA	0.02498835	[0.017-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2944	NA	0.02498835
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	15q15.1	15	40014133	EIF2AK4	EIF2AK4	NA	NA	ENSG00000128829	NA	NA	rs12050884-A	rs12050884	0	12050884	intron_variant	FALSE	0.2068	1e-9	9	NA	0.02700095	[0.018-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2068	NA	0.02700095
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	15q22.2	15	62508256	TLN2	TLN2	NA	NA	ENSG00000171914	NA	NA	rs812957-G	rs812957	0	812957	intron_variant	FALSE	0.2737	2e-22	21.69897000433602	NA	0.0391755	[0.031-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2737	NA	0.0391755
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	15q22.2	15	62800701	TLN2	TLN2	NA	NA	ENSG00000171914	NA	NA	rs35997243-C	rs35997243	0	35997243	missense_variant	FALSE	0.0146	4e-15	14.397940008672037	NA	0.1170721	[0.088-0.146] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0146	NA	0.1170721
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	15q22.31	15	63506371	USP3	USP3	NA	NA	ENSG00000140455	NA	NA	rs35639661-G	rs35639661	0	35639661	intron_variant	FALSE	0.6465	4e-12	11.397940008672037	NA	0.02610743	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.6465	NA	0.02610743
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	15q25.1	15	80054439	intergenic	BCL2A1 - Metazoa_SRP	ENSG00000140379	ENSG00000278007	NA	83243	2986	rs34483751-A	rs34483751	0	34483751	regulatory_region_variant	TRUE	0.6368	1e-10	10	NA	0.02428426	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.6368	NA	0.02428426
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	16p13.3	16	93505	NPRL3	NPRL3	NA	NA	ENSG00000103148	NA	NA	rs6600233-T	rs6600233	0	6600233	intron_variant	FALSE	0.4573	3e-11	10.522878745280337	NA	0.02437664	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4573	NA	0.02437664
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	16p13.3	16	165107	HBZP1	HBZP1, HBM	NA	NA	ENSG00000206178, ENSG00000206177	NA	NA	rs7194649-A	rs7194649	0	7194649	non_coding_transcript_exon_variant	FALSE	0.1058	3e-27	26.522878745280337	NA	0.06471012	[0.053-0.076] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1058	NA	0.06471012
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	16p13.3	16	168533	HBA2, Z84721.4	HBM - HBAP1	ENSG00000206177	ENSG00000225323	NA	1769	146	rs1203833-C	rs1203833	0	1203833	intergenic_variant	TRUE	0.1788	2e-24	23.69897000433602	NA	0.04805413	[0.039-0.057] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1788	NA	0.04805413
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	16q22.1	16	68796765	CDH1	CDH1	NA	NA	ENSG00000039068	NA	NA	rs71382075-GA	rs71382075	1	35199353	intron_variant	FALSE	0.3078	6e-17	16.221848749616356	NA	0.03264661	[0.025-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3078	NA	0.03264661
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	16q24.1	16	84747007	USP10	USP10	NA	NA	ENSG00000103194	NA	NA	rs12920732-T	rs12920732	0	12920732	intron_variant	FALSE	0.2204	5e-10	9.301029995663981	NA	0.0268343	[0.018-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2204	NA	0.0268343
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	CTU2	NA	NA	NA	NA	NA	NA	chr16:88781091-C	chr16:88781091	0	NA	NA	TRUE	0.0015	4e-14	13.397940008672037	NA	0.3481255	[0.26-0.44] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0015	NA	0.3481255
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	16q24.3	16	88785260	PIEZO1	PIEZO1 - CDT1	ENSG00000103335	ENSG00000167513	NA	40	18529	rs2926772-G	rs2926772	0	2926772	TF_binding_site_variant	TRUE	0.606	5e-9	8.301029995663981	NA	0.02166576	[0.014-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.606	NA	0.02166576
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	16q24.3	16	89873521	TCF25	SPIRE2 - TCF25	ENSG00000204991	ENSG00000141002	NA	2202	49	rs9939914-C	rs9939914	0	9939914	regulatory_region_variant	TRUE	0.2539	8e-12	11.096910013008056	NA	0.02856619	[0.02-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2539	NA	0.02856619
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17p11.2	17	20034096	SPECC1	SPECC1	NA	NA	ENSG00000128487	NA	NA	rs34012755-C	rs34012755	0	34012755	intron_variant	FALSE	0.4077	4e-13	12.397940008672037	NA	0.02670509	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4077	NA	0.02670509
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q11.2	17	28856086	ERAL1	ERAL1	NA	NA	ENSG00000132591	NA	NA	rs9914988-A	rs9914988	0	9914988	intron_variant	FALSE	0.7961	6e-25	24.221848749616356	NA	0.04576578	[0.037-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.7961	NA	0.04576578
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q11.2	17	32792019	MYO1D	MYO1D	NA	NA	ENSG00000176658	NA	NA	rs17780981-G	rs17780981	0	17780981	intron_variant	FALSE	0.1894	7e-15	14.154901959985743	NA	0.03559247	[0.027-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1894	NA	0.03559247
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q12	17	35553481	RP11-1094M14.12	SLFN14	NA	NA	ENSG00000236320	NA	NA	rs36064799-CA	rs36064799	0	36064799	non_coding_transcript_exon_variant	FALSE	0.0462	1e-15	15	NA	0.06822157	[0.051-0.085] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0462	NA	0.06822157
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q12	17	35619088	AP2B1	AP2B1	NA	NA	ENSG00000006125	NA	NA	rs225245-G	rs225245	0	225245	intron_variant	FALSE	0.4562	6e-42	41.221848749616356	NA	0.0488401	[0.042-0.056] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4562	NA	0.0488401
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q12	17	35649600	AP2B1	AP2B1	NA	NA	ENSG00000006125	NA	NA	rs9915021-T	rs9915021	0	9915021	intron_variant	FALSE	0.064	3e-29	28.522878745280337	NA	0.0822496	[0.068-0.097] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.064	NA	0.0822496
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q21.2	17	41921971	ACLY	ACLY	NA	NA	ENSG00000131473	NA	NA	rs4796622-G	rs4796622	0	4796622	intron_variant	FALSE	0.9165	1e-17	17	NA	0.05538642	[0.043-0.068] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.9165	NA	0.05538642
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q21.31	17	44201473	CTB-175E5.7	ATXN7L3-AS1	NA	NA	ENSG00000267394	NA	NA	rs9303601-G	rs9303601	0	9303601	intron_variant	FALSE	0.8624	4e-11	10.397940008672037	NA	0.03444662	[0.024-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.86240000000000006	NA	0.03444662
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	KANSL1	NA	NA	NA	NA	NA	NA	chr17:44217895-CA	chr17:44217895	0	NA	NA	TRUE	0.2069	3e-11	10.522878745280337	NA	0.03176167	[0.022-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2069	NA	0.03176167
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q25.1	17	76387027	SPHK1	SPHK1	NA	NA	ENSG00000176170	NA	NA	rs549579958-C	rs549579958	0	549579958	frameshift_variant	FALSE	0.004	9e-29	28.045757490560675	NA	0.3263584	[0.27-0.38] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.004	NA	0.3263584
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	17q25.1	17	76464800	AANAT	AANAT	NA	NA	ENSG00000129673	NA	NA	rs386386678-ATT	rs386386678	1	56837304	intron_variant	FALSE	0.6703	2e-21	20.69897000433602	NA	0.0371145	[0.029-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.6703	NA	0.0371145
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	11p15.4	11	8825494	ST5	DENND2B	NA	NA	ENSG00000166444	NA	NA	rs10769966-A	rs10769966	0	10769966	intron_variant	FALSE	0.4939	2e-15	14.698970004336019	NA	0.02851905	[0.021-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4939	NA	0.02851905
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	11p15.4	11	9748015	SWAP70	SWAP70	NA	NA	ENSG00000133789	NA	NA	rs415895-G	rs415895	0	415895	stop_gained	FALSE	0.6464	4e-9	8.397940008672037	NA	0.02200319	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.6464	NA	0.02200319
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	11p15.2	11	16737518	SOX6, C11orf58	SOX6, C11orf58	NA	NA	ENSG00000110693, ENSG00000110696	NA	NA	rs376898975-TA	rs376898975	1	60393896	intron_variant	FALSE	0.4053	7e-15	14.154901959985743	NA	0.02887673	[0.022-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4053	NA	0.02887673
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	CD82	NA	NA	NA	NA	NA	NA	chr11:44581593-C	chr11:44581593	0	NA	NA	TRUE	0.3933	7e-11	10.154901959985743	NA	0.02408962	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3933	NA	0.02408962
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	11q13.1	11	64207494	FERMT3	FERMT3	NA	NA	ENSG00000149781	NA	NA	rs149000560-A	rs149000560	0	149000560	missense_variant	FALSE	0.0082	5e-17	16.30102999566398	NA	0.170717	[0.13-0.21] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0082	NA	0.170717
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	11q13.1	11	64256584	PLCB3	PLCB3	NA	NA	ENSG00000149782	NA	NA	rs588177-A	rs588177	0	588177	intron_variant	FALSE	0.6878	1e-9	9	NA	0.0234532	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.6878	NA	0.0234532
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	11q13.1	11	65706327	intergenic	RN7SL309P - KAT5	ENSG00000239356	ENSG00000172977	NA	10490	5669	rs10750766-A	rs10750766	0	10750766	regulatory_region_variant	TRUE	0.7085	1e-13	13	NA	0.02931235	[0.022-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.7085	NA	0.02931235
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	11q21	11	95575690	intergenic	SESN3 - FAM76B	ENSG00000149212	ENSG00000077458	NA	343149	193263	rs11021221-A	rs11021221	0	11021221	intron_variant	TRUE	0.1691	3e-17	16.522878745280337	NA	0.0404898	[0.031-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1691	NA	0.0404898
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	11q22.1	11	100767524	ARHGAP42	ARHGAP42	NA	NA	ENSG00000165895	NA	NA	rs667575-A	rs667575	0	667575	intron_variant	FALSE	0.7276	2e-14	13.698970004336019	NA	0.03103915	[0.023-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.7276	NA	0.03103915
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	11q23.3	11	116778201	ZNF259	ZPR1	NA	NA	ENSG00000109917	NA	NA	rs964184-C	rs964184	0	964184	3_prime_UTR_variant	FALSE	0.8665	3e-11	10.522878745280337	NA	0.03503236	[0.025-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.8665	NA	0.03503236
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	11q23.3	11	119260224	CBL	CBL	NA	NA	ENSG00000110395	NA	NA	rs68034047-C	rs68034047	0	68034047	intron_variant	FALSE	0.2235	4e-10	9.397940008672037	NA	0.02713001	[0.019-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2235	NA	0.02713001
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	12p13.31	12	8698552	RIMKLB	RIMKLB	NA	NA	ENSG00000166532	NA	NA	rs112056543-A	rs112056543	0	112056543	intron_variant	FALSE	0.2786	5e-15	14.301029995663981	NA	0.03143039	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2786	NA	0.03143039
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	12q13.3	12	56684836	PTGES3	PTGES3	NA	NA	ENSG00000110958	NA	NA	rs2290893-G	rs2290893	0	2290893	intron_variant	FALSE	0.6446	4e-9	8.397940008672037	NA	0.02208416	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.6446	NA	0.02208416
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	12q22	12	95464207	RP11-490G8.1	RNU6-735P - METAP2	ENSG00000222544	ENSG00000111142	NA	25364	9313	rs72449396-T	rs72449396	0	72449396	regulatory_region_variant	TRUE	0.3368	1e-21	21	NA	0.03629159	[0.029-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3368	NA	0.03629159
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	12q24.12	12	111466567	ATXN2	ATXN2	NA	NA	ENSG00000204842	NA	NA	rs4766578-A	rs4766578	0	4766578	intron_variant	FALSE	0.5028	2e-60	59.69897000433602	NA	0.0586027	[0.052-0.066] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5028	NA	0.0586027
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	12q24.13	12	112541231	intergenic	PTPN11 - RPH3A	ENSG00000179295	ENSG00000089169	NA	31313	29149	rs35675096-A	rs35675096	0	35675096	intergenic_variant	TRUE	0.0895	3e-42	41.52287874528034	NA	0.08720945	[0.075-0.1] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0895	NA	0.08720945
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	12q24.31	12	120472201	DYNLL1	DYNLL1	NA	NA	ENSG00000088986	NA	NA	rs4767902-T	rs4767902	0	4767902	intron_variant	FALSE	0.3319	2e-83	82.69897000433602	NA	0.07385731	[0.066-0.081] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3319	NA	0.07385731
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	12q24.31	12	120482327	DYNLL1	DYNLL1	NA	NA	ENSG00000088986	NA	NA	rs11352199-A	rs11352199	0	11352199	intron_variant	FALSE	0.4465	2e-79	78.69897000433602	NA	0.06871397	[0.062-0.076] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4465	NA	0.06871397
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	13q14.12	13	45014070	RP11-321C24.1, GPALPP1	GPALPP1	NA	NA	ENSG00000133114	NA	NA	rs73181516-G	rs73181516	0	73181516	intron_variant	FALSE	0.0748	8e-11	10.096910013008056	NA	0.04460671	[0.031-0.058] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0748	NA	0.04460671
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	13q14.3	13	50814824	DLEU7-AS1, DLEU7	DLEU7, DLEU1	NA	NA	ENSG00000186047, ENSG00000176124	NA	NA	rs9535495-T	rs9535495	0	9535495	intron_variant	FALSE	0.5569	1e-13	13	NA	0.02694815	[0.02-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5569	NA	0.02694815
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	14q11.2	14	23030112	PSMB5	PSMB5	NA	NA	ENSG00000100804	NA	NA	rs113525195-A	rs113525195	0	113525195	intron_variant	FALSE	0.2766	3e-26	25.522878745280337	NA	0.04259004	[0.035-0.05] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2766	NA	0.04259004
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	14q13.2	14	34816956	BAZ1A	BAZ1A	NA	NA	ENSG00000198604	NA	NA	rs17592366-A	rs17592366	0	17592366	intron_variant	FALSE	0.0998	2e-21	20.69897000433602	NA	0.05674984	[0.045-0.068] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0998	NA	0.05674984
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	SPTB	NA	NA	NA	NA	NA	NA	chr11:44581593-C	chr14:65281472	0	NA	NA	TRUE	0.3104	1e-11	11	NA	0.02638938	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3104	NA	0.02638938
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	14q24.1	14	67416907	PLEK2	PLEK2 - MIR5694	ENSG00000100558	ENSG00000265993	NA	4740	24948	rs17248895-C	rs17248895	0	17248895	regulatory_region_variant	TRUE	0.1031	5e-12	11.301029995663981	NA	0.04076049	[0.029-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1031	NA	0.04076049
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	14q24.3	14	73741643	ELMSAN1	MIDEAS	NA	NA	ENSG00000156030	NA	NA	rs533217053-C	rs533217053	0	533217053	intron_variant	FALSE	0.0071	2e-21	20.69897000433602	NA	0.206528	[0.16-0.25] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0071	NA	0.206528
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8p11.21	8	41691973	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs72638986-A	rs72638986	0	72638986	intron_variant	FALSE	0.0338	3e-18	17.522878745280337	NA	0.08651011	[0.067-0.106] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0338	NA	0.08651011
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8p11.21	8	41732218	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs149489081-G	rs149489081	0	149489081	intron_variant	FALSE	0.0117	9e-10	9.045757490560675	NA	0.1079376	[0.073-0.142] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0117	NA	0.1079376
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8p11.21	8	41772929	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs4737010-A	rs4737010	0	4737010	intron_variant	FALSE	0.2282	8e-28	27.096910013008056	NA	0.04696383	[0.039-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2282	NA	0.04696383
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8q21.2	8	85361801	CA1	CA1	NA	NA	ENSG00000133742	NA	NA	rs6997458-G	rs6997458	0	6997458	intron_variant	FALSE	0.5709	2e-10	9.698970004336019	NA	0.02303281	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5709	NA	0.02303281
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8q23.1	8	107388433	ANGPT1	ANGPT1	NA	NA	ENSG00000154188	NA	NA	rs145224266-A	rs145224266	0	145224266	intron_variant	FALSE	0.5874	2e-9	8.698970004336019	NA	0.02189125	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5874	NA	0.02189125
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8q23.3	8	115655407	TRPS1	TRPS1	NA	NA	ENSG00000104447	NA	NA	rs2737265-G	rs2737265	0	2737265	intron_variant	FALSE	0.2824	3e-24	23.522878745280337	NA	0.04060887	[0.033-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2824	NA	0.04060887
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8q24.13	8	125494452	RP11-136O12.2	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	56049	365269	rs112875651-A	rs112875651	0	112875651	intron_variant	TRUE	0.3925	1e-11	11	NA	0.02517532	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3925	NA	0.02517532
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	8q24.3	8	141218810	SLC45A4	SLC45A4	NA	NA	ENSG00000022567	NA	NA	rs753778-A	rs753778	0	753778	missense_variant	FALSE	0.2935	1e-10	10	NA	0.02530238	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2935	NA	0.02530238
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	9p24.1	9	4855858	RCL1	RCL1	NA	NA	ENSG00000120158	NA	NA	rs7853365-C	rs7853365	0	7853365	intron_variant	FALSE	0.2073	5e-17	16.30102999566398	NA	0.03710078	[0.028-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2073	NA	0.03710078
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	9p22.2	9	16901230	intergenic	BNC2 - NA	ENSG00000173068	NA	NA	30387	NA	rs13300853-T	rs13300853	0	13300853	intergenic_variant	TRUE	0.3464	1e-9	9	NA	0.02279458	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3464	NA	0.02279458
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	9p13.3	9	34057211	intergenic	RN7SKP114 - DCAF12	ENSG00000222259	ENSG00000198876	NA	6967	29176	rs34756862-T	rs34756862	0	34756862	intergenic_variant	TRUE	0.3611	2e-13	12.698970004336019	NA	0.02819336	[0.021-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3611	NA	0.02819336
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	9q21.13	9	74364687	intergenic	NA	NA	NA	NA	NA	NA	rs140297755-CCAA	rs140297755	0	140297755	intergenic_variant	TRUE	0.3269	2e-11	10.698970004336019	NA	0.02596015	[0.018-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3269	NA	0.02596015
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	9q22.1	9	88783043	intergenic	MIR4289 - NA	ENSG00000265873	NA	NA	37138	NA	rs73652622-G	rs73652622	0	73652622	intron_variant	TRUE	0.0641	2e-10	9.698970004336019	NA	0.04696628	[0.032-0.061] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0641	NA	0.04696628
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	9q22.2	9	89416446	SEMA4D	SEMA4D	NA	NA	ENSG00000187764	NA	NA	rs58785784-C	rs58785784	0	58785784	intron_variant	FALSE	0.2855	7e-10	9.154901959985743	NA	0.02445739	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2855	NA	0.02445739
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	9q34.13	9	132986603	GFI1B	GFI1B	NA	NA	ENSG00000165702	NA	NA	rs61469632-C	rs61469632	0	61469632	intron_variant	FALSE	0.0622	1e-22	22	NA	0.07338335	[0.059-0.088] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0622	NA	0.07338335
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	9q34.2	9	134085798	intergenic	ARF4P1 - WDR5-DT	ENSG00000271525	ENSG00000273249	NA	6354	46444	rs35259020-T	rs35259020	0	35259020	intergenic_variant	TRUE	0.1638	5e-12	11.301029995663981	NA	0.03363898	[0.024-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1638	NA	0.03363898
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	9q34.2	9	134226324	intergenic	RNU6ATAC - LINC02247	ENSG00000221676	ENSG00000223729	NA	61760	67607	rs1475718-A	rs1475718	0	1475718	TF_binding_site_variant	TRUE	0.4444	1e-19	19	NA	0.0332296	[0.026-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4444	NA	0.0332296
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	9q34.3	9	137205865	NDOR1	NDOR1	NA	NA	ENSG00000188566	NA	NA	rs113809617-G	rs113809617	0	113809617	missense_variant	FALSE	0.1335	2e-16	15.698970004336019	NA	0.04466548	[0.034-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1335	NA	0.04466548
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	10p12.1	10	24929314	PRTFDC1	PRTFDC1	NA	NA	ENSG00000099256	NA	NA	rs10828725-T	rs10828725	0	10828725	intron_variant	FALSE	0.3704	6e-202	201.22184874961636	NA	0.1124622	[0.11-0.12] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3704	NA	0.1124622
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	10q11.21	10	44904499	RP11-285G1.2, TMEM72-AS1	TMEM72-AS1	NA	NA	ENSG00000224812	NA	NA	rs397731217-TA	rs397731217	1	5784657	intron_variant	FALSE	0.5801	1e-10	10	NA	0.02395703	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5801	NA	0.02395703
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	10q11.21	10	45453806	RP11-67C2.2	ALOX5 - MARCHF8	ENSG00000275565	ENSG00000278545	NA	7687	779	rs76493570-A	rs76493570	0	76493570	regulatory_region_variant	TRUE	0.07	1e-32	32	NA	0.08362033	[0.07-0.097] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.07	NA	0.08362033
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	10q11.21	10	45458319	NR	MARCHF8, MARCHF8	NA	NA	ENSG00000165406, ENSG00000278545	NA	NA	rs7908745-G	rs7908745	0	7908745	missense_variant	FALSE	0.3143	4e-50	49.39794000867204	NA	0.0573338	[0.05-0.065] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3143	NA	0.0573338
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	10q22.1	10	69334748	HK1	HK1	NA	NA	ENSG00000156515	NA	NA	rs17476364-C	rs17476364	0	17476364	intron_variant	FALSE	0.1104	3e-53	52.52287874528034	NA	0.08805049	[0.077-0.099] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1104	NA	0.08805049
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	10q22.3	10	79357481	PPIF	PPIF - ZCCHC24	ENSG00000108179	ENSG00000165424	NA	2147	24844	rs7917610-C	rs7917610	0	7917610	intergenic_variant	TRUE	0.4628	6e-11	10.221848749616356	NA	0.02356267	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4628	NA	0.02356267
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	10q24.33	10	103107201	NT5C2	NT5C2	NA	NA	ENSG00000076685	NA	NA	rs7896547-G	rs7896547	0	7896547	intron_variant	FALSE	0.3905	4e-42	41.39794000867204	NA	0.04985184	[0.043-0.057] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3905	NA	0.04985184
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	2p21	2	41954539	C2orf91, PKDCC	C2orf91	NA	NA	ENSG00000205086	NA	NA	rs6740960-T	rs6740960	0	6740960	intron_variant	FALSE	NA	2e-10	9.698970004336019	(EA)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	2p21	2	41954539	C2orf91, PKDCC	C2orf91	NA	NA	ENSG00000205086	NA	NA	rs6740960-T	rs6740960	0	6740960	intron_variant	FALSE	NA	6e-13	12.221848749616356	(All)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	2q35	2	219743055	NR	LINC02832 - NA	ENSG00000227308	NA	NA	5118	NA	rs112800917-?	rs112800917	1	67333116	intergenic_variant	TRUE	NA	9e-7	6.045757490560675	(All)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	5q33.3	5	158560211	NR	NA	NA	NA	NA	NA	NA	rs2963482-?	rs2963482	0	2963482	intron_variant	TRUE	NA	8e-6	5.096910013008056	(EA)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	6p24.3	6	10390871	NR	NA - TFAP2A	NA	ENSG00000137203	NA	NA	2315	rs151137431-?	rs151137431	0	151137431	intergenic_variant	TRUE	NA	9e-6	5.045757490560675	(EA)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	6p21.33	6	31172964	NR	POU5F1, POU5F1, POU5F1, POU5F1, POU5F1, POU5F1, POU5F1	NA	NA	ENSG00000204531, ENSG00000233911, ENSG00000229094, ENSG00000230336, ENSG00000206454, ENSG00000237582, ENSG00000235068	NA	NA	rs1265158-?	rs1265158	0	1265158	intron_variant	FALSE	NA	5e-6	5.301029995663981	(EA)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	6p21.33	6	31172964	NR	POU5F1, POU5F1, POU5F1, POU5F1, POU5F1, POU5F1, POU5F1	NA	NA	ENSG00000204531, ENSG00000233911, ENSG00000229094, ENSG00000230336, ENSG00000206454, ENSG00000237582, ENSG00000235068	NA	NA	rs1265158-?	rs1265158	0	1265158	intron_variant	FALSE	NA	3e-6	5.522878745280337	(All)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	8q21.13	8	76593073	NR	ZFHX4-AS1	NA	NA	ENSG00000253661	NA	NA	rs10808812-?	rs10808812	0	10808812	intron_variant	FALSE	NA	1e-6	6	(All)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	9q22.2	9	89421512	NR	SEMA4D	NA	NA	ENSG00000187764	NA	NA	rs4132699-?	rs4132699	0	4132699	intron_variant	FALSE	NA	9e-8	7.045757490560675	(All)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	9q22.2	9	89595154	NR	SEMA4D - GADD45G	ENSG00000187764	ENSG00000130222	NA	97024	9858	rs12375983-?	rs12375983	0	12375983	intron_variant	TRUE	NA	1e-6	6	(EA)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	14q22.1	14	51389391	RP11-255G12.2, TMX1, FRMD6, LINC00640	LINC00640 - LINC02310	ENSG00000258479	ENSG00000258808	NA	23834	2737	rs4901118-A	rs4901118	0	4901118	intergenic_variant	TRUE	NA	2e-7	6.698970004336019	(EA)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	14q22.1	14	51389391	RP11-255G12.2, TMX1, FRMD6, LINC00640	LINC00640 - LINC02310	ENSG00000258479	ENSG00000258808	NA	23834	2737	rs4901118-A	rs4901118	0	4901118	intergenic_variant	TRUE	NA	7e-10	9.154901959985743	(All)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28087736	Ludwig KU	2017-01-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.	Nonsyndromic cleft lip with or without cleft palate	399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios	224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls	19p13.3	19	2050824	MKNK2	MKNK2	NA	NA	ENSG00000099875	NA	NA	rs3746101-T	rs3746101	0	3746101	stop_gained	FALSE	NA	2e-8	7.698970004336019	(EA)	NA	NA	NR [8012124] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004088	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	18q11.2	18	23469770	RIOK3	RIOK3	NA	NA	ENSG00000101782	NA	NA	rs140271614-A	rs140271614	0	140271614	intron_variant	FALSE	0.0065	8e-14	13.096910013008056	NA	0.1838517	[0.14-0.23] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0065	NA	0.1838517
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1q23.1	1	158668470	SPTA1	SPTA1	NA	NA	ENSG00000163554	NA	NA	rs140446749-A	rs140446749	0	140446749	intron_variant	FALSE	0.0115	3e-47	46.52287874528034	NA	0.2438309	[0.21-0.28] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0115	NA	0.2438309
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1q22	1	155301643	PKLR	PKLR - FDPS	ENSG00000143627	ENSG00000160752	NA	205	7105	rs141119689-T	rs141119689	0	141119689	intergenic_variant	TRUE	0.069	1e-23	23	NA	0.07211229	[0.058-0.086] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.069	NA	0.07211229
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1q32.1	1	199041592	RP11-16L9.4	LINC01221	NA	NA	ENSG00000235492	NA	NA	rs1434282-T	rs1434282	0	1434282	non_coding_transcript_exon_variant	FALSE	0.7266	8e-23	22.096910013008056	NA	0.03986365	[0.032-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.7266	NA	0.03986365
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	17q25.3	17	78138386	TMC8	TMC8	NA	NA	ENSG00000167895	NA	NA	rs144120533-T	rs144120533	0	144120533	missense_variant	FALSE	0.0031	2e-10	9.698970004336019	NA	0.218292	[0.15-0.29] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0031	NA	0.218292
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1q25.3	1	183878145	RGL1	RGL1	NA	NA	ENSG00000143344	NA	NA	rs145589976-T	rs145589976	1	56816532	intron_variant	FALSE	0.4471	1e-11	11	NA	0.0245111	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4471	NA	0.0245111
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	20q13.2	20	53613492	AC005808.3	ZNF217 - RNU7-14P	ENSG00000171940	ENSG00000238468	NA	3585	55205	rs145910606-T	rs145910606	0	145910606	intron_variant	TRUE	0.0174	1e-19	19	NA	0.1328789	[0.1-0.16] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0174	NA	0.1328789
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	17p11.2	17	19994250	intergenic	AKAP10 - SPECC1-DT	ENSG00000108599	ENSG00000261033	NA	15907	13801	rs146563863-C	rs146563863	0	146563863	intergenic_variant	TRUE	0.3469	4e-11	10.397940008672037	NA	0.02493103	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.3469	NA	0.02493103
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6p22.3	6	16285830	GMPR	GMPR	NA	NA	ENSG00000137198	NA	NA	rs146771786-A	rs146771786	0	146771786	missense_variant	FALSE	0.0014	1e-10	10	NA	0.344219	[0.24-0.45] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0014	NA	0.344219
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	5q31.1	5	133091160	HSPA4	HSPA4	NA	NA	ENSG00000170606	NA	NA	rs147133967-G	rs147133967	0	147133967	splice_region_variant	FALSE	0.0928	6e-9	8.221848749616356	NA	0.03596435	[0.024-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0928	NA	0.03596435
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6p21.33	6	30785151	HCG20	HCG20, HCG20, HCG20, HCG20, HCG20, HCG20	NA	NA	ENSG00000224133, ENSG00000238216, ENSG00000224641, ENSG00000228022, ENSG00000224923, ENSG00000228762	NA	NA	rs147206302-T	rs147206302	0	147206302	intron_variant	FALSE	0.0032	7e-9	8.154901959985743	NA	0.1843882	[0.12-0.25] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0032	NA	0.1843882
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6q23.2	6	132499141	STX7	STX7	NA	NA	ENSG00000079950	NA	NA	rs147324647-CCT	rs147324647	0	147324647	intron_variant	FALSE	0.4551	3e-9	8.522878745280337	NA	0.02161217	[0.014-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4551	NA	0.02161217
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	9q34.2	9	134226324	intergenic	RNU6ATAC - LINC02247	ENSG00000221676	ENSG00000223729	NA	61760	67607	rs1475718-A	rs1475718	0	1475718	TF_binding_site_variant	TRUE	0.4444	2e-11	10.698970004336019	NA	0.02464611	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4444	NA	0.02464611
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	2p23.3	2	23987207	UBXN2A	UBXN2A	NA	NA	ENSG00000173960	NA	NA	rs147649347-G	rs147649347	0	147649347	intron_variant	FALSE	0.1361	3e-44	43.52287874528034	NA	0.07288792	[0.063-0.083] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1361	NA	0.07288792
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6p22.1	6	30159782	TRIM10	TRIM10, TRIM10, TRIM10, TRIM10, TRIM10, TRIM10, TRIM10, TRIM10	NA	NA	ENSG00000204613, ENSG00000137394, ENSG00000229381, ENSG00000237703, ENSG00000237192, ENSG00000227472, ENSG00000229346, ENSG00000235025	NA	NA	rs148280884-CAT	rs148280884	0	148280884	intron_variant	FALSE	0.0122	4e-25	24.397940008672037	NA	0.1718773	[0.14-0.2] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0122	NA	0.1718773
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	8p11.21	8	41732218	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs149489081-G	rs149489081	0	149489081	intron_variant	FALSE	0.0117	2e-20	19.69897000433602	NA	0.1637982	[0.13-0.2] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0117	NA	0.1637982
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	5q11.2	5	52801055	PELO	PELO, ITGA1	NA	NA	ENSG00000152684, ENSG00000213949	NA	NA	rs1499280-A	rs1499280	0	1499280	missense_variant	FALSE	0.9186	5e-33	32.30102999566398	NA	0.07831162	[0.065-0.091] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.9186	NA	0.07831162
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	9q34.13	9	132989126	GFI1B	GFI1B	NA	NA	ENSG00000165702	NA	NA	rs150813342-T	rs150813342	0	150813342	synonymous_variant	FALSE	0.0085	2e-13	12.698970004336019	NA	0.1490594	[0.11-0.19] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0085	NA	0.1490594
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	8q21.2	8	85356084	CA1	CA1	NA	NA	ENSG00000133742	NA	NA	rs1532423-G	rs1532423	0	1532423	intron_variant	FALSE	0.5712	1e-9	9	NA	0.02212958	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.5712	NA	0.02212958
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	19q13.42	19	55014977	GP6	GP6-AS1, GP6, GP6, GP6, GP6, GP6, GP6, GP6, GP6, GP6, GP6	NA	NA	ENSG00000267265, ENSG00000275633, ENSG00000278316, ENSG00000275931, ENSG00000277439, ENSG00000278670, ENSG00000274050, ENSG00000276065, ENSG00000276211, ENSG00000274566, ENSG00000088053	NA	NA	rs1671152-G	rs1671152	0	1671152	missense_variant	FALSE	0.84	3e-9	8.522878745280337	NA	0.0293111	[0.02-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.84	NA	0.0293111
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	19p13.3	19	913048	R3HDM4	R3HDM4	NA	NA	ENSG00000198858	NA	NA	rs1683587-C	rs1683587	0	1683587	intron_variant	FALSE	0.5151	9e-31	30.045757490560675	NA	0.04448547	[0.037-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.5151	NA	0.04448547
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	19q13.33	19	48872268	PLEKHA4, PPP1R15A	PLEKHA4 - PPP1R15A	ENSG00000105559	ENSG00000087074	NA	3651	153	rs17272694-T	rs17272694	0	17272694	TF_binding_site_variant	TRUE	0.0296	3e-15	14.522878745280337	NA	0.08419195	[0.063-0.105] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0296	NA	0.08419195
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	14q23.3	14	64813358	SPTB	SPTB	NA	NA	ENSG00000070182	NA	NA	rs1741464-A	rs1741464	0	1741464	intron_variant	FALSE	0.2895	3e-21	20.522878745280337	NA	0.03759359	[0.03-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2895	NA	0.03759359
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	5q15	5	95827733	GLRX	RHOBTB3 - GGCTP1	ENSG00000164292	ENSG00000251000	NA	3350	6691	rs17462893-G	rs17462893	0	17462893	intergenic_variant	TRUE	0.1017	4e-31	30.397940008672037	NA	0.06894116	[0.057-0.081] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1017	NA	0.06894116
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	10q22.1	10	69334748	HK1	HK1	NA	NA	ENSG00000156515	NA	NA	rs17476364-C	rs17476364	0	17476364	intron_variant	FALSE	0.1104	3e-72	71.52287874528034	NA	0.1032995	[0.092-0.115] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1104	NA	0.1032995
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p34.3	1	37683093	NR	C1orf109; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs684260-G; rs497705-C; rs11264091-G; rs3790623-A; rs658024-A; rs510208-T; rs11264087-C; rs661460-A; rs768659-A; rs12139097-T; rs12119598-C; rs10908369-G; rs589927-G; rs3762352-C; rs557897-G; rs507667-A	rs684260; rs497705; rs11264091; rs3790623; rs658024; rs510208; rs11264087; rs661460; rs768659; rs12139097; rs12119598; rs10908369; rs589927; rs3762352; rs557897; rs507667	0	NA	3_prime_UTR_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; 3_prime_UTR_variant; intron_variant	NA	0.276	9e-15	14.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.276	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p34.2	1	41771622	NR	HIVEP3; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2013105-A; rs765040-T; rs7535437-A; rs349430-T; rs393950-G	rs2013105; rs765040; rs7535437; rs349430; rs393950	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.248	4e-11	10.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.248	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p34.1	1	45001255	NR	MRPS17P1 - HECTD3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs6666806-C; rs13948-T; rs7535347-C; rs2236576-A; rs7541207-C; rs7528534-C; rs6678726-G; rs6671633-A	rs6666806; rs13948; rs7535347; rs2236576; rs7541207; rs7528534; rs6678726; rs6671633	0	NA	TF_binding_site_variant; non_coding_transcript_exon_variant; regulatory_region_variant; 5_prime_UTR_variant; synonymous_variant; intron_variant; intron_variant; intron_variant	NA	0.0	7e-19	18.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q11.2	17	27692342	NR	CPDP1 - LGALS9DP; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11654271-T; rs7210647-C; rs4796018-A; rs10438809-G; rs9891469-G; rs9897417-G; rs4795915-G; rs6505439-G; rs12948602-A; rs4795911-T; rs7207044-A; rs9898422-G; rs9913854-G; rs9303680-C; rs9901734-C; rs4796017-G; rs8065793-T	rs11654271; rs7210647; rs4796018; rs10438809; rs9891469; rs9897417; rs4795915; rs6505439; rs12948602; rs4795911; rs7207044; rs9898422; rs9913854; rs9303680; rs9901734; rs4796017; rs8065793	0	NA	intergenic_variant; regulatory_region_variant; intron_variant; intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; regulatory_region_variant; regulatory_region_variant; intergenic_variant; intron_variant; intergenic_variant; intergenic_variant; intergenic_variant; intron_variant; intron_variant; intron_variant	NA	0.019	8e-9	8.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.019	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q11.2	17	31516237	NR	RAB11FIP4; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs9901334-T; rs9910757-A; rs882361-T; rs882360-T	rs9901334; rs9910757; rs882361; rs882360	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.172	2e-7	6.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.172	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q11.2	17	31516237	NR	RAB11FIP4; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs9901334-T; rs9910757-A; rs882361-T; rs882360-G	rs9901334; rs9910757; rs882361; rs882360	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.106	5e-7	6.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.106	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q11.2	17	32551730	NR	MYO1D; No mapped genes	NA	NA	NA	NA	NA	rs9903536-G; rs9904359-A	rs9903536; rs9904359	0	NA	intron_variant; intron_variant	NA	0.0	4e-25	24.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q11.2	17	32551730	NR	MYO1D; No mapped genes	NA	NA	NA	NA	NA	rs9903536-G; rs9904359-G	rs9903536; rs9904359	0	NA	intron_variant; intron_variant	NA	0.285	1e-12	12	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.285	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q11.2	17	33096813	NR	ASIC2; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4072512-A; rs9892479-G; rs3925478-G; rs17183972-A; rs4795744-C	rs4072512; rs9892479; rs3925478; rs17183972; rs4795744	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	6e-9	8.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q12	17	37095363	NR	ACACA; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12449696-T; rs7215365-C; rs7208415-G; rs9897583-G; rs12450937-T; rs2106772-T; rs1900101-G; rs17573357-A; rs11651239-A	rs12449696; rs7215365; rs7208415; rs9897583; rs12450937; rs2106772; rs1900101; rs17573357; rs11651239	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	8e-11	10.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q12	17	37095363	NR	ACACA; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12449696-C; rs7215365-C; rs7208415-G; rs9897583-G; rs12450937-T; rs2106772-C; rs1900101-G; rs17573357-A; rs11651239-G	rs12449696; rs7215365; rs7208415; rs9897583; rs12450937; rs2106772; rs1900101; rs17573357; rs11651239	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q12	17	39165352	NR	ARL5C; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs16525-T; rs657672-C; rs17633541-C; rs16526-A	rs16525; rs657672; rs17633541; rs16526	0	NA	non_coding_transcript_exon_variant; missense_variant; 3_prime_UTR_variant; non_coding_transcript_exon_variant	NA	0.0	6e-10	9.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q12	17	39165352	NR	ARL5C; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs16525-T; rs657672-T; rs17633541-C; rs16526-A	rs16525; rs657672; rs17633541; rs16526	0	NA	non_coding_transcript_exon_variant; missense_variant; 3_prime_UTR_variant; non_coding_transcript_exon_variant	NA	0.151	3e-8	7.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.151	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q21.2	17	40399305	NR	TOP2A; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs16965748-T; rs16965783-C; rs473198-T; rs1009570-A	rs16965748; rs16965783; rs473198; rs1009570	0	NA	intron_variant; intergenic_variant; TF_binding_site_variant; intergenic_variant	NA	0.003	4e-13	12.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.003	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q21.2	17	40399305	NR	TOP2A; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs16965748-T; rs16965783-C; rs473198-C; rs1009570-A	rs16965748; rs16965783; rs473198; rs1009570	0	NA	intron_variant; intergenic_variant; TF_binding_site_variant; intergenic_variant	NA	0.191	2e-10	9.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.191	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q21.31	17	43550924	NR	DHX8; ETV4; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12603053-T; rs1316956-G; rs7210301-C; rs9748005-G; rs7208294-G; rs11650719-A; rs4792997-C; rs7217897-T; rs3826413-C; rs12941944-G; rs7223638-G; rs1317254-T; rs4793000-T; rs4792900-C	rs12603053; rs1316956; rs7210301; rs9748005; rs7208294; rs11650719; rs4792997; rs7217897; rs3826413; rs12941944; rs7223638; rs1317254; rs4793000; rs4792900	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; 5_prime_UTR_variant	NA	0.188	1e-11	11	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.188	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q21.31	17	43550924	NR	DHX8; ETV4; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12603053-T; rs1316956-G; rs7210301-C; rs9748005-G; rs7208294-G; rs11650719-A; rs4792997-C; rs7217897-T; rs3826413-C; rs12941944-T; rs7223638-G; rs1317254-T; rs4793000-T; rs4792900-C	rs12603053; rs1316956; rs7210301; rs9748005; rs7208294; rs11650719; rs4792997; rs7217897; rs3826413; rs12941944; rs7223638; rs1317254; rs4793000; rs4792900	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; 5_prime_UTR_variant	NA	0.0	4e-11	10.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q21.31	17	44364976	NR	FAM171A2 - RPL7L1P5; No mapped genes	NA	NA	NA	NA	NA	rs708382-C; rs7223967-C	rs708382; rs7223967	0	NA	intergenic_variant; intron_variant	NA	0.382	8e-20	19.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.382	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q21.31	17	44364976	NR	FAM171A2 - RPL7L1P5; No mapped genes	NA	NA	NA	NA	NA	rs708382-T; rs7223967-C	rs708382; rs7223967	0	NA	intergenic_variant; intron_variant	NA	0.576	1e-15	15	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.576	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q21.33	17	50800538	NR	MIR8059 - WFIKKN2; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs16949303-G; rs17564787-G; rs9807047-A; rs2412340-C; rs11079928-C	rs16949303; rs17564787; rs9807047; rs2412340; rs11079928	0	NA	intergenic_variant; regulatory_region_variant; non_coding_transcript_exon_variant; regulatory_region_variant; non_coding_transcript_exon_variant	NA	0.001	8e-18	17.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.001	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q21.33	17	50800538	NR	MIR8059 - WFIKKN2; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs16949303-G; rs17564787-G; rs9807047-G; rs2412340-C; rs11079928-C	rs16949303; rs17564787; rs9807047; rs2412340; rs11079928	0	NA	intergenic_variant; regulatory_region_variant; non_coding_transcript_exon_variant; regulatory_region_variant; non_coding_transcript_exon_variant	NA	0.155	2e-8	7.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.155	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q23.2	17	61489321	NR	TBX4 - N/A; No mapped genes	NA	NA	NA	NA	NA	rs8070051-C; rs744651-T	rs8070051; rs744651	0	NA	intergenic_variant; regulatory_region_variant	NA	0.178	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.178	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q23.2	17	62942684	NR	N/A - MIR633; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs17686634-C; rs8066912-A; rs17686669-G; rs17686684-C; rs4968746-T	rs17686634; rs8066912; rs17686669; rs17686684; rs4968746	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.442	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.442	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	17q24.1	17	65447924	NR	N/A - LINC02563; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs8066556-T; rs9910104-C; rs12603313-T	rs8066556; rs9910104; rs12603313	0	NA	intergenic_variant; intergenic_variant; intergenic_variant	NA	0.773	8e-7	6.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.773	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	14q13.2	14	34816956	BAZ1A	BAZ1A	NA	NA	ENSG00000198604	NA	NA	rs17592366-A	rs17592366	0	17592366	intron_variant	FALSE	0.0998	3e-17	16.522878745280337	NA	0.05055917	[0.039-0.062] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0998	NA	0.05055917
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	20p13	20	4155202	SMOX	SMOX	NA	NA	ENSG00000088826	NA	NA	rs1765003-A	rs1765003	0	1765003	intron_variant	FALSE	0.136	1e-108	108	NA	0.11651	[0.11-0.13] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.136	NA	0.11651
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6p22.2	6	26090951	HFE	HFE	NA	NA	ENSG00000010704	NA	NA	rs1799945-G	rs1799945	0	1799945	missense_variant	FALSE	0.1504	3e-40	39.52287874528034	NA	0.06648829	[0.057-0.076] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1504	NA	0.06648829
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1q23.1	1	158613814	SPTA1	SPTA1	NA	NA	ENSG00000163554	NA	NA	rs201514157-A	rs201514157	0	201514157	missense_variant	FALSE	7.0E-4	5e-16	15.301029995663981	NA	0.6033977	[0.46-0.75] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	7e-4	NA	0.6033977
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1q23.1	1	158617176	SPTA1	SPTA1	NA	NA	ENSG00000163554	NA	NA	rs2022003-T	rs2022003	0	2022003	intron_variant	FALSE	0.2785	1e-151	151	NA	0.1045314	[0.097-0.112] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2785	NA	0.1045314
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6p22.1	6	30153683	TRIM10	TRIM10, TRIM10, TRIM10, TRIM10, TRIM10, TRIM10, TRIM10, TRIM10	NA	NA	ENSG00000204613, ENSG00000137394, ENSG00000229381, ENSG00000237703, ENSG00000237192, ENSG00000227472, ENSG00000229346, ENSG00000235025	NA	NA	rs2022065-T	rs2022065	0	2022065	3_prime_UTR_variant	FALSE	0.2963	3e-25	24.522878745280337	NA	0.04064069	[0.033-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2963	NA	0.04064069
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	20q12	20	39934603	HSPE1P1	HSPE1P1 - LINC01370	ENSG00000234878	ENSG00000237767	NA	1364	69613	rs2145943-G	rs2145943	0	2145943	intergenic_variant	TRUE	0.4077	5e-16	15.301029995663981	NA	0.02980376	[0.023-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4077	NA	0.02980376
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	4q12	4	54542832	intergenic	LINC02283 - LINC02260	ENSG00000248184	ENSG00000250456	NA	186878	60379	rs218265-C	rs218265	0	218265	intergenic_variant	TRUE	0.1572	4e-19	18.397940008672037	NA	0.04472222	[0.035-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1572	NA	0.04472222
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	3q23	3	142558733	ATR	ATR	NA	NA	ENSG00000175054	NA	NA	rs2227930-T	rs2227930	0	2227930	synonymous_variant	FALSE	0.5871	3e-9	8.522878745280337	NA	0.02152074	[0.014-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.5871	NA	0.02152074
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	17q25.1	17	76385474	SPHK1	SPHK1	NA	NA	ENSG00000176170	NA	NA	rs2247856-A	rs2247856	0	2247856	missense_variant	FALSE	0.4666	2e-27	26.69897000433602	NA	0.03891775	[0.032-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4666	NA	0.03891775
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	17q12	17	35619088	AP2B1	AP2B1	NA	NA	ENSG00000006125	NA	NA	rs225245-G	rs225245	0	225245	intron_variant	FALSE	0.4561	1e-130	130	NA	0.08756592	[0.081-0.095] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4561	NA	0.08756592
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	19p13.2	19	10230236	DNMT1, S1PR2	DNMT1, S1PR2	NA	NA	ENSG00000130816, ENSG00000267534	NA	NA	rs2288937-G	rs2288937	0	2288937	intron_variant	FALSE	0.1724	3e-23	22.522878745280337	NA	0.04712367	[0.038-0.056] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1724	NA	0.04712367
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	17q25.3	17	80138078	EIF4A3	EIF4A3	NA	NA	ENSG00000141543	NA	NA	rs2361710-C	rs2361710	0	2361710	intron_variant	FALSE	0.4724	1e-18	18	NA	0.03152986	[0.025-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4724	NA	0.03152986
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	12p13.31	12	8779605	RIMKLB	RIMKLB, A2ML1-AS1	NA	NA	ENSG00000166532, ENSG00000256661	NA	NA	rs2377585-G	rs2377585	0	2377585	non_coding_transcript_exon_variant	FALSE	0.2771	2e-15	14.698970004336019	NA	0.03197319	[0.024-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2771	NA	0.03197319
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	5q11.2	5	54360775	LINC01033	LINC01033	NA	NA	ENSG00000249069	NA	NA	rs2407513-C	rs2407513	0	2407513	intron_variant	FALSE	0.1549	5e-11	10.301029995663981	NA	0.03274671	[0.023-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1549	NA	0.03274671
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6p22.1	6	30393646	intergenic	UBQLN1P1 - MICC	ENSG00000236122	ENSG00000230887	NA	29366	21069	rs2516686-G	rs2516686	0	2516686	intergenic_variant	TRUE	0.1322	1e-13	13	NA	0.03934043	[0.029-0.05] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1322	NA	0.03934043
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	8q23.3	8	115655407	TRPS1	TRPS1	NA	NA	ENSG00000104447	NA	NA	rs2737265-G	rs2737265	0	2737265	intron_variant	FALSE	0.2824	3e-14	13.522878745280337	NA	0.03029951	[0.022-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2824	NA	0.03029951
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	17q25.3	17	78128765	TMC6	TMC6	NA	NA	ENSG00000141524	NA	NA	rs2748425-C	rs2748425	0	2748425	5_prime_UTR_variant	FALSE	0.1905	1e-20	20	NA	0.04295733	[0.034-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1905	NA	0.04295733
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1p36.11	1	25406057	RHCE	RHCE	NA	NA	ENSG00000188672	NA	NA	rs28513325-A	rs28513325	0	28513325	intron_variant	FALSE	0.9705	2e-12	11.698970004336019	NA	0.08774246	[0.063-0.112] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.9705	NA	0.08774246
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	20p13	20	3646342	ATRN	ATRN	NA	NA	ENSG00000088812	NA	NA	rs2853203-A	rs2853203	0	2853203	intron_variant	FALSE	0.3363	5e-11	10.301029995663981	NA	0.02498324	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.3363	NA	0.02498324
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	19q13.12	19	35202217	intergenic	FXYD5 - FAM187B	ENSG00000089327	ENSG00000177558	NA	32336	22583	rs28659908-C	rs28659908	0	28659908	intergenic_variant	TRUE	0.4075	3e-14	13.522878745280337	NA	0.02835117	[0.021-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4075	NA	0.02835117
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	16q24.3	16	88792238	intergenic	PIEZO1 - CDT1	ENSG00000103335	ENSG00000167513	NA	7018	11551	rs2968478-G	rs2968478	0	2968478	intergenic_variant	TRUE	0.5807	8e-21	20.096910013008056	NA	0.03473789	[0.027-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.5807	NA	0.03473789
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	15q25.1	15	78270761	DNAJA4	DNAJA4	NA	NA	ENSG00000140403	NA	NA	rs3169166-C	rs3169166	0	3169166	intron_variant	FALSE	0.4154	3e-15	14.522878745280337	NA	0.02873104	[0.022-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4154	NA	0.02873104
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	13q34	13	112706624	ATP11A	ATP11A	NA	NA	ENSG00000068650	NA	NA	rs34011672-G	rs34011672	0	34011672	intron_variant	FALSE	0.0894	1e-9	9	NA	0.038104	[0.026-0.05] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0894	NA	0.038104
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	7p22.1	7	6014758	AIMP2	AIMP2	NA	NA	ENSG00000106305	NA	NA	rs34097030-A	rs34097030	0	34097030	intron_variant	FALSE	0.2267	3e-12	11.522878745280337	NA	0.02982401	[0.021-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2267	NA	0.02982401
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	22q12.3	22	37074184	TMPRSS6	TMPRSS6	NA	NA	ENSG00000187045	NA	NA	rs2413450-T	rs2413450	0	2413450	intron_variant	FALSE	NR	2e-10	9.698970004336019	(Asian)	0.0019	[0.0013-0.0025] unit decrease	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	0.0019
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	1q23.1	1	158605939	NR	OR10Z1	NA	NA	ENSG00000198967	NA	NA	rs857684-?	rs857684	0	857684	intron_variant	FALSE	NR	2e-12	11.698970004336019	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	1q32.1	1	203685993	NR	ATP2B4	NA	NA	ENSG00000058668	NA	NA	rs7551442-?	rs7551442	0	7551442	intron_variant	FALSE	NR	3e-7	6.522878745280337	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	8p11.21	8	41772887	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs4737009-?	rs4737009	0	4737009	intron_variant	FALSE	NR	3e-10	9.522878745280337	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	16q24.3	16	88787321	NR	PIEZO1 - CDT1	ENSG00000103335	ENSG00000167513	NA	2101	16468	rs837763-?	rs837763	0	837763	intergenic_variant	TRUE	NR	2e-11	10.698970004336019	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	17q21.31	17	44216969	NR	UBTF	NA	NA	ENSG00000108312	NA	NA	rs2269906-?	rs2269906	0	2269906	intron_variant	FALSE	NR	4e-7	6.3979400086720375	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	6p22.2	6	26107235	HFE, HIST1H1T	H4C3 - H1-6	ENSG00000197061	ENSG00000187475	NA	2898	177	rs198846-?	rs198846	0	198846	intergenic_variant	TRUE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	6q23.3	6	135097778	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs7776054-?	rs7776054	0	7776054	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	12q24.12	12	111803962	SH2B3	ALDH2	NA	NA	ENSG00000111275	NA	NA	rs671-?	rs671	0	671	missense_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	16p13.3	16	248589	ITFG3	FAM234A	NA	NA	ENSG00000167930	NA	NA	rs13339636-?	rs13339636	0	13339636	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	22q12.3	22	37074184	TMPRSS6	TMPRSS6	NA	NA	ENSG00000187045	NA	NA	rs2413450-?	rs2413450	0	2413450	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	1q23.1	1	158605939	NR	OR10Z1	NA	NA	ENSG00000198967	NA	NA	rs857684-?	rs857684	0	857684	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	1q32.1	1	203685993	NR	ATP2B4	NA	NA	ENSG00000058668	NA	NA	rs7551442-?	rs7551442	0	7551442	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	6p21.1	6	41937537	CCND3	CCND3	NA	NA	ENSG00000112576	NA	NA	rs3218097-?	rs3218097	0	3218097	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	8p11.21	8	41772887	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs4737009-?	rs4737009	0	4737009	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	16q24.3	16	88787321	NR	PIEZO1 - CDT1	ENSG00000103335	ENSG00000167513	NA	2101	16468	rs837763-?	rs837763	0	837763	intergenic_variant	TRUE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular hemoglobin concentration	up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals.	16,389 European and African American individuals.	17q21.31	17	44216969	NR	UBTF	NA	NA	ENSG00000108312	NA	NA	rs2269906-?	rs2269906	0	2269906	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular hemoglobin concentration	http://www.ebi.ac.uk/efo/EFO_0004528	GCST004007	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Red blood cell count	up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals.	16,389 individuals of European and African American ancestry.	2p21	2	46120467	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs4952800-A	rs4952800	0	4952800	intron_variant	FALSE	NR	1e-6	6	(Asian)	0.0077	[0.0046-0.0108] unit decrease	NR [2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004008	Genome-wide genotyping array	NA	NA	0.0077
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Red blood cell count	up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals.	16,389 individuals of European and African American ancestry.	4q12	4	54528005	KIT	NA - LINC02260	NA	ENSG00000250456	NA	NA	75206	rs218237-T	rs218237	0	218237	intergenic_variant	TRUE	NR	4e-16	15.397940008672037	(Asian)	0.0106	[0.0081-0.0131] unit decrease	NR [2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004008	Genome-wide genotyping array	NA	NA	0.0106
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Red blood cell count	up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals.	16,389 individuals of European and African American ancestry.	6p21.1	6	41957421	CCND3	CCND3	NA	NA	ENSG00000112576	NA	NA	rs9349205-A	rs9349205	0	9349205	intron_variant	FALSE	NR	2e-9	8.698970004336019	(Asian)	0.009	[0.0061-0.0119] unit increase	NR [2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004008	Genome-wide genotyping array	NA	NA	0.009
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Red blood cell count	up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals.	16,389 individuals of European and African American ancestry.	6q21	6	109311596	CD164	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs9400273-A	rs9400273	0	9400273	intron_variant	FALSE	NR	2e-7	6.698970004336019	(Asian)	0.01	[0.0063-0.0137] unit increase	NR [2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004008	Genome-wide genotyping array	NA	NA	0.01
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Red blood cell count	up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals.	16,389 individuals of European and African American ancestry.	9q34.2	9	133278724	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	2700	23746	rs579459-T	rs579459	0	579459	intergenic_variant	TRUE	NR	4e-11	10.397940008672037	(Asian)	0.0086	[0.0061-0.0111] unit increase	NR [2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004008	Genome-wide genotyping array	NA	NA	0.0086
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Red blood cell count	up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals.	16,389 individuals of European and African American ancestry.	12p13.32	12	4225129	CCND2	HSPA8P5 - CCND2-AS1	ENSG00000256356	ENSG00000255920	NA	125610	22852	rs7309743-A	rs7309743	0	7309743	intergenic_variant	TRUE	NR	1e-7	7	(Asian)	0.0066	[0.0042-0.009] unit increase	NR [2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004008	Genome-wide genotyping array	NA	NA	0.0066
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Red blood cell count	up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals.	16,389 individuals of European and African American ancestry.	4q12	4	54528857	KIT	NA - LINC02260	NA	ENSG00000250456	NA	NA	74354	rs218238-?	rs218238	0	218238	intergenic_variant	TRUE	NR	2e-28	27.69897000433602	NA	NA	NA	NR [2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004008	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Red blood cell count	up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals.	16,389 individuals of European and African American ancestry.	6q23.3	6	135182647	HBS1L	MYB	NA	NA	ENSG00000118513	NA	NA	rs210962-?	rs210962	0	210962	intron_variant	FALSE	NR	5e-16	15.301029995663981	NA	NA	NA	NR [2500000] (imputed)	N	erythrocyte count	http://www.ebi.ac.uk/efo/EFO_0004305	GCST004008	Genome-wide genotyping array	NA	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	8q24.3	8	142979538	RP11-273G15.2	CYP11B2 - LY6E-DT	ENSG00000179142	ENSG00000247317	NA	61695	2200	rs62524579-A	rs62524579	0	62524579	intergenic_variant	TRUE	0.53	4e-9	8.397940008672037	NA	0.175	[0.12-0.23] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.53	NA	0.175
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	9p21.3	9	21801531	MTAP	NA - MTAP	NA	ENSG00000099810	NA	NA	1105	rs4364717-A	rs4364717	0	4364717	regulatory_region_variant	TRUE	0.55	1e-10	10	NA	0.175	[0.12-0.23] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.55	NA	0.175
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q22.3	2	144888505	TEX41	TEX41	NA	NA	ENSG00000226674	NA	NA	rs1438896-T	rs1438896	0	1438896	intron_variant	FALSE	0.3	2e-15	14.698970004336019	NA	0.234	[0.18-0.29] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.3	NA	0.234
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	3q25.2	3	154990178	RP11- 439C8.2	NA - MME	NA	ENSG00000196549	NA	NA	33946	rs143112823-A	rs143112823	0	143112823	intergenic_variant	TRUE	0.09	1e-14	14	NA	0.403	[0.3-0.5] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.09	NA	0.403
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	11q13.3	11	69312240	MYEOV	MYEOV	NA	NA	ENSG00000172927	NA	NA	rs67330701-T	rs67330701	0	67330701	intron_variant	FALSE	0.09	2e-12	11.698970004336019	NA	0.367	[0.27-0.47] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.09	NA	0.367
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6q27	6	165764963	PDE10A	PDE10A	NA	NA	ENSG00000112541	NA	NA	rs147212971-T	rs147212971	0	147212971	intron_variant	FALSE	0.06	2e-9	8.698970004336019	NA	0.36	[0.24-0.48] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.06	NA	0.36
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q31.2	2	178921341	CCDC141	CCDC141	NA	NA	ENSG00000163492	NA	NA	rs79146658-T	rs79146658	0	79146658	intron_variant	FALSE	0.91	2e-10	9.698970004336019	NA	0.311	[0.21-0.41] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.91	NA	0.311
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q32.2	2	190574865	TMEM194B	RN7SKP179 - NAB1	ENSG00000251935	ENSG00000138386	NA	21385	71881	rs7592578-T	rs7592578	0	7592578	regulatory_region_variant	TRUE	0.19	1e-11	11	NA	0.24	[0.16-0.32] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.19	NA	0.24
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	15q25.1	15	78777658	ADAMTS7	ADAMTS7	NA	NA	ENSG00000136378	NA	NA	rs62012628-T	rs62012628	0	62012628	intron_variant	FALSE	0.29	5e-12	11.301029995663981	NA	0.238	[0.18-0.3] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.29	NA	0.238
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	15q26.2	15	94768842	chr15mb95	LINC02852 - LINC01197	ENSG00000285866	ENSG00000248441	NA	179583	417792	rs12906962-T	rs12906962	0	12906962	intergenic_variant	TRUE	0.68	6e-14	13.221848749616356	NA	0.221	[0.16-0.28] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.68	NA	0.221
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	4q26	4	119588124	PDE5A	PDE5A	NA	NA	ENSG00000138735	NA	NA	rs66887589-T	rs66887589	0	66887589	intron_variant	FALSE	0.52	3e-15	14.522878745280337	NA	0.215	[0.16-0.27] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.52	NA	0.215
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	20p12.3	20	8645624	PLCB1	PLCB1	NA	NA	ENSG00000182621	NA	NA	rs6108168-A	rs6108168	0	6108168	intron_variant	FALSE	0.25	1e-11	11	NA	0.211	[0.15-0.27] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.25	NA	0.211
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	5q35.2	5	173950633	CPEB4	CPEB4	NA	NA	ENSG00000113742	NA	NA	rs72812846-A	rs72812846	0	72812846	intron_variant	FALSE	0.28	2e-11	10.698970004336019	NA	0.209	[0.15-0.27] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.28	NA	0.209
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	3p21.31	3	49876272	CAMKV, ACTBP13	ACTL11P	NA	NA	ENSG00000234667	NA	NA	rs36022378-T	rs36022378	0	36022378	non_coding_transcript_exon_variant	FALSE	0.8	5e-9	8.301029995663981	NA	0.202	[0.14-0.26] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.8	NA	0.202
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q35	2	217804009	TNS1	TNS1	NA	NA	ENSG00000079308	NA	NA	rs1063281-T	rs1063281	0	1063281	3_prime_UTR_variant	FALSE	0.6	1e-12	12	NA	0.2	[0.14-0.26] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.6	NA	0.2
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q11.2	2	96009418	GPAT2, FAHD2CP	RN7SL210P - FAHD2CP	ENSG00000275961	ENSG00000231584	NA	4568	1133	rs2579519-T	rs2579519	0	2579519	regulatory_region_variant	TRUE	0.63	5e-12	11.301029995663981	NA	0.197	[0.14-0.26] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.63	NA	0.197
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	15q22.31	15	66576734	RP11-321F6.1	LCTL - LINC01169	ENSG00000188501	ENSG00000259471	NA	10755	5456	rs7178615-A	rs7178615	0	7178615	intergenic_variant	TRUE	0.37	3e-10	9.522878745280337	NA	0.179	[0.12-0.24] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.37	NA	0.179
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1q42.13	1	227064925	CDC42BPA	CDC42BPA	NA	NA	ENSG00000143776	NA	NA	rs10916082-A	rs10916082	0	10916082	intron_variant	FALSE	0.73	8e-9	8.096910013008056	NA	0.177	[0.12-0.24] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.73	NA	0.177
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	3p14.3	3	56692618	FAM208A	TASOR - ARHGEF3	ENSG00000163946	ENSG00000163947	NA	9353	34800	rs9827472-T	rs9827472	0	9827472	intergenic_variant	TRUE	0.37	4e-10	9.397940008672037	NA	0.177	[0.12-0.24] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.37	NA	0.177
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1p32.1	1	59188070	FGGY	LINC01358, FGGY-DT	NA	NA	ENSG00000237352, ENSG00000224609	NA	NA	rs3889199-A	rs3889199	0	3889199	intron_variant	FALSE	0.71	2e-24	23.69897000433602	NA	0.351	[0.29-0.41] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.71	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	11q14.3	11	89491285	NOX4	NOX4	NA	NA	ENSG00000086991	NA	NA	rs2289125-A	rs2289125	0	2289125	5_prime_UTR_variant	FALSE	0.21	9e-22	21.045757490560675	NA	0.377	[0.3-0.46] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.21	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q35	2	215435759	FN1	FN1	NA	NA	ENSG00000115414	NA	NA	rs1250259-A	rs1250259	0	1250259	missense_variant	FALSE	0.74	9e-19	18.045757490560675	NA	0.314	[0.24-0.39] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.74	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	16q23.3	16	83012185	CDH13	CDH13	NA	NA	ENSG00000140945	NA	NA	rs7500448-A	rs7500448	0	7500448	intron_variant	FALSE	0.75	1e-19	19	NA	0.329	[0.25-0.41] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.75	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	18q12.3	18	45517785	SLC14A2	SLC14A2	NA	NA	ENSG00000132874	NA	NA	rs7236548-A	rs7236548	0	7236548	intron_variant	FALSE	0.18	2e-18	17.69897000433602	NA	0.352	[0.27-0.43] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.18	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6q25.1	6	152076778	ESR1	ESR1	NA	NA	ENSG00000091831	NA	NA	rs36083386-?	rs36083386	0	36083386	intron_variant	FALSE	0.11	2e-18	17.69897000433602	NA	0.439	[0.34-0.54] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.11	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6q22.31	6	121460244	GJA1	RNU4-35P - RNU4-76P	ENSG00000199458	ENSG00000201379	NA	6123	82242	rs11154027-T	rs11154027	0	11154027	intergenic_variant	TRUE	0.47	1e-10	10	NA	0.207	[0.15-0.27] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.47	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	12q14.3	12	65980467	chr12mb66	HMGA2 - MIR6074	ENSG00000149948	ENSG00000276878	NA	14176	43153	rs7312464-G	rs7312464	0	7312464	intergenic_variant	TRUE	0.51912487	5e-10	9.301029995663981	NA	0.2104	[0.14-0.28] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.51912487	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17p13.1	17	7668434	TP53, SLC2A4	TP53	NA	NA	ENSG00000141510	NA	NA	rs78378222-T	rs78378222	0	78378222	3_prime_UTR_variant	FALSE	0.99	2e-10	9.698970004336019	NA	0.904	[0.63-1.18] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.99	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	11p11.2	11	45186591	PRDM11	PRDM11	NA	NA	ENSG00000019485	NA	NA	rs11442819-?	rs11442819	0	11442819	intron_variant	FALSE	0.11	7e-9	8.154901959985743	NA	0.279	[0.18-0.38] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.11	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	10p11.22	10	31793730	ARHGAP12, ZEB1	Y_RNA - ARHGAP12	ENSG00000199964	ENSG00000165322	NA	37594	11668	rs10826995-T	rs10826995	0	10826995	intergenic_variant	TRUE	0.71	1e-9	9	NA	0.212	[0.15-0.27] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.71	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	16q21	16	65231799	chr16mb65	LINC02126 - LINC00922	ENSG00000259847	ENSG00000261742	NA	55086	52697	rs56249585-T	rs56249585	0	56249585	intron_variant	TRUE	0.53032183	9e-9	8.045757490560675	NA	0.1827	[0.12-0.25] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.53032183	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17q21.2	17	42165223	KCNH4, HSD17B1	KCNH4	NA	NA	ENSG00000089558	NA	NA	rs79089478-T	rs79089478	0	79089478	intron_variant	FALSE	0.97	3e-9	8.522878745280337	NA	0.584	[0.39-0.78] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.97	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	3q21.3	3	128483046	GATA2	GATA2	NA	NA	ENSG00000179348	NA	NA	rs62270945-T	rs62270945	0	62270945	intron_variant	FALSE	0.03	2e-9	8.698970004336019	NA	0.607	[0.41-0.8] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.03	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	4q34.1	4	173663512	chr4mb174	HAND2-AS1 - LINC02269	ENSG00000237125	ENSG00000250708	NA	3816	35570	rs17059668-C	rs17059668	0	17059668	intergenic_variant	TRUE	0.92	3e-8	7.522878745280337	NA	0.332	[0.21-0.45] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.92	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	19p13.2	19	10223767	chr19mb10	DNMT1, S1PR2	NA	NA	ENSG00000130816, ENSG00000267534	NA	NA	rs2116941-C	rs2116941	0	2116941	3_prime_UTR_variant	FALSE	0.80902067	3e-8	7.522878745280337	NA	0.2198	[0.14-0.3] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.80902067	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	14q32.12	14	93989208	chr14mb94	CCDC197, CCDC197	NA	NA	ENSG00000280668, ENSG00000175699	NA	NA	rs12434998-C	rs12434998	0	12434998	intron_variant	FALSE	0.365899476	2e-8	7.698970004336019	NA	0.1894	[0.12-0.26] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.365899476	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	8p11.21	8	42467247	SLC20A2	SLC20A2	NA	NA	ENSG00000168575	NA	NA	rs2978456-T	rs2978456	0	2978456	intron_variant	FALSE	0.55	1e-8	8	NA	0.188	[0.13-0.25] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.55	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17q21.31	17	43983263	PYY	PYY	NA	NA	ENSG00000131096	NA	NA	rs62080325-A	rs62080325	0	62080325	intron_variant	FALSE	0.66	4e-8	7.3979400086720375	NA	0.186	[0.13-0.24] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.66	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	9p22.1	9	19334017	chr9mb19	DENND4C	NA	NA	ENSG00000137145	NA	NA	rs2803122-T	rs2803122	0	2803122	intron_variant	FALSE	0.434754262	9e-8	7.045757490560675	NA	0.1682	[0.11-0.23] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.434754262	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2p11.2	2	85264242	TCF7L1	TCF7L1	NA	NA	ENSG00000152284	NA	NA	rs11689667-T	rs11689667	0	11689667	intron_variant	FALSE	0.54	2e-8	7.698970004336019	NA	0.176	[0.12-0.23] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.54	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17q21.2	17	42384786	KCNH4, HSD17B1	STAT3	NA	NA	ENSG00000168610	NA	NA	rs62075782-C	rs62075782	0	62075782	intron_variant	FALSE	0.239640408	6e-8	7.221848749616356	NA	0.2337	[0.15-0.32] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.239640408	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	4q31.23	4	147506351	chr4mb148	EDNRA, GTF2F2P1	NA	NA	ENSG00000151617, ENSG00000251254	NA	NA	rs78049276-C	rs78049276	0	78049276	non_coding_transcript_exon_variant	FALSE	0.133646953	1e-8	8	NA	0.2668	[0.18-0.36] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.133646953	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	16q22.1	16	70199932	NFAT5	CLEC18C - SMG1P7	ENSG00000157335	ENSG00000261556	NA	12571	19642	rs147381998-A	rs147381998	0	147381998	intergenic_variant	TRUE	0.026754249	6e-8	7.221848749616356	NA	0.9886	[0.63-1.35] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.026754249	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	16q22.1	16	69869262	NFAT5	WWP2	NA	NA	ENSG00000198373	NA	NA	rs141767645-T	rs141767645	0	141767645	intron_variant	FALSE	0.015045874	2e-8	7.698970004336019	NA	1.3023	[0.85-1.76] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.015045874	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	12p13.32	12	4275678	chr12mb4	CCND2-AS1, CCND2	NA	NA	ENSG00000255920, ENSG00000118971	NA	NA	rs76895963-G	rs76895963	0	76895963	intron_variant	FALSE	0.021275654	2e-7	6.698970004336019	NA	0.725	[0.45-1] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.021275654	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17p13.1	17	7624628	TP53, SLC2A4	SHBG	NA	NA	ENSG00000129214	NA	NA	rs62059837-C	rs62059837	0	62059837	intron_variant	FALSE	0.114845119	2e-7	6.698970004336019	NA	0.2634	[0.16-0.36] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.114845119	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6q14.3	6	84509360	chr6mb85	LINC01611	NA	NA	ENSG00000231776	NA	NA	rs36114380-G	rs36114380	0	36114380	intron_variant	FALSE	0.134367627	3e-7	6.522878745280337	NA	0.2407	[0.15-0.33] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.134367627	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	7q33	7	136918569	chr7mb136	CHRM2	NA	NA	ENSG00000181072	NA	NA	rs71784944-?	rs71784944	0	71784944	intron_variant	FALSE	0.212859059	3e-7	6.522878745280337	NA	0.2016	[0.12-0.28] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.212859059	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17q21.32	17	48196567	HOXB7	SKAP1-AS1, SKAP1	NA	NA	ENSG00000263787, ENSG00000141293	NA	NA	rs9903692-A	rs9903692	0	9903692	intron_variant	FALSE	0.20348838	1e-7	7	NA	0.1989	[0.12-0.27] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.20348838	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	15q22.2	15	62516340	chr15mb62	TLN2	NA	NA	ENSG00000171914	NA	NA	rs956006-T	rs956006	0	956006	intron_variant	FALSE	0.326301444	1e-7	7	NA	0.1789	[0.11-0.25] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.326301444	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6q27	6	169187008	THBS2	LINC02544 - THBS2	ENSG00000261039	ENSG00000186340	NA	4167	28772	rs1322639-A	rs1322639	0	1322639	intergenic_variant	TRUE	0.78	5e-17	16.30102999566398	NA	0.316	[0.24-0.39] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.78	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	8q24.3	8	140049929	TRAPPC9	TRAPPC9	NA	NA	ENSG00000167632	NA	NA	rs4454254-A	rs4454254	0	4454254	intron_variant	FALSE	0.63	5e-16	15.301029995663981	NA	0.261	[0.2-0.32] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.63	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1p34.3	1	37990219	SF3A3	SF3A3 - RNU6-510P	ENSG00000183431	ENSG00000212541	NA	144	1243	rs4360494-C	rs4360494	0	4360494	regulatory_region_variant	TRUE	0.55	4e-16	15.397940008672037	NA	0.278	[0.22-0.34] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.55	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	10p11.23	10	30028144	KIAA1462	JCAD	NA	NA	ENSG00000165757	NA	NA	rs9337951-A	rs9337951	0	9337951	synonymous_variant	FALSE	0.34	3e-15	14.522878745280337	NA	0.28	[0.2-0.36] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.34	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6q25.3	6	159278093	FNDC1	FNDC1 - NA	ENSG00000164694	NA	NA	5985	NA	rs449789-C	rs449789	0	449789	intergenic_variant	TRUE	0.14	2e-15	14.698970004336019	NA	0.359	[0.26-0.46] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.14	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	9q33.3	9	125138717	SCAI	SCAI	NA	NA	ENSG00000173611	NA	NA	rs72765298-T	rs72765298	0	72765298	intron_variant	FALSE	0.87	3e-14	13.522878745280337	NA	0.374	[0.28-0.47] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.87	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17p13.1	17	6570508	KIAA0753	PITPNM3 - KIAA0753	ENSG00000091622	ENSG00000198920	NA	13953	7639	rs7226020-T	rs7226020	0	7226020	regulatory_region_variant	TRUE	0.56	2e-14	13.698970004336019	NA	0.256	[0.2-0.31] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.56	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	4q32.3	4	168795997	PALLD	PALLD	NA	NA	ENSG00000129116	NA	NA	rs1566497-A	rs1566497	0	1566497	intron_variant	FALSE	0.42	2e-13	12.698970004336019	NA	0.236	[0.18-0.29] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.42	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	11q23.3	11	117412960	CEP164	CEP164	NA	NA	ENSG00000110274	NA	NA	rs8258-T	rs8258	0	8258	3_prime_UTR_variant	FALSE	0.38	3e-13	12.522878745280337	NA	0.236	[0.18-0.29] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.38	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	20p11.23	20	19485263	SLC24A3	SLC24A3	NA	NA	ENSG00000185052	NA	NA	rs6081613-A	rs6081613	0	6081613	intron_variant	FALSE	0.28	2e-13	12.698970004336019	NA	0.263	[0.18-0.34] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.28	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	16q22.1	16	70084312	NFAT5	PDXDC2P-NPIPB14P - PDPR	ENSG00000196696	ENSG00000090857	NA	18364	30020	rs200337503-?	rs200337503	0	200337503	intergenic_variant	TRUE	0.026169631	7e-13	12.154901959985743	NA	1.3056	[0.95-1.66] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.026169631	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	7p14.1	7	40408372	SUGCT	SUGCT	NA	NA	ENSG00000175600	NA	NA	rs76206723-A	rs76206723	0	76206723	intron_variant	FALSE	0.1	7e-12	11.154901959985743	NA	0.346	[0.25-0.44] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.1	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17q23.2	17	62689790	MRC2	MRC2	NA	NA	ENSG00000011028	NA	NA	rs740698-T	rs740698	0	740698	intron_variant	FALSE	0.56	3e-12	11.522878745280337	NA	0.228	[0.17-0.29] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.56	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2p24.1	2	20682080	C2orf43	GDF7 - LDAH	ENSG00000143869	ENSG00000118961	NA	2837	1934	rs2289081-C	rs2289081	0	2289081	regulatory_region_variant	TRUE	0.36	6e-12	11.221848749616356	NA	0.223	[0.16-0.28] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.36	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1p32.2	1	56111252	RP4-710M16.1, PPAP2B	NA - RPSAP20	NA	ENSG00000229871	NA	NA	96315	rs112557609-A	rs112557609	0	112557609	intergenic_variant	TRUE	0.35	7e-12	11.154901959985743	NA	0.227	[0.17-0.29] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.35	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2p14	2	65056838	CEP68	CEP68	NA	NA	ENSG00000011523	NA	NA	rs74181299-T	rs74181299	0	74181299	intron_variant	FALSE	0.62	1e-12	12	NA	0.23	[0.17-0.29] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.62	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	22q11.21	22	19980457	ARVCF	ARVCF	NA	NA	ENSG00000099889	NA	NA	rs12628032-T	rs12628032	0	12628032	non_coding_transcript_exon_variant	FALSE	0.3	6e-12	11.221848749616356	NA	0.24	[0.18-0.3] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.3	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2p21	2	46136197	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs11690961-A	rs11690961	0	11690961	intron_variant	FALSE	0.88	4e-12	11.397940008672037	NA	0.34	[0.24-0.44] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.88	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	16q22.1	16	70721707	VAC14	VAC14	NA	NA	ENSG00000103043	NA	NA	rs117006983-A	rs117006983	0	117006983	intron_variant	FALSE	0.01	4e-12	11.397940008672037	NA	0.986	[0.71-1.26] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.01	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	14q32.2	14	98121293	RP11-61O1.1	NA - LINC02295	NA	ENSG00000258511	NA	NA	14781	rs9323988-T	rs9323988	0	9323988	intron_variant	TRUE	0.63	4e-11	10.397940008672037	NA	0.212	[0.15-0.27] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.63	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	5q14.1	5	78541966	LHFPL2	LHFPL2	NA	NA	ENSG00000145685	NA	NA	rs10057188-A	rs10057188	0	10057188	intron_variant	FALSE	0.46	7e-11	10.154901959985743	NA	0.205	[0.15-0.26] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.46	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	22q13.2	22	41642782	XRCC6	XRCC6	NA	NA	ENSG00000196419	NA	NA	rs73161324-T	rs73161324	0	73161324	intron_variant	FALSE	0.05	3e-11	10.522878745280337	NA	0.496	[0.36-0.63] unit increase	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.05	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	19q13.32	19	44908822	chr19mb45	APOE	NA	NA	ENSG00000130203	NA	NA	rs7412-T	rs7412	0	7412	missense_variant	FALSE	0.078406042	4e-10	9.397940008672037	NA	0.3826	[0.26-0.5] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.078406042	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	12q22	12	94486966	CCDC41	CEP83-DT - RN7SL483P	ENSG00000278916	ENSG00000244091	NA	24482	28510	rs139236208-A	rs139236208	0	139236208	intergenic_variant	TRUE	0.1	2e-10	9.698970004336019	NA	0.363	[0.25-0.48] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.1	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Pulse pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1p36.22	1	9381890	chr1mb9	SPSB1 - LINC02606	ENSG00000171621	ENSG00000284693	NA	12358	43204	rs9662255-A	rs9662255	0	9662255	intergenic_variant	TRUE	0.43	2e-10	9.698970004336019	NA	0.207	[0.15-0.27] unit decrease	Affymetrix [~ 9800000] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST004278	Genome-wide genotyping array	0.43	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q24.2	2	159898436	LY75, LY75-CD302	LY75-CD302, LY75	NA	NA	ENSG00000248672, ENSG00000054219	NA	NA	rs76840964-G	rs76840964	0	76840964	intron_variant	FALSE	0.1249	4e-10	9.397940008672037	NA	0.03454823	[0.024-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1249	NA	0.03454823
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q33.1	2	201304409	ALS2CR12	FLACC1	NA	NA	ENSG00000155749	NA	NA	rs6712091-C	rs6712091	0	6712091	intron_variant	FALSE	0.6432	1e-9	9	NA	0.02308301	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6432	NA	0.02308301
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q34	2	210678331	CPS1	CPS1	NA	NA	ENSG00000021826	NA	NA	rs715-C	rs715	0	715	3_prime_UTR_variant	FALSE	0.3126	1e-9	9	NA	0.02410037	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3126	NA	0.02410037
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q35	2	218273447	PNKD	PNKD	NA	NA	ENSG00000127838	NA	NA	rs10716631-G	rs10716631	0	10716631	intron_variant	FALSE	0.5411	6e-10	9.221848749616356	NA	0.02356192	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5411	NA	0.02356192
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q36.3	2	226432279	intergenic	NA	NA	NA	NA	NA	NA	rs11684299-T	rs11684299	0	11684299	intergenic_variant	TRUE	0.1941	5e-20	19.30102999566398	NA	0.04250255	[0.033-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1941	NA	0.04250255
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q37.1	2	233370615	DGKD, AC019221.4	DGKD, DGKD	NA	NA	ENSG00000280873, ENSG00000077044	NA	NA	rs60485593-C	rs60485593	0	60485593	intron_variant	FALSE	0.1196	5e-12	11.301029995663981	NA	0.03923927	[0.028-0.05] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1196	NA	0.03923927
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3p25.2	3	12225304	intergenic	SYN2 - GSTM5P1	ENSG00000157152	ENSG00000236062	NA	33272	32497	rs1822534-G	rs1822534	0	1822534	intergenic_variant	TRUE	0.3941	2e-33	32.69897000433602	NA	0.04510142	[0.038-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3941	NA	0.04510142
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3p24.3	3	18276637	TBC1D5	TBC1D5	NA	NA	ENSG00000131374	NA	NA	rs7427439-G	rs7427439	0	7427439	intron_variant	FALSE	0.7431	5e-13	12.301029995663981	NA	0.03032733	[0.022-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7431	NA	0.03032733
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3p14.3	3	56815721	ARHGEF3	ARHGEF3	NA	NA	ENSG00000163947	NA	NA	rs1354034-C	rs1354034	0	1354034	intron_variant	FALSE	0.6034	2e-21	20.69897000433602	NA	0.03542415	[0.028-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6034	NA	0.03542415
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q21.1	3	123114156	PDIA5	PDIA5	NA	NA	ENSG00000065485	NA	NA	rs3804749-T	rs3804749	0	3804749	intron_variant	FALSE	0.5927	7e-11	10.154901959985743	NA	0.02445101	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5927	NA	0.02445101
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q21.2	3	124716263	KALRN	KALRN	NA	NA	ENSG00000160145	NA	NA	rs332507-C	rs332507	0	332507	intron_variant	FALSE	0.2229	1e-11	11	NA	0.03009294	[0.021-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2229	NA	0.03009294
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q26.2	3	169127630	MECOM	MECOM	NA	NA	ENSG00000085276	NA	NA	rs2901381-G	rs2901381	0	2901381	intron_variant	FALSE	0.606	5e-24	23.30102999566398	NA	0.03793656	[0.031-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.606	NA	0.03793656
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q26.2	3	169192485	MECOM	MECOM	NA	NA	ENSG00000085276	NA	NA	rs9290361-A	rs9290361	0	9290361	intron_variant	FALSE	0.0903	1e-22	22	NA	0.06246271	[0.05-0.075] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0903	NA	0.06246271
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q26.31	3	172576710	RP11-408H1.3	LINC02068	NA	NA	ENSG00000223387	NA	NA	rs79287178-A	rs79287178	0	79287178	intron_variant	FALSE	0.0338	5e-10	9.301029995663981	NA	0.0670373	[0.046-0.088] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0338	NA	0.0670373
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q27.1	3	184365748	POLR2H, EIF2B5	POLR2H	NA	NA	ENSG00000163882	NA	NA	rs75389224-T	rs75389224	0	75389224	intron_variant	FALSE	0.1207	9e-42	41.045757490560675	NA	0.07660589	[0.066-0.088] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1207	NA	0.07660589
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q27.1	3	184372454	THPO	THPO	NA	NA	ENSG00000090534	NA	NA	rs78565404-T	rs78565404	0	78565404	3_prime_UTR_variant	FALSE	0.0538	4e-74	73.39794000867204	NA	0.1550234	[0.14-0.17] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0538	NA	0.1550234
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	NA	NA	NA	THPO	NA	NA	NA	NA	NA	NA	chr3:184090266-T	chr3:184090266	0	NA	NA	TRUE	0.5321	5e-71	70.30102999566398	NA	0.06530524	[0.058-0.072] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5321	NA	0.06530524
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	NA	NA	NA	THPO, EIF2B5	NA	NA	NA	NA	NA	NA	chr3:184091102-G	chr3:184091102	0	NA	NA	TRUE	0.0092	9e-63	62.045757490560675	NA	0.3363599	[0.3-0.38] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0092	NA	0.3363599
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q27.1	3	184375252	THPO, EIF2B5	THPO	NA	NA	ENSG00000090534	NA	NA	rs34623301-A	rs34623301	0	34623301	intron_variant	FALSE	0.2154	4e-65	64.39794000867204	NA	0.07590098	[0.067-0.085] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2154	NA	0.07590098
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q27.1	3	184381484	CHRD	CHRD, THPO	NA	NA	ENSG00000090539, ENSG00000090534	NA	NA	rs149400260-CT	rs149400260	0	149400260	splice_region_variant	FALSE	0.0097	1e-9	9	NA	0.1149013	[0.078-0.152] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0097	NA	0.1149013
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q27.2	3	185770515	IGF2BP2	IGF2BP2	NA	NA	ENSG00000073792	NA	NA	rs35430985-A	rs35430985	0	35430985	intron_variant	FALSE	0.27	1e-13	13	NA	0.03068133	[0.023-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.27	NA	0.03068133
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	3q29	3	196784238	PAK2	PAK2	NA	NA	ENSG00000180370	NA	NA	rs11294619-T	rs11294619	0	11294619	intron_variant	FALSE	0.4968	3e-18	17.522878745280337	NA	0.03266217	[0.025-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4968	NA	0.03266217
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	4p16.3	4	3442204	HGFAC	HGFAC	NA	NA	ENSG00000109758	NA	NA	rs13108218-G	rs13108218	0	13108218	intron_variant	FALSE	0.6159	3e-9	8.522878745280337	NA	0.0226498	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6159	NA	0.0226498
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	4p16.1	4	7043344	TADA2B, RP11-367J11.2	TADA2B	NA	NA	ENSG00000173011	NA	NA	rs568868093-TGCGGCG	rs568868093	0	568868093	intron_variant	FALSE	0.6064	4e-14	13.397940008672037	NA	0.02841025	[0.021-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6064	NA	0.02841025
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	4q12	4	54542832	intergenic	LINC02283 - LINC02260	ENSG00000248184	ENSG00000250456	NA	186878	60379	rs218265-C	rs218265	0	218265	intergenic_variant	TRUE	0.1571	3e-10	9.522878745280337	NA	0.03203843	[0.022-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1571	NA	0.03203843
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p21.31	3	47885994	MAP4	MAP4	NA	NA	ENSG00000047849	NA	NA	rs319690-T	rs319690	0	319690	intron_variant	FALSE	NA	1e-16	16	NA	0.208	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	19q12	19	29830654	CCNE1, URI1	CCNE1 - PPIAP58	ENSG00000105173	ENSG00000267258	NA	6342	90528	rs34331990-T	rs34331990	0	34331990	regulatory_region_variant	TRUE	NA	3e-10	9.522878745280337	NA	0.154	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q11.23	7	73562919	BCL7B, TBL2	BCL7B - TBL2	ENSG00000106635	ENSG00000106638	NA	5229	4618	rs34594435-C	rs34594435	0	34594435	intergenic_variant	TRUE	NA	1e-9	9	NA	0.183	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p25.3	3	11248436	HRH1	HRH1	NA	NA	ENSG00000196639	NA	NA	rs347591-G	rs347591	0	347591	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	0.108	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q22.1	6	117495189	DCBLD1	DCBLD1	NA	NA	ENSG00000164465	NA	NA	rs35189230-G	rs35189230	0	35189230	intron_variant	FALSE	NA	1e-8	8	NA	0.239	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17p11.2	17	16271711	PIGL	PIGL	NA	NA	ENSG00000108474	NA	NA	rs35565381-T	rs35565381	0	35565381	intron_variant	FALSE	NA	3e-9	8.522878745280337	NA	0.14	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q15.3	15	43726458	CKMT1A, CATSPER2P1	STRCP1 - CATSPER2P1	ENSG00000166763	ENSG00000205771	NA	8198	460	rs35654783-T	rs35654783	0	35654783	intergenic_variant	TRUE	NA	1e-10	10	NA	0.166	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.4	11	9732054	SWAP70	SWAP70	NA	NA	ENSG00000133789	NA	NA	rs360158-G	rs360158	0	360158	intron_variant	FALSE	NA	5e-12	11.301029995663981	NA	0.165	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q22.1	6	115990600	FRK	FRK	NA	NA	ENSG00000111816	NA	NA	rs36061333-C	rs36061333	0	36061333	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.16	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	14q12	14	24366294	RIPK3, NFATC4	NFATC4, NFATC4	NA	NA	ENSG00000100968, ENSG00000285485	NA	NA	rs36226649-T	rs36226649	0	36226649	intron_variant	FALSE	NA	3e-9	8.522878745280337	NA	0.297	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20p11.21	20	23521492	CSTT	CST13P	NA	NA	ENSG00000204663	NA	NA	rs369386096-C	rs369386096	0	369386096	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	9.788	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p11.2	2	86141681	PTCD3	PTCD3	NA	NA	ENSG00000132300	NA	NA	rs3731818-G	rs3731818	0	3731818	3_prime_UTR_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.117	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q13.1	11	65641466	SIPA1	SIPA1	NA	NA	ENSG00000213445	NA	NA	rs3741378-C	rs3741378	0	3741378	missense_variant	FALSE	NA	8e-6	5.096910013008056	NA	0.152	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p21.31	3	49732599	IP6K1	IP6K1	NA	NA	ENSG00000176095	NA	NA	rs3749237-G	rs3749237	0	3749237	intron_variant	FALSE	NA	4e-11	10.397940008672037	NA	0.165	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.2	11	16880721	PLEKHA7	PLEKHA7	NA	NA	ENSG00000166689	NA	NA	rs381815-C	rs381815	0	381815	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.122	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p21.1	3	53523985	NR	CACNA1D	NA	NA	ENSG00000157388	NA	NA	rs3821843-G	rs3821843	0	3821843	intron_variant	FALSE	NA	6e-8	7.221848749616356	NA	0.139	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q36.1	7	150993088	NOS3	NOS3	NA	NA	ENSG00000164867	NA	NA	rs3918226-C	rs3918226	0	3918226	intron_variant	FALSE	NA	4e-23	22.397940008672037	NA	0.474	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q14.3	2	123263214	TSN, CNTNAP5	NA	NA	NA	NA	NA	NA	rs3923097-T	rs3923097	0	3923097	intergenic_variant	TRUE	NA	1e-8	8	NA	0.273	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	13q34	13	113801017	FAM70B	TMEM255B	NA	NA	ENSG00000184497	NA	NA	rs3934939-A	rs3934939	0	3934939	intron_variant	FALSE	NA	8e-9	8.096910013008056	NA	0.163	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q23.33	10	94890571	CYP2C19, CYP2C9	RPL7AP52 - CYP2C9	ENSG00000225354	ENSG00000138109	NA	7228	48087	rs4110517-A	rs4110517	0	4110517	intergenic_variant	TRUE	NA	2e-6	5.698970004336019	NA	0.135	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q21.2	3	124833120	ITGB5	ITGB5	NA	NA	ENSG00000082781	NA	NA	rs4141663-C	rs4141663	0	4141663	intron_variant	FALSE	NA	7e-8	7.154901959985743	NA	0.126	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q26.2	3	169383098	MECOM	MECOM	NA	NA	ENSG00000085276	NA	NA	rs419076-T	rs419076	0	419076	intron_variant	FALSE	NA	6e-19	18.221848749616356	NA	0.207	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q31.21	4	144350802	GYPA, HHIP-AS1	NA	NA	NA	NA	NA	NA	rs4292285-T	rs4292285	0	4292285	intron_variant	TRUE	NA	7e-11	10.154901959985743	NA	0.154	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17q23.3	17	63478937	ACE	ACE	NA	NA	ENSG00000159640	NA	NA	rs4295-C	rs4295	0	4295	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.14	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q22.3	5	115039855	KCNN2, TRIM36	NA - TRIM36	NA	ENSG00000152503	NA	NA	84907	rs4475250-G	rs4475250	0	4475250	intergenic_variant	TRUE	NA	7e-9	8.154901959985743	NA	0.136	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q24.31	10	100796696	PAX2	PAX2	NA	NA	ENSG00000075891	NA	NA	rs4551692-G	rs4551692	0	4551692	intron_variant	FALSE	NA	1e-11	11	NA	0.255	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16q24.3	16	89615598	DPEP1	DPEP1	NA	NA	ENSG00000015413	NA	NA	rs460105-T	rs460105	0	460105	intron_variant	FALSE	NA	4e-12	11.397940008672037	NA	0.178	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1q42.13	1	227924420	WNT9A	WNT9A	NA	NA	ENSG00000143816	NA	NA	rs4653889-A	rs4653889	0	4653889	intron_variant	FALSE	NA	1e-10	10	NA	0.152	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q27.2	3	185589575	SENP2	SENP2	NA	NA	ENSG00000163904	NA	NA	rs4686683-T	rs4686683	0	4686683	intron_variant	FALSE	NA	4e-13	12.397940008672037	NA	0.172	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q26	6	163711969	QKI, C6orf118	NA	NA	NA	NA	NA	NA	rs4709746-C	rs4709746	0	4709746	intron_variant	TRUE	NA	4e-8	7.3979400086720375	NA	0.19	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6p22.3	6	22136033	LINC00340/LOC729177	NBAT1, CASC15	NA	NA	ENSG00000260455, ENSG00000272168	NA	NA	rs4712656-G	rs4712656	0	4712656	non_coding_transcript_exon_variant	FALSE	NA	1e-7	7	NA	0.124	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.2	11	16281393	SOX6	SOX6	NA	NA	ENSG00000110693	NA	NA	rs4757391-C	rs4757391	0	4757391	intron_variant	FALSE	NA	7e-16	15.154901959985743	NA	0.231	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17q25.1	17	75954135	ACOX1	ACOX1	NA	NA	ENSG00000161533	NA	NA	rs4788913-G	rs4788913	0	4788913	intron_variant	FALSE	NA	8e-7	6.096910013008056	NA	0.122	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	19p13.11	19	17108160	MYO9B	MYO9B	NA	NA	ENSG00000099331	NA	NA	rs4808569-C	rs4808569	0	4808569	intron_variant	FALSE	NA	5e-8	7.301029995663981	NA	0.162	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q22.1	11	100772406	NR	ARHGAP42	NA	NA	ENSG00000165895	NA	NA	rs486023-G	rs486023	0	486023	intron_variant	FALSE	NA	3e-23	22.522878745280337	NA	0.254	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q15.1	15	41794142	MAPKBP1	MAPKBP1	NA	NA	ENSG00000137802	NA	NA	rs4923910-G	rs4923910	0	4923910	intron_variant	FALSE	NA	4e-13	12.397940008672037	NA	0.178	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q26.1	15	90861558	NR	RN7SL363P - FURIN	ENSG00000241869	ENSG00000140564	NA	5351	7030	rs4932371-T	rs4932371	0	4932371	intergenic_variant	TRUE	NA	1e-17	17	NA	0.225	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q31.1	2	176147842	HOXD-AS2, MIR10B	HOXD3	NA	NA	ENSG00000128652	NA	NA	rs4972805-C	rs4972805	0	4972805	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.143	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q26.2	15	96092670	LOC145820, MIR1469	NA - NR2F2-AS1	NA	ENSG00000247809	NA	NA	17370	rs4984497-T	rs4984497	0	4984497	intron_variant	TRUE	NA	5e-9	8.301029995663981	NA	0.148	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	9q34.2	9	133273983	ABO	ABO, ABO	NA	NA	ENSG00000175164, ENSG00000281879	NA	NA	rs507666-G	rs507666	0	507666	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.169	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p36.22	1	11836799	NR	CLCN6	NA	NA	ENSG00000011021	NA	NA	rs55892892-C	rs55892892	0	55892892	intron_variant	FALSE	NA	4e-18	17.397940008672037	NA	0.451	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1q25.1	1	175142625	TNN	TNN	NA	NA	ENSG00000120332	NA	NA	rs567058829-C	rs567058829	0	567058829	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.197	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q22.3	2	144924003	DKFZp686O1327	TEX41	NA	NA	ENSG00000226674	NA	NA	rs58117425-G	rs58117425	0	58117425	intron_variant	FALSE	NA	8e-12	11.096910013008056	NA	0.192	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q13.32	20	59176062	SLMO2, ZNF831	ZNF831	NA	NA	ENSG00000124203	NA	NA	rs6015450-A	rs6015450	0	6015450	intron_variant	FALSE	NA	3e-27	26.522878745280337	NA	0.392	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q13.13	20	48693178	PREX1	PREX1	NA	NA	ENSG00000124126	NA	NA	rs6019378-C	rs6019378	0	6019378	intron_variant	FALSE	NA	2e-11	10.698970004336019	NA	0.156	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q11.21	20	31581870	HM13-AS1, ID1	RNU6-384P - ID1	ENSG00000201770	ENSG00000125968	NA	678	23413	rs6060114-T	rs6060114	0	6060114	TF_binding_site_variant	TRUE	NA	7e-13	12.154901959985743	NA	0.237	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20p12.2	20	10986566	NR	FAT1P1 - LINC02871	ENSG00000217809	ENSG00000125899	NA	97478	9727	rs6108787-T	rs6108787	0	6108787	intron_variant	TRUE	NA	2e-21	20.69897000433602	NA	0.223	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q12	20	41623190	CHD6, PTPRT	CHD6 - RNU6-1018P	ENSG00000124177	ENSG00000252386	NA	4806	61796	rs6129880-T	rs6129880	0	6129880	intergenic_variant	TRUE	NA	2e-9	8.698970004336019	NA	0.174	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p11.12	11	48902204	OR4A47, TRIM51GP	NA - TRIM51CP	NA	ENSG00000249910	NA	NA	43490	rs61448762-G	rs61448762	0	61448762	intergenic_variant	TRUE	NA	3e-6	5.522878745280337	NA	0.172	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p13	11	31799919	PAX6	PAX6	NA	NA	ENSG00000007372	NA	NA	rs61879810-A	rs61879810	0	61879810	intron_variant	FALSE	NA	1e-9	9	NA	0.198	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2017-06-26	28283553	Srinivasan L	2017-03-10	Arch Dis Child Fetal Neonatal Ed	www.ncbi.nlm.nih.gov/pubmed/28283553	Genome-wide association study of sepsis in extremely premature infants.	Sepsis in extremely premature infants	155 European ancestry cases, 190 non-European ancestry cases, 184 European ancestry controls, 222 non-European ancestry controls	NA	16q24.1	16	86870529	FOXC2, FOXL1	NA	NA	NA	NA	NA	NA	rs13380717-?	rs13380717	0	13380717	intergenic_variant	TRUE	NR	1e-7	7	NA	NA	NA	Illumina [7200000] (imputed)	N	Neonatal sepsis	http://purl.obolibrary.org/obo/HP_0040187	GCST004230	Genome-wide genotyping array	NA	NA	NA
2017-06-26	28283553	Srinivasan L	2017-03-10	Arch Dis Child Fetal Neonatal Ed	www.ncbi.nlm.nih.gov/pubmed/28283553	Genome-wide association study of sepsis in extremely premature infants.	Sepsis in extremely premature infants	155 European ancestry cases, 190 non-European ancestry cases, 184 European ancestry controls, 222 non-European ancestry controls	NA	4q13.1	4	58722063	intergenic	NA	NA	NA	NA	NA	NA	rs2412930-?	rs2412930	0	2412930	intergenic_variant	TRUE	NR	1e-6	6	NA	NA	NA	Illumina [7200000] (imputed)	N	Neonatal sepsis	http://purl.obolibrary.org/obo/HP_0040187	GCST004230	Genome-wide genotyping array	NA	NA	NA
2017-06-26	28283553	Srinivasan L	2017-03-10	Arch Dis Child Fetal Neonatal Ed	www.ncbi.nlm.nih.gov/pubmed/28283553	Genome-wide association study of sepsis in extremely premature infants.	Sepsis in extremely premature infants	155 European ancestry cases, 190 non-European ancestry cases, 184 European ancestry controls, 222 non-European ancestry controls	NA	6q26	6	163778989	intergenic	NA - RN7SL366P	NA	ENSG00000266128	NA	NA	61572	rs9456883-?	rs9456883	0	9456883	intron_variant	TRUE	NR	2e-6	5.698970004336019	NA	NA	NA	Illumina [7200000] (imputed)	N	Neonatal sepsis	http://purl.obolibrary.org/obo/HP_0040187	GCST004230	Genome-wide genotyping array	NA	NA	NA
2017-06-26	28283553	Srinivasan L	2017-03-10	Arch Dis Child Fetal Neonatal Ed	www.ncbi.nlm.nih.gov/pubmed/28283553	Genome-wide association study of sepsis in extremely premature infants.	Sepsis in extremely premature infants	155 European ancestry cases, 190 non-European ancestry cases, 184 European ancestry controls, 222 non-European ancestry controls	NA	2q35	2	218448631	intergenic	VIL1	NA	NA	ENSG00000127831	NA	NA	rs41461846-?	rs41461846	0	41461846	intron_variant	FALSE	NR	2e-6	5.698970004336019	NA	NA	NA	Illumina [7200000] (imputed)	N	Neonatal sepsis	http://purl.obolibrary.org/obo/HP_0040187	GCST004230	Genome-wide genotyping array	NA	NA	NA
2017-06-26	28283553	Srinivasan L	2017-03-10	Arch Dis Child Fetal Neonatal Ed	www.ncbi.nlm.nih.gov/pubmed/28283553	Genome-wide association study of sepsis in extremely premature infants.	Sepsis in extremely premature infants	155 European ancestry cases, 190 non-European ancestry cases, 184 European ancestry controls, 222 non-European ancestry controls	NA	NA	NA	NA	intergenic	NA	NA	NA	NA	NA	NA	chr2:219344165-?	chr2:219344165	0	NA	NA	TRUE	NR	2e-6	5.698970004336019	NA	NA	NA	Illumina [7200000] (imputed)	N	Neonatal sepsis	http://purl.obolibrary.org/obo/HP_0040187	GCST004230	Genome-wide genotyping array	NA	NA	NA
2017-06-26	28283553	Srinivasan L	2017-03-10	Arch Dis Child Fetal Neonatal Ed	www.ncbi.nlm.nih.gov/pubmed/28283553	Genome-wide association study of sepsis in extremely premature infants.	Sepsis in extremely premature infants	155 European ancestry cases, 190 non-European ancestry cases, 184 European ancestry controls, 222 non-European ancestry controls	NA	2q35	2	218510988	intergenic	USP37	NA	NA	ENSG00000135913	NA	NA	rs6717433-?	rs6717433	0	6717433	intron_variant	FALSE	NR	2e-6	5.698970004336019	NA	NA	NA	Illumina [7200000] (imputed)	N	Neonatal sepsis	http://purl.obolibrary.org/obo/HP_0040187	GCST004230	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	15q26.3	15	98704812	IGF1R	IGF1R	NA	NA	ENSG00000140443	NA	NA	rs4965426-A	rs4965426	0	4965426	intron_variant	FALSE	0.1428	1e-11	11	NA	0.03543915	[0.025-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1428	NA	0.03543915
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	16p12.1	16	28495107	APOBR	CLN3, APOBR	NA	NA	ENSG00000188603, ENSG00000184730	NA	NA	rs151233-T	rs151233	0	151233	synonymous_variant	FALSE	0.1309	2e-12	11.698970004336019	NA	0.03820972	[0.028-0.049] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1309	NA	0.03820972
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	16p11.2	16	29649973	intergenic	CA5AP1 - SPN	ENSG00000260133	ENSG00000197471	NA	13645	13006	rs9923283-T	rs9923283	0	9923283	regulatory_region_variant	TRUE	0.0634	7e-15	14.154901959985743	NA	0.05857671	[0.044-0.073] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0634	NA	0.05857671
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	16q22.1	16	68517374	intergenic	RPL35AP33 - ZFP90	ENSG00000241334	ENSG00000184939	NA	39804	12716	rs8050260-A	rs8050260	0	8050260	regulatory_region_variant	TRUE	0.2093	2e-9	8.698970004336019	NA	0.02726745	[0.018-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2093	NA	0.02726745
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	NA	NA	NA	RP11-345M22.1	NA	NA	NA	NA	NA	NA	chr16:79746461-C	chr16:79746461	0	NA	NA	TRUE	0.2938	6e-9	8.221848749616356	NA	0.02347806	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2938	NA	0.02347806
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	16q24.1	16	85382232	intergenic	GSE1	NA	NA	ENSG00000131149	NA	NA	rs4783187-C	rs4783187	0	4783187	intron_variant	FALSE	0.8779	2e-10	9.698970004336019	NA	0.03564258	[0.025-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.8779	NA	0.03564258
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	16q24.2	16	88491904	ZFPM1	ZFPM1	NA	NA	ENSG00000179588	NA	NA	rs59865663-A	rs59865663	0	59865663	intron_variant	FALSE	0.2043	1e-19	19	NA	0.0418761	[0.033-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2043	NA	0.0418761
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	16q24.3	16	88714277	CTU2	CTU2	NA	NA	ENSG00000174177	NA	NA	rs7191439-T	rs7191439	0	7191439	intron_variant	FALSE	0.8805	3e-10	9.522878745280337	NA	0.03665218	[0.025-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.8805	NA	0.03665218
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17p13.3	17	2055242	HIC1	HIC1	NA	NA	ENSG00000177374	NA	NA	rs4455005-A	rs4455005	0	4455005	splice_region_variant	FALSE	0.6408	4e-24	23.397940008672037	NA	0.03903548	[0.031-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6408	NA	0.03903548
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17p13.3	17	2254480	SMG6	SMG6	NA	NA	ENSG00000070366	NA	NA	rs12943566-G	rs12943566	0	12943566	intron_variant	FALSE	0.6526	5e-33	32.30102999566398	NA	0.04590243	[0.038-0.053] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6526	NA	0.04590243
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17p13.2	17	4937573	SLC25A11	SLC25A11	NA	NA	ENSG00000108528	NA	NA	rs1060431-A	rs1060431	0	1060431	3_prime_UTR_variant	FALSE	0.0736	1e-12	12	NA	0.04995122	[0.036-0.064] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0736	NA	0.04995122
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	NA	NA	NA	DNAH2	NA	NA	NA	NA	NA	NA	chr17:7721542-A	chr17:7721542	0	NA	NA	TRUE	0.1205	6e-9	8.221848749616356	NA	0.03441756	[0.023-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1205	NA	0.03441756
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	NA	NA	NA	TNFRSF13B	NA	NA	NA	NA	NA	NA	chr17:16843729-T	chr17:16843729	0	NA	NA	TRUE	0.0071	6e-11	10.221848749616356	NA	0.1592953	[0.11-0.21] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0071	NA	0.1592953
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17p11.2	17	16948873	TNFRSF13B	TNFRSF13B	NA	NA	ENSG00000240505	NA	NA	rs34557412-G	rs34557412	0	34557412	missense_variant	FALSE	0.0075	1e-19	19	NA	0.2026117	[0.16-0.25] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0075	NA	0.2026117
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17q12	17	35558885	SLFN14	SLFN14	NA	NA	ENSG00000236320	NA	NA	rs7503168-G	rs7503168	0	7503168	intron_variant	FALSE	0.1734	3e-17	16.522878745280337	NA	0.04060222	[0.031-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1734	NA	0.04060222
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17q12	17	37488149	DUSP14	TADA2A - DUSP14	ENSG00000277104	ENSG00000276023	NA	8424	1742	rs853195-A	rs853195	0	853195	intergenic_variant	TRUE	0.6378	1e-11	11	NA	0.02566215	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6378	NA	0.02566215
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17q21.31	17	44517387	intergenic	GPATCH8 - FZD2	ENSG00000186566	ENSG00000180340	NA	13957	40097	rs150568286-A	rs150568286	0	150568286	intergenic_variant	TRUE	0.0126	6e-12	11.221848749616356	NA	0.1147846	[0.082-0.147] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0126	NA	0.1147846
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17q22	17	57385980	MSI2	MSI2	NA	NA	ENSG00000153944	NA	NA	rs188761458-T	rs188761458	0	188761458	intron_variant	FALSE	0.0488	6e-26	25.221848749616356	NA	0.09090811	[0.074-0.108] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0488	NA	0.09090811
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17q22	17	58332680	BZRAP1-AS1	TSPOAP1-AS1	NA	NA	ENSG00000265148	NA	NA	rs2526377-G	rs2526377	0	2526377	intron_variant	FALSE	0.4428	1e-10	10	NA	0.02374733	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4428	NA	0.02374733
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	NA	NA	NA	APOH	NA	NA	NA	NA	NA	NA	chr17:64210580-C	chr17:64210580-C	0	NA	NA	TRUE	0.0301	7e-27	26.154901959985743	NA	0.1148124	[0.094-0.136] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0301	NA	0.1148124
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17q25.1	17	74694690	CD300LF	CD300LF, RAB37	NA	NA	ENSG00000186074, ENSG00000172794	NA	NA	rs9906320-A	rs9906320	0	9906320	3_prime_UTR_variant	FALSE	0.7757	3e-9	8.522878745280337	NA	0.02613192	[0.017-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7757	NA	0.02613192
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	NA	NA	NA	TMC6	NA	NA	NA	NA	NA	NA	chr17:76124810-AG	chr17:76124810	0	NA	NA	TRUE	0.223	2e-12	11.698970004336019	NA	0.03103511	[0.022-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.223	NA	0.03103511
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	17q25.3	17	80128718	intergenic	GAA - EIF4A3	ENSG00000171298	ENSG00000141543	NA	8837	5651	rs12451471-T	rs12451471	0	12451471	intergenic_variant	TRUE	0.3743	4e-9	8.397940008672037	NA	0.02233797	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3743	NA	0.02233797
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	18q11.2	18	23141009	CABLES1	CABLES1	NA	NA	ENSG00000134508	NA	NA	rs11082304-T	rs11082304	0	11082304	intron_variant	FALSE	0.5125	9e-22	21.045757490560675	NA	0.0351008	[0.028-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5125	NA	0.0351008
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	18q12.3	18	44434514	CTC-782O7.1	LINC01478	NA	NA	ENSG00000267337	NA	NA	rs11082383-C	rs11082383	0	11082383	intron_variant	FALSE	0.1321	1e-40	40	NA	0.0729372	[0.062-0.084] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1321	NA	0.0729372
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	12q24.31	12	120977112	HNF1A-AS1	HNF1A-AS1	NA	NA	ENSG00000241388	NA	NA	rs2255531-A	rs2255531	0	2255531	intron_variant	FALSE	0.3495	4e-16	15.397940008672037	NA	0.03117565	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3495	NA	0.03117565
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	12q24.31	12	121779004	TMEM120B, RHOF	RHOF, TMEM120B	NA	NA	ENSG00000139725, ENSG00000188735	NA	NA	rs11553699-G	rs11553699	0	11553699	3_prime_UTR_variant	FALSE	0.1352	6e-81	80.22184874961636	NA	0.1084553	[0.097-0.12] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1352	NA	0.1084553
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	12q24.31	12	121781881	TMEM120B	TMEM120B, RHOF	NA	NA	ENSG00000188735, ENSG00000139725	NA	NA	rs9165-C	rs9165	0	9165	3_prime_UTR_variant	FALSE	0.686	2e-26	25.69897000433602	NA	0.04331828	[0.035-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.686	NA	0.04331828
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	12q24.31	12	123193818	MPHOSPH9	MPHOSPH9	NA	NA	ENSG00000051825	NA	NA	rs34339938-G	rs34339938	0	34339938	intron_variant	FALSE	0.784	1e-12	12	NA	0.0319494	[0.023-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.784	NA	0.0319494
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	13q14.11	13	40919782	TPTE2P5, SUGT1P3	SUGT1P3, TPTE2P5	NA	NA	ENSG00000239827, ENSG00000168852	NA	NA	rs34213683-AAAT	rs34213683	0	34213683	intron_variant	FALSE	0.6689	9e-10	9.045757490560675	NA	0.02405798	[0.016-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6689	NA	0.02405798
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	13q21.33	13	70662479	intergenic	RNU6-54P - MTCL1P1	ENSG00000202433	ENSG00000226554	NA	202909	261185	rs670180-A	rs670180	0	670180	intergenic_variant	TRUE	0.5723	3e-24	23.522878745280337	NA	0.03792309	[0.031-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5723	NA	0.03792309
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	13q21.33	13	71768473	DACH1	DACH1	NA	NA	ENSG00000276644	NA	NA	rs9572786-G	rs9572786	0	9572786	intron_variant	FALSE	0.3775	2e-11	10.698970004336019	NA	0.02523779	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3775	NA	0.02523779
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	13q32.1	13	95242683	ABCC4	ABCC4	NA	NA	ENSG00000125257	NA	NA	rs9516547-T	rs9516547	0	9516547	intron_variant	FALSE	0.9241	2e-28	27.69897000433602	NA	0.07672933	[0.063-0.09] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.9241	NA	0.07672933
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	13q32.1	13	95248987	ABCC4	ABCC4	NA	NA	ENSG00000125257	NA	NA	rs4773860-T	rs4773860	0	4773860	intron_variant	FALSE	0.5186	3e-30	29.522878745280337	NA	0.04226349	[0.035-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5186	NA	0.04226349
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	13q33.3	13	108308033	TNFSF13B	TNFSF13B	NA	NA	ENSG00000102524	NA	NA	rs200748895-T	rs200748895	0	200748895	3_prime_UTR_variant	FALSE	0.0214	2e-12	11.698970004336019	NA	0.0970577	[0.07-0.124] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0214	NA	0.0970577
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	13q34	13	109840279	intergenic	IRS2 - RN7SKP10	ENSG00000185950	ENSG00000201161	NA	53696	74817	rs11841319-T	rs11841319	0	11841319	regulatory_region_variant	TRUE	0.1027	2e-22	21.69897000433602	NA	0.0594791	[0.048-0.071] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1027	NA	0.0594791
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q22.2	14	54705711	SAMD4A	SAMD4A	NA	NA	ENSG00000020577	NA	NA	rs8012145-T	rs8012145	0	8012145	intron_variant	FALSE	0.7325	3e-9	8.522878745280337	NA	0.02463193	[0.017-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7325	NA	0.02463193
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q23.3	14	65333158	MIR4708	PTBP1P - MIR4708	ENSG00000259078	ENSG00000266740	NA	51992	1959	rs11158588-A	rs11158588	0	11158588	intergenic_variant	TRUE	0.7872	5e-12	11.301029995663981	NA	0.03122528	[0.022-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7872	NA	0.03122528
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q24.1	14	68014850	RAD51B	RAD51B	NA	NA	ENSG00000182185	NA	NA	rs369495964-C	rs369495964	1	111996389	intron_variant	FALSE	0.1671	7e-19	18.154901959985743	NA	0.04376755	[0.034-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1671	NA	0.04376755
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q31.1	14	81418171	STON2	STON2	NA	NA	ENSG00000140022	NA	NA	rs3844535-G	rs3844535	0	3844535	non_coding_transcript_exon_variant	FALSE	0.6999	2e-9	8.698970004336019	NA	0.02390486	[0.016-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6999	NA	0.02390486
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q32.12	14	92646579	RIN3	RIN3	NA	NA	ENSG00000100599	NA	NA	rs112560164-A	rs112560164	0	112560164	intron_variant	FALSE	0.1912	3e-14	13.522878745280337	NA	0.03535423	[0.026-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1912	NA	0.03535423
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q32.12	14	93050053	ITPK1	ITPK1, ITPK1	NA	NA	ENSG00000100605, ENSG00000274958	NA	NA	rs36084521-G	rs36084521	0	36084521	intron_variant	FALSE	0.1097	2e-12	11.698970004336019	NA	0.04147957	[0.03-0.053] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1097	NA	0.04147957
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q32.2	14	100706106	intergenic	LINC00523 - DLK1	ENSG00000196273	ENSG00000185559	NA	30037	19599	rs9324022-C	rs9324022	0	9324022	intergenic_variant	TRUE	0.2105	3e-38	37.52287874528034	NA	0.05957088	[0.051-0.069] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2105	NA	0.05957088
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q32.2	14	100710432	intergenic	LINC00523 - DLK1	ENSG00000196273	ENSG00000185559	NA	34363	15273	rs1555405-A	rs1555405	0	1555405	regulatory_region_variant	TRUE	0.2489	4e-55	54.39794000867204	NA	0.06643256	[0.058-0.075] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2489	NA	0.06643256
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q32.31	14	102517937	intergenic	ANKRD9 - MIR4309	ENSG00000156381	ENSG00000266015	NA	8138	21707	rs3936840-C	rs3936840	0	3936840	regulatory_region_variant	TRUE	0.3425	4e-12	11.397940008672037	NA	0.02698156	[0.019-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3425	NA	0.02698156
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q32.31	14	102615129	RCOR1	RCOR1	NA	NA	ENSG00000089902	NA	NA	rs11382616-GC	rs11382616	0	11382616	intron_variant	FALSE	0.7052	6e-26	25.221848749616356	NA	0.04264941	[0.035-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7052	NA	0.04264941
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	14q32.32	14	103105359	EXOC3L4	EXOC3L4	NA	NA	ENSG00000205436	NA	NA	rs765807623-CTG	rs765807623	1	56105443	intron_variant	FALSE	0.2495	7e-9	8.154901959985743	NA	0.02500223	[0.017-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2495	NA	0.02500223
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	15q14	15	39002671	RP11-624L4.1	LINC02694	NA	NA	ENSG00000175779	NA	NA	rs34120329-C	rs34120329	0	34120329	intron_variant	FALSE	0.4407	3e-15	14.522878745280337	NA	0.02935467	[0.022-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4407	NA	0.02935467
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	15q15.3	15	43528519	MAP1A	MAP1A	NA	NA	ENSG00000166963	NA	NA	rs55707100-T	rs55707100	0	55707100	missense_variant	FALSE	0.0261	2e-26	25.69897000433602	NA	0.1223192	[0.1-0.145] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0261	NA	0.1223192
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	15q24.3	15	76973710	RN7SL278P	RCN2 - RN7SL278P	ENSG00000117906	ENSG00000243365	NA	19317	3205	rs62027291-A	rs62027291	0	62027291	regulatory_region_variant	TRUE	0.1628	6e-9	8.221848749616356	NA	0.02916964	[0.019-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1628	NA	0.02916964
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	9q33.2	9	122993292	RABGAP1	RABGAP1	NA	NA	ENSG00000011454	NA	NA	rs10818775-C	rs10818775	0	10818775	intron_variant	FALSE	NA	2e-12	11.698970004336019	NA	0.263	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p11.2	11	45211922	PRDM11	PRDM11	NA	NA	ENSG00000019485	NA	NA	rs10838433-G	rs10838433	0	10838433	intron_variant	FALSE	NA	5e-12	11.301029995663981	NA	0.195	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q22	12	93786840	CRADD	CRADD	NA	NA	ENSG00000169372	NA	NA	rs10859580-A	rs10859580	0	10859580	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.143	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q24.3	11	130396222	NR	ZBTB44-DT	NA	NA	ENSG00000175773	NA	NA	rs10894192-T	rs10894192	0	10894192	intron_variant	FALSE	NA	6e-62	61.221848749616356	NA	0.443	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6p21.1	6	43312975	CRIP3, ZNF318	ZNF318	NA	NA	ENSG00000171467	NA	NA	rs10948071-C	rs10948071	0	10948071	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.121	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8p11.21	8	42494067	SLC20A2	SLC20A2	NA	NA	ENSG00000168575	NA	NA	rs10958717-G	rs10958717	0	10958717	intron_variant	FALSE	NA	1e-10	10	NA	0.168	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10p11.22	10	31123632	ZNF438, ZEB1-AS1	ZNF438 - LINC02664	ENSG00000183621	ENSG00000272381	NA	91695	64083	rs11008355-G	rs11008355	0	11008355	intron_variant	TRUE	NA	1e-8	8	NA	0.168	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q21.33	12	89632685	NR	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs11105352-G	rs11105352	0	11105352	intron_variant	FALSE	NA	3e-24	23.522878745280337	NA	0.351	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q24.3	11	130403335	ZBTB44, ADAMTS8	ZBTB44-DT	NA	NA	ENSG00000175773	NA	NA	rs11222084-A	rs11222084	0	11222084	non_coding_transcript_exon_variant	FALSE	NA	8e-69	68.09691001300806	NA	0.478	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q25	11	130909173	SNX19	SNX19	NA	NA	ENSG00000120451	NA	NA	rs11222386-G	rs11222386	0	11222386	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.178	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q15.1	15	41042016	INO80	INO80	NA	NA	ENSG00000128908	NA	NA	rs112925537-A	rs112925537	0	112925537	intron_variant	FALSE	NA	8e-6	5.096910013008056	NA	0.204	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5p15.2	5	12780591	TAG	LINC01194	NA	NA	ENSG00000248131	NA	NA	rs114053299-A	rs114053299	0	114053299	intron_variant	FALSE	NA	5e-8	7.301029995663981	NA	6.487	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q33.2	2	203289954	CYP20A1	CYP20A1	NA	NA	ENSG00000119004	NA	NA	rs114407963-A	rs114407963	0	114407963	intron_variant	FALSE	NA	3e-9	8.522878745280337	NA	0.234	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q31.3	5	143154092	ARHGAP26	ARHGAP26	NA	NA	ENSG00000145819	NA	NA	rs114534-G	rs114534	0	114534	intron_variant	FALSE	NA	2e-9	8.698970004336019	NA	0.154	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p22.1	3	41841413	NR	ULK4	NA	NA	ENSG00000168038	NA	NA	rs114714860-G	rs114714860	0	114714860	intron_variant	FALSE	NA	4e-46	45.39794000867204	NA	0.474	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17q21.31	17	46121924	KANSL1	KANSL1, KANSL1, KANSL1	NA	NA	ENSG00000120071, ENSG00000275867, ENSG00000278458	NA	NA	rs115231027-T	rs115231027	1	4792830	intron_variant	FALSE	NA	3e-8	7.522878745280337	NA	0.242	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q22.33	15	67167671	SMAD3	SMAD3	NA	NA	ENSG00000166949	NA	NA	rs11638064-G	rs11638064	0	11638064	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.168	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q37.3	2	237315312	COPS8, COL6A3	NA - COL6A3	NA	ENSG00000163359	NA	NA	8691	rs11677932-G	rs11677932	0	11677932	TF_binding_site_variant	TRUE	NA	5e-8	7.301029995663981	NA	0.151	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p21	2	46136197	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs11690961-A	rs11690961	0	11690961	intron_variant	FALSE	NA	1e-14	14	NA	0.313	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	21q22.11	21	32416033	FAM176C	CFAP298-TCP10L, EVA1C	NA	NA	ENSG00000265590, ENSG00000166979	NA	NA	rs11701033-C	rs11701033	0	11701033	intron_variant	FALSE	NA	6e-8	7.221848749616356	NA	0.178	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q23	3	142898511	PCOLCE2, LOC100507389	PCOLCE2 - PAQR9	ENSG00000163710	ENSG00000188582	NA	9305	50653	rs11708647-G	rs11708647	0	11708647	intergenic_variant	TRUE	NA	4e-11	10.397940008672037	NA	0.178	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q23.3	11	118328710	CD3E, CD3D	CD3E - CD3D	ENSG00000198851	ENSG00000167286	NA	12535	10365	rs117204111-G	rs117204111	0	117204111	intergenic_variant	TRUE	NA	3e-8	7.522878745280337	NA	0.491	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q12	4	53936138	LNX1-AS2, RPL21P44	NA - RPL21P44	NA	ENSG00000229585	NA	NA	50449	rs11725861-A	rs11725861	0	11725861	intron_variant	TRUE	NA	8e-23	22.096910013008056	NA	0.51	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5p13.3	5	32814922	NPR3, LOC340113	NPR3 - NA	ENSG00000113389	NA	NA	23198	NA	rs1173771-A	rs1173771	0	1173771	regulatory_region_variant	TRUE	NA	1e-21	21	NA	0.246	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	21q22.2	21	38611524	ERG	ERG	NA	NA	ENSG00000157554	NA	NA	rs117870289-C	rs117870289	0	117870289	intron_variant	FALSE	NA	2e-9	8.698970004336019	NA	0.732	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	17q11.2	17	30998606	NA	RNF135	NA	NA	ENSG00000181481	NA	NA	rs79533578-?	rs79533578	0	79533578	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(MLM)	0.5676763	[0.33-0.81] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	14q24.3	14	77289119	NA	POMT2	NA	NA	ENSG00000009830	NA	NA	rs142996120-?	rs142996120	0	142996120	intron_variant	FALSE	NR	3e-6	5.522878745280337	(MLM)	0.702981	[0.41-1] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	17q24.3	17	71726064	NA	NA	NA	NA	NA	NA	NA	rs2429928-?	rs2429928	0	2429928	intron_variant	TRUE	NR	4e-6	5.3979400086720375	(MLM)	0.7148641	[0.41-1.02] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	5q35.1	5	170352321	NA	LINC01366 - KCNIP1	ENSG00000235172	ENSG00000182132	NA	16813	1166	rs76131026-G	rs76131026	0	76131026	intergenic_variant	TRUE	NR	1e-8	8	(GLM)	10.692	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	10q21.3	10	66162055	NA	CTNNA3	NA	NA	ENSG00000183230	NA	NA	rs200868329-AT	rs200868329	0	200868329	intron_variant	FALSE	NR	3e-6	5.522878745280337	(GLM)	7.5455	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	chr12:106657179-A	chr12:106657179	0	NA	NA	TRUE	NR	5e-6	5.301029995663981	(GLM)	7.002	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	13q14.11	13	44105194	NA	LINC00390	NA	NA	ENSG00000226519	NA	NA	rs191581512-G	rs191581512	0	191581512	non_coding_transcript_exon_variant	FALSE	NR	6e-8	7.221848749616356	(GLM)	6.736	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	22q13.33	22	49963977	NA	PIM3	NA	NA	ENSG00000198355	NA	NA	rs117325373-G	rs117325373	0	117325373	3_prime_UTR_variant	FALSE	NR	2e-6	5.698970004336019	(GLM)	6.3469	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	3q26.2	3	168747556	NA	EGFEM1P	NA	NA	ENSG00000206120	NA	NA	rs115449435-T	rs115449435	0	115449435	intron_variant	FALSE	NR	7e-6	5.154901959985743	(GLM)	6.1478	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	1p32.3	1	55180186	NA	USP24	NA	NA	ENSG00000162402	NA	NA	rs113353280-A	rs113353280	0	113353280	intron_variant	FALSE	NR	8e-6	5.096910013008056	(GLM)	5.8417	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	4q26	4	116607403	NA	ACTN4P1 - NA	ENSG00000213493	NA	NA	7792	NA	rs76540759-G	rs76540759	0	76540759	intergenic_variant	TRUE	NR	9e-6	5.045757490560675	(GLM)	5.6127	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	1p22.2	1	90109901	NA	ZNF326 - NA	ENSG00000162664	NA	NA	74368	NA	rs146460178-C	rs146460178	0	146460178	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	(GLM)	5.2383	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (positive Marder score)	1,390 European ancestry cases	NA	3q26.2	3	168633460	NA	EGFEM1P	NA	NA	ENSG00000206120	NA	NA	rs76289741-A	rs76289741	0	76289741	intron_variant	FALSE	NR	8e-6	5.096910013008056	(GLM)	5.1717	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004040	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	2p16.1	2	59725711	NA	RNA5SP94 - NA	ENSG00000252726	NA	NA	30842	NA	rs6545747-?	rs6545747	0	6545747	intron_variant	TRUE	NR	6e-6	5.221848749616356	(MLM)	0.1756764	[0.1-0.251] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	9q34.3	9	135598751	NA	PAEPP1 - GLT6D1	ENSG00000224045	ENSG00000204007	NA	6776	24897	rs7859245-?	rs7859245	0	7859245	intergenic_variant	TRUE	NR	8e-6	5.096910013008056	(MLM)	0.1832648	[0.1-0.26] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	10p11.22	10	33256536	NA	NRP1	NA	NA	ENSG00000099250	NA	NA	rs10827221-?	rs10827221	0	10827221	intron_variant	FALSE	NR	8e-6	5.096910013008056	(MLM)	0.1877251	[0.11-0.27] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	8p22	8	18600936	NA	PSD3	NA	NA	ENSG00000156011	NA	NA	rs2634458-?	rs2634458	0	2634458	intron_variant	FALSE	NR	7e-6	5.154901959985743	(MLM)	0.4892784	[0.28-0.7] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	10q21.1	10	56434080	NA	ZWINT - NA	ENSG00000122952	NA	NA	72807	NA	rs61857276-?	rs61857276	0	61857276	intergenic_variant	TRUE	NR	1e-7	7	(MLM)	0.7002314	[0.44-0.96] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	10q21.1	10	56294881	NA	NA - ZWINT	NA	ENSG00000122952	NA	NA	62346	rs61854820-?	rs61854820	0	61854820	intergenic_variant	TRUE	NR	6e-8	7.221848749616356	(MLM)	0.724535	[0.46-0.99] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	10q21.1	10	56074184	NA	NA	NA	NA	NA	NA	NA	rs77217161-?	rs77217161	0	77217161	intergenic_variant	TRUE	NR	9e-7	6.045757490560675	(MLM)	0.6896701	[0.42-0.96] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	11p15.3	11	12026851	NA	DKK3 - LINC02547	ENSG00000050165	ENSG00000254486	NA	17082	4024	rs923806-?	rs923806	0	923806	regulatory_region_variant	TRUE	NR	8e-6	5.096910013008056	(MLM)	0.6283593	[0.35-0.9] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	13q14.11	13	43866062	NA	CCDC122	NA	NA	ENSG00000151773	NA	NA	rs78547569-?	rs78547569	0	78547569	intron_variant	FALSE	NR	5e-6	5.301029995663981	(MLM)	0.6972073	[0.4-1] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	11q24.1	11	122490175	NA	MIR100HG	NA	NA	ENSG00000255248	NA	NA	rs117752187-G	rs117752187	0	117752187	intron_variant	FALSE	NR	6e-11	10.221848749616356	(GLM)	7.9991	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	8p22	8	15615416	NA	TUSC3	NA	NA	ENSG00000104723	NA	NA	rs76830538-C	rs76830538	0	76830538	intron_variant	FALSE	NR	2e-8	7.698970004336019	(GLM)	4.4144	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	8p22	8	15796634	NA	TUSC3 - PPM1AP1	ENSG00000104723	ENSG00000250483	NA	29985	9515	rs117019455-G	rs117019455	0	117019455	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	(GLM)	4.0451	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	5q35.1	5	170389767	NA	KCNIP1, KCNIP1-OT1	NA	NA	ENSG00000182132, ENSG00000253647	NA	NA	rs75070487-G	rs75070487	0	75070487	intron_variant	FALSE	NR	2e-7	6.698970004336019	(GLM)	4.4176	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	8q24.13	8	124967335	NA	LINC00964 - ZNF572	ENSG00000249816	ENSG00000180938	NA	4804	5960	rs2382999-G	rs2382999	0	2382999	regulatory_region_variant	TRUE	NR	3e-7	6.522878745280337	(GLM)	1.8534	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	16p13.3	16	6990147	NA	RBFOX1	NA	NA	ENSG00000078328	NA	NA	rs188803409-A	rs188803409	0	188803409	intron_variant	FALSE	NR	3e-7	6.522878745280337	(GLM)	7.2424	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	11q24.1	11	123278215	NA	CLMP - U8	ENSG00000166250	ENSG00000212594	NA	82967	23175	rs79862545-C	rs79862545	0	79862545	intergenic_variant	TRUE	NR	3e-7	6.522878745280337	(GLM)	6.1924	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	8p23.1	8	11008861	NA	XKR6	NA	NA	ENSG00000171044	NA	NA	rs149776388-C	rs149776388	0	149776388	intron_variant	FALSE	NR	5e-7	6.301029995663981	(GLM)	6.7037	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	9q34.3	9	138076309	NA	CACNA1B	NA	NA	ENSG00000148408	NA	NA	rs7036881-C	rs7036881	0	7036881	intron_variant	FALSE	NR	7e-7	6.154901959985743	(GLM)	4.5047	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	13q14.11	13	43983531	NA	NRAD1	NA	NA	ENSG00000233725	NA	NA	rs73177327-C	rs73177327	0	73177327	intron_variant	FALSE	NR	7e-7	6.154901959985743	(GLM)	3.781	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	1p34.3	1	36447523	NA	OSCP1	NA	NA	ENSG00000116885	NA	NA	rs138707712-T	rs138707712	0	138707712	intron_variant	FALSE	NR	7e-7	6.154901959985743	(GLM)	4.7564	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	9p22.2	9	17878240	NA	SH3GL2 - ADAMTSL1	ENSG00000107295	ENSG00000178031	NA	81116	28323	rs141473550-A	rs141473550	0	141473550	intergenic_variant	TRUE	NR	9e-7	6.045757490560675	(GLM)	4.864	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	6q26	6	161931643	NA	PRKN	NA	NA	ENSG00000185345	NA	NA	rs117673608-G	rs117673608	0	117673608	intron_variant	FALSE	NR	1e-6	6	(GLM)	6.9628	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	11q23.3	11	119793235	NA	NECTIN1 - NA	ENSG00000110400	NA	NA	64035	NA	rs73006788-C	rs73006788	0	73006788	intergenic_variant	TRUE	NR	1e-6	6	(GLM)	3.4802	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	9q34.3	9	135600269	NA	PAEPP1 - GLT6D1	ENSG00000224045	ENSG00000204007	NA	8294	23379	rs12001041-A	rs12001041	0	12001041	intergenic_variant	TRUE	NR	1e-6	6	(GLM)	1.2081	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	13q14.11	13	43857773	NA	CCDC122	NA	NA	ENSG00000151773	NA	NA	rs182333180-C	rs182333180	0	182333180	intron_variant	FALSE	NR	1e-6	6	(GLM)	3.0708	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	7p11.2	7	57356326	NA	NA - MIR3147	NA	ENSG00000266168	NA	NA	48699	rs180968789-T	rs180968789	1	113976759	intergenic_variant	TRUE	NR	1e-6	6	(GLM)	3.8855	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	5q13.3	5	76459601	NA	IQGAP2	NA	NA	ENSG00000145703	NA	NA	rs150202118-G	rs150202118	0	150202118	intron_variant	FALSE	NR	1e-6	6	(GLM)	7.3719	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	8q24.13	8	125236380	NA	NSMCE2	NA	NA	ENSG00000156831	NA	NA	rs201447509-ATC	rs201447509	0	201447509	intron_variant	FALSE	NR	1e-6	6	(GLM)	1.8871	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	15q26.2	15	96536103	NA	Metazoa_SRP - NA	ENSG00000278007	NA	NA	39641	NA	rs2083117-G	rs2083117	0	2083117	regulatory_region_variant	TRUE	NR	1e-6	6	(GLM)	2.1099	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	11q24.2	11	127546637	NA	NA	NA	NA	NA	NA	NA	rs147237795-G	rs147237795	0	147237795	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(GLM)	4.1116	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	8p22	8	14416309	NA	SGCZ	NA	NA	ENSG00000185053	NA	NA	rs116939006-C	rs116939006	0	116939006	intron_variant	FALSE	NR	2e-6	5.698970004336019	(GLM)	3.5749	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	2q11.2	2	99936050	NA	AFF3	NA	NA	ENSG00000144218	NA	NA	rs28425639-T	rs28425639	0	28425639	intron_variant	FALSE	NR	2e-6	5.698970004336019	(GLM)	3.0464	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	9q34.3	9	137974654	NA	CACNA1B	NA	NA	ENSG00000148408	NA	NA	rs78178087-G	rs78178087	0	78178087	intron_variant	FALSE	NR	2e-6	5.698970004336019	(GLM)	3.9925	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	8q24.13	8	125516480	NA	TRIB1 - NA	ENSG00000173334	NA	NA	78077	NA	rs78309295-A	rs78309295	0	78309295	intron_variant	TRUE	NR	2e-6	5.698970004336019	(GLM)	6.5925	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	20q12	20	42702075	NA	PTPRT	NA	NA	ENSG00000196090	NA	NA	rs79886049-A	rs79886049	0	79886049	intron_variant	FALSE	NR	2e-6	5.698970004336019	(GLM)	2.8136	[NR] unit increase	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	17q22	17	54257841	NA	NA	NA	NA	NA	NA	NA	rs79851935-T	rs79851935	0	79851935	intron_variant	TRUE	NR	2e-6	5.698970004336019	(GLM)	5.7487	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27846195	Li Q	2016-11-11	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/27846195	Genome-wide association study of paliperidone efficacy.	Response to paliperidone in schizophrenia (negative Marder score)	1,390 European ancestry cases	NA	13q14.11	13	44105194	NA	LINC00390	NA	NA	ENSG00000226519	NA	NA	rs191581512-G	rs191581512	0	191581512	non_coding_transcript_exon_variant	FALSE	NR	2e-6	5.698970004336019	(GLM)	4.7236	[NR] unit decrease	Illumina [~ 9000000] (imputed)	N	response to paliperidone, schizophrenia symptom severity measurement	http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927	GCST004041	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	4p15.2	4	25112979	LGI2, SEPSECS	LGI2 - SEPSECS	ENSG00000153012	ENSG00000109618	NA	82033	7035	rs10939037-?	rs10939037	0	10939037	regulatory_region_variant	TRUE	NR	1e-10	10	NA	1.0548522	[1.04-1.07]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0548522	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	12q24.12	12	111446804	SH2B3	SH2B3, ATXN2	NA	NA	ENSG00000111252, ENSG00000204842	NA	NA	rs3184504-?	rs3184504	0	3184504	missense_variant	FALSE	NR	3e-10	9.522878745280337	NA	1.052	[1.036-1.069]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.052	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	4q21.1	4	77519271	CXCL13	CXCL13	NA	NA	ENSG00000156234	NA	NA	rs7685785-?	rs7685785	0	7685785	intron_variant	FALSE	NR	5e-10	9.301029995663981	NA	1.0881393	[1.06-1.12]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0881393	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	7q31.2	7	115304865	MDFIC, TFEC	LINC01392 - NA	ENSG00000233607	NA	NA	73510	NA	rs2023703-?	rs2023703	0	2023703	intergenic_variant	TRUE	NR	8e-10	9.096910013008056	NA	1.055	[1.037-1.073]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.055	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	19p13.2	19	8679648	ADAMTS10, ACTL9	NFILZ - ACTL9	ENSG00000268480	ENSG00000181786	NA	1940	17752	rs2918308-?	rs2918308	0	2918308	intergenic_variant	TRUE	NR	1e-9	9	NA	1.0706638	[1.05-1.09]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0706638	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	17p13.3	17	2825954	RAP1GAP2	RAP1GAP2	NA	NA	ENSG00000132359	NA	NA	rs67968065-?	rs67968065	0	67968065	intron_variant	FALSE	NR	2e-9	8.698970004336019	NA	1.0515248	[1.03-1.07]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0515248	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	21q22.11	21	33680691	ITSN1	ITSN1	NA	NA	ENSG00000205726	NA	NA	rs200746495-?	rs200746495	0	200746495	intron_variant	FALSE	NR	4e-9	8.397940008672037	NA	1.0752687	[1.05-1.1]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0752687	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	2q33.3	2	206444237	ADAM23	ADAM23	NA	NA	ENSG00000114948	NA	NA	rs1448903-?	rs1448903	0	1448903	intron_variant	FALSE	NR	5e-9	8.301029995663981	NA	1.085	[1.056-1.115]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.085	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	1p36.23	1	8834287	RERE, ENO1	RERE	NA	NA	ENSG00000142599	NA	NA	rs12068123-?	rs12068123	0	12068123	intron_variant	FALSE	NR	6e-9	8.221848749616356	NA	1.049	[1.032-1.066]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.049	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	11p15.4	11	8735309	ST5	DENND2B	NA	NA	ENSG00000166444	NA	NA	rs11042055-?	rs11042055	0	11042055	intron_variant	FALSE	NR	7e-9	8.154901959985743	NA	1.048218	[1.03-1.06]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.048218	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	20q13.33	20	63975264	SAMD10	SAMD10	NA	NA	ENSG00000130590	NA	NA	rs41278232-?	rs41278232	0	41278232	3_prime_UTR_variant	FALSE	NR	8e-9	8.096910013008056	NA	1.078	[1.051-1.107]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.078	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	9q34.2	9	133279427	ABO, SURF6	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	3403	58301	rs635634-?	rs635634	0	635634	intergenic_variant	TRUE	NR	9e-9	8.045757490560675	NA	1.06	[1.039-1.081]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.06	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	17q11.2	17	28531377	FOXN1	FOXN1	NA	NA	ENSG00000109101	NA	NA	rs62066768-?	rs62066768	0	62066768	intron_variant	FALSE	NR	1e-8	8	NA	1.0893246	[1.06-1.12]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0893246	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	6q23.3	6	137682685	OLIG3, TNFAIP3	NA - LINC02539	NA	ENSG00000234956	NA	NA	47485	rs11757201-?	rs11757201	0	11757201	intron_variant	TRUE	NR	3e-8	7.522878745280337	NA	1.0570824	[1.04-1.08]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0570824	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	6p21.31	6	34227400	GRM4, HMGA1	CYCSP55 - HMGA1	ENSG00000214810	ENSG00000137309	NA	7334	9473	rs201220830-?	rs201220830	0	201220830	regulatory_region_variant	TRUE	NR	4e-8	7.3979400086720375	NA	1.1135857	[1.07-1.16]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.1135857	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	16p11.2	16	30145077	MAPK3, CORO1A	MAPK3 - CORO1A	ENSG00000102882	ENSG00000102879	NA	21571	37750	rs12931792-?	rs12931792	0	12931792	intergenic_variant	TRUE	NR	4e-8	7.3979400086720375	NA	1.057	[1.036-1.078]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.057	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	7q31.2	7	117277191	WNT2	WNT2	NA	NA	ENSG00000105989	NA	NA	rs200608253-?	rs200608253	0	200608253	3_prime_UTR_variant	FALSE	NR	4e-8	7.3979400086720375	NA	1.046	[1.029-1.063]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.046	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	22q11.21	22	19765420	TBX1	TBX1	NA	NA	ENSG00000184058	NA	NA	rs41298830-?	rs41298830	0	41298830	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	1.0559661	[1.04-1.08]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0559661	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Monobrow	69,284 European ancestry individuals	NA	2q36.1	2	222229770	PAX3	PAX3	NA	NA	ENSG00000135903	NA	NA	rs2053316-?	rs2053316	0	2053316	intron_variant	FALSE	NR	8e-104	103.09691001300806	NA	0.149	[0.135-0.162] unit increase	Illumina [12039491] (imputed)	N	synophrys measurement	http://www.ebi.ac.uk/efo/EFO_0007906	GCST003996	Genome-wide genotyping array	NA	NA	0.149
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Monobrow	69,284 European ancestry individuals	NA	9p24.3	9	1121353	DMRT2, SMARCA2	DMRT2 - RPS27AP14	ENSG00000173253	ENSG00000236594	NA	63801	43061	rs7861975-?	rs7861975	0	7861975	intergenic_variant	TRUE	NR	4e-62	61.39794000867204	NA	0.064	[0.056-0.071] unit increase	Illumina [12039491] (imputed)	N	synophrys measurement	http://www.ebi.ac.uk/efo/EFO_0007906	GCST003996	Genome-wide genotyping array	NA	NA	0.064
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Monobrow	69,284 European ancestry individuals	NA	5p13.2	5	33951588	SLC45A2	SLC45A2, SLC45A2	NA	NA	ENSG00000164175, ENSG00000281919	NA	NA	rs16891982-?	rs16891982	0	16891982	missense_variant	FALSE	NR	7e-48	47.15490195998574	NA	0.148	[0.168-0.128] unit decrease	Illumina [12039491] (imputed)	N	synophrys measurement	http://www.ebi.ac.uk/efo/EFO_0007906	GCST003996	Genome-wide genotyping array	NA	NA	0.148
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Monobrow	69,284 European ancestry individuals	NA	15q13.1	15	28165345	HERC2	HERC2, HERC2	NA	NA	ENSG00000276802, ENSG00000128731	NA	NA	rs12916300-?	rs12916300	0	12916300	intron_variant	FALSE	NR	5e-47	46.30102999566398	NA	0.067	[0.077-0.058] unit decrease	Illumina [12039491] (imputed)	N	synophrys measurement	http://www.ebi.ac.uk/efo/EFO_0007906	GCST003996	Genome-wide genotyping array	NA	NA	0.067
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Monobrow	69,284 European ancestry individuals	NA	1p32.3	1	53729345	GLIS1	GLIS1	NA	NA	ENSG00000174332	NA	NA	rs702490-?	rs702490	0	702490	intron_variant	FALSE	NR	2e-45	44.69897000433602	NA	0.055	[0.063-0.047] unit decrease	Illumina [12039491] (imputed)	N	synophrys measurement	http://www.ebi.ac.uk/efo/EFO_0007906	GCST003996	Genome-wide genotyping array	NA	NA	0.055
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Monobrow	69,284 European ancestry individuals	NA	Xq13.1	X	69782010	EDA	EDA	NA	NA	ENSG00000158813	NA	NA	rs2804362-?	rs2804362	0	2804362	intron_variant	FALSE	NR	9e-36	35.045757490560675	NA	0.037	[0.043-0.031] unit decrease	Illumina [12039491] (imputed)	N	synophrys measurement	http://www.ebi.ac.uk/efo/EFO_0007906	GCST003996	Genome-wide genotyping array	NA	NA	0.037
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Monobrow	69,284 European ancestry individuals	NA	5q13.2	5	73263512	TMEM174, FOXD1	TMEM174 - LINC02230	ENSG00000164325	ENSG00000251543	NA	88369	74394	rs6881396-?	rs6881396	0	6881396	intron_variant	TRUE	NR	7e-35	34.15490195998574	NA	0.046	[0.054-0.039] unit decrease	Illumina [12039491] (imputed)	N	synophrys measurement	http://www.ebi.ac.uk/efo/EFO_0007906	GCST003996	Genome-wide genotyping array	NA	NA	0.046
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	2p13.1	2	73312916	EGR4, ALMS1	RNU6-111P - RPSAP28	ENSG00000252988	ENSG00000214484	NA	14129	57103	rs35327298-?	rs35327298	0	35327298	intergenic_variant	TRUE	NR	1e-8	8	NA	0.159	[­0.214-0.105] unit decrease	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.159
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	2q24.1	2	155765213	KCNJ3, NR4A2	NA	NA	NA	NA	NA	NA	rs142058842-?	rs142058842	0	142058842	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	NA	0.04	[0.026-0.054] unit increase	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.04
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	9q31.3	9	111518588	KIAA0368, ZNF483	ECPAS - ZNF483	ENSG00000136813	ENSG00000173258	NA	33843	6571	rs10980922-?	rs10980922	0	10980922	intergenic_variant	TRUE	NR	1e-7	7	NA	0.052	[0.033-0.072] unit increase	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.052
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	6p22.3	6	19076186	RNF144B, ID4	NA	NA	NA	NA	NA	NA	rs9350100-?	rs9350100	0	9350100	intergenic_variant	TRUE	NR	1e-7	7	NA	0.036	[­0.049-0.023] unit decrease	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.036
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	3p21.31	3	50396536	CACNA2D2	CACNA2D2	NA	NA	ENSG00000007402	NA	NA	rs2282752-?	rs2282752	0	2282752	intron_variant	FALSE	NR	4e-7	6.3979400086720375	NA	0.038	[­0.053-0.024] unit decrease	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.038
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	1q32.1	1	199888454	NR5A2	RNU6-778P - NA	ENSG00000200139	NA	NA	193	NA	rs6681737-?	rs6681737	0	6681737	intergenic_variant	TRUE	NR	6e-7	6.221848749616356	NA	0.027	[0.017-0.038] unit increase	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.027
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Age at voice drop	55,871 European ancestry individuals	NA	7p21.3	7	11473250	THSD7A	THSD7A	NA	NA	ENSG00000005108	NA	NA	rs148707903-?	rs148707903	0	148707903	intron_variant	FALSE	NR	9e-7	6.045757490560675	NA	0.471	[0.283-0.659] unit increase	Illumina [12039491]	N	age at voice drop	http://www.ebi.ac.uk/efo/EFO_0007888	GCST003994	Genome-wide genotyping array	NA	NA	0.471
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	12p13.31	12	6384185	LTBR	LTBR	NA	NA	ENSG00000111321	NA	NA	rs10849448-?	rs10849448	0	10849448	5_prime_UTR_variant	FALSE	NR	2e-35	34.69897000433602	NA	1.1273957	[1.11-1.15]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.1273957	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	22q12.2	22	29928666	MTMR3	MTMR3	NA	NA	ENSG00000100330	NA	NA	rs201112509-?	rs201112509	0	201112509	intron_variant	FALSE	NR	3e-34	33.52287874528034	NA	1.12	[1.100-1.141]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.12	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	17p11.2	17	16948873	TNFRSF13B	TNFRSF13B	NA	NA	ENSG00000240505	NA	NA	rs34557412-?	rs34557412	0	34557412	missense_variant	FALSE	NR	3e-21	20.522878745280337	NA	1.595	[1.449-1.755]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.595	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	6p21.33	6	31354913	MICA, HLA-C	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B, HLA-B	NA	NA	ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000232126, ENSG00000224608, ENSG00000206450	NA	NA	rs41543314-?	rs41543314	0	41543314	non_coding_transcript_exon_variant	FALSE	NR	5e-21	20.30102999566398	NA	1.232	[1.180-1.286]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.232	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	13q33.3	13	108308033	TNFSF13B	TNFSF13B	NA	NA	ENSG00000102524	NA	NA	rs200748895-?	rs200748895	0	200748895	3_prime_UTR_variant	FALSE	NR	1e-17	17	NA	1.2594458	[1.19-1.33]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.2594458	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	7p12.3	7	46054491	IGFBP3	TTC4P1 - ZNF619P1	ENSG00000221971	ENSG00000224547	NA	53713	90446	rs80077929-?	rs80077929	0	80077929	regulatory_region_variant	TRUE	NR	2e-15	14.698970004336019	NA	1.111	[1.083-1.140]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.111	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	4q24	4	102540881	NFKB1	NFKB1	NA	NA	ENSG00000109320	NA	NA	rs230523-?	rs230523	0	230523	intron_variant	FALSE	NR	5e-14	13.301029995663981	NA	1.067	[1.050-1.086]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.067	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	7p15.2	7	27098564	HOXA1, HOXA2	HOTAIRM1	NA	NA	ENSG00000233429	NA	NA	rs6668-?	rs6668	0	6668	intron_variant	FALSE	NR	2e-13	12.698970004336019	NA	1.065	[1.047-1.083]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.065	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	14q21.1	14	37555893	MIPOL1, FOXA1	MIPOL1 - FOXA1	ENSG00000151338	ENSG00000129514	NA	3532	33659	rs148131694-?	rs148131694	0	148131694	intergenic_variant	TRUE	NR	8e-13	12.096910013008056	NA	1.066	[1.047-1.084]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.066	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	4q24	4	105230485	TET2	TET2	NA	NA	ENSG00000168769	NA	NA	rs1391439-?	rs1391439	0	1391439	intron_variant	FALSE	NR	3e-12	11.522878745280337	NA	1.06	[1.043-1.077]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.06	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	2p14	2	65335729	SPRED2	SPRED2	NA	NA	ENSG00000198369	NA	NA	rs201473667-?	rs201473667	0	201473667	intron_variant	FALSE	NR	5e-12	11.301029995663981	NA	1.0582011	[1.04-1.08]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0582011	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	20q13.12	20	46110780	NCOA5, CD40	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	NA	10604	7498	rs6032664-?	rs6032664	0	6032664	regulatory_region_variant	TRUE	NR	7e-12	11.154901959985743	NA	1.0649627	[1.05-1.08]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0649627	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	7p12.2	7	50269096	C7orf72, IKZF1	NA - IKZF1	NA	ENSG00000185811	NA	NA	34972	rs876037-?	rs876037	0	876037	intergenic_variant	TRUE	NR	1e-11	11	NA	1.061	[1.043-1.079]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.061	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	13q21.33	13	70005395	KLHL1	KLHL1	NA	NA	ENSG00000150361	NA	NA	rs9542155-?	rs9542155	0	9542155	intron_variant	FALSE	NR	2e-11	10.698970004336019	NA	1.06	[1.042-1.078]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.06	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	7p22.2	7	2801530	GNA12	GNA12	NA	NA	ENSG00000146535	NA	NA	rs2644312-?	rs2644312	0	2644312	intron_variant	FALSE	NR	3e-11	10.522878745280337	NA	1.061	[1.043-1.080]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.061	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	3q21.2	3	125192997	SLC12A8	SLC12A8	NA	NA	ENSG00000221955	NA	NA	rs1980080-?	rs1980080	0	1980080	intron_variant	FALSE	NR	3e-11	10.522878745280337	NA	1.059322	[1.04-1.08]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.059322	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	16p12.1	16	28319648	SBK1	SBK1	NA	NA	ENSG00000188322	NA	NA	rs141876325-?	rs141876325	0	141876325	intron_variant	FALSE	NR	5e-11	10.301029995663981	NA	1.063	[1.044-1.083]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.063	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls	NA	1q41	1	221992567	DUSP10, HHIPL2	LINC02474 - LINC01705	ENSG00000228437	ENSG00000232679	NA	7603	18258	rs12126292-?	rs12126292	0	12126292	TF_binding_site_variant	TRUE	NR	7e-11	10.154901959985743	NA	1.0869565	[1.06-1.11]	Illumina [13757430] (imputed)	N	tonsillectomy risk measurement	http://www.ebi.ac.uk/efo/EFO_0007924	GCST003995	Genome-wide genotyping array	NA	1.0869565	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related diseases, mortality and associated endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	rs765547-?	rs765547	0	765547	intergenic_variant	TRUE	NR	2e-44	43.69897000433602	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, cancer, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0000275, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0001645, http://www.ebi.ac.uk/efo/EFO_0000311, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003144, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004352	GCST004045	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related diseases, mortality and associated endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	8q24.13	8	125466108	NR	TRIB1 - NA	ENSG00000173334	NA	NA	27705	NA	rs2980853-?	rs2980853	0	2980853	regulatory_region_variant	TRUE	NR	3e-18	17.522878745280337	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, cancer, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0000275, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0001645, http://www.ebi.ac.uk/efo/EFO_0000311, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003144, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004352	GCST004045	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related diseases, mortality and associated endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	9p21.3	9	22125504	NR	CDKN2B-AS1	NA	NA	ENSG00000240498	NA	NA	rs1333049-?	rs1333049	0	1333049	intron_variant	FALSE	NR	9e-8	7.045757490560675	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, cancer, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0000275, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0001645, http://www.ebi.ac.uk/efo/EFO_0000311, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003144, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004352	GCST004045	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related diseases, mortality and associated endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	20q12	20	41147406	NR	PLCG1	NA	NA	ENSG00000124181	NA	NA	rs760762-?	rs760762	0	760762	intron_variant	FALSE	NR	7e-7	6.154901959985743	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, cancer, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0000275, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0001645, http://www.ebi.ac.uk/efo/EFO_0000311, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003144, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004352	GCST004045	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related diseases, mortality and associated endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	20q12	20	41322165	NR	ZHX3 - ADI1P1	ENSG00000174306	ENSG00000235102	NA	4434	8958	rs2866611-?	rs2866611	0	2866611	regulatory_region_variant	TRUE	NR	6e-7	6.221848749616356	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, cancer, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0000275, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0001645, http://www.ebi.ac.uk/efo/EFO_0000311, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003144, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004352	GCST004045	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related diseases, mortality and associated endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	21q22.3	21	41463567	NR	MX1	NA	NA	ENSG00000157601	NA	NA	rs460976-?	rs460976	0	460976	intron_variant	FALSE	NR	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, cancer, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0000275, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0001645, http://www.ebi.ac.uk/efo/EFO_0000311, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003144, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004352	GCST004045	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related diseases, mortality and associated endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	10p12.1	10	26969741	NR	FAM238C - ANKRD26	ENSG00000283709	ENSG00000107890	NA	25323	4052	rs7081476-?	rs7081476	0	7081476	regulatory_region_variant	TRUE	NR	5e-6	5.301029995663981	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, cancer, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0000275, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0001645, http://www.ebi.ac.uk/efo/EFO_0000311, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003144, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004352	GCST004045	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related diseases, mortality and associated endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	10q25.2	10	112996282	NR	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs4506565-?	rs4506565	0	4506565	intron_variant	FALSE	NR	8e-17	16.096910013008056	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, cancer, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0000275, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0001645, http://www.ebi.ac.uk/efo/EFO_0000311, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003144, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004352	GCST004045	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	11q12.2	11	61803311	NR	FADS1, FADS2	NA	NA	ENSG00000149485, ENSG00000134824	NA	NA	rs174547-?	rs174547	0	174547	intron_variant	FALSE	NR	1e-29	29	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	11q23.3	11	116778201	NR	ZPR1	NA	NA	ENSG00000109917	NA	NA	rs964184-?	rs964184	0	964184	3_prime_UTR_variant	FALSE	NR	3e-116	115.52287874528034	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	11q23.3	11	117037567	NR	SIK3	NA	NA	ENSG00000160584	NA	NA	rs7115242-?	rs7115242	0	7115242	intron_variant	FALSE	NR	1e-10	10	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	12q21.33	12	89656726	NR	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs12579302-?	rs12579302	0	12579302	intron_variant	FALSE	NR	3e-7	6.522878745280337	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	12q24.31	12	122479003	NR	ZCCHC8	NA	NA	ENSG00000033030	NA	NA	rs12369179-?	rs12369179	0	12369179	intron_variant	FALSE	NR	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	15q21.3	15	58435126	NR	LIPC-AS1, LIPC, ALDH1A2	NA	NA	ENSG00000259293, ENSG00000166035, ENSG00000128918	NA	NA	rs261332-?	rs261332	0	261332	non_coding_transcript_exon_variant	FALSE	NR	4e-42	41.39794000867204	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	16q12.2	16	53786615	NR	FTO	NA	NA	ENSG00000140718	NA	NA	rs9939609-?	rs9939609	0	9939609	intron_variant	FALSE	NR	2e-17	16.69897000433602	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	16q13	16	56956804	NR	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237	NA	11940	5119	rs247617-?	rs247617	0	247617	regulatory_region_variant	TRUE	NR	4e-165	164.39794000867204	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	18p11.22	18	8522684	NR	THEMIS3P - AKR1B1P6	ENSG00000229442	ENSG00000225212	NA	8835	22951	rs8082812-?	rs8082812	0	8082812	intergenic_variant	TRUE	NR	4e-8	7.3979400086720375	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	19p13.11	19	19296909	NR	SUGP1	NA	NA	ENSG00000105705	NA	NA	rs10401969-?	rs10401969	0	10401969	intron_variant	FALSE	NR	2e-11	10.698970004336019	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	19q13.32	19	44919689	NR	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855	NA	340	7115	rs4420638-?	rs4420638	0	4420638	regulatory_region_variant	TRUE	NR	2e-25	24.69897000433602	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	19q13.32	19	44744370	NR	CEACAM16-AS1 - BCL3	ENSG00000266903	ENSG00000069399	NA	19153	3335	rs4803750-?	rs4803750	0	4803750	intergenic_variant	TRUE	NR	4e-16	15.397940008672037	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	1p13.3	1	109275684	NR	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs629301-?	rs629301	0	629301	3_prime_UTR_variant	FALSE	NR	2e-51	50.69897000433602	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	2p24.1	2	21065449	NR	APOB - TDRD15	ENSG00000084674	ENSG00000218819	NA	21376	58519	rs562338-?	rs562338	0	562338	intergenic_variant	TRUE	NR	3e-25	24.522878745280337	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	2p24.1	2	21176344	NR	TDRD15 - NA	ENSG00000218819	NA	NA	31976	NA	rs478442-?	rs478442	0	478442	regulatory_region_variant	TRUE	NR	8e-21	20.096910013008056	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	2p23.3	2	27263727	NR	SLC30A3	NA	NA	ENSG00000115194	NA	NA	rs6759518-?	rs6759518	0	6759518	intron_variant	FALSE	NR	5e-7	6.301029995663981	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	2p23.3	2	27412596	NR	PPM1G - NRBP1	ENSG00000115241	ENSG00000115216	NA	3005	15194	rs1728918-?	rs1728918	0	1728918	regulatory_region_variant	TRUE	NR	5e-35	34.30102999566398	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	11q23.2	11	114169672	ZBTB16	ZBTB16	NA	NA	ENSG00000109906	NA	NA	rs77669868-G	rs77669868	0	77669868	intron_variant	FALSE	0.1717	9e-10	9.045757490560675	NA	0.02964656	[0.02-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1717	NA	0.02964656
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	11q24.1	11	122649353	intergenic	GLULP3 - UBASH3B	ENSG00000254572	ENSG00000154127	NA	34867	6369	rs144110170-A	rs144110170	0	144110170	regulatory_region_variant	TRUE	0.1238	9e-16	15.045757490560675	NA	0.0436439	[0.033-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1238	NA	0.0436439
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	12p13.33	12	642348	RP11-218M22.1, NINJ2	NINJ2, NINJ2-AS1	NA	NA	ENSG00000171840, ENSG00000177406	NA	NA	rs61916675-G	rs61916675	0	61916675	intron_variant	FALSE	0.3403	8e-9	8.096910013008056	NA	0.02185791	[0.014-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3403	NA	0.02185791
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	12p13.31	12	6384185	LTBR	LTBR	NA	NA	ENSG00000111321	NA	NA	rs10849448-G	rs10849448	0	10849448	5_prime_UTR_variant	FALSE	0.7569	4e-46	45.39794000867204	NA	0.06151777	[0.053-0.07] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.7569	NA	0.06151777
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	12p13.31	12	9747028	intergenic	CLECL1 - CD69	ENSG00000184293	ENSG00000110848	NA	13729	5458	rs10844682-C	rs10844682	0	10844682	regulatory_region_variant	TRUE	0.3414	3e-12	11.522878745280337	NA	0.02637725	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3414	NA	0.02637725
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	12p13.2	12	10447769	KLRC1	KLRC1	NA	NA	ENSG00000134545	NA	NA	rs2734442-A	rs2734442	0	2734442	intron_variant	FALSE	0.8746	1e-16	16	NA	0.04474119	[0.034-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.8746	NA	0.04474119
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	12q13.13	12	53444475	PCBP2, RP11-793H13.8, PRR13	PRR13	NA	NA	ENSG00000205352	NA	NA	rs550235164-A	rs550235164	0	550235164	intron_variant	FALSE	0.0089	1e-22	22	NA	0.2007477	[0.16-0.24] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0089	NA	0.2007477
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	12q13.13	12	54292096	RP11-968A15.8	HNRNPA1 - NFE2	ENSG00000135486	ENSG00000123405	NA	5008	15	rs35979828-T	rs35979828	0	35979828	intron_variant	TRUE	0.0704	8e-13	12.096910013008056	NA	0.04991437	[0.036-0.064] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0704	NA	0.04991437
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	12q15	12	69350234	LYZ	LYZ	NA	NA	ENSG00000090382	NA	NA	rs1800973-A	rs1800973	0	1800973	missense_variant	FALSE	0.0617	4e-46	45.39794000867204	NA	0.1056857	[0.091-0.12] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0617	NA	0.1056857
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	12q23.3	12	108326669	CMKLR1	CMKLR1	NA	NA	ENSG00000174600	NA	NA	rs4964677-C	rs4964677	0	4964677	intron_variant	FALSE	0.3896	6e-16	15.221848749616356	NA	0.02958099	[0.022-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3896	NA	0.02958099
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	12q24.12	12	111407152	SH2B3	SH2B3	NA	NA	ENSG00000111252	NA	NA	rs540639423-T	rs540639423	0	540639423	intron_variant	FALSE	0.0084	6e-12	11.221848749616356	NA	0.1450696	[0.1-0.19] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0084	NA	0.1450696
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	12q24.22	12	116401216	intergenic	NA - MIR4472-2	NA	ENSG00000264037	NA	NA	27036	rs73204034-T	rs73204034	0	73204034	regulatory_region_variant	TRUE	0.0777	4e-12	11.397940008672037	NA	0.0461222	[0.033-0.059] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0777	NA	0.0461222
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	13q12.2	13	28025777	FLT3	FLT3	NA	NA	ENSG00000122025	NA	NA	rs2491244-A	rs2491244	0	2491244	intron_variant	FALSE	0.5893	5e-25	24.30102999566398	NA	0.03747725	[0.03-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5893	NA	0.03747725
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	13q12.2	13	28029870	FLT3	FLT3	NA	NA	ENSG00000122025	NA	NA	rs76428106-C	rs76428106	0	76428106	intron_variant	FALSE	0.0146	4e-188	187.39794000867204	NA	0.4563644	[0.43-0.49] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0146	NA	0.4563644
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	13q12.2	13	28268814	PAN3	PAN3	NA	NA	ENSG00000152520	NA	NA	rs377741153-CT	rs377741153	0	377741153	intron_variant	FALSE	0.0394	4e-25	24.397940008672037	NA	0.1003137	[0.081-0.119] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0394	NA	0.1003137
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	13q14.11	13	40399886	intergenic	LINC00598	NA	NA	ENSG00000215483	NA	NA	rs77526211-A	rs77526211	0	77526211	intron_variant	FALSE	0.0319	5e-10	9.301029995663981	NA	0.06537176	[0.045-0.086] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0319	NA	0.06537176
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	13q14.11	13	40428504	intergenic	LINC00598	NA	NA	ENSG00000215483	NA	NA	rs1892548-C	rs1892548	0	1892548	intron_variant	FALSE	0.6578	3e-64	63.52287874528034	NA	0.06431439	[0.057-0.072] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.6578	NA	0.06431439
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	13q14.11	13	40642397	FOXO1	FOXO1	NA	NA	ENSG00000150907	NA	NA	rs4325427-T	rs4325427	0	4325427	intron_variant	FALSE	0.2868	1e-16	16	NA	0.03253815	[0.025-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2868	NA	0.03253815
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	13q21.33	13	71939282	intergenic	RPS10P21 - RPL18AP17	ENSG00000232881	ENSG00000227952	NA	25104	520850	rs73217470-G	rs73217470	0	73217470	intergenic_variant	TRUE	0.0476	1e-23	23	NA	0.08493428	[0.068-0.102] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0476	NA	0.08493428
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	13q33.3	13	108341146	intergenic	TNFSF13B - NA	ENSG00000102524	NA	NA	32662	NA	rs12874404-G	rs12874404	0	12874404	intron_variant	TRUE	0.0544	3e-13	12.522878745280337	NA	0.05778536	[0.042-0.073] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0544	NA	0.05778536
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	13q33.3	13	109359492	intergenic	LINC01067 - LINC00399	ENSG00000236053	ENSG00000229792	NA	47719	41204	rs9555596-C	rs9555596	0	9555596	intergenic_variant	TRUE	0.384	7e-13	12.154901959985743	NA	0.02645999	[0.019-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.384	NA	0.02645999
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	14q11.2	14	23118629	CEBPE	CEBPE	NA	NA	ENSG00000092067	NA	NA	rs141903485-T	rs141903485	0	141903485	missense_variant	FALSE	0.0087	1e-12	12	NA	0.1501399	[0.11-0.19] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0087	NA	0.1501399
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	14q11.2	14	23120140	CEBPE	CEBPE - SLC7A8	ENSG00000092067	ENSG00000092068	NA	885	5155	rs2239630-G	rs2239630	0	2239630	regulatory_region_variant	TRUE	0.5596	3e-53	52.52287874528034	NA	0.05541895	[0.048-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5596	NA	0.05541895
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	14q13.2	14	35102957	PPP2R3C, FAM177A1	FAM177A1, PPP2R3C	NA	NA	ENSG00000151327, ENSG00000092020	NA	NA	rs111778408-A	rs111778408	0	111778408	intron_variant	FALSE	0.1097	1e-10	10	NA	0.03693594	[0.026-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1097	NA	0.03693594
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	14q32.32	14	103375016	RP11-600F24.1	RPSAP5 - MARK3	ENSG00000243904	ENSG00000075413	NA	100	10361	rs375246367-C	rs375246367	1	35822385	intergenic_variant	TRUE	0.7329	3e-37	36.52287874528034	NA	0.05145047	[0.044-0.059] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.7329	NA	0.05145047
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	2p23.3	2	27518370	NR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs780094-?	rs780094	0	780094	intron_variant	FALSE	NR	8e-101	100.09691001300806	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	4q24	4	102363708	NR	SLC39A8	NA	NA	ENSG00000138821	NA	NA	rs13114738-?	rs13114738	0	13114738	intron_variant	FALSE	NR	1e-10	10	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	5q13.3	5	75329662	NR	ANKRD31 - HMGCR	ENSG00000145700	ENSG00000113161	NA	92751	6667	rs7703051-?	rs7703051	0	7703051	intron_variant	TRUE	NR	4e-12	11.397940008672037	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	5q13.3	5	75463358	NR	CERT1	NA	NA	ENSG00000113163	NA	NA	rs4704221-?	rs4704221	0	4704221	intron_variant	FALSE	NR	5e-11	10.301029995663981	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	5q13.3	5	75584065	NR	POLK	NA	NA	ENSG00000122008	NA	NA	rs5744680-?	rs5744680	0	5744680	intron_variant	FALSE	NR	6e-11	10.221848749616356	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	5q13.3	5	75741470	NR	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078	NA	24022	11100	rs9942416-?	rs9942416	0	9942416	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	7q11.23	7	73462836	NR	BAZ1B	NA	NA	ENSG00000009954	NA	NA	rs2074755-?	rs2074755	0	2074755	non_coding_transcript_exon_variant	FALSE	NR	3e-40	39.52287874528034	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	7q11.23	7	73637727	NR	MLXIPL - VPS37D	ENSG00000009950	ENSG00000176428	NA	13184	30104	rs799165-?	rs799165	0	799165	intergenic_variant	TRUE	NR	8e-19	18.096910013008056	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	8p23.1	8	9329014	NR	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	41436	42076	rs4841134-?	rs4841134	0	4841134	intron_variant	TRUE	NR	8e-6	5.096910013008056	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	rs765547-?	rs765547	0	765547	intergenic_variant	TRUE	NR	3e-51	50.52287874528034	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	8q24.13	8	125466108	NR	TRIB1 - NA	ENSG00000173334	NA	NA	27705	NA	rs2980853-?	rs2980853	0	2980853	regulatory_region_variant	TRUE	NR	2e-22	21.69897000433602	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	20q12	20	41147406	NR	PLCG1	NA	NA	ENSG00000124181	NA	NA	rs760762-?	rs760762	0	760762	intron_variant	FALSE	NR	4e-8	7.3979400086720375	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	20q12	20	41322165	NR	ZHX3 - ADI1P1	ENSG00000174306	ENSG00000235102	NA	4434	8958	rs2866611-?	rs2866611	0	2866611	regulatory_region_variant	TRUE	NR	2e-8	7.698970004336019	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	10q25.2	10	112996282	NR	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs4506565-?	rs4506565	0	4506565	intron_variant	FALSE	NR	4e-16	15.397940008672037	NA	NA	NA	Affymetrix [NR]	N	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612	GCST004046	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p36.22	1	11836799	NR	CLCN6	NA	NA	ENSG00000011021	NA	NA	rs55892892-C	rs55892892	0	55892892	intron_variant	FALSE	NA	2e-31	30.69897000433602	NA	0.993	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q21.1	4	76444738	SHROOM3	SHROOM3	NA	NA	ENSG00000138771	NA	NA	rs55940751-C	rs55940751	0	55940751	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.216	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q21.2	7	91639626	FZD1, MTERF	NA - MTERF1	NA	ENSG00000127989	NA	NA	52382	rs560276033-GTA	rs560276033	1	34583398	intron_variant	TRUE	NA	4e-6	5.3979400086720375	NA	0.472	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16q21	16	65231799	CDH11, LOC283867	LINC02126 - LINC00922	ENSG00000259847	ENSG00000261742	NA	55086	52697	rs56249585-C	rs56249585	0	56249585	intron_variant	TRUE	NA	5e-9	8.301029995663981	NA	0.373	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q22.1	4	88831125	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs57400569-G	rs57400569	0	57400569	intron_variant	FALSE	NA	7e-8	7.154901959985743	NA	0.244	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q23.2	11	113089378	NCAM1	NCAM1	NA	NA	ENSG00000149294	NA	NA	rs5794844-GT	rs5794844	0	5794844	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.355	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q13.32	20	59176062	SLMO2, ZNF831	ZNF831	NA	NA	ENSG00000124203	NA	NA	rs6015450-A	rs6015450	0	6015450	intron_variant	FALSE	NA	7e-20	19.154901959985743	NA	0.543	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p32.1	1	59197669	HSD52, MIR4711	FGGY-DT, LINC01358	NA	NA	ENSG00000224609, ENSG00000237352	NA	NA	rs60199046-A	rs60199046	0	60199046	intron_variant	FALSE	NA	3e-8	7.522878745280337	NA	0.24	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q13.12	20	44168718	JPH2	JPH2	NA	NA	ENSG00000149596	NA	NA	rs6031435-A	rs6031435	0	6031435	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.214	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q11.21	20	31581870	HM13-AS1, ID1	RNU6-384P - ID1	ENSG00000201770	ENSG00000125968	NA	678	23413	rs6060114-T	rs6060114	0	6060114	TF_binding_site_variant	TRUE	NA	2e-6	5.698970004336019	NA	0.259	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q13.33	20	64060707	TCEA2	TCEA2	NA	NA	ENSG00000171703	NA	NA	rs6090040-A	rs6090040	0	6090040	intron_variant	FALSE	NA	1e-9	9	NA	0.265	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20p12.2	20	10986566	NR	FAT1P1 - LINC02871	ENSG00000217809	ENSG00000125899	NA	97478	9727	rs6108787-T	rs6108787	0	6108787	intron_variant	TRUE	NA	3e-17	16.522878745280337	NA	0.322	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q12	20	41623190	CHD6, PTPRT	CHD6 - RNU6-1018P	ENSG00000124177	ENSG00000252386	NA	4806	61796	rs6129880-T	rs6129880	0	6129880	intergenic_variant	TRUE	NA	2e-8	7.698970004336019	NA	0.264	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p11.12	11	48902204	OR4A47, TRIM51GP	NA - TRIM51CP	NA	ENSG00000249910	NA	NA	43490	rs61448762-G	rs61448762	0	61448762	intergenic_variant	TRUE	NA	4e-9	8.397940008672037	NA	0.358	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p13	11	31799919	PAX6	PAX6	NA	NA	ENSG00000007372	NA	NA	rs61879810-A	rs61879810	0	61879810	intron_variant	FALSE	NA	7e-8	7.154901959985743	NA	0.285	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q21.3	3	128483046	GATA2	GATA2	NA	NA	ENSG00000179348	NA	NA	rs62270945-C	rs62270945	0	62270945	intron_variant	FALSE	NA	1e-6	6	NA	0.608	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q21.3	5	108767026	FER	FER	NA	NA	ENSG00000151422	NA	NA	rs62361303-C	rs62361303	0	62361303	intron_variant	FALSE	NA	6e-7	6.221848749616356	NA	0.262	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q24.3	8	142979538	CYP11B2, LOC100133669	CYP11B2 - LY6E-DT	ENSG00000179142	ENSG00000247317	NA	61695	2200	rs62524579-G	rs62524579	0	62524579	intergenic_variant	TRUE	NA	3e-10	9.522878745280337	NA	0.244	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q22.1	11	100722807	ARHGAP42	ARHGAP42	NA	NA	ENSG00000165895	NA	NA	rs633185-G	rs633185	0	633185	intron_variant	FALSE	NA	1e-31	31	NA	0.488	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	13q12.3	13	29572064	SLC7A1	SLC7A1	NA	NA	ENSG00000139514	NA	NA	rs63418562-C	rs63418562	1	9508495	intron_variant	FALSE	NA	9e-9	8.045757490560675	NA	0.312	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1q42.3	1	236162705	GPR137B	GPR137B	NA	NA	ENSG00000077585	NA	NA	rs6428947-C	rs6428947	0	6428947	intron_variant	FALSE	NA	5e-7	6.301029995663981	NA	0.253	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q32.2	2	190629685	TMEM194B, NAB1	RN7SKP179 - NAB1	ENSG00000251935	ENSG00000138386	NA	76205	17061	rs6434404-A	rs6434404	0	6434404	intron_variant	TRUE	NA	5e-13	12.301029995663981	NA	0.311	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q24.1	15	74833304	CPLX3, ULK3	CPLX3 - ULK3	ENSG00000213578	ENSG00000140474	NA	1502	2814	rs6495122-A	rs6495122	0	6495122	regulatory_region_variant	TRUE	NA	1e-16	16	NA	0.326	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q23.3	5	128532506	FBN2	FBN2	NA	NA	ENSG00000138829	NA	NA	rs6595838-G	rs6595838	0	6595838	intron_variant	FALSE	NA	2e-10	9.698970004336019	NA	0.267	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.5	11	1884062	LSP1	LSP1	NA	NA	ENSG00000130592	NA	NA	rs661348-T	rs661348	0	661348	intron_variant	FALSE	NA	2e-15	14.698970004336019	NA	0.354	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.4	11	10004305	NR	SBF2	NA	NA	ENSG00000133812	NA	NA	rs66803065-C	rs66803065	0	66803065	intron_variant	FALSE	NA	4e-19	18.397940008672037	NA	0.429	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q26	4	119588124	PDE5A	PDE5A	NA	NA	ENSG00000138735	NA	NA	rs66887589-T	rs66887589	0	66887589	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.214	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6p12.1	6	54112697	MLIP	MLIP	NA	NA	ENSG00000146147	NA	NA	rs670463-A	rs670463	0	670463	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	0.187	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p21.31	3	48156124	MAP4, CDC25A	RN7SL664P - CDC25A	ENSG00000265078	ENSG00000164045	NA	61019	1022	rs6797587-A	rs6797587	0	6797587	regulatory_region_variant	TRUE	NA	3e-16	15.522878745280337	NA	0.331	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr20:57738070-?	chr20:57738070	0	NA	NA	TRUE	NA	5e-8	7.301029995663981	NA	0.291	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr20:57738070-?	chr20:57738070	0	NA	NA	TRUE	NA	3e-6	5.522878745280337	(EA)	0.27	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr5:122699198-?	chr5:122699198	0	NA	NA	TRUE	NA	4e-11	10.397940008672037	NA	0.232	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr5:122699198-?	chr5:122699198	0	NA	NA	TRUE	NA	7e-9	8.154901959985743	(EA)	0.224	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7p12.3	7	45970501	IGFBP3, TNS3	IGFBP3 - FTLP15	ENSG00000146674	ENSG00000233952	NA	48627	27039	rs10260816-C	rs10260816	0	10260816	intron_variant	TRUE	NA	2e-7	6.698970004336019	(EA)	0.208	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7p12.3	7	45970501	IGFBP3, TNS3	IGFBP3 - FTLP15	ENSG00000146674	ENSG00000233952	NA	48627	27039	rs10260816-C	rs10260816	0	10260816	intron_variant	TRUE	NA	4e-6	5.3979400086720375	NA	0.167	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	19p13.2	19	7259335	INSR	INSR	NA	NA	ENSG00000171105	NA	NA	rs10427021-T	rs10427021	0	10427021	intron_variant	FALSE	NA	3e-9	8.522878745280337	(EA)	0.347	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	19p13.2	19	7259335	INSR	INSR	NA	NA	ENSG00000171105	NA	NA	rs10427021-T	rs10427021	0	10427021	intron_variant	FALSE	NA	9e-9	8.045757490560675	NA	0.305	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q35	2	217804009	TNS1	TNS1	NA	NA	ENSG00000079308	NA	NA	rs1063281-C	rs1063281	0	1063281	3_prime_UTR_variant	FALSE	NA	5e-6	5.301029995663981	(EA)	0.18	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q35	2	217804009	TNS1	TNS1	NA	NA	ENSG00000079308	NA	NA	rs1063281-C	rs1063281	0	1063281	3_prime_UTR_variant	FALSE	NA	5e-6	5.301029995663981	NA	0.163	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q13.12	12	50116154	COX14	COX14	NA	NA	ENSG00000178449	NA	NA	rs10747570-A	rs10747570	0	10747570	intron_variant	FALSE	NA	7e-10	9.154901959985743	(EA)	0.245	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q13.12	12	50116154	COX14	COX14	NA	NA	ENSG00000178449	NA	NA	rs10747570-A	rs10747570	0	10747570	intron_variant	FALSE	NA	2e-9	8.698970004336019	NA	0.225	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10p12.31	10	18419869	CACNB2	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs11014166-A	rs11014166	0	11014166	intron_variant	FALSE	NA	1e-8	8	(EA)	0.232	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10p12.31	10	18419869	CACNB2	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs11014166-A	rs11014166	0	11014166	intron_variant	FALSE	NA	7e-8	7.154901959985743	NA	0.204	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10p12.31	10	18448045	NR	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs11014267-G	rs11014267	0	11014267	intron_variant	FALSE	NA	3e-9	8.522878745280337	NA	0.227	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10p12.31	10	18448045	NR	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs11014267-G	rs11014267	0	11014267	intron_variant	FALSE	NA	3e-8	7.522878745280337	(EA)	0.225	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q21	11	95575690	SESN3, FAM76B	SESN3 - FAM76B	ENSG00000149212	ENSG00000077458	NA	343149	193263	rs11021221-T	rs11021221	0	11021221	intron_variant	TRUE	NA	5e-6	5.301029995663981	(EA)	0.244	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q21	11	95575690	SESN3, FAM76B	SESN3 - FAM76B	ENSG00000149212	ENSG00000077458	NA	343149	193263	rs11021221-T	rs11021221	0	11021221	intron_variant	TRUE	NA	7e-6	5.154901959985743	NA	0.223	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q21.33	12	89632685	NR	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs11105352-G	rs11105352	0	11105352	intron_variant	FALSE	NA	9e-8	7.045757490560675	NA	0.254	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q21.33	12	89632685	NR	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs11105352-G	rs11105352	0	11105352	intron_variant	FALSE	NA	1e-6	6	(EA)	0.255	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p22.1	3	41841413	NR	ULK4	NA	NA	ENSG00000168038	NA	NA	rs114714860-G	rs114714860	0	114714860	intron_variant	FALSE	NA	5e-17	16.30102999566398	NA	0.388	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p22.1	3	41841413	NR	ULK4	NA	NA	ENSG00000168038	NA	NA	rs114714860-G	rs114714860	0	114714860	intron_variant	FALSE	NA	1e-12	12	(EA)	0.367	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q33.3	5	158418394	CLINT1, EBF1	LINC02227 - NA	ENSG00000276778	NA	NA	8621	NA	rs11953630-C	rs11953630	0	11953630	intergenic_variant	TRUE	NA	7e-8	7.154901959985743	NA	0.203	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q33.3	5	158418394	CLINT1, EBF1	LINC02227 - NA	ENSG00000276778	NA	NA	8621	NA	rs11953630-C	rs11953630	0	11953630	intergenic_variant	TRUE	NA	2e-7	6.698970004336019	(EA)	0.21	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7p12.3	7	45968511	IGFBP3, TNS3	IGFBP3 - FTLP15	ENSG00000146674	ENSG00000233952	NA	46637	29029	rs11977526-G	rs11977526	0	11977526	intron_variant	TRUE	NA	9e-7	6.045757490560675	(EA)	0.198	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p36.22	1	10739520	NR	CASZ1	NA	NA	ENSG00000130940	NA	NA	rs12046278-T	rs12046278	0	12046278	intron_variant	FALSE	NA	7e-9	8.154901959985743	NA	0.235	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p36.22	1	10739520	NR	CASZ1	NA	NA	ENSG00000130940	NA	NA	rs12046278-T	rs12046278	0	12046278	intron_variant	FALSE	NA	1e-6	6	(EA)	0.218	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q21.21	4	80261400	NR	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675	NA	57071	5239	rs12509595-T	rs12509595	0	12509595	intergenic_variant	TRUE	NA	4e-24	23.397940008672037	NA	0.394	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q21.21	4	80261400	NR	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675	NA	57071	5239	rs12509595-T	rs12509595	0	12509595	intergenic_variant	TRUE	NA	2e-17	16.69897000433602	(EA)	0.363	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	16p13.3	16	4896793	PPL	PPL	NA	NA	ENSG00000118898	NA	NA	rs12596053-A	rs12596053	0	12596053	intron_variant	FALSE	NA	5e-7	6.301029995663981	(EA)	0.2	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	16p13.3	16	4896793	PPL	PPL	NA	NA	ENSG00000118898	NA	NA	rs12596053-A	rs12596053	0	12596053	intron_variant	FALSE	NA	2e-7	6.698970004336019	NA	0.188	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q33.3	5	158387220	NR	LINC02227	NA	NA	ENSG00000276778	NA	NA	rs12716337-T	rs12716337	0	12716337	intron_variant	FALSE	NA	6e-9	8.221848749616356	NA	0.211	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q33.3	5	158387220	NR	LINC02227	NA	NA	ENSG00000276778	NA	NA	rs12716337-T	rs12716337	0	12716337	intron_variant	FALSE	NA	2e-6	5.698970004336019	(EA)	0.187	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2p23.3	2	26688641	NR	RPL37P11 - KCNK3	ENSG00000225024	ENSG00000171303	NA	10131	4049	rs1275984-A	rs1275984	0	1275984	intergenic_variant	TRUE	NA	2e-22	21.69897000433602	NA	0.354	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2p23.3	2	26688641	NR	RPL37P11 - KCNK3	ENSG00000225024	ENSG00000171303	NA	10131	4049	rs1275984-A	rs1275984	0	1275984	intergenic_variant	TRUE	NA	8e-21	20.096910013008056	(EA)	0.371	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2p23.3	2	26691496	CIB4, KCNK3	RPL37P11 - KCNK3	ENSG00000225024	ENSG00000171303	NA	12986	1194	rs1275988-C	rs1275988	0	1275988	intergenic_variant	TRUE	NA	3e-22	21.522878745280337	NA	0.352	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2p23.3	2	26691496	CIB4, KCNK3	RPL37P11 - KCNK3	ENSG00000225024	ENSG00000171303	NA	12986	1194	rs1275988-C	rs1275988	0	1275988	intergenic_variant	TRUE	NA	2e-20	19.69897000433602	(EA)	0.366	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q24	4	102267552	SLC39A8	SLC39A8	NA	NA	ENSG00000138821	NA	NA	rs13107325-C	rs13107325	0	13107325	missense_variant	FALSE	NA	8e-11	10.096910013008056	(EA)	0.477	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q24	4	102267552	SLC39A8	SLC39A8	NA	NA	ENSG00000138821	NA	NA	rs13107325-C	rs13107325	0	13107325	missense_variant	FALSE	NA	4e-11	10.397940008672037	NA	0.466	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	20p12.2	20	10988382	JAG1, LOC339593	FAT1P1 - LINC02871	ENSG00000217809	ENSG00000125899	NA	99294	7911	rs1327235-A	rs1327235	0	1327235	intron_variant	TRUE	NA	3e-10	9.522878745280337	NA	0.22	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	20p12.2	20	10988382	JAG1, LOC339593	FAT1P1 - LINC02871	ENSG00000217809	ENSG00000125899	NA	99294	7911	rs1327235-A	rs1327235	0	1327235	intron_variant	TRUE	NA	1e-7	7	(EA)	0.204	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2p21	2	42851618	HAAO, ZFP36L2	CHORDC1P1 - NA	ENSG00000232202	NA	NA	24001	NA	rs13403122-C	rs13403122	0	13403122	intergenic_variant	TRUE	NA	3e-7	6.522878745280337	NA	0.209	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2p21	2	42851618	HAAO, ZFP36L2	CHORDC1P1 - NA	ENSG00000232202	NA	NA	24001	NA	rs13403122-C	rs13403122	0	13403122	intergenic_variant	TRUE	NA	1e-6	6	(EA)	0.21	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	17q21.33	17	49363104	ZNF652, PHB	ZNF652 - PHB	ENSG00000198740	ENSG00000167085	NA	631	40948	rs16948048-A	rs16948048	0	16948048	intron_variant	TRUE	NA	4e-13	12.397940008672037	NA	0.266	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	17q21.33	17	49363104	ZNF652, PHB	ZNF652 - PHB	ENSG00000198740	ENSG00000167085	NA	631	40948	rs16948048-A	rs16948048	0	16948048	intron_variant	TRUE	NA	1e-9	9	(EA)	0.242	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q21.21	4	80263187	PRDM8, FGF5	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675	NA	58858	3452	rs16998073-A	rs16998073	0	16998073	intergenic_variant	TRUE	NA	9e-24	23.045757490560675	NA	0.392	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	10q11.21	10	45458319	NR	MARCHF8, MARCHF8	NA	NA	ENSG00000165406, ENSG00000278545	NA	NA	rs7908745-G	rs7908745	0	7908745	missense_variant	FALSE	0.3143	9e-45	44.045757490560675	NA	0.05407684	[0.047-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3143	NA	0.05407684
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	10q11.21	10	45461800	NR	MARCHF8, MARCHF8	NA	NA	ENSG00000165406, ENSG00000278545	NA	NA	rs11394256-CA	rs11394256	0	11394256	non_coding_transcript_exon_variant	FALSE	0.2397	1e-17	17	NA	0.03578042	[0.028-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2397	NA	0.03578042
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	10q21.3	10	63214396	JMJD1C	JMJD1C	NA	NA	ENSG00000171988	NA	NA	rs41274072-C	rs41274072	0	41274072	missense_variant	FALSE	0.0317	1e-9	9	NA	0.06188018	[0.042-0.082] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0317	NA	0.06188018
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	10q22.1	10	69334748	HK1	HK1	NA	NA	ENSG00000156515	NA	NA	rs17476364-C	rs17476364	0	17476364	intron_variant	FALSE	0.1104	3e-69	68.52287874528034	NA	0.1009026	[0.09-0.112] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1104	NA	0.1009026
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	10q22.3	10	79354304	PPIF	PPIF	NA	NA	ENSG00000108179	NA	NA	rs7332-A	rs7332	0	7332	3_prime_UTR_variant	FALSE	0.4629	4e-11	10.397940008672037	NA	0.0237027	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4629	NA	0.0237027
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	10q24.33	10	103107201	NT5C2	NT5C2	NA	NA	ENSG00000076685	NA	NA	rs7896547-G	rs7896547	0	7896547	intron_variant	FALSE	0.3905	1e-40	40	NA	0.04894108	[0.042-0.056] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3905	NA	0.04894108
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	11p15.4	11	8825494	ST5	DENND2B	NA	NA	ENSG00000166444	NA	NA	rs10769966-A	rs10769966	0	10769966	intron_variant	FALSE	0.4939	3e-12	11.522878745280337	NA	0.0251476	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4939	NA	0.0251476
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	11p15.2	11	16737518	SOX6, C11orf58	SOX6, C11orf58	NA	NA	ENSG00000110693, ENSG00000110696	NA	NA	rs376898975-TA	rs376898975	1	60393896	intron_variant	FALSE	0.4053	2e-12	11.698970004336019	NA	0.02604947	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4053	NA	0.02604947
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	CD82	NA	NA	NA	NA	NA	NA	chr11:44581593-C	chr11:44581593	0	NA	NA	TRUE	0.3934	3e-10	9.522878745280337	NA	0.023341	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3934	NA	0.023341
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	11q13.1	11	64207494	FERMT3	FERMT3	NA	NA	ENSG00000149781	NA	NA	rs149000560-A	rs149000560	0	149000560	missense_variant	FALSE	0.0082	1e-16	16	NA	0.167884	[0.13-0.21] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0082	NA	0.167884
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	11q13.1	11	64256584	PLCB3	PLCB3	NA	NA	ENSG00000149782	NA	NA	rs588177-A	rs588177	0	588177	intron_variant	FALSE	0.6878	2e-10	9.698970004336019	NA	0.0247408	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.6878	NA	0.0247408
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	11q13.1	11	65706327	intergenic	RN7SL309P - KAT5	ENSG00000239356	ENSG00000172977	NA	10490	5669	rs10750766-A	rs10750766	0	10750766	regulatory_region_variant	TRUE	0.7085	5e-15	14.301029995663981	NA	0.03097515	[0.023-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.7085	NA	0.03097515
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	11q21	11	95575690	intergenic	SESN3 - FAM76B	ENSG00000149212	ENSG00000077458	NA	343149	193263	rs11021221-A	rs11021221	0	11021221	intron_variant	TRUE	0.1691	5e-17	16.30102999566398	NA	0.04021283	[0.031-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1691	NA	0.04021283
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	11q22.1	11	100767524	ARHGAP42	ARHGAP42	NA	NA	ENSG00000165895	NA	NA	rs667575-A	rs667575	0	667575	intron_variant	FALSE	0.7276	1e-15	15	NA	0.03247966	[0.025-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.7276	NA	0.03247966
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	11q23.3	11	116778201	ZNF259	ZPR1	NA	NA	ENSG00000109917	NA	NA	rs964184-C	rs964184	0	964184	3_prime_UTR_variant	FALSE	0.8665	8e-12	11.096910013008056	NA	0.03599952	[0.026-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.8665	NA	0.03599952
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	11q23.3	11	119260224	CBL	CBL	NA	NA	ENSG00000110395	NA	NA	rs68034047-C	rs68034047	0	68034047	intron_variant	FALSE	0.2235	2e-11	10.698970004336019	NA	0.02908862	[0.021-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2235	NA	0.02908862
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	12p13.31	12	8698522	RIMKLB	RIMKLB	NA	NA	ENSG00000166532	NA	NA	rs78241246-T	rs78241246	0	78241246	intron_variant	FALSE	0.2778	4e-15	14.397940008672037	NA	0.03149286	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2778	NA	0.03149286
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	12q13.3	12	56644387	ATP5B	ATP5F1B	NA	NA	ENSG00000110955	NA	NA	rs10716881-G	rs10716881	0	10716881	intron_variant	FALSE	0.3514	7e-9	8.154901959985743	NA	0.02172399	[0.014-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3514	NA	0.02172399
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	12q22	12	95464207	RP11-490G8.1	RNU6-735P - METAP2	ENSG00000222544	ENSG00000111142	NA	25364	9313	rs72449396-T	rs72449396	0	72449396	regulatory_region_variant	TRUE	0.3368	2e-20	19.69897000433602	NA	0.03519339	[0.028-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3368	NA	0.03519339
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	12q24.12	12	111466567	ATXN2	ATXN2	NA	NA	ENSG00000204842	NA	NA	rs4766578-A	rs4766578	0	4766578	intron_variant	FALSE	0.5029	3e-75	74.52287874528034	NA	0.06562279	[0.059-0.073] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.5029	NA	0.06562279
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	12q24.13	12	112541231	intergenic	PTPN11 - RPH3A	ENSG00000179295	ENSG00000089169	NA	31313	29149	rs35675096-A	rs35675096	0	35675096	intergenic_variant	TRUE	0.0895	5e-48	47.30102999566398	NA	0.09310965	[0.081-0.106] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0895	NA	0.09310965
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	12q24.31	12	120482327	DYNLL1	DYNLL1	NA	NA	ENSG00000088986	NA	NA	rs11352199-A	rs11352199	0	11352199	intron_variant	FALSE	0.4465	5e-78	77.30102999566398	NA	0.06803904	[0.061-0.075] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4465	NA	0.06803904
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	12q24.31	12	120582447	POP5	POP5 - RPL11P5	ENSG00000167272	ENSG00000242137	NA	1045	11568	rs523522-T	rs523522	0	523522	regulatory_region_variant	TRUE	0.3319	2e-83	82.69897000433602	NA	0.07367767	[0.066-0.081] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3319	NA	0.07367767
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	13q14.12	13	45014070	RP11-321C24.1, GPALPP1	GPALPP1	NA	NA	ENSG00000133114	NA	NA	rs73181516-G	rs73181516	0	73181516	intron_variant	FALSE	0.0749	3e-10	9.522878745280337	NA	0.04308981	[0.03-0.057] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0749	NA	0.04308981
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	13q14.3	13	50814824	DLEU7-AS1, DLEU7	DLEU7, DLEU1	NA	NA	ENSG00000186047, ENSG00000176124	NA	NA	rs9535495-T	rs9535495	0	9535495	intron_variant	FALSE	0.5569	1e-12	12	NA	0.02588124	[0.019-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.5569	NA	0.02588124
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	7q11.23	7	73627755	MLXIPL	MLXIPL - VPS37D	ENSG00000009950	ENSG00000176428	NA	3212	40076	rs62466318-T	rs62466318	0	62466318	intergenic_variant	TRUE	0.2039	8e-16	15.096910013008056	NA	0.03591725	[0.027-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2039	NA	0.03591725
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	7q31.2	7	116560038	CAV1	CAV1	NA	NA	ENSG00000105974	NA	NA	rs9920-C	rs9920	0	9920	3_prime_UTR_variant	FALSE	0.1051	1e-19	19	NA	0.05312012	[0.042-0.065] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1051	NA	0.05312012
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	7q33	7	134698032	intergenic	BPGM - TUBB3P2	ENSG00000172331	ENSG00000230101	NA	18216	36866	rs4524734-T	rs4524734	0	4524734	intergenic_variant	TRUE	0.3499	8e-33	32.096910013008056	NA	0.04474542	[0.037-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3499	NA	0.04474542
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	7q34	7	142954267	KEL	KEL, KEL	NA	NA	ENSG00000276615, ENSG00000197993	NA	NA	rs8176059-A	rs8176059	0	8176059	missense_variant	FALSE	0.0113	4e-9	8.397940008672037	NA	0.09995991	[0.067-0.133] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0113	NA	0.09995991
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	8p23.1	8	9169430	RP11-10A14.4	PPP1R3B - RPL10AP3	ENSG00000173281	ENSG00000215264	NA	17856	25153562	rs365309-G	rs365309	0	365309	intron_variant	TRUE	0.3125	3e-18	17.522878745280337	NA	0.03414643	[0.026-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3125	NA	0.03414643
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	8p21.2	8	26409318	BNIP3L	BNIP3L	NA	NA	ENSG00000104765	NA	NA	rs3808576-A	rs3808576	0	3808576	intron_variant	FALSE	0.7007	1e-12	12	NA	0.02822422	[0.02-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.7007	NA	0.02822422
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	8p11.21	8	41655063	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs6150565-C	rs6150565	0	6150565	3_prime_UTR_variant	FALSE	0.5335	1e-12	12	NA	0.0256901	[0.019-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.5335	NA	0.0256901
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	8p11.21	8	41691973	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs72638986-A	rs72638986	0	72638986	intron_variant	FALSE	0.0338	2e-19	18.69897000433602	NA	0.08931233	[0.07-0.109] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0338	NA	0.08931233
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	8p11.21	8	41732218	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs149489081-G	rs149489081	0	149489081	intron_variant	FALSE	0.0117	2e-10	9.698970004336019	NA	0.1126133	[0.078-0.147] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0117	NA	0.1126133
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	8p11.21	8	41772929	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs4737010-A	rs4737010	0	4737010	intron_variant	FALSE	0.2282	8e-30	29.096910013008056	NA	0.04870744	[0.04-0.057] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2282	NA	0.04870744
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	8q13.3	8	71601857	intergenic	EYA1 - NA	ENSG00000104313	NA	NA	9832	NA	rs12547135-C	rs12547135	0	12547135	intergenic_variant	TRUE	0.2434	8e-9	8.096910013008056	NA	0.02417935	[0.016-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2434	NA	0.02417935
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	8q21.2	8	85361801	CA1	CA1	NA	NA	ENSG00000133742	NA	NA	rs6997458-G	rs6997458	0	6997458	intron_variant	FALSE	0.5709	5e-11	10.301029995663981	NA	0.02372143	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.5709	NA	0.02372143
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	8q23.3	8	115655407	TRPS1	TRPS1	NA	NA	ENSG00000104447	NA	NA	rs2737265-G	rs2737265	0	2737265	intron_variant	FALSE	0.2824	1e-21	21	NA	0.03816234	[0.03-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2824	NA	0.03816234
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	8q24.3	8	141218810	SLC45A4	SLC45A4	NA	NA	ENSG00000022567	NA	NA	rs753778-A	rs753778	0	753778	missense_variant	FALSE	0.2935	5e-10	9.301029995663981	NA	0.02442285	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2935	NA	0.02442285
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	9p24.1	9	4855858	RCL1	RCL1	NA	NA	ENSG00000120158	NA	NA	rs7853365-C	rs7853365	0	7853365	intron_variant	FALSE	0.2073	5e-10	9.301029995663981	NA	0.02752521	[0.019-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2073	NA	0.02752521
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	9p22.2	9	16901230	intergenic	BNC2 - NA	ENSG00000173068	NA	NA	30387	NA	rs13300853-T	rs13300853	0	13300853	intergenic_variant	TRUE	0.3464	6e-10	9.221848749616356	NA	0.02334518	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3464	NA	0.02334518
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	9p13.3	9	34057211	intergenic	RN7SKP114 - DCAF12	ENSG00000222259	ENSG00000198876	NA	6967	29176	rs34756862-T	rs34756862	0	34756862	intergenic_variant	TRUE	0.3611	5e-13	12.301029995663981	NA	0.02771473	[0.02-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3611	NA	0.02771473
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	9q21.13	9	74364687	intergenic	NA	NA	NA	NA	NA	NA	rs140297755-CCAA	rs140297755	0	140297755	intergenic_variant	TRUE	0.3269	6e-10	9.221848749616356	NA	0.02410071	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3269	NA	0.02410071
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	9q22.1	9	88783043	intergenic	MIR4289 - NA	ENSG00000265873	NA	NA	37138	NA	rs73652622-G	rs73652622	0	73652622	intron_variant	TRUE	0.0641	3e-11	10.522878745280337	NA	0.04914156	[0.035-0.064] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0641	NA	0.04914156
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	9q22.2	9	89388764	SEMA4D	SEMA4D	NA	NA	ENSG00000187764	NA	NA	rs11526468-T	rs11526468	0	11526468	missense_variant	FALSE	0.298	7e-10	9.154901959985743	NA	0.02416072	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.298	NA	0.02416072
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	9q34.13	9	132986603	GFI1B	GFI1B	NA	NA	ENSG00000165702	NA	NA	rs61469632-C	rs61469632	0	61469632	intron_variant	FALSE	0.0622	9e-21	20.045757490560675	NA	0.06988945	[0.055-0.085] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0622	NA	0.06988945
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	9q34.2	9	134085798	intergenic	ARF4P1 - WDR5-DT	ENSG00000271525	ENSG00000273249	NA	6354	46444	rs35259020-T	rs35259020	0	35259020	intergenic_variant	TRUE	0.1638	1e-10	10	NA	0.03132414	[0.022-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1638	NA	0.03132414
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	9q34.2	9	134226324	intergenic	RNU6ATAC - LINC02247	ENSG00000221676	ENSG00000223729	NA	61760	67607	rs1475718-A	rs1475718	0	1475718	TF_binding_site_variant	TRUE	0.4444	7e-18	17.154901959985743	NA	0.03149688	[0.024-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4444	NA	0.03149688
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	9q34.3	9	137205865	NDOR1	NDOR1	NA	NA	ENSG00000188566	NA	NA	rs113809617-G	rs113809617	0	113809617	missense_variant	FALSE	0.1335	3e-14	13.522878745280337	NA	0.04119558	[0.031-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1335	NA	0.04119558
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	10p12.1	10	24929314	PRTFDC1	PRTFDC1	NA	NA	ENSG00000099256	NA	NA	rs10828725-T	rs10828725	0	10828725	intron_variant	FALSE	0.3704	1e-205	205	NA	0.1134682	[0.11-0.12] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3704	NA	0.1134682
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	NEK4	NA	NA	NA	NA	NA	NA	rs7620039-A	chr5:52095943_G_A	0	NA	NA	TRUE	0.3796	4e-13	12.397940008672037	NA	0.02687742	[0.02-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3796	NA	0.02687742
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	FLNB	NA	NA	NA	NA	NA	NA	rs732527-C	chr5:75996909_G_A	0	NA	NA	TRUE	0.3585	4e-18	17.397940008672037	NA	0.0327628	[0.025-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3585	NA	0.0327628
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	LINC00877	NA	NA	NA	NA	NA	NA	rs4282028-C	chr7:6086610_C_G	0	NA	NA	TRUE	0.6961	2e-13	12.698970004336019	NA	0.02888229	[0.021-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.6961	NA	0.02888229
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	PLS1	NA	NA	NA	NA	NA	NA	rs1357529-G	chr7:32908135_C_G	0	NA	NA	TRUE	0.5911	2e-11	10.698970004336019	NA	0.02438128	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.5911	NA	0.02438128
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	TFRC	NA	NA	NA	NA	NA	NA	rs113635136-CA	chr11:44581593_T_C	0	NA	NA	TRUE	0.2392	3e-9	8.522878745280337	NA	0.02531664	[0.017-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2392	NA	0.02531664
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	FGFRL1	NA	NA	NA	NA	NA	NA	rs77822621-T	chr14:65281472_G_C	0	NA	NA	TRUE	0.0424	6e-10	9.221848749616356	NA	0.05464981	[0.037-0.072] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0424	NA	0.05464981
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	intergenic	NA	NA	NA	NA	NA	NA	rs218265-C	chr14:103044709_G_GA	0	NA	NA	TRUE	0.1572	2e-16	15.698970004336019	NA	0.04118096	[0.031-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1572	NA	0.04118096
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	RP11-673E1.4	NA	NA	NA	NA	NA	NA	rs13101482-A	chr19:10739143_A_C	0	NA	NA	TRUE	0.6882	1e-57	57	NA	0.0622885	[0.055-0.07] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.6882	NA	0.0622885
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6p21.1	6	41984773	CCND3	CCND3	NA	NA	ENSG00000112576	NA	NA	rs113267280-G	rs113267280	0	113267280	intron_variant	FALSE	0.0102	4e-10	9.397940008672037	NA	0.1197863	[0.082-0.157] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0102	NA	0.1197863
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6p21.1	6	43792590	intergenic	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	6103	52288	rs11967262-G	rs11967262	0	11967262	regulatory_region_variant	TRUE	0.4889	5e-13	12.301029995663981	NA	0.0259432	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4889	NA	0.0259432
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6p12.3	6	47484534	CD2AP	CD2AP	NA	NA	ENSG00000198087	NA	NA	rs9296559-C	rs9296559	0	9296559	intron_variant	FALSE	0.2753	7e-18	17.154901959985743	NA	0.03449695	[0.027-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2753	NA	0.03449695
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6q21	6	108639637	FOXO3	FOXO3	NA	NA	ENSG00000118689	NA	NA	rs9486913-G	rs9486913	0	9486913	intron_variant	FALSE	0.1564	3e-10	9.522878745280337	NA	0.03106927	[0.021-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1564	NA	0.03106927
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6q21	6	109265453	C6orf183	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs932223-C	rs932223	0	932223	intron_variant	FALSE	0.478	3e-10	9.522878745280337	NA	0.02257755	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.478	NA	0.02257755
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6q21	6	110438805	SLC22A16	SLC22A16	NA	NA	ENSG00000004809	NA	NA	rs12210538-G	rs12210538	0	12210538	missense_variant	FALSE	0.2371	1e-14	14	NA	0.03252877	[0.024-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2371	NA	0.03252877
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6q22.32	6	125857965	NCOA7	NCOA7	NA	NA	ENSG00000111912	NA	NA	rs6920965-A	rs6920965	0	6920965	intron_variant	FALSE	0.397	7e-9	8.154901959985743	NA	0.02120631	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.397	NA	0.02120631
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6q22.33	6	127098689	intergenic	NA - RSPO3	NA	ENSG00000146374	NA	NA	19982	rs2745349-C	rs2745349	0	2745349	intron_variant	TRUE	0.2932	1e-9	9	NA	0.02410666	[0.016-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2932	NA	0.02410666
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6q23.2	6	132499141	STX7	STX7	NA	NA	ENSG00000079950	NA	NA	rs147324647-CCT	rs147324647	0	147324647	intron_variant	FALSE	0.455	7e-10	9.154901959985743	NA	0.02235024	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.455	NA	0.02235024
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6q23.3	6	135001482	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs9402673-T	rs9402673	0	9402673	intron_variant	FALSE	0.429	7e-20	19.154901959985743	NA	0.03313665	[0.026-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.429	NA	0.03313665
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6q24.1	6	139514643	intergenic	LINC01625 - ATP5PBP6	ENSG00000238099	ENSG00000219806	NA	39985	99795	rs668887-A	rs668887	0	668887	intron_variant	TRUE	0.9629	1e-176	176	NA	0.2733505	[0.25-0.29] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.9629	NA	0.2733505
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	6q24.1	6	139519556	intergenic	LINC01625 - ATP5PBP6	ENSG00000238099	ENSG00000219806	NA	44898	94882	rs592423-C	rs592423	0	592423	intron_variant	TRUE	0.5539	1e-253	253	NA	0.1225825	[0.12-0.13] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.5539	NA	0.1225825
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	EIF2AK1	NA	NA	NA	NA	NA	NA	chr7:6086610-G	chr7:6086610	0	NA	NA	TRUE	0.0435	4e-19	18.397940008672037	NA	0.07837167	[0.061-0.096] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0435	NA	0.07837167
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	7p21.1	7	16660352	BZW2	BZW2	NA	NA	ENSG00000136261	NA	NA	rs706027-T	rs706027	0	706027	intron_variant	FALSE	0.3809	5e-26	25.30102999566398	NA	0.03911746	[0.032-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3809	NA	0.03911746
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	7p21.1	7	16691417	BZW2	BZW2	NA	NA	ENSG00000136261	NA	NA	rs696281-T	rs696281	0	696281	intron_variant	FALSE	0.2149	2e-27	26.69897000433602	NA	0.04782177	[0.039-0.056] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2149	NA	0.04782177
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	KBTBD2	NA	NA	NA	NA	NA	NA	chr7:32908135-G	chr7:32908135	0	NA	NA	TRUE	0.3746	6e-9	8.221848749616356	NA	0.02145397	[0.014-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3746	NA	0.02145397
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	7p12.3	7	47417868	TNS3	TNS3	NA	NA	ENSG00000136205	NA	NA	rs865603-A	rs865603	0	865603	intron_variant	FALSE	0.9608	4e-9	8.397940008672037	NA	0.05464258	[0.037-0.073] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.9608	NA	0.05464258
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	8p22	8	13073995	Intergenic	RNU6-842P - DLC1	ENSG00000284861	ENSG00000164741	NA	29539	9366	rs144222594-A	rs144222594	0	144222594	intergenic_variant	TRUE	0.998	2e-6	5.698970004336019	(AA)	0.234	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.998	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q13.31	3	115616672	Intergenic	NA - GAP43	NA	ENSG00000172020	NA	NA	6838	rs78274021-T	rs78274021	0	78274021	intergenic_variant	TRUE	0.998	2e-6	5.698970004336019	(AA)	0.27	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.998	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	5q14.1	5	78749087	Intergenic	LHFPL2	NA	NA	ENSG00000145685	NA	NA	rs185237819-G	rs185237819	0	185237819	intron_variant	FALSE	1.0	2e-6	5.698970004336019	(AA)	0.631	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	7p15.2	7	26530916	Intergenic	NA - KIAA0087	NA	ENSG00000122548	NA	NA	2205	rs12700745-G	rs12700745	0	12700745	intergenic_variant	TRUE	0.805	2e-6	5.698970004336019	(AA)	0.019	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.805	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	2q24.1	2	158872545	Intergenic	OR7E28P - OR7E90P	ENSG00000251491	ENSG00000188668	NA	9260	2097	rs148169454-A	rs148169454	0	148169454	intergenic_variant	TRUE	0.989	2e-6	5.698970004336019	(AA)	0.087	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.989	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144542381	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	29857	rs6817238-T	rs6817238	0	6817238	intron_variant	TRUE	0.687	3e-13	12.522878745280337	NA	0.076	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.687	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78523715	AGPHD1	HYKK	NA	NA	ENSG00000188266	NA	NA	rs8031948-T	rs8031948	0	8031948	intron_variant	FALSE	0.336	3e-15	14.522878745280337	NA	0.075	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.336	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78557437	Intergenic	PSMA4 - CHRNA5	ENSG00000041357	ENSG00000169684	NA	5020	8083	rs72740955-T	rs72740955	0	72740955	intergenic_variant	TRUE	0.338	1e-14	14	NA	0.075	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.338	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78427490	Intergenic	CRABP1 - IREB2	ENSG00000166426	ENSG00000136381	NA	79265	9941	rs72738704-C	rs72738704	0	72738704	regulatory_region_variant	TRUE	0.34	2e-13	12.698970004336019	NA	0.075	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.34	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	127996353	Intergenic	MGLL	NA	NA	ENSG00000074416	NA	NA	rs17282209-T	rs17282209	0	17282209	intron_variant	FALSE	0.883	1e-6	6	NA	0.075	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.883	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144567946	Intergenic	THEGL - KRT18P51	ENSG00000249693	ENSG00000250504	NA	87964439	4292	rs13140176-A	rs13140176	0	13140176	intron_variant	TRUE	0.65	1e-13	13	NA	0.074	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.65	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78438807	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs17405217-T	rs17405217	0	17405217	non_coding_transcript_exon_variant	FALSE	0.336	2e-13	12.698970004336019	NA	0.074	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.336	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78437971	Intergenic	IREB2	NA	NA	ENSG00000136381	NA	NA	rs17483548-A	rs17483548	0	17483548	intron_variant	FALSE	0.336	3e-13	12.522878745280337	NA	0.074	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.336	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78490935	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs11858836-A	rs11858836	0	11858836	intron_variant	FALSE	0.336	3e-13	12.522878745280337	NA	0.074	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.336	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78630296	CHRNB4	CHRNB4	NA	NA	ENSG00000117971	NA	NA	rs2869548-A	rs2869548	0	2869548	intron_variant	FALSE	0.367	4e-13	12.397940008672037	NA	0.074	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.367	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q22.2	11	102855411	Intergenic	MMP3 - MMP12	ENSG00000149968	ENSG00000262406	NA	11802	7325	rs737693-A	rs737693	0	737693	intergenic_variant	TRUE	0.885	9e-7	6.045757490560675	NA	0.073	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.885	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q22.2	11	102858254	Intergenic	MMP3 - MMP12	ENSG00000149968	ENSG00000262406	NA	14645	4482	rs72983513-T	rs72983513	0	72983513	intergenic_variant	TRUE	0.886	9e-7	6.045757490560675	NA	0.073	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.886	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q22.2	11	102866461	MMP12	MMP12	NA	NA	ENSG00000262406	NA	NA	rs28381684-A	rs28381684	0	28381684	intron_variant	FALSE	0.886	1e-6	6	NA	0.073	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.886	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	89150413	Intergenic	RNU6-907P - GPRIN3	ENSG00000212226	ENSG00000185477	NA	19460	85970	rs140237746-A	rs140237746	0	140237746	intergenic_variant	TRUE	0.145	5e-6	5.301029995663981	NA	0.073	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.145	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	1p13.3	1	108058660	Intergenic	LINC02785	NA	NA	ENSG00000226822	NA	NA	rs12121801-T	rs12121801	0	12121801	intron_variant	FALSE	0.905	5e-6	5.301029995663981	NA	0.073	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.905	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q27	4	122584901	Intergenic	NA - IL21	NA	ENSG00000138684	NA	NA	25207	rs1512973-G	rs1512973	0	1512973	regulatory_region_variant	TRUE	0.4	5e-6	5.301029995663981	(AA)	0.073	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.4	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144585304	Intergenic	KRT18P51 - HHIP-AS1	ENSG00000250504	ENSG00000248890	NA	12321	57618	rs13141641-T	rs13141641	0	13141641	intron_variant	TRUE	0.63	4e-14	13.397940008672037	NA	0.072	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.63	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144513749	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	58489	rs1512281-A	rs1512281	0	1512281	intron_variant	TRUE	0.628	6e-14	13.221848749616356	NA	0.072	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.628	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78535744	AGPHD1	HYKK	NA	NA	ENSG00000188266	NA	NA	rs72738786-T	rs72738786	0	72738786	3_prime_UTR_variant	FALSE	0.336	8e-14	13.096910013008056	NA	0.072	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.336	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78778753	ADAMTS7	ADAMTS7	NA	NA	ENSG00000136378	NA	NA	rs12913260-A	rs12913260	0	12913260	intron_variant	FALSE	0.374	7e-8	7.154901959985743	NA	0.072	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.374	NA	NA
2017-03-16	27670397	Reyes-Gibby CC	2016-09-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27670397	Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients.	Pre-treatment pain in head and neck squamous cell carcinoma	148 European ancestry cases, 810 European ancestry controls	58 European ancestry cases, 352 European ancestry controls	17q25.3	17	77598082	NR	SEPTIN9 - NA	ENSG00000184640	NA	NA	97486	NA	rs1972597-G	rs1972597	0	1972597	intron_variant	TRUE	0.36	1e-7	7	NA	1.61	[1.35-1.93]	Illumina [714494]	N	pain	http://www.ebi.ac.uk/efo/EFO_0003843	GCST003760	Genome-wide genotyping array	0.36	1.61	NA
2017-03-16	27670397	Reyes-Gibby CC	2016-09-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27670397	Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients.	Pre-treatment pain in head and neck squamous cell carcinoma	148 European ancestry cases, 810 European ancestry controls	58 European ancestry cases, 352 European ancestry controls	1q44	1	247702471	RP11-634B7.4	OR13G1 - OR6F1	ENSG00000197437	ENSG00000169214	NA	22732	8965	rs3862188-G	rs3862188	0	3862188	intron_variant	TRUE	0.28	3e-8	7.522878745280337	NA	1.87	[1.50-2.33]	Illumina [714494]	N	pain	http://www.ebi.ac.uk/efo/EFO_0003843	GCST003760	Genome-wide genotyping array	0.28	1.87	NA
2017-03-16	27670397	Reyes-Gibby CC	2016-09-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27670397	Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients.	Pre-treatment pain in head and neck squamous cell carcinoma	148 European ancestry cases, 810 European ancestry controls	58 European ancestry cases, 352 European ancestry controls	12q24.22	12	117072747	NR	TESC	NA	NA	ENSG00000088992	NA	NA	rs11068315-A	rs11068315	0	11068315	intron_variant	FALSE	0.8	2e-6	5.698970004336019	NA	2.06	[1.53-2.77]	Illumina [714494]	N	pain	http://www.ebi.ac.uk/efo/EFO_0003843	GCST003760	Genome-wide genotyping array	0.8	2.06	NA
2017-03-16	27670397	Reyes-Gibby CC	2016-09-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27670397	Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients.	Pre-treatment pain in head and neck squamous cell carcinoma	148 European ancestry cases, 810 European ancestry controls	58 European ancestry cases, 352 European ancestry controls	2p23.1	2	30666058	NR	LCLAT1 - CAPN13	ENSG00000172954	ENSG00000162949	NA	21833	56713	rs12464483-A	rs12464483	0	12464483	regulatory_region_variant	TRUE	0.15	2e-6	5.698970004336019	NA	1.7	[1.37-2.12]	Illumina [714494]	N	pain	http://www.ebi.ac.uk/efo/EFO_0003843	GCST003760	Genome-wide genotyping array	0.15	1.7	NA
2017-03-16	27670397	Reyes-Gibby CC	2016-09-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27670397	Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients.	Pre-treatment pain in head and neck squamous cell carcinoma	148 European ancestry cases, 810 European ancestry controls	58 European ancestry cases, 352 European ancestry controls	16q21	16	62453185	NR	NA	NA	NA	NA	NA	NA	rs1834077-A	rs1834077	0	1834077	intergenic_variant	TRUE	0.39	3e-6	5.522878745280337	NA	1.63	[1.33-2.01]	Illumina [714494]	N	pain	http://www.ebi.ac.uk/efo/EFO_0003843	GCST003760	Genome-wide genotyping array	0.39	1.63	NA
2017-03-16	27670397	Reyes-Gibby CC	2016-09-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27670397	Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients.	Pre-treatment pain in head and neck squamous cell carcinoma	148 European ancestry cases, 810 European ancestry controls	58 European ancestry cases, 352 European ancestry controls	2q11.2	2	102090719	NR	IL1R1	NA	NA	ENSG00000115594	NA	NA	rs10199359-G	rs10199359	0	10199359	intron_variant	FALSE	0.18	3e-6	5.522878745280337	NA	1.64	[1.33-2.02]	Illumina [714494]	N	pain	http://www.ebi.ac.uk/efo/EFO_0003843	GCST003760	Genome-wide genotyping array	0.18	1.64	NA
2017-03-16	27670397	Reyes-Gibby CC	2016-09-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27670397	Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients.	Pre-treatment pain in head and neck squamous cell carcinoma	148 European ancestry cases, 810 European ancestry controls	58 European ancestry cases, 352 European ancestry controls	6p12.2	6	52270696	NR	MCM3	NA	NA	ENSG00000112118	NA	NA	rs3789775-A	rs3789775	0	3789775	intron_variant	FALSE	0.13	3e-6	5.522878745280337	NA	1.8	[1.40-2.30]	Illumina [714494]	N	pain	http://www.ebi.ac.uk/efo/EFO_0003843	GCST003760	Genome-wide genotyping array	0.13	1.8	NA
2017-03-16	27670397	Reyes-Gibby CC	2016-09-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27670397	Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients.	Pre-treatment pain in head and neck squamous cell carcinoma	148 European ancestry cases, 810 European ancestry controls	58 European ancestry cases, 352 European ancestry controls	1q41	1	216684671	NR	ESRRG	NA	NA	ENSG00000196482	NA	NA	rs4085154-?	rs4085154	0	4085154	intron_variant	FALSE	0.55	4e-6	5.3979400086720375	NA	1.5873016	[1.3-1.92]	Illumina [714494]	N	pain	http://www.ebi.ac.uk/efo/EFO_0003843	GCST003760	Genome-wide genotyping array	0.55	1.5873016	NA
2017-03-16	27670397	Reyes-Gibby CC	2016-09-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27670397	Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients.	Pre-treatment pain in head and neck squamous cell carcinoma	148 European ancestry cases, 810 European ancestry controls	58 European ancestry cases, 352 European ancestry controls	9q33.2	9	120963648	NR	C5	NA	NA	ENSG00000106804	NA	NA	rs17612-?	rs17612	0	17612	missense_variant	FALSE	0.26	5e-6	5.301029995663981	NA	4.347826	[2.27-7.69]	Illumina [714494]	N	pain	http://www.ebi.ac.uk/efo/EFO_0003843	GCST003760	Genome-wide genotyping array	0.26	4.347826	NA
2017-03-24	27670767	Chang SW	2016-09-27	Pharmacogenomics J	www.ncbi.nlm.nih.gov/pubmed/27670767	Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes.	Diabetes in response to antihypertensive drug treatment (treatment strategy interaction)	138 European American hypertensive cases with diabetes, 414 European American hypertensive cases without diabetes	157 Hispanic hypertensive cases with diabetes, 314 Hispanic hypertensive cases without diabetes, 39 African American hypertensive cases with diabetes, 78 African American hypertensive cases without diabetes	2p21	2	43650017	PLEKHH2, THADA	PLEKHH2	NA	NA	ENSG00000152527	NA	NA	rs11124945-G	rs11124945	0	11124945	intron_variant	FALSE	0.19	5e-8	7.301029995663981	NA	7.61	[3.39-17.09] (European)	Illumina [NR] (imputed)	N	response to antihypertensive drug, diabetes mellitus, response to beta blocker, response to calcium channel blocker	http://www.ebi.ac.uk/efo/EFO_0005405, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0007766, http://www.ebi.ac.uk/efo/EFO_0007767	GCST003797	Genome-wide genotyping array	0.19	7.61	NA
2017-03-24	27670767	Chang SW	2016-09-27	Pharmacogenomics J	www.ncbi.nlm.nih.gov/pubmed/27670767	Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes.	Diabetes in response to antihypertensive drug treatment (treatment strategy interaction)	138 European American hypertensive cases with diabetes, 414 European American hypertensive cases without diabetes	157 Hispanic hypertensive cases with diabetes, 314 Hispanic hypertensive cases without diabetes, 39 African American hypertensive cases with diabetes, 78 African American hypertensive cases without diabetes	2p21	2	43636315	THADA, PLEKHH2	Y_RNA - PLEKHH2	ENSG00000199964	ENSG00000152527	NA	15331	945	rs113296370-C	rs113296370	0	113296370	intergenic_variant	TRUE	0.19	2e-7	6.698970004336019	(European)	8.83	[8.01-9.65]	Illumina [NR] (imputed)	N	response to antihypertensive drug, diabetes mellitus, response to beta blocker, response to calcium channel blocker	http://www.ebi.ac.uk/efo/EFO_0005405, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0007766, http://www.ebi.ac.uk/efo/EFO_0007767	GCST003797	Genome-wide genotyping array	0.19	8.83	NA
2017-03-24	27670767	Chang SW	2016-09-27	Pharmacogenomics J	www.ncbi.nlm.nih.gov/pubmed/27670767	Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes.	Diabetes in response to antihypertensive drug treatment (treatment strategy interaction)	138 European American hypertensive cases with diabetes, 414 European American hypertensive cases without diabetes	157 Hispanic hypertensive cases with diabetes, 314 Hispanic hypertensive cases without diabetes, 39 African American hypertensive cases with diabetes, 78 African American hypertensive cases without diabetes	4p14	4	38813881	TLR10, TLR6, TLR1	TLR1	NA	NA	ENSG00000174125	NA	NA	rs4833103-?	rs4833103	0	4833103	intron_variant	FALSE	0.50	1e-7	7	(European)	5.26	[4.63-5.89]	Illumina [NR] (imputed)	N	response to antihypertensive drug, diabetes mellitus, response to beta blocker, response to calcium channel blocker	http://www.ebi.ac.uk/efo/EFO_0005405, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0007766, http://www.ebi.ac.uk/efo/EFO_0007767	GCST003797	Genome-wide genotyping array	0.5	5.26	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	7p15.1	7	28237488	JAZF1-AS1	JAZF1-AS1	NA	NA	ENSG00000234336	NA	NA	rs2158799-G	rs2158799	0	2158799	intron_variant	FALSE	0.6082	3e-49	48.52287874528034	NA	0.05471958	[0.047-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.6082	NA	0.05471958
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	7p15.1	7	28684757	CREB5	CREB5	NA	NA	ENSG00000146592	NA	NA	rs56388170-T	rs56388170	0	56388170	intron_variant	FALSE	0.2958	8e-77	76.09691001300806	NA	0.07391877	[0.066-0.082] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.2958	NA	0.07391877
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	7p13	7	44969742	MYO1G	MYO1G	NA	NA	ENSG00000136286	NA	NA	rs3735485-G	rs3735485	0	3735485	missense_variant	FALSE	0.8456	3e-11	10.522878745280337	NA	0.03301724	[0.023-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.8456	NA	0.03301724
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	7p12.3	7	47408324	TNS3	TNS3	NA	NA	ENSG00000136205	NA	NA	rs834603-G	rs834603	0	834603	intron_variant	FALSE	0.4908	7e-9	8.154901959985743	NA	0.02077506	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4908	NA	0.02077506
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	7p12.2	7	50218107	intergenic	SPATA48 - IKZF1	ENSG00000164500	ENSG00000185811	NA	58851	85961	rs11769630-A	rs11769630	0	11769630	intron_variant	TRUE	0.0748	7e-9	8.154901959985743	NA	0.04017788	[0.027-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.0748	NA	0.04017788
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	7q21.2	7	92606850	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs8179-C	rs8179	0	8179	3_prime_UTR_variant	FALSE	0.7915	2e-19	18.69897000433602	NA	0.0398395	[0.031-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.7915	NA	0.0398395
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	7q21.2	7	92779056	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs445-T	rs445	0	445	intron_variant	FALSE	0.0971	4e-64	63.39794000867204	NA	0.1026473	[0.091-0.115] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.0971	NA	0.1026473
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8q24.3	8	141327691	RP11-10J21.6	SLC45A4 - LINC01300	ENSG00000022567	ENSG00000253595	NA	19386	12814	rs6986779-T	rs6986779	0	6986779	regulatory_region_variant	TRUE	0.3592	5e-15	14.301029995663981	NA	0.02933897	[0.022-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.3592	NA	0.02933897
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8p23.1	8	10848901	RP11-177H2.2	PINX1 - XKR6	ENSG00000258724	ENSG00000171044	NA	9054	47144	rs1991651-G	rs1991651	0	1991651	intergenic_variant	TRUE	0.6178	2e-12	11.698970004336019	NA	0.02610339	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.6178	NA	0.02610339
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8p21.3	8	23109256	TNFRSF10C	TNFRSF10C	NA	NA	ENSG00000173535	NA	NA	rs12550612-A	rs12550612	0	12550612	intron_variant	FALSE	0.8225	3e-12	11.522878745280337	NA	0.03282826	[0.024-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.8225	NA	0.03282826
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8p12	8	30423317	RBPMS	RBPMS	NA	NA	ENSG00000157110	NA	NA	rs2979489-A	rs2979489	0	2979489	intron_variant	FALSE	0.7425	4e-13	12.397940008672037	NA	0.02961417	[0.022-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.7425	NA	0.02961417
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8q12.1	8	55878685	LYN	TGS1 - LYN	ENSG00000137574	ENSG00000254087	NA	52240	1150	rs2271400-T	rs2271400	0	2271400	regulatory_region_variant	TRUE	0.6871	3e-10	9.522878745280337	NA	0.02448989	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.6871	NA	0.02448989
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8q12.2	8	60738272	CHD7	CHD7	NA	NA	ENSG00000171316	NA	NA	rs7846314-T	rs7846314	0	7846314	intron_variant	FALSE	0.1865	6e-39	38.221848749616356	NA	0.06020929	[0.051-0.069] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.1865	NA	0.06020929
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8q13.2	8	67900953	intergenic	NDUFS5P6 - PREX2	ENSG00000255531	ENSG00000046889	NA	51615	51093	rs12542907-G	rs12542907	0	12542907	intergenic_variant	TRUE	0.402	7e-12	11.154901959985743	NA	0.02510393	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.402	NA	0.02510393
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8q22.3	8	102840179	AZIN1	AZIN1	NA	NA	ENSG00000155096	NA	NA	rs2436845-A	rs2436845	0	2436845	intron_variant	FALSE	0.4343	1e-9	9	NA	0.02204727	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4343	NA	0.02204727
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8q24.13	8	125479491	RP11-136O12.2	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	41088	380230	rs2954031-T	rs2954031	0	2954031	intron_variant	TRUE	0.4452	1e-9	9	NA	0.0219224	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4452	NA	0.0219224
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8q24.21	8	129599504	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs397731840-CT	rs397731840	1	60379390	intron_variant	FALSE	0.5942	9e-27	26.045757490560675	NA	0.04130679	[0.034-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.5942	NA	0.04130679
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	8q24.21	8	129612570	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs1982094-T	rs1982094	0	1982094	intron_variant	FALSE	0.0424	3e-16	15.522878745280337	NA	0.07404138	[0.056-0.092] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.0424	NA	0.07404138
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	9p24.1	9	4763176	intergenic	AK3 - ECM1P1	ENSG00000147853	ENSG00000270639	NA	21133	5441	rs385893-C	rs385893	0	385893	regulatory_region_variant	TRUE	0.5221	4e-14	13.397940008672037	NA	0.027096	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.5221	NA	0.027096
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	9p24.3	9	305428	DOCK8	DOCK8	NA	NA	ENSG00000107099	NA	NA	rs1969949-G	rs1969949	0	1969949	intron_variant	FALSE	0.7214	2e-11	10.698970004336019	NA	0.02701586	[0.019-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.7214	NA	0.02701586
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	9q34.13	9	132989126	GFI1B	GFI1B	NA	NA	ENSG00000165702	NA	NA	rs150813342-T	rs150813342	0	150813342	synonymous_variant	FALSE	0.0085	5e-11	10.301029995663981	NA	0.1332752	[0.093-0.173] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.0085	NA	0.1332752
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	9q34.2	9	133279427	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	3403	58301	rs635634-T	rs635634	0	635634	intergenic_variant	TRUE	0.1824	1e-19	19	NA	0.04200489	[0.033-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.1824	NA	0.04200489
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	9q34.3	9	136427805	INPP5E, PMPCA	PMPCA - INPP5E	ENSG00000165688	ENSG00000148384	NA	4044	814	rs71191701-C	rs71191701	0	71191701	intergenic_variant	TRUE	0.2916	3e-17	16.522878745280337	NA	0.03314689	[0.025-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.2916	NA	0.03314689
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p36.23	1	8853597	intergenic	RERE - ENO1	ENSG00000142599	ENSG00000074800	NA	4676	7403	rs12752838-G	rs12752838	0	12752838	intergenic_variant	TRUE	0.5035	1e-11	11	NA	0.02429055	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5035	NA	0.02429055
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p35.3	1	27859995	intergenic	PPP1R8 - THEMIS2	ENSG00000117751	ENSG00000130775	NA	8319	12548	rs56232812-C	rs56232812	0	56232812	intergenic_variant	TRUE	0.1037	5e-9	8.301029995663981	NA	0.03478097	[0.023-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.1037	NA	0.03478097
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2q24.2	2	159712765	NR	MARCHF7	NA	NA	ENSG00000136536	NA	NA	rs10173538-T	rs10173538	0	10173538	intron_variant	FALSE	0.3737	8e-12	11.096910013008056	NA	0.02537987	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3737	NA	0.02537987
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2q24.3	2	168850753	NOSTRIN, SPC25	NOSTRIN, NOSTRIN, SPC25, SPC25	NA	NA	ENSG00000275326, ENSG00000163072, ENSG00000152253, ENSG00000277909	NA	NA	rs139707092-A	rs139707092	1	5836209	intron_variant	FALSE	0.3195	6e-15	14.221848749616356	NA	0.03011005	[0.023-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3195	NA	0.03011005
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2q31.3	2	181443625	intergenic	LINC01934 - ITGA4	ENSG00000234663	ENSG00000115232	NA	34304	13577	rs6740847-G	rs6740847	0	6740847	intergenic_variant	TRUE	0.5637	1e-12	12	NA	0.02584311	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5637	NA	0.02584311
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2q35	2	218135259	CXCR2	CXCR2	NA	NA	ENSG00000180871	NA	NA	rs55799208-A	rs55799208	0	55799208	missense_variant	FALSE	0.0029	8e-42	41.096910013008056	NA	0.4863582	[0.42-0.56] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0029	NA	0.4863582
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2q35	2	218156235	intergenic	CXCR2 - CXCR1	ENSG00000180871	ENSG00000163464	NA	18984	6606	rs114050631-T	rs114050631	0	114050631	regulatory_region_variant	TRUE	0.0106	2e-17	16.69897000433602	NA	0.1653164	[0.13-0.2] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0106	NA	0.1653164
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2q35	2	218297999	PNKD	PNKD	NA	NA	ENSG00000127838	NA	NA	rs145013566-CA	rs145013566	0	145013566	intron_variant	FALSE	0.5244	6e-11	10.221848749616356	NA	0.02426803	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5244	NA	0.02426803
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2q37.3	2	236867522	intergenic	NA	NA	NA	NA	NA	NA	rs9287604-C	rs9287604	0	9287604	intergenic_variant	TRUE	0.7326	2e-13	12.698970004336019	NA	0.03024851	[0.022-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.7326	NA	0.03024851
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	3p22.1	3	42854959	KRBOX1, ACKR2, RP11-141M3.5	ACKR2, KRBOX1	NA	NA	ENSG00000144648, ENSG00000240747	NA	NA	rs9872440-C	rs9872440	0	9872440	intron_variant	FALSE	0.3857	4e-12	11.397940008672037	NA	0.02552774	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3857	NA	0.02552774
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	3p21.31	3	47220756	KIF9-AS1	KIF9-AS1	NA	NA	ENSG00000227398	NA	NA	rs11920354-A	rs11920354	0	11920354	intron_variant	FALSE	0.3862	5e-9	8.301029995663981	NA	0.02145963	[0.014-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3862	NA	0.02145963
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	3q21.3	3	128582547	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	6461	37422	rs2734031-C	rs2734031	0	2734031	intergenic_variant	TRUE	0.9094	5e-23	22.30102999566398	NA	0.06230471	[0.05-0.075] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.9094	NA	0.06230471
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	3q21.3	3	128604581	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	28495	15388	rs6782228-C	rs6782228	0	6782228	intergenic_variant	TRUE	0.2678	3e-14	13.522878745280337	NA	0.03102483	[0.023-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.2678	NA	0.03102483
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	3q23	3	141208279	intergenic	SPSB4 - PXYLP1	ENSG00000175093	ENSG00000155893	NA	59668	20447	rs143699489-G	rs143699489	0	143699489	intergenic_variant	TRUE	0.1269	1e-11	11	NA	0.03690768	[0.026-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.1269	NA	0.03690768
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	3q23	3	141487958	RASA2	RASA2	NA	NA	ENSG00000155903	NA	NA	rs9819371-T	rs9819371	0	9819371	intron_variant	FALSE	0.065	1e-9	9	NA	0.0442047	[0.03-0.058] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.065	NA	0.0442047
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	4p16.3	4	711285	PCGF3	PCGF3	NA	NA	ENSG00000185619	NA	NA	rs11734460-T	rs11734460	0	11734460	intron_variant	FALSE	0.3122	7e-11	10.154901959985743	NA	0.02531494	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3122	NA	0.02531494
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	NA	NA	NA	TADA2B, RP11-367J11.2	NA	NA	NA	NA	NA	NA	rs11931598-T	rs11931598	0	11931598	intron_variant	TRUE	0.4444	1e-9	9	NA	0.02222182	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4444	NA	0.02222182
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	4q12	4	54542832	intergenic	LINC02283 - LINC02260	ENSG00000248184	ENSG00000250456	NA	186878	60379	rs218265-C	rs218265	0	218265	intergenic_variant	TRUE	0.1572	2e-16	15.698970004336019	NA	0.04109447	[0.031-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.1572	NA	0.04109447
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	4q12	4	54635120	intergenic	LINC02260 - KIT	ENSG00000250456	ENSG00000157404	NA	27989	22798	rs58548501-TA	rs58548501	0	58548501	intergenic_variant	TRUE	0.4858	2e-11	10.698970004336019	NA	0.02405265	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4858	NA	0.02405265
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	4q13.3	4	71752058	GC	GC	NA	NA	ENSG00000145321	NA	NA	rs1352846-G	rs1352846	0	1352846	intron_variant	FALSE	0.2919	1e-10	10	NA	0.02531522	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.2919	NA	0.02531522
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	4q13.3	4	73835795	CXCL6	CXCL8 - CXCL6	ENSG00000169429	ENSG00000124875	NA	92079	845	rs62312418-A	rs62312418	0	62312418	intergenic_variant	TRUE	0.4048	8e-45	44.096910013008056	NA	0.05179471	[0.045-0.059] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4048	NA	0.05179471
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	4q13.3	4	74094279	CXCL2	PPBPP2 - CXCL2	ENSG00000248848	ENSG00000081041	NA	38880	2761	rs11725704-G	rs11725704	0	11725704	regulatory_region_variant	TRUE	0.3762	1e-84	84	NA	0.07228309	[0.065-0.08] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3762	NA	0.07228309
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	4q21.22	4	82631138	SCD5	SCD5	NA	NA	ENSG00000145284	NA	NA	rs28476539-A	rs28476539	0	28476539	3_prime_UTR_variant	FALSE	0.1825	3e-10	9.522878745280337	NA	0.02932731	[0.02-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.1825	NA	0.02932731
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	4q24	4	105140377	AC004069.2	RNU6-351P - TET2	ENSG00000251906	ENSG00000168769	NA	165606	5498	rs7679673-A	rs7679673	0	7679673	intron_variant	TRUE	0.3746	1e-10	10	NA	0.02369403	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3746	NA	0.02369403
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	5p15.33	5	1104823	SLC12A7	SLC12A7, SLC12A7	NA	NA	ENSG00000113504, ENSG00000276482	NA	NA	rs35188965-T	rs35188965	0	35188965	intron_variant	FALSE	0.5795	1e-9	9	NA	0.02197885	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5795	NA	0.02197885
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	5p15.33	5	1285859	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs7705526-A	rs7705526	0	7705526	intron_variant	FALSE	0.329	1e-18	18	NA	0.03445749	[0.027-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.329	NA	0.03445749
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	5q13.2	5	69294573	CCDC125	CCDC125, CCDC125	NA	NA	ENSG00000277868, ENSG00000183323	NA	NA	rs11741826-C	rs11741826	0	11741826	intron_variant	FALSE	0.4442	2e-15	14.698970004336019	NA	0.02881436	[0.022-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4442	NA	0.02881436
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p34.3	1	36478315	CSF3R	CSF3R	NA	NA	ENSG00000119535	NA	NA	rs3917932-G	rs3917932	0	3917932	intron_variant	FALSE	0.5758	6e-38	37.221848749616356	NA	0.04685894	[0.04-0.054] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5758	NA	0.04685894
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p34.3	1	36482287	CSF3R	CSF3R	NA	NA	ENSG00000119535	NA	NA	rs3917914-A	rs3917914	0	3917914	intron_variant	FALSE	0.0115	2e-21	20.69897000433602	NA	0.1614943	[0.13-0.19] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0115	NA	0.1614943
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p34.1	1	45860202	MAST2	MAST2	NA	NA	ENSG00000086015	NA	NA	rs796415138-T	rs796415138	1	777498021	intron_variant	FALSE	0.4555	3e-10	9.522878745280337	NA	0.0231894	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4555	NA	0.0231894
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p32.2	1	56158423	RP1-158P9.1	NA - RPSAP20	NA	ENSG00000229871	NA	NA	49144	rs778387-G	rs778387	0	778387	intron_variant	TRUE	0.4042	4e-9	8.397940008672037	NA	0.0222433	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4042	NA	0.0222433
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p32.2	1	56440602	intergenic	LINC01767 - PLPP3	ENSG00000223956	ENSG00000162407	NA	23465	54159	rs7537229-A	rs7537229	0	7537229	intron_variant	TRUE	0.8958	1e-15	15	NA	0.04689552	[0.035-0.058] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.8958	NA	0.04689552
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p31.3	1	65445924	LEPR	LEPR	NA	NA	ENSG00000116678	NA	NA	rs9436747-C	rs9436747	0	9436747	intron_variant	FALSE	0.6284	1e-19	19	NA	0.03367764	[0.026-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.6284	NA	0.03367764
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p31.3	1	65640261	LEPR	LEPR	NA	NA	ENSG00000116678	NA	NA	rs1892534-T	rs1892534	0	1892534	3_prime_UTR_variant	FALSE	0.3767	4e-37	36.39794000867204	NA	0.04711612	[0.04-0.054] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3767	NA	0.04711612
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	NA	NA	NA	ELTD1	NA	NA	NA	NA	NA	NA	chr1:79411968-A	chr1:79411968	0	NA	NA	TRUE	0.0307	3e-11	10.522878745280337	NA	0.06903638	[0.049-0.089] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0307	NA	0.06903638
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p13.3	1	108200437	SLC25A24	SLC25A24	NA	NA	ENSG00000284468	NA	NA	rs663045-C	rs663045	0	663045	5_prime_UTR_variant	FALSE	0.5334	5e-11	10.301029995663981	NA	0.02368156	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5334	NA	0.02368156
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1p13.2	1	113834946	PTPN22	PTPN22	NA	NA	ENSG00000134242	NA	NA	rs2476601-G	rs2476601	0	2476601	missense_variant	FALSE	0.8983	5e-13	12.301029995663981	NA	0.04269255	[0.031-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.8983	NA	0.04269255
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1q23.2	1	159204893	DARC	CADM3-AS1, ACKR1	NA	NA	ENSG00000225670, ENSG00000213088	NA	NA	rs2814778-C	rs2814778	0	2814778	5_prime_UTR_variant	FALSE	0.0019	4e-12	11.397940008672037	NA	0.2915131	[0.21-0.37] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0019	NA	0.2915131
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1q23.2	1	159205095	CTA-134P22.2, DARC	ACKR1, CADM3-AS1	NA	NA	ENSG00000213088, ENSG00000225670	NA	NA	rs7550207-C	rs7550207	0	7550207	intron_variant	FALSE	0.2372	1e-10	10	NA	0.02711381	[0.019-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.2372	NA	0.02711381
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1q23.2	1	159205704	DARC	ACKR1, CADM3-AS1	NA	NA	ENSG00000213088, ENSG00000225670	NA	NA	rs34599082-T	rs34599082	0	34599082	missense_variant	FALSE	0.0138	9e-29	28.045757490560675	NA	0.1714806	[0.14-0.2] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0138	NA	0.1714806
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1q23.3	1	161639782	FCGR2B	FCGR3B - FCGR2B	ENSG00000162747	ENSG00000072694	NA	7819	23365	rs201950044-T	rs201950044	0	201950044	intergenic_variant	TRUE	0.1313	2e-11	10.698970004336019	NA	0.03666194	[0.026-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.1313	NA	0.03666194
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1q32.2	1	207860984	C1orf132	MIR29B2CHG	NA	NA	ENSG00000203709	NA	NA	rs4844622-T	rs4844622	0	4844622	intron_variant	FALSE	0.2412	6e-9	8.221848749616356	NA	0.02444337	[0.016-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.2412	NA	0.02444337
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1q42.13	1	226986191	ADCK3	COQ8A	NA	NA	ENSG00000163050	NA	NA	rs17592479-A	rs17592479	0	17592479	intron_variant	FALSE	0.5075	1e-12	12	NA	0.02538235	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5075	NA	0.02538235
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1q42.3	1	235926855	intergenic	RNU6-968P - LINC02768	ENSG00000206803	ENSG00000229291	NA	11334	31024	rs2208568-C	rs2208568	0	2208568	intergenic_variant	TRUE	0.8919	5e-26	25.30102999566398	NA	0.06150571	[0.05-0.073] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.8919	NA	0.06150571
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	1q44	1	247438293	NLRP3	NLRP3	NA	NA	ENSG00000162711	NA	NA	rs12239046-C	rs12239046	0	12239046	intron_variant	FALSE	0.6283	2e-18	17.69897000433602	NA	0.03240568	[0.025-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.6283	NA	0.03240568
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2p23.3	2	27508073	GCKR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs1260326-C	rs1260326	0	1260326	missense_variant	FALSE	0.6052	7e-18	17.154901959985743	NA	0.03150785	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.6052	NA	0.03150785
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2p21	2	43582208	THADA	THADA	NA	NA	ENSG00000115970	NA	NA	rs78487399-C	rs78487399	0	78487399	intron_variant	FALSE	0.0975	3e-11	10.522878745280337	NA	0.04032608	[0.028-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0975	NA	0.04032608
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2p16.1	2	54760823	EML6	EML6	NA	NA	ENSG00000214595	NA	NA	rs200476039-A	rs200476039	0	200476039	intron_variant	FALSE	0.0516	5e-10	9.301029995663981	NA	0.05302653	[0.036-0.07] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0516	NA	0.05302653
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2p15	2	61476184	RP11-355B11.2	XPO1, USP34-DT	NA	NA	ENSG00000082898, ENSG00000270820	NA	NA	rs10206089-A	rs10206089	0	10206089	non_coding_transcript_exon_variant	FALSE	0.3775	3e-9	8.522878745280337	NA	0.02368922	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3775	NA	0.02368922
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2p14	2	65438507	AC074391.1	SPRED2 - DNAJB12P1	ENSG00000198369	ENSG00000237979	NA	5870	62486	rs2860773-T	rs2860773	0	2860773	intron_variant	TRUE	0.4072	6e-9	8.221848749616356	NA	0.02121341	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4072	NA	0.02121341
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2q11.2	2	101160470	TBC1D8	TBC1D8	NA	NA	ENSG00000204634	NA	NA	rs7575217-G	rs7575217	0	7575217	intron_variant	FALSE	0.6725	3e-9	8.522878745280337	NA	0.02268867	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.6725	NA	0.02268867
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	2q14.1	2	113106194	IL1RN	RNU6-1180P - IL1RN	ENSG00000201805	ENSG00000136689	NA	19283	1020	rs2029582-C	rs2029582	0	2029582	regulatory_region_variant	TRUE	0.4811	2e-21	20.69897000433602	NA	0.03421705	[0.027-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4811	NA	0.03421705
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	13q34	13	110102320	Metazoa_SRP, COL4A1, RN7SKP10, COL4A2	RN7SL783P - COL4A1	ENSG00000265885	ENSG00000187498	NA	4169	46643	rs9521597-C	rs9521597	0	9521597	intron_variant	TRUE	NR	8e-6	5.096910013008056	(sleep duration, weekdays)	0.2616	[0.15-0.38] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	14q31.1	14	81344601	STON2, DYNLL1P1, GTF2A1, SEL1L	STON2	NA	NA	ENSG00000140022	NA	NA	rs2012796-A	rs2012796	0	2012796	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(sleep duration, weekdays)	0.2352	[0.14-0.34] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	18p11.32	18	2176439	RP11-161I6.2	NA	NA	NA	NA	NA	NA	rs1784848-C	rs1784848	0	1784848	intron_variant	TRUE	NR	9e-7	6.045757490560675	(sleep duration, weekdays)	0.5621	[0.34-0.79] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	18q22.1	18	67524254	RP11-638L3.1, DSEL	DSEL-AS1	NA	NA	ENSG00000265533	NA	NA	rs12606068-G	rs12606068	0	12606068	intron_variant	FALSE	NR	5e-6	5.301029995663981	(sleep duration, weekdays)	0.32	[0.18-0.46] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	chr3:20765319-TTGAGAGAA	chr3:20765319	0	NA	NA	TRUE	NR	5e-6	5.301029995663981	(sleep efficiency)	1.945	[1.11-2.78] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5p13.1	5	38767710	CTD-2127H9.1, RP11-122C5.2, OSMR, LIFR-AS1	OSMR-AS1	NA	NA	ENSG00000249740	NA	NA	rs10038470-G	rs10038470	0	10038470	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(sleep efficiency)	1.964	[1.13-2.8] unit increase	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q14.3	5	86216422	NBPF22P, PTP4A1P4	SCAMP1 - NBPF22P	ENSG00000085365	ENSG00000205449	NA	7735683	66038	rs2964898-T	rs2964898	0	2964898	intergenic_variant	TRUE	NR	9e-6	5.045757490560675	(sleep efficiency)	5.334	[2.98-7.69] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q35.2	5	174755929	CTD-2532K18.1, MIR4634, MSX2, HIGD1AP3	MIR4634 - NA	ENSG00000266890	NA	NA	4142	NA	rs28450080-T	rs28450080	0	28450080	intron_variant	TRUE	NR	5e-6	5.301029995663981	(sleep efficiency)	4.226	[2.41-6.04] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6p24.3	6	9851168	OFCC1	OFCC1	NA	NA	ENSG00000181355	NA	NA	rs111921861-C	rs111921861	0	111921861	intron_variant	FALSE	NR	2e-7	6.698970004336019	(sleep efficiency)	6.605	[4.14-9.07] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	7q33	7	136554034	PSMC1P3	ZP3P2 - NA	ENSG00000226066	NA	NA	65717	NA	rs74757156-T	rs74757156	0	74757156	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(sleep efficiency)	6.62	[3.88-9.36] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	8q21.13	8	83116293	NA	NA	NA	NA	NA	NA	NA	rs140707667-T	rs140707667	0	140707667	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(sleep efficiency)	6.589	[3.81-9.37] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	16q23.3	16	82609885	CDH13	NA - CDH13	NA	ENSG00000140945	NA	NA	17080	rs111702115-C	rs111702115	0	111702115	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(sleep efficiency)	2.553	[1.5-3.6] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	OR1M1, OR7G2, OR1M4P, OR7G1, OR7G3, ZNF317	NA	NA	NA	NA	NA	NA	chr19:9208706-TA	chr19:9208706	0	NA	NA	TRUE	NR	5e-6	5.301029995663981	(sleep efficiency)	1.95	[1.11-2.79] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	4q35.1	4	184250209	RP11-162O12.1, ENPP6, IRF2, STOX2	ENPP6 - RN7SL28P	ENSG00000164303	ENSG00000244512	NA	28979	28727	rs7695597-G	rs7695597	0	7695597	regulatory_region_variant	TRUE	NR	8e-6	5.096910013008056	(sleep efficiency, weekdays)	1.733	[0.97-2.5] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6q16.1	6	96200106	FUT9, UFL1-AS1, KRT18P50	FUT9, UFL1-AS1	NA	NA	ENSG00000172461, ENSG00000233797	NA	NA	rs142123475-A	rs142123475	0	142123475	non_coding_transcript_exon_variant	FALSE	NR	1e-6	6	(sleep efficiency, weekdays)	6.379	[3.82-8.94] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6q16.1	6	96341906	UFL1-AS1, FUT9, UFL1, FHL5	UFL1-AS1	NA	NA	ENSG00000233797	NA	NA	rs147738873-A	rs147738873	1	112431985	intron_variant	FALSE	NR	6e-8	7.221848749616356	(sleep efficiency, weekdays)	4.642	[2.97-6.32] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6q16.1	6	96445724	UFL1-AS1, UFL1, FHL5, RPS7P8	UFL1-AS1	NA	NA	ENSG00000233797	NA	NA	rs75842709-T	rs75842709	0	75842709	intron_variant	FALSE	NR	1e-8	8	(sleep efficiency, weekdays)	5.711	[3.74-7.68] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6q22.1	6	117222225	VGLL2, ROS1, GOPC, RNA5SP214	RNA5SP214 - VGLL2	ENSG00000200248	ENSG00000170162	NA	161426	43333	rs4946246-T	rs4946246	0	4946246	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(sleep efficiency, weekdays)	2.116	[1.25-2.99] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	7p12.3	7	45670500	ADCY1, SEPT7P2, IGFBP1, IGFBP3	ADCY1	NA	NA	ENSG00000164742	NA	NA	rs79209880-T	rs79209880	0	79209880	intron_variant	FALSE	NR	1e-7	7	(sleep efficiency, weekdays)	8.057	[5.09-11.02] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	12q23.3	12	106561766	RP11-144F15.1, RFX4, POLR3B, RIC8B	POLR3B - RFX4	ENSG00000013503	ENSG00000111783	NA	51568	21238	rs11610873-C	rs11610873	0	11610873	intron_variant	TRUE	NR	5e-6	5.301029995663981	(sleep efficiency, weekdays)	3.398	[1.94-4.86] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	14q32.2	14	97075293	LINC00618, VRK1	NA - LINC02304	NA	ENSG00000259110	NA	NA	79564	rs78807545-T	rs78807545	0	78807545	regulatory_region_variant	TRUE	NR	8e-6	5.096910013008056	(sleep efficiency, weekdays)	4.7	[2.64-6.76] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	15q26.1	15	92463510	ST8SIA2, C15orf32, ENO1P2, FAM174B	ST8SIA2	NA	NA	ENSG00000140557	NA	NA	rs4777989-A	rs4777989	0	4777989	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(sleep efficiency, weekdays)	1.84	[1.06-2.62] unit increase	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	16p13.12	16	13769475	U95743.1, ERCC4, RPS26P52	NA	NA	NA	NA	NA	NA	rs74321030-C	rs74321030	0	74321030	intron_variant	TRUE	NR	8e-6	5.096910013008056	(sleep efficiency, weekdays)	5.002	[2.8-7.2] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	18p11.21	18	15046606	FGF7P1, ANKRD30B, BNIP3P3, MIR3156-2	LINC01443 - NA	ENSG00000266554	NA	NA	72391	NA	rs71365296-A	rs71365296	1	4581792	intergenic_variant	TRUE	NR	9e-6	5.045757490560675	(sleep efficiency, weekdays)	2.011	[1.12-2.9] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1p13.3	1	107781261	VAV3, VAV3-AS1	VAV3	NA	NA	ENSG00000134215	NA	NA	rs17556028-T	rs17556028	0	17556028	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(sleep latency)	0.2356	[0.14-0.34] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	2p24.1	2	23315647	KLHL29	NA - KLHL29	NA	ENSG00000119771	NA	NA	69532	rs62126824-G	rs62126824	0	62126824	intergenic_variant	TRUE	NR	6e-6	5.221848749616356	(sleep latency)	0.4623	[0.26-0.66] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	4q27	4	122626441	IL21-AS1, IL21, CETN4P, BBS12	IL21-AS1	NA	NA	ENSG00000227145	NA	NA	rs62324204-C	rs62324204	0	62324204	non_coding_transcript_exon_variant	FALSE	NR	1e-6	6	(sleep latency)	0.4116	[0.25-0.58] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5p13.2	5	36406285	RNA5SP181, RANBP3L, NADKD1, NADKD1-AS1	NA - RNA5SP181	NA	ENSG00000222178	NA	NA	79058	rs114965806-T	rs114965806	0	114965806	intergenic_variant	TRUE	NR	1e-6	6	(sleep latency)	0.8268	[0.49-1.16] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	7p21.3	7	10661270	NA	MGC4859	NA	NA	ENSG00000283117	NA	NA	rs73678284-T	rs73678284	0	73678284	intron_variant	FALSE	NR	9e-6	5.045757490560675	(sleep latency)	0.2835	[0.16-0.41] unit decrease	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	8p22	8	18209886	NAT1, ASAH1, AACP, NAT2	NAT1	NA	NA	ENSG00000171428	NA	NA	rs7845127-C	rs7845127	0	7845127	non_coding_transcript_exon_variant	FALSE	NR	3e-6	5.522878745280337	(sleep latency)	0.2572	[0.15-0.37] unit decrease	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	8q21.3	8	91347109	SLC26A7, LRRC69, MIR4661	SLC26A7	NA	NA	ENSG00000147606	NA	NA	rs77942316-A	rs77942316	0	77942316	intron_variant	FALSE	NR	7e-7	6.154901959985743	(sleep latency)	0.8467	[0.51-1.18] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	8q21.3	8	91586775	RP11-122C21.1, SLC26A7	NA - RN7SKP231	NA	ENSG00000200151	NA	NA	8190	rs61134957-C	rs61134957	0	61134957	intron_variant	TRUE	NR	1e-6	6	(sleep latency)	0.751	[0.45-1.06] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	DMRT1, DMRT3, KANK1, DMRT2	NA	NA	NA	NA	NA	NA	chr9:864201-T	chr9:864201	0	NA	NA	TRUE	NR	3e-8	7.522878745280337	(sleep latency)	0.2938	[0.19-0.4] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	10p12.31	10	19146565	C10orf112	MALRD1	NA	NA	ENSG00000204740	NA	NA	rs2686656-A	rs2686656	0	2686656	intron_variant	FALSE	NR	6e-6	5.221848749616356	(sleep latency)	0.2982	[0.17-0.43] unit decrease	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	15q26.2	15	94088243	CTD-2643K12.3, MCTP2	LINC01581	NA	NA	ENSG00000259724	NA	NA	rs11074250-T	rs11074250	0	11074250	intron_variant	FALSE	NR	6e-6	5.221848749616356	(sleep latency)	0.2511	[0.14-0.36] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	20p13	20	527787	CSNK2A1, TBC1D20, TCF15, RBCK1	CSNK2A1	NA	NA	ENSG00000101266	NA	NA	rs74448913-A	rs74448913	0	74448913	intron_variant	FALSE	NR	8e-8	7.096910013008056	(sleep latency)	0.9822	[0.62-1.34] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	2p22.2	2	37727574	CDC42EP3, LINC00211, FAM82A1	CDC42EP3	NA	NA	ENSG00000163171	NA	NA	rs144261420-G	rs144261420	0	144261420	intron_variant	FALSE	NR	1e-6	6	(sleep latency, weekdays)	0.5179	[0.31-0.73] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	2q37.1	2	230444502	SP100, SP140L, HMGB1P3, SP140	SP100	NA	NA	ENSG00000067066	NA	NA	rs17273810-A	rs17273810	0	17273810	intron_variant	FALSE	NR	8e-6	5.096910013008056	(sleep latency, weekdays)	0.3877	[0.22-0.56] unit decrease	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3p26.1	3	6769634	GRM7-AS3, GRM7, MRPS36P1, GRM7-AS2	GRM7-AS3	NA	NA	ENSG00000226258	NA	NA	rs185934952-A	rs185934952	0	185934952	intron_variant	FALSE	NR	2e-6	5.698970004336019	(sleep latency, weekdays)	0.8564	[0.51-1.21] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3p13	3	70676751	HMGB1P36	NA - COX6CP6	NA	ENSG00000240156	NA	NA	74372	rs147786325-T	rs147786325	0	147786325	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(sleep latency, weekdays)	0.9523	[0.56-1.34] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	4q21.21	4	78121963	FRAS1, HMGB1P44, MRPL1	FRAS1	NA	NA	ENSG00000138759	NA	NA	rs6842385-A	rs6842385	0	6842385	intron_variant	FALSE	NR	3e-6	5.522878745280337	(sleep latency, weekdays)	0.8919	[0.52-1.26] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5p13.2	5	36377578	RANBP3L, RNA5SP181, NADKD1, NADKD1-AS1	RANBP3L - NA	ENSG00000164188	NA	NA	75464	NA	rs74541420-T	rs74541420	0	74541420	regulatory_region_variant	TRUE	NR	4e-6	5.3979400086720375	(sleep latency, weekdays)	0.4151	[0.24-0.59] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6q22.31	6	125548515	HEY2, NCOA7, HDDC2	NA	NA	NA	NA	NA	NA	rs74976558-T	rs74976558	1	9285455	intergenic_variant	TRUE	NR	6e-6	5.221848749616356	(sleep latency, weekdays)	0.3878	[0.22-0.56] unit decrease	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	RNU1-14P	NA	NA	NA	NA	NA	NA	chr7:53536734-AG	chr7:53536734	0	NA	NA	TRUE	NR	7e-6	5.154901959985743	(sleep latency, weekdays)	0.3269	[0.18-0.47] unit decrease	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	8p23.2	8	3921114	CSMD1, RNA5SP251	CSMD1	NA	NA	ENSG00000183117	NA	NA	rs62480124-C	rs62480124	0	62480124	intron_variant	FALSE	NR	3e-7	6.522878745280337	(sleep latency, weekdays)	0.946	[0.58-1.31] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	16p13.12	16	13751862	U95743.1, ERCC4, RPS26P52	NA	NA	NA	NA	NA	NA	rs12934187-T	rs12934187	0	12934187	intron_variant	TRUE	NR	6e-6	5.221848749616356	(sleep latency, weekdays)	0.6452	[0.37-0.92] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	17p12	17	15035627	AC005772.2, CDRT7, RPL23AP76, PMP22	CDRT7 - CDRT8	ENSG00000259944	ENSG00000265163	NA	3670	69610	rs9907309-G	rs9907309	0	9907309	intron_variant	TRUE	NR	5e-6	5.301029995663981	(sleep latency, weekdays)	0.2443	[0.14-0.35] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	17q22	17	55217411	HLF, STXBP4, MMD, COX11	STXBP4 - HLF	ENSG00000166263	ENSG00000108924	NA	43779	47549	rs79692461-G	rs79692461	0	79692461	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	(sleep latency, weekdays)	0.5106	[0.29-0.73] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	20p13	20	551613	CSNK2A1, TCF15, TBC1D20, SRXN1	CSNK2A1 - TCF15	ENSG00000101266	ENSG00000125878	NA	7778	52644	rs112815007-G	rs112815007	0	112815007	intergenic_variant	TRUE	NR	4e-7	6.3979400086720375	(sleep latency, weekdays)	1.041	[0.64-1.44] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	20p12.1	20	12488910	PA2G4P2	NA	NA	NA	NA	NA	NA	rs62217115-G	rs62217115	0	62217115	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(sleep latency, weekdays)	0.8833	[0.51-1.26] unit increase	Affymetrix [7141204] (imputed)	N	sleep latency	http://www.ebi.ac.uk/efo/EFO_0005280	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FVC)	48,943 European ancestry individuals.	57,176 European ancestry individuals, 38,199 individuals.	2q35	2	217818431	TNS1	TNS1	NA	NA	ENSG00000079308	NA	NA	rs2571445-G	rs2571445	0	2571445	missense_variant	FALSE	0.6001	1e-6	6	NA	0.033	[0.019-0.047] unit increase	Affymetrix [27624732] (imputed)	N	vital capacity	http://www.ebi.ac.uk/efo/EFO_0004312	GCST004184	Genome-wide genotyping array	0.6001	NA	0.033
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FVC)	48,943 European ancestry individuals.	57,176 European ancestry individuals, 38,199 individuals.	10p13	10	12236022	CDC123	CDC123	NA	NA	ENSG00000151465	NA	NA	rs7090277-A	rs7090277	0	7090277	intron_variant	FALSE	0.5158	5e-6	5.301029995663981	NA	0.03	[0.016-0.044] unit increase	Affymetrix [27624732] (imputed)	N	vital capacity	http://www.ebi.ac.uk/efo/EFO_0004312	GCST004184	Genome-wide genotyping array	0.5158	NA	0.03
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FVC)	48,943 European ancestry individuals.	57,176 European ancestry individuals, 38,199 individuals.	4q24	4	105767747	GSTCD	GSTCD, GSTCD-AS1, INTS12	NA	NA	ENSG00000138780, ENSG00000251175, ENSG00000138785	NA	NA	rs10516526-G	rs10516526	0	10516526	intron_variant	FALSE	0.0628	8e-6	5.096910013008056	NA	0.061	[0.034-0.088] unit increase	Affymetrix [27624732] (imputed)	N	vital capacity	http://www.ebi.ac.uk/efo/EFO_0004312	GCST004184	Genome-wide genotyping array	0.0628	NA	0.061
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	7p21.3	7	7246814	C1GALT1	C1GALT1	NA	NA	ENSG00000106392	NA	NA	rs10246303-T	rs10246303	0	10246303	3_prime_UTR_variant	FALSE	0.41	2e-8	7.698970004336019	NA	0.022	[0.014-0.03] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.41	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	5q33.3	5	157383064	CYFIP2	CYFIP2	NA	NA	ENSG00000055163	NA	NA	rs10515750-T	rs10515750	0	10515750	intron_variant	FALSE	0.0718	5e-13	12.301029995663981	(conditioned on rs1990950)	0.054	[0.04-0.068] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.0718	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	12q22	12	95160995	FGD6	FGD6	NA	NA	ENSG00000180263	NA	NA	rs113745635-T	rs113745635	0	113745635	intron_variant	FALSE	0.21	9e-18	17.045757490560675	NA	0.041	[0.031-0.051] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.21	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	17q12	17	38730575	CISD3	CISD3, CISD3	NA	NA	ENSG00000274768, ENSG00000277972	NA	NA	rs11658500-A	rs11658500	0	11658500	non_coding_transcript_exon_variant	FALSE	0.14	7e-11	10.154901959985743	NA	0.037	[0.025-0.049] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.14	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	1p22.1	1	91603410	CDC7, TGFBR3	WDR82P2 - HSP90B3P	ENSG00000241318	ENSG00000203914	NA	67817	39106	rs1192404-G	rs1192404	0	1192404	intergenic_variant	TRUE	0.16	6e-20	19.221848749616356	(conditioned on rs12140637)	0.048	[0.038-0.058] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.16	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	1p22.1	1	91908960	TGFBR3, BRDT2	TGFBR3 - BRDT	ENSG00000069702	ENSG00000137948	NA	2625	40383	rs12140637-T	rs12140637	0	12140637	intergenic_variant	TRUE	0.31	1e-9	9	NA	0.026	[0.018-0.034] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.31	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	15q23	15	71496048	THSD4	THSD4	NA	NA	ENSG00000187720	NA	NA	rs12591467-T	rs12591467	0	12591467	intron_variant	FALSE	0.68	6e-10	9.221848749616356	(conditioned on rs10851839)	0.026	[0.018-0.034] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.68	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	4q22.1	4	88894544	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs13110699-G	rs13110699	0	13110699	intron_variant	FALSE	0.82	8e-15	14.096910013008056	(conditioned on rs2045517)	0.038	[0.028-0.048] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.82	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	6q13	6	72960373	KCNQ5	KCNQ5	NA	NA	ENSG00000185760	NA	NA	rs141651520-?	rs141651520	0	141651520	intron_variant	FALSE	0.201	1e-17	17	NA	0.042	[0.032-0.052] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.201	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	3p14.3	3	55116650	CACNA2D3, WNT5A	CACNA2D3 - LINC02017	ENSG00000157445	ENSG00000243572	NA	42093	61522	rs1458979-G	rs1458979	0	1458979	intergenic_variant	TRUE	0.5	4e-10	9.397940008672037	NA	0.025	[0.017-0.033] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.5	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	5q11.2	5	52899203	ITGA1	ITGA1	NA	NA	ENSG00000213949	NA	NA	rs1551943-A	rs1551943	0	1551943	intron_variant	FALSE	0.23	2e-18	17.69897000433602	NA	0.041	[0.031-0.051] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.23	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	14q31.2	14	83843320	LINC01467, LINC00911	RNU6ATAC28P - LINC02305	ENSG00000238561	ENSG00000258532	NA	92819	60117	rs1698268-T	rs1698268	0	1698268	intergenic_variant	TRUE	0.29	3e-18	17.522878745280337	NA	0.025	[0.015-0.035] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.29	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	1p34.3	1	39570014	LOC101929516	PABPC4, PABPC4-AS1	NA	NA	ENSG00000090621, ENSG00000228060	NA	NA	rs17513135-T	rs17513135	0	17513135	intron_variant	FALSE	0.23	2e-16	15.698970004336019	NA	0.038	[0.028-0.048] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.23	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	3q21.3	3	128272684	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2811415-G	rs2811415	0	2811415	intron_variant	FALSE	0.84	6e-11	10.221848749616356	NA	0.035	[0.025-0.045] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.84	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	6p21.33	6	31588379	LST1	LST1, LST1, LST1, LST1, LST1, LST1, LST1	NA	NA	ENSG00000223465, ENSG00000234514, ENSG00000231048, ENSG00000206433, ENSG00000226182, ENSG00000204482, ENSG00000230791	NA	NA	rs28986170-?	rs28986170	0	28986170	non_coding_transcript_exon_variant	FALSE	0.752	2e-10	9.698970004336019	(conditioned on rs2070600, rs9272528)	0.063	[0.043-0.083] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.752	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	10p11.23	10	29978881	SVIL, KIAA1462	NA - JCAD	NA	ENSG00000165757	NA	NA	33922	rs3847402-A	rs3847402	0	3847402	intergenic_variant	TRUE	0.4057	8e-11	10.096910013008056	NA	0.027	[0.019-0.035] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.4057	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	3q26.2	3	168998020	LOC100507661, MECOM	LINC02082 - LINC01997	ENSG00000242268	ENSG00000241383	NA	73430	5002	rs56341938-?	rs56341938	0	56341938	intergenic_variant	TRUE	0.51	6e-14	13.221848749616356	NA	0.029	[0.021-0.037] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.51	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	2q37.3	2	238407919	TRAF3IP1, ASB1	TRAF3IP1 - RNU6-234P	ENSG00000204104	ENSG00000202099	NA	7022	4723	rs61332075-C	rs61332075	0	61332075	intergenic_variant	TRUE	0.12	3e-10	9.522878745280337	NA	0.038	[0.026-0.05] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.12	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	17q11.2	17	29936962	EFCAB5	EFCAB5	NA	NA	ENSG00000176927	NA	NA	rs62070270-G	rs62070270	0	62070270	intron_variant	FALSE	0.45	7e-18	17.154901959985743	NA	0.034	[0.026-0.042] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.45	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	15q25.2	15	83592938	SH3GL3	SH3GL3	NA	NA	ENSG00000140600	NA	NA	rs66650179-?	rs66650179	0	66650179	intron_variant	FALSE	0.81	4e-12	11.397940008672037	NA	0.042	[0.03-0.054] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.81	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	1q43	1	239687288	CHRM3	CHRM3	NA	NA	ENSG00000133019	NA	NA	rs6688537-A	rs6688537	0	6688537	intron_variant	FALSE	0.5	7e-22	21.154901959985743	NA	0.038	[0.03-0.046] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.5	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	7q22.1	7	100038344	ZKSCAN1	ZKSCAN1	NA	NA	ENSG00000106261	NA	NA	rs72615157-A	rs72615157	0	72615157	3_prime_UTR_variant	FALSE	0.16	2e-9	8.698970004336019	NA	0.032	[0.022-0.042] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.16	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	15q15.1	15	41685492	MGA	MGA	NA	NA	ENSG00000174197	NA	NA	rs72724130-T	rs72724130	0	72724130	intron_variant	FALSE	0.057	1e-9	9	NA	0.056	[0.038-0.074] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.057	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	5q31.1	5	132452642	C5orf56	IRF1-AS1, IRF1	NA	NA	ENSG00000197536, ENSG00000125347	NA	NA	rs7713065-C	rs7713065	0	7713065	intron_variant	FALSE	0.73	3e-11	10.522878745280337	NA	0.029	[0.021-0.037] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.73	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	15q23	15	71416731	NR	THSD4	NA	NA	ENSG00000187720	NA	NA	rs10083577-A	rs10083577	0	10083577	intron_variant	FALSE	0.09	3e-7	6.522878745280337	NA	0.059	[0.035-0.083] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.09	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	5q21.1	5	99007164	NR	LINC02062 - NA	ENSG00000248489	NA	NA	12151	NA	rs1501911-A	rs1501911	0	1501911	intergenic_variant	TRUE	0.61	6e-8	7.221848749616356	NA	0.022	[0.014-0.03] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.61	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	15q22.33	15	67175947	NR	SMAD3	NA	NA	ENSG00000166949	NA	NA	rs17294280-G	rs17294280	0	17294280	intron_variant	FALSE	0.26	3e-7	6.522878745280337	NA	0.024	[0.014-0.034] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.26	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	1q41	1	218515813	NR	LINC02869	NA	NA	ENSG00000228208	NA	NA	rs3009947-C	rs3009947	0	3009947	intron_variant	FALSE	0.51	5e-6	5.301029995663981	(conditioned on rs993925)	0.018	[0.01-0.026] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.51	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	2p14	2	64654863	NR	SERTAD2	NA	NA	ENSG00000179833	NA	NA	rs3755189-A	rs3755189	0	3755189	intron_variant	FALSE	0.45	2e-7	6.698970004336019	NA	0.021	[0.013-0.029] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.45	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	10q22.3	10	79558486	NR	SFTPA2	NA	NA	ENSG00000185303	NA	NA	rs61860558-T	rs61860558	0	61860558	intron_variant	FALSE	0.32	8e-8	7.096910013008056	NA	0.027	[0.017-0.037] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.32	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	3p21.1	3	53700168	NR	CACNA1D	NA	NA	ENSG00000157388	NA	NA	rs76798021-T	rs76798021	0	76798021	intron_variant	FALSE	0.21	2e-6	5.698970004336019	NA	0.023	[0.013-0.033] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.21	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	1p31.1	1	73881234	NR	NA - RNU4ATAC8P	NA	ENSG00000252005	NA	NA	2480	rs115523263-G	rs115523263	0	115523263	intron_variant	TRUE	0.02	1e-6	6	NA	1.423	[0.85-2] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.02	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	10p11.22	10	32172248	NR	RPS4XP11 - RNU7-22P	ENSG00000234335	ENSG00000252482	NA	68955	1436	rs200528172-?	rs200528172	0	200528172	intergenic_variant	TRUE	0.798	3e-6	5.522878745280337	NA	0.022	[0.012-0.032] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.798	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	4q31.21	4	144524627	HHIP	NA - KRT18P51	NA	ENSG00000250504	NA	NA	47611	rs138641402-T	rs138641402	0	138641402	intron_variant	TRUE	0.3808	5e-33	32.30102999566398	NA	0.082	[0.068-0.096] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.3808	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	6q24.2	6	142424746	LOC153910, GPR126	ADGRG6	NA	NA	ENSG00000112414	NA	NA	rs7753012-G	rs7753012	0	7753012	intron_variant	FALSE	0.3018	2e-31	30.69897000433602	NA	0.084	[0.07-0.098] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.3018	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	4q24	4	105897896	NPNT	NPNT	NA	NA	ENSG00000168743	NA	NA	rs34712979-A	rs34712979	0	34712979	splice_region_variant	FALSE	0.262	2e-31	30.69897000433602	NA	0.087	[0.073-0.101] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.262	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	6p21.32	6	32183666	AGER	AGER, AGER, AGER, AGER, AGER, AGER	NA	NA	ENSG00000204305, ENSG00000234729, ENSG00000230514, ENSG00000237405, ENSG00000206320, ENSG00000229058	NA	NA	rs2070600-T	rs2070600	0	2070600	missense_variant	FALSE	0.0634	3e-25	24.522878745280337	NA	0.14	[0.11-0.17] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.0634	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	15q23	15	71336031	THSD4	THSD4	NA	NA	ENSG00000187720	NA	NA	rs10851839-A	rs10851839	0	10851839	intron_variant	FALSE	0.6687	1e-24	24	NA	0.072	[0.058-0.086] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.6687	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	5q32	5	148476829	HTR4	HTR4	NA	NA	ENSG00000164270	NA	NA	rs7715901-G	rs7715901	0	7715901	intron_variant	FALSE	0.3957	8e-23	22.096910013008056	NA	0.066	[0.052-0.08] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.3957	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	6q24.2	6	142517036	GPR126	ADGRG6 - NA	ENSG00000112414	NA	NA	70770	NA	rs148274477-T	rs148274477	0	148274477	intergenic_variant	TRUE	0.0263	4e-17	16.397940008672037	NA	0.175	[0.13-0.22] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.0263	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	6p21.32	6	32667852	HLA-DQB1	HLA-DQB1, HLA-DQB1, HLA-DQB1	NA	NA	ENSG00000179344, ENSG00000206302, ENSG00000206237	NA	NA	rs114544105-A	rs114544105	1	3844313	intron_variant	FALSE	0.2698	5e-17	16.30102999566398	NA	0.063	[0.047-0.079] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.2698	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	10p13	10	12236022	CDC123	CDC123	NA	NA	ENSG00000151465	NA	NA	rs7090277-A	rs7090277	0	7090277	intron_variant	FALSE	0.5158	2e-16	15.698970004336019	NA	0.054	[0.04-0.068] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.5158	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	2q36.3	2	228637787	PID1	LINC01807	NA	NA	ENSG00000232023	NA	NA	rs10498230-T	rs10498230	0	10498230	intron_variant	FALSE	0.0793	9e-12	11.045757490560675	NA	0.083	[0.059-0.107] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.0793	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	4q22.1	4	88949813	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs2045517-T	rs2045517	0	2045517	intron_variant	FALSE	0.4069	1e-11	11	NA	0.046	[0.032-0.06] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.4069	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	5q33.3	5	157493748	ADAM19	ADAM19	NA	NA	ENSG00000135074	NA	NA	rs1990950-T	rs1990950	0	1990950	intron_variant	FALSE	0.3906	3e-11	10.522878745280337	NA	0.045	[0.031-0.059] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.3906	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	6q21	6	108949453	ARMC2	ARMC2	NA	NA	ENSG00000118690	NA	NA	rs2768551-A	rs2768551	0	2768551	intron_variant	FALSE	0.191	6e-11	10.221848749616356	NA	0.055	[0.039-0.071] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.191	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	1p36.13	1	16980180	MFAP2	MFAP2	NA	NA	ENSG00000117122	NA	NA	rs2284746-G	rs2284746	0	2284746	intron_variant	FALSE	0.5218	1e-10	10	NA	0.042	[0.028-0.056] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.5218	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.2	16	8343360	NR	LINC02152 - N/A; No mapped genes	NA	NA	NA	NA	NA	rs40388-G; rs40387-A	rs40388; rs40387	0	NA	intron_variant; intron_variant	NA	0.4	3e-9	8.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.4	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.2	16	9461512	NR	LINC01195 - N/A; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7202570-A; rs1428801-C; rs12448291-T; rs2192636-C; rs1428804-T; rs9933124-C; rs16965266-T; rs16965263-A; rs1428795-C; rs2304474-G; rs1476960-G; rs16965282-A; rs11640563-G	rs7202570; rs1428801; rs12448291; rs2192636; rs1428804; rs9933124; rs16965266; rs16965263; rs1428795; rs2304474; rs1476960; rs16965282; rs11640563	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.037	2e-7	6.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.037	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.13	16	10802912	NR	TVP23A; No mapped genes	NA	NA	NA	NA	NA	rs9745621-T; rs11074926-C	rs9745621; rs11074926	0	NA	intron_variant; intron_variant	NA	0.0	8e-7	6.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.13	16	11514854	NR	N/A - LITAF; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs9932802-A; rs8050631-G; rs4545838-G; rs7189101-A	rs9932802; rs8050631; rs4545838; rs7189101	0	NA	intron_variant; intron_variant; intron_variant; missense_variant	NA	0.0	3e-6	5.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p13.11	16;16	15851172;15856735	NR	MYH11; MYH11; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs215570-C; rs3851705-A; rs12923604-G; rs9922682-C; rs9933417-C; rs3851702-T; rs3851703-G	rs215570; rs3851705; rs12923604; rs9922682; rs9933417; rs3851702; rs3851703	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.089	1e-6	6	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.089	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.3	16	17112088	NR	XYLT1; No mapped genes	NA	NA	NA	NA	NA	rs4453460-C; rs4583225-G	rs4453460; rs4583225	0	NA	intron_variant; intron_variant	NA	0.052	3e-10	9.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.052	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.3	16	17112088	NR	XYLT1; No mapped genes	NA	NA	NA	NA	NA	rs4453460-A; rs4583225-G	rs4453460; rs4583225	0	NA	intron_variant; intron_variant	NA	0.231	5e-9	8.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.231	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.3	16	20325269	NR	GP2; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs8046269-T; rs12930599-A; rs11642182-G; rs9937721-C; rs4383154-G	rs8046269; rs12930599; rs11642182; rs9937721; rs4383154	0	NA	intron_variant; synonymous_variant; 3_prime_UTR_variant; intergenic_variant; intron_variant	NA	0.225	2e-10	9.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.225	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.3	16	20325269	NR	GP2; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs8046269-T; rs12930599-G; rs11642182-G; rs9937721-C; rs4383154-G	rs8046269; rs12930599; rs11642182; rs9937721; rs4383154	0	NA	intron_variant; synonymous_variant; 3_prime_UTR_variant; intergenic_variant; intron_variant	NA	0.23	7e-8	7.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.23	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.3	16	20489224	NR	ACSM2A - ACSM2B; No mapped genes	NA	NA	NA	NA	NA	rs7500220-G; rs2355918-A	rs7500220; rs2355918	0	NA	non_coding_transcript_exon_variant; intergenic_variant	NA	0.005	3e-8	7.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.005	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.1	16;16;16	24761359;24799360;24777324	NR	TNRC6A; No mapped genes; TNRC6A; TNRC6A; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1465423-C; rs2112783-A; rs17177078-C; rs11639856-A; rs2287786-G; rs3803716-C; rs2059134-G; rs8055590-C; rs8050047-C; rs13336754-C; rs2112784-G; rs12599552-T; rs12596320-C; rs6497755-A	rs1465423; rs2112783; rs17177078; rs11639856; rs2287786; rs3803716; rs2059134; rs8055590; rs8050047; rs13336754; rs2112784; rs12599552; rs12596320; rs6497755	0	NA	intron_variant; intron_variant; intron_variant; missense_variant; intron_variant; missense_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; missense_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	7e-13	12.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.1	16;16;16	24761359;24799360;24777324	NR	TNRC6A; No mapped genes; TNRC6A; TNRC6A; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1465423-C; rs2112783-A; rs17177078-C; rs11639856-A; rs2287786-G; rs3803716-T; rs2059134-G; rs8055590-C; rs8050047-C; rs13336754-C; rs2112784-G; rs12599552-T; rs12596320-C; rs6497755-A	rs1465423; rs2112783; rs17177078; rs11639856; rs2287786; rs3803716; rs2059134; rs8055590; rs8050047; rs13336754; rs2112784; rs12599552; rs12596320; rs6497755	0	NA	intron_variant; intron_variant; intron_variant; missense_variant; intron_variant; missense_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; missense_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.154	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.154	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.1	16	25986289	NR	HS3ST4; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11074740-A; rs7190163-C; rs4412975-A; rs7191801-C; rs7196247-A; rs11074738-C; rs11645216-G; rs11644086-G; rs4430747-T; rs7191950-T; rs7196918-G	rs11074740; rs7190163; rs4412975; rs7191801; rs7196247; rs11074738; rs11645216; rs11644086; rs4430747; rs7191950; rs7196918	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.003	6e-9	8.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.003	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.1	16	25986289	NR	HS3ST4; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11074740-A; rs7190163-C; rs4412975-G; rs7191801-C; rs7196247-A; rs11074738-C; rs11645216-G; rs11644086-G; rs4430747-T; rs7191950-T; rs7196918-G	rs11074740; rs7190163; rs4412975; rs7191801; rs7196247; rs11074738; rs11645216; rs11644086; rs4430747; rs7191950; rs7196918	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.086	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.086	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.1	16	26634658	NR	LINC02195 - N/A; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7192315-T; rs237144-A; rs237142-G; rs12162084-G; rs237143-C	rs7192315; rs237144; rs237142; rs12162084; rs237143	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.007	5e-29	28.30102999566398	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.007	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.1	16	26634658	NR	LINC02195 - N/A; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7192315-T; rs237144-C; rs237142-G; rs12162084-G; rs237143-C	rs7192315; rs237144; rs237142; rs12162084; rs237143	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.349	2e-14	13.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.349	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.1	16	27057005	NR	N/A - C16orf82; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2037175-C; rs7184516-G; rs11865815-G	rs2037175; rs7184516; rs11865815	0	NA	intergenic_variant; intergenic_variant; intergenic_variant	NA	0.464	4e-28	27.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.464	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.1	16	27057005	NR	N/A - C16orf82; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2037175-C; rs7184516-G; rs11865815-T	rs2037175; rs7184516; rs11865815	0	NA	intergenic_variant; intergenic_variant; intergenic_variant	NA	0.314	2e-14	13.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.314	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.1	16;16	28311016;28325561	NR	SBK1; SBK1 - NPIPB6	NA	NA	NA	NA	NA	rs4787451-G; rs2726034-C	rs4787451; rs2726034	0	NA	intron_variant; intergenic_variant	NA	0.263	5e-13	12.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.263	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p12.1	16;16	28311016;28325561	NR	SBK1; SBK1 - NPIPB6	NA	NA	NA	NA	NA	rs4787451-G; rs2726034-T	rs4787451; rs2726034	0	NA	intron_variant; intergenic_variant	NA	0.73	1e-10	10	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.73	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p11.2, 16p12.1	16;16	28517302;28479196	NR	IL27 - NUPR1; CLN3	NA	NA	NA	NA	NA	rs153103-C; rs151181-T	rs153103; rs151181	0	NA	intron_variant; intron_variant	NA	0.473	9e-6	5.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.473	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p11.2	16	31357553	NR	ITGAX; No mapped genes	NA	NA	NA	NA	NA	rs11574637-C; rs11150619-T	rs11574637; rs11150619	0	NA	missense_variant; intron_variant	NA	0.182	8e-8	7.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.182	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16p11.2	16	31357553	NR	ITGAX; No mapped genes	NA	NA	NA	NA	NA	rs11574637-T; rs11150619-T	rs11574637; rs11150619	0	NA	missense_variant; intron_variant	NA	0.444	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.444	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16q12.1	16	48284817	NR	LONP2; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs13336771-C; rs10521168-A; rs11076560-A; rs12446160-A; rs9940038-T; rs13336625-G; rs16946122-C; rs11076561-A; rs11076565-A; rs11076564-A; rs9941123-C; rs16945972-A; rs8055764-G; rs9926192-G; rs17822931-T; rs8043685-G; rs13335504-C; rs13330082-T; rs9933211-A; rs9932328-A; rs17825174-G	rs13336771; rs10521168; rs11076560; rs12446160; rs9940038; rs13336625; rs16946122; rs11076561; rs11076565; rs11076564; rs9941123; rs16945972; rs8055764; rs9926192; rs17822931; rs8043685; rs13335504; rs13330082; rs9933211; rs9932328; rs17825174	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; missense_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.111	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.111	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	16q12.1	16	51714324	NR	RN7SKP142 - LINC01571; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4606717-G; rs9925751-C; rs1381452-T; rs7194086-A; rs1585528-T; rs8061041-G	rs4606717; rs9925751; rs1381452; rs7194086; rs1585528; rs8061041	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.001	9e-18	17.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.001	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	SMOX	NA	NA	NA	NA	NA	NA	chr20:4157072-G	chr20:4157072	0	NA	NA	TRUE	0.3878	0	355	NA	0.1490442	[0.14-0.16] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.3878	NA	0.1490442
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	20p12.2	20	10739131	RP11-103J8.1	LINC01752	NA	NA	ENSG00000224961	NA	NA	rs6040116-T	rs6040116	0	6040116	intron_variant	FALSE	0.0736	6e-12	11.221848749616356	NA	0.04727759	[0.034-0.061] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0736	NA	0.04727759
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	20q11.21	20	32519596	C20orf112	NOL4L	NA	NA	ENSG00000197183	NA	NA	rs6141743-G	rs6141743	0	6141743	non_coding_transcript_exon_variant	FALSE	0.2265	3e-11	10.522878745280337	NA	0.02855631	[0.02-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.2265	NA	0.02855631
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	20q12	20	39934603	HSPE1P1	HSPE1P1 - LINC01370	ENSG00000234878	ENSG00000237767	NA	1364	69613	rs2145943-G	rs2145943	0	2145943	intergenic_variant	TRUE	0.4078	3e-20	19.522878745280337	NA	0.03386097	[0.027-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.4078	NA	0.03386097
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	20q13.2	20	53613492	AC005808.3	ZNF217 - RNU7-14P	ENSG00000171940	ENSG00000238468	NA	3585	55205	rs145910606-T	rs145910606	0	145910606	intron_variant	TRUE	0.0174	1e-19	19	NA	0.132824	[0.1-0.16] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0174	NA	0.132824
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	20q13.31	20	57169375	BMP7	BMP7	NA	NA	ENSG00000101144	NA	NA	rs117553902-T	rs117553902	0	117553902	3_prime_UTR_variant	FALSE	0.0024	7e-13	12.154901959985743	NA	0.2905123	[0.21-0.37] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0024	NA	0.2905123
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	RBM38, RP4-800J21.3	NA	NA	NA	NA	NA	NA	chr20:55966904-T	chr20:55966904	0	NA	NA	TRUE	0.1917	1e-24	24	NA	0.04652067	[0.038-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1917	NA	0.04652067
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	TUBB1	NA	NA	NA	NA	NA	NA	chr20:57594684-T	chr20:57594684	0	NA	NA	TRUE	0.0476	3e-9	8.522878745280337	NA	0.04970384	[0.033-0.066] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.0476	NA	0.04970384
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	NA	NA	NA	LTN1	NA	NA	NA	NA	NA	NA	chr21:30339120-A	chr21:30339120	0	NA	NA	TRUE	0.1509	3e-9	8.522878745280337	NA	0.02967759	[0.02-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1509	NA	0.02967759
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	22q11.21	22	21563161	UBE2L3	UBE2L3	NA	NA	ENSG00000185651	NA	NA	rs131656-A	rs131656	0	131656	intron_variant	FALSE	0.1912	6e-16	15.221848749616356	NA	0.03695907	[0.028-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.1912	NA	0.03695907
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	22q12.2	22	29237837	EMID1	EMID1	NA	NA	ENSG00000186998	NA	NA	rs5752882-T	rs5752882	0	5752882	intron_variant	FALSE	0.5641	3e-12	11.522878745280337	NA	0.02568261	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5641	NA	0.02568261
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte percentage of red cells	170,763 European ancestry individuals	NA	22q12.2	22	29397536	AP1B1	AP1B1 - RFPL4AP6	ENSG00000100280	ENSG00000278292	NA	8953	35408	rs2267137-C	rs2267137	0	2267137	intron_variant	TRUE	0.5609	2e-10	9.698970004336019	NA	0.02315204	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004612	Genome-wide genotyping array	0.5609	NA	0.02315204
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1p36.32	1	3768390	CCDC27	CCDC27	NA	NA	ENSG00000162592	NA	NA	rs1181870-A	rs1181870	0	1181870	intron_variant	FALSE	0.2394	2e-14	13.698970004336019	NA	0.03207646	[0.024-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2394	NA	0.03207646
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1p34.1	1	45607817	NASP	NASP	NA	NA	ENSG00000132780	NA	NA	rs2230657-A	rs2230657	0	2230657	synonymous_variant	FALSE	0.4677	3e-13	12.522878745280337	NA	0.02592878	[0.019-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.4677	NA	0.02592878
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1q22	1	155208991	MTX1	THBS3, MTX1	NA	NA	ENSG00000169231, ENSG00000173171	NA	NA	rs760077-T	rs760077	0	760077	missense_variant	FALSE	0.6031	6e-19	18.221848749616356	NA	0.03218822	[0.025-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.6031	NA	0.03218822
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1q23.3	1	161653235	FCGR2B	FCGR3B - FCGR2B	ENSG00000162747	ENSG00000072694	NA	21272	9912	rs61804164-C	rs61804164	0	61804164	intergenic_variant	TRUE	0.1269	4e-11	10.397940008672037	NA	0.0362632	[0.025-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.1269	NA	0.0362632
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1q24.3	1	172171408	DNM3	DNM3	NA	NA	ENSG00000197959	NA	NA	rs554019-T	rs554019	0	554019	intron_variant	FALSE	0.4168	4e-9	8.397940008672037	NA	0.02124103	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.4168	NA	0.02124103
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1q32.1	1	203691653	ATP2B4	ATP2B4	NA	NA	ENSG00000058668	NA	NA	rs4951074-G	rs4951074	0	4951074	intron_variant	FALSE	0.901	6e-11	10.221848749616356	NA	0.03888983	[0.027-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.901	NA	0.03888983
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1q32.3	1	213793544	RP11-323I1.1	NA - PROX1-AS1	NA	ENSG00000230461	NA	NA	24207	rs10494964-C	rs10494964	0	10494964	intron_variant	TRUE	0.272	2e-9	8.698970004336019	NA	0.02452032	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.272	NA	0.02452032
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1q32.3	1	214004080	PROX1	PROX1	NA	NA	ENSG00000117707	NA	NA	rs6665764-A	rs6665764	0	6665764	intron_variant	FALSE	0.2607	6e-18	17.221848749616356	NA	0.03499522	[0.027-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2607	NA	0.03499522
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1q42.2	1	231335026	EXOC8	EXOC8	NA	NA	ENSG00000116903	NA	NA	rs11122272-G	rs11122272	0	11122272	3_prime_UTR_variant	FALSE	0.6284	4e-13	12.397940008672037	NA	0.02665634	[0.019-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.6284	NA	0.02665634
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1q42.2	1	231422308	EGLN1	EGLN1 - SNRPD2P2	ENSG00000135766	ENSG00000223982	NA	21	53648	rs533281866-C	rs533281866	0	533281866	intron_variant	TRUE	0.0215	2e-24	23.69897000433602	NA	0.1277725	[0.1-0.15] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0215	NA	0.1277725
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	1q44	1	247876149	TRIM58	TRIM58	NA	NA	ENSG00000162722	NA	NA	rs3811444-T	rs3811444	0	3811444	missense_variant	FALSE	0.336	1e-9	9	NA	0.02286733	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.336	NA	0.02286733
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	2p24.1	2	23674855	KLHL29	KLHL29	NA	NA	ENSG00000119771	NA	NA	rs56262900-A	rs56262900	0	56262900	intron_variant	FALSE	0.1027	2e-10	9.698970004336019	NA	0.03746084	[0.026-0.049] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.1027	NA	0.03746084
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	2p21	2	46066687	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs114948639-T	rs114948639	0	114948639	intron_variant	FALSE	0.0127	3e-15	14.522878745280337	NA	0.1283579	[0.096-0.16] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0127	NA	0.1283579
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	2p21	2	46125187	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs17799476-G	rs17799476	0	17799476	intron_variant	FALSE	0.1818	2e-9	8.698970004336019	NA	0.02782749	[0.019-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.1818	NA	0.02782749
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	2p21	2	46126027	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs10495928-G	rs10495928	0	10495928	intron_variant	FALSE	0.336	1e-85	85	NA	0.07334059	[0.066-0.081] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.336	NA	0.07334059
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	2p21	2	46803224	intergenic	LINC01118	NA	NA	ENSG00000222005	NA	NA	rs17773190-G	rs17773190	0	17773190	intron_variant	FALSE	0.4839	4e-11	10.397940008672037	NA	0.02370633	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.4839	NA	0.02370633
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	2q14.1	2	113207623	PSD4	PSD4	NA	NA	ENSG00000125637	NA	NA	rs7560180-T	rs7560180	0	7560180	3_prime_UTR_variant	FALSE	0.2208	1e-17	17	NA	0.03704176	[0.029-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2208	NA	0.03704176
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	2q14.2	2	121238062	TFCP2L1	TFCP2L1	NA	NA	ENSG00000115112	NA	NA	rs11689538-C	rs11689538	0	11689538	intron_variant	FALSE	0.1402	1e-11	11	NA	0.03471895	[0.025-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.1402	NA	0.03471895
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	2q22.3	2	145025715	TEX41	TEX41	NA	NA	ENSG00000226674	NA	NA	rs2246363-A	rs2246363	0	2246363	intron_variant	FALSE	0.747	1e-9	9	NA	0.02472458	[0.017-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.747	NA	0.02472458
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	2q33.3	2	207138855	KLF7	KLF7	NA	NA	ENSG00000118263	NA	NA	rs768090-T	rs768090	0	768090	intron_variant	FALSE	0.68	1e-10	10	NA	0.02474935	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.68	NA	0.02474935
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	2q35	2	218693015	STK36	STK36	NA	NA	ENSG00000163482	NA	NA	rs2303566-A	rs2303566	0	2303566	intron_variant	FALSE	0.4469	2e-11	10.698970004336019	NA	0.02393051	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.4469	NA	0.02393051
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	3p25.2	3	12326734	PPARG	PPARG	NA	NA	ENSG00000132170	NA	NA	rs4073770-T	rs4073770	0	4073770	intron_variant	FALSE	0.2482	1e-9	9	NA	0.02517588	[0.017-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2482	NA	0.02517588
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	3p21.1	3	52533601	NT5DC2	NT5DC2	NA	NA	ENSG00000168268	NA	NA	rs66782572-G	rs66782572	0	66782572	missense_variant	FALSE	0.5386	6e-9	8.221848749616356	NA	0.02063169	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5386	NA	0.02063169
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	3p14.3	3	56710234	intergenic	TASOR - ARHGEF3	ENSG00000163946	ENSG00000163947	NA	26969	17184	rs149804345-AAAAAAC	rs149804345	0	149804345	intergenic_variant	TRUE	0.3097	3e-16	15.522878745280337	NA	0.03165101	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.3097	NA	0.03165101
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	3p14.3	3	58471084	intergenic	PDHB - KCTD6	ENSG00000168291	ENSG00000168301	NA	37227	21012	rs11719450-T	rs11719450	0	11719450	intergenic_variant	TRUE	0.3716	2e-9	8.698970004336019	NA	0.02204239	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.3716	NA	0.02204239
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	3p13	3	69792729	MITF	MITF	NA	NA	ENSG00000187098	NA	NA	rs17006441-A	rs17006441	0	17006441	intron_variant	FALSE	0.4209	4e-10	9.397940008672037	NA	0.02257725	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.4209	NA	0.02257725
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	3q29	3	194785474	AC090505.6	LINC01968	NA	NA	ENSG00000237222	NA	NA	rs34477782-A	rs34477782	0	34477782	intron_variant	FALSE	0.595	2e-10	9.698970004336019	NA	0.02333744	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.595	NA	0.02333744
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	3q29	3	194956076	intergenic	NA	NA	NA	NA	NA	NA	rs35060063-A	rs35060063	0	35060063	intergenic_variant	TRUE	0.5024	5e-10	9.301029995663981	NA	0.02207133	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5024	NA	0.02207133
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	4q12	4	54542708	intergenic	LINC02283 - LINC02260	ENSG00000248184	ENSG00000250456	NA	186754	60503	rs218264-T	rs218264	0	218264	intergenic_variant	TRUE	0.2525	2e-16	15.698970004336019	NA	0.03395222	[0.026-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2525	NA	0.03395222
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	4q21.1	4	76451926	SHROOM3	SHROOM3	NA	NA	ENSG00000138771	NA	NA	rs2870238-T	rs2870238	0	2870238	intron_variant	FALSE	0.502	2e-12	11.698970004336019	NA	0.02483924	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.502	NA	0.02483924
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	4q22.1	4	87109109	AFF1	AFF1	NA	NA	ENSG00000172493	NA	NA	rs442177-T	rs442177	0	442177	intron_variant	FALSE	0.5937	1e-17	17	NA	0.03088176	[0.024-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5937	NA	0.03088176
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	NA	NA	NA	SLC39A8	NA	NA	NA	NA	NA	NA	chr4:103188709-T	chr4:103188709	0	NA	NA	TRUE	0.075	6e-13	12.221848749616356	NA	0.04851685	[0.035-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.075	NA	0.04851685
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	4q26	4	114647874	UGT8	UGT8	NA	NA	ENSG00000174607	NA	NA	rs6841433-G	rs6841433	0	6841433	intron_variant	FALSE	0.1822	1e-9	9	NA	0.02794617	[0.019-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.1822	NA	0.02794617
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	5p15.33	5	457146	EXOC3	EXOC3	NA	NA	ENSG00000180104	NA	NA	rs11749327-A	rs11749327	0	11749327	non_coding_transcript_exon_variant	FALSE	0.3062	5e-9	8.301029995663981	NA	0.02272517	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.30620000000000003	NA	0.02272517
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	5p13.2	5	34507680	intergenic	NA	NA	NA	NA	NA	NA	rs972761-C	rs972761	0	972761	intergenic_variant	TRUE	0.4664	3e-12	11.522878745280337	NA	0.02520453	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.4664	NA	0.02520453
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	5p13.1	5	40620480	intergenic	TTC33	NA	NA	ENSG00000113638	NA	NA	rs4957325-T	rs4957325	0	4957325	intron_variant	FALSE	0.8815	8e-9	8.096910013008056	NA	0.03183541	[0.021-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.8815	NA	0.03183541
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	5q13.3	5	77184008	intergenic	ZBED3-AS1 - PDE8B	ENSG00000250802	ENSG00000113231	NA	17099	26441	rs2928166-C	rs2928166	0	2928166	intron_variant	TRUE	0.1277	3e-12	11.522878745280337	NA	0.03737965	[0.027-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.1277	NA	0.03737965
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	5q35.3	5	177371039	RGS14	RGS14	NA	NA	ENSG00000169220	NA	NA	rs56235845-G	rs56235845	0	56235845	splice_region_variant	FALSE	0.3292	1e-9	9	NA	0.02294702	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.3292	NA	0.02294702
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	6p22.1	6	27492144	ZKSCAN3	ZNF184 - HNRNPA1P1	ENSG00000096654	ENSG00000218347	NA	19026	30932	rs34864796-A	rs34864796	0	34864796	intron_variant	TRUE	0.1274	4e-10	9.397940008672037	NA	0.062	[0.042-0.082] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.1274	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	16q23.1	16	75433123	CFDP1	CFDP1	NA	NA	ENSG00000153774	NA	NA	rs3743609-C	rs3743609	0	3743609	intron_variant	FALSE	0.5907	4e-10	9.397940008672037	NA	0.042	[0.028-0.056] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.5907	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	6p21.33	6	31600692	NCR3	NCR3 - UQCRHP1	ENSG00000237808	ENSG00000229189	NA	7686	10391	rs2857595-A	rs2857595	0	2857595	intergenic_variant	TRUE	0.213	4e-9	8.397940008672037	NA	0.048	[0.032-0.064] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.213	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	2p24.2	2	18127866	KCNS3	KCNS3	NA	NA	ENSG00000170745	NA	NA	rs62126408-C	rs62126408	0	62126408	intron_variant	FALSE	0.1411	8e-9	8.096910013008056	NA	0.055	[0.035-0.075] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.1411	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	4q24	4	105143470	TET2	NA - TET2	NA	ENSG00000168769	NA	NA	2405	rs34480284-A	rs34480284	0	34480284	intergenic_variant	TRUE	0.3737	1e-8	8	NA	0.039	[0.025-0.053] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.3737	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	2q35	2	217818431	TNS1	TNS1	NA	NA	ENSG00000079308	NA	NA	rs2571445-G	rs2571445	0	2571445	missense_variant	FALSE	0.6001	5e-8	7.301029995663981	NA	0.037	[0.023-0.051] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.6001	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	12q23.1	12	95861926	CCDC38	SNRPF	NA	NA	ENSG00000139343	NA	NA	rs12820313-C	rs12820313	0	12820313	intron_variant	FALSE	0.7931	5e-8	7.301029995663981	NA	0.044	[0.028-0.06] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.7931	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	NA	NA	NA	KCNE2	NA	NA	NA	NA	NA	NA	rs2834440-A	rs2834440	0	2834440	intron_variant	TRUE	0.6159	2e-7	6.698970004336019	NA	0.036	[0.022-0.05] unit increase	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.6159	NA	NA
2017-06-16	28166213	Wain LV	2017-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28166213	Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.	Lung function (FEV1/FVC)	48,943 European ancestry individuals	57,176 European ancestry individuals, 38,199 individuals.	9q33.1	9	116639371	ASTN2	ASTN2	NA	NA	ENSG00000148219	NA	NA	rs803923-A	rs803923	0	803923	intron_variant	FALSE	0.5395	4e-7	6.3979400086720375	NA	0.033	[0.019-0.047] unit decrease	Affymetrix [27624732] (imputed)	N	FEV/FEC ratio	http://www.ebi.ac.uk/efo/EFO_0004713	GCST004185	Genome-wide genotyping array	0.5395	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	105882525	Intergenic	INTS12	NA	NA	ENSG00000138785	NA	NA	rs185538822-A	rs185538822	0	185538822	intron_variant	FALSE	0.936	4e-6	5.3979400086720375	NA	0.092	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.936	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88804354	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs75581102-A	rs75581102	0	75581102	intron_variant	FALSE	0.064	3e-6	5.522878745280337	NA	0.091	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.064	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	17q24.1	17	65795365	CEP112	CEP112	NA	NA	ENSG00000154240	NA	NA	rs8079658-A	rs8079658	0	8079658	intron_variant	FALSE	0.793	5e-6	5.301029995663981	(AA)	0.091	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.793	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88796147	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs77140172-A	rs77140172	0	77140172	intron_variant	FALSE	0.064	3e-6	5.522878745280337	NA	0.09	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.064	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88801349	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs74811486-T	rs74811486	0	74811486	intron_variant	FALSE	0.064	3e-6	5.522878745280337	NA	0.09	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.064	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	105703345	INTS12	ARHGEF38, INTS12	NA	NA	ENSG00000236699, ENSG00000138785	NA	NA	rs72671826-T	rs72671826	0	72671826	intron_variant	FALSE	0.939	5e-6	5.301029995663981	NA	0.09	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.939	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78567268	CHRNA5	CHRNA5	NA	NA	ENSG00000169684	NA	NA	rs190065944-A	rs190065944	0	190065944	intron_variant	FALSE	0.27	4e-12	11.397940008672037	NA	0.089	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.27	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88797162	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs112542013-T	rs112542013	0	112542013	intron_variant	FALSE	0.063	3e-6	5.522878745280337	NA	0.089	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.063	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88785771	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs6847567-T	rs6847567	0	6847567	intron_variant	FALSE	0.063	3e-6	5.522878745280337	NA	0.089	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.063	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	1q41	1	218493087	Intergenic	LINC02869	NA	NA	ENSG00000228208	NA	NA	rs6656288-A	rs6656288	0	6656288	intron_variant	FALSE	0.918	6e-7	6.221848749616356	NA	0.088	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.918	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88953220	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs147089648-T	rs147089648	0	147089648	intron_variant	FALSE	0.083	6e-7	6.221848749616356	NA	0.087	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.083	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	105725192	GSTCD	INTS12, GSTCD	NA	NA	ENSG00000138785, ENSG00000138780	NA	NA	rs72671852-A	rs72671852	0	72671852	intron_variant	FALSE	0.939	5e-6	5.301029995663981	NA	0.085	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.939	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78606661	CHRNA3	CHRNA3	NA	NA	ENSG00000080644	NA	NA	rs56077333-A	rs56077333	0	56077333	intron_variant	FALSE	0.318	5e-18	17.30102999566398	NA	0.084	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.318	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78608566	CHRNA3	CHRNA3	NA	NA	ENSG00000080644	NA	NA	rs147144681-T	rs147144681	0	147144681	intron_variant	FALSE	0.312	6e-17	16.221848749616356	NA	0.084	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.312	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78608308	CHRNA3	CHRNA3	NA	NA	ENSG00000080644	NA	NA	rs147499554-T	rs147499554	1	111704647	intron_variant	FALSE	0.301	5e-16	15.301029995663981	NA	0.084	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.301	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144524627	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	47611	rs138641402-A	rs138641402	0	138641402	intron_variant	TRUE	0.668	9e-15	14.045757490560675	NA	0.083	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.668	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	1q41	1	218472531	Intergenic	LINC02869	NA	NA	ENSG00000228208	NA	NA	rs7526672-T	rs7526672	0	7526672	intron_variant	FALSE	0.754	6e-8	7.221848749616356	NA	0.083	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.754	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78733935	Intergenic	CHRNB4 - ADAMTS7	ENSG00000117971	ENSG00000136378	NA	6181	25271	rs3971859-T	rs3971859	0	3971859	non_coding_transcript_exon_variant	TRUE	0.24	3e-7	6.522878745280337	NA	0.082	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.24	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78608771	CHRNA3	CHRNA3	NA	NA	ENSG00000080644	NA	NA	rs114205691-T	rs114205691	1	113931022	intron_variant	FALSE	0.334	1e-17	17	NA	0.08	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.334	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78594605	CHRNA3	CHRNA3, CHRNA5	NA	NA	ENSG00000080644, ENSG00000169684	NA	NA	rs4887067-A	rs4887067	0	4887067	3_prime_UTR_variant	FALSE	0.346	5e-15	14.301029995663981	NA	0.079	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.346	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78606381	CHRNA3	CHRNA3	NA	NA	ENSG00000080644	NA	NA	rs12914385-T	rs12914385	0	12914385	intron_variant	FALSE	0.626	1e-17	17	NA	0.078	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.626	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78574103	CHRNA5	CHRNA5	NA	NA	ENSG00000169684	NA	NA	rs140330585-A	rs140330585	0	140330585	intron_variant	FALSE	0.337	1e-15	15	NA	0.078	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.337	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78586199	CHRNA5	CHRNA5	NA	NA	ENSG00000169684	NA	NA	rs951266-A	rs951266	0	951266	intron_variant	FALSE	0.596	1e-15	15	NA	0.078	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.596	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78570111	CHRNA5	CHRNA5	NA	NA	ENSG00000169684	NA	NA	rs7172118-A	rs7172118	0	7172118	intron_variant	FALSE	0.336	2e-15	14.698970004336019	NA	0.078	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.336	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78585039	CHRNA5	CHRNA5	NA	NA	ENSG00000169684	NA	NA	rs56390833-A	rs56390833	0	56390833	intron_variant	FALSE	0.333	2e-15	14.698970004336019	NA	0.078	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.333	NA	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	18q21.2	18	54435393	chr18mb51	CUPIN1P - NA	ENSG00000283613	NA	NA	10761	NA	rs7243790-G	rs7243790	0	7243790	intergenic_variant	TRUE	0.431547678	8e-7	6.096910013008056	NA	0.1365	[0.082-0.191] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.431547678	NA	0.1365
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	12p12.2	12	20125496	PDE3A	LINC02468	NA	NA	ENSG00000256499	NA	NA	rs2303658-A	rs2303658	0	2303658	intron_variant	FALSE	0.319920217	2e-6	5.698970004336019	NA	0.1367	[0.08-0.193] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.319920217	NA	0.1367
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6q24.2	6	142872207	chr6mb143	HIVEP2	NA	NA	ENSG00000010818	NA	NA	rs9390025-C	rs9390025	0	9390025	intron_variant	FALSE	0.303969989	4e-6	5.3979400086720375	NA	0.1375	[0.079-0.196] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.303969989	NA	0.1375
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	15q15.3	15	43703591	chr15mb43	STRCP1	NA	NA	ENSG00000166763	NA	NA	rs2470135-T	rs2470135	0	2470135	non_coding_transcript_exon_variant	FALSE	0.281498346	2e-6	5.698970004336019	NA	0.1437	[0.084-0.203] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.281498346	NA	0.1437
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	15q15.1	15	41614210	chr15mb41	TYRO3 - MGA	ENSG00000092445	ENSG00000174197	NA	30621	6924	rs28830936-A	rs28830936	0	28830936	intron_variant	TRUE	0.346714626	4e-7	6.3979400086720375	NA	0.1465	[0.09-0.203] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.346714626	NA	0.1465
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6p21.32	6	33148887	HLA	HCG24 - COL11A2	ENSG00000233043	ENSG00000235708	NA	1120	13794	rs538617339-?	rs538617339	1	3066405	regulatory_region_variant	TRUE	0.663141494	2e-7	6.698970004336019	NA	0.153	[0.095-0.211] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.663141494	NA	0.153
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q14.1	2	113638251	chr2mb114	RABL2A	NA	NA	ENSG00000144134	NA	NA	rs4849254-T	rs4849254	0	4849254	intron_variant	FALSE	0.348406113	4e-6	5.3979400086720375	NA	0.1581	[0.091-0.225] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.348406113	NA	0.1581
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6p22.2	6	26341073	HLA	H3C9P - BTN3A2	ENSG00000220875	ENSG00000186470	NA	18781	24086	rs9467715-C	rs9467715	0	9467715	regulatory_region_variant	TRUE	0.266709019	5e-7	6.301029995663981	NA	0.1613	[0.099-0.224] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.266709019	NA	0.1613
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	8q21.13	8	81818922	chr8mb82	SNX16	NA	NA	ENSG00000104497	NA	NA	rs7833790-C	rs7833790	0	7833790	intron_variant	FALSE	0.746799449	2e-7	6.698970004336019	NA	0.162	[0.1-0.22] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.746799449	NA	0.162
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	13q13.3	13	37646024	chr13mb38	TRPC4	NA	NA	ENSG00000133107	NA	NA	rs9547996-G	rs9547996	0	9547996	intron_variant	FALSE	0.247278574	2e-7	6.698970004336019	NA	0.164	[0.1-0.23] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.247278574	NA	0.164
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6p21.32	6	32835030	HLA	TAP2, TAP2, TAP2, TAP2, TAP2, TAP2, TAP2, TAP2	NA	NA	ENSG00000237599, ENSG00000204267, ENSG00000232326, ENSG00000225967, ENSG00000228582, ENSG00000206235, ENSG00000206299, ENSG00000223481	NA	NA	rs4148872-T	rs4148872	0	4148872	intron_variant	FALSE	0.148057452	2e-7	6.698970004336019	NA	0.2012	[0.13-0.28] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.148057452	NA	0.2012
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	10q25.3	10	114037712	ADRB1	NA - ADRB1	NA	ENSG00000043591	NA	NA	6154	rs17875419-?	rs17875419	0	17875419	intergenic_variant	TRUE	0.129832981	5e-7	6.301029995663981	NA	0.2099	[0.13-0.29] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.129832981	NA	0.2099
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	20p12.2	20	10746012	JAG1	LINC01752	NA	NA	ENSG00000224961	NA	NA	rs80139154-C	rs80139154	0	80139154	intron_variant	FALSE	0.073490382	8e-8	7.096910013008056	NA	0.2957	[0.19-0.4] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.073490382	NA	0.2957
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	3q21.1	3	122398816	chr3mb122	FAM162A	NA	NA	ENSG00000114023	NA	NA	rs9834975-T	rs9834975	0	9834975	intron_variant	FALSE	0.441389248	1e-8	8	NA	0.1548	[0.1-0.21] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.441389248	NA	0.1548
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6q23.3	6	135193692	chr6mb135	MYB	NA	NA	ENSG00000118513	NA	NA	rs34931156-?	rs34931156	0	34931156	intron_variant	FALSE	0.20929338	9e-6	5.045757490560675	NA	0.1575	[0.088-0.227] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.20929338	NA	0.1575
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2p21	2	45651621	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs687914-T	rs687914	0	687914	5_prime_UTR_variant	FALSE	0.251815207	4e-7	6.3979400086720375	NA	0.1622	[0.099-0.225] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.251815207	NA	0.1622
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	13q34	13	110307296	chr13mb110	COL4A2	NA	NA	ENSG00000134871	NA	NA	rs7989823-C	rs7989823	0	7989823	5_prime_UTR_variant	FALSE	0.565985719	3e-7	6.522878745280337	NA	0.1654	[0.1-0.23] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.565985719	NA	0.1654
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6p21.33	6	31601927	HLA	NCR3 - UQCRHP1	ENSG00000237808	ENSG00000229189	NA	8921	9156	rs2507960-A	rs2507960	0	2507960	intergenic_variant	TRUE	0.139916952	3e-6	5.522878745280337	NA	0.1878	[0.11-0.27] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.139916952	NA	0.1878
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17p13.1	17	7281743	TP53, SLC2A4	SLC2A4	NA	NA	ENSG00000181856	NA	NA	rs5417-A	rs5417	0	5417	5_prime_UTR_variant	FALSE	0.57	1e-13	13	NA	0.207	[0.15-0.27] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.57	NA	0.207
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	5q33.3	5	159021393	EBF1	EBF1	NA	NA	ENSG00000164330	NA	NA	rs888987-C	rs888987	0	888987	intron_variant	FALSE	0.37	4e-8	7.3979400086720375	NA	0.16	[0.1-0.22] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.37	NA	0.16
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	12p12.2	12	20215335	PDE3A	LINC02468 - PDE3A	ENSG00000256499	ENSG00000172572	NA	79172	153202	rs60691990-T	rs60691990	0	60691990	intergenic_variant	TRUE	0.65	5e-22	21.30102999566398	NA	0.283	[0.22-0.34] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.65	NA	0.283
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	12q24.21	12	115490635	TBX5, TBX3	NA	NA	NA	NA	NA	NA	rs10850519-C	rs10850519	0	10850519	intergenic_variant	TRUE	0.3	5e-13	12.301029995663981	NA	0.214	[0.16-0.27] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.3	NA	0.214
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	20p12.2	20	10787163	JAG1	LINC01752 - NA	ENSG00000224961	NA	NA	33130	NA	rs1040922-T	rs1040922	0	1040922	intron_variant	TRUE	0.28	4e-16	15.397940008672037	NA	0.245	[0.19-0.3] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.28	NA	0.245
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	20q13.13	20	48794612	PREX1	PREX1	NA	NA	ENSG00000124126	NA	NA	rs80346118-A	rs80346118	0	80346118	intron_variant	FALSE	0.15	1e-12	12	NA	0.273	[0.19-0.35] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.15	NA	0.273
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	21q22.3	21	43301010	CRYAA, SIK1	NA - LINC00322	NA	ENSG00000237864	NA	NA	21407	rs79094191-T	rs79094191	0	79094191	intergenic_variant	TRUE	0.96	4e-13	12.397940008672037	NA	0.564	[0.41-0.72] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.96	NA	0.564
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (terbinafine)	14 European ancestry cases, 10,588 European ancestry controls.	NA	NA	NA	NA	MHC	NA	NA	NA	NA	NA	NA	A*33:01-B*14:02-C*08:02-?	A*33:01-B*14:02-C*08:02	0	NA	NA	TRUE	0.009	1e-10	10	NA	49.2	NA	Illumina [505740] (imputed)	N	drug-induced liver injury, response to terbinafine	http://www.ebi.ac.uk/efo/EFO_0004228, http://www.ebi.ac.uk/efo/EFO_0007923	GCST004078	Genome-wide genotyping array	0.009	49.2	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced hepatocellular liver injury	474 European ancestry cases, 10,588 European ancestry controls	NA	4q31.3	4	150759175	LRBA	LRBA	NA	NA	ENSG00000198589	NA	NA	rs28521457-?	rs28521457	0	28521457	intron_variant	FALSE	0.040	5e-9	8.301029995663981	NA	2.1	1.6-2.7	Illumina [505740] (imputed)	N	drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0004228	GCST004079	Genome-wide genotyping array	0.04	2.1	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (statins)	59 European ancestry cases, 10,588 European ancestry controls	NA	18q22.1	18	66962261	intergenic	RNU6-1037P - NA	ENSG00000238680	NA	NA	16039	NA	rs116561224-?	rs116561224	0	116561224	intergenic_variant	TRUE	0.09	7e-9	8.154901959985743	NA	5.4	3.0-9.5	Illumina [505740] (imputed)	N	response to statin, drug-induced liver injury	http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004080	Genome-wide genotyping array	0.09	5.4	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced cholestatic/mixed liver injury	323 European ancestry cases, 10,588 European ancestry controls.	NA	2p25.2	2	5092045	NR	NA	NA	NA	NA	NA	NA	rs72631567-?	rs72631567	0	72631567	intergenic_variant	TRUE	0.03	1e-6	6	NA	2.4	1.7-3.4	Illumina [505740] (imputed)	N	drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0004228	GCST004081	Genome-wide genotyping array	0.03	2.4	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced cholestatic/mixed liver injury	323 European ancestry cases, 10,588 European ancestry controls.	NA	NA	NA	NA	MHC	NA	NA	NA	NA	NA	NA	A*33:01-?	A*33:01	0	NA	NA	TRUE	0.01	4e-13	12.397940008672037	NA	5	3.3-7.9	Illumina [505740] (imputed)	N	drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0004228	GCST004081	Genome-wide genotyping array	0.01	5	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced cholestatic/mixed liver injury	323 European ancestry cases, 10,588 European ancestry controls.	NA	NA	NA	NA	MHC	NA	NA	NA	NA	NA	NA	A*33:01-B*14:02-C*08:02-?	A*33:01-B*14:02-C*08:02	0	NA	NA	TRUE	0.009	4e-13	12.397940008672037	NA	5.7	NA	Illumina [505740] (imputed)	N	drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0004228	GCST004081	Genome-wide genotyping array	0.009	5.7	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (nitrofurantoin)	64 European ancestry cases, 10,588 European ancestry controls	NA	14q31.3	14	88105563	NA	LINC01146 - KCNK10	ENSG00000258867	ENSG00000100433	NA	7538	74540	rs72696020-?	rs72696020	0	72696020	intergenic_variant	TRUE	NA	6e-8	7.221848749616356	NA	7.8	3.52-14.66	Illumina [505740] (imputed)	N	response to nitrofurantoin, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007921, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004082	Genome-wide genotyping array	NA	7.8	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (nitrofurantoin)	64 European ancestry cases, 10,588 European ancestry controls	NA	1p36.13	1	18793883	NA	PAX7 - TAS1R2	ENSG00000009709	ENSG00000179002	NA	45017	45716	rs6694270-?	rs6694270	0	6694270	regulatory_region_variant	TRUE	NA	2e-7	6.698970004336019	NA	2.59	1.81-3.71	Illumina [505740] (imputed)	N	response to nitrofurantoin, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007921, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004082	Genome-wide genotyping array	NA	2.59	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (nitrofurantoin)	64 European ancestry cases, 10,588 European ancestry controls	NA	19q13.33	19	50657831	NA	C19orf81	NA	NA	ENSG00000235034	NA	NA	rs10404821-?	rs10404821	0	10404821	intron_variant	FALSE	NA	2e-7	6.698970004336019	NA	2.56	1.80-3.65	Illumina [505740] (imputed)	N	response to nitrofurantoin, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007921, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004082	Genome-wide genotyping array	NA	2.56	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (nitrofurantoin)	64 European ancestry cases, 10,588 European ancestry controls	NA	10q21.3	10	65095495	NA	NEK4P3 - MYL6P3	ENSG00000270754	ENSG00000227173	NA	40492	73943	rs61858823-?	rs61858823	0	61858823	intergenic_variant	TRUE	NA	5e-7	6.301029995663981	NA	5.63	2.88-11.02	Illumina [505740] (imputed)	N	response to nitrofurantoin, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007921, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004082	Genome-wide genotyping array	NA	5.63	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (diclofenac)	67 European ancestry cases, 10,588 European ancestry controls	NA	5q34	5	161257724	NR	NA - GABRB2	NA	ENSG00000145864	NA	NA	30705	rs114811931-?	rs114811931	0	114811931	intergenic_variant	TRUE	NR	3e-9	8.522878745280337	NA	6.59	3.54-12.28	Illumina [505740] (imputed)	N	response to diclofenac, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007919, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004083	Genome-wide genotyping array	NA	6.59	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (diclofenac)	67 European ancestry cases, 10,588 European ancestry controls	NA	10q23.33	10	92818147	NA	NA - EXOC6	NA	ENSG00000138190	NA	NA	8684	rs113206698-?	rs113206698	0	113206698	intergenic_variant	TRUE	NR	6e-7	6.221848749616356	NA	3.79	2.25-6.39	Illumina [505740] (imputed)	N	response to diclofenac, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007919, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004083	Genome-wide genotyping array	NA	3.79	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (diclofenac)	67 European ancestry cases, 10,588 European ancestry controls	NA	3p26.3	3	779530	NR	LINC01266	NA	NA	ENSG00000224957	NA	NA	rs115266745-?	rs115266745	0	115266745	intron_variant	FALSE	NA	7e-7	6.154901959985743	NA	6.8	3.19-14.48	Illumina [505740] (imputed)	N	response to diclofenac, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007919, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004083	Genome-wide genotyping array	NA	6.8	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (diclofenac)	67 European ancestry cases, 10,588 European ancestry controls	NA	5q23.1	5	121540642	NR	NA - RPL23AP44	NA	ENSG00000244088	NA	NA	35206	rs149014830-?	rs149014830	0	149014830	intergenic_variant	TRUE	NR	7e-7	6.154901959985743	NA	6.04	2.96-12.3	Illumina [505740] (imputed)	N	response to diclofenac, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007919, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004083	Genome-wide genotyping array	NA	6.04	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (anti-tuberculosis drugs)	67 European ancestry cases, 10,588 European ancestry controls	NA	9q33.1	9	116881377	NA	ASTN2	NA	NA	ENSG00000148219	NA	NA	rs117491755-?	rs117491755	0	117491755	intron_variant	FALSE	NA	1e-7	7	NA	3.92	2.35-6.51	Illumina [505740] (imputed)	N	response to anti-tuberculosis drug, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007918, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004084	Genome-wide genotyping array	NA	3.92	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (anti-tuberculosis drugs)	67 European ancestry cases, 10,588 European ancestry controls	NA	9p23	9	9593742	NA	PTPRD	NA	NA	ENSG00000153707	NA	NA	rs143575776-?	rs143575776	0	143575776	intron_variant	FALSE	NA	2e-7	6.698970004336019	NA	4.96	2.70-9.09	Illumina [505740] (imputed)	N	response to anti-tuberculosis drug, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007918, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004084	Genome-wide genotyping array	NA	4.96	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (anti-tuberculosis drugs)	67 European ancestry cases, 10,588 European ancestry controls	NA	3p12.3	3	79310483	NR	ROBO1	NA	NA	ENSG00000169855	NA	NA	rs73122578-?	rs73122578	0	73122578	intron_variant	FALSE	NR	5e-7	6.301029995663981	NA	2.42	1.71-3.40	Illumina [505740] (imputed)	N	response to anti-tuberculosis drug, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007918, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004084	Genome-wide genotyping array	NA	2.42	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (fluoroquinolones)	43 European ancestry cases, 10,588 European ancestry controls	NA	2p16.1	2	56422795	NA	CCDC85A - NA	ENSG00000055813	NA	NA	36623	NA	rs186920977-?	rs186920977	0	186920977	intergenic_variant	TRUE	NA	1e-7	7	NA	7.22	3.47-15.01	Illumina [505740] (imputed)	N	response to fluoroquinolones, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007920, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004085	Genome-wide genotyping array	NA	7.22	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (fluoroquinolones)	43 European ancestry cases, 10,588 European ancestry controls	NA	3q21.1	3	123918335	NA	CCDC14	NA	NA	ENSG00000175455	NA	NA	rs191153876-?	rs191153876	0	191153876	intron_variant	FALSE	NA	2e-7	6.698970004336019	NA	7.33	3.46-15.5	Illumina [505740] (imputed)	N	response to fluoroquinolones, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007920, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004085	Genome-wide genotyping array	NA	7.33	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (fluoroquinolones)	43 European ancestry cases, 10,588 European ancestry controls	NA	5p14.1	5	28665845	NA	RNU6-909P - NA	ENSG00000252867	NA	NA	41082	NA	rs116606120-?	rs116606120	0	116606120	intron_variant	TRUE	NA	3e-7	6.522878745280337	NA	8.6	3.79-19.5	Illumina [505740] (imputed)	N	response to fluoroquinolones, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007920, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004085	Genome-wide genotyping array	NA	8.6	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (fluoroquinolones)	43 European ancestry cases, 10,588 European ancestry controls	NA	18p11.22	18	9841518	NA	RAB31	NA	NA	ENSG00000168461	NA	NA	rs112655218-?	rs112655218	0	112655218	non_coding_transcript_exon_variant	FALSE	NA	3e-7	6.522878745280337	NA	4.54	NA	Illumina [505740] (imputed)	N	response to fluoroquinolones, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007920, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004085	Genome-wide genotyping array	NA	4.54	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (nonsteroidal anti-inflammatory drugs)	144 European ancestry cases, 10,588 European ancestry controls	NA	7q34	7	140018347	NA	TBXAS1	NA	NA	ENSG00000059377	NA	NA	rs2240395-?	rs2240395	0	2240395	intron_variant	FALSE	NA	3e-7	6.522878745280337	NA	1.84	1.45-2.31	Illumina [505740] (imputed)	N	response to non-steroidal anti-inflammatory, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0005533, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004087	Genome-wide genotyping array	NA	1.84	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (nonsteroidal anti-inflammatory drugs)	144 European ancestry cases, 10,588 European ancestry controls	NA	1p36.31	1	6845651	NA	CAMTA1	NA	NA	ENSG00000171735	NA	NA	rs185305928-?	rs185305928	0	185305928	intron_variant	FALSE	NA	3e-7	6.522878745280337	NA	4.55	2.55-8.11	Illumina [505740] (imputed)	N	response to non-steroidal anti-inflammatory, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0005533, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004087	Genome-wide genotyping array	NA	4.55	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (nonsteroidal anti-inflammatory drugs)	144 European ancestry cases, 10,588 European ancestry controls	NA	11q14.1	11	85725825	NA	SYTL2	NA	NA	ENSG00000137501	NA	NA	rs597480-?	rs597480	0	597480	missense_variant	FALSE	NA	4e-7	6.3979400086720375	NA	1.84	1.45-2.32	Illumina [505740] (imputed)	N	response to non-steroidal anti-inflammatory, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0005533, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004087	Genome-wide genotyping array	NA	1.84	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury (nonsteroidal anti-inflammatory drugs)	144 European ancestry cases, 10,588 European ancestry controls	NA	14q24.1	14	68376888	NA	RAD51B	NA	NA	ENSG00000182185	NA	NA	rs2025009-?	rs2025009	0	2025009	intron_variant	FALSE	NA	7e-7	6.154901959985743	NA	1.81	1.43-2.29	Illumina [505740] (imputed)	N	response to non-steroidal anti-inflammatory, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0005533, http://www.ebi.ac.uk/efo/EFO_0004228	GCST004087	Genome-wide genotyping array	NA	1.81	NA
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1p13.2	1	115286557	chr1mb115	NGF, NGF-AS1	NA	NA	ENSG00000134259, ENSG00000228035	NA	NA	rs11466111-T	rs11466111	0	11466111	missense_variant	FALSE	0.017550148	5e-10	9.301029995663981	NA	0.6488	[0.44-0.85] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.017550148	NA	0.6488
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	14q13.3	14	36401137	chr14mb36	DPPA3P2 - RNU7-93P	ENSG00000188831	ENSG00000238540	NA	28754	4077	rs117059939-T	rs117059939	0	117059939	intron_variant	TRUE	0.013699408	3e-7	6.522878745280337	NA	0.7517	[0.46-1.04] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.013699408	NA	0.7517
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	15q23	15	69390577	chr15mb69	PAQR5	NA	NA	ENSG00000137819	NA	NA	rs117539635-G	rs117539635	0	117539635	intron_variant	FALSE	0.025173323	2e-8	7.698970004336019	NA	0.6472	[0.42-0.87] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.025173323	NA	0.6472
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	5q14.3	5	92585251	chr5mb91	NA	NA	NA	NA	NA	NA	rs181808701-T	rs181808701	0	181808701	intron_variant	TRUE	0.025296063	1e-7	7	NA	0.5134	[0.32-0.7] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.025296063	NA	0.5134
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	8p23.1	8	6494184	chr8mb6	MCPH1	NA	NA	ENSG00000147316	NA	NA	rs141416541-T	rs141416541	0	141416541	non_coding_transcript_exon_variant	FALSE	0.03375072	4e-7	6.3979400086720375	NA	0.4511	[0.28-0.63] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.03375072	NA	0.4511
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6p21.32	6	32590651	HLA	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735	NA	803	37528	rs184318723-C	rs184318723	0	184318723	intron_variant	TRUE	0.044778943	3e-6	5.522878745280337	NA	0.4466	[0.26-0.63] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.044778943	NA	0.4466
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	8q24.3	8	143820544	chr8mb144	PUF60	NA	NA	ENSG00000179950	NA	NA	rs4076877-T	rs4076877	0	4076877	non_coding_transcript_exon_variant	FALSE	0.049077341	4e-8	7.3979400086720375	NA	0.4184	[0.27-0.57] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.049077341	NA	0.4184
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	11q22.1	11	100648287	FLJ32810, TMEM133	RN7SL222P - PPIAP43	ENSG00000242165	ENSG00000255059	NA	6014	18172	rs71476638-A	rs71476638	0	71476638	intergenic_variant	TRUE	0.053673691	7e-8	7.154901959985743	NA	0.3665	[0.23-0.5] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.053673691	NA	0.3665
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q35	2	218789537	chr2mb219	CYP27A1	NA	NA	ENSG00000135929	NA	NA	rs1816213-T	rs1816213	0	1816213	intron_variant	FALSE	0.052114145	2e-7	6.698970004336019	NA	0.3218	[0.2-0.44] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.052114145	NA	0.3218
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q22.3	2	145181135	TEX41	TEX41	NA	NA	ENSG00000226674	NA	NA	rs62167177-T	rs62167177	0	62167177	intron_variant	FALSE	0.138856916	1e-9	9	NA	0.2592	[0.18-0.34] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.138856916	NA	0.2592
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17q23.2	17	62923972	MRC2	PRELID3BP3 - MIR633	ENSG00000264907	ENSG00000207552	NA	82327	20243	rs56174355-T	rs56174355	0	56174355	intron_variant	TRUE	0.078555103	1e-7	7	NA	0.2543	[0.16-0.35] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.078555103	NA	0.2543
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	21q22.3	21	43586730	RRP1B	HSF2BP	NA	NA	ENSG00000160207	NA	NA	rs35123175-?	rs35123175	0	35123175	intron_variant	FALSE	0.095811672	2e-7	6.698970004336019	NA	0.2452	[0.15-0.34] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.095811672	NA	0.2452
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	12q24.21	12	115490635	TBX5, TBX3	NA	NA	NA	NA	NA	NA	rs10850519-C	rs10850519	0	10850519	intergenic_variant	TRUE	0.3	5e-13	12.301029995663981	NA	0.214	[0.16-0.27] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.3	NA	0.214
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	15q26.2	15	96092669	chr15mb96	RNU2-3P - NR2F2-AS1	ENSG00000222076	ENSG00000247809	NA	346675	17371	rs4984496-G	rs4984496	0	4984496	intron_variant	TRUE	0.67238753	3e-9	8.522878745280337	NA	0.1759	[0.12-0.23] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.67238753	NA	0.1759
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	11q24.3	11	128892289	chr11mb128	KCNJ5	NA	NA	ENSG00000120457	NA	NA	rs66518071-G	rs66518071	0	66518071	intron_variant	FALSE	0.253060221	2e-6	5.698970004336019	NA	0.1682	[0.099-0.238] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.253060221	NA	0.1682
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	5q13.3	5	75742606	POC5	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078	NA	25158	9964	rs10078021-T	rs10078021	0	10078021	intergenic_variant	TRUE	0.63	1e-8	8	NA	0.164	[0.11-0.22] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.63	NA	0.164
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	3q21.3	3	127499961	chr3mb127	LINC01471	NA	NA	ENSG00000239921	NA	NA	rs17282160-T	rs17282160	0	17282160	intron_variant	FALSE	0.219140983	5e-6	5.301029995663981	NA	0.1578	[0.09-0.225] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.219140983	NA	0.1578
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	7p14.2	7	35435712	chr7mb35	NA	NA	NA	NA	NA	NA	rs2541918-T	rs2541918	0	2541918	intergenic_variant	TRUE	0.680063457	8e-7	6.096910013008056	NA	0.1567	[0.095-0.219] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.680063457	NA	0.1567
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6q22.1	6	117493004	chr6mb117	DCBLD1	NA	NA	ENSG00000164465	NA	NA	rs2018055-C	rs2018055	0	2018055	intron_variant	FALSE	0.239089735	8e-7	6.096910013008056	NA	0.1557	[0.094-0.217] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.239089735	NA	0.1557
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	3p25.1	3	14918317	FGD5	FGD5	NA	NA	ENSG00000154783	NA	NA	rs13099220-T	rs13099220	0	13099220	intron_variant	FALSE	0.218188697	5e-6	5.301029995663981	NA	0.1505	[0.086-0.215] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.218188697	NA	0.1505
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	19p12	19	21696775	chr19mb21	MTDHP3 - MTDHP4	ENSG00000268433	ENSG00000280066	NA	18554	12747	rs11671323-G	rs11671323	0	11671323	intergenic_variant	TRUE	0.417849335	3e-7	6.522878745280337	NA	0.149	[0.092-0.206] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.417849335	NA	0.149
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	13q34	13	113801051	chr13mb114	TMEM255B	NA	NA	ENSG00000184497	NA	NA	rs3934941-G	rs3934941	0	3934941	intron_variant	FALSE	0.462898738	4e-6	5.3979400086720375	NA	0.1434	[0.083-0.204] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.462898738	NA	0.1434
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	7p14.2	7	35198920	chr7mb35	DPY19L2P1 - TBX20	ENSG00000189212	ENSG00000164532	NA	12879	3510	rs3206736-T	rs3206736	0	3206736	regulatory_region_variant	TRUE	0.475462799	6e-6	5.221848749616356	NA	0.1301	[0.074-0.187] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.475462799	NA	0.1301
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q22.3	2	145408953	TEX41	RPL6P5 - NA	ENSG00000214064	NA	NA	70896	NA	rs12996225-C	rs12996225	0	12996225	intergenic_variant	TRUE	0.513828239	4e-6	5.3979400086720375	NA	0.1254	[0.072-0.179] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.513828239	NA	0.1254
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1q25.1	1	175161068	chr1mb175	KIAA0040	NA	NA	ENSG00000235750	NA	NA	rs1057239-A	rs1057239	0	1057239	5_prime_UTR_variant	FALSE	0.468363595	4e-6	5.3979400086720375	NA	0.1253	[0.072-0.178] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.468363595	NA	0.1253
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	16p13.3	16	4893018	PPL	PPL	NA	NA	ENSG00000118898	NA	NA	rs12921187-T	rs12921187	0	12921187	non_coding_transcript_exon_variant	FALSE	0.43	3e-10	9.522878745280337	NA	0.174	[0.12-0.23] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.43	NA	0.174
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	16q23.2	16	81540592	CMIP	CMIP	NA	NA	ENSG00000153815	NA	NA	rs8059962-T	rs8059962	0	8059962	intron_variant	FALSE	0.42	1e-9	9	NA	0.17	[0.11-0.23] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.42	NA	0.17
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1q24.3	1	172388301	DNM3	PIGC, DNM3	NA	NA	ENSG00000135845, ENSG00000197959	NA	NA	rs12405515-T	rs12405515	0	12405515	intron_variant	FALSE	0.56	1e-9	9	NA	0.165	[0.11-0.22] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.56	NA	0.165
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	11p14.1	11	27706555	BDNF	BDNF	NA	NA	ENSG00000176697	NA	NA	rs11030119-A	rs11030119	0	11030119	intron_variant	FALSE	0.31	3e-8	7.522878745280337	NA	0.163	[0.1-0.22] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.31	NA	0.163
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2p22.1	2	40340603	SLC8A1	SLC8A1	NA	NA	ENSG00000183023	NA	NA	rs4952611-T	rs4952611	0	4952611	intron_variant	FALSE	0.58	4e-8	7.3979400086720375	NA	0.157	[0.098-0.216] unit decrease	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.58	NA	0.157
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	3q27.2	3	185599886	SENP2	SENP2	NA	NA	ENSG00000163904	NA	NA	rs12374077-C	rs12374077	0	12374077	intron_variant	FALSE	0.35	9e-9	8.045757490560675	NA	0.163	[0.1-0.22] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.35	NA	0.163
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	8q22.3	8	100664447	SNX31	SNX31 - RNU6-1092P	ENSG00000174226	ENSG00000252764	NA	1032	19041	rs2978098-A	rs2978098	0	2978098	intergenic_variant	TRUE	0.54	2e-9	8.698970004336019	NA	0.165	[0.11-0.22] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.54	NA	0.165
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6p12.2	6	51967696	PKHD1	PKHD1	NA	NA	ENSG00000170927	NA	NA	rs13205180-T	rs13205180	0	13205180	intron_variant	FALSE	0.49	7e-10	9.154901959985743	NA	0.168	[0.11-0.23] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.49	NA	0.168
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	19q12	19	29804084	CCNE1	C19orf12 - CCNE1	ENSG00000131943	ENSG00000105173	NA	88295	7907	rs62104477-T	rs62104477	0	62104477	intergenic_variant	TRUE	0.33	1e-9	9	NA	0.177	[0.12-0.24] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.33	NA	0.177
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	16p11.2	16	30925422	FBXL19	FBXL19	NA	NA	ENSG00000099364	NA	NA	rs72799341-A	rs72799341	0	72799341	intron_variant	FALSE	0.24	6e-9	8.221848749616356	NA	0.185	[0.13-0.24] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.24	NA	0.185
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	18q21.1	18	50616484	MAPK4	MAPK4	NA	NA	ENSG00000141639	NA	NA	rs745821-T	rs745821	0	745821	intron_variant	FALSE	0.76	1e-9	9	NA	0.189	[0.13-0.25] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.76	NA	0.189
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1q41	1	217545447	GPATCH2	GPATCH2	NA	NA	ENSG00000092978	NA	NA	rs12408022-T	rs12408022	0	12408022	intron_variant	FALSE	0.26	2e-10	9.698970004336019	NA	0.198	[0.14-0.26] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.26	NA	0.198
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	17q23.3	17	63482264	ACE	ACE	NA	NA	ENSG00000159640	NA	NA	rs4308-A	rs4308	0	4308	intron_variant	FALSE	0.37	7e-14	13.154901959985743	NA	0.213	[0.15-0.27] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.37	NA	0.213
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1q43	1	243307890	SDCCAG8	SDCCAG8, SDCCAG8	NA	NA	ENSG00000054282, ENSG00000276111	NA	NA	rs953492-A	rs953492	0	953492	splice_region_variant	FALSE	0.46	7e-16	15.154901959985743	NA	0.22	[0.16-0.28] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.46	NA	0.22
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1q42.13	1	228003374	WNT3A	SEPTIN14P17 - WNT3A	ENSG00000274886	ENSG00000154342	NA	23147	3624	rs2760061-A	rs2760061	0	2760061	intergenic_variant	TRUE	0.47	2e-16	15.698970004336019	NA	0.23	[0.17-0.29] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.47	NA	0.23
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	3p21.31	3	50438947	CACNA2D2	CACNA2D2	NA	NA	ENSG00000007402	NA	NA	rs743757-C	rs743757	0	743757	intron_variant	FALSE	0.14	2e-10	9.698970004336019	NA	0.245	[0.17-0.32] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.14	NA	0.245
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2p23.3	2	24916727	ADCY3	ADCY3	NA	NA	ENSG00000138031	NA	NA	rs55701159-T	rs55701159	0	55701159	intron_variant	FALSE	0.89	7e-11	10.154901959985743	NA	0.285	[0.21-0.36] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.89	NA	0.285
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6q22.31	6	118251323	SLC35F1	SLC35F1	NA	NA	ENSG00000196376	NA	NA	rs9372498-A	rs9372498	0	9372498	intron_variant	FALSE	0.08	2e-11	10.698970004336019	NA	0.334	[0.24-0.43] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.08	NA	0.334
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	1p36.11	1	24703979	chr1mb25	SRRM1 - CLIC4	ENSG00000133226	ENSG00000169504	NA	30698	41403	rs6686889-T	rs6686889	0	6686889	intergenic_variant	TRUE	0.25	4e-9	8.397940008672037	NA	0.185	[0.13-0.24] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.25	NA	0.185
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	20q13.33	20	64051912	chr20mb62	TCEA2	NA	NA	ENSG00000171703	NA	NA	rs6062621-C	rs6062621	0	6062621	intron_variant	FALSE	0.112233004	1e-7	7	NA	0.2475	[0.16-0.34] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.112233004	NA	0.2475
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	6p22.2	6	27033276	HLA	LINC00240	NA	NA	ENSG00000224843	NA	NA	rs13191659-G	rs13191659	0	13191659	intron_variant	FALSE	0.085887551	1e-7	7	NA	0.2996	[0.19-0.41] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.085887551	NA	0.2996
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2q32.1	2	182410033	PDE1A	PDE1A	NA	NA	ENSG00000115252	NA	NA	rs144073138-G	rs144073138	0	144073138	intron_variant	FALSE	0.05965518	2e-8	7.698970004336019	NA	0.3478	[0.23-0.47] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.05965518	NA	0.3478
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	15q24.1	15	74057646	chr15mb74	PML - DNM1P33	ENSG00000140464	ENSG00000260096	NA	9819	5134	rs56007454-C	rs56007454	0	56007454	intergenic_variant	TRUE	0.030106756	7e-6	5.154901959985743	NA	0.3689	[0.21-0.53] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.030106756	NA	0.3689
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	2p21	2	42940738	AC016735.1	NA - LINC01819	NA	ENSG00000231826	NA	NA	87085	rs76326501-A	rs76326501	0	76326501	intergenic_variant	TRUE	0.91	4e-18	17.397940008672037	NA	0.419	[0.32-0.52] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.91	NA	0.419
2017-07-01	28135244	Warren HR	2017-01-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Diastolic blood pressure	140,886 European ancestry individuals	190,318 European ancestry individuals	4q21.21	4	80258836	FGF5	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675	NA	54507	7803	rs36077257-T	rs36077257	0	36077257	intergenic_variant	TRUE	0.025452528	1e-7	7	NA	0.4886	[0.31-0.67] unit increase	Affymetrix [~ 9800000] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004280	Genome-wide genotyping array	0.025452528	NA	0.4886
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p36.11	1	26936054	NUDC	NUDC	NA	NA	ENSG00000090273	NA	NA	rs182050989-T	rs182050989	0	182050989	intron_variant	FALSE	0.0292	2e-12	11.698970004336019	NA	0.07717716	[0.056-0.099] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0292	NA	0.07717716
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p35.2	1	30769039	intergenic	LAPTM5 - LINC01778	ENSG00000162511	ENSG00000223382	NA	11265	55178	rs74340846-T	rs74340846	0	74340846	intergenic_variant	TRUE	0.0105	4e-15	14.397940008672037	NA	0.1631896	[0.12-0.2] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0105	NA	0.1631896
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p34.2	1	43375311	intergenic	ELOVL1 - MED8	ENSG00000066322	ENSG00000159479	NA	7237	8606	rs75139539-T	rs75139539	0	75139539	intergenic_variant	TRUE	0.0322	2e-9	8.698970004336019	NA	0.06257873	[0.042-0.083] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0322	NA	0.06257873
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p34.1	1	45396806	TESK2	TESK2	NA	NA	ENSG00000070759	NA	NA	rs551907009-G	rs551907009	1	55739766	intron_variant	FALSE	0.3232	2e-15	14.698970004336019	NA	0.03171634	[0.024-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3232	NA	0.03171634
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p22.3	1	87639807	intergenic	PKN2-AS1	NA	NA	ENSG00000237505	NA	NA	rs151136305-A	rs151136305	0	151136305	intron_variant	FALSE	0.0568	3e-11	10.522878745280337	NA	0.05271428	[0.037-0.068] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0568	NA	0.05271428
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p13.2	1	112614239	ST7L	ST7L	NA	NA	ENSG00000007341	NA	NA	rs112416932-AAAAC	rs112416932	1	61698183	intron_variant	FALSE	0.4645	5e-12	11.301029995663981	NA	0.02553016	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4645	NA	0.02553016
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1q21.2	1	150355421	PRPF3	PRPF3 - RPRD2	ENSG00000117360	ENSG00000163125	NA	2188	7670	rs370869951-CA	rs370869951	0	370869951	intergenic_variant	TRUE	0.378	3e-10	9.522878745280337	NA	0.02394158	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.378	NA	0.02394158
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1q22	1	156464911	MEF2D	MEF2D	NA	NA	ENSG00000116604	NA	NA	rs1050316-T	rs1050316	0	1050316	3_prime_UTR_variant	FALSE	0.6515	2e-14	13.698970004336019	NA	0.0295196	[0.022-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6515	NA	0.0295196
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1q23.1	1	156718360	ISG20L2	CRABP2 - ISG20L2	ENSG00000143320	ENSG00000143319	NA	12544	3531	rs11264531-T	rs11264531	0	11264531	intergenic_variant	TRUE	0.3592	3e-13	12.522878745280337	NA	0.02827919	[0.021-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3592	NA	0.02827919
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1q32.1	1	199025568	RP11-16L9.4	LINC01221	NA	NA	ENSG00000235492	NA	NA	rs781255974-T	rs781255974	1	35481188	intron_variant	FALSE	0.7247	2e-36	35.69897000433602	NA	0.05183133	[0.044-0.06] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7247	NA	0.05183133
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1q32.1	1	204311492	PLEKHA6	PLEKHA6	NA	NA	ENSG00000143850	NA	NA	rs36122125-CA	rs36122125	0	36122125	intron_variant	FALSE	0.2426	2e-12	11.698970004336019	NA	0.03067111	[0.022-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2426	NA	0.03067111
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1q42.12	1	225774988	SRP9	RNU6-1304P - SRP9	ENSG00000223306	ENSG00000143742	NA	33608	2825	rs6696074-T	rs6696074	0	6696074	intergenic_variant	TRUE	0.5651	2e-9	8.698970004336019	NA	0.02240976	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5651	NA	0.02240976
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1q44	1	247549001	GCSAML	GCSAML	NA	NA	ENSG00000169224	NA	NA	rs41315846-C	rs41315846	0	41315846	intron_variant	FALSE	0.4763	9e-23	22.045757490560675	NA	0.03646343	[0.029-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4763	NA	0.03646343
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1q44	1	247556467	GCSAML	GCSAML	NA	NA	ENSG00000169224	NA	NA	rs56043070-A	rs56043070	0	56043070	splice_donor_variant	FALSE	0.0712	4e-43	42.39794000867204	NA	0.09746174	[0.084-0.111] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0712	NA	0.09746174
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2p24.1	2	23677078	KLHL29	KLHL29	NA	NA	ENSG00000119771	NA	NA	rs6714016-G	rs6714016	0	6714016	intron_variant	FALSE	0.183	7e-11	10.154901959985743	NA	0.03070206	[0.021-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.183	NA	0.03070206
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2p23.3	2	27508073	GCKR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs1260326-C	rs1260326	0	1260326	missense_variant	FALSE	0.6049	1e-21	21	NA	0.03560478	[0.028-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6049	NA	0.03560478
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2p23.1	2	31254972	EHD3	EHD3	NA	NA	ENSG00000013016	NA	NA	rs655029-A	rs655029	0	655029	intron_variant	FALSE	0.7118	1e-18	18	NA	0.0360763	[0.028-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7118	NA	0.0360763
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2p21	2	43237679	THADA	THADA	NA	NA	ENSG00000115970	NA	NA	rs113542380-A	rs113542380	0	113542380	intron_variant	FALSE	0.076	6e-32	31.221848749616356	NA	0.08249128	[0.069-0.096] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.076	NA	0.08249128
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2p14	2	68388414	PLEK	PLEK	NA	NA	ENSG00000115956	NA	NA	rs34338164-C	rs34338164	0	34338164	missense_variant	FALSE	0.009	2e-14	13.698970004336019	NA	0.15026	[0.11-0.19] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.009	NA	0.15026
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2p13.3	2	68735005	ARHGAP25	ARHGAP25	NA	NA	ENSG00000163219	NA	NA	rs10048745-A	rs10048745	0	10048745	5_prime_UTR_variant	FALSE	0.2596	5e-21	20.30102999566398	NA	0.04020253	[0.032-0.049] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2596	NA	0.04020253
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q11.2	2	100145754	AFF3	AFF3	NA	NA	ENSG00000144218	NA	NA	rs368755101-A	rs368755101	0	368755101	intron_variant	FALSE	0.3613	6e-10	9.221848749616356	NA	0.02357079	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3613	NA	0.02357079
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q13	2	111428267	MIR4435-1HG	MIR4435-2HG	NA	NA	ENSG00000172965	NA	NA	rs4377346-C	rs4377346	0	4377346	intron_variant	FALSE	0.2528	4e-19	18.397940008672037	NA	0.04127506	[0.032-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2528	NA	0.04127506
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q14.2	2	120061229	EPB41L5	EPB41L5	NA	NA	ENSG00000115109	NA	NA	rs558199115-AT	rs558199115	0	558199115	intron_variant	FALSE	0.2126	1e-9	9	NA	0.02753467	[0.019-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2126	NA	0.02753467
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q24.2	2	159827013	LY75-CD302, LY75	LY75-CD302, LY75	NA	NA	ENSG00000248672, ENSG00000054219	NA	NA	rs2955982-A	rs2955982	0	2955982	intron_variant	FALSE	0.8314	2e-22	21.69897000433602	NA	0.04763552	[0.038-0.057] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.8314	NA	0.04763552
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	2q24.2	2	159834145	LY75-CD302, LY75	LY75, LY75-CD302	NA	NA	ENSG00000054219, ENSG00000248672	NA	NA	rs78446341-A	rs78446341	0	78446341	missense_variant	FALSE	0.0234	4e-29	28.397940008672037	NA	0.1351774	[0.11-0.16] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0234	NA	0.1351774
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	8q24.12	8	118927620	TNFRSF11B	TNFRSF11B	NA	NA	ENSG00000164761	NA	NA	rs7834745-G	rs7834745	0	7834745	intron_variant	FALSE	0.1898	9e-10	9.045757490560675	NA	0.02803351	[0.019-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.1898	NA	0.02803351
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	8q24.21	8	127992729	PVT1	PVT1	NA	NA	ENSG00000249859	NA	NA	rs11786130-A	rs11786130	0	11786130	intron_variant	FALSE	0.3453	7e-21	20.154901959985743	NA	0.03517638	[0.028-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.3453	NA	0.03517638
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	8q24.21	8	129592027	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs11327184-A	rs11327184	0	11327184	intron_variant	FALSE	0.3181	9e-32	31.045757490560675	NA	0.04520017	[0.038-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.3181	NA	0.04520017
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9q34.3	9	136462535	SEC16A	SEC16A	NA	NA	ENSG00000148396	NA	NA	rs57994353-C	rs57994353	0	57994353	intron_variant	FALSE	0.2994	3e-9	8.522878745280337	NA	0.02311792	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.2994	NA	0.02311792
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9p24.1	9	4793798	RCL1	RCL1	NA	NA	ENSG00000120158	NA	NA	rs296847-T	rs296847	0	296847	intron_variant	FALSE	0.662	5e-9	8.301029995663981	NA	0.02221495	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.662	NA	0.02221495
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9p24.1	9	5075628	JAK2	JAK2	NA	NA	ENSG00000096968	NA	NA	rs10283564-G	rs10283564	0	10283564	intron_variant	FALSE	0.2514	4e-16	15.397940008672037	NA	0.03342383	[0.025-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.2514	NA	0.03342383
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9p24.1	9	6193455	RP11-575C20.1	NA - GTF3AP1	NA	ENSG00000237274	NA	NA	2479	rs2381416-A	rs2381416	0	2381416	intergenic_variant	TRUE	0.737	2e-114	113.69897000433602	NA	0.09179707	[0.084-0.1] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.737	NA	0.09179707
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9p24.1	9	6263444	intergenic	IL33 - SELENOTP1	ENSG00000137033	ENSG00000233846	NA	5461	15223	rs370820588-C	rs370820588	0	370820588	intergenic_variant	TRUE	0.0048	3e-26	25.522878745280337	NA	0.280968	[0.23-0.33] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0048	NA	0.280968
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	NA	NA	NA	RP11-307L3.2	NA	NA	NA	NA	NA	NA	chr9:6282511-A	chr9:6282511	0	NA	NA	TRUE	0.0352	5e-43	42.30102999566398	NA	0.1327941	[0.11-0.15] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0352	NA	0.1327941
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9q22.31	9	91334470	AUH	AUH	NA	NA	ENSG00000148090	NA	NA	rs201272561-T	rs201272561	0	201272561	intron_variant	FALSE	0.1578	1e-14	14	NA	0.0392951	[0.029-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.1578	NA	0.0392951
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9q31.3	9	110877852	LPAR1	LPAR1	NA	NA	ENSG00000198121	NA	NA	rs547116-A	rs547116	0	547116	intron_variant	FALSE	0.3817	6e-20	19.221848749616356	NA	0.03348749	[0.026-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.3817	NA	0.03348749
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9q33.1	9	114934056	TNFSF8	DELEC1	NA	NA	ENSG00000173077	NA	NA	rs726657-T	rs726657	0	726657	intron_variant	FALSE	0.4071	3e-11	10.522878745280337	NA	0.02429508	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.4071	NA	0.02429508
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9q34.13	9	132982259	GFI1B	GFI1B	NA	NA	ENSG00000165702	NA	NA	rs117868203-T	rs117868203	0	117868203	intron_variant	FALSE	0.017	4e-11	10.397940008672037	NA	0.1015093	[0.071-0.132] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.017	NA	0.1015093
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9q34.13	9	132989126	GFI1B	GFI1B	NA	NA	ENSG00000165702	NA	NA	rs150813342-T	rs150813342	0	150813342	synonymous_variant	FALSE	0.0085	6e-22	21.221848749616356	NA	0.1942417	[0.15-0.23] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0085	NA	0.1942417
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9q34.13	9	133001720	intergenic	GFI1B - EEF1A1P5	ENSG00000165702	ENSG00000196205	NA	10033	17766	rs34149660-C	rs34149660	0	34149660	regulatory_region_variant	TRUE	0.1135	4e-13	12.397940008672037	NA	0.04271211	[0.031-0.054] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.1135	NA	0.04271211
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9q34.13	9	133005082	intergenic	GFI1B - EEF1A1P5	ENSG00000165702	ENSG00000196205	NA	13395	14404	rs605642-A	rs605642	0	605642	regulatory_region_variant	TRUE	0.5804	2e-13	12.698970004336019	NA	0.02687869	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.5804	NA	0.02687869
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	9q34.2	9	134037708	BRD3	BRD3	NA	NA	ENSG00000169925	NA	NA	rs532553681-AT	rs532553681	1	141832041	intron_variant	FALSE	0.6085	4e-10	9.397940008672037	NA	0.0257505	[0.018-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.6085	NA	0.0257505
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p36.33	1	2214726	RP11-181G12.4	FAAP20 - SKI	ENSG00000162585	ENSG00000157933	NA	2006	13593	rs78265569-A	rs78265569	0	78265569	intron_variant	TRUE	0.0894	5e-10	9.301029995663981	NA	0.04037569	[0.028-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0894	NA	0.04037569
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p36.32	1	3063713	LINC00982	PRDM16-DT	NA	NA	ENSG00000177133	NA	NA	rs2072732-C	rs2072732	0	2072732	non_coding_transcript_exon_variant	FALSE	0.1916	1e-14	14	NA	0.03619666	[0.027-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1916	NA	0.03619666
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p36.32	1	3080038	PRDM16	PRDM16	NA	NA	ENSG00000142611	NA	NA	rs1569419-C	rs1569419	0	1569419	intron_variant	FALSE	0.7644	7e-24	23.154901959985743	NA	0.04387502	[0.035-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7644	NA	0.04387502
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p36.23	1	8857043	ENO1	RERE - ENO1	ENSG00000142599	ENSG00000074800	NA	8122	3957	rs11121246-G	rs11121246	0	11121246	regulatory_region_variant	TRUE	0.5001	3e-16	15.522878745280337	NA	0.02979656	[0.023-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5001	NA	0.02979656
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p36.22	1	11968598	PLOD1	PLOD1	NA	NA	ENSG00000083444	NA	NA	rs11121845-T	rs11121845	0	11121845	intron_variant	FALSE	0.4632	2e-38	37.69897000433602	NA	0.04850045	[0.041-0.056] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4632	NA	0.04850045
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p36.13	1	19423058	CAPZB	CAPZB	NA	NA	ENSG00000077549	NA	NA	rs11456569-CT	rs11456569	0	11456569	intron_variant	FALSE	0.3455	4e-11	10.397940008672037	NA	0.02539743	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3455	NA	0.02539743
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p36.11	1	24705677	intergenic	SRRM1 - CLIC4	ENSG00000133226	ENSG00000169504	NA	32396	39705	rs66530629-A	rs66530629	0	66530629	intron_variant	TRUE	0.2497	2e-13	12.698970004336019	NA	0.03107871	[0.023-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2497	NA	0.03107871
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	1p36.11	1	25235176	SYF2	SYF2 - RSRP1	ENSG00000117614	ENSG00000117616	NA	2674	7073	rs55794721-A	rs55794721	0	55794721	intergenic_variant	TRUE	0.4119	7e-37	36.15490195998574	NA	0.04743355	[0.04-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4119	NA	0.04743355
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	10q23.33	10	94660582	CYP2C9, CYP2C18, CYP2C19	CTBP2P2 - CYP2C18	ENSG00000235746	ENSG00000108242	NA	12586	23147	rs137891020-T	rs137891020	1	9732195	intergenic_variant	TRUE	0.19	1e-14	14	NA	6.29	[NR] unit decrease	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.19	6.29	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	10q23.33	10	94839753	NR	CYP2C19	NA	NA	ENSG00000165841	NA	NA	rs7915414-A	rs7915414	0	7915414	intron_variant	FALSE	0.2	3e-14	13.522878745280337	NA	6.01	[NR] unit decrease	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.2	6.01	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	10q23.33	10	94462696	RNF2	TBC1D12	NA	NA	ENSG00000108239	NA	NA	rs200124419-D	rs200124419	0	200124419	intron_variant	FALSE	0.17	7e-13	12.154901959985743	NA	7.6	[NR] unit decrease	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.17	7.6	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	3p25.3	3	8945549	RAD18	RAD18	NA	NA	ENSG00000070950	NA	NA	rs187941554-A	rs187941554	0	187941554	intron_variant	FALSE	0.01	3e-11	10.522878745280337	NA	25.16	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.01	25.16	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	3p25.3	3	8351128	NR	LMCD1-AS1	NA	NA	ENSG00000227110	NA	NA	rs149772317-A	rs149772317	0	149772317	intron_variant	FALSE	0.01	6e-10	9.221848749616356	NA	17.14	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.01	17.14	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	3p25.2	3	11750143	NR	VGLL4	NA	NA	ENSG00000144560	NA	NA	rs147119990-A	rs147119990	0	147119990	intron_variant	FALSE	0.01	2e-9	8.698970004336019	NA	20.21	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.01	20.21	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q11.2	17	33229663	ASIC2	ASIC2	NA	NA	ENSG00000108684	NA	NA	rs80343429-A	rs80343429	0	80343429	intron_variant	FALSE	0.05	1e-8	8	NA	8.01	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.05	8.01	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q12	17	35024500	NR	RFFL	NA	NA	ENSG00000092871	NA	NA	rs117014945-A	rs117014945	0	117014945	intron_variant	FALSE	0.05	1e-7	7	NA	7.92	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.05	7.92	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q12	17	34888094	NR	NA - CCT6B	NA	ENSG00000132141	NA	NA	39765	rs116994735-A	rs116994735	0	116994735	intergenic_variant	TRUE	0.05	1e-7	7	NA	7.33	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.05	7.33	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q12	17	34678675	NR	TMEM132E - NA	ENSG00000181291	NA	NA	39357	NA	rs4795963-T	rs4795963	0	4795963	intergenic_variant	TRUE	0.13	1e-7	7	NA	5.01	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.13	5.01	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	7q21.2	7	92861969	LOC101927497	CDK6-AS1	NA	NA	ENSG00000237819	NA	NA	rs73407739-T	rs73407739	0	73407739	intron_variant	FALSE	0.01	2e-7	6.698970004336019	NA	16.83	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.01	16.83	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	3p25.3	3	10363377	NR	ATP2B2	NA	NA	ENSG00000157087	NA	NA	rs11923545-T	rs11923545	0	11923545	intron_variant	FALSE	0.01	3e-7	6.522878745280337	NA	15.88	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.01	15.88	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q12	17	35938396	NR	LYZL6, LYZL6	NA	NA	ENSG00000275722, ENSG00000277042	NA	NA	rs187439464-T	rs187439464	0	187439464	intron_variant	FALSE	0.06	3e-7	6.522878745280337	NA	7.33	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.06	7.33	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q12	17	36131293	NR	RN7SL301P - TBC1D3B	ENSG00000276014	ENSG00000282750	NA	20846	34390	rs189886302-T	rs189886302	0	189886302	intron_variant	TRUE	0.03	3e-7	6.522878745280337	NA	13.08	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.03	13.08	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	3p25.3	3	10236760	NR	IRAK2	NA	NA	ENSG00000134070	NA	NA	rs115267786-G	rs115267786	0	115267786	intron_variant	FALSE	0.01	4e-7	6.3979400086720375	NA	15.57	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.01	15.57	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q12	17	35463968	NR	SLFN13 - SLFN12L	ENSG00000154760	ENSG00000286065	NA	15131	10936	rs72825991-A	rs72825991	0	72825991	intergenic_variant	TRUE	0.04	5e-7	6.301029995663981	NA	9.56	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.04	9.56	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	3p26.1	3	7702351	NR	GRM7	NA	NA	ENSG00000196277	NA	NA	rs148515972-A	rs148515972	0	148515972	intron_variant	FALSE	0.02	5e-7	6.301029995663981	NA	12.48	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.02	12.48	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q11.2	17	28493453	NR	SLC13A2	NA	NA	ENSG00000007216	NA	NA	rs142179566-A	rs142179566	0	142179566	intron_variant	FALSE	0.02	6e-7	6.221848749616356	NA	13.31	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.02	13.31	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	2q14.3	2	122451824	Intergenic	NA	NA	NA	NA	NA	NA	rs181524103-G	rs181524103	0	181524103	intron_variant	TRUE	0.03	7e-7	6.154901959985743	NA	12.01	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.03	12.01	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	16p13.2	16	9062124	Intergenic	USP7 - C16orf72	ENSG00000187555	ENSG00000182831	NA	86796	29520	rs138852022-G	rs138852022	0	138852022	regulatory_region_variant	TRUE	0.01	7e-7	6.154901959985743	NA	17.04	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.01	17.04	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q12	17	35738884	NR	RASL10B, TAF15	NA	NA	ENSG00000270885, ENSG00000270647	NA	NA	rs73990293-C	rs73990293	0	73990293	intron_variant	FALSE	0.08	7e-7	6.154901959985743	NA	6.55	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.08	6.55	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	3p25.3	3	10616073	NR	ATP2B2	NA	NA	ENSG00000157087	NA	NA	rs114622784-G	rs114622784	0	114622784	intron_variant	FALSE	0.01	8e-7	6.096910013008056	NA	18.11	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.01	18.11	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q12	17	35265427	NR	SLFN5	NA	NA	ENSG00000166750	NA	NA	rs185910438-G	rs185910438	0	185910438	missense_variant	FALSE	0.03	8e-7	6.096910013008056	NA	9.61	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.03	9.61	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	17q11.2	17	29088245	NR	MYO18A	NA	NA	ENSG00000196535	NA	NA	rs144975552-G	rs144975552	0	144975552	intron_variant	FALSE	0.03	9e-7	6.045757490560675	NA	11.96	[NR] unit increase	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.03	11.96	NA
2017-06-29	28207573	Backman JD	2017-04-01	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/28207573	Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.	Clopidogrel active metabolite levels	513 Amish individuals	NA	5q35.2	5	174764462	Intergenic	MIR4634 - NA	ENSG00000266890	NA	NA	12675	NA	rs6892003-A	rs6892003	0	6892003	intron_variant	TRUE	0.71	1e-6	6	NA	3.27	[NR] unit decrease	Affymetrix [7884700] (imputed)	N	clopidogrel metabolite measurement	http://www.ebi.ac.uk/efo/EFO_0007966	GCST004264	Genome-wide genotyping array	0.71	3.27	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7p15.2	7	26031145	intergenic	MIR148A - NA	ENSG00000199085	NA	NA	81159	NA	rs62446306-C	rs62446306	0	62446306	intergenic_variant	TRUE	0.2143	6e-10	9.221848749616356	NA	0.02714734	[0.019-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2143	NA	0.02714734
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7p15.1	7	28237488	JAZF1-AS1	JAZF1-AS1	NA	NA	ENSG00000234336	NA	NA	rs2158799-G	rs2158799	0	2158799	intron_variant	FALSE	0.6081	3e-15	14.522878745280337	NA	0.0292199	[0.022-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.6081	NA	0.0292199
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7p15.1	7	28684757	CREB5	CREB5	NA	NA	ENSG00000146592	NA	NA	rs56388170-T	rs56388170	0	56388170	intron_variant	FALSE	0.2956	5e-49	48.30102999566398	NA	0.05842803	[0.051-0.066] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2956	NA	0.05842803
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7p13	7	44969742	MYO1G	MYO1G	NA	NA	ENSG00000136286	NA	NA	rs3735485-G	rs3735485	0	3735485	missense_variant	FALSE	0.8456	2e-9	8.698970004336019	NA	0.02964378	[0.02-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.8456	NA	0.02964378
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7p12.2	7	50218107	intergenic	SPATA48 - IKZF1	ENSG00000164500	ENSG00000185811	NA	58851	85961	rs11769630-A	rs11769630	0	11769630	intron_variant	TRUE	0.0748	2e-54	53.69897000433602	NA	0.1076488	[0.094-0.121] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0748	NA	0.1076488
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7p12.2	7	50267738	intergenic	SPATA48 - IKZF1	ENSG00000164500	ENSG00000185811	NA	108482	36330	rs4385425-G	rs4385425	0	4385425	regulatory_region_variant	TRUE	0.3211	9e-71	70.04575749056067	NA	0.0681105	[0.061-0.076] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.3211	NA	0.0681105
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7p12.2	7	50285056	intergenic	NA - IKZF1	NA	ENSG00000185811	NA	NA	19012	rs4917131-G	rs4917131	0	4917131	intergenic_variant	TRUE	0.807	3e-29	28.522878745280337	NA	0.0517505	[0.043-0.061] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.807	NA	0.0517505
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7p12.2	7	50330658	IKZF1	IKZF1	NA	NA	ENSG00000185811	NA	NA	rs149007767-T	rs149007767	0	149007767	intron_variant	FALSE	0.1618	2e-67	66.69897000433602	NA	0.08867422	[0.079-0.099] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.1618	NA	0.08867422
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7p12.2	7	50369033	IKZF1	IKZF1	NA	NA	ENSG00000185811	NA	NA	rs78697948-G	rs78697948	0	78697948	3_prime_UTR_variant	FALSE	0.0728	1e-30	30	NA	0.07982786	[0.066-0.093] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0728	NA	0.07982786
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7p12.2	7	50369250	IKZF1	IKZF1	NA	NA	ENSG00000185811	NA	NA	rs12718731-G	rs12718731	0	12718731	3_prime_UTR_variant	FALSE	0.4008	2e-15	14.698970004336019	NA	0.02899767	[0.022-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.4008	NA	0.02899767
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7q11.21	7	65652031	INTS4L2	INTS4P2	NA	NA	ENSG00000273024	NA	NA	rs201697372-G	rs201697372	0	201697372	intron_variant	FALSE	0.4722	1e-9	9	NA	0.02284061	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.4722	NA	0.02284061
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7q11.23	7	73642420	intergenic	MLXIPL - VPS37D	ENSG00000009950	ENSG00000176428	NA	17877	25411	rs6957745-C	rs6957745	0	6957745	intergenic_variant	TRUE	0.2032	4e-11	10.397940008672037	NA	0.02946504	[0.021-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2032	NA	0.02946504
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7q21.2	7	92607515	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs4272-G	rs4272	0	4272	3_prime_UTR_variant	FALSE	0.2111	2e-28	27.69897000433602	NA	0.0486948	[0.04-0.057] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.2111	NA	0.0486948
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	7q33	7	138196944	intergenic	Y_RNA - NA	ENSG00000199964	NA	NA	21808	NA	rs7785014-C	rs7785014	0	7785014	regulatory_region_variant	TRUE	0.6715	2e-10	9.698970004336019	NA	0.02435289	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.6715	NA	0.02435289
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	8p23.1	8	6841372	GS1-24F4.2	GS1-24F4.2, GS1-24F4.2	NA	NA	ENSG00000285156, ENSG00000245857	NA	NA	rs881362-G	rs881362	0	881362	intron_variant	FALSE	0.4993	5e-16	15.301029995663981	NA	0.02927692	[0.022-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.4993	NA	0.02927692
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	8p23.1	8	7023403	intergenic	DEFA3 - DEFA11P	ENSG00000284835	ENSG00000234178	NA	5106	5238	rs7826487-G	rs7826487	0	7826487	regulatory_region_variant	TRUE	0.1174	2e-22	21.69897000433602	NA	0.05472916	[0.044-0.066] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.1174	NA	0.05472916
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	8p23.1	8	7048518	intergenic	DEFA7P - DEFA5	ENSG00000206042	ENSG00000285251	NA	9079	6786	rs11137087-G	rs11137087	0	11137087	intergenic_variant	TRUE	0.6314	2e-26	25.69897000433602	NA	0.03958353	[0.032-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.6314	NA	0.03958353
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	8p11.21	8	41774041	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs67464700-C	rs67464700	1	55944545	intron_variant	FALSE	0.6345	2e-11	10.698970004336019	NA	0.02550277	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.6345	NA	0.02550277
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	8q11.21	8	47739071	CEBPD	CEBPD - PRKDC	ENSG00000221869	ENSG00000253729	NA	907	34040	rs45577137-G	rs45577137	0	45577137	regulatory_region_variant	TRUE	0.046	2e-19	18.69897000433602	NA	0.08065189	[0.063-0.098] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.046	NA	0.08065189
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	8q12.2	8	60738272	CHD7	CHD7	NA	NA	ENSG00000171316	NA	NA	rs7846314-T	rs7846314	0	7846314	intron_variant	FALSE	0.1866	5e-36	35.30102999566398	NA	0.05759455	[0.049-0.067] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.1866	NA	0.05759455
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	8q23.3	8	115589675	TRPS1	TRPS1	NA	NA	ENSG00000104447	NA	NA	rs6469606-T	rs6469606	0	6469606	intron_variant	FALSE	0.5667	6e-22	21.221848749616356	NA	0.03488275	[0.028-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.5667	NA	0.03488275
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	8q24.21	8	129596822	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs28500514-C	rs28500514	0	28500514	intron_variant	FALSE	0.5691	2e-63	62.69897000433602	NA	0.06092761	[0.054-0.068] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.5691	NA	0.06092761
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	8q24.21	8	129614582	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs77527100-G	rs77527100	0	77527100	intron_variant	FALSE	0.0526	4e-20	19.397940008672037	NA	0.07408167	[0.058-0.09] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0526	NA	0.07408167
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	8q24.21	8	129666460	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs138628047-C	rs138628047	0	138628047	intron_variant	FALSE	0.0078	6e-16	15.221848749616356	NA	0.1746701	[0.13-0.22] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.0078	NA	0.1746701
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte percentage of myeloid white cells	169,545 European ancestry individuals	NA	9p24.3	9	305428	DOCK8	DOCK8	NA	NA	ENSG00000107099	NA	NA	rs1969949-G	rs1969949	0	1969949	intron_variant	FALSE	0.7214	2e-9	8.698970004336019	NA	0.02414538	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte percentage of myeloid white cells	http://www.ebi.ac.uk/efo/EFO_0007997	GCST004608	Genome-wide genotyping array	0.7214	NA	0.02414538
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	13q32.2	13	97620648	RAP2A	NA	NA	NA	NA	NA	NA	rs9300430-C	rs9300430	0	9300430	intergenic_variant	TRUE	NR	1e-9	9	(Gammaproteobacteria class)	0.61	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	1p35.1	1	33073363	ADC, TRIM62, AK2	AK2	NA	NA	ENSG00000004455	NA	NA	rs804427-?	rs804427	0	804427	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.79	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.79
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	14q23.1	14	60392043	SIX6, C14orf39, SIX1	LINC02322 - C14orf39	ENSG00000258556	ENSG00000179008	NA	68136	4426	rs986417-C	rs986417	0	986417	intergenic_variant	TRUE	NR	3e-9	8.522878745280337	(Unclassified Acidaminococcaceae)	1.4	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	3q24	3	146550829	PLSCR1	PLSCR1 - RNU6-428P	ENSG00000188313	ENSG00000199812	NA	5973	20648	rs13099587-?	rs13099587	0	13099587	intergenic_variant	TRUE	NR	5e-8	7.301029995663981	NA	0.7	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.7
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	4q24	4	101980665	BANK1	BANK1	NA	NA	ENSG00000153064	NA	NA	rs60500975-?	rs60500975	0	60500975	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.82	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.82
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	7q36.1	7	151823399	PRKAG2	PRKAG2	NA	NA	ENSG00000106617	NA	NA	rs35148810-?	rs35148810	0	35148810	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.83	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.83
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	16p12.1	16	27270108	NSMCE1, FLJ21408, KDM8	NSMCE1-DT	NA	NA	ENSG00000245888	NA	NA	rs12149695-A	rs12149695	0	12149695	non_coding_transcript_exon_variant	FALSE	NR	2e-9	8.698970004336019	(OTU10032 unclassified Enterobacteriaceae)	0.61	unit increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	8p21.3	8	20028423	LPL	LPL - RPL30P9	ENSG00000175445	ENSG00000242709	NA	61164	84920	rs138022915-?	rs138022915	1	11984698	intergenic_variant	TRUE	NR	5e-8	7.301029995663981	NA	0.73	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.73
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	18p11.22	18	10566407	NAPG	NAPG - LINC01887	ENSG00000134265	ENSG00000266604	NA	13643	45897	rs11877825-G	rs11877825	0	11877825	regulatory_region_variant	TRUE	NR	3e-11	10.522878745280337	(Erysipelotrichia class)	0.27	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	18p11.22	18	10566407	NAPG	NAPG - LINC01887	ENSG00000134265	ENSG00000266604	NA	13643	45897	rs11877825-G	rs11877825	0	11877825	regulatory_region_variant	TRUE	NR	3e-11	10.522878745280337	(Erysipelotrichales order)	0.27	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	19q13.13	19	38029684	SIPA1L3	SIPA1L3	NA	NA	ENSG00000105738	NA	NA	rs148330122-C	rs148330122	0	148330122	intron_variant	FALSE	NR	1e-9	9	(Bacilli class)	0.48	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	15q26.1	15	89091183	ABHD2	ABHD2	NA	NA	ENSG00000140526	NA	NA	rs293377-?	rs293377	0	293377	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.7	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.7
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	16q24.1	16	84546925	KIAA1609	MEAK7	NA	NA	ENSG00000140950	NA	NA	rs8055365-?	rs8055365	0	8055365	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.7	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.7
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	1p36.21	1	15760765	FBLIM1	FBLIM1	NA	NA	ENSG00000162458	NA	NA	rs938295-C	rs938295	0	938295	intron_variant	FALSE	NR	2e-8	7.698970004336019	(Unclassified Enterobacteriaceae)	0.49	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	1p34.3	1	37278760	LINC01137	RNA5SP43 - RPS29P6	ENSG00000252368	ENSG00000230451	NA	13974	52092	rs75036654-C	rs75036654	0	75036654	intron_variant	TRUE	NR	5e-10	9.301029995663981	(Unclassified Acidaminococcaceae)	1.39	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	1p13.2	1	111870400	C1orf183	KCND3	NA	NA	ENSG00000171385	NA	NA	rs597205-T	rs597205	0	597205	intron_variant	FALSE	NR	8e-9	8.096910013008056	(OTU13305 FecalibacteriumSpecies-level OTU)	0.62	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	2p25.1	2	9665794	RP11-521D12.1	YWHAQ - RNU4-73P	ENSG00000134308	ENSG00000200034	NA	34797	74849	rs4669413-T	rs4669413	0	4669413	intron_variant	TRUE	NR	1e-8	8	(Blautia genus)	0.18	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	2q12.1	2	102598951	SLC9A2	SLC9A4 - SLC9A2	ENSG00000180251	ENSG00000115616	NA	64979	20602	rs79387448-C	rs79387448	0	79387448	intergenic_variant	TRUE	NR	8e-11	10.096910013008056	(Blautia genus)	0.31	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	2q14.3	2	128700224	HS6ST1	NA	NA	NA	NA	NA	NA	rs10928827-G	rs10928827	0	10928827	intergenic_variant	TRUE	NR	1e-8	8	(Bacilli class)	0.22	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	7p12.3	7	48364154	ABCA13	ABCA13	NA	NA	ENSG00000179869	NA	NA	rs17661843-T	rs17661843	0	17661843	intron_variant	FALSE	NR	4e-14	13.397940008672037	(Unclassified Acidaminococcaceae)	1.4	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	2q35	2	217044262	AC007557.1	OTOF - NA	ENSG00000115155	NA	NA	190485506	NA	rs4621152-C	rs4621152	0	4621152	regulatory_region_variant	TRUE	NR	1e-8	8	(Gammaproteobacteria class)	0.29	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	2q36.3	2	227654802	C2orf83	C2orf83 - SCYGR5	ENSG00000042304	ENSG00000284667	NA	6196	12002	rs56006724-A	rs56006724	0	56006724	regulatory_region_variant	TRUE	NR	6e-10	9.221848749616356	(Unclassified Acidaminococcaceae)	0.88	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	8q24.3	8	138914773	COL22A1	COL22A1 - NA	ENSG00000169436	NA	NA	732	NA	rs2318350-T	rs2318350	0	2318350	regulatory_region_variant	TRUE	NR	4e-9	8.397940008672037	(OTU10032 unclassified Enterobacteriaceae Species-level OTU)	1.15	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	9q21.11	9	68552962	C9orf71	TMEM252-DT	NA	NA	ENSG00000226337	NA	NA	rs17085775-C	rs17085775	0	17085775	intron_variant	FALSE	NR	2e-8	7.698970004336019	(OTU10032 unclassified Enterobacteriaceae)	1.03	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	10p14	10	6989182	RP11-554I8.2	NA	NA	NA	NA	NA	NA	rs7083345-T	rs7083345	0	7083345	intron_variant	TRUE	NR	3e-9	8.522878745280337	(Lactobacillales order)	0.24	unit increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	10p14	10	6989182	RP11-554I8.2	NA	NA	NA	NA	NA	NA	rs7083345-T	rs7083345	0	7083345	intron_variant	TRUE	NR	3e-10	9.522878745280337	(Bacilli class)	0.25	unit increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	11q24.1	11	122227835	RP11-166D19.1	MIR100HG	NA	NA	ENSG00000255248	NA	NA	rs7113056-C	rs7113056	0	7113056	intron_variant	FALSE	NR	2e-13	12.698970004336019	(Lactobacillales order)	0.5	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	12p13.32	12	3273397	PRMT8	TSPAN9	NA	NA	ENSG00000011105	NA	NA	rs479105-T	rs479105	0	479105	intron_variant	FALSE	NR	1e-8	8	(Bacilli class)	0.22	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	12p13.32	12	4670147	AKAP3, NDUFA9, GALNT8, RP11-234B24.2	NDUFA9	NA	NA	ENSG00000139180	NA	NA	rs1009634-G	rs1009634	0	1009634	intron_variant	FALSE	NR	7e-9	8.154901959985743	(OTU10032 unclassified Enterobacteriaceae Species-level OTU)	1.31	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	5q33.3	5	158940241	EBF1	EBF1	NA	NA	ENSG00000164330	NA	NA	rs62385385-?	rs62385385	0	62385385	intron_variant	FALSE	NR	7e-22	21.154901959985743	NA	1.247	[1.192-1.304]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.247	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	Xp11.21	X	57975900	ZXDA	MYCLP2 - KRT8P17	ENSG00000228004	ENSG00000235124	NA	41097	8786	rs111763724-?	rs111763724	0	111763724	intergenic_variant	TRUE	NR	6e-20	19.221848749616356	NA	1.6750418	[1.49-1.88]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.6750418	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	17q21.31	17	46088713	KANSL1	KANSL1, KANSL1, KANSL1	NA	NA	ENSG00000120071, ENSG00000275867, ENSG00000278458	NA	NA	rs201408539-?	rs201408539	0	201408539	intron_variant	FALSE	NR	8e-20	19.096910013008056	NA	1.338	[1.257-1.425]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.338	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	3q25.1	3	151937074	SUCNR1, MBNL1	AADACL2-AS1 - NA	ENSG00000242908	NA	NA	8899	NA	rs4679956-?	rs4679956	0	4679956	intergenic_variant	TRUE	NR	5e-19	18.30102999566398	NA	1.223	[1.170-1.279]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.223	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	Xp11.21	X	55923583	RRAGB, KLF8	NA - GOT2P6	NA	ENSG00000214745	NA	NA	37625	rs143149578-?	rs143149578	0	143149578	intron_variant	TRUE	NR	6e-18	17.221848749616356	NA	1.7123288	[1.51-1.95]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.7123288	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	2q35	2	218881570	WNT10A	WNT10A	NA	NA	ENSG00000135925	NA	NA	rs74333950-?	rs74333950	0	74333950	intron_variant	FALSE	NR	2e-16	15.698970004336019	NA	1.3089005	[1.23-1.40]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.3089005	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	2p23.1	2	31580756	SRD5A2	SRD5A2	NA	NA	ENSG00000277893	NA	NA	rs9282858-?	rs9282858	0	9282858	missense_variant	FALSE	NR	2e-15	14.698970004336019	NA	1.6638935	[1.47-1.89]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.6638935	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	18q12.3	18	45228094	SLC14A2	SLC14A2	NA	NA	ENSG00000132874	NA	NA	rs34800162-?	rs34800162	0	34800162	intron_variant	FALSE	NR	8e-15	14.096910013008056	NA	1.217	[1.158-1.278]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.217	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	1p12	1	118339066	SPAG17, TBX15	RNA5SP56 - MDM4	ENSG00000222209	ENSG00000198625	NA	74577	86177313	rs12083887-?	rs12083887	0	12083887	regulatory_region_variant	TRUE	NR	9e-14	13.045757490560675	NA	1.1862396	[1.13-1.24]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1862396	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	6p24.3	6	9327323	SLC35B3, OFCC1	HULC - NA	ENSG00000285219	NA	NA	33190	NA	rs9357047-?	rs9357047	0	9357047	intergenic_variant	TRUE	NR	3e-13	12.522878745280337	NA	1.1806375	[1.13-1.23]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1806375	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	8q23.1	8	108585572	EMC2, TMEM74	EMC2 - TMEM74	ENSG00000104412	ENSG00000164841	NA	96376	21278	rs79437808-?	rs79437808	0	79437808	intron_variant	TRUE	NR	4e-13	12.397940008672037	NA	2.153	[1.738-2.668]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	2.153	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	Xp11.21	X	55107412	PAGE2B, FAM104B	PAGE2 - FAM104B	ENSG00000234068	ENSG00000182518	NA	14570	35690	rs185597083-?	rs185597083	0	185597083	intergenic_variant	TRUE	NR	8e-13	12.096910013008056	NA	1.388	[1.267-1.520]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.388	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	10q26.13	10	124655362	FAM53B	FAM53B	NA	NA	ENSG00000189319	NA	NA	rs3781458-?	rs3781458	0	3781458	intron_variant	FALSE	NR	1e-12	12	NA	1.1778563	[1.12-1.23]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1778563	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	17q22	17	57153807	AKAP1, MSI2	AKAP1 - LINC02563	ENSG00000121057	ENSG00000263520	NA	32461	8303734	rs62060349-?	rs62060349	0	62060349	intergenic_variant	TRUE	NR	2e-12	11.698970004336019	NA	1.172333	[1.12-1.23]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.172333	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	10q22.3	10	76436854	C10orf11	LRMDA	NA	NA	ENSG00000148655	NA	NA	rs11593840-?	rs11593840	0	11593840	intron_variant	FALSE	NR	2e-12	11.698970004336019	NA	1.1737089	[1.12-1.23]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1737089	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	12p12.1	12	26273738	SSPN, ITPR2	SSPN	NA	NA	ENSG00000123096	NA	NA	rs9300169-?	rs9300169	0	9300169	non_coding_transcript_exon_variant	FALSE	NR	4e-12	11.397940008672037	NA	1.1918951	[1.13-1.25]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1918951	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	2p14	2	67851717	ETAA1, C1D	LINC01812 - NA	ENSG00000237013	NA	NA	26155	NA	rs6546334-?	rs6546334	0	6546334	intergenic_variant	TRUE	NR	6e-12	11.221848749616356	NA	1.1750882	[1.12-1.23]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1750882	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	6p25.3	6	396321	IRF4	IRF4	NA	NA	ENSG00000137265	NA	NA	rs12203592-?	rs12203592	0	12203592	intron_variant	FALSE	NR	4e-11	10.397940008672037	NA	1.22	[1.150-1.294]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.22	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	21q22.12	21	34835870	RUNX1	RUNX1	NA	NA	ENSG00000159216	NA	NA	rs68088846-?	rs68088846	0	68088846	intron_variant	FALSE	NR	4e-11	10.397940008672037	NA	1.2077295	[1.14-1.28]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.2077295	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	1p36.11	1	25171684	RUNX3, SYF2	IFITM3P7 - SYF2	ENSG00000233419	ENSG00000117614	NA	46230	50592	rs7534070-?	rs7534070	0	7534070	intergenic_variant	TRUE	NR	5e-11	10.301029995663981	NA	1.201923	[1.14-1.27]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.201923	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	6q22.32	6	126733443	CENPW, RSPO3	RPS4XP9 - NA	ENSG00000217404	NA	NA	49596	NA	rs1262557-?	rs1262557	0	1262557	intron_variant	TRUE	NR	5e-10	9.301029995663981	NA	1.15	[1.100-1.202]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.15	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	11p11.2	11	44389312	ALX4, CD82	ALX4 - NA	ENSG00000052850	NA	NA	79173	NA	rs11037975-?	rs11037975	0	11037975	intergenic_variant	TRUE	NR	6e-10	9.221848749616356	NA	1.1709602	[1.11-1.23]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1709602	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	4q25	4	106961892	DKK2	DKK2	NA	NA	ENSG00000155011	NA	NA	rs78311490-?	rs78311490	0	78311490	intron_variant	FALSE	NR	7e-10	9.154901959985743	NA	1.3210039	[1.21-1.45]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.3210039	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	1q24.2	1	170372381	METTL11B, GORAB	HAUS4P1 - GORAB-AS1	ENSG00000226967	ENSG00000231407	NA	2014	88072	rs78003935-?	rs78003935	0	78003935	intergenic_variant	TRUE	NR	1e-9	9	NA	1.1614403	[1.11-1.22]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1614403	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	15q23	15	69749354	RPLP1, TLE3	DRAIC	NA	NA	ENSG00000245750	NA	NA	rs7177657-?	rs7177657	0	7177657	intron_variant	FALSE	NR	1e-9	9	NA	1.2610341	[1.17-1.36]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.2610341	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	20q13.13	20	50278219	CEBPB	PELATON	NA	NA	ENSG00000224397	NA	NA	rs3088220-T	rs3088220	0	3088220	non_coding_transcript_exon_variant	FALSE	NR	3e-9	8.522878745280337	(GO:0071805|BP|04|potassium ion transmembrane transport)	5.951341	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.951341	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	4p14	4	36066949	ARAP2	ARAP2	NA	NA	ENSG00000047365	NA	NA	rs12645801-T	rs12645801	0	12645801	3_prime_UTR_variant	FALSE	NR	1e-8	8	(PWY-6518_glycocholate_metabolism_(bacteria))	5.735547	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.735547	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	3p14.2	3	63659018	SNTN	SNTN	NA	NA	ENSG00000188817	NA	NA	rs924067-T	rs924067	0	924067	intron_variant	FALSE	NR	1e-8	8	(PWY-6215_4-chlorobenzoate_degradation)	5.6681013	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.6681013	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	22q12.1	22	25887747	MYO18B	MYO18B, MYO18B-AS1	NA	NA	ENSG00000133454, ENSG00000231933	NA	NA	rs2285198-T	rs2285198	0	2285198	intron_variant	FALSE	NR	4e-9	8.397940008672037	(GO:0008283|BP|02|cell proliferation)	5.889772	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.889772	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	14q32.2	14	98726103	C14orf177	C14orf177 - NA	ENSG00000176605	NA	NA	8342	NA	rs17097744-C	rs17097744	0	17097744	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	(GO:0042823|BP|05|pyridoxal phosphate biosynthetic process)	5.6328077	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.6328077	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	1p13.3	1	110227601	KCNC4	KCNC4	NA	NA	ENSG00000116396	NA	NA	rs958798-T	rs958798	0	958798	intron_variant	FALSE	NR	2e-8	7.698970004336019	(GO:0045944|BP|08|positive regulation of transcription from RNA polymerase II promoter)	5.618814	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.618814	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	2p13.3	2	70874296	VAX2	CD207 - LINC01143	ENSG00000116031	ENSG00000237751	NA	38480	13575	rs6546647-T	rs6546647	0	6546647	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	(GO:0048598|BP|03|embryonic morphogenesis)	5.6177616	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.6177616	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	3q23	3	139564620	NMNAT3	NMNAT3	NA	NA	ENSG00000163864	NA	NA	rs1497266-C	rs1497266	0	1497266	intron_variant	FALSE	NR	2e-8	7.698970004336019	(GO:0009229|BP|05|thiamine diphosphate biosynthetic process)	5.590062	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.590062	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	12p13.31	12	8244933	FAM90A1	FAM86FP - ENPP7P5	ENSG00000164845	ENSG00000256589	NA	1985	9594	rs9669179-G	rs9669179	0	9669179	intron_variant	TRUE	NR	3e-8	7.522878745280337	(GO:0009231|BP|04|riboflavin biosynthetic process)	5.5538855	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.5538855	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	11q25	11	131343979	NTM	NA - NTM	NA	ENSG00000182667	NA	NA	26499	rs11606643-A	rs11606643	0	11606643	intron_variant	TRUE	NR	3e-8	7.522878745280337	(GO:0045087|BP|03|innate immune response)	5.5346055	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.5346055	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	1p34.2	1	41807982	HIVEP3	HIVEP3	NA	NA	ENSG00000127124	NA	NA	rs12563071-T	rs12563071	0	12563071	intron_variant	FALSE	NR	3e-8	7.522878745280337	(UBISYN-PWY_superpathway_of_ubiquinol-8_biosynthesis_(prokaryotic))	5.5680895	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.5680895	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	18p11.21	18	13329916	LDLRAD4	LDLRAD4	NA	NA	ENSG00000168675	NA	NA	rs113062739-A	rs113062739	0	113062739	intron_variant	FALSE	NR	3e-8	7.522878745280337	(PWY-5862_superpathway_of_demethylmenaquinol-9_biosynthesis)	5.535196	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.535196	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	12p11.22	12	27804600	KLHL42	KLHL42 - RN7SKP15	ENSG00000087448	ENSG00000201612	NA	1560	1482	rs7133214-G	rs7133214	0	7133214	regulatory_region_variant	TRUE	NR	3e-8	7.522878745280337	(PWY-7527_L-methionine_salvage_cycle_III)	5.562922	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.562922	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	12p11.22	12	27804600	KLHL42	KLHL42 - RN7SKP15	ENSG00000087448	ENSG00000201612	NA	1560	1482	rs7133214-G	rs7133214	0	7133214	regulatory_region_variant	TRUE	NR	3e-8	7.522878745280337	(PWY-7528_L-methionine_salvage_cycle_I_(bacteria_and_plants))	5.5373735	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.5373735	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	13q21.2	13	60250568	DIAPH3	LINC00434 - TARDBPP2	ENSG00000227336	ENSG00000238213	NA	35622	24208	rs7992913-C	rs7992913	0	7992913	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	(PWY-3001_superpathway_of_L-isoleucine_biosynthesis_I)	5.55539	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.55539	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	11q12.2	11	61064810	CD6, CD5	CD6 - CD5	ENSG00000013725	ENSG00000110448	NA	44433	37679	rs650258-T	rs650258	0	650258	intron_variant	TRUE	NR	2e-7	6.698970004336019	(GO:0009231|BP|04|riboflavin biosynthetic process)	5.1726856	Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.1726856	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	2p25.3	2	1851795	MYT1L	MYT1L	NA	NA	ENSG00000186487	NA	NA	rs4553849-A	rs4553849	0	4553849	intron_variant	FALSE	NR	3e-8	7.522878745280337	(PWY-4722_creatinine_degradation_II)	5.51509	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.51509	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	6q15	6	88192771	CNR1	CNR1 - ACTBP8	ENSG00000118432	ENSG00000220267	NA	26424	83111	rs6933130-T	rs6933130	0	6933130	intron_variant	TRUE	NR	4e-8	7.3979400086720375	(PWY-5345_superpathway_of_L-methionine_biosynthesis_(by_sulfhydrylation))	5.4949656	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.4949656	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	14q32.13	14	95204550	CLMN	CLMN	NA	NA	ENSG00000165959	NA	NA	rs74773701-G	rs74773701	1	1763730	intron_variant	FALSE	NR	4e-8	7.3979400086720375	(P562-PWY_myo-inositol_degradation_I)	5.478184	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.478184	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	17q12	17	34266955	CCL2, CCL7, CCL11	CCL2 - CCL7	ENSG00000108691	ENSG00000108688	NA	9752	3266	rs3091316-A	rs3091316	0	3091316	regulatory_region_variant	TRUE	NR	6e-7	6.221848749616356	(PWY-6654_phosphopantothenate_biosynthesis_III)	4.9887505	Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.9887505	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	19q13.32	19	44900155	TOMMC40, APOE	TOMM40	NA	NA	ENSG00000130204	NA	NA	rs1160985-T	rs1160985	0	1160985	intron_variant	FALSE	NR	6e-7	6.221848749616356	(GO:0006222|BP|08|UMP biosynthetic process)	4.9816666	Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.9816666	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	11q12.2	11	61064810	CD6, CD5	CD6 - CD5	ENSG00000013725	ENSG00000110448	NA	44433	37679	rs650258-T	rs650258	0	650258	intron_variant	TRUE	NR	1e-6	6	(PWY-5154_L-arginine_biosynthesis_III_(via_N-acetyl-L-citrulline))	4.8267756	Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.8267756	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	1p31.3	1	67281753	IL23R	DNAJB6P4 - IL12RB2	ENSG00000228523	ENSG00000081985	NA	2974	25611	rs12141575-A	rs12141575	0	12141575	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(PWY-6215_4-chlorobenzoate_degradation)	4.768668	Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.768668	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	20q13.12	20	45947863	PCIF1	PCIF1	NA	NA	ENSG00000100982	NA	NA	rs7679-C	rs7679	0	7679	3_prime_UTR_variant	FALSE	NR	2e-6	5.698970004336019	(CRNFORCAT-PWY_creatinine_degradation_I)	4.76667	Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.76667	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	3q13.33	3	122077921	CD86	CD86	NA	NA	ENSG00000114013	NA	NA	rs9282641-A	rs9282641	0	9282641	splice_region_variant	FALSE	NR	2e-6	5.698970004336019	(GO:0003682|MF|02|chromatin binding)	4.7661104	Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.7661104	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	19q13.32	19	44900155	TOMMC40, APOE	TOMM40	NA	NA	ENSG00000130204	NA	NA	rs1160985-T	rs1160985	0	1160985	intron_variant	FALSE	NR	2e-6	5.698970004336019	(GO:0004812|MF|05|aminoacyl-tRNA ligase activity)	4.723705	Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.723705	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	1q32.1	1	206773289	IL10	IL19, IL10	NA	NA	ENSG00000142224, ENSG00000136634	NA	NA	rs1800871-A	rs1800871	0	1800871	5_prime_UTR_variant	FALSE	NR	2e-6	5.698970004336019	(GO:0031461|CC|04|cullin-RING ubiquitin ligase complex)	4.711804	Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.711804	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	11q13.5	11	76590331	C11ORF30, LRRC32	EMSY - LINC02757	ENSG00000158636	ENSG00000255363	NA	37306	17522	rs7927997-T	rs7927997	0	7927997	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(GO:0007267|BP|03|cell-cell signaling)	4.6556125	Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.6556125	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	9q34.2	9	133458632	ADAMTS13, CACFD1, SLC2A6	ADAMTS13	NA	NA	ENSG00000160323	NA	NA	rs4962153-A	rs4962153	0	4962153	intron_variant	FALSE	NR	3e-6	5.522878745280337	(GO:0048598|BP|03|embryonic morphogenesis)	4.6572533	Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.6572533	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	11q13.5	11	76590272	C11ORF30, LRRC32	EMSY - LINC02757	ENSG00000158636	ENSG00000255363	NA	37247	17581	rs7927894-T	rs7927894	0	7927894	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(GO:0007267|BP|03|cell-cell signaling)	4.6556125	Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	4.6556125	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	22q12.2	22	31133057	PLA2G3, INPP5J	INPP5J	NA	NA	ENSG00000185133	NA	NA	rs9917541-?	rs9917541	0	9917541	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.71	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.71
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	14q23.1	14	58060100	SLC35F4, C14orf37	ARMH4	NA	NA	ENSG00000139971	NA	NA	rs9323326-A	rs9323326	0	9323326	intron_variant	FALSE	NR	9e-10	9.045757490560675	(Proteobacteria phylum)	0.21	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	2p22.3	2	33843325	FAM98A	LINC01320	NA	NA	ENSG00000228262	NA	NA	rs4670302-?	rs4670302	0	4670302	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.92	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.92
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	14q32.11	14	90287967	C14orf102	NRDE2	NA	NA	ENSG00000119720	NA	NA	rs11626933-G	rs11626933	0	11626933	intron_variant	FALSE	NR	2e-8	7.698970004336019	(Unclassified Erysipelotrichaceae)	0.24	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	15q14	15	37681337	TMCO5A	NA	NA	NA	NA	NA	NA	rs12442649-G	rs12442649	0	12442649	intergenic_variant	TRUE	NR	4e-8	7.3979400086720375	(OTU15355 Dialister Species-level OTU)	1.49	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	15q22.2	15	59790699	BNIP2	RPS3AP6 - NA	ENSG00000234797	NA	NA	21553	NA	rs35275482-C	rs35275482	0	35275482	intergenic_variant	TRUE	NR	4e-11	10.397940008672037	(Enterobacteriaceae family)	0.54	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	15q22.2	15	59790699	BNIP2	RPS3AP6 - NA	ENSG00000234797	NA	NA	21553	NA	rs35275482-C	rs35275482	0	35275482	intergenic_variant	TRUE	NR	4e-11	10.397940008672037	(Enterobacteriales order)	0.54	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	8p23.2	8	3848285	CSMD1	CSMD1	NA	NA	ENSG00000183117	NA	NA	rs13260600-?	rs13260600	0	13260600	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.77	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.77
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	16q12.1	16	51973264	TOX3	NA - C16orf97	NA	ENSG00000261190	NA	NA	32223	rs1362404-T	rs1362404	0	1362404	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	(Lactobacillales order)	0.23	unit increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	18p11.22	18	10566407	NAPG	NAPG - LINC01887	ENSG00000134265	ENSG00000266604	NA	13643	45897	rs11877825-G	rs11877825	0	11877825	regulatory_region_variant	TRUE	NR	3e-11	10.522878745280337	(Erysipelotrichaceae family)	0.27	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	8p23.1	8	10834039	SOX7, PINX1	PINX1, PINX1, PINX1	NA	NA	ENSG00000284764, ENSG00000254093, ENSG00000258724	NA	NA	rs11986935-?	rs11986935	0	11986935	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.97	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.97
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	12q13.11	12	47876015	VDR	VDR	NA	NA	ENSG00000111424	NA	NA	rs7974353-?	rs7974353	0	7974353	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.75	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.75
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	20q13.12	20	44402226	HNF4A-AS1	HNF4A	NA	NA	ENSG00000101076	NA	NA	rs2071199-T	rs2071199	0	2071199	intron_variant	FALSE	NR	1e-8	8	(Bacilli class)	0.32	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	21q22.11	21	30827884	KRTAP8-1	KRTAP8-1 - KRTAP7-1	ENSG00000183640	ENSG00000274749	NA	14610	1155	rs34613612-C	rs34613612	0	34613612	intergenic_variant	TRUE	NR	6e-10	9.221848749616356	(Actinobacteria class)	0.25	unit increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	21q22.11	21	30827884	KRTAP8-1	KRTAP8-1 - KRTAP7-1	ENSG00000183640	ENSG00000274749	NA	14610	1155	rs34613612-C	rs34613612	0	34613612	intergenic_variant	TRUE	NR	6e-10	9.221848749616356	(Actinobacteria phylum)	0.25	unit increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	16p13.13	16	10948337	DEXI, CLEC16A	CLEC16A	NA	NA	ENSG00000038532	NA	NA	rs12931878-?	rs12931878	0	12931878	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.65	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.65
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	20q13.13	20	49838134	RNF114, SLC9A8, SPATA2	SLC9A8	NA	NA	ENSG00000197818	NA	NA	rs4809760-?	rs4809760	0	4809760	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	0.85	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.85
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (beta diversity)	1,812 European ancestry individuals	371 European ancestry individuals	21q22.13	21	37298033	intergenic	VPS26C - DYRK1A	ENSG00000157538	ENSG00000157540	NA	30114	67540	rs2835692-?	rs2835692	0	2835692	intergenic_variant	TRUE	NR	5e-8	7.301029995663981	NA	0.68	NR percent increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003876	Genome-wide genotyping array	NA	NA	0.68
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	5q31.3	5	142508341	SPRY4	SPRY4-AS1	NA	NA	ENSG00000231185	NA	NA	rs249733-T	rs249733	0	249733	intron_variant	FALSE	NR	5e-10	9.301029995663981	(OTU10032 unclassified Enterobacteriaceae)	0.65	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	2q14.3	2	128700224	HS6ST1	NA	NA	NA	NA	NA	NA	rs10928827-G	rs10928827	0	10928827	intergenic_variant	TRUE	NR	4e-9	8.397940008672037	(Lactobacillales order)	0.23	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	8q12.1	8	55677985	TGS1	NA - TMEM68	NA	ENSG00000167904	NA	NA	18439	rs13276516-A	rs13276516	0	13276516	intergenic_variant	TRUE	NR	6e-9	8.221848749616356	(OTU10032 unclassified Enterobacteriaceae)	0.61	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q26.1	15	90861558	NR	RN7SL363P - FURIN	ENSG00000241869	ENSG00000140564	NA	5351	7030	rs4932371-T	rs4932371	0	4932371	intergenic_variant	TRUE	NA	2e-13	12.698970004336019	NA	0.214	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12p13.33	12	309750	KDM5A	KDM5A	NA	NA	ENSG00000073614	NA	NA	rs4980877-C	rs4980877	0	4980877	intron_variant	FALSE	NA	3e-8	7.522878745280337	NA	0.162	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	9q34.2	9	133273983	ABO	ABO, ABO	NA	NA	ENSG00000175164, ENSG00000281879	NA	NA	rs507666-G	rs507666	0	507666	intron_variant	FALSE	NA	8e-6	5.096910013008056	NA	0.145	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q25.3	6	159275153	FNDC1, SOD2	FNDC1 - LINC02529	ENSG00000164694	ENSG00000234777	NA	3045	108269	rs516143-G	rs516143	0	516143	intergenic_variant	TRUE	NA	1e-16	16	NA	0.314	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p21.1	3	52695765	GLT8D1	GLT8D1	NA	NA	ENSG00000016864	NA	NA	rs528266117-C	rs528266117	1	377027069	non_coding_transcript_exon_variant	FALSE	NA	1e-8	8	NA	15.799	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q24.32	12	126546516	LOC100128554, LOC100507206	NDUFA5P6 - NA	ENSG00000256310	NA	NA	21890	NA	rs530280439-C	rs530280439	0	530280439	intergenic_variant	TRUE	NA	5e-9	8.301029995663981	NA	17.469	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p36.22	1	11836799	NR	CLCN6	NA	NA	ENSG00000011021	NA	NA	rs55892892-C	rs55892892	0	55892892	intron_variant	FALSE	NA	8e-20	19.096910013008056	NA	0.517	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q21.1	4	76444738	SHROOM3	SHROOM3	NA	NA	ENSG00000138771	NA	NA	rs55940751-C	rs55940751	0	55940751	intron_variant	FALSE	NA	8e-7	6.096910013008056	NA	0.129	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q21.2	7	91639626	FZD1, MTERF	NA - MTERF1	NA	ENSG00000127989	NA	NA	52382	rs560276033-GTA	rs560276033	1	34583398	intron_variant	TRUE	NA	2e-9	8.698970004336019	NA	0.429	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16q13	16	56294899	GNAO1	GNAO1	NA	NA	ENSG00000087258	NA	NA	rs56143613-A	rs56143613	0	56143613	intron_variant	FALSE	NA	2e-9	8.698970004336019	NA	0.282	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16q21	16	65231799	CDH11, LOC283867	LINC02126 - LINC00922	ENSG00000259847	ENSG00000261742	NA	55086	52697	rs56249585-C	rs56249585	0	56249585	intron_variant	TRUE	NA	6e-14	13.221848749616356	NA	0.337	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q22.1	4	88831125	FAM13A	FAM13A	NA	NA	ENSG00000138640	NA	NA	rs57400569-G	rs57400569	0	57400569	intron_variant	FALSE	NA	1e-11	11	NA	0.204	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	21q21.3	21	28751211	LINC00161, N6AMT1	U6 - NA	ENSG00000266435	NA	NA	7920	NA	rs57448815-A	rs57448815	0	57448815	intergenic_variant	TRUE	NA	6e-9	8.221848749616356	NA	0.227	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q23.2	11	113089378	NCAM1	NCAM1	NA	NA	ENSG00000149294	NA	NA	rs5794844-GT	rs5794844	0	5794844	intron_variant	FALSE	NA	3e-9	8.522878745280337	NA	0.268	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q25.3	10	113839323	NR	DCLRE1A	NA	NA	ENSG00000198924	NA	NA	rs59682205-T	rs59682205	0	59682205	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.545	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q13.32	20	59176062	SLMO2, ZNF831	ZNF831	NA	NA	ENSG00000124203	NA	NA	rs6015450-A	rs6015450	0	6015450	intron_variant	FALSE	NA	8e-6	5.096910013008056	NA	0.177	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p32.1	1	59197669	HSD52, MIR4711	FGGY-DT, LINC01358	NA	NA	ENSG00000224609, ENSG00000237352	NA	NA	rs60199046-A	rs60199046	0	60199046	intron_variant	FALSE	NA	1e-27	27	NA	0.313	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	20q13.12	20	44168718	JPH2	JPH2	NA	NA	ENSG00000149596	NA	NA	rs6031435-A	rs6031435	0	6031435	intron_variant	FALSE	NA	3e-11	10.522878745280337	NA	0.17	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	18q12.2	18	36709322	FHOD3	FHOD3	NA	NA	ENSG00000134775	NA	NA	rs61735998-G	rs61735998	0	61735998	missense_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.519	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007096	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr20:57738070-?	chr20:57738070	0	NA	NA	TRUE	NA	1e-6	6	NA	0.398	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	NA	NA	NA	GABRB1	NA	NA	NA	NA	NA	NA	chr4:47378386-?	chr4:47378386	0	NA	NA	TRUE	NA	4e-7	6.3979400086720375	NA	18.282	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q24.32	10	102834750	CYP17A1	CYP17A1	NA	NA	ENSG00000148795	NA	NA	rs1004467-A	rs1004467	0	1004467	non_coding_transcript_exon_variant	FALSE	NA	3e-41	40.52287874528034	NA	0.833	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q14.1	5	78541966	LHFPL2	LHFPL2	NA	NA	ENSG00000145685	NA	NA	rs10057188-G	rs10057188	0	10057188	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	0.182	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q21.13	8	81937217	SNX16, RALYL	LINC02235 - NA	ENSG00000254689	NA	NA	12869	NA	rs10103353-C	rs10103353	0	10103353	regulatory_region_variant	TRUE	NA	3e-6	5.522878745280337	NA	0.18	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p23.3	2	24907673	ADCY3	ADCY3	NA	NA	ENSG00000138031	NA	NA	rs10198275-A	rs10198275	0	10198275	intron_variant	FALSE	NA	8e-6	5.096910013008056	NA	0.171	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	5p15.31	5	8536741	SEMA5A	MIR4458HG - MTND6P2	ENSG00000247516	ENSG00000250389	NA	49811	81840	rs1666789-A	rs1666789	0	1666789	intron_variant	TRUE	NR	5e-8	7.301029995663981	(PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY_protocatechuate_degradation_II_(ortho-cleavage_pathway))	5.4516397	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.4516397	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	20q13.13	20	50275837	CEBPB	PELATON	NA	NA	ENSG00000224397	NA	NA	rs17789629-A	rs17789629	0	17789629	intron_variant	FALSE	NR	1e-8	8	(GO:0008484|MF|04|sulfuric ester hydrolase activity)	5.662547	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.662547	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	3q24	3	143495620	SLC9A9	SLC9A9	NA	NA	ENSG00000181804	NA	NA	rs10935496-A	rs10935496	0	10935496	intron_variant	FALSE	NR	3e-8	7.522878745280337	(GO:0015238|MF|03|drug transmembrane transporter activity)	5.527629	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.527629	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	3p24.1	3	26982961	NEK10	NA	NA	NA	NA	NA	NA	rs2166811-G	rs2166811	0	2166811	intergenic_variant	TRUE	NR	4e-8	7.3979400086720375	(GO:0016706|MF|04|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors)	5.5117273	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.5117273	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	5q35.1	5	172571935	AC027309.1	LINC01944 - NEURL1B	ENSG00000254299	ENSG00000214357	NA	12733	69328	rs56879175-C	rs56879175	0	56879175	regulatory_region_variant	TRUE	NR	5e-8	7.301029995663981	(GO:0003697|MF|06|single-stranded DNA binding)	5.4600735	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.4600735	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	3p22.1	3	41527300	ULK4	ULK4	NA	NA	ENSG00000168038	NA	NA	rs1353394-G	rs1353394	0	1353394	intron_variant	FALSE	NR	1e-8	8	(PWY-7282_4-amino-2-methyl-5-phosphomethylpyrimidine_biosynthesis_(yeast))	5.66631	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.66631	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	6p12.1	6	56344453	COL21A1	COL21A1	NA	NA	ENSG00000124749	NA	NA	rs9475677-A	rs9475677	0	9475677	intron_variant	FALSE	NR	2e-8	7.698970004336019	(PWY-6728_methylaspartate_cycle)	5.6379704	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.6379704	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	2q12.3	2	108326747	SULT1C2	SULT1C2P1	NA	NA	ENSG00000237223	NA	NA	rs17770672-A	rs17770672	0	17770672	intron_variant	FALSE	NR	2e-8	7.698970004336019	(PWY-5862_superpathway_of_demethylmenaquinol-9_biosynthesis)	5.612498	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.612498	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	1q21.3	1	151322585	PI4KB	PI4KB	NA	NA	ENSG00000143393	NA	NA	rs5022636-A	rs5022636	0	5022636	intron_variant	FALSE	NR	2e-8	7.698970004336019	(POLYAMINSYN3-PWY_superpathway_of_polyamine_biosynthesis_II)	5.5952206	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.5952206	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	1p36.32	1	4336479	LOC284661	NA - LINC01777	NA	ENSG00000235054	NA	NA	75548	rs199545687-C	rs199545687	0	199545687	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	(GO:0005874|CC|03|microtubule)	5.596856	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.596856	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	4p16.1	4	7583040	SORCS2	SORCS2	NA	NA	ENSG00000184985	NA	NA	rs10012347-T	rs10012347	0	10012347	intron_variant	FALSE	NR	3e-9	8.522878745280337	(PWY-6948_sitosterol_degradation_to_androstenedione)	5.925757	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.925757	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	5q21.3	5	105387215	NUDT12	NA - TENM2	NA	ENSG00000145934	NA	NA	61897584	rs76482840-A	rs76482840	0	76482840	intron_variant	TRUE	NR	3e-8	7.522878745280337	(PWY-3781_aerobic_respiration_I_(cytochrome_c))	5.567065	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.567065	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	5q34	5	168784249	SLIT3	SLIT3	NA	NA	ENSG00000184347	NA	NA	rs2163761-T	rs2163761	0	2163761	intron_variant	FALSE	NR	4e-9	8.397940008672037	(PWY-6948_sitosterol_degradation_to_androstenedione)	5.8900447	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.8900447	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	11q13.5	11	76588150	C11ORF30, LRRC32	EMSY - LINC02757	ENSG00000158636	ENSG00000255363	NA	35125	19703	rs2155219-T	rs2155219	0	2155219	intergenic_variant	TRUE	NR	1e-7	7	(GO:0007267|BP|03|cell-cell signaling)	5.277366	Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.277366	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	10q26.3	10	129140461	MGMT	NA	NA	NA	NA	NA	NA	rs1041530-C	rs1041530	0	1041530	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	(PWY-6395_superpathway_of_seleno-compound_metabolism)	5.5244126	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.5244126	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	17q12	17	34266646	CCL2, CCL7, CCL11	CCL2 - CCL7	ENSG00000108691	ENSG00000108688	NA	9443	3575	rs3091315-G	rs3091315	0	3091315	regulatory_region_variant	TRUE	NR	5e-7	6.301029995663981	(PWY-6654_phosphopantothenate_biosynthesis_III)	5.0421667	Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.0421667	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	11q13.5	11	76581531	C11ORF30, LRRC32	EMSY - LINC02757	ENSG00000158636	ENSG00000255363	NA	28506	26322	rs7110818-T	rs7110818	0	7110818	intergenic_variant	TRUE	NR	5e-7	6.301029995663981	(GO:0007267|BP|03|cell-cell signaling)	5.027987	Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.027987	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	8p11.21	8	42617131	SMIM19	SMIM19 - CHRNB3	ENSG00000176209	ENSG00000147432	NA	61936	80235	rs7016086-C	rs7016086	0	7016086	intergenic_variant	TRUE	NR	4e-8	7.3979400086720375	(PWY-5873_ubiquinol-7_biosynthesis_(eukaryotic))	5.47637	NR Z-score decrease	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.47637	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	2p11.2	2	83789964	SUCLG1	NA	NA	NA	NA	NA	NA	rs2084597-T	rs2084597	0	2084597	regulatory_region_variant	TRUE	NR	5e-8	7.301029995663981	(PWY-6731_starch_degradation_III)	5.4584117	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.4584117	NA
2017-03-31	27694959	Bonder MJ	2016-10-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27694959	The effect of host genetics on the gut microbiome.	Gut microbiota (functional units)	984 European ancestry individuals	530 European ancestry individuals	3q27.3	3	186374770	DGKG	DGKG - LINC02020	ENSG00000058866	ENSG00000234548	NA	12536	64469	rs35598536-A	rs35598536	0	35598536	regulatory_region_variant	TRUE	NR	5e-8	7.301029995663981	(ARO-PWY_chorismate_biosynthesis_I)	5.45223	NR Z-score increase	Illumina [8100000] (imputed)	N	gut microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874	GCST003854	Genome-wide genotyping array	NA	5.45223	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	3p26.3	3	1450365	CNTN6	CNTN6 - NA	ENSG00000134115	NA	NA	46148	NA	rs11915634-T	rs11915634	0	11915634	intergenic_variant	TRUE	NR	3e-10	9.522878745280337	(Marinilabiliaceae family)	1.3	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	3p26.3	3	1450365	CNTN6	CNTN6 - NA	ENSG00000134115	NA	NA	46148	NA	rs11915634-T	rs11915634	0	11915634	intergenic_variant	TRUE	NR	3e-10	9.522878745280337	(Unclassified Marinilabiliaceae)	1.3	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	3p22.2	3	38247760	SLC22A13, MYD88, DLEC1, ACAA1, OXSR1	OXSR1	NA	NA	ENSG00000172939	NA	NA	rs3925158-C	rs3925158	0	3925158	intron_variant	FALSE	NR	6e-9	8.221848749616356	(OTU10032 unclassified Enterobacteriaceae Species-level OTU)	1	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	3p14.3	3	58063912	FLNB	FLNB	NA	NA	ENSG00000136068	NA	NA	rs13096731-A	rs13096731	0	13096731	intron_variant	FALSE	NR	3e-8	7.522878745280337	(EscherichiaShigella)	0.43	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	3q11.2	3	95804156	LINC00879	NA	NA	NA	NA	NA	NA	rs59042687-T	rs59042687	0	59042687	intergenic_variant	TRUE	NR	6e-9	8.221848749616356	(Lactobacillales order)	0.23	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	3q12.1	3	99206060	LINC00973	NA - ACTG1P13	NA	ENSG00000241305	NA	NA	9164	rs9831278-C	rs9831278	0	9831278	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	(Unclassified Marinilabiliaceae)	1.16	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	3q12.1	3	99206060	LINC00973	NA - ACTG1P13	NA	ENSG00000241305	NA	NA	9164	rs9831278-C	rs9831278	0	9831278	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	(Marinilabiliaceae family)	1.16	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	3q26.1	3	163319659	LINC01192	LINC01192	NA	NA	ENSG00000241369	NA	NA	rs62295801-G	rs62295801	0	62295801	intron_variant	FALSE	NR	5e-10	9.301029995663981	(Lactobacillales order)	0.27	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	3q27.2	3	186012260	LOC344887	NMRAL2P - ETV5	ENSG00000171658	ENSG00000244405	NA	31388	34054	rs7646786-T	rs7646786	0	7646786	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	(Bacilli class)	0.22	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	4p16.1	4	9816492	SLC2A9, DRD5	SLC2A9	NA	NA	ENSG00000109667	NA	NA	rs7656342-A	rs7656342	0	7656342	intron_variant	FALSE	NR	3e-9	8.522878745280337	(Unclassified Porphyromonadaceae)	0.39	unit increase	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	4q21.1	4	76541625	SHROOM3	SHROOM3	NA	NA	ENSG00000138771	NA	NA	rs11724031-G	rs11724031	0	11724031	intron_variant	FALSE	NR	2e-10	9.698970004336019	(Marinilabiliaceae family)	0.97	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	4q21.1	4	76541625	SHROOM3	SHROOM3	NA	NA	ENSG00000138771	NA	NA	rs11724031-G	rs11724031	0	11724031	intron_variant	FALSE	NR	2e-10	9.698970004336019	(Unclassified Marinilabiliaceae)	0.97	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	4q28.3	4	130578414	RP11-422J15.1	GAPDHP56 - NA	ENSG00000249018	NA	NA	74070	NA	rs17421787-C	rs17421787	0	17421787	intergenic_variant	TRUE	NR	4e-8	7.3979400086720375	(Erysipelotrichaceae family)	0.3	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	4q28.3	4	130578414	RP11-422J15.1	GAPDHP56 - NA	ENSG00000249018	NA	NA	74070	NA	rs17421787-C	rs17421787	0	17421787	intergenic_variant	TRUE	NR	4e-8	7.3979400086720375	(Erysipelotrichales order)	0.3	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	4q28.3	4	130578414	RP11-422J15.1	GAPDHP56 - NA	ENSG00000249018	NA	NA	74070	NA	rs17421787-C	rs17421787	0	17421787	intergenic_variant	TRUE	NR	4e-8	7.3979400086720375	(Erysipelotrichia class)	0.3	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-04-04	27723756	Wang J	2016-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27723756	Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.	Gut microbiota (bacterial taxa)	1,812 European ancestry individuals	NA	5q12.3	5	67230381	CD180	CD180 - NA	ENSG00000134061	NA	NA	33582	NA	rs9291879-C	rs9291879	0	9291879	intergenic_variant	TRUE	NR	4e-9	8.397940008672037	(Unclassified Porphyromonadaceae)	0.58	unit decrease	Affymetrix, Illumina [6344846] (imputed)	N	gut microbiome measurement, taxonomic microbiome measurement	http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883	GCST003875	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	13q12.3	13	30172832	UBL3, KATNAL1	LINC00385 - KATNAL1	ENSG00000232643	ENSG00000102781	NA	12240	29798	rs9314998-?	rs9314998	0	9314998	regulatory_region_variant	TRUE	NR	2e-9	8.698970004336019	NA	1.146	[1.097-1.198]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.146	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	12q13.12	12	50751299	DIP2B, ATF1	DIP2B - ATF1	ENSG00000066084	ENSG00000123268	NA	2642	12411	rs7974517-?	rs7974517	0	7974517	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	NA	1.1520737	[1.10-1.21]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1520737	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	6p21.1	6	44699178	CDC5L, SUPT3H	NA	NA	NA	NA	NA	NA	rs227808-?	rs227808	0	227808	regulatory_region_variant	TRUE	NR	3e-9	8.522878745280337	NA	1.1820331	[1.12-1.25]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1820331	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	3q23	3	139313491	PRR23C, MRPS22	MRPS22	NA	NA	ENSG00000175110	NA	NA	rs7642536-?	rs7642536	0	7642536	intron_variant	FALSE	NR	3e-9	8.522878745280337	NA	1.2391574	[1.15-1.33]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.2391574	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	7p12.3	7	46904161	IGFBP3, TNS3	AHR - NA	ENSG00000106546	NA	NA	29558009	NA	rs12702271-?	rs12702271	0	12702271	intron_variant	TRUE	NR	3e-9	8.522878745280337	NA	1.171	[1.111-1.233]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.171	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	4q21.21	4	80285223	FGF5	FGF5	NA	NA	ENSG00000138675	NA	NA	rs4690116-?	rs4690116	0	4690116	intron_variant	FALSE	NR	6e-9	8.221848749616356	NA	1.1415524	[1.09-1.19]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1415524	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	16p13.12	16	14298066	MKL2, PARN	Y_RNA - MIR193BHG	ENSG00000199964	ENSG00000262454	NA	22466	3323	rs246180-?	rs246180	0	246180	intergenic_variant	TRUE	NR	8e-9	8.096910013008056	NA	1.152	[1.098-1.209]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.152	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	2q13	2	108897145	EDAR	EDAR	NA	NA	ENSG00000135960	NA	NA	rs3827760-?	rs3827760	0	3827760	missense_variant	FALSE	NR	1e-8	8	NA	2.2371366	[1.68-2.99]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	2.2371366	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	2p21	2	43363760	THADA	THADA	NA	NA	ENSG00000115970	NA	NA	rs11694173-?	rs11694173	0	11694173	intron_variant	FALSE	NR	2e-8	7.698970004336019	NA	1.1737089	[1.11-1.24]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1737089	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	12q24.33	12	130078818	TMEM132D, FZD10	LINC02419 - FZD10-AS1	ENSG00000256906	ENSG00000250208	NA	6133	65497	rs76972608-?	rs76972608	0	76972608	intergenic_variant	TRUE	NR	4e-8	7.3979400086720375	NA	1.1990408	[1.12-1.28]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1990408	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	2q31.1	2	176833154	MTX2, HNRNPA3	LINC01117 - RNU6-187P	ENSG00000224577	ENSG00000206866	NA	13974	96831	rs1819008-?	rs1819008	0	1819008	intron_variant	TRUE	NR	4e-8	7.3979400086720375	NA	1.1312217	[1.08-1.18]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.1312217	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	Xp22.31	X	8912639	FAM9A, FAM9B	ANAPC15P1 - NOLC1P1	ENSG00000231619	ENSG00000225271	NA	55580	67786	rs5933688-?	rs5933688	0	5933688	intron_variant	TRUE	NR	4e-8	7.3979400086720375	NA	1.102	[1.065-1.141]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.102	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Male-pattern baldness	9,009 European ancestry cases, 8,491 European ancestry controls	NA	2q31.1	2	173740905	CDCA7, SP3	NA	NA	NA	NA	NA	NA	rs13405699-?	rs13405699	0	13405699	intergenic_variant	TRUE	NR	5e-8	7.301029995663981	NA	1.4880953	[1.29-1.72]	Illumina [13436641] (imputed)	N	androgenetic alopecia	http://www.ebi.ac.uk/efo/EFO_0004191	GCST003983	Genome-wide genotyping array	NA	1.4880953	NA
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	2p24.1	2	20982585	APOB	NA - APOB	NA	ENSG00000084674	NA	NA	18844	rs10172650-A	rs10172650	0	10172650	intergenic_variant	TRUE	0.13	4e-14	13.397940008672037	(Asian initial, BMI unadjusted)	0.092	[0.068-0.116] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.13	NA	0.092
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	13q13.1	13	32379251	BRCA2	BRCA2	NA	NA	ENSG00000139618	NA	NA	rs4942486-T	rs4942486	0	4942486	intron_variant	FALSE	0.462	5e-14	13.301029995663981	(Trans-ethnic initial)	0.0243	[0.017-0.032] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.462	NA	0.0243
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	7p15.3	7	21567734	DNAH11	DNAH11	NA	NA	ENSG00000105877	NA	NA	rs12670798-T	rs12670798	0	12670798	intron_variant	FALSE	0.776	2e-12	11.698970004336019	(Trans-ethnic initial)	0.0344	[0.026-0.043] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.776	NA	0.0344
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	5q23.2	5	123519722	CSNK1G3	CSNK1G3	NA	NA	ENSG00000151292	NA	NA	rs4530754-A	rs4530754	0	4530754	intron_variant	FALSE	0.582	3e-12	11.522878745280337	(Trans-ethnic initial)	0.0275	[0.02-0.035] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.582	NA	0.0275
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	1p36.11	1	26811902	PIGV, NROB2	PIGV - RN7SL165P	ENSG00000060642	ENSG00000241188	NA	11243	2920	rs12748152-T	rs12748152	0	12748152	regulatory_region_variant	TRUE	0.0712	3e-12	11.522878745280337	(Trans-ethnic initial)	0.0499	[0.037-0.063] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.0712	NA	0.0499
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	20p12.1	20	12982070	SPTLC3	LINC01723	NA	NA	ENSG00000234265	NA	NA	rs364585-A	rs364585	0	364585	intron_variant	FALSE	0.367	4e-11	10.397940008672037	(Trans-ethnic initial)	0.0249	[0.017-0.032] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.367	NA	0.0249
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	8q11.23	8	54509054	SOX17	TRMT112P7 - RP1	ENSG00000270275	ENSG00000104237	NA	29091	368	rs10102164-A	rs10102164	0	10102164	regulatory_region_variant	TRUE	0.174	8e-11	10.096910013008056	(Trans-ethnic initial)	0.0316	[0.023-0.04] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.174	NA	0.0316
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	2p15	2	62922422	EHBP1	EHBP1	NA	NA	ENSG00000115504	NA	NA	rs2710642-A	rs2710642	0	2710642	intron_variant	FALSE	0.619	2e-10	9.698970004336019	(Trans-ethnic initial)	0.0239	[0.016-0.031] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.619	NA	0.0239
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	20p12.1	20	17865277	SNX5	NA - RNU6-192P	NA	ENSG00000212555	NA	NA	38485	rs2328223-A	rs2328223	0	2328223	intergenic_variant	TRUE	0.751	2e-10	9.698970004336019	(Trans-ethnic initial)	0.0299	[0.02-0.04] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.751	NA	0.0299
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	17p13.1	17	7188331	DLG4	DLG4	NA	NA	ENSG00000132535	NA	NA	rs314253-T	rs314253	0	314253	3_prime_UTR_variant	FALSE	0.665	4e-10	9.397940008672037	(Trans-ethnic initial)	0.0242	[0.017-0.032] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.665	NA	0.0242
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	9p24.2	9	2640759	VLDLR	VLDLR	NA	NA	ENSG00000147852	NA	NA	rs3780181-A	rs3780181	0	3780181	non_coding_transcript_exon_variant	FALSE	0.947	5e-10	9.301029995663981	(Trans-ethnic initial)	0.0445	[0.03-0.059] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.947	NA	0.0445
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	11q12.2	11	61781553	FADS1, FADS2, FADS3	MYRF, TMEM258	NA	NA	ENSG00000124920, ENSG00000134825	NA	NA	rs174533-A	rs174533	0	174533	intron_variant	FALSE	0.38	1e-9	9	(Asian initial, BMI unadjusted)	0.062	[0.042-0.082] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.38	NA	0.062
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	3q22.1	3	132490359	ACAD11	DNAJC13	NA	NA	ENSG00000138246	NA	NA	rs17345563-A	rs17345563	0	17345563	intron_variant	FALSE	0.871	1e-9	9	(Trans-ethnic initial)	0.0358	[0.025-0.047] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.871	NA	0.0358
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	6q22.1	6	116031587	FRK	FRK	NA	NA	ENSG00000111816	NA	NA	rs6909746-T	rs6909746	0	6909746	intron_variant	FALSE	0.392	2e-9	8.698970004336019	(Trans-ethnic initial)	0.0263	[0.019-0.034] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.392	NA	0.0263
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	9q34.2	9	133278724	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	2700	23746	rs579459-T	rs579459	0	579459	intergenic_variant	TRUE	0.65	2e-9	8.698970004336019	(Asian initial, BMI unadjusted)	0.057	[0.039-0.075] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.65	NA	0.057
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	2q35	2	215439661	FN1	FN1 - NA	ENSG00000115414	NA	NA	3588	NA	rs1250229-T	rs1250229	0	1250229	intergenic_variant	TRUE	0.211	2e-9	8.698970004336019	(Trans-ethnic initial)	0.0243	[0.016-0.033] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.211	NA	0.0243
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	22q12.2	22	29982714	MTMR3	MTMR3	NA	NA	ENSG00000100330	NA	NA	rs5763662-T	rs5763662	0	5763662	non_coding_transcript_exon_variant	FALSE	0.0251	3e-9	8.522878745280337	(Trans-ethnic initial)	0.0767	[0.053-0.1] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.0251	NA	0.0767
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	13q13.1	13	32355095	BRCA2	BRCA2	NA	NA	ENSG00000139618	NA	NA	rs1799955-A	rs1799955	0	1799955	synonymous_variant	FALSE	0.63	3e-9	8.522878745280337	(Asian initial, BMI unadjusted)	0.052	[0.034-0.07] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.63	NA	0.052
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	4p16.3	4	3433158	LRPAP1	RGS12	NA	NA	ENSG00000159788	NA	NA	rs6818397-T	rs6818397	0	6818397	intron_variant	FALSE	0.413	3e-9	8.522878745280337	(Trans-ethnic initial)	0.0224	[0.015-0.03] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.413	NA	0.0224
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	8q24.13	8	125476008	TRIB1	TRIB1 - NA	ENSG00000173334	NA	NA	37605	NA	rs2980869-T	rs2980869	0	2980869	intron_variant	TRUE	0.56	4e-9	8.397940008672037	(Asian initial, BMI unadjusted)	0.049	[0.033-0.065] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.56	NA	0.049
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	2q14.2	2	120551912	LOC84931	LINC01101 - Y_RNA	ENSG00000280409	ENSG00000199964	NA	85694	99361	rs2030746-T	rs2030746	0	2030746	intergenic_variant	TRUE	0.398	8e-9	8.096910013008056	(Trans-ethnic initial)	0.0214	[0.014-0.029] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.398	NA	0.0214
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	1p32.3	1	55063514	PCSK9	PCSK9	NA	NA	ENSG00000169174	NA	NA	rs505151-A	rs505151	0	505151	missense_variant	FALSE	0.94	9e-9	8.045757490560675	(Asian initial, BMI unadjusted)	0.107	[0.072-0.142] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.94	NA	0.107
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	6p12.2	6	52587787	TRAM2	TRAM2-AS1	NA	NA	ENSG00000225791	NA	NA	rs2239620-A	rs2239620	0	2239620	intron_variant	FALSE	0.6293	2e-8	7.698970004336019	(Trans-ethnic initial)	0.0272	[0.017-0.038] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.6293	NA	0.0272
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	3q21.1	3	122426477	KPNA1	WDR5B-DT, KPNA1	NA	NA	ENSG00000272758, ENSG00000114030	NA	NA	rs3762637-T	rs3762637	0	3762637	3_prime_UTR_variant	FALSE	0.1438	3e-8	7.522878745280337	(Trans-ethnic initial)	0.0234	[0.013-0.033] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.1438	NA	0.0234
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	2q37.1	2	233770738	UGT1A1	UGT1A8, UGT1A9, UGT1A4, UGT1A7, UGT1A10, UGT1A6, UGT1A5, UGT1A1, UGT1A3	NA	NA	ENSG00000242366, ENSG00000241119, ENSG00000244474, ENSG00000244122, ENSG00000242515, ENSG00000167165, ENSG00000288705, ENSG00000241635, ENSG00000288702	NA	NA	rs11563251-T	rs11563251	0	11563251	3_prime_UTR_variant	FALSE	0.125	4e-8	7.3979400086720375	(Trans-ethnic initial)	0.0345	[0.022-0.047] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.125	NA	0.0345
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17p11.2	17	16273569	PIGL	PIGL	NA	NA	ENSG00000108474	NA	NA	rs2014604-C	rs2014604	0	2014604	intron_variant	FALSE	0.5209	3e-11	10.522878745280337	NA	0.02362921	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5209	NA	0.02362921
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17p11.2	17	16948873	TNFRSF13B	TNFRSF13B	NA	NA	ENSG00000240505	NA	NA	rs34557412-G	rs34557412	0	34557412	missense_variant	FALSE	0.0075	1e-14	14	NA	0.168474	[0.13-0.21] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0075	NA	0.168474
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17q11.2	17	27521170	KSR1	KSR1	NA	NA	ENSG00000141068	NA	NA	rs1105527-T	rs1105527	0	1105527	intron_variant	FALSE	0.5876	5e-11	10.301029995663981	NA	0.02368987	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5876	NA	0.02368987
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17q12	17	34219137	intergenic	LINC01989 - CCL2	ENSG00000261156	ENSG00000108691	NA	23200	36081	rs9906695-T	rs9906695	0	9906695	regulatory_region_variant	TRUE	0.2221	3e-11	10.522878745280337	NA	0.02865212	[0.02-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2221	NA	0.02865212
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17q21.1	17	39912823	GSDMB	GSDMB	NA	NA	ENSG00000073605	NA	NA	rs921650-A	rs921650	0	921650	intron_variant	FALSE	0.4829	2e-31	30.69897000433602	NA	0.04151507	[0.035-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.4829	NA	0.04151507
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17q21.1	17	40009750	RP11-387H17.6	PSMD3 - CSF3	ENSG00000108344	ENSG00000108342	NA	11791	5611	rs4795419-A	rs4795419	0	4795419	intergenic_variant	TRUE	0.3905	5e-81	80.30102999566398	NA	0.0693653	[0.062-0.076] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3905	NA	0.0693653
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17q22	17	58281068	MPO	MPO - TSPOAP1	ENSG00000005381	ENSG00000005379	NA	133	20160	rs34097845-T	rs34097845	0	34097845	intergenic_variant	TRUE	0.0578	4e-63	62.39794000867204	NA	0.1320404	[0.12-0.15] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0578	NA	0.1320404
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17q22	17	58313062	BZRAP1	TSPOAP1	NA	NA	ENSG00000005379	NA	NA	rs2680706-G	rs2680706	0	2680706	intron_variant	FALSE	0.2766	1e-17	17	NA	0.03417565	[0.026-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2766	NA	0.03417565
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17q23.1	17	59808348	VMP1	VMP1	NA	NA	ENSG00000062716	NA	NA	rs7212590-T	rs7212590	0	7212590	intron_variant	FALSE	0.0797	4e-19	18.397940008672037	NA	0.05853947	[0.046-0.071] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0797	NA	0.05853947
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17q25.1	17	74758785	SLC9A3R1	SLC9A3R1	NA	NA	ENSG00000109062	NA	NA	rs12603194-A	rs12603194	0	12603194	intron_variant	FALSE	0.4974	7e-10	9.154901959985743	NA	0.02250925	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.4974	NA	0.02250925
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17q25.3	17	82284274	intergenic	CSNK1D - LINC01970	ENSG00000141551	ENSG00000265692	NA	10543	5772	rs111231601-C	rs111231601	0	111231601	intergenic_variant	TRUE	0.0272	8e-9	8.096910013008056	NA	0.07093482	[0.047-0.095] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0272	NA	0.07093482
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17q25.3	17	83115144	intergenic	METRNL - NA	ENSG00000275031	NA	NA	20022	NA	rs77572283-C	rs77572283	0	77572283	intergenic_variant	TRUE	0.459	5e-43	42.30102999566398	NA	0.05553528	[0.048-0.063] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.459	NA	0.05553528
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	18q21.33	18	63253621	BCL2	BCL2	NA	NA	ENSG00000171791	NA	NA	rs17758695-T	rs17758695	0	17758695	intron_variant	FALSE	0.0299	7e-13	12.154901959985743	NA	0.07556674	[0.055-0.096] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0299	NA	0.07556674
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	18q23	18	76360290	ZNF516	ZNF516	NA	NA	ENSG00000101493	NA	NA	rs72973711-T	rs72973711	0	72973711	3_prime_UTR_variant	FALSE	0.0667	3e-18	17.522878745280337	NA	0.062905	[0.049-0.077] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0667	NA	0.062905
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19p13.3	19	837174	PRTN3	AZU1 - PRTN3	ENSG00000172232	ENSG00000196415	NA	5156	3825	rs138303849-C	rs138303849	0	138303849	intergenic_variant	TRUE	0.2535	6e-9	8.221848749616356	NA	0.02442823	[0.016-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2535	NA	0.02442823
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19p13.3	19	3176172	S1PR4	S1PR4	NA	NA	ENSG00000125910	NA	NA	rs3760960-G	rs3760960	0	3760960	intron_variant	FALSE	0.1237	2e-9	8.698970004336019	NA	0.03247049	[0.022-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1237	NA	0.03247049
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19p13.3	19	5038906	KDM4B	KDM4B	NA	NA	ENSG00000127663	NA	NA	rs10426930-A	rs10426930	0	10426930	intron_variant	FALSE	0.3363	3e-9	8.522878745280337	NA	0.02226901	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3363	NA	0.02226901
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19p13.3	19	6668961	TNFSF14	TNFSF14	NA	NA	ENSG00000125735	NA	NA	rs1077667-T	rs1077667	0	1077667	intron_variant	FALSE	0.2085	5e-11	10.301029995663981	NA	0.02873288	[0.02-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2085	NA	0.02873288
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19p13.13	19	13093600	NFIX	NFIX	NA	NA	ENSG00000008441	NA	NA	rs144412371-G	rs144412371	0	144412371	intron_variant	FALSE	0.0388	2e-9	8.698970004336019	NA	0.05671791	[0.038-0.075] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0388	NA	0.05671791
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19p13.11	19	16417023	EPS15L1	EPS15L1	NA	NA	ENSG00000127527	NA	NA	rs4808047-C	rs4808047	0	4808047	intron_variant	FALSE	0.1549	4e-13	12.397940008672037	NA	0.03563354	[0.026-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1549	NA	0.03563354
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19p13.11	19	18005335	ARRDC2	ARRDC2	NA	NA	ENSG00000105643	NA	NA	rs35928002-G	rs35928002	0	35928002	intron_variant	FALSE	0.307	1e-14	14	NA	0.03055804	[0.023-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.307	NA	0.03055804
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19p13.11	19	18287818	RPL39P38	RPL39P38 - LSM4	ENSG00000241464	ENSG00000130520	NA	2323	18418	rs11086102-C	rs11086102	0	11086102	regulatory_region_variant	TRUE	0.6319	1e-26	26	NA	0.03966003	[0.032-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.6319	NA	0.03966003
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19p13.11	19	18402008	LRRC25	LRRC25 - SSBP4	ENSG00000175489	ENSG00000130511	NA	4386	16856	rs5827412-T	rs5827412	0	5827412	regulatory_region_variant	TRUE	0.4122	1e-27	27	NA	0.03952068	[0.032-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.4122	NA	0.03952068
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19q13.11	19	33260946	intergenic	SLC7A10 - CEBPA	ENSG00000130876	ENSG00000245848	NA	35096	38988	rs12151289-C	rs12151289	0	12151289	intergenic_variant	TRUE	0.0316	8e-19	18.096910013008056	NA	0.09254278	[0.072-0.113] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0316	NA	0.09254278
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	19q13.11	19	33267442	intergenic	SLC7A10 - CEBPA	ENSG00000130876	ENSG00000245848	NA	41592	32492	rs10412449-A	rs10412449	0	10412449	intergenic_variant	TRUE	0.4296	3e-9	8.522878745280337	NA	0.02145637	[0.014-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.4296	NA	0.02145637
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	11q23.3	11	116791863	APOA1, APOC3, APOA4, APOA5	APOA5	NA	NA	ENSG00000110243	NA	NA	rs651821-T	rs651821	0	651821	5_prime_UTR_variant	FALSE	0.72	9e-47	46.045757490560675	(BMI unadjusted)	0.187	[0.16-0.21] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.72	NA	0.187
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	8p21.3	8	19987865	LPL	LPL - NA	ENSG00000175445	NA	NA	20606	NA	rs7841189-T	rs7841189	0	7841189	TF_binding_site_variant	TRUE	0.1	2e-30	29.69897000433602	(BMI unadjusted)	0.172	[0.14-0.2] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.1	NA	0.172
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237	NA	14548	2511	rs3764261-A	rs3764261	0	3764261	regulatory_region_variant	TRUE	0.16	1e-29	29	(BMI unadjusted)	0.232	[0.19-0.27] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.16	NA	0.232
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	8p21.3	8	20028215	MET	LPL - RPL30P9	ENSG00000175445	ENSG00000242709	NA	60956	85128	rs11984636-T	rs11984636	0	11984636	intergenic_variant	TRUE	0.9	6e-27	26.221848749616356	(BMI unadjusted)	0.175	[0.14-0.21] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.9	NA	0.175
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	15q21.3	15	58401821	LIPC	ALDH1A2	NA	NA	ENSG00000128918	NA	NA	rs16940212-T	rs16940212	0	16940212	intron_variant	FALSE	0.3	1e-25	25	(BMI unadjusted)	0.102	[0.082-0.122] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.3	NA	0.102
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	9q31.1	9	104902020	ABCA1	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs1883025-T	rs1883025	0	1883025	intron_variant	FALSE	0.26	2e-18	17.69897000433602	(BMI unadjusted)	0.091	[0.071-0.111] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.26	NA	0.091
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	18q21.1	18	49592553	LIPG	LIPG	NA	NA	ENSG00000101670	NA	NA	rs3786247-T	rs3786247	0	3786247	3_prime_UTR_variant	FALSE	0.6	5e-15	14.301029995663981	(BMI unadjusted)	0.106	[0.081-0.131] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.6	NA	0.106
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	19q13.32	19	44919689	APOE, APOC1, APOC2	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855	NA	340	7115	rs4420638-A	rs4420638	0	4420638	regulatory_region_variant	TRUE	0.89	5e-12	11.301029995663981	(BMI unadjusted)	0.109	[0.078-0.14] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.89	NA	0.109
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	19p13.2	19	11230353	ANGPTL8	DOCK6	NA	NA	ENSG00000130158	NA	NA	rs1865063-T	rs1865063	0	1865063	intron_variant	FALSE	0.26	6e-12	11.221848749616356	(BMI adjusted)	0.0632	[0.046-0.08] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.26	NA	0.0632
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	6p21.1	6	43791136	VEGFA	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	4649	53742	rs6905288-A	rs6905288	0	6905288	regulatory_region_variant	TRUE	0.75	1e-11	11	(BMI adjusted)	0.0446	[0.031-0.059] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.75	NA	0.0446
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	16q22.1	16	67943479	LCAT	SLC12A4, LCAT	NA	NA	ENSG00000124067, ENSG00000213398	NA	NA	rs1109166-T	rs1109166	0	1109166	5_prime_UTR_variant	FALSE	0.87	4e-10	9.397940008672037	(BMI unadjusted)	0.086	[0.059-0.113] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.87	NA	0.086
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	12q24.31	12	123290580	ZNF664, SBNO1	SBNO1	NA	NA	ENSG00000139697	NA	NA	rs10773003-A	rs10773003	0	10773003	3_prime_UTR_variant	FALSE	0.31	6e-10	9.221848749616356	(BMI adjusted)	0.03	[0.02-0.04] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.31	NA	0.03
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	12q24.13	12	112379979	HECTD4	HECTD4	NA	NA	ENSG00000173064	NA	NA	rs11066280-A	rs11066280	0	11066280	intron_variant	FALSE	0.21	4e-9	8.397940008672037	(BMI unadjusted)	0.073	[0.048-0.098] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.21	NA	0.073
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	12q24.11	12	110948323	MYL2	LINC01405	NA	NA	ENSG00000185847	NA	NA	rs2188380-T	rs2188380	0	2188380	intron_variant	FALSE	0.82	8e-9	8.096910013008056	(BMI adjusted)	0.071	[0.046-0.096] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.82	NA	0.071
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	20q13.12	20	45948343	PLTP	PCIF1 - ZNF335	ENSG00000100982	ENSG00000198026	NA	320	317	rs6130975-A	rs6130975	0	6130975	regulatory_region_variant	TRUE	0.06	2e-8	7.698970004336019	(BMI unadjusted)	0.116	[0.077-0.155] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.06	NA	0.116
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	4q21.3	4	87061724	KLHL8	AFF1	NA	NA	ENSG00000172493	NA	NA	rs7660883-C	rs7660883	0	7660883	intron_variant	FALSE	0.58	5e-8	7.301029995663981	(BMI adjusted)	0.048	[0.03-0.066] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.58	NA	0.048
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	22q11.21	22	21619030	UBE2L3	UBE2L3	NA	NA	ENSG00000185651	NA	NA	rs4821116-T	rs4821116	0	4821116	intron_variant	FALSE	0.39	3e-6	5.522878745280337	(BMI unadjusted)	0.044	[0.026-0.062] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.39	NA	0.044
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	25,169 East Asian ancestry individuals	45,953 East Asian ancestry individuals	12p13.31	12	7498542	CD163	CD163	NA	NA	ENSG00000177575	NA	NA	rs10743940-A	rs10743940	0	10743940	intron_variant	FALSE	0.29	5e-6	5.301029995663981	(BMI unadjusted)	0.045	[0.025-0.065] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004234	Genome-wide genotyping array	0.29	NA	0.045
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	1q43	1	236584261	HEATR1	HEATR1	NA	NA	ENSG00000119285	NA	NA	rs150174091-G	rs150174091	0	150174091	intron_variant	FALSE	0.999	5e-6	5.301029995663981	(AA)	0.262	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	13q21.31	13	63474356	Intergenic	NA	NA	NA	NA	NA	NA	rs185603859-G	rs185603859	0	185603859	intron_variant	TRUE	0.999	5e-6	5.301029995663981	(AA)	0.229	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	12q14.3	12	65862615	AK128707	HMGA2, HMGA2-AS1	NA	NA	ENSG00000149948, ENSG00000197301	NA	NA	rs11175944-C	rs11175944	0	11175944	intron_variant	FALSE	0.312	5e-6	5.301029995663981	(AA)	0.016	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.312	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	6q26	6	162415192	PARK2	PRKN	NA	NA	ENSG00000185345	NA	NA	rs56681491-G	rs56681491	0	56681491	intron_variant	FALSE	0.695	5e-6	5.301029995663981	(AA)	0.016	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.695	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4p16.3	4	2737648	Intergenic	FAM193A - TNIP2	ENSG00000125386	ENSG00000168884	NA	5075	4000	rs180919520-C	rs180919520	0	180919520	intergenic_variant	TRUE	0.997	5e-6	5.301029995663981	(AA)	0.218	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.997	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	6q26	6	162415180	PARK2	PRKN	NA	NA	ENSG00000185345	NA	NA	rs60338266-A	rs60338266	0	60338266	intron_variant	FALSE	0.695	5e-6	5.301029995663981	(AA)	0.016	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.695	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97714221	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs7658560-T	rs7658560	0	7658560	intron_variant	FALSE	0.626	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.626	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97714434	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs7658798-G	rs7658798	0	7658798	intron_variant	FALSE	0.626	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.626	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97625522	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs7676966-C	rs7676966	0	7676966	intron_variant	FALSE	0.562	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.562	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q32.3	4	165751684	Intergenic	LINC01179	NA	NA	ENSG00000249500	NA	NA	rs2859815-C	rs2859815	0	2859815	intron_variant	FALSE	0.826	5e-6	5.301029995663981	(AA)	0.021	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.826	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	7q36.1	7	152052174	GALNT11	GALNT11	NA	NA	ENSG00000178234	NA	NA	rs149069622-G	rs149069622	0	149069622	intron_variant	FALSE	0.999	5e-6	5.301029995663981	(AA)	0.383	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	7q11.22	7	71157441	WBSCR17	GALNT17	NA	NA	ENSG00000185274	NA	NA	rs182033693-C	rs182033693	0	182033693	intron_variant	FALSE	1.0	5e-6	5.301029995663981	(AA)	0.54	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97590469	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs61154600-T	rs61154600	0	61154600	intron_variant	FALSE	0.56	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.56	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97590475	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs58276078-C	rs58276078	0	58276078	intron_variant	FALSE	0.56	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.56	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97589677	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs56880249-C	rs56880249	0	56880249	intron_variant	FALSE	0.56	5e-6	5.301029995663981	(AA)	0.015	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.56	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	8p12	8	36022514	Intergenic	NA	NA	NA	NA	NA	NA	rs183529902-C	rs183529902	0	183529902	intron_variant	TRUE	0.998	5e-6	5.301029995663981	(AA)	0.26	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.998	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78606661	CHRNA3	CHRNA3	NA	NA	ENSG00000080644	NA	NA	rs56077333-A	rs56077333	0	56077333	intron_variant	FALSE	0.82	6e-6	5.221848749616356	(AA)	0.02	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.82	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	6q22.33	6	127890661	THEMIS	THEMIS, THEMIS	NA	NA	ENSG00000172673, ENSG00000275122	NA	NA	rs192087058-A	rs192087058	0	192087058	intron_variant	FALSE	0.998	2e-6	5.698970004336019	(AA)	0.211	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.998	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	14q31.2	14	83825919	Intergenic	RNU6ATAC28P - LINC02305	ENSG00000238561	ENSG00000258532	NA	75418	77518	rs140660435-C	rs140660435	0	140660435	intergenic_variant	TRUE	1.0	2e-6	5.698970004336019	(AA)	0.51	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	8p21.2	8	25274007	DOCK5	DOCK5	NA	NA	ENSG00000147459	NA	NA	rs190951784-A	rs190951784	0	190951784	intron_variant	FALSE	0.995	2e-6	5.698970004336019	(AA)	0.145	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.995	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	6q24.2	6	143952786	PLAGL1	PLAGL1	NA	NA	ENSG00000118495	NA	NA	rs150612539-C	rs150612539	0	150612539	intron_variant	FALSE	1.0	2e-6	5.698970004336019	(AA)	0.441	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	104730381	Intergenic	CXXC4-AS1	NA	NA	ENSG00000245384	NA	NA	rs73839334-A	rs73839334	0	73839334	intron_variant	FALSE	0.991	2e-6	5.698970004336019	(AA)	0.09	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.991	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q28	3	192299812	FGF12	FGF12	NA	NA	ENSG00000114279	NA	NA	rs149667740-G	rs149667740	0	149667740	intron_variant	FALSE	0.999	2e-6	5.698970004336019	(AA)	0.362	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	7p21.3	7	8412106	Intergenic	NA - NXPH1	NA	ENSG00000122584	NA	NA	21503	rs111751834-G	rs111751834	0	111751834	intergenic_variant	TRUE	0.954	2e-6	5.698970004336019	(AA)	0.039	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.954	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3p21.31	3	46869103	Intergenic	MYL3	NA	NA	ENSG00000160808	NA	NA	rs144261207-A	rs144261207	0	144261207	intron_variant	FALSE	0.997	2e-6	5.698970004336019	(AA)	0.179	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.997	NA	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	1p36.13	1	18649995	PAX7	PAX7	NA	NA	ENSG00000009709	NA	NA	rs9439714-?	rs9439714	0	9439714	intron_variant	FALSE	NR	8e-10	9.096910013008056	(EA)	1.47	[1.31-1.65]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.47	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	8q21.3	8	87856112	DCAF4L2	SOX5P1 - DCAF4L2	ENSG00000254376	ENSG00000176566	NA	66424	14635	rs12543318-?	rs12543318	0	12543318	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	(EA)	1.41	[1.26-1.58]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.41	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	8q24.21	8	128921474	intergenic	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs72728734-?	rs72728734	0	72728734	intron_variant	FALSE	NR	6e-26	25.221848749616356	(EA)	2.06	[1.81-2.35]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	2.06	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	17p13.1	17	9044391	NTN1	NTN1	NA	NA	ENSG00000065320	NA	NA	rs12944377-?	rs12944377	0	12944377	intron_variant	FALSE	NR	5e-10	9.301029995663981	(EA)	1.4925373	[1.32-1.67]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.4925373	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	17q23.2	17	62999067	TANC2	TRMT112P3 - TANC2	ENSG00000265262	ENSG00000170921	NA	47879	10489	rs1588366-?	rs1588366	0	1588366	regulatory_region_variant	TRUE	NR	9e-9	8.045757490560675	(EA)	1.5384616	[1.35-1.79]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.5384616	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	20p13	20	4002011	NR	RNF24	NA	NA	ENSG00000101236	NA	NA	rs113788813-?	rs113788813	0	113788813	intron_variant	FALSE	NR	6e-6	5.221848749616356	(EA)	3.08	[1.96-4.83]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	3.08	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	1p22.1	1	94092554	ARHGAP29	ABCA4	NA	NA	ENSG00000198691	NA	NA	rs66515264-?	rs66515264	0	66515264	intron_variant	FALSE	NR	2e-8	7.698970004336019	(Asian)	1.63	[1.39-1.91]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.63	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	1q32.2	1	209808680	IRF6	IRF6 - UTP25	ENSG00000117595	ENSG00000117597	NA	2505	19292	rs6540559-?	rs6540559	0	6540559	intergenic_variant	TRUE	NR	6e-16	15.221848749616356	(Asian)	1.6666665	[1.47-1.85]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.6666665	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	3q12.1	3	99982290	NR	CMSS1, FILIP1L	NA	NA	ENSG00000184220, ENSG00000168386	NA	NA	rs7616988-?	rs7616988	0	7616988	intron_variant	FALSE	NR	3e-6	5.522878745280337	(Asian)	1.5625	[1.32-1.85]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.5625	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	10q25.3	10	117086783	VAX1	SHTN1	NA	NA	ENSG00000187164	NA	NA	rs10886040-?	rs10886040	0	10886040	intron_variant	FALSE	NR	1e-7	7	(Asian)	1.39	[1.24-1.56]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.39	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	12q13.13	12	52963551	KRT18	KRT18 - EIF4B	ENSG00000111057	ENSG00000063046	NA	10645	42731	rs2363632-?	rs2363632	0	2363632	intergenic_variant	TRUE	NR	6e-6	5.221848749616356	(Asian)	1.3333333	[1.19-1.49]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.3333333	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	17p13.1	17	9039746	NTN1	NTN1	NA	NA	ENSG00000065320	NA	NA	rs9911652-?	rs9911652	0	9911652	intron_variant	FALSE	NR	3e-8	7.522878745280337	(Asian)	1.56	[1.35-1.81]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.56	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	20q12	20	40656135	MAFB	NA - MAFB	NA	ENSG00000204103	NA	NA	29713	rs6029258-?	rs6029258	0	6029258	intergenic_variant	TRUE	NR	4e-12	11.397940008672037	(Asian)	1.5384616	[1.37-1.72]	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.5384616	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	13q12.3	13	29572064	SLC7A1	SLC7A1	NA	NA	ENSG00000139514	NA	NA	rs63418562-C	rs63418562	1	9508495	intron_variant	FALSE	NA	4e-10	9.397940008672037	NA	0.253	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	13q12.3	13	29572064	SLC7A1	SLC7A1	NA	NA	ENSG00000139514	NA	NA	rs63418562-C	rs63418562	1	9508495	intron_variant	FALSE	NA	1e-7	7	(EA)	0.24	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1q42.3	1	236162705	GPR137B	GPR137B	NA	NA	ENSG00000077585	NA	NA	rs6428947-C	rs6428947	0	6428947	intron_variant	FALSE	NA	6e-6	5.221848749616356	NA	0.206	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1q43	1	243309499	SDCCAG8	SDCCAG8, SDCCAG8	NA	NA	ENSG00000054282, ENSG00000276111	NA	NA	rs6429422-T	rs6429422	0	6429422	intron_variant	FALSE	NA	5e-13	12.301029995663981	(EA)	0.3	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1q43	1	243309499	SDCCAG8	SDCCAG8, SDCCAG8	NA	NA	ENSG00000054282, ENSG00000276111	NA	NA	rs6429422-T	rs6429422	0	6429422	intron_variant	FALSE	NA	1e-12	12	NA	0.271	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	15q24.1	15	74833304	CPLX3, ULK3	CPLX3 - ULK3	ENSG00000213578	ENSG00000140474	NA	1502	2814	rs6495122-A	rs6495122	0	6495122	regulatory_region_variant	TRUE	NA	4e-6	5.3979400086720375	(EA)	0.188	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	15q24.1	15	74833304	CPLX3, ULK3	CPLX3 - ULK3	ENSG00000213578	ENSG00000140474	NA	1502	2814	rs6495122-A	rs6495122	0	6495122	regulatory_region_variant	TRUE	NA	5e-6	5.301029995663981	NA	0.171	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11p15.4	11	10004305	NR	SBF2	NA	NA	ENSG00000133812	NA	NA	rs66803065-C	rs66803065	0	66803065	intron_variant	FALSE	NA	1e-6	6	NA	0.221	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p14.1	3	64719689	ADAMTS9-AS2	ADAMTS9-AS2	NA	NA	ENSG00000241684	NA	NA	rs6795735-C	rs6795735	0	6795735	intron_variant	FALSE	NA	4e-6	5.3979400086720375	(EA)	0.177	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p21.31	3	48156124	MAP4, CDC25A	RN7SL664P - CDC25A	ENSG00000265078	ENSG00000164045	NA	61019	1022	rs6797587-A	rs6797587	0	6797587	regulatory_region_variant	TRUE	NA	5e-6	5.301029995663981	NA	0.17	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q24.12	12	111494996	NR	ATXN2	NA	NA	ENSG00000204842	NA	NA	rs7137828-C	rs7137828	0	7137828	intron_variant	FALSE	NA	4e-18	17.397940008672037	NA	0.32	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q24.12	12	111494996	NR	ATXN2	NA	NA	ENSG00000204842	NA	NA	rs7137828-C	rs7137828	0	7137828	intron_variant	FALSE	NA	7e-15	14.154901959985743	(EA)	0.304	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q24.12	12	111494996	NR	ATXN2	NA	NA	ENSG00000204842	NA	NA	rs7137828-C	rs7137828	0	7137828	intron_variant	FALSE	NA	4e-6	5.3979400086720375	(Latino)	0.613	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3q22.2	3	134167861	RYK	RYK	NA	NA	ENSG00000163785	NA	NA	rs75305034-T	rs75305034	1	55688777	intron_variant	FALSE	NA	6e-12	11.221848749616356	(EA)	0.286	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3q22.2	3	134167861	RYK	RYK	NA	NA	ENSG00000163785	NA	NA	rs75305034-T	rs75305034	1	55688777	intron_variant	FALSE	NA	1e-11	11	NA	0.266	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q31.2	2	178889467	CCDC141	CCDC141	NA	NA	ENSG00000163492	NA	NA	rs7591091-T	rs7591091	0	7591091	intron_variant	FALSE	NA	1e-8	8	NA	0.217	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q31.2	2	178889467	CCDC141	CCDC141	NA	NA	ENSG00000163492	NA	NA	rs7591091-T	rs7591091	0	7591091	intron_variant	FALSE	NA	1e-6	6	(EA)	0.202	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p11.1	3	88688891	C3orf38, EPHA3	NDUFA5P5 - NA	ENSG00000242365	NA	NA	87489	NA	rs76217164-T	rs76217164	0	76217164	intergenic_variant	TRUE	NA	1e-8	8	NA	2.038	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q32	5	149010732	NR	SH3TC2	NA	NA	ENSG00000169247	NA	NA	rs7704297-T	rs7704297	0	7704297	intron_variant	FALSE	NA	5e-8	7.301029995663981	NA	0.245	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q32	5	149010732	NR	SH3TC2	NA	NA	ENSG00000169247	NA	NA	rs7704297-T	rs7704297	0	7704297	intron_variant	FALSE	NA	3e-6	5.522878745280337	(EA)	0.229	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	8q24.12	8	119454719	NR	CCN3 - NA	ENSG00000136999	NA	NA	30285	NA	rs80309268-T	rs80309268	0	80309268	intron_variant	TRUE	NA	7e-9	8.154901959985743	(EA)	0.273	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	8q24.12	8	119454719	NR	CCN3 - NA	ENSG00000136999	NA	NA	30285	NA	rs80309268-T	rs80309268	0	80309268	intron_variant	TRUE	NA	3e-9	8.522878745280337	NA	0.265	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	19q12	19	31436641	TSHZ3, THEG5	TSHZ3-AS1 - LINC02841	ENSG00000267662	ENSG00000267407	NA	18847	83514	rs8105753-A	rs8105753	0	8105753	regulatory_region_variant	TRUE	NA	1e-6	6	(EA)	0.198	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	19q12	19	31436641	TSHZ3, THEG5	TSHZ3-AS1 - LINC02841	ENSG00000267662	ENSG00000267407	NA	18847	83514	rs8105753-A	rs8105753	0	8105753	regulatory_region_variant	TRUE	NA	3e-6	5.522878745280337	NA	0.173	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q12	4	53933078	LNX1-AS2, RPL21P44	LNX1 - RPL21P44	ENSG00000072201	ENSG00000229585	NA	231673	53509	rs871606-T	rs871606	0	871606	intron_variant	TRUE	NA	1e-8	8	NA	0.313	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p36.22	1	10736809	CASZ1	CASZ1	NA	NA	ENSG00000130940	NA	NA	rs880315-T	rs880315	0	880315	intron_variant	FALSE	NA	6e-8	7.221848749616356	NA	0.229	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p36.22	1	10736809	CASZ1	CASZ1	NA	NA	ENSG00000130940	NA	NA	rs880315-T	rs880315	0	880315	intron_variant	FALSE	NA	7e-6	5.154901959985743	(EA)	0.211	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q32	5	149011577	SH3TC2	SH3TC2	NA	NA	ENSG00000169247	NA	NA	rs9687065-A	rs9687065	0	9687065	intron_variant	FALSE	NA	1e-7	7	NA	0.239	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q32	5	149011577	SH3TC2	SH3TC2	NA	NA	ENSG00000169247	NA	NA	rs9687065-A	rs9687065	0	9687065	intron_variant	FALSE	NA	4e-6	5.3979400086720375	(EA)	0.226	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p22.1	3	41871159	ULK4	ULK4	NA	NA	ENSG00000168038	NA	NA	rs9815354-G	rs9815354	0	9815354	intron_variant	FALSE	NA	3e-13	12.522878745280337	NA	0.346	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p22.1	3	41871159	ULK4	ULK4	NA	NA	ENSG00000168038	NA	NA	rs9815354-G	rs9815354	0	9815354	intron_variant	FALSE	NA	3e-11	10.522878745280337	(EA)	0.345	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p22.1	3	41871159	ULK4	ULK4	NA	NA	ENSG00000168038	NA	NA	rs9815354-G	rs9815354	0	9815354	intron_variant	FALSE	NA	1e-19	19	NA	0.437	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10q24.32	10	102834750	CYP17A1	CYP17A1	NA	NA	ENSG00000148795	NA	NA	rs1004467-A	rs1004467	0	1004467	non_coding_transcript_exon_variant	FALSE	NA	1e-13	13	(EA)	0.499	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10q24.32	10	102834750	CYP17A1	CYP17A1	NA	NA	ENSG00000148795	NA	NA	rs1004467-A	rs1004467	0	1004467	non_coding_transcript_exon_variant	FALSE	NA	3e-19	18.522878745280337	NA	0.498	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2p16.1	2	55812964	PNPT1, EFEMP1	NA - EFEMP1	NA	ENSG00000115380	NA	NA	53003	rs10199082-T	rs10199082	0	10199082	intergenic_variant	TRUE	NA	7e-6	5.154901959985743	(EA)	0.264	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7p12.3	7	45970501	IGFBP3, TNS3	IGFBP3 - FTLP15	ENSG00000146674	ENSG00000233952	NA	48627	27039	rs10260816-C	rs10260816	0	10260816	intron_variant	TRUE	NA	9e-16	15.045757490560675	(EA)	0.328	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7p12.3	7	45970501	IGFBP3, TNS3	IGFBP3 - FTLP15	ENSG00000146674	ENSG00000233952	NA	48627	27039	rs10260816-C	rs10260816	0	10260816	intron_variant	TRUE	NA	2e-20	19.69897000433602	NA	0.344	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	15q21.1	15	48622729	FBN1	FBN1	NA	NA	ENSG00000166147	NA	NA	rs1036477-A	rs1036477	0	1036477	intron_variant	FALSE	NA	1e-9	9	NA	0.325	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	15q21.1	15	48622729	FBN1	FBN1	NA	NA	ENSG00000166147	NA	NA	rs1036477-A	rs1036477	0	1036477	intron_variant	FALSE	NA	2e-11	10.698970004336019	(EA)	0.431	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	19p13.12	19	15167997	NOTCH3	NOTCH3	NA	NA	ENSG00000074181	NA	NA	rs10418305-C	rs10418305	0	10418305	intron_variant	FALSE	NA	9e-7	6.045757490560675	(EA)	0.321	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	19p13.12	19	15167997	NOTCH3	NOTCH3	NA	NA	ENSG00000074181	NA	NA	rs10418305-C	rs10418305	0	10418305	intron_variant	FALSE	NA	6e-11	10.221848749616356	NA	0.368	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	9q33.2	9	122993292	RABGAP1	RABGAP1	NA	NA	ENSG00000011454	NA	NA	rs10818775-C	rs10818775	0	10818775	intron_variant	FALSE	NA	3e-6	5.522878745280337	(EA)	0.293	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	9q33.2	9	122993292	RABGAP1	RABGAP1	NA	NA	ENSG00000011454	NA	NA	rs10818775-C	rs10818775	0	10818775	intron_variant	FALSE	NA	1e-7	7	NA	0.27	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11p11.2	11	45211922	PRDM11	PRDM11	NA	NA	ENSG00000019485	NA	NA	rs10838433-G	rs10838433	0	10838433	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	0.19	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q24.3	11	130396222	NR	ZBTB44-DT	NA	NA	ENSG00000175773	NA	NA	rs10894192-T	rs10894192	0	10894192	intron_variant	FALSE	NA	2e-18	17.69897000433602	(EA)	0.365	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q24.3	11	130396222	NR	ZBTB44-DT	NA	NA	ENSG00000175773	NA	NA	rs10894192-T	rs10894192	0	10894192	intron_variant	FALSE	NA	7e-6	5.154901959985743	(Latino)	0.598	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q24.3	11	130396222	NR	ZBTB44-DT	NA	NA	ENSG00000175773	NA	NA	rs10894192-T	rs10894192	0	10894192	intron_variant	FALSE	NA	1e-21	21	NA	0.369	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10p11.22	10	31123632	ZNF438, ZEB1-AS1	ZNF438 - LINC02664	ENSG00000183621	ENSG00000272381	NA	91695	64083	rs11008355-G	rs11008355	0	11008355	intron_variant	TRUE	NA	1e-7	7	NA	0.219	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10p11.22	10	31123632	ZNF438, ZEB1-AS1	ZNF438 - LINC02664	ENSG00000183621	ENSG00000272381	NA	91695	64083	rs11008355-G	rs11008355	0	11008355	intron_variant	TRUE	NA	5e-7	6.301029995663981	(EA)	0.235	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q21.33	12	89632685	NR	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs11105352-G	rs11105352	0	11105352	intron_variant	FALSE	NA	7e-9	8.154901959985743	(EA)	0.316	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	6q23.3	6	135097778	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs7776054-A	rs7776054	0	7776054	intron_variant	FALSE	0.72	4e-8	7.3979400086720375	(Asian initial, BMI unadjusted)	0.051	[0.033-0.069] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.72	NA	0.051
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	1q21.3	1	150986360	ANXA9, CERS2	ANXA9	NA	NA	ENSG00000143412	NA	NA	rs267733-A	rs267733	0	267733	missense_variant	FALSE	0.863	4e-8	7.3979400086720375	(Trans-ethnic initial)	0.0331	[0.023-0.043] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.863	NA	0.0331
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	3p22.3	3	32496755	CMTM6	CMTM6	NA	NA	ENSG00000091317	NA	NA	rs3773777-T	rs3773777	0	3773777	intron_variant	FALSE	0.0937	7e-8	7.154901959985743	(Trans-ethnic initial)	0.0402	[0.026-0.054] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.0937	NA	0.0402
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	17p13.1	17	8257831	PFAS	PFAS	NA	NA	ENSG00000178921	NA	NA	rs4791641-T	rs4791641	0	4791641	missense_variant	FALSE	0.543	1e-7	7	(Trans-ethnic initial)	0.0202	[0.013-0.027] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.543	NA	0.0202
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	16q22.2	16	72074194	HPR	HPR, TXNL4B	NA	NA	ENSG00000261701, ENSG00000140830	NA	NA	rs2000999-A	rs2000999	0	2000999	intron_variant	FALSE	0.266	2e-6	5.698970004336019	(Asian initial, BMI unadjusted)	0.0518	[0.031-0.073] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.266	NA	0.0518
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	20q12	20	41095698	MAFB	TOP1	NA	NA	ENSG00000198900	NA	NA	rs6065311-T	rs6065311	0	6065311	non_coding_transcript_exon_variant	FALSE	0.194	3e-6	5.522878745280337	(Asian initial, BMI unadjusted)	0.0485	[0.028-0.069] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.194	NA	0.0485
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	20q12	20	41095698	TOP1	TOP1	NA	NA	ENSG00000198900	NA	NA	rs6065311-T	rs6065311	0	6065311	non_coding_transcript_exon_variant	FALSE	0.194	3e-6	5.522878745280337	(Asian initial, BMI unadjusted)	0.0485	[0.028-0.069] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.194	NA	0.0485
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q21.2	17	41849398	RP11-156E6.1	KLHL11	NA	NA	ENSG00000178502	NA	NA	rs11079018-G	rs11079018	0	11079018	3_prime_UTR_variant	FALSE	0.9176	3e-19	18.522878745280337	NA	0.05845597	[0.046-0.071] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.9176	NA	0.05845597
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q21.31	17	44201473	CTB-175E5.7	ATXN7L3-AS1	NA	NA	ENSG00000267394	NA	NA	rs9303601-G	rs9303601	0	9303601	intron_variant	FALSE	0.8623	3e-10	9.522878745280337	NA	0.03281738	[0.023-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.8623	NA	0.03281738
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q21.31	17	46115252	KANSL1	KANSL1, KANSL1, KANSL1	NA	NA	ENSG00000120071, ENSG00000275867, ENSG00000278458	NA	NA	rs4606752-G	rs4606752	0	4606752	intron_variant	FALSE	0.2267	2e-16	15.698970004336019	NA	0.03470527	[0.026-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2267	NA	0.03470527
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q25.1	17	76387027	SPHK1	SPHK1	NA	NA	ENSG00000176170	NA	NA	rs549579958-C	rs549579958	0	549579958	frameshift_variant	FALSE	0.004	2e-29	28.69897000433602	NA	0.3300637	[0.27-0.39] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.004	NA	0.3300637
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q25.1	17	76464800	AANAT	AANAT	NA	NA	ENSG00000129673	NA	NA	rs386386678-ATT	rs386386678	1	56837304	intron_variant	FALSE	0.6703	3e-21	20.522878745280337	NA	0.03687562	[0.029-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.6703	NA	0.03687562
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q25.3	17	77376768	RP11-936I5.1	SEPTIN9	NA	NA	ENSG00000184640	NA	NA	rs4789452-A	rs4789452	0	4789452	non_coding_transcript_exon_variant	FALSE	0.483	5e-15	14.301029995663981	NA	0.02808327	[0.021-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.483	NA	0.02808327
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q25.3	17	78123212	TMC6	TMC6	NA	NA	ENSG00000141524	NA	NA	rs3794738-T	rs3794738	0	3794738	intron_variant	FALSE	0.0796	1e-11	11	NA	0.04477281	[0.032-0.058] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0796	NA	0.04477281
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q25.3	17	78128765	TMC6	TMC6	NA	NA	ENSG00000141524	NA	NA	rs2748425-C	rs2748425	0	2748425	5_prime_UTR_variant	FALSE	0.1905	6e-17	16.221848749616356	NA	0.03860149	[0.03-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1905	NA	0.03860149
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q25.3	17	78138386	TMC8	TMC8	NA	NA	ENSG00000167895	NA	NA	rs144120533-T	rs144120533	0	144120533	missense_variant	FALSE	0.0031	4e-10	9.397940008672037	NA	0.2145151	[0.15-0.28] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0031	NA	0.2145151
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q25.3	17	78248202	THA1P	TMEM235 - THA1P	ENSG00000204278	ENSG00000267676	NA	7215	291	rs72901753-C	rs72901753	0	72901753	non_coding_transcript_exon_variant	TRUE	0.3268	2e-16	15.698970004336019	NA	0.03155672	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3268	NA	0.03155672
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q25.3	17	80138078	EIF4A3	EIF4A3	NA	NA	ENSG00000141543	NA	NA	rs2361710-C	rs2361710	0	2361710	intron_variant	FALSE	0.4724	3e-21	20.522878745280337	NA	0.03386273	[0.027-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4724	NA	0.03386273
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	18q11.2	18	23469770	RIOK3	RIOK3	NA	NA	ENSG00000101782	NA	NA	rs140271614-A	rs140271614	0	140271614	intron_variant	FALSE	0.0065	1e-12	12	NA	0.1745625	[0.13-0.22] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0065	NA	0.1745625
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	18q11.2	18	23768176	LAMA3	LAMA3	NA	NA	ENSG00000053747	NA	NA	rs556443619-C	rs556443619	0	556443619	intron_variant	FALSE	0.0058	6e-9	8.221848749616356	NA	0.146628	[0.097-0.196] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0058	NA	0.146628
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	18q21.1	18	46236831	C18orf25	C18orf25	NA	NA	ENSG00000152242	NA	NA	rs11356507-G	rs11356507	0	11356507	intron_variant	FALSE	0.6373	7e-10	9.154901959985743	NA	0.02389735	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.6373	NA	0.02389735
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	18q21.33	18	63178651	BCL2	BCL2	NA	NA	ENSG00000171791	NA	NA	rs12454712-C	rs12454712	0	12454712	intron_variant	FALSE	0.3778	5e-10	9.301029995663981	NA	0.02299066	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3778	NA	0.02299066
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	19p13.3	19	898288	R3HDM4	R3HDM4	NA	NA	ENSG00000198858	NA	NA	rs12985393-T	rs12985393	0	12985393	intron_variant	FALSE	0.2965	3e-10	9.522878745280337	NA	0.02550716	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2965	NA	0.02550716
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	19p13.3	19	906510	R3HDM4	R3HDM4	NA	NA	ENSG00000198858	NA	NA	rs111932385-A	rs111932385	0	111932385	intron_variant	FALSE	0.0166	3e-22	21.522878745280337	NA	0.1465017	[0.12-0.18] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0166	NA	0.1465017
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	19p13.3	19	913048	R3HDM4	R3HDM4	NA	NA	ENSG00000198858	NA	NA	rs1683587-C	rs1683587	0	1683587	intron_variant	FALSE	0.5151	7e-43	42.15490195998574	NA	0.05288179	[0.045-0.06] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.5151	NA	0.05288179
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	19p13.3	19	1164199	SBNO2	SBNO2	NA	NA	ENSG00000064932	NA	NA	rs35971149-C	rs35971149	0	35971149	intron_variant	FALSE	0.3099	5e-21	20.30102999566398	NA	0.03683046	[0.029-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3099	NA	0.03683046
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	19p13.3	19	4502189	HDGFRP2	HDGFL2, PLIN4	NA	NA	ENSG00000167674, ENSG00000167676	NA	NA	rs8887-C	rs8887	0	8887	3_prime_UTR_variant	FALSE	0.5713	8e-17	16.096910013008056	NA	0.03064393	[0.023-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.5713	NA	0.03064393
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	19p13.2	19	10224049	S1PR2	DNMT1, S1PR2	NA	NA	ENSG00000130816, ENSG00000267534	NA	NA	rs117064827-G	rs117064827	0	117064827	missense_variant	FALSE	0.0085	4e-9	8.397940008672037	NA	0.1210407	[0.081-0.161] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0085	NA	0.1210407
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	19p13.2	19	10239973	intergenic	S1PR2 - MRPL4	ENSG00000267534	ENSG00000105364	NA	8642	11928	rs8113613-T	rs8113613	0	8113613	regulatory_region_variant	TRUE	0.1876	5e-30	29.30102999566398	NA	0.05245495	[0.043-0.061] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1876	NA	0.05245495
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	SLC44A2	NA	NA	NA	NA	NA	NA	chr19:10739143-C	chr19:10739143	0	NA	NA	TRUE	0.7766	6e-45	44.221848749616356	NA	0.06059459	[0.052-0.069] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.7766	NA	0.06059459
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	19p13.2	19	11181407	KANK2	KANK2	NA	NA	ENSG00000197256	NA	NA	rs74180173-T	rs74180173	0	74180173	intron_variant	FALSE	0.084	3e-160	159.52287874528034	NA	0.1745118	[0.16-0.19] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.084	NA	0.1745118
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	19p13.13	19	12870439	HOOK2, MAST1	HOOK2, MAST1	NA	NA	ENSG00000095066, ENSG00000105613	NA	NA	rs11672387-G	rs11672387	0	11672387	intron_variant	FALSE	0.2174	4e-16	15.397940008672037	NA	0.03552593	[0.027-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2174	NA	0.03552593
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	14q11.2	14	23030112	PSMB5	PSMB5	NA	NA	ENSG00000100804	NA	NA	rs113525195-A	rs113525195	0	113525195	intron_variant	FALSE	0.2767	1e-23	23	NA	0.04020318	[0.032-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2767	NA	0.04020318
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	14q13.1	14	34772048	BAZ1A	BAZ1A	NA	NA	ENSG00000198604	NA	NA	rs113131010-A	rs113131010	0	113131010	intron_variant	FALSE	0.1006	2e-18	17.69897000433602	NA	0.05259724	[0.041-0.064] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1006	NA	0.05259724
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	SPTB	NA	NA	NA	NA	NA	NA	chr14:65281472-C	chr14:65281472	0	NA	NA	TRUE	0.3104	9e-12	11.045757490560675	NA	0.02653764	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3104	NA	0.02653764
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	14q24.1	14	67416907	PLEK2	PLEK2 - MIR5694	ENSG00000100558	ENSG00000265993	NA	4740	24948	rs17248895-C	rs17248895	0	17248895	regulatory_region_variant	TRUE	0.1031	4e-12	11.397940008672037	NA	0.040864	[0.029-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1031	NA	0.040864
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	14q24.3	14	73741643	ELMSAN1	MIDEAS	NA	NA	ENSG00000156030	NA	NA	rs533217053-C	rs533217053	0	533217053	intron_variant	FALSE	0.0071	4e-22	21.397940008672037	NA	0.2102778	[0.17-0.25] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0071	NA	0.2102778
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	NA	NA	NA	RN7SL546P	NA	NA	NA	NA	NA	NA	chr14:103044709-GA	chr14:103044709	0	NA	NA	TRUE	0.2944	6e-10	9.221848749616356	NA	0.02453828	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2944	NA	0.02453828
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	14q32.33	14	103525141	RP11-600F24.7	CKB - TRMT61A	ENSG00000166165	ENSG00000166166	NA	2308	4055	rs2765041-A	rs2765041	0	2765041	non_coding_transcript_exon_variant	TRUE	0.7101	3e-10	9.522878745280337	NA	0.02492265	[0.017-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.7101	NA	0.02492265
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	15q22.2	15	62508256	TLN2	TLN2	NA	NA	ENSG00000171914	NA	NA	rs812957-G	rs812957	0	812957	intron_variant	FALSE	0.2737	2e-21	20.69897000433602	NA	0.03818624	[0.03-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2737	NA	0.03818624
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	15q22.2	15	62800701	TLN2	TLN2	NA	NA	ENSG00000171914	NA	NA	rs35997243-C	rs35997243	0	35997243	missense_variant	FALSE	0.0146	4e-15	14.397940008672037	NA	0.1173148	[0.088-0.147] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0146	NA	0.1173148
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	15q22.31	15	63506371	USP3	USP3	NA	NA	ENSG00000140455	NA	NA	rs35639661-G	rs35639661	0	35639661	intron_variant	FALSE	0.6465	2e-13	12.698970004336019	NA	0.0278086	[0.02-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.6465	NA	0.0278086
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	15q25.1	15	80054439	intergenic	BCL2A1 - Metazoa_SRP	ENSG00000140379	ENSG00000278007	NA	83243	2986	rs34483751-A	rs34483751	0	34483751	regulatory_region_variant	TRUE	0.6368	8e-12	11.096910013008056	NA	0.02586678	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.6368	NA	0.02586678
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	16p13.3	16	165107	HBZP1	HBZP1, HBM	NA	NA	ENSG00000206178, ENSG00000206177	NA	NA	rs7194649-A	rs7194649	0	7194649	non_coding_transcript_exon_variant	FALSE	0.1058	8e-25	24.096910013008056	NA	0.06153466	[0.05-0.073] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1058	NA	0.06153466
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	16p13.3	16	168533	HBA2, Z84721.4	HBM - HBAP1	ENSG00000206177	ENSG00000225323	NA	1769	146	rs1203833-C	rs1203833	0	1203833	intergenic_variant	TRUE	0.1788	2e-18	17.69897000433602	NA	0.04127893	[0.032-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1788	NA	0.04127893
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	16q22.1	16	68796765	CDH1	CDH1	NA	NA	ENSG00000039068	NA	NA	rs71382075-GA	rs71382075	1	35199353	intron_variant	FALSE	0.3078	4e-15	14.397940008672037	NA	0.03067081	[0.023-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.3078	NA	0.03067081
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	16q24.1	16	84747007	USP10	USP10	NA	NA	ENSG00000103194	NA	NA	rs12920732-T	rs12920732	0	12920732	intron_variant	FALSE	0.2204	1e-9	9	NA	0.02620205	[0.018-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2204	NA	0.02620205
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	16q24.3	16	88718246	PIEZO1	PIEZO1	NA	NA	ENSG00000103335	NA	NA	rs562212325-C	rs562212325	0	562212325	non_coding_transcript_exon_variant	FALSE	0.0015	5e-16	15.301029995663981	NA	0.3739617	[0.28-0.46] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0015	NA	0.3739617
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	16q24.3	16	88732112	PIEZO1, RP5-1142A6.2	PIEZO1	NA	NA	ENSG00000103335	NA	NA	rs567292015-A	rs567292015	0	567292015	intron_variant	FALSE	0.0066	1e-9	9	NA	0.1531636	[0.1-0.2] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0066	NA	0.1531636
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	16q24.3	16	88792238	intergenic	PIEZO1 - CDT1	ENSG00000103335	ENSG00000167513	NA	7018	11551	rs2968478-G	rs2968478	0	2968478	intergenic_variant	TRUE	0.5806	2e-14	13.698970004336019	NA	0.02842473	[0.021-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.5806	NA	0.02842473
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	16q24.3	16	89873521	TCF25	SPIRE2 - TCF25	ENSG00000204991	ENSG00000141002	NA	2202	49	rs9939914-C	rs9939914	0	9939914	regulatory_region_variant	TRUE	0.2539	4e-13	12.397940008672037	NA	0.03026111	[0.022-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.2539	NA	0.03026111
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17p11.2	17	20034096	SPECC1	SPECC1	NA	NA	ENSG00000128487	NA	NA	rs34012755-C	rs34012755	0	34012755	intron_variant	FALSE	0.4076	2e-15	14.698970004336019	NA	0.0292643	[0.022-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4076	NA	0.0292643
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q11.2	17	28856086	ERAL1	ERAL1	NA	NA	ENSG00000132591	NA	NA	rs9914988-A	rs9914988	0	9914988	intron_variant	FALSE	0.7961	2e-29	28.69897000433602	NA	0.049934	[0.041-0.059] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.7961	NA	0.049934
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q11.2	17	32857613	MYO1D	MYO1D	NA	NA	ENSG00000176658	NA	NA	rs17183628-C	rs17183628	0	17183628	intron_variant	FALSE	0.1883	5e-14	13.301029995663981	NA	0.03456426	[0.026-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.1883	NA	0.03456426
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q12	17	35553481	RP11-1094M14.12	SLFN14	NA	NA	ENSG00000236320	NA	NA	rs36064799-CA	rs36064799	0	36064799	non_coding_transcript_exon_variant	FALSE	0.0463	1e-14	14	NA	0.06594627	[0.049-0.083] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.0463	NA	0.06594627
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q12	17	35619088	AP2B1	AP2B1	NA	NA	ENSG00000006125	NA	NA	rs225245-G	rs225245	0	225245	intron_variant	FALSE	0.4562	2e-39	38.69897000433602	NA	0.04732168	[0.04-0.054] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.4562	NA	0.04732168
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals	NA	17q12	17	35649600	AP2B1	AP2B1	NA	NA	ENSG00000006125	NA	NA	rs9915021-T	rs9915021	0	9915021	intron_variant	FALSE	0.064	2e-28	27.69897000433602	NA	0.08090267	[0.067-0.095] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004611	Genome-wide genotyping array	0.064	NA	0.08090267
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	3p14.3	3	55978784	ERC2, MIR3938, RNA5SP133	ERC2	NA	NA	ENSG00000187672	NA	NA	rs1458065-A	rs1458065	0	1458065	intron_variant	FALSE	NR	2e-6	5.698970004336019	(daytime napping duration)	0.1346	[0.079-0.191] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	3q22.2	3	135255687	EPHB1	EPHB1	NA	NA	ENSG00000154928	NA	NA	rs181744922-A	rs181744922	0	181744922	intron_variant	FALSE	NR	3e-6	5.522878745280337	(daytime napping duration)	0.1091	[0.063-0.155] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	3q24	3	147667836	ZIC1	NPM1P28 - NA	ENSG00000240804	NA	NA	76001	NA	rs2319326-T	rs2319326	0	2319326	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(daytime napping duration)	0.1073	[0.063-0.152] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	5p13.2	5	34703825	RAI14, TTC23L, RPL21P54, RAD1	RAI14	NA	NA	ENSG00000039560	NA	NA	rs115788537-A	rs115788537	0	115788537	intron_variant	FALSE	NR	9e-6	5.045757490560675	(daytime napping duration)	0.1662	[0.093-0.24] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	6p12.3	6	48504255	NA	NA	NA	NA	NA	NA	NA	rs144310471-C	rs144310471	0	144310471	intergenic_variant	TRUE	NR	9e-6	5.045757490560675	(daytime napping duration)	0.2414	[0.13-0.35] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	7p21.3	7	7273104	AC005532.5, C1GALT1, COL28A1, MIR3683	C1GALT1 - COL28A1	ENSG00000106392	ENSG00000215018	NA	24488	83099	rs7782993-G	rs7782993	0	7782993	intron_variant	TRUE	NR	2e-6	5.698970004336019	(daytime napping duration)	0.08231	[0.049-0.116] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	8p21.3	8	20639672	NA	NA - CCDC26	NA	ENSG00000229140	NA	NA	107994527	rs13270892-G	rs13270892	0	13270892	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(daytime napping duration)	0.1206	[0.07-0.171] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	NA	NA	NA	PHYHIPL, FAM13C	NA	NA	NA	NA	NA	NA	chr10:60940009-CAT	chr10:60940009	0	NA	NA	TRUE	NR	4e-6	5.3979400086720375	(daytime napping duration)	0.2344	[0.14-0.33] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	1p36.12	1	22068758	CDC42, CDC42-IT1, LINC00339, WNT4	CDC42, MPHOSPH6P1	NA	NA	ENSG00000070831, ENSG00000271428	NA	NA	rs2473317-G	rs2473317	0	2473317	non_coding_transcript_exon_variant	FALSE	NR	3e-6	5.522878745280337	(daytime napping)	0.8577	[0.5-1.22] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	3p25.3	3	9594976	DUSP5P2, LHFPL4, MTMR14, CPNE9	LHFPL4 - DUSP5P2	ENSG00000156959	ENSG00000235338	NA	41154	5772	rs6443245-T	rs6443245	0	6443245	intergenic_variant	TRUE	NR	1e-6	6	(daytime napping)	0.6256	[0.37-0.88] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	4q31.21	4	144500689	KRT18P51, HHIP-AS1, HHIP	NA - KRT18P51	NA	ENSG00000250504	NA	NA	71549	rs13133820-T	rs13133820	0	13133820	intron_variant	TRUE	NR	2e-6	5.698970004336019	(daytime napping)	0.5775	[0.34-0.82] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	5q14.3	5	86093562	PTP4A1P4, NBPF22P	PTP4A1P4 - NA	ENSG00000250359	NA	NA	5715	NA	rs2161208-T	rs2161208	0	2161208	intergenic_variant	TRUE	NR	1e-7	7	(daytime napping)	0.7025	[0.44-0.96] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	5q33.3	5	157237968	ITK, AC010609.1, CYFIP2, FAM71B	ITK	NA	NA	ENSG00000113263	NA	NA	rs30117-T	rs30117	0	30117	intron_variant	FALSE	NR	7e-6	5.154901959985743	(daytime napping)	0.6067	[0.34-0.87] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	5q35.3	5	179629159	HNRNPH1, C5orf60, RUFY1, CBY3, CANX, HMGB3P22	Metazoa_SRP, HNRNPH1, HNRNPH1	NA	NA	ENSG00000278007, ENSG00000284254, ENSG00000169045	NA	NA	rs113817606-C	rs113817606	0	113817606	non_coding_transcript_exon_variant	FALSE	NR	7e-7	6.154901959985743	(daytime napping)	1.117	[0.68-1.56] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	6p25.3	6	1539849	FOXC1, GMDS, FOXF2, FOXQ1	RN7SL352P - FOXCUT	ENSG00000243439	ENSG00000280916	NA	32251	61805	rs62388641-T	rs62388641	0	62388641	intergenic_variant	TRUE	NR	1e-6	6	(daytime napping)	0.8067	[0.48-1.13] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	10q11.22	10	48461099	ARHGAP22, MAPK8, ARHGAP22-IT1, FRMPD2	ARHGAP22	NA	NA	ENSG00000128805	NA	NA	rs4838594-C	rs4838594	0	4838594	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(daytime napping)	0.6979	[0.4-1] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	20q13.11	20	43465834	SRSF6, L3MBTL1, EIF4EBP2P, SGK2	SRSF6	NA	NA	ENSG00000124193	NA	NA	rs2064279-T	rs2064279	0	2064279	intron_variant	FALSE	NR	5e-6	5.301029995663981	(daytime napping duration)	0.0767	[0.044-0.109] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	14q21.2	14	43060562	NA	NA	NA	NA	NA	NA	NA	rs117097805-A	rs117097805	0	117097805	intergenic_variant	TRUE	NR	7e-8	7.154901959985743	(daytime napping)	1.783	[1.13-2.43] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	3p24.3	3	22592270	HMGB1P5, ZNF385D	NA	NA	NA	NA	NA	NA	rs6550704-A	rs6550704	0	6550704	intergenic_variant	TRUE	NR	5e-8	7.301029995663981	(daytime napping duration, weekdays)	0.0943	[0.06-0.128] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	2q23.2	2	149436805	LYPD6, AC007394.3, FAM8A3P, MMADHC	LYPD6	NA	NA	ENSG00000187123	NA	NA	rs951188-A	rs951188	0	951188	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(daytime napping, weekdays)	0.7008	[0.4-1] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	3q24	3	147698613	ZIC1	NA	NA	NA	NA	NA	NA	rs73151930-C	rs73151930	0	73151930	regulatory_region_variant	TRUE	NR	1e-6	6	(daytime napping duration, weekdays)	0.1041	[0.062-0.146] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	4q13.1	4	60737438	MIR548AG1	NA - LINC02496	NA	ENSG00000249066	NA	NA	13137	rs13132569-C	rs13132569	0	13132569	intergenic_variant	TRUE	NR	7e-7	6.154901959985743	(daytime napping, weekdays)	0.6402	[0.39-0.89] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	6q14.1	6	79878444	RP1-92C4.2, ELOVL4, GAPDHP63, RPL35AP18	LINC01621 - ELOVL4	ENSG00000235357	ENSG00000118402	NA	45058	36370	rs6919854-T	rs6919854	0	6919854	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	(daytime napping duration, weekdays)	0.07633	[0.043-0.11] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	5q35.3	5	179629110	HNRNPH1, C5orf60, RUFY1, CBY3, CANX, HMGB3P22	HNRNPH1, HNRNPH1	NA	NA	ENSG00000284254, ENSG00000169045	NA	NA	rs61078164-G	rs61078164	0	61078164	intron_variant	FALSE	NR	1e-6	6	(daytime napping, weekdays)	0.7744	[0.46-1.08] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	6q21	6	106692991	RP1-60O19.2, QRSL1, RPL21P65, RTN4IP1	QRSL1 - LINC02526	ENSG00000130348	ENSG00000229654	NA	24574	2544	rs3121446-A	rs3121446	0	3121446	regulatory_region_variant	TRUE	NR	8e-6	5.096910013008056	(daytime napping duration, weekdays)	0.08029	[0.045-0.115] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	NA	NA	NA	TEX15, PURG, PPP2CB, WRN	NA	NA	NA	NA	NA	NA	chr8:30765196-T	chr8:30765196	0	NA	NA	TRUE	NR	2e-6	5.698970004336019	(daytime napping duration, weekdays)	0.1055	[0.062-0.149] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	NA	NA	NA	SNX29, CPPED1, MIR4718	NA	NA	NA	NA	NA	NA	chr16:12662159-G	chr16:12662159	0	NA	NA	TRUE	NR	2e-6	5.698970004336019	(daytime napping, weekdays)	0.6289	[0.37-0.89] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	12p12.3	12	18899829	CAPZA3, PLCZ1, PSMC1P9, PLEKHA5	NA	NA	NA	NA	NA	NA	rs117595305-T	rs117595305	0	117595305	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(daytime napping duration, weekdays)	0.2291	[0.13-0.32] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	20p12.3	20	8897634	PLCB1, RNU105B, PLCB4	PLCB1	NA	NA	ENSG00000182621	NA	NA	rs67702392-C	rs67702392	0	67702392	intron_variant	FALSE	NR	6e-7	6.221848749616356	(daytime napping, weekdays)	0.685	[0.42-0.95] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	21q21.3	21	27517813	NCSTNP1, RPL10P1, EIF4A1P1, LINC00113	NCSTNP1 - NA	ENSG00000219592	NA	NA	25552	NA	rs242364-C	rs242364	0	242364	intergenic_variant	TRUE	NR	9e-6	5.045757490560675	(daytime napping duration, weekdays)	0.09077	[0.051-0.131] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	12q12	12	40301293	LRRK2, MUC19, SLC2A13, RPL30P13	LRRK2	NA	NA	ENSG00000188906	NA	NA	rs10878340-A	rs10878340	0	10878340	intron_variant	FALSE	NR	8e-7	6.096910013008056	(daytime napping duration)	0.07931	[0.048-0.111] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	12q15	12	67837461	IFNG-AS1, RPL39P28, DYRK2	NA - LINC01479	NA	ENSG00000255772	NA	NA	91774	rs10878674-G	rs10878674	0	10878674	intergenic_variant	TRUE	NR	9e-6	5.045757490560675	(daytime napping duration)	0.07141	[0.04-0.103] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	15q26.1	15	90737980	BLM, CRTC3, FURIN, FES	BLM	NA	NA	ENSG00000197299	NA	NA	rs35787687-C	rs35787687	0	35787687	intron_variant	FALSE	NR	9e-6	5.045757490560675	(daytime napping duration)	0.09091	[0.051-0.131] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	20p12.1	20	13072023	SPTLC3, ISM1, ISM1-AS1, TASP1	SPTLC3	NA	NA	ENSG00000172296	NA	NA	rs2073302-A	rs2073302	0	2073302	intron_variant	FALSE	NR	3e-7	6.522878745280337	(daytime napping duration)	0.08531	[0.053-0.118] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	12q24.13	12	113756471	RP11-438N16.1, RBM19	LINC01234	NA	NA	ENSG00000249550	NA	NA	rs35785195-G	rs35785195	0	35785195	intron_variant	FALSE	NR	2e-6	5.698970004336019	(daytime napping)	0.6981	[0.41-0.99] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	1q44	1	245329663	KIF26B, EFCAB2	KIF26B	NA	NA	ENSG00000162849	NA	NA	rs34938134-T	rs34938134	0	34938134	intron_variant	FALSE	NR	8e-6	5.096910013008056	(daytime napping duration, weekdays)	0.1187	[0.067-0.171] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	20p12.1	20	13065943	SPTLC3, ISM1, ISM1-AS1, TASP1	SPTLC3	NA	NA	ENSG00000172296	NA	NA	rs6109680-G	rs6109680	0	6109680	intron_variant	FALSE	NR	3e-6	5.522878745280337	(daytime napping)	0.6066	[0.35-0.86] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	3p22.2	3	39243701	CX3CR1, XIRP1, CCR8, CSRNP1	DSTNP4 - CX3CR1	ENSG00000215034	ENSG00000168329	NA	29029	19794	rs4276125-A	rs4276125	0	4276125	regulatory_region_variant	TRUE	NR	8e-6	5.096910013008056	(daytime napping duration, weekdays)	0.1155	[0.065-0.166] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	2q32.2	2	190578143	TMEM194B, NAB1, MFSD6, INPP1	RN7SKP179 - NAB1	ENSG00000251935	ENSG00000138386	NA	24663	68603	rs62182887-A	rs62182887	0	62182887	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(daytime napping, weekdays)	1.15	[0.67-1.63] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	6q13	6	70998270	B3GAT2, SMAP1, LYPLA1P3	B3GAT2 - BECN1P2	ENSG00000112309	ENSG00000219669	NA	41210	77294	rs9354951-A	rs9354951	0	9354951	regulatory_region_variant	TRUE	NR	4e-6	5.3979400086720375	(daytime napping duration, weekdays)	0.07869	[0.045-0.112] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	NA	NA	NA	RICTOR, OSMR, AIG1P1, FYB	NA	NA	NA	NA	NA	NA	chr5:38954206-C	chr5:38954206	0	NA	NA	TRUE	NR	3e-6	5.522878745280337	(daytime napping, weekdays)	0.5178	[0.3-0.74] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	6q14.1	6	79881546	ELOVL4, GAPDHP63, RPL35AP18, TTK	LINC01621 - ELOVL4	ENSG00000235357	ENSG00000118402	NA	48160	33268	rs2117445-G	rs2117445	0	2117445	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	(daytime napping, weekdays)	0.5066	[0.29-0.72] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	7p22.2	7	2884448	CARD11, GNA12, AMZ1, TTYH3	GNA12 - CARD11	ENSG00000146535	ENSG00000198286	NA	40140	21694	rs4557589-T	rs4557589	0	4557589	intergenic_variant	TRUE	NR	5e-6	5.301029995663981	(daytime napping, weekdays)	0.5071	[0.29-0.73] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	8q22.1	8	95608940	KB-1047C11.2	C8orf37-AS1	NA	NA	ENSG00000253773	NA	NA	rs3104888-T	rs3104888	0	3104888	intron_variant	FALSE	NR	3e-6	5.522878745280337	(daytime napping duration, weekdays)	0.1116	[0.065-0.159] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	18q21.32	18	60558794	AC010928.1, MRPS5P4, MC4R	MRPS5P4 - NA	ENSG00000266915	NA	NA	38629	NA	rs560248-A	rs560248	0	560248	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(daytime napping, weekdays)	0.5294	[0.31-0.75] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	16q23.3	16	82443709	CDH13	NA	NA	NA	NA	NA	NA	rs1364247-C	rs1364247	0	1364247	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	(daytime napping duration, weekdays)	0.08301	[0.048-0.118] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	1q31.1	1	189349198	NA	RN7SL261P - NA	ENSG00000277762	NA	NA	41659661	NA	rs7539118-G	rs7539118	0	7539118	intergenic_variant	TRUE	NR	6e-6	5.221848749616356	(daytime napping duration)	0.244	[0.14-0.35] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	1q31.2	1	193793599	RPL23AP22	RPL23AP22 - NA	ENSG00000237213	NA	NA	36332	NA	rs113943039-G	rs113943039	0	113943039	intron_variant	TRUE	NR	1e-6	6	(daytime napping duration)	0.2695	[0.16-0.38] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	1q44	1	245330850	KIF26B, EFCAB2	KIF26B	NA	NA	ENSG00000162849	NA	NA	rs34130928-G	rs34130928	0	34130928	intron_variant	FALSE	NR	3e-6	5.522878745280337	(daytime napping duration)	0.1148	[0.066-0.163] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	3p24.3	3	22562966	HMGB1P5, ZNF385D	NA	NA	NA	NA	NA	NA	rs4858419-T	rs4858419	0	4858419	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	(daytime napping duration)	0.09356	[0.058-0.129] unit decrease	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-03-21	27671213	Petros Z	2016-09-26	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/27671213	Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity.	Liver injury in anti-tuberculosis drug treatment	48 Ethiopian cases with liver injury, 354 Ethiopian cases without liver injury	27 Ethiopian cases with liver injury, 217 Ethiopian cases without liver injury	6p22.3	6	24967012	FAM65B	RIPOR2	NA	NA	ENSG00000111913	NA	NA	rs10946737-A	rs10946737	0	10946737	intron_variant	FALSE	NR	4e-6	5.3979400086720375	NA	3.4	[2.2-5.3]	Illumina [660206]	N	response to rifampicin, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007866, http://www.ebi.ac.uk/efo/EFO_0004228	GCST003792	Genome-wide genotyping array	NA	3.4	NA
2017-03-21	27671213	Petros Z	2016-09-26	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/27671213	Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity.	Liver injury in anti-tuberculosis drug treatment	48 Ethiopian cases with liver injury, 354 Ethiopian cases without liver injury	27 Ethiopian cases with liver injury, 217 Ethiopian cases without liver injury	1p33	1	48623525	AGBL4	AGBL4	NA	NA	ENSG00000186094	NA	NA	rs320035-G	rs320035	0	320035	intron_variant	FALSE	NR	5e-6	5.301029995663981	NA	2.3	[1.6-3.3]	Illumina [660206]	N	response to rifampicin, drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0007866, http://www.ebi.ac.uk/efo/EFO_0004228	GCST003792	Genome-wide genotyping array	NA	2.3	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	5q13.2	5	72432861	intergenic	YBX1P5 - ZNF366	ENSG00000251108	ENSG00000178175	NA	14526	7042	rs2338224-G	rs2338224	0	2338224	intergenic_variant	TRUE	0.8787	1e-14	14	NA	0.0425276	[0.032-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.8787	NA	0.0425276
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	5q31.1	5	132341949	AC034220.3, SLC22A4	MIR3936HG, SLC22A4	NA	NA	ENSG00000233006, ENSG00000197208	NA	NA	rs10075801-G	rs10075801	0	10075801	intron_variant	FALSE	0.4855	8e-23	22.096910013008056	NA	0.03571686	[0.029-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4855	NA	0.03571686
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	5q31.3	5	142130697	NDFIP1	NDFIP1	NA	NA	ENSG00000131507	NA	NA	rs11405616-CA	rs11405616	0	11405616	intron_variant	FALSE	0.6035	1e-17	17	NA	0.031876	[0.025-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.6035	NA	0.031876
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	5q32	5	148820990	intergenic	HTR4 - ADRB2	ENSG00000164270	ENSG00000169252	NA	143755	5621	rs2082382-A	rs2082382	0	2082382	regulatory_region_variant	TRUE	0.5468	1e-18	18	NA	0.03204283	[0.025-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5468	NA	0.03204283
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	5q35.2	5	173778222	intergenic	LINC01484 - LINC01485	ENSG00000253686	ENSG00000254211	NA	31943	305	rs791357-C	rs791357	0	791357	intergenic_variant	TRUE	0.7204	6e-24	23.221848749616356	NA	0.04104193	[0.033-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.7204	NA	0.04104193
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	5q35.3	5	179757487	MAML1	MAML1, MAML1	NA	NA	ENSG00000283780, ENSG00000161021	NA	NA	rs76025697-A	rs76025697	0	76025697	intron_variant	FALSE	0.4196	6e-12	11.221848749616356	NA	0.02506105	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4196	NA	0.02506105
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6p22.3	6	16744456	ATXN1	ATXN1	NA	NA	ENSG00000124788	NA	NA	rs1144700-T	rs1144700	0	1144700	intron_variant	FALSE	0.1789	8e-13	12.096910013008056	NA	0.03386698	[0.025-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.1789	NA	0.03386698
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6p22.3	6	21381296	intergenic	NA	NA	NA	NA	NA	NA	rs6917586-A	rs6917586	0	6917586	intron_variant	TRUE	0.3569	2e-11	10.698970004336019	NA	0.02532662	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3569	NA	0.02532662
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6p22.3	6	22359286	intergenic	CASC15	NA	NA	ENSG00000272168	NA	NA	rs113977268-A	rs113977268	0	113977268	intron_variant	FALSE	0.0859	5e-9	8.301029995663981	NA	0.03738569	[0.025-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0859	NA	0.03738569
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6p22.1	6	29955314	HLA-W	HLA-A - HLA-W	ENSG00000235657	ENSG00000235144	NA	9430	1282	rs9260620-G	rs9260620	0	9260620	intron_variant	TRUE	0.3358	7e-45	44.15490195998574	NA	0.05377813	[0.046-0.061] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3358	NA	0.05377813
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6p21.33	6	31274397	HLA-C, USP8P1	HLA-C - USP8P1	ENSG00000228299	ENSG00000236374	NA	2267	1175	rs2524079-A	rs2524079	0	2524079	intron_variant	TRUE	0.4168	9e-69	68.04575749056067	NA	0.06375719	[0.057-0.071] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4168	NA	0.06375719
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6p21.32	6	32623176	intergenic	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735	NA	33328	5003	rs9271588-C	rs9271588	0	9271588	intergenic_variant	TRUE	0.5051	2e-66	65.69897000433602	NA	0.06164672	[0.055-0.069] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5051	NA	0.06164672
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6q14.3	6	87128241	intergenic	RCN1P1 - ZNF292	ENSG00000215477	ENSG00000188994	NA	5553	24592	rs200638392-T	rs200638392	0	200638392	intergenic_variant	TRUE	0.4161	2e-15	14.698970004336019	NA	0.03037785	[0.023-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4161	NA	0.03037785
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6q21	6	109286353	RP11-425D10.1, CCDC162P	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs9400271-A	rs9400271	0	9400271	non_coding_transcript_exon_variant	FALSE	0.4836	5e-22	21.30102999566398	NA	0.03462562	[0.028-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4836	NA	0.03462562
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6q23.3	6	135099930	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs34208856-C	rs34208856	0	34208856	intron_variant	FALSE	0.2696	2e-18	17.69897000433602	NA	0.03593464	[0.028-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.2696	NA	0.03593464
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6q23.3	6	135328483	AHI1	AHI1	NA	NA	ENSG00000135541	NA	NA	rs146318841-G	rs146318841	1	59395091	intron_variant	FALSE	0.5243	3e-14	13.522878745280337	NA	0.02734774	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5243	NA	0.02734774
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	6q25.3	6	159049026	RP1-111C20.4	TAGAP-AS1	NA	NA	ENSG00000271913	NA	NA	rs212409-A	rs212409	0	212409	intron_variant	FALSE	0.5529	2e-12	11.698970004336019	NA	0.02546645	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5529	NA	0.02546645
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	7p21.3	7	7978549	GLCCI1, RPA3-AS1	GLCCI1	NA	NA	ENSG00000106415	NA	NA	rs7804306-A	rs7804306	0	7804306	intron_variant	FALSE	0.0606	3e-9	8.522878745280337	NA	0.04498851	[0.03-0.06] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0606	NA	0.04498851
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	7p15.1	7	28237488	JAZF1-AS1	JAZF1-AS1	NA	NA	ENSG00000234336	NA	NA	rs2158799-G	rs2158799	0	2158799	intron_variant	FALSE	0.6082	6e-49	48.221848749616356	NA	0.05460752	[0.047-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.6082	NA	0.05460752
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	7p15.1	7	28684757	CREB5	CREB5	NA	NA	ENSG00000146592	NA	NA	rs56388170-T	rs56388170	0	56388170	intron_variant	FALSE	0.2958	6e-78	77.22184874961636	NA	0.07457882	[0.067-0.082] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.2958	NA	0.07457882
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	7p13	7	44969742	MYO1G	MYO1G	NA	NA	ENSG00000136286	NA	NA	rs3735485-G	rs3735485	0	3735485	missense_variant	FALSE	0.8456	3e-11	10.522878745280337	NA	0.03290478	[0.023-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.8456	NA	0.03290478
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	7p12.3	7	47408324	TNS3	TNS3	NA	NA	ENSG00000136205	NA	NA	rs834603-G	rs834603	0	834603	intron_variant	FALSE	0.4909	4e-9	8.397940008672037	NA	0.02124128	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4909	NA	0.02124128
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	7p12.2	7	50218107	intergenic	SPATA48 - IKZF1	ENSG00000164500	ENSG00000185811	NA	58851	85961	rs11769630-A	rs11769630	0	11769630	intron_variant	TRUE	0.0748	4e-9	8.397940008672037	NA	0.04102118	[0.027-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0748	NA	0.04102118
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	7q21.2	7	92606850	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs8179-C	rs8179	0	8179	3_prime_UTR_variant	FALSE	0.7916	3e-20	19.522878745280337	NA	0.04091125	[0.032-0.05] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.7916	NA	0.04091125
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	7q21.2	7	92779056	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs445-T	rs445	0	445	intron_variant	FALSE	0.0971	2e-65	64.69897000433602	NA	0.1038414	[0.092-0.116] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0971	NA	0.1038414
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8p23.1	8	10848901	RP11-177H2.2	PINX1 - XKR6	ENSG00000258724	ENSG00000171044	NA	9054	47144	rs1991651-G	rs1991651	0	1991651	intergenic_variant	TRUE	0.6178	1e-12	12	NA	0.02628387	[0.019-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.6178	NA	0.02628387
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8p21.3	8	23109256	TNFRSF10C	TNFRSF10C	NA	NA	ENSG00000173535	NA	NA	rs12550612-A	rs12550612	0	12550612	intron_variant	FALSE	0.8225	3e-12	11.522878745280337	NA	0.03288693	[0.024-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.8225	NA	0.03288693
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8p12	8	30423317	RBPMS	RBPMS	NA	NA	ENSG00000157110	NA	NA	rs2979489-A	rs2979489	0	2979489	intron_variant	FALSE	0.7425	1e-12	12	NA	0.02919017	[0.021-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.7425	NA	0.02919017
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8q12.1	8	55878685	LYN	TGS1 - LYN	ENSG00000137574	ENSG00000254087	NA	52240	1150	rs2271400-T	rs2271400	0	2271400	regulatory_region_variant	TRUE	0.687	3e-10	9.522878745280337	NA	0.02442228	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.687	NA	0.02442228
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8q12.2	8	60738272	CHD7	CHD7	NA	NA	ENSG00000171316	NA	NA	rs7846314-T	rs7846314	0	7846314	intron_variant	FALSE	0.1866	2e-38	37.69897000433602	NA	0.05996328	[0.051-0.069] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.1866	NA	0.05996328
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8q13.2	8	67900953	intergenic	NDUFS5P6 - PREX2	ENSG00000255531	ENSG00000046889	NA	51615	51093	rs12542907-G	rs12542907	0	12542907	intergenic_variant	TRUE	0.402	6e-12	11.221848749616356	NA	0.02526099	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.402	NA	0.02526099
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8q22.3	8	102840179	AZIN1	AZIN1	NA	NA	ENSG00000155096	NA	NA	rs2436845-A	rs2436845	0	2436845	intron_variant	FALSE	0.4343	1e-9	9	NA	0.02223366	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4343	NA	0.02223366
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8q24.13	8	125479491	RP11-136O12.2	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	41088	380230	rs2954031-T	rs2954031	0	2954031	intron_variant	TRUE	0.4452	2e-10	9.698970004336019	NA	0.02300901	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4452	NA	0.02300901
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8q24.21	8	129599504	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs397731840-CT	rs397731840	1	60379390	intron_variant	FALSE	0.5942	3e-26	25.522878745280337	NA	0.0409617	[0.033-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5942	NA	0.0409617
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8q24.21	8	129612570	CCDC26	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs1982094-T	rs1982094	0	1982094	intron_variant	FALSE	0.0424	4e-16	15.397940008672037	NA	0.07377733	[0.056-0.092] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0424	NA	0.07377733
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	8q24.3	8	141327691	RP11-10J21.6	SLC45A4 - LINC01300	ENSG00000022567	ENSG00000253595	NA	19386	12814	rs6986779-T	rs6986779	0	6986779	regulatory_region_variant	TRUE	0.3592	6e-15	14.221848749616356	NA	0.02929508	[0.022-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3592	NA	0.02929508
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	9p24.3	9	305428	DOCK8	DOCK8	NA	NA	ENSG00000107099	NA	NA	rs1969949-G	rs1969949	0	1969949	intron_variant	FALSE	0.7214	3e-11	10.522878745280337	NA	0.02690919	[0.019-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.7214	NA	0.02690919
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	9p24.1	9	4763176	intergenic	AK3 - ECM1P1	ENSG00000147853	ENSG00000270639	NA	21133	5441	rs385893-C	rs385893	0	385893	regulatory_region_variant	TRUE	0.5221	1e-14	14	NA	0.02762743	[0.021-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5221	NA	0.02762743
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	9q34.13	9	132989126	GFI1B	GFI1B	NA	NA	ENSG00000165702	NA	NA	rs150813342-T	rs150813342	0	150813342	synonymous_variant	FALSE	0.0084	7e-11	10.154901959985743	NA	0.1328551	[0.093-0.173] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.0084	NA	0.1328551
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	9q34.2	9	133279427	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	3403	58301	rs635634-T	rs635634	0	635634	intergenic_variant	TRUE	0.1824	5e-20	19.30102999566398	NA	0.04251764	[0.033-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.1824	NA	0.04251764
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	9q34.3	9	136427805	INPP5E, PMPCA	PMPCA - INPP5E	ENSG00000165688	ENSG00000148384	NA	4044	814	rs71191701-C	rs71191701	0	71191701	intergenic_variant	TRUE	0.2916	3e-17	16.522878745280337	NA	0.03321731	[0.025-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.2916	NA	0.03321731
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	10p12.1	10	24922362	PRTFDC1	PRTFDC1	NA	NA	ENSG00000099256	NA	NA	rs12266014-T	rs12266014	0	12266014	intron_variant	FALSE	0.3687	2e-32	31.69897000433602	NA	0.04417048	[0.037-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.36870000000000003	NA	0.04417048
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	10p12.1	10	28491444	RP11-351M16.3	LINC02652	NA	NA	ENSG00000237128	NA	NA	rs2998286-C	rs2998286	0	2998286	intron_variant	FALSE	0.7694	2e-23	22.69897000433602	NA	0.04277287	[0.034-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.7694	NA	0.04277287
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	NA	NA	NA	CXCL12	NA	NA	NA	NA	NA	NA	chr10:44872361-TAA	chr10:44872361	0	NA	NA	TRUE	0.3029	8e-10	9.096910013008056	NA	0.02452283	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3029	NA	0.02452283
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	10q21.3	10	63250912	JMJD1C	JMJD1C	NA	NA	ENSG00000171988	NA	NA	rs10995477-C	rs10995477	0	10995477	intron_variant	FALSE	0.4722	5e-22	21.30102999566398	NA	0.03472657	[0.028-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4722	NA	0.03472657
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	10q22.3	10	79287818	ZMIZ1	ZMIZ1	NA	NA	ENSG00000108175	NA	NA	rs2802372-C	rs2802372	0	2802372	intron_variant	FALSE	0.4345	7e-9	8.154901959985743	NA	0.021148	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.4345	NA	0.021148
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	10q24.1	10	97314230	RP11-452K12.3	RPL12P27 - FRAT1	ENSG00000237169	ENSG00000165879	NA	4272	5041	rs397933924-CCAGGTTCAAGCGAT	rs397933924	0	397933924	intergenic_variant	TRUE	0.5821	4e-38	37.39794000867204	NA	0.0476573	[0.04-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.5821	NA	0.0476573
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	11p15.5	11	308314	IFITM2	IFITM2	NA	NA	ENSG00000185201	NA	NA	rs14408-C	rs14408	0	14408	missense_variant	FALSE	0.3668	8e-48	47.096910013008056	NA	0.05469992	[0.047-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3668	NA	0.05469992
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	11p11.2	11	47927817	intergenic	NUP160 - PTPRJ	ENSG00000030066	ENSG00000149177	NA	79262	52741	rs552557467-C	rs552557467	0	552557467	regulatory_region_variant	TRUE	0.672	9e-10	9.045757490560675	NA	0.02467009	[0.017-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.672	NA	0.02467009
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Granulocyte count	169,822 European ancestry individuals	NA	11q12.2	11	61812288	FADS1, FADS2	FADS1, FADS2	NA	NA	ENSG00000149485, ENSG00000134824	NA	NA	rs174555-C	rs174555	0	174555	intron_variant	FALSE	0.3085	7e-14	13.154901959985743	NA	0.02905092	[0.021-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	granulocyte count	http://www.ebi.ac.uk/efo/EFO_0007987	GCST004614	Genome-wide genotyping array	0.3085	NA	0.02905092
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	2p11.2	2	86244991	REEP1, MRPL35, IMMT, MIR4779	REEP1	NA	NA	ENSG00000068615	NA	NA	rs35160687-T	rs35160687	0	35160687	intron_variant	FALSE	NR	5e-6	5.301029995663981	(sleep onset)	0.1859	[0.11-0.27] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6q22.31	6	125468501	HDDC2, TPD52L1	NA - PRKN	NA	ENSG00000185345	NA	NA	35878916	rs34172167-T	rs34172167	0	34172167	intergenic_variant	TRUE	NR	9e-6	5.045757490560675	(sleep onset)	0.2146	[0.12-0.31] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6q22.33	6	129400338	LAMA2, ARHGAP18, BMPR1APS1	LAMA2	NA	NA	ENSG00000196569	NA	NA	rs2326816-C	rs2326816	0	2326816	intron_variant	FALSE	NR	6e-6	5.221848749616356	(sleep onset)	0.1914	[0.11-0.27] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	RP11-282I1.1, GPR26	NA	NA	NA	NA	NA	NA	chr10:125204062-A	chr10:125204062	0	NA	NA	TRUE	NR	9e-6	5.045757490560675	(sleep onset)	0.1949	[0.11-0.28] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	12q23.3	12	105709790	RP11-266E14.1	CASC18	NA	NA	ENSG00000257859	NA	NA	rs3863381-G	rs3863381	0	3863381	intron_variant	FALSE	NR	7e-6	5.154901959985743	(sleep onset)	0.2571	[0.15-0.37] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	15q26.1	15	88621800	AEN, MIR7-2, MIR1179, ISG20	AEN	NA	NA	ENSG00000181026	NA	NA	rs8024058-A	rs8024058	0	8024058	splice_region_variant	FALSE	NR	9e-6	5.045757490560675	(sleep onset)	0.2095	[0.12-0.3] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	15q26.2	15	97171304	NA	NA - LINC02253	NA	ENSG00000259485	NA	NA	44508	rs12441664-T	rs12441664	0	12441664	intergenic_variant	TRUE	NR	8e-8	7.096910013008056	(sleep onset)	0.2782	[0.18-0.38] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	17q12	17	34833416	RP11-642M2.1, CCT6B, ZNF830, LIG3	ARHGAP44 - CCT6B	ENSG00000006740	ENSG00000132141	NA	21841773	94443	rs7218593-T	rs7218593	0	7218593	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	(sleep onset)	0.3163	[0.2-0.44] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	17q12	17	34939412	CCT6B, ZNF830, LIG3, RFFL	CCT6B	NA	NA	ENSG00000132141	NA	NA	rs12452225-C	rs12452225	0	12452225	non_coding_transcript_exon_variant	FALSE	NR	4e-7	6.3979400086720375	(sleep onset)	0.3253	[0.2-0.45] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	20p12.2	20	11596657	PGAM3P, LINC00687	NA - PGAM3P	NA	ENSG00000237256	NA	NA	24394	rs113179280-T	rs113179280	0	113179280	intergenic_variant	TRUE	NR	5e-6	5.301029995663981	(sleep onset)	0.4007	[0.23-0.57] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1q23.3	1	161056700	ARHGAP30, USF1, PVRL4, F11R, TSTD1, KLHDC9	ARHGAP30	NA	NA	ENSG00000186517	NA	NA	rs12130871-G	rs12130871	0	12130871	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(sleep onset, weekdays)	0.2138	[0.12-0.3] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	2p16.2	2	53086330	NA	NA	NA	NA	NA	NA	NA	rs73933942-C	rs73933942	0	73933942	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	(sleep onset, weekdays)	0.4007	[0.25-0.55] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q11.2	5	53873690	ARL15, ASS1P9, MIR581, NDUFS4	ASS1P9 - ARL15	ENSG00000217791	ENSG00000185305	NA	13289	10252	rs702612-A	rs702612	0	702612	regulatory_region_variant	TRUE	NR	1e-6	6	(sleep onset, weekdays)	0.4556	[0.27-0.64] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q22.3	5	114242610	KCNN2	KCNN2	NA	NA	ENSG00000080709	NA	NA	rs10065369-T	rs10065369	0	10065369	intron_variant	FALSE	NR	7e-6	5.154901959985743	(sleep onset, weekdays)	0.2506	[0.14-0.36] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q31.3	5	143278591	NR3C1, ARHGAP26, ARHGAP26-IT1	NR3C1	NA	NA	ENSG00000113580	NA	NA	rs6191-A	rs6191	0	6191	3_prime_UTR_variant	FALSE	NR	8e-6	5.096910013008056	(sleep onset, weekdays)	0.1867	[0.1-0.27] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6p25.2	6	4057804	PRPF4B, FAM217A, C6orf201, ECI2	FAM217A, PRPF4B	NA	NA	ENSG00000145975, ENSG00000112739	NA	NA	rs853410-G	rs853410	0	853410	intron_variant	FALSE	NR	9e-6	5.045757490560675	(sleep onset, weekdays)	0.3658	[0.2-0.53] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6p21.33	6	31151126	CCHCR1, TCF19, POLR2LP, PSORS1C1, POU5F1, PSORS1C2	CCHCR1, CCHCR1, CCHCR1, CCHCR1, CCHCR1, CCHCR1	NA	NA	ENSG00000204536, ENSG00000223533, ENSG00000206457, ENSG00000206355, ENSG00000224180, ENSG00000234114	NA	NA	rs115235267-T	rs115235267	1	74705176	splice_region_variant	FALSE	NR	5e-6	5.301029995663981	(sleep onset, weekdays)	0.6313	[0.36-0.9] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	7q31.1	7	110436083	AC003088.1, IMMP2L	NA	NA	NA	NA	NA	NA	rs211800-G	rs211800	0	211800	intron_variant	TRUE	NR	3e-6	5.522878745280337	(sleep onset, weekdays)	0.1994	[0.12-0.28] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	FAR1, RPL39P26, FAR1-IT1, HMGN2P36	NA	NA	NA	NA	NA	NA	chr11:13730898-T	chr11:13730898	0	NA	NA	TRUE	NR	2e-6	5.698970004336019	(sleep onset, weekdays)	0.4561	[0.27-0.64] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	13q34	13	110177535	COL4A1, COL4A2	COL4A1	NA	NA	ENSG00000187498	NA	NA	rs71440053-T	rs71440053	0	71440053	intron_variant	FALSE	NR	1e-6	6	(sleep onset, weekdays)	0.5621	[0.33-0.79] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	16q23.3	16	83413666	CDH13, MIR3182	CDH13	NA	NA	ENSG00000140945	NA	NA	rs74249525-T	rs74249525	0	74249525	intron_variant	FALSE	NR	6e-6	5.221848749616356	(sleep onset, weekdays)	0.5058	[0.29-0.73] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1p32.1	1	60083387	C1orf87, PGBD4P8, CYP2J2, HOOK1	C1orf87 - PGBD4P8	ENSG00000162598	ENSG00000229332	NA	9617	14028	rs3958719-T	rs3958719	0	3958719	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(sleep onset irregularity)	0.05958	[0.035-0.084] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1q42.3	1	235013514	TOMM20, SNORA14B, RBM34, ARID4B	NA - LINC01348	NA	ENSG00000280587	NA	NA	51965	rs57941271-A	rs57941271	0	57941271	intergenic_variant	TRUE	NR	8e-7	6.096910013008056	(sleep onset irregularity)	0.07764	[0.047-0.109] unit increase	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q13.3	5	74391461	CTC-419K13.1, ENC1, HEXB	LINC01331	NA	NA	ENSG00000248673	NA	NA	rs76768179-G	rs76768179	0	76768179	intron_variant	FALSE	NR	8e-6	5.096910013008056	(sleep onset irregularity)	0.1142	[0.064-0.164] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6q22.31	6	123877771	NKAIN2, TRDN	NKAIN2	NA	NA	ENSG00000188580	NA	NA	rs55902602-T	rs55902602	0	55902602	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(sleep onset irregularity)	0.06737	[0.039-0.096] unit increase	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1p32.1	1	58876993	RP4-794H19.2, JUN, PHBP3, MYSM1	LINC01135	NA	NA	ENSG00000234807	NA	NA	rs2764894-A	rs2764894	0	2764894	intron_variant	FALSE	NR	8e-6	5.096910013008056	(sleep offset)	0.1815	[0.1-0.26] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1p21.3	1	98597446	SNX7	NA - SNX7	NA	ENSG00000162627	NA	NA	64255	rs115578460-T	rs115578460	0	115578460	intergenic_variant	TRUE	NR	1e-7	7	(sleep offset)	0.6166	[0.39-0.84] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1p21.3	1	98997654	LPPR5, SNX7	PLPPR5	NA	NA	ENSG00000117598	NA	NA	rs79746559-A	rs79746559	0	79746559	intron_variant	FALSE	NR	8e-7	6.096910013008056	(sleep offset)	0.6146	[0.37-0.86] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	2p11.2	2	88105028	SMYD1, FABP1, MIR4780, KRCC1	SMYD1	NA	NA	ENSG00000115593	NA	NA	rs2919869-G	rs2919869	0	2919869	intron_variant	FALSE	NR	3e-8	7.522878745280337	(sleep offset)	0.2722	[0.18-0.37] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	LINC00690, DAZL, RFTN1, OXNAD1	NA	NA	NA	NA	NA	NA	chr3:16598327-CT	chr3:16598327	0	NA	NA	TRUE	NR	2e-6	5.698970004336019	(sleep offset)	0.2868	[0.17-0.4] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	4q24	4	106012900	RP11-710F7.3, NPNT, TBCK, INTS12	NPNT - TBCK	ENSG00000168743	ENSG00000145348	NA	8873	28699	rs143750764-T	rs143750764	0	143750764	intron_variant	TRUE	NR	4e-6	5.3979400086720375	(sleep offset)	0.6222	[0.36-0.89] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	7p15.3	7	22395855	STEAP1B, RAPGEF5, RNA5SP227, EEF1A1P6	RAPGEF5 - STEAP1B	ENSG00000136237	ENSG00000105889	NA	38701	23589	rs34349384-T	rs34349384	0	34349384	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(sleep offset)	0.2282	[0.13-0.32] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	8q24.13	8	121938639	MRPS36P3	HAS2-AS1	NA	NA	ENSG00000248690	NA	NA	rs75545078-C	rs75545078	0	75545078	intron_variant	FALSE	NR	1e-6	6	(sleep offset)	0.3947	[0.24-0.55] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	chr10:57778684-G	chr10:57778684	0	NA	NA	TRUE	NR	4e-6	5.3979400086720375	(sleep offset)	0.2345	[0.13-0.33] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	11q22.2	11	102609659	MMP20, RP11-817J15.2, MMP7, MMP27	MMP20	NA	NA	ENSG00000137674	NA	NA	rs17098961-A	rs17098961	0	17098961	intron_variant	FALSE	NR	7e-7	6.154901959985743	(sleep offset)	0.7711	[0.47-1.08] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	15q22.2	15	60140722	FOXB1, MESTP2, ANXA2	FOXB1 - NA	ENSG00000171956	NA	NA	78992	NA	rs147577476-G	rs147577476	0	147577476	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(sleep offset)	0.6396	[0.37-0.91] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	20p12.1	20	13287360	ISM1, TASP1, ISM1-AS1, GAPDHP2	ISM1	NA	NA	ENSG00000101230	NA	NA	rs76783882-G	rs76783882	1	6033658	intron_variant	FALSE	NR	8e-7	6.096910013008056	(sleep offset)	0.2043	[0.12-0.29] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1q23.3	1	164847489	PBX1	PBX1	NA	NA	ENSG00000185630	NA	NA	rs6426881-T	rs6426881	0	6426881	3_prime_UTR_variant	FALSE	NR	8e-6	5.096910013008056	(sleep offset, weekdays)	0.2486	[0.14-0.36] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3p26.3	3	1922955	RPL21P17, CNTN4, CNTN4-AS2	RPL21P17 - TRAIP	ENSG00000214073	ENSG00000183763	NA	16830	47905646	rs11718454-T	rs11718454	0	11718454	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	(sleep offset, weekdays)	0.6609	[0.38-0.94] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3p14.3	3	54855753	CACNA2D3, CACNA2D3-AS1, LRTM1, ESRG	CACNA2D3	NA	NA	ENSG00000157445	NA	NA	rs1168696-C	rs1168696	0	1168696	intron_variant	FALSE	NR	6e-6	5.221848749616356	(sleep offset, weekdays)	0.2448	[0.14-0.35] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	RPL21P41, KBTBD8	NA	NA	NA	NA	NA	NA	chr3:66802684-CT	chr3:66802684	0	NA	NA	TRUE	NR	4e-6	5.3979400086720375	(sleep offset, weekdays)	0.3255	[0.19-0.46] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	chr3:176099472-TAGAC	chr3:176099472	0	NA	NA	TRUE	NR	2e-6	5.698970004336019	(sleep offset, weekdays)	0.3217	[0.19-0.46] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	7p21.1	7	18808911	HDAC9, 7SK, NPM1P13, TWIST1	HDAC9	NA	NA	ENSG00000048052	NA	NA	rs7794273-G	rs7794273	0	7794273	intron_variant	FALSE	NR	3e-6	5.522878745280337	(sleep offset, weekdays)	0.216	[0.13-0.31] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	7q21.11	7	78052062	MAGI2, PHTF2	MAGI2	NA	NA	ENSG00000187391	NA	NA	rs10236696-G	rs10236696	0	10236696	intron_variant	FALSE	NR	8e-6	5.096910013008056	(sleep offset, weekdays)	0.2551	[0.14-0.37] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	7q22.1	7	104006897	RELN, ORC5	RELN - NA	ENSG00000189056	NA	NA	17239	NA	rs62485867-A	rs62485867	0	62485867	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(sleep offset, weekdays)	0.3091	[0.18-0.44] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	9p24.3	9	1076640	DMRT2, DMRT3, DMRT1	DMRT2 - RPS27AP14	ENSG00000173253	ENSG00000236594	NA	19088	87774	rs13284938-A	rs13284938	0	13284938	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	(sleep offset, weekdays)	0.2755	[0.16-0.39] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	CLSTN3, RBP5, C1RL-AS1, C1RL, PEX5	NA	NA	NA	NA	NA	NA	chr12:7297418-ATT	chr12:7297418	0	NA	NA	TRUE	NR	5e-6	5.301029995663981	(sleep offset, weekdays)	0.2309	[0.13-0.33] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	18q22.2	18	70402035	RPS2P6, SOCS6, RTTN	LINC01910 - LARP7P3	ENSG00000266278	ENSG00000265698	NA	17444	10020	rs117535166-G	rs117535166	0	117535166	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	(sleep offset, weekdays)	0.4726	[0.27-0.68] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	19q13.32	19	46450125	PNMAL1, PPP5D1, CCDC8, PNMAL2	PNMA8C - PNMA8A	ENSG00000277531	ENSG00000182013	NA	21189	16366	rs10409958-A	rs10409958	0	10409958	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(sleep offset, weekdays)	0.5573	[0.32-0.79] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	20q13.33	20	61429112	CDH4	CDH4, CDH4	NA	NA	ENSG00000179242, ENSG00000280641	NA	NA	rs1892312-G	rs1892312	0	1892312	intron_variant	FALSE	NR	9e-6	5.045757490560675	(sleep offset, weekdays)	0.3914	[0.22-0.56] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-03-31	28171582	Gao X	2016-11-15	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28171582	Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos.	Central corneal thickness	3,584 Latino individuals	931 Latino individuals	9q34.3	9	134544468	RXRA, COL5A1, LOC100506532	NA - COL5A1	NA	ENSG00000130635	NA	NA	97335	rs3118515-A	rs3118515	0	3118515	intron_variant	TRUE	0.268	9e-11	10.045757490560675	NA	5.15	[NR] unit decrease (initial cohort)	Illumina [576798] (imputed)	N	central corneal thickness	http://www.ebi.ac.uk/efo/EFO_0005213	GCST003856	Genome-wide genotyping array	0.268	5.15	NA
2017-03-31	28171582	Gao X	2016-11-15	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28171582	Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos.	Central corneal thickness	3,584 Latino individuals	931 Latino individuals	16q24.2	16	88264518	ZNF469, BANP	LINC02182 - NA	ENSG00000260420	NA	NA	69301	NA	rs12447690-C	rs12447690	0	12447690	intron_variant	TRUE	0.36	2e-8	7.698970004336019	NA	4.86	[NR] unit decrease (initial cohort)	Illumina [576798] (imputed)	N	central corneal thickness	http://www.ebi.ac.uk/efo/EFO_0005213	GCST003856	Genome-wide genotyping array	0.36	4.86	NA
2017-03-31	28171582	Gao X	2016-11-15	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28171582	Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos.	Central corneal thickness	3,584 Latino individuals	931 Latino individuals	22q13.31	22	45967859	WNT7B	WNT7B	NA	NA	ENSG00000188064	NA	NA	rs10453441-G	rs10453441	0	10453441	intron_variant	FALSE	0.455	6e-9	8.221848749616356	NA	4.51	[NR] unit decrease (initial cohort)	Illumina [576798] (imputed)	N	central corneal thickness	http://www.ebi.ac.uk/efo/EFO_0005213	GCST003856	Genome-wide genotyping array	0.455	4.51	NA
2017-03-31	28171582	Gao X	2016-11-15	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28171582	Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos.	Central corneal thickness	3,584 Latino individuals	931 Latino individuals	9q34.3	9	134540402	RXRA, COL5A1	RXRA - NA	ENSG00000186350	NA	NA	99817	NA	rs1536478-G	rs1536478	0	1536478	intron_variant	TRUE	0.47	2e-8	7.698970004336019	NA	4.17	[NR] unit decrease	Illumina [576798] (imputed)	N	central corneal thickness	http://www.ebi.ac.uk/efo/EFO_0005213	GCST003856	Genome-wide genotyping array	0.47	4.17	NA
2017-03-31	28171582	Gao X	2016-11-15	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28171582	Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos.	Central corneal thickness	3,584 Latino individuals	931 Latino individuals	16q24.2	16	88296907	ZNF469	NA - ZNF469	NA	ENSG00000225614	NA	NA	86052	rs12448211-A	rs12448211	0	12448211	intron_variant	TRUE	0.65	4e-8	7.3979400086720375	NA	4.51	[NR] unit increase	Illumina [576798] (imputed)	N	central corneal thickness	http://www.ebi.ac.uk/efo/EFO_0005213	GCST003856	Genome-wide genotyping array	0.65	4.51	NA
2017-03-31	28171582	Gao X	2016-11-15	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28171582	Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos.	Central corneal thickness	3,584 Latino individuals	931 Latino individuals	15q26.3	15	101045131	LRRK1	LRRK1	NA	NA	ENSG00000154237	NA	NA	rs4965359-A	rs4965359	0	4965359	intron_variant	FALSE	0.54	4e-7	6.3979400086720375	NA	3.77	[NR] unit decrease	Illumina [576798] (imputed)	N	central corneal thickness	http://www.ebi.ac.uk/efo/EFO_0005213	GCST003856	Genome-wide genotyping array	0.54	3.77	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	2p22.2	2	37376658	QPCT, PRKD3	QPCT - RNU6-1116P	ENSG00000115828	ENSG00000253078	NA	3336	58852	rs888096-A	rs888096	0	888096	intergenic_variant	TRUE	NR	5e-8	7.301029995663981	NA	1.15	[1.09-1.21]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.15	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	2q13	2	111074216	ACOXL, BCL2L11	MIR4435-2HG, ACOXL	NA	NA	ENSG00000172965, ENSG00000153093	NA	NA	rs58055674-C	rs58055674	0	58055674	intron_variant	FALSE	NR	2e-27	26.69897000433602	NA	1.41	[1.32-1.5]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.41	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	2q33.1	2	201159226	CASP10, CASP8	CFLAR	NA	NA	ENSG00000003402	NA	NA	rs7558911-A	rs7558911	0	7558911	intron_variant	FALSE	NR	5e-11	10.301029995663981	NA	1.18	[1.12-1.24]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.18	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	2q37.1	2	230289297	SP110, SP140	SP140	NA	NA	ENSG00000079263	NA	NA	rs34004493-G	rs34004493	0	34004493	intron_variant	FALSE	NR	4e-32	31.397940008672037	NA	1.39	[1.31-1.47]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.39	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	2q37.3	2	241355498	FARP2	SEPTIN2 - FARP2	ENSG00000168385	ENSG00000006607	NA	1471	787	rs3755397-G	rs3755397	0	3755397	regulatory_region_variant	TRUE	NR	9e-12	11.045757490560675	NA	1.32	[1.22-1.43]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.32	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	3p24.1	3	27736288	EOMES	EOMES - LINC01980	ENSG00000163508	ENSG00000225548	NA	13577	61264	rs9880772-A	rs9880772	0	9880772	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	NA	1.16	[1.11-1.22]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.16	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	4q25	4	108104709	LEF1	LEF1	NA	NA	ENSG00000138795	NA	NA	rs7690934-C	rs7690934	0	7690934	intron_variant	FALSE	NR	6e-9	8.221848749616356	NA	1.16	[1.11-1.22]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.16	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	5p15.33	5	1285859	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs7705526-A	rs7705526	0	7705526	intron_variant	FALSE	NR	6e-10	9.221848749616356	NA	1.18	[1.12-1.25]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.18	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	6p25.3	6	412802	IRF4	IRF4 - EXOC2	ENSG00000137265	ENSG00000112685	NA	1359	72352	rs9392504-A	rs9392504	0	9392504	regulatory_region_variant	TRUE	NR	1e-28	28	NA	1.33	[1.26-1.4]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.33	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	6p21.32	6	32610350	HLA	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735	NA	20502	17829	rs9271176-G	rs9271176	0	9271176	intergenic_variant	TRUE	NR	3e-20	19.522878745280337	NA	1.29	[1.22-1.36]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.29	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	7q31.33	7	124752458	POT1	GPR37	NA	NA	ENSG00000170775	NA	NA	rs2267708-T	rs2267708	0	2267708	intron_variant	FALSE	NR	9e-9	8.045757490560675	NA	1.16	[1.1-1.22]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.16	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	8q24.21	8	127188726	POU5F1B	CASC19, PCAT1	NA	NA	ENSG00000254166, ENSG00000253438	NA	NA	rs2466029-G	rs2466029	0	2466029	non_coding_transcript_exon_variant	FALSE	NR	7e-16	15.154901959985743	NA	1.23	[1.17-1.3]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.23	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	9p21.3	9	22206988	CDKN2B-AS1	CDKN2B-AS1 - DMRTA1	ENSG00000240498	ENSG00000176399	NA	78885	239836	rs1679013-C	rs1679013	0	1679013	intron_variant	TRUE	NR	2e-8	7.698970004336019	NA	1.16	[1.1-1.22]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.16	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	10q23.31	10	88992261	ACTA, FAS	FAS	NA	NA	ENSG00000026103	NA	NA	rs6586163-A	rs6586163	0	6586163	non_coding_transcript_exon_variant	FALSE	NR	1e-15	15	NA	1.23	[1.17-1.29]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.23	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	11p15.5	11	2300420	C11orf21, TSPAN32	C11orf21	NA	NA	ENSG00000110665	NA	NA	rs2651823-A	rs2651823	0	2651823	intron_variant	FALSE	NR	5e-11	10.301029995663981	NA	1.18	[1.13-1.25]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.18	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	11q24.1	11	123484683	SCN3B, GRAMD1B	GRAMD1B	NA	NA	ENSG00000023171	NA	NA	rs35923643-G	rs35923643	0	35923643	intron_variant	FALSE	NR	4e-58	57.39794000867204	NA	1.63	[1.53-1.72]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.63	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	12q24.13	12	112943571	OAS3	OAS3	NA	NA	ENSG00000111331	NA	NA	rs6489882-G	rs6489882	0	6489882	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	1.16	[1.1-1.22]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.16	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	15q15.1	15	40111456	BMF, BUB1B	BMF - BUB1B	ENSG00000104081	ENSG00000156970	NA	2564	49567	rs8024033-C	rs8024033	0	8024033	intergenic_variant	TRUE	NR	7e-19	18.154901959985743	NA	1.26	[1.2-1.32]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.26	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	15q23	15	69728186	RPLP1	DRAIC	NA	NA	ENSG00000245750	NA	NA	rs11637565-G	rs11637565	0	11637565	intron_variant	FALSE	NR	2e-31	30.69897000433602	NA	1.35	[1.28-1.42]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.35	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	16q24.1	16	85895015	IRF8	COX4I1 - IRF8	ENSG00000131143	ENSG00000140968	NA	87947	4147	rs391855-A	rs391855	0	391855	intergenic_variant	TRUE	NR	1e-28	28	NA	1.34	[1.27-1.41]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.34	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	18q21.33	18	63121512	BCL2	PHLPP1 - BCL2	ENSG00000081913	ENSG00000171791	NA	141079	1834	rs77551289-A	rs77551289	0	77551289	intergenic_variant	TRUE	NR	2e-11	10.698970004336019	NA	1.37	[1.25-1.5]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.37	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	19q13.32	19	46673495	PRKD2, STRN4	DACT3-AS1	NA	NA	ENSG00000245598	NA	NA	rs874460-C	rs874460	0	874460	non_coding_transcript_exon_variant	FALSE	NR	3e-8	7.522878745280337	NA	1.24	[1.15-1.34]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	NA	1.24	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	4q24	4	101819845	BANK1	BANK1	NA	NA	ENSG00000153064	NA	NA	rs71597109-C	rs71597109	0	71597109	intron_variant	FALSE	0.69	1e-10	10	NA	1.17	[1.11-1.22]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	0.69	1.17	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	1p36.11	1	23617245	MDS2	MDS2	NA	NA	ENSG00000197880	NA	NA	rs34676223-C	rs34676223	0	34676223	intron_variant	FALSE	0.71	5e-13	12.301029995663981	NA	1.19	[1.14-1.25]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	0.71	1.19	NA
2017-06-08	28165464	Law PJ	2017-02-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28165464	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.	Chronic lymphocytic leukemia	4,478 European ancestry cases and 13,213 European ancestry controls.	1,722 European ancestry cases and 4,385 European ancestry controls.	6p21.31	6	34648545	C6orf106	ILRUN	NA	NA	ENSG00000196821	NA	NA	rs3800461-C	rs3800461	0	3800461	intron_variant	FALSE	0.11	2e-8	7.698970004336019	NA	1.2	[1.13-1.28]	Affymetrix, Illumina [> 10000000] (imputed)	N	chronic lymphocytic leukemia	http://www.ebi.ac.uk/efo/EFO_0000095	GCST004146	Genome-wide genotyping array	0.11	1.2	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	17q24.2	17	69085137	ABCA6	ABCA6	NA	NA	ENSG00000154262	NA	NA	rs77542162-G	rs77542162	0	77542162	missense_variant	FALSE	0.0232	2e-16	15.698970004336019	NA	0.09860702	[0.075-0.122] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0232	NA	0.09860702
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	18q21.1	18	48936766	SMAD7	SMAD7	NA	NA	ENSG00000101665	NA	NA	rs2878889-G	rs2878889	0	2878889	intron_variant	FALSE	0.4468	9e-10	9.045757490560675	NA	0.02199812	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.4468	NA	0.02199812
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	NA	NA	NA	PTBP1	NA	NA	NA	NA	NA	NA	chr19:807442-C	chr19:807442	0	NA	NA	TRUE	0.6049	5e-14	13.301029995663981	NA	0.02737278	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.6049	NA	0.02737278
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	19p13.3	19	2161322	AP3D1	AP3D1	NA	NA	ENSG00000065000	NA	NA	rs57908212-C	rs57908212	0	57908212	intron_variant	FALSE	0.4748	3e-14	13.522878745280337	NA	0.02720681	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.4748	NA	0.02720681
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	19p13.3	19	4502189	HDGFRP2	HDGFL2, PLIN4	NA	NA	ENSG00000167674, ENSG00000167676	NA	NA	rs8887-C	rs8887	0	8887	3_prime_UTR_variant	FALSE	0.5712	3e-13	12.522878745280337	NA	0.02651948	[0.019-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5712	NA	0.02651948
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	19q13.12	19	35456988	intergenic	FFAR2 - KRTDAP	ENSG00000126262	ENSG00000188508	NA	5221	30336	rs2871993-A	rs2871993	0	2871993	intergenic_variant	TRUE	0.284	9e-11	10.045757490560675	NA	0.02590688	[0.018-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.284	NA	0.02590688
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	19q13.2	19	40799233	EGLN2	EGLN2, RAB4B-EGLN2	NA	NA	ENSG00000269858, ENSG00000171570	NA	NA	rs184088518-T	rs184088518	0	184088518	5_prime_UTR_variant	FALSE	0.0237	4e-16	15.397940008672037	NA	0.1005758	[0.076-0.125] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0237	NA	0.1005758
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	19q13.2	19	40800745	EGLN2	EGLN2, RAB4B-EGLN2	NA	NA	ENSG00000269858, ENSG00000171570	NA	NA	rs61750953-T	rs61750953	0	61750953	missense_variant	FALSE	0.0154	1e-9	9	NA	0.08824054	[0.06-0.117] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0154	NA	0.08824054
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	19q13.2	19	40818173	CTC-490E21.12	CYP2T1P - CYP2F2P	ENSG00000233622	ENSG00000237118	NA	6073	241	rs71358934-A	rs71358934	0	71358934	intron_variant	TRUE	0.3143	5e-11	10.301029995663981	NA	0.02579586	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.3143	NA	0.02579586
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	19q13.31	19	43774629	KCNN4	KCNN4	NA	NA	ENSG00000104783	NA	NA	rs563995-A	rs563995	0	563995	intron_variant	FALSE	0.2282	4e-9	8.397940008672037	NA	0.02525654	[0.017-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2282	NA	0.02525654
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	19q13.32	19	47069730	ZC3H4	ZC3H4	NA	NA	ENSG00000130749	NA	NA	rs2241388-C	rs2241388	0	2241388	intron_variant	FALSE	0.7223	3e-10	9.522878745280337	NA	0.02488376	[0.017-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.7223	NA	0.02488376
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	19q13.33	19	49548305	RCN3	RCN3 - NOSIP	ENSG00000142552	ENSG00000142546	NA	1343	7163	rs111476047-TTTGG	rs111476047	0	111476047	intergenic_variant	TRUE	0.202	1e-11	11	NA	0.03087733	[0.022-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.202	NA	0.03087733
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	20q12	20	41168825	PLCG1	PLCG1	NA	NA	ENSG00000124181	NA	NA	rs753381-C	rs753381	0	753381	missense_variant	FALSE	0.5497	8e-9	8.096910013008056	NA	0.02054587	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5497	NA	0.02054587
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	20q13.31	20	57544460	intergenic	CTCFL - PCK1	ENSG00000124092	ENSG00000124253	NA	18808	16620	rs6064559-A	rs6064559	0	6064559	intergenic_variant	TRUE	0.598	7e-10	9.154901959985743	NA	0.02224952	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.598	NA	0.02224952
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	21q21.1	21	15205839	intergenic	NA	NA	NA	NA	NA	NA	rs1997595-C	rs1997595	0	1997595	intron_variant	TRUE	0.3405	1e-16	16	NA	0.03144958	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.3405	NA	0.03144958
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	21q21.1	21	15413369	intergenic	NA - CYCSP42	NA	ENSG00000224524	NA	NA	77161	rs2037978-C	rs2037978	0	2037978	intron_variant	TRUE	0.2814	1e-12	12	NA	0.02862428	[0.021-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2814	NA	0.02862428
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	21q22.11	21	33974555	LINC00649	LINC00649	NA	NA	ENSG00000237945	NA	NA	rs35542019-T	rs35542019	0	35542019	non_coding_transcript_exon_variant	FALSE	0.5749	7e-14	13.154901959985743	NA	0.02693789	[0.02-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5749	NA	0.02693789
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	21q22.13	21	36461960	CLDN14, AP000695.4, AP000695.6	CLDN14	NA	NA	ENSG00000159261	NA	NA	rs128494-C	rs128494	0	128494	intron_variant	FALSE	0.7653	1e-13	13	NA	0.03162489	[0.023-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.7653	NA	0.03162489
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	21q22.13	21	36700056	SIM2, AP000697.6	SIM2	NA	NA	ENSG00000159263	NA	NA	rs2269188-C	rs2269188	0	2269188	intron_variant	FALSE	0.2783	2e-11	10.698970004336019	NA	0.02768442	[0.02-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2783	NA	0.02768442
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	21q22.2	21	39094644	intergenic	NA - RPL23AP12	NA	ENSG00000228861	NA	NA	32924	rs2836882-A	rs2836882	0	2836882	intergenic_variant	TRUE	0.267	2e-9	8.698970004336019	NA	0.02407757	[0.016-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.267	NA	0.02407757
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	22q12.1	22	28807326	CTA-292E10.6	XBP1 - ZNRF3	ENSG00000100219	ENSG00000183579	NA	6729	76246	rs5762813-T	rs5762813	0	5762813	intron_variant	TRUE	0.184	5e-11	10.301029995663981	NA	0.03005343	[0.021-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.184	NA	0.03005343
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	NA	NA	NA	TMPRSS6	NA	NA	NA	NA	NA	NA	chr22:37462936-G	chr22:37462936	0	NA	NA	TRUE	0.5612	6e-169	168.22184874961636	NA	0.09874955	[0.092-0.106] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5612	NA	0.09874955
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	22q12.3	22	37112384	TMPRSS6	TMPRSS6 - IL2RB	ENSG00000187045	ENSG00000100385	NA	2671	13459	rs5756519-C	rs5756519	0	5756519	intergenic_variant	TRUE	0.4272	6e-35	34.221848749616356	NA	0.04432027	[0.037-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.4272	NA	0.04432027
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	22q13.2	22	42719570	A4GALT	A4GALT	NA	NA	ENSG00000128274	NA	NA	rs5758896-C	rs5758896	0	5758896	intron_variant	FALSE	0.5945	7e-18	17.154901959985743	NA	0.03104328	[0.024-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5945	NA	0.03104328
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	22q13.31	22	43928850	PNPLA3	PNPLA3	NA	NA	ENSG00000100344	NA	NA	rs738408-T	rs738408	0	738408	synonymous_variant	FALSE	0.216	3e-12	11.522878745280337	NA	0.03000536	[0.022-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.216	NA	0.03000536
2017-05-11	28098162	Hibar DP	2017-01-18	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28098162	Novel genetic loci associated with hippocampal volume.	Hippocampal volume	26,814 European ancestry individuals	up to 3,863 European ancestry individuals, up to 562 African American individuals, up to 886 Asian ancestry individuals, up to 1,411 Mexican American individuals	12q24.22	12	116885562	HRK	HRK - FBXW8	ENSG00000135116	ENSG00000174989	NA	4121	25388	rs77956314-T	rs77956314	0	77956314	regulatory_region_variant	TRUE	0.916	2e-25	24.69897000433602	(EA)	10.418	[NR] z score decrease	Affymetrix, Illumina, Perlegen [NR] (imputed)	N	hippocampal volume	http://www.ebi.ac.uk/efo/EFO_0005035	GCST003961	Genome-wide genotyping array	0.916	10.418	NA
2017-05-11	28098162	Hibar DP	2017-01-18	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28098162	Novel genetic loci associated with hippocampal volume.	Hippocampal volume	26,814 European ancestry individuals	up to 3,863 European ancestry individuals, up to 562 African American individuals, up to 886 Asian ancestry individuals, up to 1,411 Mexican American individuals	12q14.3	12	65438688	MSRB3	MSRB3	NA	NA	ENSG00000174099	NA	NA	rs61921502-T	rs61921502	0	61921502	intron_variant	FALSE	0.8466	2e-19	18.69897000433602	(EA)	9.017	[NR] z score increase	Affymetrix, Illumina, Perlegen [NR] (imputed)	N	hippocampal volume	http://www.ebi.ac.uk/efo/EFO_0005035	GCST003961	Genome-wide genotyping array	0.8466	9.017	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	16q12.1	16	48619072	N4BP1	N4BP1	NA	NA	ENSG00000102921	NA	NA	rs569868609-C	rs569868609	1	61419189	intron_variant	FALSE	0.3308	5e-11	10.301029995663981	NA	0.02517495	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.3308	NA	0.02517495
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	NA	NA	NA	PLA2G15	NA	NA	NA	NA	NA	NA	chr16:68294800-G	chr16:68294800	0	NA	NA	TRUE	0.7139	6e-10	9.221848749616356	NA	0.02464128	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.7139	NA	0.02464128
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	16q24.1	16	85776743	EMC8	EMC8	NA	NA	ENSG00000131148	NA	NA	rs301161-A	rs301161	0	301161	intron_variant	FALSE	0.8486	7e-11	10.154901959985743	NA	0.03248523	[0.023-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.8486	NA	0.03248523
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	16q24.1	16	85984057	RP11-542M13.2	LINC02132 - NA	ENSG00000268804	NA	NA	47834	NA	rs17445836-A	rs17445836	0	17445836	intron_variant	TRUE	0.2311	3e-10	9.522878745280337	NA	0.02686111	[0.019-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.2311	NA	0.02686111
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	16q24.2	16	88493354	ZFPM1	ZFPM1	NA	NA	ENSG00000179588	NA	NA	rs118090537-A	rs118090537	0	118090537	intron_variant	FALSE	0.2039	7e-14	13.154901959985743	NA	0.03398632	[0.025-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.2039	NA	0.03398632
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17p13.2	17	4618946	RP11-141J13.5, RNU6-955P	LINC01996 - RNU6-955P	ENSG00000261863	ENSG00000222429	NA	1296	803	rs149206763-A	rs149206763	0	149206763	intergenic_variant	TRUE	0.146	1e-15	15	NA	0.04103604	[0.031-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.146	NA	0.04103604
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17q21.33	17	49320708	ZNF652	ZNF652	NA	NA	ENSG00000198740	NA	NA	rs9889262-A	rs9889262	0	9889262	intron_variant	FALSE	0.366	1e-13	13	NA	0.02748114	[0.02-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.366	NA	0.02748114
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17p13.2	17	4632019	ALOX15	ALOX15	NA	NA	ENSG00000161905	NA	NA	rs34210653-A	rs34210653	0	34210653	missense_variant	FALSE	0.0214	2e-42	41.69897000433602	NA	0.168308	[0.14-0.19] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0214	NA	0.168308
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17p13.2	17	4639054	ALOX15	ALOX15	NA	NA	ENSG00000161905	NA	NA	rs113604586-C	rs113604586	0	113604586	missense_variant	FALSE	0.0034	2e-10	9.698970004336019	NA	0.2104417	[0.15-0.28] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0034	NA	0.2104417
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17q24.2	17	67884422	BPTF	BPTF	NA	NA	ENSG00000171634	NA	NA	rs60432162-C	rs60432162	0	60432162	intron_variant	FALSE	0.1978	6e-19	18.221848749616356	NA	0.04065155	[0.032-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.1978	NA	0.04065155
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17q25.1	17	75826517	UNK, UNC13D	UNK - UNC13D	ENSG00000132478	ENSG00000092929	NA	718	708	rs5822105-GC	rs5822105	0	5822105	intergenic_variant	TRUE	0.3435	3e-9	8.522878745280337	NA	0.02234024	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.3435	NA	0.02234024
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17p13.1	17	7839283	KDM6B	KDM6B	NA	NA	ENSG00000132510	NA	NA	rs74480102-A	rs74480102	0	74480102	intron_variant	FALSE	0.043	7e-21	20.154901959985743	NA	0.08243702	[0.065-0.1] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.043	NA	0.08243702
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	1p22.3	1	87286317	intergenic	LINC02801 - LMO4	ENSG00000284240	ENSG00000143013	NA	21576	42563	rs6684992-T	rs6684992	0	6684992	intergenic_variant	TRUE	0.1198	2e-14	13.698970004336019	NA	0.04197895	[0.031-0.053] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.1198	NA	0.04197895
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17q12	17	39799302	IKZF3	IKZF3	NA	NA	ENSG00000161405	NA	NA	rs13313564-A	rs13313564	0	13313564	intron_variant	FALSE	0.0346	2e-9	8.698970004336019	NA	0.05853855	[0.039-0.078] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0346	NA	0.05853855
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17q21.2	17	40608272	intergenic	CCR7 - SMARCE1	ENSG00000126353	ENSG00000073584	NA	42800	16690	rs112401631-A	rs112401631	0	112401631	TF_binding_site_variant	TRUE	0.0231	9e-14	13.045757490560675	NA	0.09615405	[0.071-0.121] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0231	NA	0.09615405
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17q21.31	17	43763481	SOST	SOST - DUSP3	ENSG00000167941	ENSG00000108861	NA	4690	2644	rs77697917-T	rs77697917	0	77697917	intergenic_variant	TRUE	0.0286	2e-10	9.698970004336019	NA	0.06810945	[0.047-0.089] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0286	NA	0.06810945
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	17q21.31	17	46096137	KANSL1	KANSL1, KANSL1, KANSL1	NA	NA	ENSG00000120071, ENSG00000275867, ENSG00000278458	NA	NA	rs776509440-ATTC	rs776509440	0	776509440	intron_variant	FALSE	0.1747	2e-18	17.69897000433602	NA	0.04563918	[0.035-0.056] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.1747	NA	0.04563918
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	18q21.33	18	63253621	BCL2	BCL2	NA	NA	ENSG00000171791	NA	NA	rs17758695-T	rs17758695	0	17758695	intron_variant	FALSE	0.03	7e-25	24.154901959985743	NA	0.1084903	[0.088-0.129] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.03	NA	0.1084903
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	18q21.33	18	63584740	SERPINB13	SERPINB12 - SERPINB13	ENSG00000166634	ENSG00000197641	NA	15411	2249	rs12968338-T	rs12968338	0	12968338	intergenic_variant	TRUE	0.7118	9e-11	10.045757490560675	NA	0.02573811	[0.018-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.7118	NA	0.02573811
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	19q13.2	19	38409359	RASGRP4	RASGRP4	NA	NA	ENSG00000171777	NA	NA	rs4802399-A	rs4802399	0	4802399	3_prime_UTR_variant	FALSE	0.0437	2e-9	8.698970004336019	NA	0.05269587	[0.036-0.07] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0437	NA	0.05269587
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	19q13.2	19	39735635	CLC	CLC	NA	NA	ENSG00000105205	NA	NA	rs395892-G	rs395892	0	395892	intron_variant	FALSE	0.6705	6e-58	57.221848749616356	NA	0.06079871	[0.053-0.068] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.6705	NA	0.06079871
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	19p13.3	19	1079960	HMHA1	ARHGAP45	NA	NA	ENSG00000180448	NA	NA	rs36084354-A	rs36084354	0	36084354	missense_variant	FALSE	0.092	4e-12	11.397940008672037	NA	0.04275776	[0.031-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.092	NA	0.04275776
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	19q13.32	19	45239644	MARK4, AC006126.4	EXOC3L2, MARK4	NA	NA	ENSG00000283632, ENSG00000007047	NA	NA	rs145605569-T	rs145605569	0	145605569	intron_variant	FALSE	0.259	1e-15	15	NA	0.03286374	[0.025-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.259	NA	0.03286374
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	19q13.32	19	45721713	FBXO46	FBXO46	NA	NA	ENSG00000177051	NA	NA	rs36120341-T	rs36120341	0	36120341	intron_variant	FALSE	0.362	6e-12	11.221848749616356	NA	0.02565502	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.362	NA	0.02565502
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil counts	172,275 European ancestry individuals	NA	19q13.32	19	45856536	SYMPK	SYMPK	NA	NA	ENSG00000125755	NA	NA	rs76793172-T	rs76793172	0	76793172	intron_variant	FALSE	0.0921	2e-17	16.69897000433602	NA	0.05245408	[0.04-0.065] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004842	GCST004606	Genome-wide genotyping array	0.0921	NA	0.05245408
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	2p25.1	2	8600592	ID2	LINC01814 - SNRPEP5	ENSG00000236008	ENSG00000225642	NA	7689	2490	rs10929547-A	rs10929547	0	10929547	intergenic_variant	TRUE	NR	1e-11	11	NA	0.002	[0.0014-0.0026] unit decrease	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	0.002
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	6p22.1	6	27893892	NR	H2BC17 - RNU7-26P	ENSG00000274641	ENSG00000238610	NA	1	3612	rs13219787-?	rs13219787	0	13219787	regulatory_region_variant	TRUE	NR	1e-9	9	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	6p21.1	6	41957421	CCND3	CCND3	NA	NA	ENSG00000112576	NA	NA	rs9349205-?	rs9349205	0	9349205	intron_variant	FALSE	NR	9e-62	61.045757490560675	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	6q21	6	109295217	CD164	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs9374080-?	rs9374080	0	9374080	intron_variant	FALSE	NR	6e-17	16.221848749616356	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	3q29	3	196192085	ZDHHC19	LINC00885 - ZDHHC19	ENSG00000224652	ENSG00000163958	NA	31192	5367	rs3893275-A	rs3893275	0	3893275	regulatory_region_variant	TRUE	NR	7e-8	7.154901959985743	(Asian)	0.0033	[0.0021-0.0045] unit increase	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	0.0033
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	5p15.33	5	1286401	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs2736100-A	rs2736100	0	2736100	3_prime_UTR_variant	FALSE	NR	3e-6	5.522878745280337	(Asian)	0.0028	[0.0016-0.004] unit increase	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	0.0028
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	6q21	6	109295217	CD164	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs9374080-T	rs9374080	0	9374080	intron_variant	FALSE	NR	3e-6	5.522878745280337	(Asian)	0.0045	[0.0025-0.0065] unit decrease	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	0.0045
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	7p12.2	7	50360747	IKZF1	IKZF1	NA	NA	ENSG00000185811	NA	NA	rs12718598-?	rs12718598	0	12718598	intron_variant	FALSE	NR	4e-14	13.397940008672037	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	NA	NA	NA	ABO	NA	NA	NA	NA	NA	NA	rs8176749-T	rs8176749	0	8176749	synonymous_variant	TRUE	NR	5e-7	6.301029995663981	(Asian)	0.0039	[0.0023-0.0055] unit decrease	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	0.0039
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	9p24.1	9	4856877	RCL1	RCL1	NA	NA	ENSG00000120158	NA	NA	rs10758658-?	rs10758658	0	10758658	intron_variant	FALSE	NR	5e-23	22.30102999566398	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	12q24.13	12	112207597	NR	HECTD4	NA	NA	ENSG00000173064	NA	NA	rs2074356-A	rs2074356	0	2074356	intron_variant	FALSE	NR	2e-10	9.698970004336019	(Asian)	0.004	[0.0028-0.0052] unit decrease	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	0.004
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	11p15.4	11	5209677	NR	OR51V1 - HBB	ENSG00000176742	ENSG00000244734	NA	8995	15787	rs7120391-?	rs7120391	0	7120391	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	22q13.33	22	50532837	LOC440836	ODF3B - KLHDC7B-DT	ENSG00000177989	ENSG00000272666	NA	331	9468	rs140522-T	rs140522	0	140522	regulatory_region_variant	TRUE	NR	1e-6	6	(Asian)	0.0032	[0.0018-0.0046] unit decrease	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	0.0032
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	22q12.3	22	37074184	TMPRSS6	TMPRSS6	NA	NA	ENSG00000187045	NA	NA	rs2413450-T	rs2413450	0	2413450	intron_variant	FALSE	NR	4e-11	10.397940008672037	(Asian)	0.0039	[0.0027-0.0051] unit decrease	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	0.0039
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	17q11.2	17	28875870	NR	MIR4732 - FLOT2	ENSG00000284085	ENSG00000132589	NA	14140	3465	rs7221773-?	rs7221773	0	7221773	regulatory_region_variant	TRUE	NR	7e-8	7.154901959985743	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	18q21.1	18	46253312	NR	C18orf25	NA	NA	ENSG00000152242	NA	NA	rs4890633-?	rs4890633	0	4890633	intron_variant	FALSE	NR	5e-9	8.301029995663981	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	19p13.3	19	4366222	NR	SH3GL1	NA	NA	ENSG00000141985	NA	NA	rs732716-?	rs732716	0	732716	intron_variant	FALSE	NR	3e-9	8.522878745280337	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	19p13.13	19	12821455	NR	HOOK2	NA	NA	ENSG00000095066	NA	NA	rs7255045-?	rs7255045	0	7255045	intron_variant	FALSE	NR	5e-33	32.30102999566398	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	9q31.1	9	104929542	ABCA1	ABCA1 - CT70	ENSG00000165029	ENSG00000230013	NA	1387	41051	rs2487048-A	rs2487048	0	2487048	intergenic_variant	TRUE	NR	5e-9	8.301029995663981	(EA)	0.16	[0.1-0.22] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.16
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	9q31.1	9	104929542	ABCA1	ABCA1 - CT70	ENSG00000165029	ENSG00000230013	NA	1387	41051	rs2487048-A	rs2487048	0	2487048	intergenic_variant	TRUE	NR	5e-13	12.301029995663981	NA	0.15	[0.11-0.19] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.15
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	9q34.2	9	133256074	ABO	ABO, ABO	NA	NA	ENSG00000175164, ENSG00000281879	NA	NA	rs8176741-A	rs8176741	0	8176741	synonymous_variant	FALSE	NR	3e-7	6.522878745280337	(EA)	0.26	[0.16-0.36] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.26
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	9q34.2	9	133256074	ABO	ABO, ABO	NA	NA	ENSG00000175164, ENSG00000281879	NA	NA	rs8176741-A	rs8176741	0	8176741	synonymous_variant	FALSE	NR	3e-10	9.522878745280337	NA	0.24	[0.16-0.32] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.24
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	11q24.3	11	130414146	ADAMTS8	ADAMTS8	NA	NA	ENSG00000134917	NA	NA	rs55796939-T	rs55796939	0	55796939	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(EA)	0.38	[0.22-0.54] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.38
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	11q24.3	11	130414146	ADAMTS8	ADAMTS8	NA	NA	ENSG00000134917	NA	NA	rs55796939-T	rs55796939	0	55796939	intron_variant	FALSE	NR	2e-8	7.698970004336019	NA	0.36	[0.24-0.48] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.36
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	7q31.2	7	116511284	CAV1, CAV2	CAV2 - CAV1	ENSG00000105971	ENSG00000105974	NA	2743	13710	rs10281637-C	rs10281637	0	10281637	intergenic_variant	TRUE	NR	1e-11	11	(EA)	0.2	[0.14-0.26] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.2
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	7q31.2	7	116511284	CAV1, CAV2	CAV2 - CAV1	ENSG00000105971	ENSG00000105974	NA	2743	13710	rs10281637-C	rs10281637	0	10281637	intergenic_variant	TRUE	NR	4e-13	12.397940008672037	NA	0.2	[0.14-0.26] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.2
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	3q26.31	3	172271486	FNDC3B	FNDC3B	NA	NA	ENSG00000075420	NA	NA	rs7635832-G	rs7635832	0	7635832	intron_variant	FALSE	NR	3e-12	11.522878745280337	(EA)	0.25	[0.17-0.33] unit decrease	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.25
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	3q26.31	3	172271486	FNDC3B	FNDC3B	NA	NA	ENSG00000075420	NA	NA	rs7635832-G	rs7635832	0	7635832	intron_variant	FALSE	NR	7e-13	12.154901959985743	NA	0.22	[0.16-0.28] unit decrease	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.22
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	17p13.1	17	10127866	GAS7	GAS7	NA	NA	ENSG00000007237	NA	NA	rs9913911-G	rs9913911	0	9913911	intron_variant	FALSE	NR	1e-12	12	(EA)	0.2	[0.14-0.26] unit decrease	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.2
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	17p13.1	17	10127866	GAS7	GAS7	NA	NA	ENSG00000007237	NA	NA	rs9913911-G	rs9913911	0	9913911	intron_variant	FALSE	NR	7e-12	11.154901959985743	NA	0.17	[0.13-0.21] unit decrease	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.17
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	11p11.2	11	47934056	genic	NUP160 - PTPRJ	ENSG00000030066	ENSG00000149177	NA	85501	46502	rs7944735-C	rs7944735	0	7944735	regulatory_region_variant	TRUE	NR	1e-9	9	(EA)	0.2	[0.14-0.26] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.2
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	11p11.2	11	47934056	genic	NUP160 - PTPRJ	ENSG00000030066	ENSG00000149177	NA	85501	46502	rs7944735-C	rs7944735	0	7944735	regulatory_region_variant	TRUE	NR	6e-11	10.221848749616356	NA	0.19	[0.13-0.25] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.19
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	1q24.1	1	165745179	TMCO1	TMCO1	NA	NA	ENSG00000143183	NA	NA	rs10918274-T	rs10918274	0	10918274	intron_variant	FALSE	NR	2e-12	11.698970004336019	(EA)	0.27	[0.19-0.35] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.27
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	1q24.1	1	165745179	TMCO1	TMCO1	NA	NA	ENSG00000143183	NA	NA	rs10918274-T	rs10918274	0	10918274	intron_variant	FALSE	NR	6e-12	11.221848749616356	NA	0.25	[0.17-0.33] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.25
2017-05-24	28073927	Springelkamp H	2017-01-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28073927	New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.	Intraocular pressure	25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals	8,352 Asian ancestry individuals	11q23.3	11	120418990	ARHGEF12	ARHGEF12	NA	NA	ENSG00000196914	NA	NA	rs12794618-C	rs12794618	0	12794618	intron_variant	FALSE	NR	2e-9	8.698970004336019	NA	0.18	[0.12-0.24] unit increase	Affymetrix, Illumina [~ 8000000] (imputed)	N	intraocular pressure measurement	http://www.ebi.ac.uk/efo/EFO_0004695	GCST004074	Genome-wide genotyping array	NA	NA	0.18
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	12q21.32	12	86467199	MGAT4C	MGAT4C	NA	NA	ENSG00000182050	NA	NA	rs140444490-C	rs140444490	0	140444490	intron_variant	FALSE	0.999	1e-6	6	(AA)	0.431	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	5q15	5	94360594	KIAA0825	KIAA0825	NA	NA	ENSG00000185261	NA	NA	rs138833221-A	rs138833221	0	138833221	intron_variant	FALSE	0.998	1e-6	6	(AA)	0.217	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.998	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	1q31.3	1	195774530	Intergenic	NA	NA	NA	NA	NA	NA	rs74507156-A	rs74507156	0	74507156	intergenic_variant	TRUE	1.0	1e-6	6	(AA)	0.454	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	20q13.32	20	58695608	NPEPL1	NPEPL1, STX16-NPEPL1	NA	NA	ENSG00000215440, ENSG00000254995	NA	NA	rs117094540-T	rs117094540	0	117094540	intron_variant	FALSE	0.999	1e-6	6	(AA)	0.35	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3p14.1	3	65521486	MAGI1	MAGI1, MAGI1	NA	NA	ENSG00000151276, ENSG00000282956	NA	NA	rs188500549-A	rs188500549	0	188500549	intron_variant	FALSE	1.0	1e-6	6	(AA)	0.573	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11p12	11	40624331	LRRC4C	LRRC4C	NA	NA	ENSG00000148948	NA	NA	rs184852128-T	rs184852128	0	184852128	intron_variant	FALSE	1.0	1e-6	6	(AA)	0.432	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	6q24.1	6	139456693	Intergenic	LINC01625	NA	NA	ENSG00000238099	NA	NA	rs184091137-T	rs184091137	0	184091137	intron_variant	FALSE	1.0	1e-6	6	(AA)	0.705	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	16q23.1	16	78903855	WWOX	WWOX	NA	NA	ENSG00000186153	NA	NA	rs62038064-G	rs62038064	0	62038064	intron_variant	FALSE	0.956	1e-6	6	(AA)	0.042	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.956	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	12q23.1	12	100959756	ANO4	ANO4	NA	NA	ENSG00000151572	NA	NA	rs188024766-G	rs188024766	0	188024766	intron_variant	FALSE	1.0	1e-6	6	(AA)	0.377	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	12q14.3	12	66788009	GRIP1	GRIP1	NA	NA	ENSG00000155974	NA	NA	rs147616082-A	rs147616082	0	147616082	intron_variant	FALSE	1.0	1e-6	6	(AA)	0.764	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	12q23.3	12	107234902	Intergenic	NA - SETP7	NA	ENSG00000257444	NA	NA	36492	rs189340018-C	rs189340018	0	189340018	intergenic_variant	TRUE	1.0	1e-6	6	(AA)	0.804	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	2p16.1	2	55970665	BC043355	MIR217HG	NA	NA	ENSG00000226702	NA	NA	rs138402956-C	rs138402956	0	138402956	intron_variant	FALSE	0.996	1e-6	6	(AA)	0.168	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.996	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	7q36.1	7	152019626	GALNTL5	GALNTL5	NA	NA	ENSG00000106648	NA	NA	rs141892389-A	rs141892389	0	141892389	intron_variant	FALSE	0.999	1e-6	6	(AA)	0.495	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q13.3	11	70464940	Intergenic	CTTN - SHANK2	ENSG00000085733	ENSG00000162105	NA	28356	2914	rs180910263-G	rs180910263	0	180910263	regulatory_region_variant	TRUE	1.0	1e-6	6	(AA)	0.625	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q21.1	15	47756369	SEMA6D	SEMA6D	NA	NA	ENSG00000137872	NA	NA	rs192229215-A	rs192229215	0	192229215	intron_variant	FALSE	1.0	1e-6	6	(AA)	0.634	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	22q11.22	22	22004543	AK131325	PRAMENP	NA	NA	ENSG00000197549	NA	NA	rs182382461-G	rs182382461	0	182382461	intron_variant	FALSE	0.999	1e-6	6	(AA)	0.509	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	12q23.3	12	107274025	Intergenic	SETP7 - BTBD11	ENSG00000257444	ENSG00000151136	NA	2179	44396	rs182328274-T	rs182328274	0	182328274	intergenic_variant	TRUE	1.0	1e-6	6	(AA)	0.801	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q21.3	15	57793174	Intergenic	POLR2M - NA	ENSG00000255529	NA	NA	10412	NA	rs114831632-A	rs114831632	0	114831632	regulatory_region_variant	TRUE	0.995	1e-6	6	(AA)	0.122	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.995	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	12q23.3	12	107254627	Intergenic	NA - SETP7	NA	ENSG00000257444	NA	NA	16767	rs192256367-T	rs192256367	0	192256367	intergenic_variant	TRUE	1.0	1e-6	6	(AA)	0.801	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	16p13.2	16	8072670	Intergenic	NA	NA	NA	NA	NA	NA	rs184252378-G	rs184252378	0	184252378	intron_variant	TRUE	1.0	1e-6	6	(AA)	1.006	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	8p21.2	8	25271207	DOCK5	DOCK5	NA	NA	ENSG00000147459	NA	NA	rs182115318-T	rs182115318	0	182115318	3_prime_UTR_variant	FALSE	0.995	1e-6	6	(AA)	0.149	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.995	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q25.33	3	160837076	PPM1L	PPM1L	NA	NA	ENSG00000163590	NA	NA	rs149794616-C	rs149794616	0	149794616	intron_variant	FALSE	0.999	1e-6	6	(AA)	0.45	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3p24.1	3	29039771	Intergenic	RBMS3	NA	NA	ENSG00000144642	NA	NA	rs187206368-A	rs187206368	0	187206368	intron_variant	FALSE	0.997	1e-6	6	(AA)	0.199	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.997	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q12	4	54078576	PDGFRA	CHIC2 - MORF4L2P1	ENSG00000109220	ENSG00000250147	NA	13971	8350	rs192046469-T	rs192046469	0	192046469	intron_variant	TRUE	0.999	1e-6	6	(AA)	0.336	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q21.3	15	57797137	Intergenic	POLR2M - NA	ENSG00000255529	NA	NA	14375	NA	rs140526800-T	rs140526800	0	140526800	regulatory_region_variant	TRUE	0.995	1e-6	6	(AA)	0.121	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.995	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	21q22.3	21	43301147	CRYAA, SIK1	NA - LINC00322	NA	ENSG00000237864	NA	NA	21270	rs112204826-C	rs112204826	0	112204826	intergenic_variant	TRUE	NA	3e-8	7.522878745280337	NA	0.395	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q24.3	11	130403335	ZBTB44, ADAMTS8	ZBTB44-DT	NA	NA	ENSG00000175773	NA	NA	rs11222084-A	rs11222084	0	11222084	non_coding_transcript_exon_variant	FALSE	NA	1e-12	12	NA	0.175	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q24.13	8	125494452	TRIB1, LOC100130231	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	56049	365269	rs112875651-G	rs112875651	0	112875651	intron_variant	TRUE	NA	8e-6	5.096910013008056	NA	0.11	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q15.1	15	41042016	INO80	INO80	NA	NA	ENSG00000128908	NA	NA	rs112925537-A	rs112925537	0	112925537	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.204	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q25.2	3	154898030	GPR149, MME	NA	NA	NA	NA	NA	NA	rs113161639-G	rs113161639	0	113161639	intergenic_variant	TRUE	NA	3e-13	12.522878745280337	NA	0.288	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q33.2	2	203289954	CYP20A1	CYP20A1	NA	NA	ENSG00000119004	NA	NA	rs114407963-A	rs114407963	0	114407963	intron_variant	FALSE	NA	7e-6	5.154901959985743	NA	0.162	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p22.1	3	41841413	NR	ULK4	NA	NA	ENSG00000168038	NA	NA	rs114714860-G	rs114714860	0	114714860	intron_variant	FALSE	NA	2e-30	29.69897000433602	NA	0.352	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7p22.3	7	2452283	CHST12, MIR4648	CHST12 - GRIFIN	ENSG00000136213	ENSG00000275572	NA	3799	22561	rs11486794-C	rs11486794	0	11486794	regulatory_region_variant	TRUE	NA	8e-10	9.096910013008056	NA	0.219	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q15	12	69931889	RAB3IP, CNOT2	PRANCR, MYRFL	NA	NA	ENSG00000257815, ENSG00000166268	NA	NA	rs1152958-G	rs1152958	0	1152958	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.138	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q32.2	7	130023656	ZC3HC1	ZC3HC1	NA	NA	ENSG00000091732	NA	NA	rs11556924-C	rs11556924	0	11556924	missense_variant	FALSE	NA	8e-13	12.096910013008056	NA	0.181	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q23	15	71314041	THSD4	THSD4	NA	NA	ENSG00000187720	NA	NA	rs11631778-G	rs11631778	0	11631778	intron_variant	FALSE	NA	1e-8	8	NA	0.141	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5p13.3	5	32814922	NPR3, LOC340113	NPR3 - NA	ENSG00000113389	NA	NA	23198	NA	rs1173771-A	rs1173771	0	1173771	regulatory_region_variant	TRUE	NA	8e-16	15.096910013008056	NA	0.19	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q23	15	69383266	PAQR5	PAQR5	NA	NA	ENSG00000137819	NA	NA	rs117638970-C	rs117638970	0	117638970	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.484	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	21q22.2	21	38611524	ERG	ERG	NA	NA	ENSG00000157554	NA	NA	rs117870289-C	rs117870289	0	117870289	intron_variant	FALSE	NA	1e-6	6	NA	0.537	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q33.3	5	158418394	CLINT1, EBF1	LINC02227 - NA	ENSG00000276778	NA	NA	8621	NA	rs11953630-C	rs11953630	0	11953630	intergenic_variant	TRUE	NA	3e-19	18.522878745280337	NA	0.218	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7p12.3	7	45968511	IGFBP3, TNS3	IGFBP3 - FTLP15	ENSG00000146674	ENSG00000233952	NA	46637	29029	rs11977526-G	rs11977526	0	11977526	intron_variant	TRUE	NA	4e-12	11.397940008672037	NA	0.166	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q11.21	8	51024072	SNTG1, PXDNL	NA	NA	NA	NA	NA	NA	rs11993898-T	rs11993898	0	11993898	intergenic_variant	TRUE	NA	1e-7	7	NA	0.159	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p36.22	1	10739520	NR	CASZ1	NA	NA	ENSG00000130940	NA	NA	rs12046278-T	rs12046278	0	12046278	intron_variant	FALSE	NA	2e-12	11.698970004336019	NA	0.181	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1q24.3	1	172388301	DNM3	PIGC, DNM3	NA	NA	ENSG00000135845, ENSG00000197959	NA	NA	rs12405515-G	rs12405515	0	12405515	intron_variant	FALSE	NA	1e-12	12	NA	0.17	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4p11	4	48932281	OCIAD2, CWH43	OCIAD2 - RNU6-158P	ENSG00000145247	ENSG00000252913	NA	25344	474	rs12504699-G	rs12504699	0	12504699	intergenic_variant	TRUE	NA	6e-6	5.221848749616356	NA	0.109	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q21.21	4	80261400	NR	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675	NA	57071	5239	rs12509595-T	rs12509595	0	12509595	intergenic_variant	TRUE	NA	2e-61	60.69897000433602	NA	0.427	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12p12.2	12	20020830	LOC100506393	LINC02398	NA	NA	ENSG00000256287	NA	NA	rs12579720-C	rs12579720	0	12579720	intron_variant	FALSE	NA	2e-19	18.69897000433602	NA	0.24	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16p13.3	16	4896793	PPL	PPL	NA	NA	ENSG00000118898	NA	NA	rs12596053-A	rs12596053	0	12596053	intron_variant	FALSE	NA	1e-11	11	NA	0.162	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p25.1	3	14912904	FGD5	FGD5	NA	NA	ENSG00000154783	NA	NA	rs12630213-C	rs12630213	0	12630213	intron_variant	FALSE	NA	5e-10	9.301029995663981	NA	0.153	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7p22.3	7	1692230	TFAMP1, ELFN1	ELFN1	NA	NA	ENSG00000225968	NA	NA	rs12670854-A	rs12670854	0	12670854	intron_variant	FALSE	NA	9e-6	5.045757490560675	NA	0.171	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	NA	NA	NA	RERE	NA	NA	NA	NA	NA	NA	chr1:8472788-?	chr1:8472788	0	NA	NA	TRUE	NA	2e-9	8.698970004336019	NA	7.916	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr20:57738070-?	chr20:57738070	0	NA	NA	TRUE	NA	5e-8	7.301029995663981	NA	0.291	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	NA	NA	NA	NR	NA	NA	NA	NA	NA	NA	chr5:122699198-?	chr5:122699198	0	NA	NA	TRUE	NA	4e-11	10.397940008672037	NA	0.232	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q24.32	10	102834750	CYP17A1	CYP17A1	NA	NA	ENSG00000148795	NA	NA	rs1004467-A	rs1004467	0	1004467	non_coding_transcript_exon_variant	FALSE	NA	6e-17	16.221848749616356	NA	0.319	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q21.13	8	81937217	SNX16, RALYL	LINC02235 - NA	ENSG00000254689	NA	NA	12869	NA	rs10103353-C	rs10103353	0	10103353	regulatory_region_variant	TRUE	NA	4e-10	9.397940008672037	NA	0.147	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q22.1	7	100028412	ZKSCAN1	ZKSCAN1	NA	NA	ENSG00000106261	NA	NA	rs1015538-A	rs1015538	0	1015538	intron_variant	FALSE	NA	3e-8	7.522878745280337	NA	0.137	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p23.3	2	24907673	ADCY3	ADCY3	NA	NA	ENSG00000138031	NA	NA	rs10198275-A	rs10198275	0	10198275	intron_variant	FALSE	NA	6e-9	8.221848749616356	NA	0.135	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q36.1	7	151717955	PRKAG2	PRKAG2	NA	NA	ENSG00000106617	NA	NA	rs10224002-A	rs10224002	0	10224002	intron_variant	FALSE	NA	2e-11	10.698970004336019	NA	0.174	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7p12.3	7	45970501	IGFBP3, TNS3	IGFBP3 - FTLP15	ENSG00000146674	ENSG00000233952	NA	48627	27039	rs10260816-C	rs10260816	0	10260816	intron_variant	TRUE	NA	6e-14	13.221848749616356	NA	0.178	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	19p13.2	19	7259335	INSR	INSR	NA	NA	ENSG00000171105	NA	NA	rs10427021-T	rs10427021	0	10427021	intron_variant	FALSE	NA	5e-22	21.30102999566398	NA	0.343	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p14.3	3	57757519	SLMAP	SLMAP	NA	NA	ENSG00000163681	NA	NA	rs1053711-G	rs1053711	0	1053711	5_prime_UTR_variant	FALSE	NA	2e-9	8.698970004336019	NA	0.153	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q35	2	217804009	TNS1	TNS1	NA	NA	ENSG00000079308	NA	NA	rs1063281-C	rs1063281	0	1063281	3_prime_UTR_variant	FALSE	NA	1e-12	12	NA	0.17	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q13.12	12	50116154	COX14	COX14	NA	NA	ENSG00000178449	NA	NA	rs10747570-A	rs10747570	0	10747570	intron_variant	FALSE	NA	4e-14	13.397940008672037	NA	0.184	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10p15.1	10	4130519	KLF6, LOC338588	NA - LINC00702	NA	ENSG00000233117	NA	NA	70622	rs10751962-C	rs10751962	0	10751962	intergenic_variant	TRUE	NA	5e-8	7.301029995663981	NA	0.219	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q24.3	11	130396222	NR	ZBTB44-DT	NA	NA	ENSG00000175773	NA	NA	rs10894192-T	rs10894192	0	10894192	intron_variant	FALSE	NA	2e-11	10.698970004336019	NA	0.163	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10p12.31	10	18419869	CACNB2	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs11014166-A	rs11014166	0	11014166	intron_variant	FALSE	NA	1e-22	22	NA	0.242	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10p12.31	10	18448045	NR	CACNB2	NA	NA	ENSG00000165995	NA	NA	rs11014267-G	rs11014267	0	11014267	intron_variant	FALSE	NA	8e-25	24.096910013008056	NA	0.259	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q21	11	95575690	SESN3, FAM76B	SESN3 - FAM76B	ENSG00000149212	ENSG00000077458	NA	343149	193263	rs11021221-T	rs11021221	0	11021221	intron_variant	TRUE	NA	3e-11	10.522878745280337	NA	0.213	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p14.1	11	27706555	BDNF	BDNF	NA	NA	ENSG00000176697	NA	NA	rs11030119-G	rs11030119	0	11030119	intron_variant	FALSE	NA	2e-12	11.698970004336019	NA	0.18	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q24.21	12	115760536	TBX3, MIR620	RN7SL865P - LINC02463	ENSG00000240205	ENSG00000257683	NA	42523	49823	rs11067763-A	rs11067763	0	11067763	intron_variant	TRUE	NA	3e-9	8.522878745280337	NA	0.217	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p13.2	1	115294125	NGF	NGF, NGF-AS1	NA	NA	ENSG00000134259, ENSG00000228035	NA	NA	rs11102916-C	rs11102916	0	11102916	intron_variant	FALSE	NA	1e-11	11	NA	0.575	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q21.33	12	89632685	NR	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs11105352-G	rs11105352	0	11105352	intron_variant	FALSE	NA	3e-24	23.522878745280337	NA	0.321	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q11.2	5	57293715	GPBP1, ACTBL2	GPBP1 - NA	ENSG00000062194	NA	NA	29036	NA	rs111304266-C	rs111304266	0	111304266	intergenic_variant	TRUE	NA	3e-8	7.522878745280337	NA	0.37	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q36.3	7	158255704	PTPRN2	PTPRN2, PTPRN2	NA	NA	ENSG00000282185, ENSG00000155093	NA	NA	rs111630016-C	rs111630016	0	111630016	intron_variant	FALSE	NA	3e-8	7.522878745280337	NA	0.324	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q13.11	12	47809158	HDAC7	HDAC7	NA	NA	ENSG00000061273	NA	NA	rs11168244-C	rs11168244	0	11168244	intron_variant	FALSE	NA	5e-8	7.301029995663981	NA	0.165	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury	862 European ancestry cases and 10,588 European ancestry controls	NA	2p25.2	2	5092045	NR	NA	NA	NA	NA	NA	NA	rs72631567-?	rs72631567	0	72631567	intergenic_variant	TRUE	0.03	1e-8	8	NA	2	1.6-2.5	Illumina [505740] (imputed)	N	drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0004228	GCST004086	Genome-wide genotyping array	0.03	2	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury	862 European ancestry cases and 10,588 European ancestry controls	NA	6p22.1	6	29959505	MHC	HLA-W - MICD	ENSG00000235144	ENSG00000237395	NA	935	11296	rs114577328-?	rs114577328	0	114577328	intron_variant	TRUE	0.01	2e-8	7.698970004336019	NA	2.7	1.9-3.8	Illumina [505740] (imputed)	N	drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0004228	GCST004086	Genome-wide genotyping array	0.01	2.7	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury	862 European ancestry cases and 10,588 European ancestry controls	NA	NA	NA	NA	MHC	NA	NA	NA	NA	NA	NA	A3*33:01-?	A3*33:01	0	NA	NA	TRUE	0.01	8e-8	7.096910013008056	NA	2.6	1.8-3.7	Illumina [505740] (imputed)	N	drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0004228	GCST004086	Genome-wide genotyping array	0.01	2.6	NA
2017-05-24	28043905	Nicoletti P	2016-12-30	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/28043905	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.	Drug-induced liver injury	862 European ancestry cases and 10,588 European ancestry controls	NA	NA	NA	NA	MHC	NA	NA	NA	NA	NA	NA	A*33:01-B*14:02-C*08:02-?	A*33:01-B*14:02-C*08:02	0	NA	NA	TRUE	0.009	2e-7	6.698970004336019	NA	2.7	NA	Illumina [505740] (imputed)	N	drug-induced liver injury	http://www.ebi.ac.uk/efo/EFO_0004228	GCST004086	Genome-wide genotyping array	0.009	2.7	NA
2017-05-11	28017375	van Rooij FJA	2016-12-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Mean corpuscular volume	up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals.	16,389 individuals of European and African American ancestry.	14q23.3	14	65035521	FNTB	FNTB, MAX, CHURC1-FNTB	NA	NA	ENSG00000257365, ENSG00000125952, ENSG00000125954	NA	NA	rs7155454-?	rs7155454	0	7155454	intron_variant	FALSE	NR	1e-8	8	NA	NA	NA	NR [2500000] (imputed)	N	mean corpuscular volume	http://www.ebi.ac.uk/efo/EFO_0004526	GCST004004	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	6p21.32	6	32658626	HLA-DQB1, HLA-DQA1	HLA-DQA1 - HLA-DQB1	ENSG00000196735	ENSG00000206237	NA	11564	841	rs34004019-?	rs34004019	0	34004019	regulatory_region_variant	TRUE	NR	3e-24	23.522878745280337	NA	1.1086475	[1.09-1.13]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.1086475	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	5q22.1	5	111131801	WDR36, CAMK4	WDR36 - RPS3AP21	ENSG00000134987	ENSG00000214784	NA	1299	60425	rs1438673-?	rs1438673	0	1438673	regulatory_region_variant	TRUE	NR	3e-17	16.522878745280337	NA	1.0672358	[1.05-1.08]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.0672358	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	16p13.13	16	11183501	CLEC16A, SOCS1	CLEC16A - HNRNPCP4	ENSG00000038532	ENSG00000263179	NA	1315	59152	rs11644510-?	rs11644510	0	11644510	regulatory_region_variant	TRUE	NR	2e-16	15.698970004336019	NA	1.0706638	[1.05-1.09]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.0706638	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	4p14	4	38809430	TLR1, TLR6	TLR1	NA	NA	ENSG00000174125	NA	NA	rs11727978-?	rs11727978	0	11727978	intron_variant	FALSE	NR	1e-15	15	NA	1.083	[1.062-1.104]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.083	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	17q21.1	17	39910767	GSDMB	GSDMB	NA	NA	ENSG00000073605	NA	NA	rs4795400-?	rs4795400	0	4795400	intron_variant	FALSE	NR	3e-15	14.522878745280337	NA	1.0626993	[1.05-1.08]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.0626993	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	11q13.5	11	76582714	C11orf30, LRRC32	EMSY - LINC02757	ENSG00000158636	ENSG00000255363	NA	29689	25139	rs7936323-?	rs7936323	0	7936323	intergenic_variant	TRUE	NR	1e-14	14	NA	1.0604454	[1.04-1.08]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.0604454	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	2q37.3	2	241753075	D2HGDH	D2HGDH	NA	NA	ENSG00000180902	NA	NA	rs35061832-?	rs35061832	0	35061832	intron_variant	FALSE	NR	3e-13	12.522878745280337	NA	1.1	[1.073-1.129]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.1	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	1p36.23	1	8641229	RERE	RERE	NA	NA	ENSG00000142599	NA	NA	rs4908769-?	rs4908769	0	4908769	intron_variant	FALSE	NR	2e-12	11.698970004336019	NA	1.061	[1.044-1.079]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.061	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	12q24.31	12	123286485	CDK2AP1, SBNO1	RNA5SP375 - SBNO1	ENSG00000199845	ENSG00000139697	NA	3451	2624	rs9739070-?	rs9739070	0	9739070	intergenic_variant	TRUE	NR	1e-11	11	NA	1.067	[1.047-1.087]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.067	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	2p25.1	2	8309993	ID2	LINC00299	NA	NA	ENSG00000236790	NA	NA	rs367023-?	rs367023	0	367023	intron_variant	FALSE	NR	2e-11	10.698970004336019	NA	1.0582011	[1.04-1.08]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.0582011	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	4q27	4	122496409	IL2, IL21	IL2 - NA	ENSG00000109471	NA	NA	39684	NA	rs148505069-?	rs148505069	0	148505069	intergenic_variant	TRUE	NR	4e-11	10.397940008672037	NA	1.056	[1.039-1.073]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.056	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	10p14	10	9010779	GATA3	LINC02676 - LINC00709	ENSG00000234752	ENSG00000230014	NA	96183	265054	rs1775550-?	rs1775550	0	1775550	intergenic_variant	TRUE	NR	6e-11	10.221848749616356	NA	1.067	[1.047-1.088]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.067	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	9p24.1	9	6213829	RANBP6, IL33	GTF3AP1 - IL33	ENSG00000237274	ENSG00000137033	NA	16581	1957	rs10975488-?	rs10975488	0	10975488	intergenic_variant	TRUE	NR	8e-11	10.096910013008056	NA	1.087	[1.060-1.115]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.087	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	11q23.3	11	118805063	DDX6, CXCR5	DDX6 - SETP16	ENSG00000110367	ENSG00000254621	NA	13899	28783	rs11217036-?	rs11217036	0	11217036	intergenic_variant	TRUE	NR	9e-11	10.045757490560675	NA	1.0649627	[1.04-1.09]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.0649627	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	10q24.32	10	102518505	SUFU	SUFU	NA	NA	ENSG00000107882	NA	NA	rs201333164-?	rs201333164	0	201333164	intron_variant	FALSE	NR	1e-10	10	NA	1.062	[1.042-1.081]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.062	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	2q33.1	2	198079128	PLCL1	PLCL1	NA	NA	ENSG00000115896	NA	NA	rs2164068-?	rs2164068	0	2164068	intron_variant	FALSE	NR	2e-10	9.698970004336019	NA	1.051	[1.035-1.067]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.051	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	14q21.1	14	37682050	FOXA1, TTC6	TTC6	NA	NA	ENSG00000139865	NA	NA	rs61977073-?	rs61977073	0	61977073	intron_variant	FALSE	NR	4e-10	9.397940008672037	NA	1.061	[1.041-1.080]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.061	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	5q31.1	5	132660151	IL13	IL13, TH2LCRR	NA	NA	ENSG00000169194, ENSG00000223442	NA	NA	rs1295686-?	rs1295686	0	1295686	intron_variant	FALSE	NR	6e-10	9.221848749616356	NA	1.061	[1.041-1.080]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.061	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	1q23.3	1	161217875	FCER1G	FCER1G	NA	NA	ENSG00000158869	NA	NA	rs2070902-?	rs2070902	0	2070902	intron_variant	FALSE	NR	1e-9	9	NA	1.055	[1.037-1.073]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.055	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	8q21.13	8	80380364	TPD52, ZBTB10	NA - RNU6-1213P	NA	ENSG00000252884	NA	NA	25152	rs7824394-?	rs7824394	0	7824394	intron_variant	TRUE	NR	1e-9	9	NA	1.0504202	[1.03-1.07]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.0504202	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	3q28	3	188402113	LPP	LPP	NA	NA	ENSG00000145012	NA	NA	rs2030519-?	rs2030519	0	2030519	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	1.043	[1.028-1.059]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.043	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	15q22.33	15	67175947	SMAD3	SMAD3	NA	NA	ENSG00000166949	NA	NA	rs17294280-?	rs17294280	0	17294280	intron_variant	FALSE	NR	4e-8	7.3979400086720375	NA	1.053	[1.034-1.073]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.053	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	9q34.2	9	133266456	ABO	ABO, ABO	NA	NA	ENSG00000175164, ENSG00000281879	NA	NA	rs2519093-?	rs2519093	0	2519093	intron_variant	FALSE	NR	4e-8	7.3979400086720375	NA	1.055	[1.035-1.075]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.055	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	17q21.32	17	49250821	FLJ40194	FLJ40194	NA	NA	ENSG00000177369	NA	NA	rs28397663-?	rs28397663	0	28397663	intron_variant	FALSE	NR	4e-8	7.3979400086720375	NA	1.046	[1.029-1.062]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.046	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	12q13.3	12	57095926	STAT6	STAT6	NA	NA	ENSG00000166888	NA	NA	rs1059513-?	rs1059513	0	1059513	3_prime_UTR_variant	FALSE	NR	6e-7	6.221848749616356	NA	NA	NA	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Diastolic blood pressure	19,546 British ancestry individuals from 6863 families.	NA	3p26.3	3	1110752	CNTN6	CNTN6	NA	NA	ENSG00000134115	NA	NA	rs142892876-T	rs142892876	0	142892876	intron_variant	FALSE	0.001	5e-8	7.301029995663981	NA	10.688255	[6.85-14.53] mmHg increase	Illumina [24111857] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004203	Genome-wide genotyping array	0.001	10.688255	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Diastolic blood pressure	19,546 British ancestry individuals from 6863 families.	NA	3q29	3	193644588	OPA1	OPA1	NA	NA	ENSG00000198836	NA	NA	rs528908640-C	rs528908640	0	528908640	intron_variant	FALSE	5.0E-4	2e-8	7.698970004336019	NA	14.669373	[9.55-19.79] mmHg increase	Illumina [24111857] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004203	Genome-wide genotyping array	5e-4	14.669373	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Diastolic blood pressure	19,546 British ancestry individuals from 6863 families.	NA	9q31.2	9	107040156	intergenic	ZNF462 - NA	ENSG00000148143	NA	NA	26522	NA	rs568998724-A	rs568998724	0	568998724	intron_variant	TRUE	7.0E-4	3e-8	7.522878745280337	NA	13.491984	[8.72-18.26] mmHg increase	Illumina [24111857] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004203	Genome-wide genotyping array	7e-4	13.491984	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Diastolic blood pressure	19,546 British ancestry individuals from 6863 families.	NA	15q24.2	15	76002970	NRG4	NRG4	NA	NA	ENSG00000169752	NA	NA	rs187680191-T	rs187680191	0	187680191	intron_variant	FALSE	6.0E-4	3e-9	8.522878745280337	NA	18.580683	[12.44-24.72] mmHg increase	Illumina [24111857] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST004203	Genome-wide genotyping array	6e-4	18.580683	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	2q31.1	2	168906638	G6PC2	G6PC2, G6PC2, SPC25, SPC25	NA	NA	ENSG00000152254, ENSG00000278373, ENSG00000152253, ENSG00000277909	NA	NA	rs560887-C	rs560887	0	560887	intron_variant	FALSE	0.2907	6e-68	67.22184874961636	NA	0.22435525	[0.2-0.25] mmol/L increase	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.2907	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	3q26.2	3	171015287	SLC2A2	SLC2A2	NA	NA	ENSG00000163581	NA	NA	rs9873618-A	rs9873618	0	9873618	intron_variant	FALSE	0.2871	1e-11	11	NA	0.08893525	[0.063-0.115] mmol/L decrease	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.2871	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	7p13	7	44206254	YKT6	YKT6	NA	NA	ENSG00000106636	NA	NA	rs917793-T	rs917793	0	917793	intron_variant	FALSE	0.1831	3e-24	23.522878745280337	NA	0.15565135	[0.13-0.19] mmol/L increase	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.1831	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	8q24.11	8	117172544	SLC30A8	SLC30A8	NA	NA	ENSG00000164756	NA	NA	rs13266634-T	rs13266634	0	13266634	missense_variant	FALSE	0.3153	4e-11	10.397940008672037	NA	0.08332504	[0.059-0.108] mmol/L decrease	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.3153	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	10p15.2	10	3286126	intergenic	LINC02668 - NA	ENSG00000226762	NA	NA	27229	NA	rs533883198-A	rs533883198	0	533883198	intergenic_variant	TRUE	0.0027	4e-8	7.3979400086720375	NA	0.6832422	[0.44-0.93] mmol/L increase	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.0027	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	13q12.2	13	27925825	PDX1	PDX1	NA	NA	ENSG00000139515	NA	NA	rs7981781-A	rs7981781	0	7981781	3_prime_UTR_variant	FALSE	0.2337	1e-8	8	NA	0.07885604	[0.052-0.106] mmol/L increase	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.2337	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	21q22.3	21	42856322	WDR4	WDR4	NA	NA	ENSG00000160193	NA	NA	rs370189685-C	rs370189685	0	370189685	intron_variant	FALSE	0.0014	7e-9	8.154901959985743	NA	1.1757375	[0.78-1.57] mmol/L decrease	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.0014	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	1q32.3	1	213977478	intergenic	PROX1-AS1	NA	NA	ENSG00000230461	NA	NA	rs79687284-C	rs79687284	0	79687284	intron_variant	FALSE	0.0364	2e-8	7.698970004336019	(Non diabetics)	0.20430802	[0.13-0.28] mmol/L increase	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.0364	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	2p23.3	2	27518238	GCKR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs780095-G	rs780095	0	780095	intron_variant	FALSE	0.4267	8e-9	8.096910013008056	(Non diabetics)	0.070907116	[0.047-0.095] mmol/L increase	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.4267	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	2q31.1	2	168906638	G6PC2	G6PC2, G6PC2, SPC25, SPC25	NA	NA	ENSG00000152254, ENSG00000278373, ENSG00000152253, ENSG00000277909	NA	NA	rs560887-C	rs560887	0	560887	intron_variant	FALSE	0.2907	2e-75	74.69897000433602	(Non diabetics)	0.24374136	[0.22-0.27] mmol/L increase	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.2907	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	3q26.2	3	171007094	SLC2A2	SLC2A2	NA	NA	ENSG00000163581	NA	NA	rs8192675-C	rs8192675	0	8192675	intron_variant	FALSE	0.2839	8e-11	10.096910013008056	(Non diabetics)	0.087149106	[0.061-0.113] mmol/L decrease	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.2839	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	7p13	7	44206254	YKT6	YKT6	NA	NA	ENSG00000106636	NA	NA	rs917793-T	rs917793	0	917793	intron_variant	FALSE	0.1831	1e-28	28	(Non diabetics)	0.17493051	[0.14-0.21] mmol/L increase	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.1831	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	8q24.11	8	117173494	SLC30A8	SLC30A8	NA	NA	ENSG00000164756	NA	NA	rs11558471-G	rs11558471	0	11558471	3_prime_UTR_variant	FALSE	0.3227	5e-13	12.301029995663981	(Non diabetics)	0.0934751	[0.068-0.119] mmol/L decrease	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.3227	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	9q22.31	9	93420421	Y_RNA	Y_RNA - FAM120AOS	ENSG00000199964	ENSG00000188938	NA	2455	11020	rs143399767-C	rs143399767	0	143399767	intergenic_variant	TRUE	0.0108	1e-8	8	(Non diabetics)	0.36156827	[0.24-0.49] mmol/L increase	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.0108	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	13q12.2	13	27925825	PDX1	PDX1	NA	NA	ENSG00000139515	NA	NA	rs7981781-A	rs7981781	0	7981781	3_prime_UTR_variant	FALSE	0.2337	5e-10	9.301029995663981	(Non diabetics)	0.088977575	[0.061-0.117] mmol/L increase	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.2337	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Fasting plasma glucose	15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families.	NA	21q22.3	21	42856322	WDR4	WDR4	NA	NA	ENSG00000160193	NA	NA	rs370189685-?	rs370189685	0	370189685	intron_variant	FALSE	0.0014	3e-8	7.522878745280337	(Non diabetics)	1.1502396	[0.74-1.56] mmol/L decrease	Illumina [24111857] (imputed)	N	fasting blood glucose measurement	http://www.ebi.ac.uk/efo/EFO_0004465	GCST004206	Genome-wide genotyping array	0.0014	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	1p36.23	1	8173210	intergenic	NA - LINC01714	NA	ENSG00000227634	NA	NA	28308	rs149963466-A	rs149963466	0	149963466	TF_binding_site_variant	TRUE	0.0016	3e-8	7.522878745280337	NA	0.8677363	[0.56-1.18] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.0016	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	2p21	2	43028506	AC016735.2	LINC01819	NA	NA	ENSG00000231826	NA	NA	rs76183280-C	rs76183280	0	76183280	intron_variant	FALSE	0.0048	4e-8	7.3979400086720375	NA	0.4981176	[0.32-0.68] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.0048	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	8p23.1	8	9326086	RP-11-115 J16.1	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	38508	45004	rs4841132-G	rs4841132	0	4841132	non_coding_transcript_exon_variant	TRUE	0.0925	1e-8	8	NA	0.10894712	[0.072-0.146] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.0925	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	8p21.3	8	19967156	LPL	LPL	NA	NA	ENSG00000175445	NA	NA	rs15285-T	rs15285	0	15285	3_prime_UTR_variant	FALSE	0.2675	1e-18	18	NA	0.109238155	[0.085-0.134] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.2675	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	9q31.1	9	104899461	ABCA1	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs2740488-C	rs2740488	0	2740488	intron_variant	FALSE	0.2745	3e-8	7.522878745280337	NA	0.06913026	[0.045-0.093] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.2745	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	11q23.3	11	116830638	APOC3	APOC3	NA	NA	ENSG00000110245	NA	NA	rs138326449-A	rs138326449	0	138326449	splice_donor_variant	FALSE	0.0032	3e-20	19.522878745280337	NA	0.98099405	[0.77-1.19] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.0032	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	14q32.33	14	106368436	IGHVII-33-1	IGHVII-33-1 - IGHV3-33-2	ENSG00000282552	ENSG00000253440	NA	772	671	rs114529226-A	rs114529226	0	114529226	intergenic_variant	TRUE	0.0038	7e-9	8.154901959985743	NA	0.652583	[0.43-0.87] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.0038	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	15q21.3	15	58386521	ALDH1A2	ALDH1A2	NA	NA	ENSG00000128918	NA	NA	rs261290-C	rs261290	0	261290	intron_variant	FALSE	0.3442	3e-25	24.522878745280337	NA	0.121454455	[0.099-0.144] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.3442	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237	NA	14548	2511	rs3764261-A	rs3764261	0	3764261	regulatory_region_variant	TRUE	0.3261	1e-113	113	NA	0.26576465	[0.24-0.29] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.3261	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	16q22.1	16	67219616	LRRC29	LRRC29	NA	NA	ENSG00000125122	NA	NA	rs143264468-C	rs143264468	0	143264468	intron_variant	FALSE	0.001	2e-9	8.698970004336019	NA	1.1551353	[0.78-1.53] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.001	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	17q21.31	17	43848758	CD300LG	CD300LG	NA	NA	ENSG00000161649	NA	NA	rs72836561-T	rs72836561	0	72836561	missense_variant	FALSE	0.0294	2e-11	10.698970004336019	NA	0.23653477	[0.17-0.31] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.0294	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	18q21.1	18	49579658	LIPG	LIPG	NA	NA	ENSG00000101670	NA	NA	rs149615216-T	rs149615216	0	149615216	intron_variant	FALSE	0.0119	3e-9	8.522878745280337	NA	0.30159053	[0.2-0.4] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.0119	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	19p13.2	19	8364439	ANGPTL4	ANGPTL4	NA	NA	ENSG00000167772	NA	NA	rs116843064-A	rs116843064	0	116843064	missense_variant	FALSE	0.023	6e-10	9.221848749616356	NA	0.24762033	[0.17-0.33] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.023	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	19q13.32	19	44908822	APOE	APOE	NA	NA	ENSG00000130203	NA	NA	rs7412-T	rs7412	0	7412	missense_variant	FALSE	0.0779	6e-14	13.221848749616356	NA	0.1564597	[0.12-0.2] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.0779	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	19q13.42	19	54298734	LILRA3	MIR4752 - LILRA5	ENSG00000264703	ENSG00000187116	NA	16554	8336	rs453755-G	rs453755	0	453755	intron_variant	TRUE	0.248	3e-8	7.522878745280337	NA	0.073526785	[0.047-0.1] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.248	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	20q13.12	20	45909845	PLTP	PLTP	NA	NA	ENSG00000100979	NA	NA	rs435306-T	rs435306	0	435306	intron_variant	FALSE	0.2547	3e-8	7.522878745280337	NA	0.07017989	[0.045-0.095] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.2547	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	11q23.3	11	117183243	NR	SIDT2	NA	NA	ENSG00000149577	NA	NA	rs530885291-A	rs530885291	0	530885291	intron_variant	FALSE	NR	1e-19	19	NA	1.0283372	[0.81-1.25] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	NA	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	11q23.3	11	117349713	NR	CEP164	NA	NA	ENSG00000110274	NA	NA	rs192489212-C	rs192489212	0	192489212	intron_variant	FALSE	0.00173721	1e-9	9	NA	0.97264946	[0.66-1.28] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.00173721	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	16q13	16	56800342	NR	NUP93	NA	NA	ENSG00000102900	NA	NA	rs79600951-G	rs79600951	0	79600951	intron_variant	FALSE	0.0970784	4e-14	13.397940008672037	NA	0.14015938	[0.1-0.18] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.0970784	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	16q22.1	16	67542133	NR	RIPOR1	NA	NA	ENSG00000039523	NA	NA	rs183208454-T	rs183208454	0	183208454	synonymous_variant	FALSE	0.000761277	5e-9	8.301029995663981	NA	1.3088803	[0.87-1.75] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	7.61277e-4	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	16q22.1	16	67656785	NR	CARMIL2	NA	NA	ENSG00000159753	NA	NA	rs141279119-G	rs141279119	0	141279119	intron_variant	FALSE	0.000763783	7e-9	8.154901959985743	NA	1.3427596	[0.89-1.8] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	7.63783e-4	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	16q22.1	16	67970889	NR	SLC12A4 - DPEP3	ENSG00000124067	ENSG00000141096	NA	1288	4774	rs548291389-G	rs548291389	0	548291389	intergenic_variant	TRUE	0.000813701	1e-8	8	NA	1.2597599	[0.82-1.69] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	8.13701e-4	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	18q21.1	18	49227694	NR	DYM	NA	NA	ENSG00000141627	NA	NA	rs79943003-T	rs79943003	0	79943003	intron_variant	FALSE	0.011343	4e-8	7.3979400086720375	NA	0.30677906	[0.2-0.42] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.011343	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	18q21.1	18	49362269	NR	DYM	NA	NA	ENSG00000141627	NA	NA	rs192446476-C	rs192446476	0	192446476	intron_variant	FALSE	0.0117187	2e-8	7.698970004336019	NA	0.30899283	[0.2-0.42] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.0117187	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	20q13.12	20	45909845	NR	PLTP	NA	NA	ENSG00000100979	NA	NA	rs435306-T	rs435306	0	435306	intron_variant	FALSE	0.254704	3e-8	7.522878745280337	NA	0.07017989	[0.072-0.146] mg/dl decrease	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.254704	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	HDL cholesterol	19,223 British ancestry individuals from 6863 families.	NA	8p21.3	8	20071071	NR	NA - RPL30P9	NA	ENSG00000242709	NA	NA	42272	rs9644568-A	rs9644568	0	9644568	intergenic_variant	TRUE	0.254704	3e-14	13.522878745280337	NA	0.12829615	[0.095-0.161] mg/dl increase	Illumina [24111857] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004207	Genome-wide genotyping array	0.254704	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body mass index	19,900 British ancestry individuals from 6863 families.	NA	2p25.3	2	630075	intergenic	LINC01875 - TMEM18	ENSG00000225942	ENSG00000151353	NA	83408	33802	rs73139123-T	rs73139123	0	73139123	intergenic_variant	TRUE	0.183	1e-9	9	NA	0.08785722	[0.059-0.116] kg/m2 increase	Illumina [24111857] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004208	Genome-wide genotyping array	0.183	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body mass index	19,900 British ancestry individuals from 6863 families.	NA	2q36.3	2	227141539	COL4A4	COL4A4	NA	NA	ENSG00000081052	NA	NA	rs10498218-G	rs10498218	0	10498218	intron_variant	FALSE	0.00122179	4e-8	7.3979400086720375	NA	0.94184786	[0.61-1.28] kg/m2 decrease	Illumina [24111857] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004208	Genome-wide genotyping array	0.00122179	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body mass index	19,900 British ancestry individuals from 6863 families.	NA	15q14	15	39362080	RP11-624 L4.1	NA	NA	NA	NA	NA	NA	rs149913955-A	rs149913955	0	149913955	intron_variant	TRUE	0.0059	2e-8	7.698970004336019	NA	0.46256575	[0.3-0.62] kg/m2 decrease	Illumina [24111857] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004208	Genome-wide genotyping array	0.0059	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body mass index	19,900 British ancestry individuals from 6863 families.	NA	16p12.3	16	17083253	intergenic	NA - TCERG1P2	NA	ENSG00000260675	NA	NA	11098	rs571835655-A	rs571835655	0	571835655	non_coding_transcript_exon_variant	TRUE	0.0011	7e-9	8.154901959985743	NA	1.0599046	[0.7-1.42] kg/m2 decrease	Illumina [24111857] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004208	Genome-wide genotyping array	0.0011	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body mass index	19,900 British ancestry individuals from 6863 families.	NA	16q12.2	16	53775211	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs55872725-T	rs55872725	0	55872725	intron_variant	FALSE	0.3951	6e-21	20.221848749616356	NA	0.10437275	[0.083-0.126] kg/m2 increase	Illumina [24111857] (imputed)	N	body mass index	http://www.ebi.ac.uk/efo/EFO_0004340	GCST004208	Genome-wide genotyping array	0.3951	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	1p32.3	1	55039974	PCSK9	PCSK9	NA	NA	ENSG00000169174	NA	NA	rs11591147-T	rs11591147	0	11591147	missense_variant	FALSE	0.0169	2e-17	16.69897000433602	NA	0.36090583	[0.28-0.44] mg/dl decrease	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.0169	NA	0.36090583
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	1p31.3	1	62491359	DOCK7	DOCK7	NA	NA	ENSG00000116641	NA	NA	rs10889333-A	rs10889333	0	10889333	intron_variant	FALSE	0.3601	2e-10	9.698970004336019	NA	0.07188199	[0.05-0.094] mg/dl decrease	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.3601	NA	0.07188199
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	1p13.3	1	109274968	CELSR2	CELSR2	NA	NA	ENSG00000143126	NA	NA	rs12740374-T	rs12740374	0	12740374	3_prime_UTR_variant	FALSE	0.2288	8e-22	21.096910013008056	NA	0.12353132	[0.098-0.149] mg/dl decrease	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.2288	NA	0.12353132
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	2p24.1	2	21096144	intergenic	APOB - TDRD15	ENSG00000084674	ENSG00000218819	NA	52071	27824	rs672889-G	rs672889	0	672889	intron_variant	TRUE	0.1356	4e-16	15.397940008672037	NA	0.1294899	[0.098-0.161] mg/dl increase	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.1356	NA	0.1294899
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	2p21	2	43842633	ABCG8	ABCG8	NA	NA	ENSG00000143921	NA	NA	rs75331444-A	rs75331444	0	75331444	intron_variant	FALSE	0.072	2e-11	10.698970004336019	NA	0.14149597	[0.1-0.18] mg/dl decrease	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.072	NA	0.14149597
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	5q13.3	5	75360714	HMGCR	HMGCR, CERT1	NA	NA	ENSG00000113161, ENSG00000113163	NA	NA	rs12916-C	rs12916	0	12916	3_prime_UTR_variant	FALSE	0.397	6e-11	10.221848749616356	NA	0.07291148	[0.051-0.095] mg/dl increase	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.397	NA	0.07291148
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	6q25.3	6	160576086	LPA	LPA	NA	NA	ENSG00000198670	NA	NA	rs74617384-T	rs74617384	0	74617384	intron_variant	FALSE	0.0838	3e-9	8.522878745280337	NA	0.12114009	[0.081-0.161] mg/dl increase	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.0838	NA	0.12114009
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	8p23.1	8	9326154	RP11-115 J16.1	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	38576	44936	rs4841133-G	rs4841133	0	4841133	non_coding_transcript_exon_variant	TRUE	0.0929	3e-9	8.522878745280337	NA	0.11155177	[0.075-0.148] mg/dl increase	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.0929	NA	0.11155177
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	16q22.2	16	72074194	HPR	HPR, TXNL4B	NA	NA	ENSG00000261701, ENSG00000140830	NA	NA	rs2000999-A	rs2000999	0	2000999	intron_variant	FALSE	0.1776	7e-9	8.154901959985743	NA	0.082936555	[0.055-0.111] mg/dl increase	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.1776	NA	0.082936555
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	19p13.2	19	11083273	intergenic	SMARCA4 - LDLR	ENSG00000127616	ENSG00000130164	NA	3847	6189	rs10412048-G	rs10412048	0	10412048	intergenic_variant	TRUE	0.1086	5e-25	24.30102999566398	NA	0.18101913	[0.15-0.22] mg/dl decrease	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.1086	NA	0.18101913
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	19q13.32	19	44908822	APOE	APOE	NA	NA	ENSG00000130203	NA	NA	rs7412-T	rs7412	0	7412	missense_variant	FALSE	0.0779	5e-94	93.30102999566398	NA	0.41957754	[0.38-0.46] mg/dl decrease	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.0779	NA	0.41957754
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	1p31.3	1	62620326	NR	DOCK7	NA	NA	ENSG00000116641	NA	NA	rs12239736-A	rs12239736	0	12239736	intron_variant	FALSE	0.352174	4e-10	9.397940008672037	NA	0.07167609	[0.049-0.094] mg/dl decrease	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.352174	NA	0.07167609
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	2p24.1	2	21205417	NR	TDRD15 - NA	ENSG00000218819	NA	NA	61049	NA	rs71435601-G	rs71435601	0	71435601	intergenic_variant	TRUE	0.133847	4e-13	12.397940008672037	NA	0.11650893	[0.085-0.148] mg/dl decrease	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.133847	NA	0.11650893
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	5q13.3	5	75472522	NR	CERT1	NA	NA	ENSG00000113163	NA	NA	rs6873472-A	rs6873472	0	6873472	intron_variant	FALSE	0.377963	8e-9	8.096910013008056	NA	0.06486272	[0.043-0.087] mg/dl increase	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.377963	NA	0.06486272
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	5q13.3	5	75581978	NR	POLK	NA	NA	ENSG00000122008	NA	NA	rs5744672-C	rs5744672	0	5744672	non_coding_transcript_exon_variant	FALSE	0.378799	1e-8	8	NA	0.06437605	[0.042-0.086] mg/dl increase	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.378799	NA	0.06437605
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	19q13.32	19	45038524	NR	RELB - CLASRP	ENSG00000104856	ENSG00000104859	NA	326	521	rs34827707-A	rs34827707	0	34827707	regulatory_region_variant	TRUE	0.0340516	9e-17	16.045757490560675	NA	0.272045	[0.21-0.34] mg/dl decrease	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.0340516	NA	0.272045
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Cholesterol, total	19,259 British ancestry individuals from 6863 families.	NA	19q13.32	19	45169220	NR	TRAPPC6A, MARK4	NA	NA	ENSG00000007255, ENSG00000007047	NA	NA	rs149553138-A	rs149553138	0	149553138	intron_variant	FALSE	0.0366873	2e-10	9.698970004336019	NA	0.2052668	[0.14-0.27] mg/dl decrease	Illumina [24111857] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004209	Genome-wide genotyping array	0.0366873	NA	0.2052668
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body fat percentage	19,480 British ancestry individuals from 6863 families.	NA	1q31.2	1	192923945	intergenic	RN7SKP126 - ZNF101P2	ENSG00000223075	ENSG00000234473	NA	47960	69504	rs10921288-C	rs10921288	0	10921288	intron_variant	TRUE	0.0235	1e-8	8	NA	1.4656063	[0.96-1.97] % increase	Illumina [24111857] (imputed)	N	body fat percentage	http://www.ebi.ac.uk/efo/EFO_0007800	GCST004210	Genome-wide genotyping array	0.0235	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body fat percentage	19,480 British ancestry individuals from 6863 families.	NA	2q36.3	2	226795925	IRS1	IRS1	NA	NA	ENSG00000169047	NA	NA	rs142101835-G	rs142101835	0	142101835	synonymous_variant	FALSE	0.0022	3e-8	7.522878745280337	NA	5.5365014	[3.57-7.5] % increase	Illumina [24111857] (imputed)	N	body fat percentage	http://www.ebi.ac.uk/efo/EFO_0007800	GCST004210	Genome-wide genotyping array	0.0022	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body fat percentage	19,480 British ancestry individuals from 6863 families.	NA	5q13.3	5	77446790	WDR41	WDR41	NA	NA	ENSG00000164253	NA	NA	rs560546550-C	rs560546550	0	560546550	intron_variant	FALSE	7.0E-4	3e-9	8.522878745280337	NA	9.339747	[6.25-12.43] % decrease	Illumina [24111857] (imputed)	N	body fat percentage	http://www.ebi.ac.uk/efo/EFO_0007800	GCST004210	Genome-wide genotyping array	7e-4	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body fat percentage	19,480 British ancestry individuals from 6863 families.	NA	16p12.3	16	17083253	intergenic	NA - TCERG1P2	NA	ENSG00000260675	NA	NA	11098	rs571835655-A	rs571835655	0	571835655	non_coding_transcript_exon_variant	TRUE	0.0011	2e-8	7.698970004336019	NA	7.2517734	[4.72-9.79] % decrease	Illumina [24111857] (imputed)	N	body fat percentage	http://www.ebi.ac.uk/efo/EFO_0007800	GCST004210	Genome-wide genotyping array	0.0011	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body fat percentage	19,480 British ancestry individuals from 6863 families.	NA	16q12.2	16	53775211	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs55872725-T	rs55872725	0	55872725	intron_variant	FALSE	0.3951	6e-16	15.221848749616356	NA	0.6429834	[0.49-0.80] % increase	Illumina [24111857] (imputed)	N	body fat percentage	http://www.ebi.ac.uk/efo/EFO_0007800	GCST004210	Genome-wide genotyping array	0.3951	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Body fat percentage	19,480 British ancestry individuals from 6863 families.	NA	18q21.1	18	49311208	DYM	DYM	NA	NA	ENSG00000141627	NA	NA	rs141793746-T	rs141793746	0	141793746	intron_variant	FALSE	0.003	3e-8	7.522878745280337	NA	4.317551	[2.79-5.85] unit increase	Illumina [24111857] (imputed)	N	body fat percentage	http://www.ebi.ac.uk/efo/EFO_0007800	GCST004210	Genome-wide genotyping array	0.003	NA	NA
2017-06-21	28270201	Nagy R	2017-03-07	Genome Med	www.ncbi.nlm.nih.gov/pubmed/28270201	Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.	Urate levels	2077 British ancestry individuals from 6863 families.	NA	4p16.1	4	9992591	SLC2A9	SLC2A9	NA	NA	ENSG00000109667	NA	NA	rs6449213-T	rs6449213	0	6449213	intron_variant	FALSE	0.1652	2e-17	16.69897000433602	NA	NA	NA	Illumina [24111857] (imputed)	N	urate measurement	http://www.ebi.ac.uk/efo/EFO_0004531	GCST004211	Genome-wide genotyping array	0.1652	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	9q33.3	9	126514762	MVB12B, LMX1B	MVB12B - LMX1B	ENSG00000196814	ENSG00000136944	NA	7721	99166	rs62578082-?	rs62578082	0	62578082	regulatory_region_variant	TRUE	NR	1e-8	8	NA	1.14	[1.089-1.194]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.14	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	10q21.1	10	52440052	DKK1, MBL2	THAP12P3 - LNCAROD	ENSG00000227972	ENSG00000231131	NA	26560	10822	rs1194708-?	rs1194708	0	1194708	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	NA	1.098901	[1.06-1.14]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.098901	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	6p21.1	6	44783931	CDC5L, SUPT3H	NA - SUPT3H	NA	ENSG00000196284	NA	NA	25386	rs17336368-?	rs17336368	0	17336368	intron_variant	TRUE	NR	3e-8	7.522878745280337	NA	1.0928961	[1.06-1.13]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.0928961	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	6q16.1	6	94203856	EPHA7	NA	NA	NA	NA	NA	NA	rs112215522-?	rs112215522	0	112215522	intergenic_variant	TRUE	NR	4e-8	7.3979400086720375	NA	1.092	[1.058-1.127]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.092	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	15q13.3	15	32703267	SCG5, GREM1	SCG5 - GREM1	ENSG00000166922	ENSG00000282046	NA	6169	14737	rs6494598-?	rs6494598	0	6494598	intergenic_variant	TRUE	NR	6e-45	44.221848749616356	NA	1.222	[1.188-1.256]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.222	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	1q31.3	1	197381909	CRB1	CRB1	NA	NA	ENSG00000134376	NA	NA	rs2476023-?	rs2476023	0	2476023	intron_variant	FALSE	NR	1e-38	38	NA	1.2610341	[1.22-1.31]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.2610341	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	8q13.3	8	71124669	XKR9, EYA1	NA - EYA1	NA	ENSG00000104313	NA	NA	72764	rs10504499-?	rs10504499	0	10504499	intron_variant	TRUE	NR	8e-34	33.096910013008056	NA	1.292	[1.240-1.346]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.292	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	14q22.2	14	53788792	DDHD1, BMP4	LINC02331	NA	NA	ENSG00000235269	NA	NA	rs72678242-?	rs72678242	0	72678242	intron_variant	FALSE	NR	6e-32	31.221848749616356	NA	1.2738854	[1.22-1.32]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.2738854	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	2q22.3	2	144895720	ZEB2	TEX41	NA	NA	ENSG00000226674	NA	NA	rs17479393-?	rs17479393	0	17479393	intron_variant	FALSE	NR	8e-30	29.096910013008056	NA	1.201923	[1.17-1.24]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.201923	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	2q12.1	2	104015356	LOC100287010	LINC01965	NA	NA	ENSG00000256637	NA	NA	rs10175706-?	rs10175706	0	10175706	intron_variant	FALSE	NR	1e-27	27	NA	1.172333	[1.14-1.21]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.172333	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	20q12	20	39472902	DHX35	NA	NA	NA	NA	NA	NA	rs6028446-?	rs6028446	0	6028446	intergenic_variant	TRUE	NR	2e-22	21.69897000433602	NA	1.1481056	[1.12-1.18]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1481056	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	2q33.1	2	198801387	PLCL1, SATB2	NA	NA	NA	NA	NA	NA	rs13035389-?	rs13035389	0	13035389	intergenic_variant	TRUE	NR	7e-20	19.154901959985743	NA	1.139	[1.107-1.171]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.139	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	2q31.1	2	176507119	MTX2, HNRNPA3	LINC01117	NA	NA	ENSG00000224577	NA	NA	rs59156997-?	rs59156997	0	59156997	intron_variant	FALSE	NR	2e-19	18.69897000433602	NA	1.1990408	[1.15-1.25]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1990408	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	9p24.2	9	4290085	GLIS3	GLIS3	NA	NA	ENSG00000107249	NA	NA	rs4237150-?	rs4237150	0	4237150	intron_variant	FALSE	NR	6e-19	18.221848749616356	NA	1.1376565	[1.1-1.17]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1376565	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	2q36.1	2	222664393	FARSB, MOGAT1	FARSB - MOGAT1	ENSG00000116120	ENSG00000124003	NA	8301	7265	rs4674676-?	rs4674676	0	4674676	regulatory_region_variant	TRUE	NR	2e-17	16.69897000433602	NA	1.1890606	[1.14-1.24]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1890606	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	4q34.1	4	174150335	HAND2, FBXO8	LINC02268	NA	NA	ENSG00000248174	NA	NA	rs17275866-?	rs17275866	0	17275866	intron_variant	FALSE	NR	3e-17	16.522878745280337	NA	1.1428571	[1.11-1.18]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1428571	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	19q12	19	30491258	ZNF536	ZNF536	NA	NA	ENSG00000198597	NA	NA	rs55700449-?	rs55700449	0	55700449	intron_variant	FALSE	NR	3e-15	14.522878745280337	NA	1.1764705	[1.13-1.22]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1764705	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	4q34.3	4	176666086	SPCS3, VEGFC	NA - VEGFC	NA	ENSG00000150630	NA	NA	17452	rs12509218-?	rs12509218	0	12509218	intergenic_variant	TRUE	NR	3e-15	14.522878745280337	NA	1.1933174	[1.14-1.25]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1933174	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	2q22.3	2	143802452	ARHGAP15, GTDC1	ARHGAP15 - Y_RNA	ENSG00000075884	ENSG00000199964	NA	34100	94811	rs11688237-?	rs11688237	0	11688237	intron_variant	TRUE	NR	4e-15	14.397940008672037	NA	1.1185683	[1.09-1.15]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1185683	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	18q21.2	18	54988301	CCDC68, TCF4	CCDC68 - NA	ENSG00000166510	NA	NA	28840	NA	rs7243821-?	rs7243821	0	7243821	intergenic_variant	TRUE	NR	7e-15	14.154901959985743	NA	1.13	[1.096-1.165]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.13	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	17q24.1	17	65747532	CEP112	CEP112	NA	NA	ENSG00000154240	NA	NA	rs11650175-?	rs11650175	0	11650175	intron_variant	FALSE	NR	1e-14	14	NA	1.1223345	[1.09-1.16]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1223345	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	20p12.1	20	13533787	TASP1	TASP1	NA	NA	ENSG00000089123	NA	NA	rs2073323-?	rs2073323	0	2073323	intron_variant	FALSE	NR	6e-14	13.221848749616356	NA	1.129	[1.094-1.165]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.129	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	5q35.2	5	174733110	MSX2, DRD1	MSX2 - MIR4634	ENSG00000120149	ENSG00000266890	NA	2214	18624	rs4868444-?	rs4868444	0	4868444	intergenic_variant	TRUE	NR	7e-14	13.154901959985743	NA	1.187	[1.134-1.242]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.187	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	7q21.3	7	96514492	C7orf76, SHFM1	SEM1	NA	NA	ENSG00000127922	NA	NA	rs11768577-?	rs11768577	0	11768577	intron_variant	FALSE	NR	5e-56	55.30102999566398	NA	1.352	[1.303-1.402]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.352	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Allergy	66,973 European ancestry cases, 113,768 European ancestry controls	NA	2q12.1	2	102316052	IL1RL1	IL1RL1, IL18R1	NA	NA	ENSG00000115602, ENSG00000115604	NA	NA	rs950881-?	rs950881	0	950881	intron_variant	FALSE	NR	6e-27	26.221848749616356	NA	1.1235955	[1.1-1.15]	Illumina [12845910] (imputed)	N	allergy	http://www.ebi.ac.uk/efo/EFO_0003785	GCST003990	Genome-wide genotyping array	NA	1.1235955	NA
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	19q13.33	19	50870023	KLK2	KLK2	NA	NA	ENSG00000167751	NA	NA	rs2739472-?	rs2739472	0	2739472	intron_variant	FALSE	0.56	8e-10	9.096910013008056	(conditional on Round 6 SNPs)	0.034	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.56	NA	0.034
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	8p21.2	8	23609471	SLC25A37	RNU4-71P - SINHCAFP3	ENSG00000252067	ENSG00000253488	NA	9333	25405	rs4614003-?	rs4614003	0	4614003	intergenic_variant	TRUE	0.296	1e-15	15	(conditional on Round 1 SNPs)	0.05	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.296	NA	0.05
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	10q26.13	10	121572176	intergenic	FGFR2	NA	NA	ENSG00000066468	NA	NA	rs4752569-?	rs4752569	0	4752569	intron_variant	FALSE	0.503	1e-11	11	(conditional on Round 2 SNPs)	0.038	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.503	NA	0.038
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	8q24.21	8	127461280	intergenic	CASC8	NA	NA	ENSG00000246228	NA	NA	rs4871796-?	rs4871796	0	4871796	intron_variant	FALSE	0.073	4e-6	5.3979400086720375	(conditional on Round 2 SNPs)	0.048	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.073	NA	0.048
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	2p15	2	63050708	intergenic	OTX1	NA	NA	ENSG00000115507	NA	NA	rs58235267-?	rs58235267	0	58235267	intron_variant	FALSE	0.471	6e-7	6.221848749616356	(conditional on Round 2 SNPs)	0.027	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.471	NA	0.027
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	Xp22.2	X	16812550	TXLNG	TXLNG	NA	NA	ENSG00000086712	NA	NA	rs5969745-?	rs5969745	0	5969745	intron_variant	FALSE	0.6	3e-13	12.522878745280337	(conditional on Round 1 SNPs)	0.03	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.6	NA	0.03
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	NA	NA	NA	KLK2	NA	NA	NA	NA	NA	NA	rs6070-?	rs6070	0	6070	non_coding_transcript_exon_variant	TRUE	0.65	4e-16	15.397940008672037	(conditional on Round5 SNPs	0.048	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.65	NA	0.048
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	NA	NA	NA	KLK3	NA	NA	NA	NA	NA	NA	rs61752561-?	rs61752561	0	61752561	missense_variant	TRUE	0.97	2e-25	24.69897000433602	(conditional on Round 2 SNPs)	0.172	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.97	NA	0.172
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	16q23.2	16	79821935	intergenic	LINC01228	NA	NA	ENSG00000261082	NA	NA	rs66624999-?	rs66624999	0	66624999	intron_variant	FALSE	0.864	2e-7	6.698970004336019	(conditional on Round 2 SNPs)	0.04	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.864	NA	0.04
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	13q14.11	13	41321130	intergenic	NAA16	NA	NA	ENSG00000172766	NA	NA	rs74922337-?	rs74922337	0	74922337	intron_variant	FALSE	0.917	2e-7	6.698970004336019	(conditional on Round 1 SNPs)	0.055	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.917	NA	0.055
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	13q14.3	13	50507855	intergenic	DLEU1	NA	NA	ENSG00000176124	NA	NA	rs9596300-?	rs9596300	0	9596300	intron_variant	FALSE	0.853	1e-8	8	(conditional on Round 1 SNPs)	0.045	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.853	NA	0.045
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q23.3	1	161673195	FCGR2B	FCGR2B	NA	NA	ENSG00000072694	NA	NA	rs182968886-A	rs182968886	0	182968886	synonymous_variant	FALSE	0.116	7e-11	10.154901959985743	NA	0.03781338	[0.026-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.116	NA	0.03781338
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q23.3	1	162250328	NOS1AP	NOS1AP	NA	NA	ENSG00000198929	NA	NA	rs6677530-G	rs6677530	0	6677530	intron_variant	FALSE	0.1586	9e-12	11.045757490560675	NA	0.03324371	[0.024-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1586	NA	0.03324371
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q25.3	1	185439929	CTA-277P6.1	MCRIP2P2 - NA	ENSG00000270920	NA	NA	3882	NA	rs10732976-A	rs10732976	0	10732976	TF_binding_site_variant	TRUE	0.6935	2e-16	15.698970004336019	NA	0.03197058	[0.024-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.6935	NA	0.03197058
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q32.1	1	205774297	RAB7L1	RAB29	NA	NA	ENSG00000117280	NA	NA	rs823143-C	rs823143	0	823143	intron_variant	FALSE	0.4311	4e-10	9.397940008672037	NA	0.02229253	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.4311	NA	0.02229253
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q32.3	1	212249225	intergenic	LINC02608 - PPP2R5A	ENSG00000226251	ENSG00000066027	NA	10248	36185	rs1663626-A	rs1663626	0	1663626	intergenic_variant	TRUE	0.3975	4e-9	8.397940008672037	NA	0.02157876	[0.014-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3975	NA	0.02157876
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q41	1	220879448	HLX	HLX, HLX-AS1	NA	NA	ENSG00000136630, ENSG00000257551	NA	NA	rs796495740-C	rs796495740	1	67420025	5_prime_UTR_variant	FALSE	0.3296	1e-12	12	NA	0.02709785	[0.02-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3296	NA	0.02709785
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q42.3	1	234773551	intergenic	PP2672 - RNY4P16	ENSG00000279261	ENSG00000201638	NA	13495	64425	rs4626924-T	rs4626924	0	4626924	intergenic_variant	TRUE	0.5497	5e-19	18.30102999566398	NA	0.03237743	[0.025-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5497	NA	0.03237743
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q42.3	1	235941681	RP5-940F7.2	RNU6-968P - LINC02768	ENSG00000206803	ENSG00000229291	NA	26160	16198	rs9970896-T	rs9970896	0	9970896	intergenic_variant	TRUE	0.8876	1e-11	11	NA	0.03827854	[0.027-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.8876	NA	0.03827854
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	1q44	1	247264315	intergenic	VN1R5 - Y_RNA	ENSG00000197617	ENSG00000199964	NA	7105	30520	rs1578862-C	rs1578862	0	1578862	intergenic_variant	TRUE	0.38	5e-12	11.301029995663981	NA	0.02537002	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.38	NA	0.02537002
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2p25.1	2	8305030	LINC00299	LINC00299	NA	NA	ENSG00000236790	NA	NA	rs2630709-T	rs2630709	0	2630709	intron_variant	FALSE	0.517	4e-10	9.397940008672037	NA	0.02232225	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.517	NA	0.02232225
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2p23.3	2	24007763	MFSD2B	UBXN2A - MFSD2B	ENSG00000173960	ENSG00000205639	NA	2854	2318	rs56068891-G	rs56068891	0	56068891	intergenic_variant	TRUE	0.1356	4e-21	20.397940008672037	NA	0.04897646	[0.039-0.059] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1356	NA	0.04897646
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2p23.3	2	27526126	GCKR	GCKR - C2orf16	ENSG00000084734	ENSG00000221843	NA	2442	11260	rs11336847-A	rs11336847	0	11336847	intergenic_variant	TRUE	0.6166	1e-34	34	NA	0.04499914	[0.038-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.6166	NA	0.04499914
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2p21	2	43132926	intergenic	LINC02580 - ZFP36L2	ENSG00000230587	ENSG00000152518	NA	444	89476	rs28498283-T	rs28498283	0	28498283	regulatory_region_variant	TRUE	0.2601	6e-16	15.221848749616356	NA	0.03337007	[0.025-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2601	NA	0.03337007
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2p14	2	64690936	SERTAD2	SERTAD2	NA	NA	ENSG00000179833	NA	NA	rs3796051-T	rs3796051	0	3796051	intron_variant	FALSE	0.4677	9e-10	9.045757490560675	NA	0.02220913	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.4677	NA	0.02220913
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2p14	2	65438139	AC074391.1	SPRED2 - DNAJB12P1	ENSG00000198369	ENSG00000237979	NA	5502	62854	rs13417564-T	rs13417564	0	13417564	intron_variant	TRUE	0.5819	2e-12	11.698970004336019	NA	0.02546185	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5819	NA	0.02546185
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q13	2	110994574	ACOXL	ACOXL	NA	NA	ENSG00000153093	NA	NA	rs150449635-C	rs150449635	0	150449635	intron_variant	FALSE	0.024	1e-31	31	NA	0.1446111	[0.12-0.17] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.024	NA	0.1446111
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	NA	NA	NA	ACOXL	NA	NA	NA	NA	NA	NA	chr2:111753076-CAAAAAAAAA	chr2:111753076	0	NA	NA	TRUE	0.8788	3e-25	24.522878745280337	NA	0.05670317	[0.046-0.067] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.8788	NA	0.05670317
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q13	2	111029060	ACOXL	ACOXL, MIR4435-2HG	NA	NA	ENSG00000153093, ENSG00000172965	NA	NA	rs56068469-G	rs56068469	0	56068469	intron_variant	FALSE	0.1656	2e-21	20.69897000433602	NA	0.04544254	[0.036-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1656	NA	0.04544254
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q13	2	111119036	BCL2L11, AC096670.3	ACOXL, MIR4435-2HG	NA	NA	ENSG00000153093, ENSG00000172965	NA	NA	rs72836346-C	rs72836346	0	72836346	3_prime_UTR_variant	FALSE	0.0801	2e-12	11.698970004336019	NA	0.04839354	[0.035-0.062] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0801	NA	0.04839354
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q13	2	111153117	BCL2L11	MIR4435-2HG, BCL2L11	NA	NA	ENSG00000172965, ENSG00000153094	NA	NA	rs6734942-T	rs6734942	0	6734942	intron_variant	FALSE	0.3832	2e-21	20.69897000433602	NA	0.03484736	[0.028-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3832	NA	0.03484736
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	NA	NA	NA	intergenic	NA	NA	NA	NA	NA	NA	chr2:127879500-CTTG	chr2:127879500	0	NA	NA	TRUE	0.0559	2e-9	8.698970004336019	NA	0.0458984	[0.031-0.061] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0559	NA	0.0458984
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q22.1	2	136134595	intergenic	CXCR4 - HNRNPKP2	ENSG00000121966	ENSG00000227347	NA	16446	64519	rs1818690-G	rs1818690	0	1818690	regulatory_region_variant	TRUE	0.7358	1e-33	33	NA	0.04872256	[0.041-0.057] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.7358	NA	0.04872256
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q24.2	2	159649241	intergenic	BAZ2B - RPS3AP13	ENSG00000123636	ENSG00000230783	NA	32672	39976	rs4664293-C	rs4664293	0	4664293	intergenic_variant	TRUE	0.375	1e-23	23	NA	0.03685898	[0.03-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.375	NA	0.03685898
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q24.2	2	160476617	RBMS1	RBMS1	NA	NA	ENSG00000153250	NA	NA	rs4664330-C	rs4664330	0	4664330	intron_variant	FALSE	0.3146	3e-10	9.522878745280337	NA	0.02421946	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3146	NA	0.02421946
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q31.3	2	181459460	ITGA4	ITGA4	NA	NA	ENSG00000115232	NA	NA	rs10562650-C	rs10562650	0	10562650	intron_variant	FALSE	0.5555	1e-222	222	NA	0.1143897	[0.11-0.12] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5555	NA	0.1143897
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q35	2	218135259	CXCR2	CXCR2	NA	NA	ENSG00000180871	NA	NA	rs55799208-A	rs55799208	0	55799208	missense_variant	FALSE	0.0029	5e-11	10.301029995663981	NA	0.2343691	[0.16-0.3] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0029	NA	0.2343691
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q35	2	218156235	intergenic	CXCR2 - CXCR1	ENSG00000180871	ENSG00000163464	NA	18984	6606	rs114050631-T	rs114050631	0	114050631	regulatory_region_variant	TRUE	0.0106	7e-10	9.154901959985743	NA	0.1189524	[0.081-0.157] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0106	NA	0.1189524
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q36.2	2	224886036	DOCK10	DOCK10	NA	NA	ENSG00000135905	NA	NA	rs10197805-C	rs10197805	0	10197805	intron_variant	FALSE	0.1555	3e-16	15.522878745280337	NA	0.04037798	[0.031-0.05] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1555	NA	0.04037798
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	2q36.3	2	226423002	intergenic	NA	NA	NA	NA	NA	NA	rs35669853-A	rs35669853	0	35669853	intergenic_variant	TRUE	0.1948	4e-9	8.397940008672037	NA	0.02665776	[0.018-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1948	NA	0.02665776
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	NA	NA	NA	GPR35	NA	NA	NA	NA	NA	NA	chr2:241569329-G	chr2:241569329	0	NA	NA	TRUE	0.5435	8e-10	9.096910013008056	NA	0.02191896	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5435	NA	0.02191896
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3p22.2	3	39265671	CX3CR1	CX3CR1	NA	NA	ENSG00000168329	NA	NA	rs3732378-A	rs3732378	0	3732378	missense_variant	FALSE	0.1737	1e-24	24	NA	0.0479132	[0.039-0.057] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1737	NA	0.0479132
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3p22.1	3	42864023	CYP8B1, KRBOX1, ACKR2, RP11-141M3.5	CYP8B1, ACKR2, KRBOX1	NA	NA	ENSG00000180432, ENSG00000144648, ENSG00000240747	NA	NA	rs4682868-T	rs4682868	0	4682868	intron_variant	FALSE	0.3869	8e-38	37.096910013008056	NA	0.04686022	[0.04-0.054] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3869	NA	0.04686022
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3p22.1	3	42864624	ACKR2	ACKR2, CYP8B1, KRBOX1	NA	NA	ENSG00000144648, ENSG00000180432, ENSG00000240747	NA	NA	rs2228467-C	rs2228467	0	2228467	missense_variant	FALSE	0.0615	1e-97	97	NA	0.1552617	[0.14-0.17] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0615	NA	0.1552617
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3p21.31	3	46364876	CCR2, RP11-24F11.2	CCR2 - CCR5AS	ENSG00000121807	ENSG00000223552	NA	3936	79	rs2213290-T	rs2213290	0	2213290	intergenic_variant	TRUE	0.4084	1e-33	33	NA	0.04394357	[0.037-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.4084	NA	0.04394357
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3p21.31	3	46408487	CCRL2	CCRL2	NA	NA	ENSG00000121797	NA	NA	rs11266744-C	rs11266744	0	11266744	synonymous_variant	FALSE	0.3957	3e-9	8.522878745280337	NA	0.02164235	[0.014-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3957	NA	0.02164235
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3p21.31	3	46421418	intergenic	LINC02009	NA	NA	ENSG00000283646	NA	NA	rs34042186-A	rs34042186	0	34042186	splice_region_variant	FALSE	0.1257	3e-23	22.522878745280337	NA	0.05381013	[0.043-0.064] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1257	NA	0.05381013
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3p21.31	3	47029484	SETD2	SETD2	NA	NA	ENSG00000181555	NA	NA	rs543811905-CA	rs543811905	1	56191823	intron_variant	FALSE	0.1786	6e-10	9.221848749616356	NA	0.0304442	[0.021-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1786	NA	0.0304442
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3p13	3	71722065	EIF4E3	EIF4E3	NA	NA	ENSG00000163412	NA	NA	rs34778241-TG	rs34778241	0	34778241	intron_variant	FALSE	0.6176	2e-14	13.698970004336019	NA	0.03031825	[0.023-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.6176	NA	0.03031825
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3q21.3	3	128586459	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	10373	33510	rs2010054-G	rs2010054	0	2010054	regulatory_region_variant	TRUE	0.5947	4e-123	122.39794000867204	NA	0.08513893	[0.078-0.092] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5947	NA	0.08513893
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3q21.3	3	128587575	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	11489	32394	rs6772849-C	rs6772849	0	6772849	intergenic_variant	TRUE	0.3537	3e-112	111.52287874528034	NA	0.08361036	[0.076-0.091] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3537	NA	0.08361036
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3q21.3	3	128630533	RPN1	RPN1	NA	NA	ENSG00000163902	NA	NA	rs55683935-G	rs55683935	0	55683935	intron_variant	FALSE	0.0388	9e-33	32.045757490560675	NA	0.1097044	[0.092-0.128] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0388	NA	0.1097044
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3q23	3	141573776	RASA2	RASA2	NA	NA	ENSG00000155903	NA	NA	rs1493209-A	rs1493209	0	1493209	intron_variant	FALSE	0.3997	3e-18	17.522878745280337	NA	0.03171889	[0.025-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3997	NA	0.03171889
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3q26.31	3	172516227	TNFSF10	TNFSF10	NA	NA	ENSG00000121858	NA	NA	rs142552223-A	rs142552223	0	142552223	intron_variant	FALSE	0.0402	5e-9	8.301029995663981	NA	0.05353311	[0.036-0.072] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0402	NA	0.05353311
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	3q28	3	188417995	LPP	LPP	NA	NA	ENSG00000145012	NA	NA	rs12485444-A	rs12485444	0	12485444	intron_variant	FALSE	0.5392	5e-14	13.301029995663981	NA	0.028056	[0.021-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5392	NA	0.028056
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	4p16.3	4	725926	PCGF3	PCGF3	NA	NA	ENSG00000185619	NA	NA	rs4690295-G	rs4690295	0	4690295	intron_variant	FALSE	0.3151	2e-10	9.698970004336019	NA	0.02426741	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3151	NA	0.02426741
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	4p16.1	4	6919697	TBC1D14	TBC1D14	NA	NA	ENSG00000132405	NA	NA	rs10937764-C	rs10937764	0	10937764	intron_variant	FALSE	0.9035	8e-18	17.096910013008056	NA	0.0538722	[0.042-0.066] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.9035	NA	0.0538722
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	4p16.1	4	7078598	intergenic	GRPEL1 - LINC02447	ENSG00000109519	ENSG00000245468	NA	10534	15178	rs4689592-T	rs4689592	0	4689592	intergenic_variant	TRUE	0.1824	1e-11	11	NA	0.03147556	[0.022-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1824	NA	0.03147556
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	4p14	4	38367014	RP11-83C7.1	LINC02513	NA	NA	ENSG00000248227	NA	NA	rs901705-G	rs901705	0	901705	non_coding_transcript_exon_variant	FALSE	0.6807	2e-14	13.698970004336019	NA	0.0291822	[0.022-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.6807	NA	0.0291822
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	4q13.3	4	73838282	CXCL6	CXCL6	NA	NA	ENSG00000124875	NA	NA	rs16850073-T	rs16850073	0	16850073	3_prime_UTR_variant	FALSE	0.3749	5e-13	12.301029995663981	NA	0.02675622	[0.02-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3749	NA	0.02675622
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	4q13.3	4	74094279	CXCL2	PPBPP2 - CXCL2	ENSG00000248848	ENSG00000081041	NA	38880	2761	rs11725704-G	rs11725704	0	11725704	regulatory_region_variant	TRUE	0.3763	1e-24	24	NA	0.03774749	[0.031-0.045] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3763	NA	0.03774749
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q21.2	10	61764833	C10orf107	CABCOCO1	NA	NA	ENSG00000183346	NA	NA	rs1530440-C	rs1530440	0	1530440	intron_variant	FALSE	NA	7e-11	10.154901959985743	NA	0.316	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6p21.1	6	43340625	ZNF318	ZNF318	NA	NA	ENSG00000171467	NA	NA	rs1563788-C	rs1563788	0	1563788	intron_variant	FALSE	NA	4e-10	9.397940008672037	NA	0.258	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q22.31	6	118291780	SLC35F1	SLC35F1	NA	NA	ENSG00000196376	NA	NA	rs1630266-G	rs1630266	0	1630266	intron_variant	FALSE	NA	2e-6	5.698970004336019	NA	0.333	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	19p13.2	19	11416089	RGL3	RGL3	NA	NA	ENSG00000205517	NA	NA	rs167479-G	rs167479	0	167479	missense_variant	FALSE	NA	2e-21	20.69897000433602	NA	0.41	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q21.1	15	48607900	NR	FBN1	NA	NA	ENSG00000166147	NA	NA	rs1678981-C	rs1678981	0	1678981	intron_variant	FALSE	NA	4e-10	9.397940008672037	NA	0.405	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q24.3	2	164050310	FIGN, GRB14	NA	NA	NA	NA	NA	NA	rs16849225-C	rs16849225	0	16849225	intron_variant	TRUE	NA	2e-19	18.69897000433602	NA	0.402	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q11.2	5	51640066	ISL1, PELO	LINC02103 - NA	ENSG00000249785	NA	NA	23352259	NA	rs168643-T	rs168643	0	168643	intron_variant	TRUE	NA	9e-7	6.045757490560675	NA	0.196	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q11.2	5	53987800	ARL15	ARL15	NA	NA	ENSG00000185305	NA	NA	rs1694068-T	rs1694068	0	1694068	intron_variant	FALSE	NA	7e-10	9.154901959985743	NA	0.245	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17q21.33	17	49363104	ZNF652, PHB	ZNF652 - PHB	ENSG00000198740	ENSG00000167085	NA	631	40948	rs16948048-A	rs16948048	0	16948048	intron_variant	TRUE	NA	5e-12	11.301029995663981	NA	0.271	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q21.21	4	80263187	PRDM8, FGF5	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675	NA	58858	3452	rs16998073-A	rs16998073	0	16998073	intergenic_variant	TRUE	NA	2e-53	52.69897000433602	NA	0.66	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q25.1	6	150683634	PLEKHG1	PLEKHG1	NA	NA	ENSG00000120278	NA	NA	rs17080102-G	rs17080102	0	17080102	5_prime_UTR_variant	FALSE	NA	5e-16	15.301029995663981	NA	0.593	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q14.3	5	92565078	ARRDC3-AS1, FLJ42709	NA	NA	NA	NA	NA	NA	rs17082391-C	rs17082391	0	17082391	intron_variant	TRUE	NA	5e-7	6.301029995663981	NA	0.544	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q13.12	12	50662728	DIP2B	DIP2B	NA	NA	ENSG00000066084	NA	NA	rs17210898-G	rs17210898	0	17210898	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.556	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q14.3	5	88134485	CCNH, TMEM161B	NA - TMEM161B	NA	ENSG00000164180	NA	NA	55148	rs17286052-A	rs17286052	0	17286052	intron_variant	TRUE	NA	7e-11	10.154901959985743	NA	0.36	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p36.22	1	11802721	MTHFR	MTHFR	NA	NA	ENSG00000177000	NA	NA	rs17367504-A	rs17367504	0	17367504	intron_variant	FALSE	NA	1e-40	40	NA	0.695	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q31.1	7	108449811	NRCAM	NRCAM	NA	NA	ENSG00000091129	NA	NA	rs17423264-C	rs17423264	0	17423264	intron_variant	FALSE	NA	5e-8	7.301029995663981	NA	0.366	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7p15.2	7	27298248	EVX1, HIBADH	RPL35P4 - HNRNPA1P73	ENSG00000213783	ENSG00000236569	NA	28570	30359	rs17428471-G	rs17428471	0	17428471	intergenic_variant	TRUE	NA	3e-12	11.522878745280337	NA	0.486	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4p11	4	48299674	TEC, SLAIN2	TEC - SLAIN2	ENSG00000135605	ENSG00000109171	NA	29836	41855	rs17471509-A	rs17471509	0	17471509	intergenic_variant	TRUE	NA	9e-7	6.045757490560675	NA	0.191	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q22.3	7	106771412	CCDC71L, PIK3CG	LINC01446 - LINC02577	ENSG00000205628	ENSG00000228742	NA	52959460	3543	rs17477177-T	rs17477177	0	17477177	intergenic_variant	TRUE	NA	3e-36	35.52287874528034	NA	0.594	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17q21.32	17	46935905	GOSR2	GOSR2	NA	NA	ENSG00000108433	NA	NA	rs17608766-T	rs17608766	0	17608766	3_prime_UTR_variant	FALSE	NA	2e-27	26.69897000433602	NA	0.616	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q24.13	12	112153882	NR	TRAFD1 - HECTD4	ENSG00000135148	ENSG00000173064	NA	278	6306	rs17630235-G	rs17630235	0	17630235	intergenic_variant	TRUE	NA	5e-18	17.30102999566398	NA	0.34	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p14.1	3	66386662	LRIG1	SLC25A26, SLC25A26, LRIG1	NA	NA	ENSG00000282739, ENSG00000144741, ENSG00000144749	NA	NA	rs17831815-T	rs17831815	0	17831815	3_prime_UTR_variant	FALSE	NA	4e-7	6.3979400086720375	NA	0.203	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6p22.2	6	26090951	HFE	HFE	NA	NA	ENSG00000010704	NA	NA	rs1799945-C	rs1799945	0	1799945	missense_variant	FALSE	NA	4e-11	10.397940008672037	NA	0.359	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q25.3	10	114045297	ADRB1	ADRB1	NA	NA	ENSG00000043591	NA	NA	rs1801253-G	rs1801253	0	1801253	missense_variant	FALSE	NA	2e-10	9.698970004336019	NA	0.273	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q21.2	10	62793174	ZNF365, ADO	ALDH7A1P4 - ADO	ENSG00000234489	ENSG00000181915	NA	51789	11546	rs1848797-A	rs1848797	0	1848797	intron_variant	TRUE	NA	1e-11	11	NA	0.265	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5p15.2	5	10860374	DAP, CTNND2	DAP-DT - NA	ENSG00000272324	NA	NA	90080	NA	rs185695143-C	rs185695143	0	185695143	regulatory_region_variant	TRUE	NA	3e-8	7.522878745280337	NA	20.232	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p13.2	2	72887223	EXOC6B, SPR	EXOC6B - SPR	ENSG00000144036	ENSG00000116096	NA	61182	159	rs1876487-A	rs1876487	0	1876487	TF_binding_site_variant	TRUE	NA	4e-6	5.3979400086720375	NA	0.205	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q31.22	4	147472512	TTC29, EDNRA	PRMT5P1 - EDNRA	ENSG00000249004	ENSG00000151617	NA	13191	8405	rs1878406-C	rs1878406	0	1878406	intergenic_variant	TRUE	NA	2e-9	8.698970004336019	NA	0.321	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q12.1	11	58646437	CNTF, GLYAT	GLYAT	NA	NA	ENSG00000149124	NA	NA	rs1938598-T	rs1938598	0	1938598	intron_variant	FALSE	NA	1e-13	13	NA	0.33	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1q42.2	1	230712956	AGT	AGT	NA	NA	ENSG00000135744	NA	NA	rs2004776-C	rs2004776	0	2004776	intron_variant	FALSE	NA	1e-9	9	NA	0.265	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16p12.1	16	24721820	RBBP6, TNRC6A	TNRC6A	NA	NA	ENSG00000090905	NA	NA	rs200541-A	rs200541	0	200541	intron_variant	FALSE	NA	9e-9	8.045757490560675	NA	0.281	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	22q11.21	22	19990124	ARVCF	ARVCF	NA	NA	ENSG00000099889	NA	NA	rs2012714-C	rs2012714	0	2012714	intron_variant	FALSE	NA	1e-6	6	NA	0.222	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q21.23	4	85794517	ARHGAP24	ARHGAP24	NA	NA	ENSG00000138639	NA	NA	rs2014912-T	rs2014912	0	2014912	intron_variant	FALSE	NA	4e-7	6.3979400086720375	NA	0.269	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	6q14.1	6	79043677	PHIP	PHIP	NA	NA	ENSG00000146247	NA	NA	rs2050663-T	rs2050663	0	2050663	intron_variant	FALSE	NA	4e-9	8.397940008672037	NA	0.229	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q24.12	8	119423572	NOV	CCN3	NA	NA	ENSG00000136999	NA	NA	rs2071518-C	rs2071518	0	2071518	3_prime_UTR_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.199	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7p21.1	7	19009765	HDAC9, TWIST1	HDAC9 - TWIST1	ENSG00000048052	ENSG00000122691	NA	7349	11226	rs2107595-G	rs2107595	0	2107595	regulatory_region_variant	TRUE	NA	9e-14	13.045757490560675	NA	0.379	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.5	11	1995678	H19	H19	NA	NA	ENSG00000130600	NA	NA	rs217727-G	rs217727	0	217727	non_coding_transcript_exon_variant	FALSE	NA	1e-9	9	NA	0.339	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q25.33	3	160652372	SCARNA7, ARL14	RPL6P8 - ARL14	ENSG00000242285	ENSG00000179674	NA	66585	24788	rs2178452-G	rs2178452	0	2178452	intergenic_variant	TRUE	NA	1e-10	10	NA	0.259	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	18q12.3	18	45516271	SLC14A2	SLC14A2	NA	NA	ENSG00000132874	NA	NA	rs2193635-C	rs2193635	0	2193635	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.274	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p21.31	3	50436853	CACNA2D2	CACNA2D2	NA	NA	ENSG00000007402	NA	NA	rs2236973-T	rs2236973	0	2236973	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.255	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17q23.2	17	61408032	TBX2	TBX2, TBX2-AS1	NA	NA	ENSG00000121068, ENSG00000267280	NA	NA	rs2240736-C	rs2240736	0	2240736	non_coding_transcript_exon_variant	FALSE	NA	1e-10	10	NA	0.286	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q21.2	7	92635096	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs2282978-T	rs2282978	0	2282978	intron_variant	FALSE	NA	5e-11	10.301029995663981	NA	0.264	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q14.3	11	89491285	NOX4	NOX4	NA	NA	ENSG00000086991	NA	NA	rs2289125-A	rs2289125	0	2289125	5_prime_UTR_variant	FALSE	NA	2e-9	8.698970004336019	NA	0.274	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q13.1	11	65638129	NR	SIPA1	NA	NA	ENSG00000213445	NA	NA	rs2306363-G	rs2306363	0	2306363	5_prime_UTR_variant	FALSE	NA	4e-13	12.397940008672037	NA	0.355	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q33.3	2	207544615	CREB1	CREB1	NA	NA	ENSG00000118260	NA	NA	rs2360970-G	rs2360970	0	2360970	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.215	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q24.21	12	114914926	TBX3, MIR620	NA	NA	NA	NA	NA	NA	rs2384550-G	rs2384550	0	2384550	regulatory_region_variant	TRUE	NA	3e-7	6.522878745280337	NA	0.204	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p32.2	1	56543106	PPAP2B	PLPP3	NA	NA	ENSG00000162407	NA	NA	rs2404715-C	rs2404715	0	2404715	intron_variant	FALSE	NA	2e-9	8.698970004336019	NA	0.4	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	10q21.2	10	59879046	CCDC6	CCDC6	NA	NA	ENSG00000108091	NA	NA	rs2440907-G	rs2440907	0	2440907	intron_variant	FALSE	NA	2e-7	6.698970004336019	NA	0.199	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	15q26.1	15	90894158	FES	FES	NA	NA	ENSG00000182511	NA	NA	rs2521501-A	rs2521501	0	2521501	intron_variant	FALSE	NA	2e-26	25.69897000433602	NA	0.497	unit decrease	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2p14	2	65052089	SLC1A4, CEP68	LINC02245, LINC02576	NA	NA	ENSG00000237638, ENSG00000232613	NA	NA	rs2540950-C	rs2540950	0	2540950	intron_variant	FALSE	NA	9e-7	6.045757490560675	NA	0.193	unit increase	Affymetrix [at least 2696785] (imputed)	N	systolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006335	GCST007099	Genome-wide genotyping array	NA	NA	NA
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	9q31.1	9	104902020	ABCA1	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs1883025-T	rs1883025	0	1883025	intron_variant	FALSE	0.243	7e-85	84.15490195998575	(Trans-ethnic initial)	0.0698	[0.062-0.078] unit decrease (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.243	NA	0.0698
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	18q21.1	18	49655298	LIPG	SMUG1P1 - ACAA2	ENSG00000267444	ENSG00000167315	NA	4138	126866	rs2156552-A	rs2156552	0	2156552	intergenic_variant	TRUE	0.178	2e-74	73.69897000433602	(Trans-ethnic initial)	0.0793	[0.07-0.088] unit decrease (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.178	NA	0.0793
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	11q23.3	11	116792991	APOA1, APOC3, APOA4, APOA5	APOA5 - APOA4	ENSG00000110243	ENSG00000110244	NA	571	27709	rs662799-A	rs662799	0	662799	intergenic_variant	TRUE	0.92	3e-71	70.52287874528034	(Trans-ethnic initial)	0.1	[0.086-0.114] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.92	NA	0.1
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	16q22.1	16	67951803	LCAT	SLC12A4	NA	NA	ENSG00000124067	NA	NA	rs2292318-T	rs2292318	0	2292318	intron_variant	FALSE	0.141	3e-57	56.52287874528034	(Trans-ethnic initial)	0.0805	[0.071-0.09] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.141	NA	0.0805
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	1q42.13	1	230159944	GALNT2	GALNT2	NA	NA	ENSG00000143641	NA	NA	rs4846914-A	rs4846914	0	4846914	intron_variant	FALSE	0.584	2e-44	43.69897000433602	(Trans-ethnic initial)	0.0479	[0.041-0.055] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.584	NA	0.0479
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	8p23.1	8	9326721	PPP1R3B	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	39143	44369	rs4240624-A	rs4240624	0	4240624	intron_variant	TRUE	0.925	1e-42	42	(Trans-ethnic initial)	0.0818	[0.07-0.093] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.925	NA	0.0818
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	20q13.12	20	45925376	PLTP	PLTP - PCIF1	ENSG00000100979	ENSG00000100982	NA	13221	9307	rs6065906-T	rs6065906	0	6065906	regulatory_region_variant	TRUE	0.802	6e-39	38.221848749616356	(Trans-ethnic initial)	0.0594	[0.051-0.068] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.802	NA	0.0594
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	11p11.2	11	47276809	LRP4	MADD	NA	NA	ENSG00000110514	NA	NA	rs326214-A	rs326214	0	326214	synonymous_variant	FALSE	0.686	6e-39	38.221848749616356	(Trans-ethnic initial)	0.0609	[0.052-0.07] unit decrease (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.686	NA	0.0609
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	12q24.31	12	124777047	SCARB1	SCARB1	NA	NA	ENSG00000073060	NA	NA	rs838880-T	rs838880	0	838880	3_prime_UTR_variant	FALSE	0.674	1e-34	34	(Trans-ethnic initial)	0.0484	[0.041-0.056] unit decrease (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.674	NA	0.0484
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	12q24.31	12	124777047	ZNF664	SCARB1	NA	NA	ENSG00000073060	NA	NA	rs838880-T	rs838880	0	838880	3_prime_UTR_variant	FALSE	0.674	1e-34	34	(Trans-ethnic initial)	0.0484	[0.041-0.056] unit decrease (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.674	NA	0.0484
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	19q13.32	19	44919689	APOE, APOC1, APOC2	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855	NA	340	7115	rs4420638-A	rs4420638	0	4420638	regulatory_region_variant	TRUE	0.814	6e-34	33.221848749616356	(Trans-ethnic initial)	0.0669	[0.054-0.08] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.814	NA	0.0669
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	19q13.42	19	54293995	LILRA3	MIR4752 - LILRA5	ENSG00000264703	ENSG00000187116	NA	11815	13075	rs103294-T	rs103294	0	103294	3_prime_UTR_variant	TRUE	0.186	5e-30	29.30102999566398	(Trans-ethnic initial)	0.0523	[0.044-0.061] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.186	NA	0.0523
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	11q12.2	11	61804006	FADS1, FADS2, FADS3	FADS2, FADS1	NA	NA	ENSG00000134824, ENSG00000149485	NA	NA	rs174550-T	rs174550	0	174550	5_prime_UTR_variant	FALSE	0.642	6e-30	29.221848749616356	(Trans-ethnic initial)	0.039	[0.032-0.046] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.642	NA	0.039
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	8q24.13	8	125483576	TRIB1	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	45173	376145	rs10808546-T	rs10808546	0	10808546	intron_variant	TRUE	0.446	1e-26	26	(Trans-ethnic initial)	0.0409	[0.034-0.048] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.446	NA	0.0409
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	12q24.11	12	109512339	MVK	UBE3B	NA	NA	ENSG00000151148	NA	NA	rs2241210-A	rs2241210	0	2241210	intron_variant	FALSE	0.447	8e-24	23.096910013008056	(Trans-ethnic initial)	0.0332	[0.026-0.04] unit decrease (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.447	NA	0.0332
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	22q11.21	22	21574627	UBE2L3	UBE2L3	NA	NA	ENSG00000185651	NA	NA	rs181360-T	rs181360	0	181360	intron_variant	FALSE	0.801	1e-22	22	(Trans-ethnic initial)	0.0376	[0.029-0.046] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.801	NA	0.0376
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	1q25.3	1	182181843	ZNF648	LINC01344	NA	NA	ENSG00000228918	NA	NA	rs1689797-A	rs1689797	0	1689797	intron_variant	FALSE	0.302	8e-22	21.096910013008056	(Trans-ethnic initial)	0.0358	[0.029-0.043] unit decrease (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.302	NA	0.0358
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	16q23.2	16	81501185	CMIP	CMIP	NA	NA	ENSG00000153815	NA	NA	rs2925979-T	rs2925979	0	2925979	intron_variant	FALSE	0.295	9e-22	21.045757490560675	(Trans-ethnic initial)	0.0351	[0.028-0.042] unit decrease (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.295	NA	0.0351
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	19p13.2	19	11236817	ANGPTL8	DOCK6	NA	NA	ENSG00000130158	NA	NA	rs737337-T	rs737337	0	737337	synonymous_variant	FALSE	0.931	1e-21	21	(Trans-ethnic initial)	0.0565	[0.045-0.068] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.931	NA	0.0565
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	17q12	17	39657827	STARD3	STARD3	NA	NA	ENSG00000131748	NA	NA	rs1877031-A	rs1877031	0	1877031	missense_variant	FALSE	0.675	1e-21	21	(Trans-ethnic initial)	0.0336	[0.027-0.041] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.675	NA	0.0336
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	1p34.3	1	39370145	PABPC4	MACF1	NA	NA	ENSG00000127603	NA	NA	rs2296172-A	rs2296172	0	2296172	missense_variant	FALSE	0.806	2e-19	18.69897000433602	(Trans-ethnic initial)	0.0365	[0.028-0.045] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.806	NA	0.0365
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	2q36.3	2	226251649	IRS1	NYAP2 - MIR5702	ENSG00000144460	ENSG00000263363	NA	597631	407061	rs2972143-A	rs2972143	0	2972143	intergenic_variant	TRUE	0.373	2e-19	18.69897000433602	(Trans-ethnic initial)	0.0318	[0.025-0.039] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.373	NA	0.0318
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	8q23.3	8	115586972	TRPS1	TRPS1	NA	NA	ENSG00000104447	NA	NA	rs2293889-T	rs2293889	0	2293889	intron_variant	FALSE	0.413	5e-19	18.30102999566398	(Trans-ethnic initial)	0.0312	[0.024-0.038] unit decrease (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.413	NA	0.0312
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	7q32.2	7	130748625	KLF14	KLF14 - H4P1	ENSG00000266265	ENSG00000240680	NA	14418	74580	rs4731702-T	rs4731702	0	4731702	intergenic_variant	TRUE	0.46	1e-17	17	(Trans-ethnic initial)	0.0294	[0.023-0.036] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.46	NA	0.0294
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	12q24.31	12	123290580	SBNO1	SBNO1	NA	NA	ENSG00000139697	NA	NA	rs10773003-A	rs10773003	0	10773003	3_prime_UTR_variant	FALSE	0.0884	5e-17	16.30102999566398	(Trans-ethnic initial)	0.0431	[0.032-0.054] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.0884	NA	0.0431
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	8q24.13	8	125469835	TRIB1	TRIB1 - LINC00861	ENSG00000173334	ENSG00000245164	NA	31432	389886	rs2954021-A	rs2954021	0	2954021	intron_variant	TRUE	0.43	1e-8	8	(BMI unadjusted)	0.06	[0.04-0.08] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.43	NA	0.06
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	4q21.3	4	87084051	KLHL8	AFF1	NA	NA	ENSG00000172493	NA	NA	rs236996-A	rs236996	0	236996	intron_variant	FALSE	0.43	2e-8	7.698970004336019	(BMI adjusted)	0.0413	[0.026-0.057] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.43	NA	0.0413
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	15q21.3	15	58431476	LIPC	ALDH1A2, LIPC	NA	NA	ENSG00000128918, ENSG00000166035	NA	NA	rs1800588-T	rs1800588	0	1800588	intron_variant	FALSE	0.41	3e-6	5.522878745280337	(BMI unadjusted)	0.078	[0.045-0.111] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.41	NA	0.078
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	11q23.3	11	116768388	APOA1, APOC3, APOA4, APOA5	BUD13	NA	NA	ENSG00000137656	NA	NA	rs10790162-A	rs10790162	0	10790162	intron_variant	FALSE	0.22	2e-64	63.69897000433602	(BMI unadjusted)	0.214	[0.19-0.24] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.22	NA	0.214
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	12q24.11	12	110948323	MYL2	LINC01405	NA	NA	ENSG00000185847	NA	NA	rs2188380-T	rs2188380	0	2188380	intron_variant	FALSE	0.82	2e-8	7.698970004336019	(Asian initial, BMI adjusted)	0.061	[0.039-0.083] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.82	NA	0.061
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	1q42.13	1	230159169	GALNT2	GALNT2	NA	NA	ENSG00000143641	NA	NA	rs2144300-T	rs2144300	0	2144300	intron_variant	FALSE	0.18	5e-8	7.301029995663981	(Asian initial, BMI adjusted)	0.056	[0.036-0.076] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.18	NA	0.056
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	4q21.3	4	87061724	KLHL8	AFF1	NA	NA	ENSG00000172493	NA	NA	rs7660883-C	rs7660883	0	7660883	intron_variant	FALSE	0.58	6e-6	5.221848749616356	(Asian initial, BMI adjusted)	0.036	[0.02-0.052] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.58	NA	0.036
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	8p21.3	8	20028215	MET	LPL - RPL30P9	ENSG00000175445	ENSG00000242709	NA	60956	85128	rs11984636-T	rs11984636	0	11984636	intergenic_variant	TRUE	0.9	2e-26	25.69897000433602	(Asian initial, BMI unadjusted)	0.175	[0.14-0.21] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.9	NA	0.175
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	18q21.1	18	49592553	LIPG	LIPG	NA	NA	ENSG00000101670	NA	NA	rs3786247-T	rs3786247	0	3786247	3_prime_UTR_variant	FALSE	0.6	7e-19	18.154901959985743	(Asian initial, BMI unadjusted)	0.094	[0.074-0.114] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.6	NA	0.094
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	19q13.32	19	44919689	APOE, APOC1, APOC2	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855	NA	340	7115	rs4420638-A	rs4420638	0	4420638	regulatory_region_variant	TRUE	0.88	9e-17	16.045757490560675	(Asian initial, BMI unadjusted)	0.11	[0.085-0.135] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.88	NA	0.11
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	19p13.2	19	11235874	ANGPTL8	DOCK6	NA	NA	ENSG00000130158	NA	NA	rs3760782-T	rs3760782	0	3760782	intron_variant	FALSE	0.25	9e-11	10.045757490560675	(Asian initial, BMI unadjusted)	0.07	[0.048-0.092] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.25	NA	0.07
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	12q24.13	12	112379979	HECTD4	HECTD4	NA	NA	ENSG00000173064	NA	NA	rs11066280-A	rs11066280	0	11066280	intron_variant	FALSE	0.21	6e-10	9.221848749616356	(Asian initial, BMI unadjusted)	0.065	[0.043-0.087] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.21	NA	0.065
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	20q13.12	20	45952814	PLTP	ZNF335	NA	NA	ENSG00000198026	NA	NA	rs6124760-C	rs6124760	0	6124760	intron_variant	FALSE	0.94	2e-9	8.698970004336019	(Asian initial, BMI unadjusted)	0.104	[0.071-0.137] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.94	NA	0.104
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	16q22.1	16	67943479	LCAT	SLC12A4, LCAT	NA	NA	ENSG00000124067, ENSG00000213398	NA	NA	rs1109166-T	rs1109166	0	1109166	5_prime_UTR_variant	FALSE	0.87	3e-9	8.522878745280337	(Asian initial, BMI unadjusted)	0.071	[0.047-0.095] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.87	NA	0.071
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	12p13.31	12	7498542	CD163	CD163	NA	NA	ENSG00000177575	NA	NA	rs10743940-A	rs10743940	0	10743940	intron_variant	FALSE	0.3	7e-9	8.154901959985743	(Asian initial, BMI unadjusted)	0.05	[0.032-0.068] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.3	NA	0.05
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	7p21.1	7	17880630	SNX13	SNX13	NA	NA	ENSG00000071189	NA	NA	rs17138358-C	rs17138358	0	17138358	3_prime_UTR_variant	FALSE	0.53	2e-8	7.698970004336019	(Asian initial, BMI unadjusted)	0.043	[0.027-0.059] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.53	NA	0.043
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	22q11.21	22	21619030	UBE2L3	UBE2L3	NA	NA	ENSG00000185651	NA	NA	rs4821116-T	rs4821116	0	4821116	intron_variant	FALSE	0.39	4e-8	7.3979400086720375	(Asian initial, BMI unadjusted)	0.044	[0.028-0.06] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.39	NA	0.044
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237	NA	14548	2511	rs3764261-A	rs3764261	0	3764261	regulatory_region_variant	TRUE	0.169	2e-74	73.69897000433602	(Asian initial, BMI unadjusted)	0.262	[0.23-0.29] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.169	NA	0.262
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	11q23.3	11	116792991	APOA1, APOC3, APOA4, APOA5	APOA5 - APOA4	ENSG00000110243	ENSG00000110244	NA	571	27709	rs662799-A	rs662799	0	662799	intergenic_variant	TRUE	0.725	2e-71	70.69897000433602	(Asian initial, BMI unadjusted)	0.182	[0.16-0.2] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.725	NA	0.182
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	15q21.3	15	58431280	LIPC	LIPC, ALDH1A2	NA	NA	ENSG00000166035, ENSG00000128918	NA	NA	rs1077834-T	rs1077834	0	1077834	intron_variant	FALSE	0.586	2e-39	38.69897000433602	(Asian initial, BMI unadjusted)	0.133	[0.11-0.15] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.586	NA	0.133
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	8p21.3	8	19986711	LPL	LPL - NA	ENSG00000175445	NA	NA	19452	NA	rs12678919-A	rs12678919	0	12678919	intergenic_variant	TRUE	0.897	1e-36	36	(Asian initial, BMI unadjusted)	0.163	[0.14-0.19] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.897	NA	0.163
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	9q31.1	9	104902020	ABCA1	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs1883025-T	rs1883025	0	1883025	intron_variant	FALSE	0.246	7e-26	25.154901959985743	(Asian initial, BMI unadjusted)	0.0963	[0.078-0.114] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.246	NA	0.0963
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	12q24.31	12	123290580	SBNO1	SBNO1	NA	NA	ENSG00000139697	NA	NA	rs10773003-A	rs10773003	0	10773003	3_prime_UTR_variant	FALSE	0.296	6e-6	5.221848749616356	(Asian initial, BMI unadjusted)	0.0387	[0.022-0.056] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.296	NA	0.0387
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	15q21.3	15	58391167	LIPC	ALDH1A2	NA	NA	ENSG00000128918	NA	NA	rs1532085-A	rs1532085	0	1532085	intron_variant	FALSE	0.367	1e-213	213	(Trans-ethnic initial)	0.107	[0.1-0.11] unit increase (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.367	NA	0.107
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	HDL cholesterol levels	34,930 East Asian ancestry individuals, 187,167 European ancestry individuals	8,741 Chinese ancestry individuals	8p21.3	8	19986711	LPL	LPL - NA	ENSG00000175445	NA	NA	19452	NA	rs12678919-A	rs12678919	0	12678919	intergenic_variant	TRUE	0.879	4e-176	175.39794000867204	(Trans-ethnic initial)	0.155	[0.14-0.17] unit decrease (EA Beta values)	Affymetrix, Illumina [~ 1900000] (imputed)	N	high density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004612	GCST004232	Genome-wide genotyping array	0.879	NA	0.155
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	22q13.1	22	38199404	PLA2G6	PLA2G6	NA	NA	ENSG00000184381	NA	NA	rs3761445-A	rs3761445	0	3761445	intron_variant	FALSE	0.615	3e-12	11.522878745280337	(Trans-ethnic initial)	0.0232	[0.017-0.03] unit increase (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.615	NA	0.0232
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	8p23.1	8	10813750	PINX1	PINX1, PINX1, PINX1	NA	NA	ENSG00000284764, ENSG00000254093, ENSG00000258724	NA	NA	rs6995541-A	rs6995541	0	6995541	intron_variant	FALSE	0.678	3e-12	11.522878745280337	(Trans-ethnic initial)	0.0265	[0.019-0.034] unit decrease (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.678	NA	0.0265
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	10q23.33	10	93079885	CYP26A1	CYP26A1 - NIP7P1	ENSG00000095596	ENSG00000232805	NA	2000	26987	rs2068888-A	rs2068888	0	2068888	regulatory_region_variant	TRUE	0.491	3e-12	11.522878745280337	(Trans-ethnic initial)	0.0241	[0.017-0.031] unit decrease (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.491	NA	0.0241
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	12q24.31	12	123980289	ZNF664	ZNF664, RFLNA	NA	NA	ENSG00000179195, ENSG00000178882	NA	NA	rs11057408-T	rs11057408	0	11057408	intron_variant	FALSE	0.363	2e-11	10.698970004336019	(Trans-ethnic initial)	0.0258	[0.019-0.033] unit decrease (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.363	NA	0.0258
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	19q13.32	19	44892962	APOE, APOC1, APOC2	TOMM40	NA	NA	ENSG00000130204	NA	NA	rs157582-T	rs157582	0	157582	intron_variant	FALSE	0.19	2e-10	9.698970004336019	(Asian initial, BMI unadjusted)	0.108	[0.075-0.141] unit increase	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.19	NA	0.108
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	19p13.2	19	7224420	INSR	INSR	NA	NA	ENSG00000171105	NA	NA	rs7248104-A	rs7248104	0	7248104	intron_variant	FALSE	0.417	6e-10	9.221848749616356	(Trans-ethnic initial)	0.0222	[0.016-0.029] unit decrease (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.417	NA	0.0222
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	1p36.11	1	26811902	PIGV, NROB2	PIGV - RN7SL165P	ENSG00000060642	ENSG00000241188	NA	11243	2920	rs12748152-T	rs12748152	0	12748152	regulatory_region_variant	TRUE	0.0712	1e-9	9	(Trans-ethnic initial)	0.0372	[0.026-0.049] unit increase (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.0712	NA	0.0372
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	19q13.11	19	33408159	PEPD	PEPD	NA	NA	ENSG00000124299	NA	NA	rs731839-A	rs731839	0	731839	intron_variant	FALSE	0.658	3e-9	8.522878745280337	(Trans-ethnic initial)	0.0224	[0.015-0.029] unit decrease (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.658	NA	0.0224
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	7q31.2	7	116717990	MET	MET	NA	NA	ENSG00000105976	NA	NA	rs38855-A	rs38855	0	38855	intron_variant	FALSE	0.526	5e-9	8.301029995663981	(Trans-ethnic initial)	0.0187	[0.012-0.025] unit increase (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.526	NA	0.0187
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	16p13.11	16	15036113	PDXDC1	PDXDC1	NA	NA	ENSG00000179889	NA	NA	rs7200543-A	rs7200543	0	7200543	synonymous_variant	FALSE	0.681	6e-9	8.221848749616356	(Trans-ethnic initial)	0.021	[0.014-0.028] unit decrease (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.681	NA	0.021
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	16p11.2	16	31106092	CTF1	VKORC1 - BCKDK	ENSG00000167397	ENSG00000103507	NA	10112	15	rs2032915-T	rs2032915	0	2032915	regulatory_region_variant	TRUE	0.396	9e-9	8.045757490560675	(Trans-ethnic initial)	0.0211	[0.014-0.028] unit decrease (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.396	NA	0.0211
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	6q22.33	6	127093656	RSPO3	NA - RSPO3	NA	ENSG00000146374	NA	NA	25015	rs719726-T	rs719726	0	719726	non_coding_transcript_exon_variant	TRUE	0.529	1e-8	8	(Trans-ethnic initial)	0.0199	[0.013-0.027] unit increase (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.529	NA	0.0199
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	15q15.3	15	43953733	FRMD5	FRMD5	NA	NA	ENSG00000171877	NA	NA	rs2929282-A	rs2929282	0	2929282	intron_variant	FALSE	0.0	2e-8	7.698970004336019	(Trans-ethnic initial)	0.0725	[0.049-0.096] unit decrease (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0	NA	0.0725
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	7q11.23	7	73353442	TYW1B	FKBP6	NA	NA	ENSG00000077800	NA	NA	rs1178968-T	rs1178968	0	1178968	intron_variant	FALSE	0.124	2e-8	7.698970004336019	(Trans-ethnic initial)	0.0282	[0.019-0.037] unit decrease (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.124	NA	0.0282
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	13q32.1	13	94632726	GPR180	GPR180	NA	NA	ENSG00000152749	NA	NA	rs1341267-A	rs1341267	0	1341267	3_prime_UTR_variant	FALSE	0.4222	3e-8	7.522878745280337	(Trans-ethnic initial)	0.0184	[0.012-0.025] unit increase (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.4222	NA	0.0184
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	16q12.2	16	53766065	FTO	FTO	NA	NA	ENSG00000140718	NA	NA	rs9930333-T	rs9930333	0	9930333	intron_variant	FALSE	0.551	8e-8	7.096910013008056	(Trans-ethnic initial)	0.0208	[0.014-0.028] unit decrease (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.551	NA	0.0208
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	12q23.3	12	106780868	RFX4, RIC8B	RIC8B	NA	NA	ENSG00000111785	NA	NA	rs10861661-A	rs10861661	0	10861661	intron_variant	FALSE	0.2375	2e-7	6.698970004336019	(Trans-ethnic initial)	0.0227	[0.015-0.031] unit increase (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	0.2375	NA	0.0227
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	28,183 East Asian ancestry individuals, 177,861 European ancestry individuals	10,857 Chinese ancestry individuals	15q24.1	15	72796528	ADPGK	ADPGK-AS1	NA	NA	ENSG00000260898	NA	NA	rs8027181-A	rs8027181	0	8027181	intron_variant	FALSE	1.0	3e-7	6.522878745280337	(Trans-ethnic initial)	0.0242	[0.014-0.034] unit increase (EA Beta values)	Affymetrix, Illumina [up to 1900000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004237	Genome-wide genotyping array	1	NA	0.0242
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	2p23.3	2	27520348	GCKR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs814295-A	rs814295	0	814295	intron_variant	FALSE	0.67	5e-20	19.30102999566398	(BMI unadjusted)	0.102	[0.08-0.124] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.67	NA	0.102
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	NA	NA	NA	LPL	NA	NA	NA	NA	NA	NA	rs10503669-A	rs10503669	0	10503669	intergenic_variant	TRUE	0.11	1e-19	19	(BMI unadjusted)	0.16	[0.13-0.19] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.11	NA	0.16
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	8p21.3	8	20028215	MET	LPL - RPL30P9	ENSG00000175445	ENSG00000242709	NA	60956	85128	rs11984636-T	rs11984636	0	11984636	intergenic_variant	TRUE	0.89	3e-18	17.522878745280337	(BMI unadjusted)	0.165	[0.13-0.2] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.89	NA	0.165
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	7q11.23	7	73442719	MLXIPL	BAZ1B	NA	NA	ENSG00000009954	NA	NA	rs1178977-A	rs1178977	0	1178977	splice_region_variant	FALSE	0.89	1e-11	11	(BMI unadjusted)	0.122	[0.087-0.157] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.89	NA	0.122
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	1p31.3	1	62641855	ANGPTL3	DOCK7	NA	NA	ENSG00000116641	NA	NA	rs995000-T	rs995000	0	995000	intron_variant	FALSE	0.18	2e-10	9.698970004336019	(BMI unadjusted)	0.085	[0.06-0.11] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.18	NA	0.085
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	22q13.1	22	38551830	PLA2G6	DMC1	NA	NA	ENSG00000100206	NA	NA	rs5757133-T	rs5757133	0	5757133	intron_variant	FALSE	0.38	4e-10	9.397940008672037	(BMI adjusted)	0.0363	[0.024-0.049] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.38	NA	0.0363
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Triglyceride levels	18,421 East Asian ancestry individuals	38,060 East Asian ancestry individuals	20q13.12	20	45948343	PLTP	PCIF1 - ZNF335	ENSG00000100982	ENSG00000198026	NA	320	317	rs6130975-A	rs6130975	0	6130975	regulatory_region_variant	TRUE	0.06	6e-10	9.221848749616356	(BMI adjusted)	0.097	[0.066-0.128] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	triglyceride measurement	http://www.ebi.ac.uk/efo/EFO_0004530	GCST004238	Genome-wide genotyping array	0.06	NA	0.097
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.32	1;1	3705742;3703616	NR	TP73; TP73	NA	NA	NA	NA	NA	rs3765753-G; rs17379833-A	rs3765753; rs17379833	0	NA	intron_variant; intron_variant	NA	0.334	5e-13	12.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.334	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.32	1;1	3705742;3703616	NR	TP73; TP73	NA	NA	NA	NA	NA	rs3765753-T; rs17379833-A	rs3765753; rs17379833	0	NA	intron_variant; intron_variant	NA	0.28	5e-13	12.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.28	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.32	1	4308381	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs351622-T; rs3912751-C; rs351596-T; rs3912752-T; rs12408318-T; rs1495237-T; rs351614-C; rs12744254-A; rs351615-A; rs351619-G; rs12132314-C	rs351622; rs3912751; rs351596; rs3912752; rs12408318; rs1495237; rs351614; rs12744254; rs351615; rs351619; rs12132314	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	5e-16	15.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.32	1	4308381	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs351622-T; rs3912751-T; rs351596-T; rs3912752-T; rs12408318-T; rs1495237-T; rs351614-C; rs12744254-A; rs351615-A; rs351619-G; rs12132314-C	rs351622; rs3912751; rs351596; rs3912752; rs12408318; rs1495237; rs351614; rs12744254; rs351615; rs351619; rs12132314	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.201	4e-10	9.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.201	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.32	1	4634538	NR	LINC01646 - AJAP1; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12405615-T; rs12744374-C; rs6687814-A; rs2071967-C	rs12405615; rs12744374; rs6687814; rs2071967	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.121	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.121	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.32	1	5090400	NR	LINC02782; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12723011-A; rs10915342-T; rs2199215-T; rs6680801-G; rs12120144-G; rs12405346-C; rs10915343-T; rs12121092-G; rs1459766-G; rs3101225-A	rs12723011; rs10915342; rs2199215; rs6680801; rs12120144; rs12405346; rs10915343; rs12121092; rs1459766; rs3101225	0	NA	intron_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intron_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.012	6e-18	17.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.012	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.32	1	5090400	NR	LINC02782; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs12723011-A; rs10915342-T; rs2199215-T; rs6680801-G; rs12120144-G; rs12405346-C; rs10915343-T; rs12121092-G; rs1459766-T; rs3101225-A	rs12723011; rs10915342; rs2199215; rs6680801; rs12120144; rs12405346; rs10915343; rs12121092; rs1459766; rs3101225	0	NA	intron_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intron_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.257	5e-10	9.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.257	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.22	1	9232023	NR	MIR34AHG - H6PD; No mapped genes	NA	NA	NA	NA	NA	rs3753271-T; rs2157479-A	rs3753271; rs2157479	0	NA	intergenic_variant; intergenic_variant	NA	0.0	8e-6	5.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.22	1	9365481	NR	SPSB1; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10864411-C; rs9660866-C; rs11121390-G; rs2275458-G	rs10864411; rs9660866; rs11121390; rs2275458	0	NA	intron_variant; intergenic_variant; 3_prime_UTR_variant; 3_prime_UTR_variant	NA	0.423	1e-22	22	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.423	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.22	1	9365481	NR	SPSB1; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10864411-C; rs9660866-C; rs11121390-G; rs2275458-A	rs10864411; rs9660866; rs11121390; rs2275458	0	NA	intron_variant; intergenic_variant; 3_prime_UTR_variant; 3_prime_UTR_variant	NA	0.17	5e-18	17.30102999566398	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.17	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.22	1	10763729	NR	CASZ1; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs6540948-A; rs11121613-G; rs17035686-C; rs205488-C; rs17035680-T	rs6540948; rs11121613; rs17035686; rs205488; rs17035680	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.71	8e-6	5.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.71	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.13	1;1	17640549;17692362	NR	ARHGEF10L; No mapped genes; No mapped genes; ARHGEF10L; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11800478-C; rs6657353-A; rs6665721-C; rs12143113-C; rs3766309-T; rs1109875-T; rs6703771-T; rs12565468-C; rs11580813-G; rs2134482-G; rs7528550-A; rs7531556-T; rs12067869-T; rs869526-G; rs17469160-G	rs11800478; rs6657353; rs6665721; rs12143113; rs3766309; rs1109875; rs6703771; rs12565468; rs11580813; rs2134482; rs7528550; rs7531556; rs12067869; rs869526; rs17469160	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.005	1e-13	13	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.005	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.13	1;1	17640549;17692362	NR	ARHGEF10L; No mapped genes; No mapped genes; ARHGEF10L; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11800478-C; rs6657353-A; rs6665721-C; rs12143113-T; rs3766309-T; rs1109875-T; rs6703771-T; rs12565468-C; rs11580813-G; rs2134482-G; rs7528550-A; rs7531556-T; rs12067869-T; rs869526-G; rs17469160-G	rs11800478; rs6657353; rs6665721; rs12143113; rs3766309; rs1109875; rs6703771; rs12565468; rs11580813; rs2134482; rs7528550; rs7531556; rs12067869; rs869526; rs17469160	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.155	1e-7	7	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.155	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.13	1	17836417	NR	ACTL8 - N/A; No mapped genes	NA	NA	NA	NA	NA	rs11203475-A; rs495347-C	rs11203475; rs495347	0	NA	intergenic_variant; intergenic_variant	NA	0.021	7e-6	5.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.021	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.13	1	18196837	NR	IGSF21; No mapped genes	NA	NA	NA	NA	NA	rs4920453-G; rs12046227-G	rs4920453; rs12046227	0	NA	intron_variant; intron_variant	NA	0.338	8e-16	15.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.338	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.13	1	18196837	NR	IGSF21; No mapped genes	NA	NA	NA	NA	NA	rs4920453-T; rs12046227-G	rs4920453; rs12046227	0	NA	intron_variant; intron_variant	NA	0.302	3e-11	10.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.302	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.13	1	18362758	NR	IGSF21; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4920485-A; rs1763903-T; rs2003724-A; rs10489573-C; rs4920486-C	rs4920485; rs1763903; rs2003724; rs10489573; rs4920486	0	NA	intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant	NA	0.01	8e-9	8.096910013008056	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.01	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.13	1	20084302	NR	PLA2G5; No mapped genes	NA	NA	NA	NA	NA	rs660414-G; rs2020887-C	rs660414; rs2020887	0	NA	intron_variant; synonymous_variant	NA	0.18	2e-8	7.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.18	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.11	1	25660031	NR	MAN1C1; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2982309-C; rs3014715-G; rs876765-C; rs2982313-A	rs2982309; rs3014715; rs876765; rs2982313	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.002	3e-6	5.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.002	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.11	1;1	26456189;26542148	NR	DHDDS; No mapped genes; No mapped genes; RPS6KA1; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs3127011-G; rs12094989-C; rs12723046-G; rs6685701-G; rs1982525-C; rs11576300-G; rs4659444-C; rs6670311-C	rs3127011; rs12094989; rs12723046; rs6685701; rs1982525; rs11576300; rs4659444; rs6670311	0	NA	intron_variant; regulatory_region_variant; non_coding_transcript_exon_variant; intron_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; intron_variant	NA	0.063	6e-18	17.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.063	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p36.11	1;1	26456189;26542148	NR	DHDDS; No mapped genes; No mapped genes; RPS6KA1; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs3127011-G; rs12094989-C; rs12723046-G; rs6685701-A; rs1982525-C; rs11576300-G; rs4659444-C; rs6670311-C	rs3127011; rs12094989; rs12723046; rs6685701; rs1982525; rs11576300; rs4659444; rs6670311	0	NA	intron_variant; regulatory_region_variant; non_coding_transcript_exon_variant; intron_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; intron_variant	NA	0.237	1e-10	10	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.237	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p35.3	1	29876357	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1448338-T; rs4949507-C; rs7547546-G; rs12037930-A; rs7552039-G; rs10798906-C; rs7513406-T; rs7538432-C; rs4949505-A; rs4949506-G; rs1448337-C; rs4949225-C; rs12032770-C	rs1448338; rs4949507; rs7547546; rs12037930; rs7552039; rs10798906; rs7513406; rs7538432; rs4949505; rs4949506; rs1448337; rs4949225; rs12032770	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.0	1e-30	30	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p35.3	1	29876357	NR	No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1448338-T; rs4949507-A; rs7547546-G; rs12037930-A; rs7552039-G; rs10798906-C; rs7513406-T; rs7538432-C; rs4949505-A; rs4949506-G; rs1448337-C; rs4949225-C; rs12032770-C	rs1448338; rs4949507; rs7547546; rs12037930; rs7552039; rs10798906; rs7513406; rs7538432; rs4949505; rs4949506; rs1448337; rs4949225; rs12032770	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.354	6e-20	19.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.354	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p35.2	1	29937655	NR	N/A - LINC01648; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4949232-A; rs16833076-T; rs10798928-T; rs1498243-G; rs4245639-G	rs4949232; rs16833076; rs10798928; rs1498243; rs4245639	0	NA	intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant	NA	0.004	2e-16	15.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.004	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p35.2	1	29937655	NR	N/A - LINC01648; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs4949232-A; rs16833076-T; rs10798928-C; rs1498243-G; rs4245639-G	rs4949232; rs16833076; rs10798928; rs1498243; rs4245639	0	NA	intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant	NA	0.2	6e-10	9.221848749616356	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.2	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1p34.1	1	46047340	PIK3R3, RP4-533D7.4	PIK3R3, P3R3URF-PIK3R3	NA	NA	ENSG00000117461, ENSG00000278139	NA	NA	rs1612092-C	rs1612092	0	1612092	intron_variant	FALSE	0.4354	1e-10	10	NA	0.02333103	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4354	NA	0.02333103
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1p31.3	1	65445924	LEPR	LEPR	NA	NA	ENSG00000116678	NA	NA	rs9436747-C	rs9436747	0	9436747	intron_variant	FALSE	0.6285	2e-16	15.698970004336019	NA	0.03050646	[0.023-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.6285	NA	0.03050646
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1p31.3	1	65671509	intergenic	LEPR - RN7SL854P	ENSG00000116678	ENSG00000239319	NA	29950	89549	rs34293785-C	rs34293785	0	34293785	intergenic_variant	TRUE	0.3663	1e-34	34	NA	0.0458313	[0.039-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3663	NA	0.0458313
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1p13.3	1	108200437	SLC25A24	SLC25A24	NA	NA	ENSG00000284468	NA	NA	rs663045-C	rs663045	0	663045	5_prime_UTR_variant	FALSE	0.5335	6e-10	9.221848749616356	NA	0.02226758	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5335	NA	0.02226758
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1p13.3	1	109928142	CSF1	CSF1	NA	NA	ENSG00000184371	NA	NA	rs333947-A	rs333947	0	333947	intron_variant	FALSE	0.1505	3e-9	8.522878745280337	NA	0.02965985	[0.02-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1505	NA	0.02965985
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1p13.2	1	113834946	PTPN22	PTPN22	NA	NA	ENSG00000134242	NA	NA	rs2476601-G	rs2476601	0	2476601	missense_variant	FALSE	0.8983	2e-21	20.69897000433602	NA	0.05610971	[0.045-0.068] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.8983	NA	0.05610971
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1q23.2	1	159205704	DARC	ACKR1, CADM3-AS1	NA	NA	ENSG00000213088, ENSG00000225670	NA	NA	rs34599082-T	rs34599082	0	34599082	missense_variant	FALSE	0.0138	3e-23	22.522878745280337	NA	0.1527298	[0.12-0.18] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0138	NA	0.1527298
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1q23.2	1	159313100	FCER1A, OR10J3	FCER1A - OR10J3	ENSG00000179639	ENSG00000196266	NA	4876	620	rs565021665-C	rs565021665	1	36034366	intergenic_variant	TRUE	0.5056	4e-13	12.397940008672037	NA	0.02653775	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5056	NA	0.02653775
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1q23.2	1	159549102	intergenic	OR10J5 - OR10AE1P	ENSG00000184155	ENSG00000271890	NA	13095	32518	rs2369135-A	rs2369135	0	2369135	intergenic_variant	TRUE	0.9983	2e-9	8.698970004336019	NA	0.2950005	[0.2-0.39] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.9983	NA	0.2950005
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1q32.2	1	207860984	C1orf132	MIR29B2CHG	NA	NA	ENSG00000203709	NA	NA	rs4844622-T	rs4844622	0	4844622	intron_variant	FALSE	0.2411	7e-10	9.154901959985743	NA	0.02585704	[0.018-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2411	NA	0.02585704
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1q42.11	1	224394506	WDR26	WDR26	NA	NA	ENSG00000162923	NA	NA	rs34687215-C	rs34687215	0	34687215	intron_variant	FALSE	0.2351	4e-9	8.397940008672037	NA	0.02575367	[0.017-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2351	NA	0.02575367
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1q42.3	1	235926855	intergenic	RNU6-968P - LINC02768	ENSG00000206803	ENSG00000229291	NA	11334	31024	rs2208568-C	rs2208568	0	2208568	intergenic_variant	TRUE	0.892	6e-31	30.221848749616356	NA	0.06737916	[0.056-0.079] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.892	NA	0.06737916
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1q44	1	247438293	NLRP3	NLRP3	NA	NA	ENSG00000162711	NA	NA	rs12239046-C	rs12239046	0	12239046	intron_variant	FALSE	0.6282	6e-18	17.221848749616356	NA	0.03195252	[0.025-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.6282	NA	0.03195252
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	1q44	1	247876149	TRIM58	TRIM58	NA	NA	ENSG00000162722	NA	NA	rs3811444-T	rs3811444	0	3811444	missense_variant	FALSE	0.3359	2e-9	8.698970004336019	NA	0.02284256	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3359	NA	0.02284256
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2p24.1	2	23784252	ATAD2B	ATAD2B	NA	NA	ENSG00000119778	NA	NA	rs72780191-C	rs72780191	0	72780191	intron_variant	FALSE	0.1309	2e-19	18.69897000433602	NA	0.0477607	[0.037-0.058] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1309	NA	0.0477607
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2p23.3	2	27508073	GCKR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs1260326-C	rs1260326	0	1260326	missense_variant	FALSE	0.6053	9e-21	20.045757490560675	NA	0.03410984	[0.027-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.6053	NA	0.03410984
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2p16.1	2	54766861	EML6	EML6	NA	NA	ENSG00000214595	NA	NA	rs17046310-T	rs17046310	0	17046310	intron_variant	FALSE	0.0326	3e-9	8.522878745280337	NA	0.05966194	[0.04-0.079] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0326	NA	0.05966194
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2p15	2	61476184	RP11-355B11.2	XPO1, USP34-DT	NA	NA	ENSG00000082898, ENSG00000270820	NA	NA	rs10206089-A	rs10206089	0	10206089	non_coding_transcript_exon_variant	FALSE	0.3775	7e-11	10.154901959985743	NA	0.02595066	[0.018-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3775	NA	0.02595066
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2p14	2	65419832	SPRED2	SPRED2	NA	NA	ENSG00000198369	NA	NA	rs7565437-C	rs7565437	0	7565437	intron_variant	FALSE	0.4086	8e-9	8.096910013008056	NA	0.02110318	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4086	NA	0.02110318
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q14.1	2	113083453	RNU6-1180P	IL1F10 - RNU6-1180P	ENSG00000136697	ENSG00000201805	NA	7610	3352	rs6734238-G	rs6734238	0	6734238	regulatory_region_variant	TRUE	0.4034	1e-17	17	NA	0.03115854	[0.024-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4034	NA	0.03115854
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q22.2	2	143129250	ARHGAP15	ARHGAP15	NA	NA	ENSG00000075884	NA	NA	rs79716587-A	rs79716587	0	79716587	intron_variant	FALSE	0.1275	2e-13	12.698970004336019	NA	0.03991238	[0.029-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1275	NA	0.03991238
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q24.2	2	160479895	RBMS1	RBMS1	NA	NA	ENSG00000153250	NA	NA	rs10178094-A	rs10178094	0	10178094	intron_variant	FALSE	0.4675	4e-9	8.397940008672037	NA	0.02114093	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4675	NA	0.02114093
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q24.3	2	168850753	NOSTRIN, SPC25	NOSTRIN, NOSTRIN, SPC25, SPC25	NA	NA	ENSG00000275326, ENSG00000163072, ENSG00000152253, ENSG00000277909	NA	NA	rs139707092-A	rs139707092	1	5836209	intron_variant	FALSE	0.3194	5e-16	15.301029995663981	NA	0.03124008	[0.024-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3194	NA	0.03124008
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q31.3	2	181042998	UBE2E3	UBE2E3	NA	NA	ENSG00000170035	NA	NA	rs6745190-G	rs6745190	0	6745190	intron_variant	FALSE	0.2755	8e-11	10.096910013008056	NA	0.02629854	[0.018-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2755	NA	0.02629854
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q31.3	2	181443625	intergenic	LINC01934 - ITGA4	ENSG00000234663	ENSG00000115232	NA	34304	13577	rs6740847-G	rs6740847	0	6740847	intergenic_variant	TRUE	0.5634	4e-25	24.397940008672037	NA	0.03747913	[0.03-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5634	NA	0.03747913
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q35	2	218135259	CXCR2	CXCR2	NA	NA	ENSG00000180871	NA	NA	rs55799208-A	rs55799208	0	55799208	missense_variant	FALSE	0.0029	6e-32	31.221848749616356	NA	0.4224498	[0.35-0.49] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0029	NA	0.4224498
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q35	2	218156235	intergenic	CXCR2 - CXCR1	ENSG00000180871	ENSG00000163464	NA	18984	6606	rs114050631-T	rs114050631	0	114050631	regulatory_region_variant	TRUE	0.0107	4e-13	12.397940008672037	NA	0.1411712	[0.1-0.18] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.0107	NA	0.1411712
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q35	2	218297999	PNKD	PNKD	NA	NA	ENSG00000127838	NA	NA	rs145013566-CA	rs145013566	0	145013566	intron_variant	FALSE	0.5243	2e-10	9.698970004336019	NA	0.02352016	[0.016-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.5243	NA	0.02352016
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q37.1	2	231714669	PTMA	PTMA - PDE6D	ENSG00000187514	ENSG00000156973	NA	1118	17764	rs58106596-A	rs58106596	0	58106596	regulatory_region_variant	TRUE	0.2227	3e-9	8.522878745280337	NA	0.02582399	[0.017-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2227	NA	0.02582399
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	2q37.3	2	236867522	intergenic	NA	NA	NA	NA	NA	NA	rs9287604-C	rs9287604	0	9287604	intergenic_variant	TRUE	0.7325	1e-12	12	NA	0.02912524	[0.021-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.7325	NA	0.02912524
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	3p25.2	3	12225304	intergenic	SYN2 - GSTM5P1	ENSG00000157152	ENSG00000236062	NA	33272	32497	rs1822534-G	rs1822534	0	1822534	intergenic_variant	TRUE	0.394	1e-12	12	NA	0.02614186	[0.019-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.394	NA	0.02614186
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	3p22.1	3	42836219	KRBOX1, ACKR2, RP11-141M3.5, RP11-70C1.3	KRBOX1, ACKR2	NA	NA	ENSG00000240747, ENSG00000144648	NA	NA	rs4682863-G	rs4682863	0	4682863	intron_variant	FALSE	0.4098	2e-14	13.698970004336019	NA	0.02792974	[0.021-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4098	NA	0.02792974
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	3p21.31	3	47046347	SETD2	SETD2	NA	NA	ENSG00000181555	NA	NA	rs13063578-A	rs13063578	0	13063578	intron_variant	FALSE	0.4018	3e-19	18.522878745280337	NA	0.032872	[0.026-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4018	NA	0.032872
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	3q21.3	3	128603031	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	26945	16938	rs11359909-A	rs11359909	0	11359909	intergenic_variant	TRUE	0.8935	1e-13	13	NA	0.04348204	[0.032-0.055] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.8935	NA	0.04348204
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	3q21.3	3	128604581	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	28495	15388	rs6782228-C	rs6782228	0	6782228	intergenic_variant	TRUE	0.2679	1e-14	14	NA	0.03151812	[0.024-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2679	NA	0.03151812
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	3q23	3	141208279	intergenic	SPSB4 - PXYLP1	ENSG00000175093	ENSG00000155893	NA	59668	20447	rs143699489-G	rs143699489	0	143699489	intergenic_variant	TRUE	0.1268	1e-9	9	NA	0.03292191	[0.022-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1268	NA	0.03292191
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	3q23	3	141487958	RASA2	RASA2	NA	NA	ENSG00000155903	NA	NA	rs9819371-T	rs9819371	0	9819371	intron_variant	FALSE	0.065	9e-10	9.045757490560675	NA	0.04457167	[0.03-0.059] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.065	NA	0.04457167
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	3q29	3	196762551	PAK2	PAK2	NA	NA	ENSG00000180370	NA	NA	rs13434265-T	rs13434265	0	13434265	intron_variant	FALSE	0.416	9e-17	16.045757490560675	NA	0.0303966	[0.023-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.416	NA	0.0303966
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	4p16.3	4	709183	PCGF3	PCGF3	NA	NA	ENSG00000185619	NA	NA	rs56011263-C	rs56011263	0	56011263	intron_variant	FALSE	0.3866	5e-9	8.301029995663981	NA	0.02156262	[0.014-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3866	NA	0.02156262
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	4p14	4	38675391	KLF3	KLF3	NA	NA	ENSG00000109787	NA	NA	rs552599526-TC	rs552599526	1	11429183	intron_variant	FALSE	0.4475	2e-13	12.698970004336019	NA	0.02660141	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4475	NA	0.02660141
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	4q12	4	54542832	intergenic	LINC02283 - LINC02260	ENSG00000248184	ENSG00000250456	NA	186878	60379	rs218265-C	rs218265	0	218265	intergenic_variant	TRUE	0.1571	2e-13	12.698970004336019	NA	0.03676361	[0.027-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1571	NA	0.03676361
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	4q12	4	54632615	intergenic	LINC02260 - KIT	ENSG00000250456	ENSG00000157404	NA	25484	25303	rs35484700-C	rs35484700	0	35484700	intergenic_variant	TRUE	0.4876	1e-9	9	NA	0.02166894	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4876	NA	0.02166894
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	4q13.3	4	71749645	GC	GC	NA	NA	ENSG00000145321	NA	NA	rs11723621-G	rs11723621	0	11723621	intron_variant	FALSE	0.2918	2e-11	10.698970004336019	NA	0.02635404	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.2918	NA	0.02635404
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	4q13.3	4	73838282	CXCL6	CXCL6	NA	NA	ENSG00000124875	NA	NA	rs16850073-T	rs16850073	0	16850073	3_prime_UTR_variant	FALSE	0.375	3e-34	33.52287874528034	NA	0.04534241	[0.038-0.053] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.375	NA	0.04534241
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	4q13.3	4	74094279	CXCL2	PPBPP2 - CXCL2	ENSG00000248848	ENSG00000081041	NA	38880	2761	rs11725704-G	rs11725704	0	11725704	regulatory_region_variant	TRUE	0.3765	2e-71	70.69897000433602	NA	0.06609053	[0.059-0.073] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.3765	NA	0.06609053
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	4q21.22	4	82624823	LINC00575	LINC00575 - SCD5	ENSG00000231782	ENSG00000145284	NA	3213	4716	rs13138355-T	rs13138355	0	13138355	regulatory_region_variant	TRUE	0.1862	6e-20	19.221848749616356	NA	0.04207902	[0.033-0.051] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.1862	NA	0.04207902
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	4q31.21	4	144168712	intergenic	GYPA - NA	ENSG00000170180	NA	NA	27961	NA	rs34257361-A	rs34257361	0	34257361	intron_variant	TRUE	0.4739	1e-10	10	NA	0.02358875	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4739	NA	0.02358875
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	5p15.33	5	1285859	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs7705526-A	rs7705526	0	7705526	intron_variant	FALSE	0.329	8e-18	17.096910013008056	NA	0.03350265	[0.026-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.329	NA	0.03350265
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	5q13.2	5	69297096	CCDC125	CCDC125, CCDC125	NA	NA	ENSG00000277868, ENSG00000183323	NA	NA	rs72767881-T	rs72767881	0	72767881	intron_variant	FALSE	0.4443	3e-12	11.522878745280337	NA	0.02512704	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.4443	NA	0.02512704
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count	172,435 European ancestry individuals	NA	5q13.2	5	72432861	intergenic	YBX1P5 - ZNF366	ENSG00000251108	ENSG00000178175	NA	14526	7042	rs2338224-G	rs2338224	0	2338224	intergenic_variant	TRUE	0.8788	1e-11	11	NA	0.03733984	[0.027-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	leukocyte count	http://www.ebi.ac.uk/efo/EFO_0004308	GCST004610	Genome-wide genotyping array	0.8788	NA	0.03733984
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p24.1	3	27521497	NR	RNU1-96P - Y_RNA	ENSG00000201033	ENSG00000199964	NA	7465	26260	rs2643826-C	rs2643826	0	2643826	regulatory_region_variant	TRUE	NA	2e-6	5.698970004336019	NA	0.176	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	17q23.1	17	59775853	VMP1	VMP1	NA	NA	ENSG00000062716	NA	NA	rs2645466-A	rs2645466	0	2645466	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.18	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q21.33	12	89619312	ATP2B1	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs2681492-T	rs2681492	0	2681492	intron_variant	FALSE	NA	2e-8	7.698970004336019	(EA)	0.296	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q21.33	12	89619312	ATP2B1	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs2681492-T	rs2681492	0	2681492	intron_variant	FALSE	NA	4e-9	8.397940008672037	NA	0.275	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q24.3	2	164097664	NR	FIGN - PRPS1P1	ENSG00000182263	ENSG00000226847	NA	361652	115875	rs268263-T	rs268263	0	268263	intron_variant	TRUE	NA	1e-6	6	(EA)	0.222	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q24.3	2	164097664	NR	FIGN - PRPS1P1	ENSG00000182263	ENSG00000226847	NA	361652	115875	rs268263-T	rs268263	0	268263	intron_variant	TRUE	NA	1e-7	7	(East Asian)	0.738	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q24.3	2	164097664	NR	FIGN - PRPS1P1	ENSG00000182263	ENSG00000226847	NA	361652	115875	rs268263-T	rs268263	0	268263	intron_variant	TRUE	NA	1e-11	11	NA	0.276	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q31.2	2	177227434	MIR4444-1, MIR3128	HNRNPA3 - NFE2L2	ENSG00000170144	ENSG00000116044	NA	3476	161	rs2706110-T	rs2706110	0	2706110	regulatory_region_variant	TRUE	NA	2e-6	5.698970004336019	NA	0.212	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1q32.2	1	207746403	CR1L, CD46	CR1L - CD46	ENSG00000197721	ENSG00000117335	NA	7987	5651	rs2761436-C	rs2761436	0	2761436	regulatory_region_variant	TRUE	NA	6e-8	7.221848749616356	(EA)	0.219	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1q32.2	1	207746403	CR1L, CD46	CR1L - CD46	ENSG00000197721	ENSG00000117335	NA	7987	5651	rs2761436-C	rs2761436	0	2761436	regulatory_region_variant	TRUE	NA	3e-7	6.522878745280337	NA	0.188	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	15q21.2	15	50646781	TRPM7	TRPM7	NA	NA	ENSG00000092439	NA	NA	rs2899463-T	rs2899463	0	2899463	intron_variant	FALSE	NA	3e-6	5.522878745280337	NA	0.167	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q23.1	5	121951366	FTMT, SRFBP1	FTMT - SRFBP1	ENSG00000181867	ENSG00000151304	NA	98533	10609	rs2914609-T	rs2914609	0	2914609	intergenic_variant	TRUE	NA	4e-6	5.3979400086720375	(EA)	0.234	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q23.1	5	121951366	FTMT, SRFBP1	FTMT - SRFBP1	ENSG00000181867	ENSG00000151304	NA	98533	10609	rs2914609-T	rs2914609	0	2914609	intergenic_variant	TRUE	NA	4e-6	5.3979400086720375	NA	0.213	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10q25.2	10	112994312	TCF7L2	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs34872471-T	rs34872471	0	34872471	intron_variant	FALSE	NA	4e-9	8.397940008672037	(EA)	0.259	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10q25.2	10	112994312	TCF7L2	TCF7L2	NA	NA	ENSG00000148737	NA	NA	rs34872471-T	rs34872471	0	34872471	intron_variant	FALSE	NA	1e-10	10	NA	0.262	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	18q21.2	18	50757579	MAPK4, MRO	MAPK4 - MRO	ENSG00000141639	ENSG00000134042	NA	25753	37541	rs36010659-T	rs36010659	0	36010659	intergenic_variant	TRUE	NA	9e-6	5.045757490560675	(EA)	0.258	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	20p11.23	20	19488358	SLC24A3	SLC24A3	NA	NA	ENSG00000185052	NA	NA	rs3790227-C	rs3790227	0	3790227	intron_variant	FALSE	NA	6e-6	5.221848749616356	NA	0.178	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p21.1	3	53523985	NR	CACNA1D	NA	NA	ENSG00000157388	NA	NA	rs3821843-G	rs3821843	0	3821843	intron_variant	FALSE	NA	5e-6	5.301029995663981	NA	0.18	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7q21.2	7	92609830	NR	CDK6	NA	NA	ENSG00000105810	NA	NA	rs42034-A	rs42034	0	42034	3_prime_UTR_variant	FALSE	NA	8e-8	7.096910013008056	(EA)	0.245	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7q21.2	7	92609830	NR	CDK6	NA	NA	ENSG00000105810	NA	NA	rs42034-A	rs42034	0	42034	3_prime_UTR_variant	FALSE	NA	2e-10	9.698970004336019	NA	0.27	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	8q24.3	8	140049552	TRAPPC9	TRAPPC9	NA	NA	ENSG00000167632	NA	NA	rs4631439-C	rs4631439	0	4631439	intron_variant	FALSE	NA	3e-6	5.522878745280337	(EA)	0.193	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	8q24.3	8	140049552	TRAPPC9	TRAPPC9	NA	NA	ENSG00000167632	NA	NA	rs4631439-C	rs4631439	0	4631439	intron_variant	FALSE	NA	3e-7	6.522878745280337	NA	0.19	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	17q25.1	17	75954135	ACOX1	ACOX1	NA	NA	ENSG00000161533	NA	NA	rs4788913-G	rs4788913	0	4788913	intron_variant	FALSE	NA	6e-6	5.221848749616356	NA	0.172	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q22.1	11	100772406	NR	ARHGAP42	NA	NA	ENSG00000165895	NA	NA	rs486023-G	rs486023	0	486023	intron_variant	FALSE	NA	4e-7	6.3979400086720375	NA	0.201	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p36.22	1	11836799	NR	CLCN6	NA	NA	ENSG00000011021	NA	NA	rs55892892-C	rs55892892	0	55892892	intron_variant	FALSE	NA	1e-10	10	(EA)	0.572	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q24.3	2	164050310	FIGN, GRB14	NA	NA	NA	NA	NA	NA	rs16849225-C	rs16849225	0	16849225	intron_variant	TRUE	NA	2e-19	18.69897000433602	NA	0.383	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p36.22	1	11802721	MTHFR	MTHFR	NA	NA	ENSG00000177000	NA	NA	rs17367504-A	rs17367504	0	17367504	intron_variant	FALSE	NA	8e-6	5.096910013008056	NA	0.221	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7q22.3	7	106771412	CCDC71L, PIK3CG	LINC01446 - LINC02577	ENSG00000205628	ENSG00000228742	NA	52959460	3543	rs17477177-T	rs17477177	0	17477177	intergenic_variant	TRUE	NA	9e-30	29.045757490560675	(EA)	0.564	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7q22.3	7	106771412	CCDC71L, PIK3CG	LINC01446 - LINC02577	ENSG00000205628	ENSG00000228742	NA	52959460	3543	rs17477177-T	rs17477177	0	17477177	intergenic_variant	TRUE	NA	1e-34	34	NA	0.555	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	17q21.32	17	46935905	GOSR2	GOSR2	NA	NA	ENSG00000108433	NA	NA	rs17608766-T	rs17608766	0	17608766	3_prime_UTR_variant	FALSE	NA	7e-10	9.154901959985743	(EA)	0.364	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	17q21.32	17	46935905	GOSR2	GOSR2	NA	NA	ENSG00000108433	NA	NA	rs17608766-T	rs17608766	0	17608766	3_prime_UTR_variant	FALSE	NA	2e-12	11.698970004336019	NA	0.397	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q31.22	4	147472512	TTC29, EDNRA	PRMT5P1 - EDNRA	ENSG00000249004	ENSG00000151617	NA	13191	8405	rs1878406-C	rs1878406	0	1878406	intergenic_variant	TRUE	NA	7e-6	5.154901959985743	NA	0.224	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q31.22	4	147472512	TTC29, EDNRA	PRMT5P1 - EDNRA	ENSG00000249004	ENSG00000151617	NA	13191	8405	rs1878406-C	rs1878406	0	1878406	intergenic_variant	TRUE	NA	2e-6	5.698970004336019	(EA)	0.269	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	8q24.12	8	119423572	NOV	CCN3	NA	NA	ENSG00000136999	NA	NA	rs2071518-C	rs2071518	0	2071518	3_prime_UTR_variant	FALSE	NA	3e-12	11.522878745280337	(EA)	0.313	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	8q24.12	8	119423572	NOV	CCN3	NA	NA	ENSG00000136999	NA	NA	rs2071518-C	rs2071518	0	2071518	3_prime_UTR_variant	FALSE	NA	8e-13	12.096910013008056	NA	0.291	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7p21.1	7	19009765	HDAC9, TWIST1	HDAC9 - TWIST1	ENSG00000048052	ENSG00000122691	NA	7349	11226	rs2107595-G	rs2107595	0	2107595	regulatory_region_variant	TRUE	NA	1e-11	11	(EA)	0.363	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7p21.1	7	19009765	HDAC9, TWIST1	HDAC9 - TWIST1	ENSG00000048052	ENSG00000122691	NA	7349	11226	rs2107595-G	rs2107595	0	2107595	regulatory_region_variant	TRUE	NA	3e-15	14.522878745280337	NA	0.366	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3q25.33	3	160652372	SCARNA7, ARL14	RPL6P8 - ARL14	ENSG00000242285	ENSG00000179674	NA	66585	24788	rs2178452-G	rs2178452	0	2178452	intergenic_variant	TRUE	NA	8e-7	6.096910013008056	NA	0.189	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	18q12.3	18	45516271	SLC14A2	SLC14A2	NA	NA	ENSG00000132874	NA	NA	rs2193635-C	rs2193635	0	2193635	intron_variant	FALSE	NA	3e-12	11.522878745280337	NA	0.311	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	18q12.3	18	45516271	SLC14A2	SLC14A2	NA	NA	ENSG00000132874	NA	NA	rs2193635-C	rs2193635	0	2193635	intron_variant	FALSE	NA	1e-12	12	(EA)	0.367	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	14q32.12	14	91892678	FBLN5	FBLN5	NA	NA	ENSG00000140092	NA	NA	rs2244643-A	rs2244643	0	2244643	intron_variant	FALSE	NA	1e-7	7	(EA)	0.23	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	14q32.12	14	91892678	FBLN5	FBLN5	NA	NA	ENSG00000140092	NA	NA	rs2244643-A	rs2244643	0	2244643	intron_variant	FALSE	NA	4e-9	8.397940008672037	NA	0.232	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7q21.2	7	92635096	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs2282978-T	rs2282978	0	2282978	intron_variant	FALSE	NA	3e-8	7.522878745280337	(EA)	0.231	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7q21.2	7	92635096	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs2282978-T	rs2282978	0	2282978	intron_variant	FALSE	NA	2e-9	8.698970004336019	NA	0.23	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q14.3	11	89491285	NOX4	NOX4	NA	NA	ENSG00000086991	NA	NA	rs2289125-A	rs2289125	0	2289125	5_prime_UTR_variant	FALSE	NA	1e-10	10	(EA)	0.311	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	11q14.3	11	89491285	NOX4	NOX4	NA	NA	ENSG00000086991	NA	NA	rs2289125-A	rs2289125	0	2289125	5_prime_UTR_variant	FALSE	NA	1e-14	14	NA	0.324	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p32.2	1	56543106	PPAP2B	PLPP3	NA	NA	ENSG00000162407	NA	NA	rs2404715-C	rs2404715	0	2404715	intron_variant	FALSE	NA	3e-6	5.522878745280337	(EA)	0.324	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p32.2	1	56543106	PPAP2B	PLPP3	NA	NA	ENSG00000162407	NA	NA	rs2404715-C	rs2404715	0	2404715	intron_variant	FALSE	NA	1e-7	7	NA	0.337	unit increase	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10q21.2	10	59879046	CCDC6	CCDC6	NA	NA	ENSG00000108091	NA	NA	rs2440907-G	rs2440907	0	2440907	intron_variant	FALSE	NA	3e-6	5.522878745280337	(EA)	0.188	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10q21.2	10	59879046	CCDC6	CCDC6	NA	NA	ENSG00000108091	NA	NA	rs2440907-G	rs2440907	0	2440907	intron_variant	FALSE	NA	1e-6	6	NA	0.177	unit decrease	Affymetrix [at least 2696785] (imputed)	N	pulse pressure measurement	http://www.ebi.ac.uk/efo/EFO_0005763	GCST007097	Genome-wide genotyping array	NA	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q25.2	1	180263615	NR	LHX4; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs7520941-T; rs10913956-T; rs12058637-T	rs7520941; rs10913956; rs12058637	0	NA	intron_variant; intron_variant; intron_variant	NA	0.012	1e-6	6	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.012	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q25.3	1	181570611	NR	CACNA1E; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10797729-G; rs3905011-A; rs10910963-C; rs7534913-G; rs10494541-G; rs10797732-T	rs10797729; rs3905011; rs10910963; rs7534913; rs10494541; rs10797732	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	1e-23	23	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q25.3	1	181570611	NR	CACNA1E; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10797729-A; rs3905011-A; rs10910963-C; rs7534913-G; rs10494541-G; rs10797732-T	rs10797729; rs3905011; rs10910963; rs7534913; rs10494541; rs10797732	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.255	2e-13	12.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.255	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q31.1	1	190026424	NR	N/A - BRINP3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2211345-G; rs6657359-A; rs10494629-A; rs4845225-A; rs12566811-A; rs10920351-T; rs2418877-C; rs6427944-T; rs4845222-G; rs1418797-A; rs7418463-C; rs17374565-T; rs4442368-G; rs11584992-A; rs12032930-C; rs10920379-T; rs4339868-G; rs2418881-T	rs2211345; rs6657359; rs10494629; rs4845225; rs12566811; rs10920351; rs2418877; rs6427944; rs4845222; rs1418797; rs7418463; rs17374565; rs4442368; rs11584992; rs12032930; rs10920379; rs4339868; rs2418881	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.015	7e-27	26.154901959985743	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.015	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q31.1	1	190026424	NR	N/A - BRINP3; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2211345-G; rs6657359-A; rs10494629-A; rs4845225-A; rs12566811-A; rs10920351-T; rs2418877-C; rs6427944-T; rs4845222-G; rs1418797-A; rs7418463-C; rs17374565-C; rs4442368-G; rs11584992-A; rs12032930-C; rs10920379-T; rs4339868-G; rs2418881-T	rs2211345; rs6657359; rs10494629; rs4845225; rs12566811; rs10920351; rs2418877; rs6427944; rs4845222; rs1418797; rs7418463; rs17374565; rs4442368; rs11584992; rs12032930; rs10920379; rs4339868; rs2418881	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; regulatory_region_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.336	4e-18	17.397940008672037	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.336	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q31.1	1	190681319	NR	LINC01720; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs6428024-T; rs1590496-C; rs1325222-A; rs16832598-C; rs4845171-G; rs1325220-T; rs4845243-A; rs11801346-G; rs10429895-C; rs16832590-C; rs6678095-C	rs6428024; rs1590496; rs1325222; rs16832598; rs4845171; rs1325220; rs4845243; rs11801346; rs10429895; rs16832590; rs6678095	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.0	1e-16	16	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q31.1	1	190681319	NR	LINC01720; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs6428024-G; rs1590496-C; rs1325222-A; rs16832598-C; rs4845171-G; rs1325220-T; rs4845243-A; rs11801346-G; rs10429895-C; rs16832590-C; rs6678095-C	rs6428024; rs1590496; rs1325222; rs16832598; rs4845171; rs1325220; rs4845243; rs11801346; rs10429895; rs16832590; rs6678095	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.129	4e-6	5.3979400086720375	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.129	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q31.2	1	192942842	NR	RN7SKP126 - ZNF101P2; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs842814-T; rs17525308-A; rs842805-G; rs710140-A; rs842798-T; rs7512163-C; rs7512241-A; rs10921293-A; rs6428143-G; rs842806-A; rs16835087-T; rs842783-T	rs842814; rs17525308; rs842805; rs710140; rs842798; rs7512163; rs7512241; rs10921293; rs6428143; rs842806; rs16835087; rs842783	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; regulatory_region_variant; regulatory_region_variant; intron_variant; regulatory_region_variant; intron_variant; intergenic_variant; intron_variant	NA	0.0	3e-6	5.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q31.3	1	194592718	NR	No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10921618-C; rs10801339-C	rs10921618; rs10801339	0	NA	intergenic_variant; intergenic_variant	NA	0.79	5e-6	5.301029995663981	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.79	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q32.1	1	202649545	NR	SYT2; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs946857-A; rs12021648-G; rs2095981-T; rs12404969-T; rs10920452-A; rs12038816-C; rs10920447-T; rs4950866-G; rs4950867-A; rs10920451-T; rs7517181-C; rs7550433-C; rs12404945-T; rs2153441-C	rs946857; rs12021648; rs2095981; rs12404969; rs10920452; rs12038816; rs10920447; rs4950866; rs4950867; rs10920451; rs7517181; rs7550433; rs12404945; rs2153441	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.203	9e-10	9.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.203	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q32.1	1;1	204191898;204192362	NR	KISS1; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; KISS1	NA	NA	NA	NA	NA	rs7538038-A; rs4951319-T; rs12097666-T; rs12040249-G; rs3924587-T; rs12568353-A; rs7524621-G; rs4951316-T	rs7538038; rs4951319; rs12097666; rs12040249; rs3924587; rs12568353; rs7524621; rs4951316	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; 5_prime_UTR_variant; intron_variant; intron_variant; intron_variant	NA	0.115	1e-6	6	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.115	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q32.1	1;1	204457245;204465799	NR	PIK3C2B; PIK3C2B	NA	NA	NA	NA	NA	rs2137255-C; rs12092943-G	rs2137255; rs12092943	0	NA	intron_variant; intron_variant	NA	0.002	2e-6	5.698970004336019	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.002	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q32.2	1	208022171	NR	LINC02767 - PLXNA2; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1193096-C; rs2767567-C; rs6659522-T; rs4844633-G; rs591752-C; rs6702082-C	rs1193096; rs2767567; rs6659522; rs4844633; rs591752; rs6702082	0	NA	TF_binding_site_variant; 3_prime_UTR_variant; 3_prime_UTR_variant; intron_variant; 3_prime_UTR_variant; intron_variant	NA	0.089	3e-10	9.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.089	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1q32.2	1	208906275	NR	N/A - LINC01774; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs1933553-C; rs17187806-T; rs12047788-C; rs12035141-T; rs17013655-C; rs12044772-C; rs17013631-G	rs1933553; rs17187806; rs12047788; rs12035141; rs17013655; rs12044772; rs17013631	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	0.204	1e-9	9	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.204	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.11	14	89411353	NR	FOXN3; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11626209-C; rs12147030-C; rs10484021-G; rs8009377-A; rs12431798-C	rs11626209; rs12147030; rs10484021; rs8009377; rs12431798	0	NA	intron_variant; missense_variant; intron_variant; intron_variant; intron_variant	NA	0.0	1e-9	9	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.12	14;14	91858850;91842885	NR	TC2N; No mapped genes; No mapped genes; No mapped genes; No mapped genes; TC2N; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs17127634-T; rs12891605-A; rs11846440-A; rs4904817-C; rs11160029-A; rs1884841-A; rs12891090-T; rs1884840-A; rs2402074-A	rs17127634; rs12891605; rs11846440; rs4904817; rs11160029; rs1884841; rs12891090; rs1884840; rs2402074	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	0.172	1e-8	8	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.172	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.12	14	92548144	NR	RIN3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs745381-C; rs7141006-G; rs943665-T; rs12893289-A	rs745381; rs7141006; rs943665; rs12893289	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.151	9e-6	5.045757490560675	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.151	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.12	14	92934516	NR	CHGA; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11625320-A; rs941582-T; rs2295397-T; rs9658644-G; rs2281513-C; rs750678-A; rs8013584-A	rs11625320; rs941582; rs2295397; rs9658644; rs2281513; rs750678; rs8013584	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant	NA	0.0	1e-21	21	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.12	14	92934516	NR	CHGA; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs11625320-A; rs941582-C; rs2295397-T; rs9658644-G; rs2281513-C; rs750678-A; rs8013584-A	rs11625320; rs941582; rs2295397; rs9658644; rs2281513; rs750678; rs8013584	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant	NA	0.287	5e-17	16.30102999566398	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.287	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.12	14	93972136	NR	ASB2; No mapped genes	NA	NA	NA	NA	NA	rs941490-A; rs4905125-T	rs941490; rs4905125	0	NA	intron_variant; intron_variant	NA	0.459	2e-23	22.69897000433602	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.459	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.12	14	93972136	NR	ASB2; No mapped genes	NA	NA	NA	NA	NA	rs941490-G; rs4905125-T	rs941490; rs4905125	0	NA	intron_variant; intron_variant	NA	0.32	2e-20	19.69897000433602	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.32	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.12	14	94032583	NR	OTUB2; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs8022950-C; rs1077948-C; rs17129431-T; rs10131610-C	rs8022950; rs1077948; rs17129431; rs10131610	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.002	3e-20	19.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.002	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.12	14	94032583	NR	OTUB2; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs8022950-C; rs1077948-T; rs17129431-T; rs10131610-C	rs8022950; rs1077948; rs17129431; rs10131610	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	0.189	1e-8	8	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.189	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.13	14	94753282	NR	RPSAP4 - GSC; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10142319-G; rs10142446-G; rs7157500-C	rs10142319; rs10142446; rs7157500	0	NA	intergenic_variant; intergenic_variant; intergenic_variant	NA	0.345	2e-18	17.69897000433602	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.345	NA	NA
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	14q32.13	14	94753282	NR	RPSAP4 - GSC; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10142319-G; rs10142446-G; rs7157500-T	rs10142319; rs10142446; rs7157500	0	NA	intergenic_variant; intergenic_variant; intergenic_variant	NA	0.16	1e-15	15	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.16	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2q24.3	2	168850753	NOSTRIN, SPC25	NOSTRIN, NOSTRIN, SPC25, SPC25	NA	NA	ENSG00000275326, ENSG00000163072, ENSG00000152253, ENSG00000277909	NA	NA	rs139707092-A	rs139707092	1	5836209	intron_variant	FALSE	0.3194	1e-14	14	NA	0.02967715	[0.022-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.3194	NA	0.02967715
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2q31.3	2	181443625	intergenic	LINC01934 - ITGA4	ENSG00000234663	ENSG00000115232	NA	34304	13577	rs6740847-G	rs6740847	0	6740847	intergenic_variant	TRUE	0.5638	9e-13	12.045757490560675	NA	0.02590063	[0.019-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.5638	NA	0.02590063
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2q35	2	218135259	CXCR2	CXCR2	NA	NA	ENSG00000180871	NA	NA	rs55799208-A	rs55799208	0	55799208	missense_variant	FALSE	0.0029	2e-41	40.69897000433602	NA	0.4845187	[0.41-0.55] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.0029	NA	0.4845187
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2q35	2	218156235	intergenic	CXCR2 - CXCR1	ENSG00000180871	ENSG00000163464	NA	18984	6606	rs114050631-T	rs114050631	0	114050631	regulatory_region_variant	TRUE	0.0106	3e-17	16.522878745280337	NA	0.1645126	[0.13-0.2] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.0106	NA	0.1645126
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2q35	2	218297999	PNKD	PNKD	NA	NA	ENSG00000127838	NA	NA	rs145013566-CA	rs145013566	0	145013566	intron_variant	FALSE	0.5243	9e-11	10.045757490560675	NA	0.02400607	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.5243	NA	0.02400607
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2p23.3	2	27508073	GCKR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs1260326-C	rs1260326	0	1260326	missense_variant	FALSE	0.6053	2e-18	17.69897000433602	NA	0.03202804	[0.025-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.6053	NA	0.03202804
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2q37.3	2	236867522	intergenic	NA	NA	NA	NA	NA	NA	rs9287604-C	rs9287604	0	9287604	intergenic_variant	TRUE	0.7326	3e-13	12.522878745280337	NA	0.02989953	[0.022-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.7326	NA	0.02989953
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2p21	2	43582208	THADA	THADA	NA	NA	ENSG00000115970	NA	NA	rs78487399-C	rs78487399	0	78487399	intron_variant	FALSE	0.0975	5e-11	10.301029995663981	NA	0.03988202	[0.028-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.0975	NA	0.03988202
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2p16.1	2	54760823	EML6	EML6	NA	NA	ENSG00000214595	NA	NA	rs200476039-A	rs200476039	0	200476039	intron_variant	FALSE	0.0517	7e-10	9.154901959985743	NA	0.05248104	[0.036-0.069] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.0517	NA	0.05248104
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2p15	2	61476184	RP11-355B11.2	XPO1, USP34-DT	NA	NA	ENSG00000082898, ENSG00000270820	NA	NA	rs10206089-A	rs10206089	0	10206089	non_coding_transcript_exon_variant	FALSE	0.3774	2e-9	8.698970004336019	NA	0.02373051	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.3774	NA	0.02373051
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	2q11.2	2	101160470	TBC1D8	TBC1D8	NA	NA	ENSG00000204634	NA	NA	rs7575217-G	rs7575217	0	7575217	intron_variant	FALSE	0.6725	6e-9	8.221848749616356	NA	0.02222061	[0.015-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.6725	NA	0.02222061
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	20q13.12	20	44413724	HNF4A	HNF4A	NA	NA	ENSG00000101076	NA	NA	rs1800961-T	rs1800961	0	1800961	missense_variant	FALSE	0.0314	9e-12	11.045757490560675	NA	0.07026628	[0.05-0.09] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.0314	NA	0.07026628
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	21q22.2	21	39091357	intergenic	NA - RPL23AP12	NA	ENSG00000228861	NA	NA	36211	rs9977672-A	rs9977672	0	9977672	intergenic_variant	TRUE	0.2583	5e-9	8.301029995663981	NA	0.0243021	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.2583	NA	0.0243021
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	22q11.21	22	17680392	BCL2L13	BCL2L13	NA	NA	ENSG00000099968	NA	NA	rs34891900-T	rs34891900	0	34891900	intron_variant	FALSE	0.5025	3e-9	8.522878745280337	NA	0.02130261	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.5025	NA	0.02130261
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	3q21.3	3	128603031	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	26945	16938	rs11359909-A	rs11359909	0	11359909	intergenic_variant	TRUE	0.8934	3e-25	24.522878745280337	NA	0.06062021	[0.049-0.072] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.8934	NA	0.06062021
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	3q21.3	3	128604581	intergenic	LINC01565 - RPN1	ENSG00000198685	ENSG00000163902	NA	28495	15388	rs6782228-C	rs6782228	0	6782228	intergenic_variant	TRUE	0.2678	9e-15	14.045757490560675	NA	0.03159961	[0.024-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.2678	NA	0.03159961
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	3q23	3	141208279	intergenic	SPSB4 - PXYLP1	ENSG00000175093	ENSG00000155893	NA	59668	20447	rs143699489-G	rs143699489	0	143699489	intergenic_variant	TRUE	0.1269	1e-11	11	NA	0.03656523	[0.026-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.1269	NA	0.03656523
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	3q23	3	141487958	RASA2	RASA2	NA	NA	ENSG00000155903	NA	NA	rs9819371-T	rs9819371	0	9819371	intron_variant	FALSE	0.065	6e-9	8.221848749616356	NA	0.04238032	[0.028-0.057] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.065	NA	0.04238032
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	3p22.1	3	42855023	KRBOX1, ACKR2, RP11-141M3.5	ACKR2, KRBOX1	NA	NA	ENSG00000144648, ENSG00000240747	NA	NA	rs9872570-A	rs9872570	0	9872570	intron_variant	FALSE	0.3848	2e-11	10.698970004336019	NA	0.02478297	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.3848	NA	0.02478297
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	3p21.31	3	47220756	KIF9-AS1	KIF9-AS1	NA	NA	ENSG00000227398	NA	NA	rs11920354-A	rs11920354	0	11920354	intron_variant	FALSE	0.3861	5e-9	8.301029995663981	NA	0.02146789	[0.014-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.3861	NA	0.02146789
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	NA	NA	NA	TADA2B, RP11-367J11.2	NA	NA	NA	NA	NA	NA	rs11931598-T	rs11931598	0	11931598	intron_variant	TRUE	0.4443	8e-10	9.096910013008056	NA	0.02235248	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4443	NA	0.02235248
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	4p16.3	4	711285	PCGF3	PCGF3	NA	NA	ENSG00000185619	NA	NA	rs11734460-T	rs11734460	0	11734460	intron_variant	FALSE	0.3122	4e-11	10.397940008672037	NA	0.02563131	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.3122	NA	0.02563131
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	4q12	4	54542832	intergenic	LINC02283 - LINC02260	ENSG00000248184	ENSG00000250456	NA	186878	60379	rs218265-C	rs218265	0	218265	intergenic_variant	TRUE	0.1571	1e-16	16	NA	0.04133874	[0.032-0.051] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.1571	NA	0.04133874
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	4q12	4	54635120	intergenic	LINC02260 - KIT	ENSG00000250456	ENSG00000157404	NA	27989	22798	rs58548501-TA	rs58548501	0	58548501	intergenic_variant	TRUE	0.4858	3e-11	10.522878745280337	NA	0.02374651	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4858	NA	0.02374651
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	4q13.3	4	71752058	GC	GC	NA	NA	ENSG00000145321	NA	NA	rs1352846-G	rs1352846	0	1352846	intron_variant	FALSE	0.2919	2e-10	9.698970004336019	NA	0.02509125	[0.017-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.2919	NA	0.02509125
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	6p21.1	6	42548053	intergenic	TRERF1 - UBR2	ENSG00000124496	ENSG00000024048	NA	96002	15976	rs16895831-T	rs16895831	0	16895831	regulatory_region_variant	TRUE	0.2033	7e-9	8.154901959985743	NA	0.02596701	[0.017-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.2033	NA	0.02596701
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	6q14.3	6	87128241	intergenic	RCN1P1 - ZNF292	ENSG00000215477	ENSG00000188994	NA	5553	24592	rs200638392-T	rs200638392	0	200638392	intergenic_variant	TRUE	0.4161	7e-16	15.154901959985743	NA	0.03081319	[0.023-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4161	NA	0.03081319
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	6q21	6	109286353	RP11-425D10.1, CCDC162P	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs9400271-A	rs9400271	0	9400271	non_coding_transcript_exon_variant	FALSE	0.4836	3e-21	20.522878745280337	NA	0.0339198	[0.027-0.041] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4836	NA	0.0339198
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	6q23.3	6	135099930	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs34208856-C	rs34208856	0	34208856	intron_variant	FALSE	0.2697	9e-19	18.045757490560675	NA	0.03624577	[0.028-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.2697	NA	0.03624577
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	NA	NA	NA	AHI1	NA	NA	NA	NA	NA	NA	chr6:135666064-TCACA	chr6:135666064	0	NA	NA	TRUE	0.5379	1e-13	13	NA	0.02725853	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.5379	NA	0.02725853
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	6q25.3	6	159049026	RP1-111C20.4	TAGAP-AS1	NA	NA	ENSG00000271913	NA	NA	rs212409-A	rs212409	0	212409	intron_variant	FALSE	0.5529	3e-12	11.522878745280337	NA	0.02529899	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.5529	NA	0.02529899
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	6p22.3	6	16744456	ATXN1	ATXN1	NA	NA	ENSG00000124788	NA	NA	rs1144700-T	rs1144700	0	1144700	intron_variant	FALSE	0.1789	6e-13	12.221848749616356	NA	0.03405242	[0.025-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.1789	NA	0.03405242
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	6p22.3	6	21381296	intergenic	NA	NA	NA	NA	NA	NA	rs6917586-A	rs6917586	0	6917586	intron_variant	TRUE	0.357	2e-11	10.698970004336019	NA	0.02533813	[0.018-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.357	NA	0.02533813
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	6p22.1	6	29955314	HLA-W	HLA-A - HLA-W	ENSG00000235657	ENSG00000235144	NA	9430	1282	rs9260620-G	rs9260620	0	9260620	intron_variant	TRUE	0.3358	2e-44	43.69897000433602	NA	0.05337227	[0.046-0.061] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.3358	NA	0.05337227
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	6p21.33	6	31274397	HLA-C, USP8P1	HLA-C - USP8P1	ENSG00000228299	ENSG00000236374	NA	2267	1175	rs2524079-A	rs2524079	0	2524079	intron_variant	TRUE	0.4168	6e-68	67.22184874961636	NA	0.06325533	[0.056-0.07] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4168	NA	0.06325533
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	7p21.3	7	7978549	GLCCI1, RPA3-AS1	GLCCI1	NA	NA	ENSG00000106415	NA	NA	rs7804306-A	rs7804306	0	7804306	intron_variant	FALSE	0.0606	4e-9	8.397940008672037	NA	0.04459301	[0.03-0.059] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.0606	NA	0.04459301
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	4q13.3	4	73838282	CXCL6	CXCL6	NA	NA	ENSG00000124875	NA	NA	rs16850073-T	rs16850073	0	16850073	3_prime_UTR_variant	FALSE	0.3748	2e-45	44.69897000433602	NA	0.05262755	[0.045-0.06] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.3748	NA	0.05262755
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	4q13.3	4	74094279	CXCL2	PPBPP2 - CXCL2	ENSG00000248848	ENSG00000081041	NA	38880	2761	rs11725704-G	rs11725704	0	11725704	regulatory_region_variant	TRUE	0.3762	3e-85	84.52287874528034	NA	0.07240236	[0.065-0.08] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.3762	NA	0.07240236
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	4q21.22	4	82631138	SCD5	SCD5	NA	NA	ENSG00000145284	NA	NA	rs28476539-A	rs28476539	0	28476539	3_prime_UTR_variant	FALSE	0.1825	5e-10	9.301029995663981	NA	0.02900354	[0.02-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.1825	NA	0.02900354
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	4q24	4	105140377	AC004069.2	RNU6-351P - TET2	ENSG00000251906	ENSG00000168769	NA	165606	5498	rs7679673-A	rs7679673	0	7679673	intron_variant	TRUE	0.3745	2e-10	9.698970004336019	NA	0.02349569	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.3745	NA	0.02349569
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	5p15.33	5	1104823	SLC12A7	SLC12A7, SLC12A7	NA	NA	ENSG00000113504, ENSG00000276482	NA	NA	rs35188965-T	rs35188965	0	35188965	intron_variant	FALSE	0.5794	1e-9	9	NA	0.02199592	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.5794	NA	0.02199592
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	5q35.2	5	173778222	intergenic	LINC01484 - LINC01485	ENSG00000253686	ENSG00000254211	NA	31943	305	rs791357-C	rs791357	0	791357	intergenic_variant	TRUE	0.7204	6e-24	23.221848749616356	NA	0.0409616	[0.033-0.049] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.7204	NA	0.0409616
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	5q35.3	5	179757487	MAML1	MAML1, MAML1	NA	NA	ENSG00000283780, ENSG00000161021	NA	NA	rs76025697-A	rs76025697	0	76025697	intron_variant	FALSE	0.4194	4e-12	11.397940008672037	NA	0.02513983	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4194	NA	0.02513983
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	5p15.33	5	1285859	TERT	TERT	NA	NA	ENSG00000164362	NA	NA	rs7705526-A	rs7705526	0	7705526	intron_variant	FALSE	0.329	6e-19	18.221848749616356	NA	0.03464376	[0.027-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.329	NA	0.03464376
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	5q13.2	5	69297096	CCDC125	CCDC125, CCDC125	NA	NA	ENSG00000277868, ENSG00000183323	NA	NA	rs72767881-T	rs72767881	0	72767881	intron_variant	FALSE	0.4445	4e-15	14.397940008672037	NA	0.02838679	[0.021-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4445	NA	0.02838679
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	5q13.2	5	72432861	intergenic	YBX1P5 - ZNF366	ENSG00000251108	ENSG00000178175	NA	14526	7042	rs2338224-G	rs2338224	0	2338224	intergenic_variant	TRUE	0.8787	7e-15	14.154901959985743	NA	0.04273679	[0.032-0.054] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.8787	NA	0.04273679
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	5q31.1	5	132341949	AC034220.3, SLC22A4	MIR3936HG, SLC22A4	NA	NA	ENSG00000233006, ENSG00000197208	NA	NA	rs10075801-G	rs10075801	0	10075801	intron_variant	FALSE	0.4855	4e-22	21.397940008672037	NA	0.03509937	[0.028-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.4855	NA	0.03509937
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	5q31.3	5	142130697	NDFIP1	NDFIP1	NA	NA	ENSG00000131507	NA	NA	rs11405616-CA	rs11405616	0	11405616	intron_variant	FALSE	0.6036	9e-17	16.045757490560675	NA	0.03096152	[0.024-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.6036	NA	0.03096152
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	5q32	5	148820990	intergenic	HTR4 - ADRB2	ENSG00000164270	ENSG00000169252	NA	143755	5621	rs2082382-A	rs2082382	0	2082382	regulatory_region_variant	TRUE	0.5467	9e-19	18.045757490560675	NA	0.03217761	[0.025-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.5467	NA	0.03217761
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum neutrophil eosinophil counts	170,384 European ancestry individuals	NA	6p21.32	6	32623176	intergenic	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735	NA	33328	5003	rs9271588-C	rs9271588	0	9271588	intergenic_variant	TRUE	0.5051	4e-66	65.39794000867204	NA	0.06142442	[0.054-0.068] unit increase	Affymetrix [~ 2500000] (imputed)	N	neutrophil count, eosinophil count	http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004842	GCST004613	Genome-wide genotyping array	0.5051	NA	0.06142442
2017-01-09	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Daytime sleep phenotypes	874 European ancestry individuals	NA	19p13.3	19	2893407	AC119403.1, ZNF57, ZNF556, ZNF555, ZNF77	ZNF556 - ZNF57	ENSG00000172000	ENSG00000171970	NA	9962	7491	rs11671007-G	rs11671007	0	11671007	intergenic_variant	TRUE	NR	8e-6	5.096910013008056	(daytime resting duration, weekdays)	0.1667	[0.094-0.24] unit increase	Affymetrix [7141204] (imputed)	N	daytime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007828	GCST003518	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3p24.1	3	29414666	RBMS3, RPS12P5, RBMS3-AS3, RBMS3-AS2	RBMS3	NA	NA	ENSG00000144642	NA	NA	rs17023449-G	rs17023449	0	17023449	intron_variant	FALSE	NR	8e-6	5.096910013008056	(number of awakenings after sleep onset, weekdays)	0.3081	[0.17-0.44] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5p13.1	5	38762186	CTD-2127H9.1, RP11-122C5.2, OSMR, LIFR-AS1	OSMR-AS1	NA	NA	ENSG00000249740	NA	NA	rs10045504-C	rs10045504	0	10045504	intron_variant	FALSE	NR	3e-6	5.522878745280337	(number of awakenings after sleep onset, weekdays)	0.1114	[0.064-0.158] unit increase	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q11.2	5	57646731	AC008780.1, ACTBL2, SALL4P1	LINCR-0003 - NA	ENSG00000249436	NA	NA	26915	NA	rs76395602-C	rs76395602	0	76395602	intergenic_variant	TRUE	NR	5e-6	5.301029995663981	(number of awakenings after sleep onset, weekdays)	0.1229	[0.07-0.175] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q22.1	5	111990503	NREP, NREP-AS1, HMGN1P14, EPB41L4A	NREP-AS1, NREP	NA	NA	ENSG00000250095, ENSG00000134986	NA	NA	rs140529718-A	rs140529718	0	140529718	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(number of awakenings after sleep onset, weekdays)	0.3623	[0.21-0.52] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q22.2	5	112212065	EPB41L4A, CTC-459M5.2, EPB41L4A-AS1, SNORA13	EPB41L4A	NA	NA	ENSG00000129595	NA	NA	rs146128029-C	rs146128029	0	146128029	intron_variant	FALSE	NR	5e-6	5.301029995663981	(number of awakenings after sleep onset, weekdays)	0.3315	[0.19-0.47] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6q24.1	6	140701399	MIR4465	MIR4465 - RPS3AP24	ENSG00000264390	ENSG00000217684	NA	17516	60130	rs7740706-G	rs7740706	0	7740706	intron_variant	TRUE	NR	4e-6	5.3979400086720375	(number of awakenings after sleep onset, weekdays)	0.09867	[0.057-0.14] unit increase	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	8q21.2	8	84363832	RALYL, TPM3P3	RALYL	NA	NA	ENSG00000184672	NA	NA	rs118149821-T	rs118149821	0	118149821	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(number of awakenings after sleep onset, weekdays)	0.327	[0.19-0.47] unit increase	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	14q12	14	32760933	AKAP6, NPAS3	AKAP6	NA	NA	ENSG00000151320	NA	NA	rs1955510-G	rs1955510	0	1955510	intron_variant	FALSE	NR	7e-6	5.154901959985743	(number of awakenings after sleep onset, weekdays)	0.1396	[0.079-0.2] unit increase	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	16q21	16	60428802	RP11-354I13.2, AC009081.1, GNPATP	NPAP1L - NA	ENSG00000278499	NA	NA	69322	NA	rs12919634-C	rs12919634	0	12919634	intron_variant	TRUE	NR	2e-6	5.698970004336019	(number of awakenings after sleep onset, weekdays)	0.1134	[0.067-0.16] unit increase	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	19p12	19	20691932	CTD-2542C24.2, ZNF626, VN1R79P, ZNF66P	ZNF626 - VN1R79P	ENSG00000188171	ENSG00000269885	NA	30336	66508	rs6511152-G	rs6511152	0	6511152	non_coding_transcript_exon_variant	TRUE	NR	1e-6	6	(number of awakenings after sleep onset, weekdays)	0.1105	[0.066-0.155] unit decrease	Affymetrix [7141204] (imputed)	N	sleep quality	http://www.ebi.ac.uk/efo/EFO_0005272	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1q25.2	1	177782204	SEC16B	LINC01741 - NA	ENSG00000236720	NA	NA	69929	NA	rs113466017-C	rs113466017	0	113466017	intron_variant	TRUE	NR	2e-6	5.698970004336019	(resting duration)	0.5584	[0.33-0.79] unit decrease	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3p14.3	3	56401367	ERC2, CCDC66, RNA5SP133, FAM208A	ERC2	NA	NA	ENSG00000187672	NA	NA	rs1546060-C	rs1546060	0	1546060	intron_variant	FALSE	NR	5e-6	5.301029995663981	(resting duration)	0.1922	[0.11-0.27] unit increase	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q31.3	5	144767179	NA	NA	NA	NA	NA	NA	NA	rs166016-C	rs166016	0	166016	intergenic_variant	TRUE	NR	8e-6	5.096910013008056	(resting duration)	0.2162	[0.12-0.31] unit decrease	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	8p23.2	8	4393762	CSMD1, Metazoa_SRP	CSMD1	NA	NA	ENSG00000183117	NA	NA	rs11988906-G	rs11988906	0	11988906	intron_variant	FALSE	NR	2e-6	5.698970004336019	(resting duration)	0.1925	[0.11-0.27] unit increase	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	9p21.1	9	30331305	NA	NA - LINC01242	NA	ENSG00000280683	NA	NA	57630	rs186927647-G	rs186927647	0	186927647	intergenic_variant	TRUE	NR	4e-7	6.3979400086720375	(resting duration)	0.3237	[0.2-0.45] unit decrease	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	11q24.3	11	129698007	TMEM45B, NFRKB, PRDM10, BARX2	LINC01395 - NA	ENSG00000281097	NA	NA	80738	NA	rs141697342-G	rs141697342	0	141697342	regulatory_region_variant	TRUE	NR	1e-6	6	(resting duration)	0.6406	[0.38-0.9] unit increase	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	16p12.1	16	27231559	NSMCE1, KDM8, IL4R, EEF1A1P38	NSMCE1	NA	NA	ENSG00000169189	NA	NA	rs11643134-C	rs11643134	0	11643134	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(resting duration)	0.1974	[0.11-0.28] unit increase	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	17q11.2	17	29164844	MYO18A, TWF1P1, TIAF1, CRYBA1	MYO18A	NA	NA	ENSG00000196535	NA	NA	rs10438797-T	rs10438797	0	10438797	intron_variant	FALSE	NR	9e-6	5.045757490560675	(resting duration)	0.1956	[0.11-0.28] unit decrease	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	20p12.1	20	12482649	PA2G4P2	NA - SLC24A3	NA	ENSG00000185052	NA	NA	6729993	rs10211700-T	rs10211700	0	10211700	intergenic_variant	TRUE	NR	1e-6	6	(resting duration)	0.344	[0.2-0.48] unit decrease	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	21q22.13	21	36817379	HLCS, HLCS-IT1, RNA5SP491, SIM2	HLCS	NA	NA	ENSG00000159267	NA	NA	rs16994508-T	rs16994508	0	16994508	intron_variant	FALSE	NR	1e-6	6	(resting duration)	0.7399	[0.44-1.04] unit decrease	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1p35.3	1	28514428	RCC1, snoU13, SNHG3, SNORA73B, SNORA73A, PRDX3P2	RCC1	NA	NA	ENSG00000180198	NA	NA	rs56272623-T	rs56272623	0	56272623	intron_variant	FALSE	NR	2e-6	5.698970004336019	(resting duration, weekdays)	0.7624	[0.45-1.08] unit increase	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	2q24.2	2	159207648	TANC1, WDSUB1, BAZ2B, GSTM3P2	TANC1	NA	NA	ENSG00000115183	NA	NA	rs111640264-A	rs111640264	0	111640264	intron_variant	FALSE	NR	3e-7	6.522878745280337	(resting duration, weekdays)	0.5271	[0.33-0.73] unit decrease	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	2q32.1	2	182584998	PDE1A, DNAJC10, FRZB	PDE1A - DNAJC10	ENSG00000115252	ENSG00000077232	NA	61806	131257	rs1918700-T	rs1918700	0	1918700	intergenic_variant	TRUE	NR	5e-6	5.301029995663981	(resting duration, weekdays)	0.2334	[0.13-0.33] unit decrease	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3p22.1	3	42359309	EIF4BP4, SALL4P6, LYZL4, CCK	EIF4BP4 - LYZL4	ENSG00000229572	ENSG00000157093	NA	16942	37774	rs33449-C	rs33449	0	33449	intergenic_variant	TRUE	NR	2e-6	5.698970004336019	(resting duration, weekdays)	0.6513	[0.38-0.92] unit decrease	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	10q21.1	10	58941240	BICC1, FAM133CP, PHYHIPL	RN7SKP196 - LINC00844	ENSG00000252076	ENSG00000237949	NA	71712	58242	rs72806511-T	rs72806511	0	72806511	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(resting duration, weekdays)	0.508	[0.29-0.72] unit decrease	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	18p11.31	18	3107406	MYOM1, RNU7-25P, LPIN2, MYL12A	MYOM1	NA	NA	ENSG00000101605	NA	NA	rs141348977-T	rs141348977	0	141348977	intron_variant	FALSE	NR	9e-6	5.045757490560675	(resting duration, weekdays)	0.4693	[0.26-0.68] unit increase	Affymetrix [7141204] (imputed)	N	nighttime rest measurement	http://www.ebi.ac.uk/efo/EFO_0007827	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1p34.3	1	35314387	ZMYM4, SNORA62, ZMYM4-AS1, RNY5P1	ZMYM4	NA	NA	ENSG00000146463	NA	NA	rs12069385-T	rs12069385	0	12069385	intron_variant	FALSE	NR	8e-8	7.096910013008056	(sleep duration)	0.8877	[0.56-1.21] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	1q23.1	1	158617176	SPTA1, OR10Z1, OR10X1, OR6P1	SPTA1	NA	NA	ENSG00000163554	NA	NA	rs2022003-T	rs2022003	0	2022003	intron_variant	FALSE	NR	6e-6	5.221848749616356	(sleep duration)	0.2353	[0.13-0.34] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	2p25.3	2	386912	AC105393.1, FAM150B, ACP1, SH3YL1	LINC01865 - NA	ENSG00000233684	NA	NA	44794	NA	rs28405493-C	rs28405493	0	28405493	intergenic_variant	TRUE	NR	5e-6	5.301029995663981	(sleep duration)	0.2221	[0.13-0.32] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	NA	NA	NA	SCG2, AP1S3, WDFY1, HIGD1AP4	NA	NA	NA	NA	NA	NA	chr2:224506070-T	chr2:224506070	0	NA	NA	TRUE	NR	5e-6	5.301029995663981	(sleep duration)	0.655	[0.37-0.94] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3q24	3	143247876	SLC9A9, PBX2P1, SLC9A9-AS1, CHST2	PBX2P1 - SLC9A9	ENSG00000244171	ENSG00000181804	NA	70259	17346	rs17635531-A	rs17635531	0	17635531	intergenic_variant	TRUE	NR	7e-7	6.154901959985743	(sleep duration)	0.403	[0.24-0.56] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3q26.2	3	171131724	TNIK, MIR569, SLC2A2, KLF7P1	TNIK	NA	NA	ENSG00000154310	NA	NA	rs115419280-C	rs115419280	0	115419280	intron_variant	FALSE	NR	1e-6	6	(sleep duration)	0.6266	[0.37-0.88] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	4q33	4	169342292	NEK1, SH3RF1, RPL6P12	SH3RF1 - NEK1	ENSG00000154447	ENSG00000137601	NA	71336	50517	rs4535301-T	rs4535301	0	4535301	regulatory_region_variant	TRUE	NR	8e-6	5.096910013008056	(sleep duration)	0.2074	[0.12-0.3] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	4q35.1	4	184958576	MIR4455, HELT, MIR3945, ACSL1	MIR4455 - LINC02437	ENSG00000263458	ENSG00000248517	NA	20136	30421	rs4276324-G	rs4276324	0	4276324	regulatory_region_variant	TRUE	NR	6e-6	5.221848749616356	(sleep duration)	0.3548	[0.2-0.51] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q35.2	5	174767801	CTD-2532K18.1, MIR4634, MSX2, HIGD1AP3	MIR4634 - NA	ENSG00000266890	NA	NA	16014	NA	rs11739656-T	rs11739656	0	11739656	intron_variant	TRUE	NR	1e-6	6	(sleep duration)	0.3246	[0.19-0.45] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6p24.3	6	9914134	OFCC1	OFCC1	NA	NA	ENSG00000181355	NA	NA	rs73720625-T	rs73720625	0	73720625	intron_variant	FALSE	NR	8e-6	5.096910013008056	(sleep duration)	0.5341	[0.3-0.77] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	7p21.3	7	8118953	ICA1, AC006042.6, GLCCI1	ICA1	NA	NA	ENSG00000003147	NA	NA	rs56314523-A	rs56314523	0	56314523	intron_variant	FALSE	NR	6e-6	5.221848749616356	(sleep duration)	0.2393	[0.14-0.34] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	13q22.3	13	78234678	RNF219-AS1, RP11-203P2.1, RNY3P3, RPL31P54	OBI1-AS1	NA	NA	ENSG00000234377	NA	NA	rs12583965-G	rs12583965	0	12583965	intron_variant	FALSE	NR	9e-6	5.045757490560675	(sleep duration)	0.4226	[0.24-0.61] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	13q34	13	110103485	COL4A1, RN7SKP10, COL4A2	RN7SL783P - COL4A1	ENSG00000265885	ENSG00000187498	NA	5334	45478	rs16854-C	rs16854	0	16854	intron_variant	TRUE	NR	1e-6	6	(sleep duration)	0.3088	[0.18-0.43] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	18q22.3	18	71620714	NA	LINC01541 - NA	ENSG00000260676	NA	NA	41758	NA	rs185549704-T	rs185549704	0	185549704	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	(sleep duration)	0.5929	[0.34-0.85] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3p24.1	3	30550452	TGFBR2, GADL1	LINC01985 - TGFBR2	ENSG00000227260	ENSG00000163513	NA	23259	56149	rs4955158-T	rs4955158	0	4955158	TF_binding_site_variant	TRUE	NR	5e-6	5.301029995663981	(sleep duration, weekdays)	0.6493	[0.37-0.93] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3p14.2	3	58661848	FAM3D, FAM107A, C3orf67, ACOX2	FAM3D	NA	NA	ENSG00000198643	NA	NA	rs77510899-T	rs77510899	0	77510899	intron_variant	FALSE	NR	4e-6	5.3979400086720375	(sleep duration, weekdays)	0.7111	[0.41-1.01] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	3q26.33	3	181539408	SOX2-OT, RP11-4B14.3, SOX2	SOX2-OT	NA	NA	ENSG00000242808	NA	NA	rs10937060-C	rs10937060	0	10937060	intron_variant	FALSE	NR	5e-6	5.301029995663981	(sleep duration, weekdays)	0.2534	[0.14-0.36] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	5q35.2	5	175443899	DRD1, SFXN1, ARL2BPP6, HRH2	DRD1	NA	NA	ENSG00000184845	NA	NA	rs265981-G	rs265981	0	265981	5_prime_UTR_variant	FALSE	NR	5e-6	5.301029995663981	(sleep duration, weekdays)	0.2206	[0.13-0.32] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	6p25.1	6	6065527	NRN1, F13A1, PKMP5, MIR5683	NRN1 - F13A1	ENSG00000124785	ENSG00000124491	NA	57922	78557	rs4960162-T	rs4960162	0	4960162	intergenic_variant	TRUE	NR	7e-6	5.154901959985743	(sleep duration, weekdays)	0.2067	[0.12-0.3] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	7p21.1	7	19804174	TMEM196, TWISTNB, MIR3146, RPL21P28	TMEM196 - NA	ENSG00000173452	NA	NA	30557	NA	rs10267417-T	rs10267417	0	10267417	intergenic_variant	TRUE	NR	6e-6	5.221848749616356	(sleep duration, weekdays)	0.3287	[0.19-0.47] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	8q21.3	8	86866815	CNBD1, CNGB3, GOLGA2P1	CNBD1	NA	NA	ENSG00000176571	NA	NA	rs2453452-A	rs2453452	0	2453452	intron_variant	FALSE	NR	6e-6	5.221848749616356	(sleep duration, weekdays)	0.3612	[0.21-0.52] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	10q21.2	10	61376864	TMEM26	NA - TMEM26	NA	ENSG00000196932	NA	NA	29778	rs4948275-T	rs4948275	0	4948275	intergenic_variant	TRUE	NR	4e-6	5.3979400086720375	(sleep duration, weekdays)	0.2073	[0.12-0.29] unit increase	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-01-16	27126917	Spada J	2016-04-29	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/27126917	Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.	Night sleep phenotypes	941 European ancestry individuals	NA	13q33.1	13	101179397	NALCN, NALCN-AS1, LINC00411	NALCN	NA	NA	ENSG00000102452	NA	NA	rs79972364-C	rs79972364	0	79972364	intron_variant	FALSE	NR	7e-6	5.154901959985743	(sleep duration, weekdays)	0.5811	[0.33-0.84] unit decrease	Affymetrix [7141204] (imputed)	N	sleep duration	http://www.ebi.ac.uk/efo/EFO_0005271	GCST003542	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p25.3	6	2050557	GMDS	GMDS	NA	NA	ENSG00000112699	NA	NA	rs115986297-G	rs115986297	0	115986297	intron_variant	FALSE	0.5429	7e-15	14.154901959985743	NA	0.02773504	[0.021-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5429	NA	0.02773504
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	NA	NA	NA	RREB1	NA	NA	NA	NA	NA	NA	chr6:7229619-A	chr6:7229619	0	NA	NA	TRUE	0.2963	2e-11	10.698970004336019	NA	0.02596959	[0.018-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2963	NA	0.02596959
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p22.3	6	16287961	GMPR	GMPR	NA	NA	ENSG00000137198	NA	NA	rs6459467-A	rs6459467	0	6459467	intron_variant	FALSE	0.38	3e-10	9.522878745280337	NA	0.02300312	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.38	NA	0.02300312
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p22.2	6	26072764	intergenic	H1-2 - HFE	ENSG00000187837	ENSG00000010704	NA	16294	14517	rs144861591-T	rs144861591	0	144861591	intergenic_variant	TRUE	0.0771	1e-162	162	NA	0.1809882	[0.17-0.19] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0771	NA	0.1809882
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p22.2	6	26090951	HFE	HFE	NA	NA	ENSG00000010704	NA	NA	rs1799945-G	rs1799945	0	1799945	missense_variant	FALSE	0.1505	2e-103	102.69897000433602	NA	0.1067434	[0.097-0.116] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.1505	NA	0.1067434
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p22.1	6	29949108	HLA-A	HLA-A - HLA-W	ENSG00000235657	ENSG00000235144	NA	3224	7488	rs9260313-C	rs9260313	0	9260313	3_prime_UTR_variant	TRUE	0.2875	1e-15	15	NA	0.03200038	[0.024-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2875	NA	0.03200038
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p21.33	6	31274306	HLA-C, USP8P1	HLA-C - USP8P1	ENSG00000228299	ENSG00000236374	NA	2176	1266	rs2524081-C	rs2524081	0	2524081	intron_variant	TRUE	0.1374	5e-11	10.301029995663981	NA	0.03378154	[0.024-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.1374	NA	0.03378154
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	NA	NA	NA	HLA-DQB1-AS1	NA	NA	NA	NA	NA	NA	chr6:32623434-C	chr6:32623434	0	NA	NA	TRUE	0.3455	1e-32	32	NA	0.04648763	[0.039-0.054] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.3455	NA	0.04648763
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p21.1	6	43763914	intergenic	MRPS18A - VEGFA	ENSG00000096080	ENSG00000112715	NA	76123	6270	rs78003500-T	rs78003500	0	78003500	regulatory_region_variant	TRUE	0.057	3e-19	18.522878745280337	NA	0.06933705	[0.054-0.084] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.057	NA	0.06933705
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p21.1	6	43774889	VEGFA	VEGFA	NA	NA	ENSG00000112715	NA	NA	rs833070-C	rs833070	0	833070	non_coding_transcript_exon_variant	FALSE	0.4996	1e-20	20	NA	0.03284456	[0.026-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.4996	NA	0.03284456
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p21.1	6	43834169	intergenic	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	47682	10709	rs869197558-C	rs869197558	1	5875851	intron_variant	TRUE	0.8428	3e-13	12.522878745280337	NA	0.03596526	[0.026-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.8428	NA	0.03596526
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p21.1	6	43842065	intergenic	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	55578	2813	rs9472135-C	rs9472135	0	9472135	intron_variant	TRUE	0.3059	5e-21	20.30102999566398	NA	0.03615679	[0.029-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.3059	NA	0.03615679
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p21.1	6	43973400	intergenic	NA - SCIRT	NA	ENSG00000237686	NA	NA	22323	rs17287978-C	rs17287978	0	17287978	regulatory_region_variant	TRUE	0.0487	7e-15	14.154901959985743	NA	0.06446452	[0.048-0.081] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0487	NA	0.06446452
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p21.1	6	44062274	RP5-1120P11.1	SCIRT	NA	NA	ENSG00000237686	NA	NA	rs833805-G	rs833805	0	833805	non_coding_transcript_exon_variant	FALSE	0.8865	5e-31	30.30102999566398	NA	0.06978199	[0.058-0.082] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.8865	NA	0.06978199
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6p12.2	6	52860723	RP11-392A23.4	GSTA11P	NA	NA	ENSG00000230375	NA	NA	rs3996993-C	rs3996993	0	3996993	intron_variant	FALSE	0.5282	5e-9	8.301029995663981	NA	0.02094444	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5282	NA	0.02094444
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6q22.33	6	127127104	RSPO3	RSPO3	NA	NA	ENSG00000146374	NA	NA	rs1936807-G	rs1936807	0	1936807	intron_variant	FALSE	0.5182	5e-12	11.301029995663981	NA	0.02453562	[0.018-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5182	NA	0.02453562
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	6q23.3	6	135090090	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs9376090-C	rs9376090	0	9376090	intron_variant	FALSE	0.2598	3e-34	33.52287874528034	NA	0.04957227	[0.042-0.058] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2598	NA	0.04957227
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	7p22.3	7	631957	PRKAR1B	PRKAR1B	NA	NA	ENSG00000188191	NA	NA	rs35750745-CA	rs35750745	0	35750745	intron_variant	FALSE	0.5878	4e-12	11.397940008672037	NA	0.02548659	[0.018-0.033] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.5878	NA	0.02548659
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	7p22.3	7	1246931	intergenic	UNCX - MICALL2	ENSG00000164853	ENSG00000164877	NA	9605	181534	rs62435145-T	rs62435145	0	62435145	regulatory_region_variant	TRUE	0.6915	7e-14	13.154901959985743	NA	0.02919609	[0.022-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.6915	NA	0.02919609
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	7p22.1	7	6710127	ZNF12, PMS2CL	ZNF12 - PMS2CL	ENSG00000164631	ENSG00000187953	NA	3180	1	rs6967414-A	rs6967414	0	6967414	intergenic_variant	TRUE	0.1068	4e-10	9.397940008672037	NA	0.03590529	[0.025-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.1068	NA	0.03590529
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	7q22.1	7	100325440	PMS2P1	PMS2P1	NA	NA	ENSG00000078319	NA	NA	rs184562466-T	rs184562466	0	184562466	intron_variant	FALSE	0.0073	2e-13	12.698970004336019	NA	0.1545303	[0.11-0.2] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0073	NA	0.1545303
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	7q22.1	7	100486348	NYAP1	NYAP1	NA	NA	ENSG00000166924	NA	NA	rs546810441-A	rs546810441	0	546810441	intron_variant	FALSE	0.0079	7e-36	35.15490195998574	NA	0.2848409	[0.24-0.33] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0079	NA	0.2848409
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	7q22.1	7	100641799	TFR2	TFR2	NA	NA	ENSG00000106327	NA	NA	rs531909210-A	rs531909210	0	531909210	intron_variant	FALSE	0.0045	2e-16	15.698970004336019	NA	0.235309	[0.18-0.29] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0045	NA	0.235309
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	7q22.1	7	100677821	GNB2	GNB2	NA	NA	ENSG00000172354	NA	NA	rs62482253-A	rs62482253	0	62482253	splice_region_variant	FALSE	0.0068	2e-12	11.698970004336019	NA	0.1776727	[0.13-0.23] unit decrease	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.0068	NA	0.1776727
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Hemoglobin concentration	172,925 European ancestry individuals	NA	7q22.1	7	100701281	POP7	GIGYF1 - POP7	ENSG00000146830	ENSG00000172336	NA	7031	4840	rs11772705-C	rs11772705	0	11772705	regulatory_region_variant	TRUE	0.2881	3e-14	13.522878745280337	NA	0.02979821	[0.022-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	hemoglobin measurement	http://www.ebi.ac.uk/efo/EFO_0004509	GCST004615	Genome-wide genotyping array	0.2881	NA	0.02979821
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3p12.1	3	84964010	CADM2	CADM2	NA	NA	ENSG00000175161	NA	NA	rs17733561-A	rs17733561	0	17733561	intron_variant	FALSE	0.981	3e-6	5.522878745280337	NA	0.205	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.981	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144489641	Intergenic	NA - KRT18P51	NA	ENSG00000250504	NA	NA	82597	rs75588466-A	rs75588466	0	75588466	intron_variant	TRUE	0.96	1e-6	6	NA	0.196	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.96	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	14q32.13	14	94371805	Intergenic	SERPINA2 - SERPINA1	ENSG00000274821	ENSG00000277377	NA	5107	4942	rs112635299-T	rs112635299	0	112635299	intron_variant	TRUE	0.02	3e-7	6.522878745280337	NA	0.186	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.02	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	19q13.2	19	40812029	Intergenic	CYP2T1P	NA	NA	ENSG00000233622	NA	NA	rs4803370-A	rs4803370	0	4803370	non_coding_transcript_exon_variant	FALSE	0.978	3e-6	5.522878745280337	NA	0.166	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.978	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	89183662	Intergenic	RNU6-907P - GPRIN3	ENSG00000212226	ENSG00000185477	NA	52709	52721	rs76565382-C	rs76565382	0	76565382	intergenic_variant	TRUE	0.028	4e-6	5.3979400086720375	NA	0.166	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.028	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	19q13.2	19	40815169	Intergenic	CYP2T1P - CYP2F2P	ENSG00000233622	ENSG00000237118	NA	3069	3245	rs147893869-C	rs147893869	0	147893869	intron_variant	TRUE	0.978	1e-6	6	NA	0.165	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.978	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	14q32.13	14	94378610	SERPINA1	SERPINA1, SERPINA1	NA	NA	ENSG00000197249, ENSG00000277377	NA	NA	rs28929474-T	rs28929474	0	28929474	missense_variant	FALSE	0.023	1e-6	6	NA	0.162	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.023	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	19q13.2	19	40809421	AK097370	CYP2T1P	NA	NA	ENSG00000233622	NA	NA	rs149812270-A	rs149812270	0	149812270	non_coding_transcript_exon_variant	FALSE	0.981	4e-6	5.3979400086720375	NA	0.16	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.981	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	19q13.2	19	40806017	EGLN2	RAB4B-EGLN2, EGLN2	NA	NA	ENSG00000171570, ENSG00000269858	NA	NA	rs117139969-T	rs117139969	0	117139969	non_coding_transcript_exon_variant	FALSE	0.981	4e-6	5.3979400086720375	NA	0.159	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.981	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	14q32.13	14	94290606	SERPINA10	SERPINA10, SERPINA10	NA	NA	ENSG00000278767, ENSG00000140093	NA	NA	rs45505795-C	rs45505795	0	45505795	synonymous_variant	FALSE	0.036	1e-7	7	NA	0.155	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.036	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	105922801	NPNT	NPNT	NA	NA	ENSG00000168743	NA	NA	rs7664805-C	rs7664805	0	7664805	intron_variant	FALSE	0.085	1e-6	6	NA	0.141	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.085	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	5q33.3	5	159046359	EBF1	EBF1	NA	NA	ENSG00000164330	NA	NA	rs17717876-T	rs17717876	0	17717876	intron_variant	FALSE	0.043	1e-6	6	NA	0.138	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.043	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.1	4	88591861	Intergenic	RN7SKP244 - HERC3	ENSG00000252322	ENSG00000138641	NA	7889	573	rs113228472-A	rs113228472	0	113228472	intron_variant	TRUE	0.04	4e-6	5.3979400086720375	NA	0.126	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.04	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	16q22.2	16	71766142	AP1G1	AP1G1	NA	NA	ENSG00000166747	NA	NA	rs12928939-G	rs12928939	0	12928939	intron_variant	FALSE	0.107	4e-6	5.3979400086720375	(AA)	0.118	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.107	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	7p22.3	7	2525634	LFNG	LFNG	NA	NA	ENSG00000106003	NA	NA	rs893239-C	rs893239	0	893239	intron_variant	FALSE	0.523	1e-6	6	(AA)	0.117	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.523	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	6q25.2	6	152320521	SYNE1	SYNE1	NA	NA	ENSG00000131018	NA	NA	rs7741183-C	rs7741183	0	7741183	intron_variant	FALSE	0.162	4e-7	6.3979400086720375	(AA)	0.108	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.162	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q12	4	58178629	Intergenic	SRIP1 - NA	ENSG00000248660	NA	NA	75195	NA	rs4865309-G	rs4865309	0	4865309	intergenic_variant	TRUE	0.76	4e-6	5.3979400086720375	(AA)	0.1	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.76	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q22.2	11	102881870	Intergenic	BOLA3P1 - RNU7-159P	ENSG00000255469	ENSG00000238562	NA	1024	22022	rs17368890-T	rs17368890	0	17368890	regulatory_region_variant	TRUE	0.934	2e-6	5.698970004336019	NA	0.096	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.934	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	105889390	Intergenic	INTS12	NA	NA	ENSG00000138785	NA	NA	rs72673889-A	rs72673889	0	72673889	intron_variant	FALSE	0.936	3e-6	5.522878745280337	NA	0.094	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.936	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	105893145	Intergenic	INTS12	NA	NA	ENSG00000138785	NA	NA	rs72673891-A	rs72673891	0	72673891	intron_variant	FALSE	0.936	3e-6	5.522878745280337	NA	0.094	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.936	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11p15.4	11	11239853	Intergenic	MTND5P21	NA	NA	ENSG00000255123	NA	NA	rs4076943-T	rs4076943	0	4076943	non_coding_transcript_exon_variant	FALSE	0.725	2e-7	6.698970004336019	(AA)	0.094	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.725	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	105887024	Intergenic	INTS12	NA	NA	ENSG00000138785	NA	NA	rs72673888-T	rs72673888	0	72673888	intron_variant	FALSE	0.936	3e-6	5.522878745280337	NA	0.093	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.936	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	105884727	Intergenic	INTS12	NA	NA	ENSG00000138785	NA	NA	rs187455071-A	rs187455071	0	187455071	intron_variant	FALSE	0.936	3e-6	5.522878745280337	NA	0.093	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.936	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	105710713	GSTCD	GSTCD, INTS12	NA	NA	ENSG00000138780, ENSG00000138785	NA	NA	rs11727735-A	rs11727735	0	11727735	intron_variant	FALSE	0.062	4e-6	5.3979400086720375	NA	0.092	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.062	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q24	4	105879222	Intergenic	INTS12	NA	NA	ENSG00000138785	NA	NA	rs11730660-A	rs11730660	0	11730660	intron_variant	FALSE	0.936	4e-6	5.3979400086720375	NA	0.092	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.936	NA	NA
2017-06-15	28118524	Saxena R	2017-01-24	Arthritis Rheumatol	www.ncbi.nlm.nih.gov/pubmed/28118524	A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.	Rheumatoid arthritis	97 African admixed Arab ancestry cases, 410 non-African admixed Arab ancestry cases, 4 Arab ancestry cases, 56 African admixed Arab ancestry controls, 290 non-African admixed Arab ancestry controls, 6 Arab ancestry controls	283 Arab ancestry cases, 221 Arab ancestry controls	6p21.32	6	32484011	HLA-DRB1	HLA-DRB9 - HLA-DRB5	ENSG00000226035	ENSG00000198502	NA	10511	33342	rs9269234-G	rs9269234	0	9269234	intergenic_variant	TRUE	0.65	5e-11	10.301029995663981	NA	1.75	[1.48-2.06]	Illumina [7000653] (imputed)	N	rheumatoid arthritis	http://www.ebi.ac.uk/efo/EFO_0000685	GCST004172	Genome-wide genotyping array	0.65	1.75	NA
2017-06-15	28118524	Saxena R	2017-01-24	Arthritis Rheumatol	www.ncbi.nlm.nih.gov/pubmed/28118524	A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.	Rheumatoid arthritis	97 African admixed Arab ancestry cases, 410 non-African admixed Arab ancestry cases, 4 Arab ancestry cases, 56 African admixed Arab ancestry controls, 290 non-African admixed Arab ancestry controls, 6 Arab ancestry controls	283 Arab ancestry cases, 221 Arab ancestry controls	5p13.3	5	30404961	CDH6	NA	NA	NA	NA	NA	NA	rs12519788-G	rs12519788	0	12519788	intergenic_variant	TRUE	0.79	1e-8	8	NA	1.79	[1.47-2.19]	Illumina [7000653] (imputed)	N	rheumatoid arthritis	http://www.ebi.ac.uk/efo/EFO_0000685	GCST004172	Genome-wide genotyping array	0.79	1.79	NA
2017-06-15	28118524	Saxena R	2017-01-24	Arthritis Rheumatol	www.ncbi.nlm.nih.gov/pubmed/28118524	A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.	Rheumatoid arthritis	97 African admixed Arab ancestry cases, 410 non-African admixed Arab ancestry cases, 4 Arab ancestry cases, 56 African admixed Arab ancestry controls, 290 non-African admixed Arab ancestry controls, 6 Arab ancestry controls	283 Arab ancestry cases, 221 Arab ancestry controls	17p13.2	17	4599900	SMTNL2, GGT6	SMTNL2	NA	NA	ENSG00000188176	NA	NA	rs12601925-G	rs12601925	0	12601925	intron_variant	FALSE	0.86	7e-7	6.154901959985743	NA	1.79	[1.42-2.26]	Illumina [7000653] (imputed)	N	rheumatoid arthritis	http://www.ebi.ac.uk/efo/EFO_0000685	GCST004172	Genome-wide genotyping array	0.86	1.79	NA
2017-06-15	28118524	Saxena R	2017-01-24	Arthritis Rheumatol	www.ncbi.nlm.nih.gov/pubmed/28118524	A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.	Rheumatoid arthritis	97 African admixed Arab ancestry cases, 410 non-African admixed Arab ancestry cases, 4 Arab ancestry cases, 56 African admixed Arab ancestry controls, 290 non-African admixed Arab ancestry controls, 6 Arab ancestry controls	283 Arab ancestry cases, 221 Arab ancestry controls	3q13.2	3	112852072	CD200R1	CD200R1L - CD200R1	ENSG00000206531	ENSG00000163606	NA	5216	69133	rs9860428-C	rs9860428	0	9860428	intergenic_variant	TRUE	0.38	5e-8	7.301029995663981	NA	1.59	[1.35-1.88]	Illumina [7000653] (imputed)	N	rheumatoid arthritis	http://www.ebi.ac.uk/efo/EFO_0000685	GCST004172	Genome-wide genotyping array	0.38	1.59	NA
2017-06-15	28118524	Saxena R	2017-01-24	Arthritis Rheumatol	www.ncbi.nlm.nih.gov/pubmed/28118524	A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.	Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive)	357 African admixed and non-African admixed Arab ancestry cases, 352 African admixed and non-African admixed Arab ancestry controls	234 Arab ancestry cases, 225 Arab ancestry controls	6p21.32	6	32484011	HLA-DRB1	HLA-DRB9 - HLA-DRB5	ENSG00000226035	ENSG00000198502	NA	10511	33342	rs9269234-G	rs9269234	0	9269234	intergenic_variant	TRUE	0.65	6e-16	15.221848749616356	NA	2.14	[1.78-2.57]	Illumina [7000653] (imputed)	N	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0007837, http://www.ebi.ac.uk/efo/EFO_0007791	GCST004174	Genome-wide genotyping array	0.65	2.14	NA
2017-06-15	28118524	Saxena R	2017-01-24	Arthritis Rheumatol	www.ncbi.nlm.nih.gov/pubmed/28118524	A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.	Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive)	357 African admixed and non-African admixed Arab ancestry cases, 352 African admixed and non-African admixed Arab ancestry controls	234 Arab ancestry cases, 225 Arab ancestry controls	5p13.3	5	30404961	CDH6	NA	NA	NA	NA	NA	NA	rs12519788-G	rs12519788	0	12519788	intergenic_variant	TRUE	0.79	5e-8	7.301029995663981	NA	1.82	[1.47-2.26]	Illumina [7000653] (imputed)	N	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0007837, http://www.ebi.ac.uk/efo/EFO_0007791	GCST004174	Genome-wide genotyping array	0.79	1.82	NA
2017-06-15	28118524	Saxena R	2017-01-24	Arthritis Rheumatol	www.ncbi.nlm.nih.gov/pubmed/28118524	A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.	Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive)	357 African admixed and non-African admixed Arab ancestry cases, 352 African admixed and non-African admixed Arab ancestry controls	234 Arab ancestry cases, 225 Arab ancestry controls	17p13.2	17	4599900	SMTNL2, GGT6	SMTNL2	NA	NA	ENSG00000188176	NA	NA	rs12601925-G	rs12601925	0	12601925	intron_variant	FALSE	0.86	6e-9	8.221848749616356	NA	2.15	[1.66-2.78]	Illumina [7000653] (imputed)	N	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0007837, http://www.ebi.ac.uk/efo/EFO_0007791	GCST004174	Genome-wide genotyping array	0.86	2.15	NA
2017-06-15	28118524	Saxena R	2017-01-24	Arthritis Rheumatol	www.ncbi.nlm.nih.gov/pubmed/28118524	A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.	Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive)	357 African admixed and non-African admixed Arab ancestry cases, 352 African admixed and non-African admixed Arab ancestry controls	234 Arab ancestry cases, 225 Arab ancestry controls	3q13.2	3	112852072	CD200R1	CD200R1L - CD200R1	ENSG00000206531	ENSG00000163606	NA	5216	69133	rs9860428-C	rs9860428	0	9860428	intergenic_variant	TRUE	0.38	4e-7	6.3979400086720375	NA	1.6	[1.33-1.92]	Illumina [7000653] (imputed)	N	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0007837, http://www.ebi.ac.uk/efo/EFO_0007791	GCST004174	Genome-wide genotyping array	0.38	1.6	NA
2017-03-29	27632927	Einarsdottir E	2016-09-16	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27632927	Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.	Otitis media	803 Finnish ancestry child cases, 2,073 Finnish ancestry controls	NA	6q22.1	6	116448435	NR	DSE - CBX3P9	ENSG00000111817	ENSG00000217241	NA	3574	4579	rs17077968-?	rs17077968	0	17077968	intron_variant	TRUE	NR	3e-6	5.522878745280337	NA	NA	NA	Illumina [319683]	N	Otitis media	http://www.ebi.ac.uk/efo/EFO_0004992	GCST003827	Genome-wide genotyping array	NA	NA	NA
2017-03-29	27632927	Einarsdottir E	2016-09-16	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27632927	Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.	Otitis media	803 Finnish ancestry child cases, 2,073 Finnish ancestry controls	NA	9q22.33	9	99472041	NR	STX17-AS1	NA	NA	ENSG00000255145	NA	NA	rs649057-?	rs649057	0	649057	intron_variant	FALSE	NR	2e-6	5.698970004336019	NA	NA	NA	Illumina [319683]	N	Otitis media	http://www.ebi.ac.uk/efo/EFO_0004992	GCST003827	Genome-wide genotyping array	NA	NA	NA
2017-03-29	27632927	Einarsdottir E	2016-09-16	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27632927	Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.	Otitis media	803 Finnish ancestry child cases, 2,073 Finnish ancestry controls	NA	Xq26.3	X	137829405	NR	NA	NA	NA	NA	NA	NA	rs7891968-?	rs7891968	0	7891968	intron_variant	TRUE	NR	2e-6	5.698970004336019	NA	NA	NA	Illumina [319683]	N	Otitis media	http://www.ebi.ac.uk/efo/EFO_0004992	GCST003827	Genome-wide genotyping array	NA	NA	NA
2017-03-29	27632927	Einarsdottir E	2016-09-16	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27632927	Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.	Otitis media	803 Finnish ancestry child cases, 2,073 Finnish ancestry controls	NA	19q13.2	19	40407632	PLD3, HIPK4, PRX, SERTAD1, SERTAD3, BLVRB	PRX	NA	NA	ENSG00000105227	NA	NA	rs16974263-A	rs16974263	0	16974263	non_coding_transcript_exon_variant	FALSE	0.094	2e-7	6.698970004336019	NA	1.59	1.33-1.89	Illumina [319683]	N	Otitis media	http://www.ebi.ac.uk/efo/EFO_0004992	GCST003827	Genome-wide genotyping array	0.094	1.59	NA
2017-03-29	27632927	Einarsdottir E	2016-09-16	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27632927	Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.	Otitis media (chronic)	512 Finnish ancestry child cases, 2,073 Finnish ancestry controls	1,466 child cases, 3,394 controls	19q13.2	19	40407632	HIPK4, PRX, SERTAD1, PLD3, SERTAD3, BLVRB	PRX	NA	NA	ENSG00000105227	NA	NA	rs16974263-A	rs16974263	0	16974263	non_coding_transcript_exon_variant	FALSE	0.094	3e-8	7.522878745280337	(Finnish)	1.75	1.43-2.14	Illumina [319683]	N	Otitis media	http://www.ebi.ac.uk/efo/EFO_0004992	GCST003828	Genome-wide genotyping array	0.094	1.75	NA
2017-03-29	27632927	Einarsdottir E	2016-09-16	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27632927	Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.	Otitis media (chronic)	512 Finnish ancestry child cases, 2,073 Finnish ancestry controls	1,466 child cases, 3,394 controls	9q22.33	9	99472041	NA	STX17-AS1	NA	NA	ENSG00000255145	NA	NA	rs649057-?	rs649057	0	649057	intron_variant	FALSE	NR	7e-7	6.154901959985743	(Finnish)	NA	NA	Illumina [319683]	N	Otitis media	http://www.ebi.ac.uk/efo/EFO_0004992	GCST003828	Genome-wide genotyping array	NA	NA	NA
2017-03-29	27632927	Einarsdottir E	2016-09-16	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27632927	Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.	Otitis media (recurrent)	702 Finnish ancestry child cases, 2,073 Finnish ancestry controls	NA	8p23.2	8	5287261	NR	NA	NA	NA	NA	NA	NA	rs9314561-?	rs9314561	0	9314561	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	NA	NA	NA	Illumina [319683]	N	Otitis media	http://www.ebi.ac.uk/efo/EFO_0004992	GCST003829	Genome-wide genotyping array	NA	NA	NA
2017-03-29	27632927	Einarsdottir E	2016-09-16	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27632927	Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.	Otitis media (recurrent)	702 Finnish ancestry child cases, 2,073 Finnish ancestry controls	NA	6q22.1	6	116448435	NR	DSE - CBX3P9	ENSG00000111817	ENSG00000217241	NA	3574	4579	rs17077968-?	rs17077968	0	17077968	intron_variant	TRUE	NR	3e-6	5.522878745280337	NA	NA	NA	Illumina [319683]	N	Otitis media	http://www.ebi.ac.uk/efo/EFO_0004992	GCST003829	Genome-wide genotyping array	NA	NA	NA
2017-03-29	27632927	Einarsdottir E	2016-09-16	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27632927	Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.	Otitis media (recurrent)	702 Finnish ancestry child cases, 2,073 Finnish ancestry controls	NA	Xq26.3	X	137829405	NR	NA	NA	NA	NA	NA	NA	rs7891968-?	rs7891968	0	7891968	intron_variant	TRUE	NR	6e-6	5.221848749616356	NA	NA	NA	Illumina [319683]	N	Otitis media	http://www.ebi.ac.uk/efo/EFO_0004992	GCST003829	Genome-wide genotyping array	NA	NA	NA
2017-03-29	27632927	Einarsdottir E	2016-09-16	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/27632927	Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.	Otitis media (recurrent)	702 Finnish ancestry child cases, 2,073 Finnish ancestry controls	NA	19q13.2	19	40407632	PLD3, HIPK4, PRX, SERTAD1, SERTAD3, BLVRB	PRX	NA	NA	ENSG00000105227	NA	NA	rs16974263-A	rs16974263	0	16974263	non_coding_transcript_exon_variant	FALSE	0.094	1e-7	7	NA	1.64	1.36-1.96	Illumina [319683]	N	Otitis media	http://www.ebi.ac.uk/efo/EFO_0004992	GCST003829	Genome-wide genotyping array	0.094	1.64	NA
2017-04-21	28002826	D'Adamo CR	2016-12-22	J Nutrigenet Nutrigenomics	www.ncbi.nlm.nih.gov/pubmed/28002826	The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations.	Carotenoid levels (alpha-carotene)	433 Old Order Amish individuals	NA	2p21	2	46182327	PRKCE	PRKCE	NA	NA	ENSG00000171132	NA	NA	rs2594495-A	rs2594495	0	2594495	intron_variant	FALSE	0.04	1e-8	8	NA	0.37	[0.25-0.49] μmol/L increase	Affymetrix [2193082] (imputed)	N	alpha-carotene measurement	http://www.ebi.ac.uk/efo/EFO_0007893	GCST003938	Genome-wide genotyping array	0.04	NA	0.37
2017-04-21	28002826	D'Adamo CR	2016-12-22	J Nutrigenet Nutrigenomics	www.ncbi.nlm.nih.gov/pubmed/28002826	The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations.	Carotenoid levels (alpha-carotene)	433 Old Order Amish individuals	NA	4q34.3	4	181257153	LINC00290	LINC00290 - LINC02500	ENSG00000248197	ENSG00000249460	NA	98004	3289	rs17830069-G	rs17830069	0	17830069	intergenic_variant	TRUE	0.02	3e-8	7.522878745280337	NA	0.38	[0.24-0.52] μmol/L increase	Affymetrix [2193082] (imputed)	N	alpha-carotene measurement	http://www.ebi.ac.uk/efo/EFO_0007893	GCST003938	Genome-wide genotyping array	0.02	NA	0.38
2017-04-21	28002826	D'Adamo CR	2016-12-22	J Nutrigenet Nutrigenomics	www.ncbi.nlm.nih.gov/pubmed/28002826	The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations.	Carotenoid levels (alpha-carotene)	433 Old Order Amish individuals	NA	1q41	1	223684349	CAPN8, CAPN2	CAPN8 - RNU6-1248P	ENSG00000203697	ENSG00000212398	NA	18626	5702	rs12137025-C	rs12137025	0	12137025	regulatory_region_variant	TRUE	0.07	4e-8	7.3979400086720375	NA	0.19	[0.13-0.25] μmol/L increase	Affymetrix [2193082] (imputed)	N	alpha-carotene measurement	http://www.ebi.ac.uk/efo/EFO_0007893	GCST003938	Genome-wide genotyping array	0.07	NA	0.19
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	1p22.3	1	87273536	intergenic	LINC02801 - LMO4	ENSG00000284240	ENSG00000143013	NA	8795	55344	rs1537061-C	rs1537061	0	1537061	regulatory_region_variant	TRUE	0.0983	3e-15	14.522878745280337	NA	0.04627965	[0.035-0.058] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.0983	NA	0.04627965
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	1q32.1	1	205684628	SLC45A3	Metazoa_SRP - NUCKS1	ENSG00000278007	ENSG00000069275	NA	321	28194	rs6685188-C	rs6685188	0	6685188	intergenic_variant	TRUE	0.7656	5e-12	11.301029995663981	NA	0.02805518	[0.02-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.7656	NA	0.02805518
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	2p25.1	2	8299499	LINC00299	LINC00299	NA	NA	ENSG00000236790	NA	NA	rs10165200-A	rs10165200	0	10165200	intron_variant	FALSE	0.3713	1e-9	9	NA	0.02186009	[0.015-0.029] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.3713	NA	0.02186009
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	2q34	2	212858270	AC079610.1	PCED1CP - MIR4776-1	ENSG00000231254	ENSG00000266354	NA	25325	67987	rs75497452-A	rs75497452	0	75497452	intron_variant	TRUE	0.094	4e-10	9.397940008672037	NA	0.03773182	[0.026-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.094	NA	0.03773182
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	3p26.2	3	3076322	IL5RA	IL5RA	NA	NA	ENSG00000091181	NA	NA	rs3217673-T	rs3217673	0	3217673	intron_variant	FALSE	0.5048	4e-20	19.397940008672037	NA	0.0326002	[0.026-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.5048	NA	0.0326002
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	3p21.31	3	46209161	CCR3	CCR3	NA	NA	ENSG00000183625	NA	NA	rs3181077-T	rs3181077	0	3181077	intron_variant	FALSE	0.7172	1e-19	19	NA	0.03513781	[0.028-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.7172	NA	0.03513781
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	NA	NA	NA	SCD5	NA	NA	NA	NA	NA	NA	chr4:83550168-A	chr4:83550168	0	NA	NA	TRUE	0.1864	4e-9	8.397940008672037	NA	0.02643483	[0.018-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.1864	NA	0.02643483
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	5q31.3	5	142102704	intergenic	GNPDA1 - NDFIP1	ENSG00000113552	ENSG00000131507	NA	89663	6075	rs62384625-T	rs62384625	0	62384625	intergenic_variant	TRUE	0.3701	3e-10	9.522878745280337	NA	0.02283405	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.3701	NA	0.02283405
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	6p21.33	6	31475005	HCP5	HCP5, HCP5, HCP5	NA	NA	ENSG00000237105, ENSG00000206337, ENSG00000230389	NA	NA	rs3131643-A	rs3131643	0	3131643	intron_variant	FALSE	0.1597	2e-24	23.69897000433602	NA	0.04853096	[0.039-0.058] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.1597	NA	0.04853096
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	6q23.3	6	135178322	MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513	NA	75266	2986	rs9376098-A	rs9376098	0	9376098	intergenic_variant	TRUE	0.3498	6e-9	8.221848749616356	NA	0.021378	[0.014-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.3498	NA	0.021378
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	7q21.2	7	92606850	CDK6	CDK6	NA	NA	ENSG00000105810	NA	NA	rs8179-C	rs8179	0	8179	3_prime_UTR_variant	FALSE	0.7916	8e-9	8.096910013008056	NA	0.02495519	[0.016-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.7916	NA	0.02495519
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	7q34	7	143384849	ZYX	ZYX, ZYX	NA	NA	ENSG00000285443, ENSG00000159840	NA	NA	rs11772895-C	rs11772895	0	11772895	intron_variant	FALSE	0.2788	3e-9	8.522878745280337	NA	0.02311239	[0.015-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.2788	NA	0.02311239
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	8p23.1	8	7042814	DEFA7P	DEFA7P - DEFA5	ENSG00000206042	ENSG00000285251	NA	3375	12490	rs10086568-A	rs10086568	0	10086568	intergenic_variant	TRUE	0.3223	3e-16	15.522878745280337	NA	0.03102688	[0.024-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.3223	NA	0.03102688
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	8q23.1	8	105561297	ZFPM2	ZFPM2, ZFPM2-AS1	NA	NA	ENSG00000169946, ENSG00000251003	NA	NA	rs3832566-C	rs3832566	0	3832566	intron_variant	FALSE	0.2724	2e-9	8.698970004336019	NA	0.02347503	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.2724	NA	0.02347503
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	10p12.1	10	26452245	APBB1IP	APBB1IP	NA	NA	ENSG00000077420	NA	NA	rs2992262-T	rs2992262	0	2992262	intron_variant	FALSE	0.6074	3e-12	11.522878745280337	NA	0.02510943	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.6074	NA	0.02510943
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	11p15.5	11	307961	IFITM2	IFITM2	NA	NA	ENSG00000185201	NA	NA	rs3888187-C	rs3888187	0	3888187	5_prime_UTR_variant	FALSE	0.5142	7e-11	10.154901959985743	NA	0.0236202	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.5142	NA	0.0236202
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	11q14.3	11	90199744	CHORDC1	NAALAD2 - CHORDC1	ENSG00000077616	ENSG00000110172	NA	6850	685	rs200830364-T	rs200830364	1	199548575	intergenic_variant	TRUE	0.371	7e-10	9.154901959985743	NA	0.02312203	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.371	NA	0.02312203
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	14q11.2	14	23107989	intergenic	LMLN2 - CEBPE	ENSG00000283654	ENSG00000092067	NA	3000	9317	rs9743723-T	rs9743723	0	9743723	intergenic_variant	TRUE	0.7198	4e-39	38.39794000867204	NA	0.05143034	[0.044-0.059] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.7198	NA	0.05143034
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	16p13.11	16	16029602	ABCC1	ABCC1, ABCC1	NA	NA	ENSG00000278183, ENSG00000103222	NA	NA	rs924135-T	rs924135	0	924135	intron_variant	FALSE	0.6139	1e-10	10	NA	0.02315483	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.6139	NA	0.02315483
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	17q21.1	17	39987295	PSMD3	PSMD3	NA	NA	ENSG00000108344	NA	NA	rs4065321-T	rs4065321	0	4065321	intron_variant	FALSE	0.5363	2e-47	46.69897000433602	NA	0.05072893	[0.044-0.058] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.5363	NA	0.05072893
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	18q21.33	18	63253621	BCL2	BCL2	NA	NA	ENSG00000171791	NA	NA	rs17758695-T	rs17758695	0	17758695	intron_variant	FALSE	0.0299	1e-51	51	NA	0.1562393	[0.14-0.18] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.0299	NA	0.1562393
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	19q13.11	19	33260946	intergenic	SLC7A10 - CEBPA	ENSG00000130876	ENSG00000245848	NA	35096	38988	rs12151289-C	rs12151289	0	12151289	intergenic_variant	TRUE	0.0316	2e-66	65.69897000433602	NA	0.1770172	[0.16-0.2] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.0316	NA	0.1770172
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	16q24.2	16	88500925	ZFPM1	ZFPM1	NA	NA	ENSG00000179588	NA	NA	rs74035509-T	rs74035509	0	74035509	intron_variant	FALSE	0.079	5e-9	8.301029995663981	NA	0.03985692	[0.027-0.053] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.079	NA	0.03985692
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	19q13.32	19	44908822	APOE	APOE	NA	NA	ENSG00000130203	NA	NA	rs7412-T	rs7412	0	7412	missense_variant	FALSE	0.0792	4e-20	19.397940008672037	NA	0.05980158	[0.047-0.073] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0792	NA	0.05980158
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	19p13.2	19	11181407	KANK2	KANK2	NA	NA	ENSG00000197256	NA	NA	rs74180173-T	rs74180173	0	74180173	intron_variant	FALSE	0.084	3e-57	56.52287874528034	NA	0.1033283	[0.091-0.116] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.084	NA	0.1033283
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p25.3	6	376329	intergenic	DUSP22 - IRF4	ENSG00000112679	ENSG00000137265	NA	24974	15423	rs55713716-A	rs55713716	0	55713716	intergenic_variant	TRUE	0.7493	1e-19	19	NA	0.04562594	[0.036-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.7493	NA	0.04562594
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p25.3	6	577820	EXOC2	EXOC2	NA	NA	ENSG00000112685	NA	NA	rs9504361-G	rs9504361	0	9504361	intron_variant	FALSE	0.4484	4e-17	16.397940008672037	NA	0.03123781	[0.024-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.4484	NA	0.03123781
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p22.1	6	29832434	HCG4P8	HLA-G - HCP5B	ENSG00000235680	ENSG00000281831	NA	1309	39461	rs12662618-C	rs12662618	0	12662618	intergenic_variant	TRUE	0.1015	1e-17	17	NA	0.05062162	[0.039-0.062] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.1015	NA	0.05062162
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p22.1	6	30102205	TRIM31-AS1	RNF39 - TRIM31	ENSG00000204618	ENSG00000225130	NA	26356	692	rs1111180-C	rs1111180	0	1111180	intergenic_variant	TRUE	0.5666	2e-35	34.69897000433602	NA	0.04474978	[0.038-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.5666	NA	0.04474978
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p21.33	6	31353072	XXbac-BPG248L24.12	LINC02571 - HLA-B	ENSG00000256166	ENSG00000206450	NA	51430	800	rs35735140-C	rs35735140	0	35735140	intron_variant	TRUE	0.0632	9e-33	32.045757490560675	NA	0.08825474	[0.074-0.103] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.0632	NA	0.08825474
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p21.33	6	31411338	MICA	MICA, MICA, MICA, MICA, MICA	NA	NA	ENSG00000233051, ENSG00000204520, ENSG00000231225, ENSG00000183214, ENSG00000235233	NA	NA	rs1131896-A	rs1131896	0	1131896	missense_variant	FALSE	0.2312	2e-28	27.69897000433602	NA	0.04672725	[0.038-0.055] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.2312	NA	0.04672725
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p21.32	6	32654582	HLA-DQB1	HLA-DQA1 - HLA-DQB1	ENSG00000196735	ENSG00000206237	NA	7520	4885	rs17613465-G	rs17613465	0	17613465	intergenic_variant	TRUE	0.8098	5e-12	11.301029995663981	NA	0.03277746	[0.023-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.8098	NA	0.03277746
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p21.32	6	33077723	HLA-DPB1, HLA-DPA1	HLA-DPA1, HLA-DPA1, HLA-DPA1, HLA-DPA1, HLA-DPA1, HLA-DPA1, HLA-DPB1, HLA-DPB1, HLA-DPB1, HLA-DPB1, HLA-DPB1, HLA-DPB1	NA	NA	ENSG00000224103, ENSG00000206291, ENSG00000231389, ENSG00000228163, ENSG00000229685, ENSG00000236177, ENSG00000215048, ENSG00000237710, ENSG00000223865, ENSG00000229295, ENSG00000226826, ENSG00000230708	NA	NA	rs2856816-C	rs2856816	0	2856816	intron_variant	FALSE	0.092	7e-15	14.154901959985743	NA	0.04810228	[0.036-0.06] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.092	NA	0.04810228
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p21.31	6	35635342	FKBP5	FKBP5	NA	NA	ENSG00000096060	NA	NA	rs7760951-C	rs7760951	0	7760951	intron_variant	FALSE	0.8278	1e-10	10	NA	0.03076058	[0.021-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.8278	NA	0.03076058
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p21.31	6	35749266	ARMC12	ARMC12 - CLPSL2	ENSG00000157343	ENSG00000196748	NA	187	27328	rs2766547-A	rs2766547	0	2766547	intergenic_variant	TRUE	0.5102	4e-9	8.397940008672037	NA	0.02136286	[0.014-0.028] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.5102	NA	0.02136286
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p21.1	6	42229969	TRERF1	TRERF1	NA	NA	ENSG00000124496	NA	NA	rs61612642-T	rs61612642	0	61612642	intron_variant	FALSE	0.1662	4e-9	8.397940008672037	NA	0.02859207	[0.019-0.038] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.1662	NA	0.02859207
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p21.1	6	42318077	TRERF1	TRERF1	NA	NA	ENSG00000124496	NA	NA	rs4714599-C	rs4714599	0	4714599	intron_variant	FALSE	0.3089	9e-10	9.045757490560675	NA	0.02427585	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.3089	NA	0.02427585
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6p21.1	6	42548053	intergenic	TRERF1 - UBR2	ENSG00000124496	ENSG00000024048	NA	96002	15976	rs16895831-T	rs16895831	0	16895831	regulatory_region_variant	TRUE	0.2032	1e-13	13	NA	0.03316487	[0.024-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.2032	NA	0.03316487
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6q14.3	6	87112110	intergenic	CGA - RCN1P1	ENSG00000135346	ENSG00000215477	NA	17004	9583	rs67614146-A	rs67614146	0	67614146	intergenic_variant	TRUE	0.4869	5e-15	14.301029995663981	NA	0.02877099	[0.022-0.036] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.4869	NA	0.02877099
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	10q24.31	10	100359243	SCD	SCD	NA	NA	ENSG00000099194	NA	NA	rs55710213-T	rs55710213	0	55710213	intron_variant	FALSE	0.361	2e-9	8.698970004336019	NA	0.0222364	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.361	NA	0.0222364
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	10q26.13	10	124694794	FAM53B, RP11-12J10.3	FAM53B	NA	NA	ENSG00000189319	NA	NA	rs4450131-C	rs4450131	0	4450131	intron_variant	FALSE	0.5249	5e-10	9.301029995663981	NA	0.02199829	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.5249	NA	0.02199829
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	11p15.5	11	2301968	C11orf21	C11orf21	NA	NA	ENSG00000110665	NA	NA	rs734095-G	rs734095	0	734095	intron_variant	FALSE	0.1138	1e-13	13	NA	0.0410548	[0.03-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.1138	NA	0.0410548
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	11q13.4	11	73232438	P2RY2	P2RY2	NA	NA	ENSG00000175591	NA	NA	rs149467613-A	rs149467613	0	149467613	intron_variant	FALSE	0.0488	5e-27	26.30102999566398	NA	0.0905766	[0.074-0.107] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.0488	NA	0.0905766
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	11q24.3	11	128315955	intergenic	LINC02098 - ETS1	ENSG00000272575	ENSG00000134954	NA	74514	142806	rs10893844-C	rs10893844	0	10893844	regulatory_region_variant	TRUE	0.504	2e-11	10.698970004336019	NA	0.02332743	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.504	NA	0.02332743
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	12q14.3	12	66327321	HELB	HELB	NA	NA	ENSG00000127311	NA	NA	rs1691799-G	rs1691799	0	1691799	intron_variant	FALSE	0.4595	1e-14	14	NA	0.02722433	[0.02-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.4595	NA	0.02722433
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	12q24.12	12	111621753	intergenic	ATXN2-AS - BRAP	ENSG00000258099	ENSG00000089234	NA	21497	20393	rs11065979-T	rs11065979	0	11065979	intergenic_variant	TRUE	0.4389	1e-12	12	NA	0.02509587	[0.018-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.4389	NA	0.02509587
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	14q11.2	14	23123308	CEBPE	CEBPE - SLC7A8	ENSG00000092067	ENSG00000092068	NA	4053	1987	rs28479481-T	rs28479481	0	28479481	intergenic_variant	TRUE	0.0616	3e-22	21.522878745280337	NA	0.07067546	[0.056-0.085] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.0616	NA	0.07067546
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	15q26.1	15	90466252	IQGAP1	IQGAP1	NA	NA	ENSG00000140575	NA	NA	rs2074585-A	rs2074585	0	2074585	intron_variant	FALSE	0.5143	2e-16	15.698970004336019	NA	0.02881194	[0.022-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.5143	NA	0.02881194
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	16q24.2	16	87888430	CA5A	CA5A	NA	NA	ENSG00000174990	NA	NA	rs8056952-G	rs8056952	0	8056952	intron_variant	FALSE	0.3504	2e-10	9.698970004336019	NA	0.02438734	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.3504	NA	0.02438734
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	16q24.2	16	88451314	ZFPM1	ZNF469 - ZFPM1	ENSG00000225614	ENSG00000179588	NA	10557	1966	rs12447180-C	rs12447180	0	12447180	intergenic_variant	TRUE	0.3224	5e-18	17.30102999566398	NA	0.03246716	[0.025-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.3224	NA	0.03246716
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	17q22	17	58262233	LPO	LPO	NA	NA	ENSG00000167419	NA	NA	rs546552332-C	rs546552332	0	546552332	intron_variant	FALSE	0.0039	1e-10	10	NA	0.1915609	[0.13-0.25] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.0039	NA	0.1915609
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	17q23.1	17	59833869	VMP1	VMP1	NA	NA	ENSG00000062716	NA	NA	rs1292061-G	rs1292061	0	1292061	intron_variant	FALSE	0.5556	9e-10	9.045757490560675	NA	0.02146964	[0.015-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.5556	NA	0.02146964
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	19p13.3	19	836144	PRTN3	AZU1 - PRTN3	ENSG00000172232	ENSG00000196415	NA	4126	4855	rs56757486-A	rs56757486	0	56757486	intergenic_variant	TRUE	0.2526	6e-13	12.221848749616356	NA	0.03000519	[0.022-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.2526	NA	0.03000519
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	19p13.3	19	5839602	FUT6	FUT6	NA	NA	ENSG00000156413	NA	NA	rs778798-C	rs778798	0	778798	5_prime_UTR_variant	FALSE	0.7315	2e-12	11.698970004336019	NA	0.02817483	[0.02-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.7315	NA	0.02817483
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	19p13.11	19	19357128	MAU2	MAU2	NA	NA	ENSG00000129933	NA	NA	rs2285627-C	rs2285627	0	2285627	3_prime_UTR_variant	FALSE	0.6675	1e-9	9	NA	0.02261553	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.6675	NA	0.02261553
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	19q13.11	19	33263765	intergenic	SLC7A10 - CEBPA	ENSG00000130876	ENSG00000245848	NA	37915	36169	rs34610286-T	rs34610286	0	34610286	TF_binding_site_variant	TRUE	0.099	3e-10	9.522878745280337	NA	0.03761852	[0.026-0.049] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.099	NA	0.03761852
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	19q13.11	19	33264533	intergenic	SLC7A10 - CEBPA	ENSG00000130876	ENSG00000245848	NA	38683	35401	rs34129834-C	rs34129834	0	34129834	intergenic_variant	TRUE	0.2262	5e-39	38.30102999566398	NA	0.05546477	[0.047-0.064] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.2262	NA	0.05546477
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	19q13.2	19	38434439	RYR1	RYR1	NA	NA	ENSG00000196218	NA	NA	rs71356805-C	rs71356805	0	71356805	intron_variant	FALSE	0.0277	4e-22	21.397940008672037	NA	0.1033711	[0.082-0.124] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.0277	NA	0.1033711
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	20p13	20	1950355	RP4-684O24.5	PDYN-AS1	NA	NA	ENSG00000233896	NA	NA	rs6045612-T	rs6045612	0	6045612	intron_variant	FALSE	0.2625	2e-9	8.698970004336019	NA	0.02377003	[0.016-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.2625	NA	0.02377003
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	20q11.21	20	32668027	C20orf203	C20orf203	NA	NA	ENSG00000198547	NA	NA	rs6058796-T	rs6058796	0	6058796	intron_variant	FALSE	0.1451	5e-16	15.301029995663981	NA	0.04033086	[0.031-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.1451	NA	0.04033086
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	NA	NA	NA	PABPC1L	NA	NA	NA	NA	NA	NA	chr20:43537200-C	chr20:43537200	0	NA	NA	TRUE	0.275	7e-9	8.154901959985743	NA	0.02255287	[0.015-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.275	NA	0.02255287
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	21q22.12	21	35420326	RUNX1	RUNX1	NA	NA	ENSG00000159216	NA	NA	rs150498232-G	rs150498232	0	150498232	intron_variant	FALSE	0.0259	3e-14	13.522878745280337	NA	0.09096069	[0.068-0.114] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.0259	NA	0.09096069
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	19q13.11	19	33269055	intergenic	SLC7A10 - CEBPA	ENSG00000130876	ENSG00000245848	NA	43205	30879	rs10401672-T	rs10401672	0	10401672	intergenic_variant	TRUE	0.3709	2e-42	41.69897000433602	NA	0.0499181	[0.043-0.057] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.3709	NA	0.0499181
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	20q11.21	20	32585560	RP11-410N8.1	NOL4L-DT	NA	NA	ENSG00000204393	NA	NA	rs67696533-A	rs67696533	0	67696533	intron_variant	FALSE	0.3119	5e-11	10.301029995663981	NA	0.02494351	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.3119	NA	0.02494351
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6q21	6	109295876	CCDC162P	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs9487051-G	rs9487051	0	9487051	intron_variant	FALSE	0.4549	3e-19	18.522878745280337	NA	0.0326085	[0.025-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4549	NA	0.0326085
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	13q14.3	13	50814824	DLEU7-AS1, DLEU7	DLEU7, DLEU1	NA	NA	ENSG00000186047, ENSG00000176124	NA	NA	rs9535495-T	rs9535495	0	9535495	intron_variant	FALSE	0.5569	3e-11	10.522878745280337	NA	0.02426266	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.5569	NA	0.02426266
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	11q23.3	11	116778201	ZNF259	ZPR1	NA	NA	ENSG00000109917	NA	NA	rs964184-C	rs964184	0	964184	3_prime_UTR_variant	FALSE	0.8665	5e-13	12.301029995663981	NA	0.03808436	[0.028-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.8665	NA	0.03808436
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	3p21.31	3	49345492	USP4	USP4 - GPX1	ENSG00000114316	ENSG00000233276	NA	4780	11684	rs9818758-A	rs9818758	0	9818758	regulatory_region_variant	TRUE	0.1712	2e-49	48.69897000433602	NA	0.07038824	[0.061-0.08] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1712	NA	0.07038824
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	7q31.2	7	116560038	CAV1	CAV1	NA	NA	ENSG00000105974	NA	NA	rs9920-C	rs9920	0	9920	3_prime_UTR_variant	FALSE	0.1051	1e-24	24	NA	0.06028422	[0.049-0.072] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1051	NA	0.06028422
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	16q24.3	16	89873521	TCF25	SPIRE2 - TCF25	ENSG00000204991	ENSG00000141002	NA	2202	49	rs9939914-C	rs9939914	0	9939914	regulatory_region_variant	TRUE	0.2539	1e-14	14	NA	0.0322975	[0.024-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2539	NA	0.0322975
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	2p22.3	2	32338357	intergenic	YIPF4 - BIRC6	ENSG00000119820	ENSG00000115760	NA	21763	18671	rs11678584-T	rs11678584	0	11678584	intergenic_variant	TRUE	0.1359	2e-11	10.698970004336019	NA	0.03585364	[0.025-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1359	NA	0.03585364
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	2p16.3	2	48464072	PPP1R21	PPP1R21	NA	NA	ENSG00000162869	NA	NA	rs11678825-T	rs11678825	0	11678825	intron_variant	FALSE	0.127	8e-10	9.096910013008056	NA	0.03310021	[0.023-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.127	NA	0.03310021
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	12q24.31	12	122464360	intergenic	CLIP1 - ZCCHC8	ENSG00000130779	ENSG00000033030	NA	41691	7239	rs116896792-C	rs116896792	0	116896792	TF_binding_site_variant	TRUE	0.0919	8e-9	8.096910013008056	NA	0.03579389	[0.024-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0919	NA	0.03579389
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	4q31.21	4	144104973	RP11-673E1.4, GYPB	GYPB - GYPA	ENSG00000250361	ENSG00000170180	NA	85593	4330	rs11735662-T	rs11735662	0	11735662	intron_variant	TRUE	0.0344	1e-19	19	NA	0.08937307	[0.07-0.109] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0344	NA	0.08937307
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	20q13.31	20	57169375	BMP7	BMP7	NA	NA	ENSG00000101144	NA	NA	rs117553902-T	rs117553902	0	117553902	3_prime_UTR_variant	FALSE	0.0024	4e-20	19.397940008672037	NA	0.372492	[0.29-0.45] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0024	NA	0.372492
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1p36.32	1	3774964	SMIM1	SMIM1	NA	NA	ENSG00000235169	NA	NA	rs1175550-G	rs1175550	0	1175550	intron_variant	FALSE	0.2319	3e-34	33.52287874528034	NA	0.05187558	[0.044-0.06] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2319	NA	0.05187558
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	16p13.3	16	168533	HBA2, Z84721.4	HBM - HBAP1	ENSG00000206177	ENSG00000225323	NA	1769	146	rs1203833-C	rs1203833	0	1203833	intergenic_variant	TRUE	0.1788	1e-30	30	NA	0.0543483	[0.045-0.064] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1788	NA	0.0543483
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	15q15.1	15	40014133	EIF2AK4	EIF2AK4	NA	NA	ENSG00000128829	NA	NA	rs12050884-A	rs12050884	0	12050884	intron_variant	FALSE	0.2067	1e-10	10	NA	0.02857949	[0.02-0.037] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2067	NA	0.02857949
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	22q12.2	22	29237245	EMID1	EMID1	NA	NA	ENSG00000186998	NA	NA	rs12158292-C	rs12158292	0	12158292	intron_variant	FALSE	0.5648	1e-10	10	NA	0.02378699	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.5648	NA	0.02378699
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6q21	6	110438805	SLC22A16	SLC22A16	NA	NA	ENSG00000004809	NA	NA	rs12210538-G	rs12210538	0	12210538	missense_variant	FALSE	0.2371	8e-17	16.096910013008056	NA	0.03513863	[0.027-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2371	NA	0.03513863
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	11p15.2	11	16591389	SOX6	SOX6	NA	NA	ENSG00000110693	NA	NA	rs12365482-T	rs12365482	0	12365482	intron_variant	FALSE	0.2893	8e-23	22.096910013008056	NA	0.03904242	[0.031-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2893	NA	0.03904242
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	8p21.2	8	23542024	SLC25A37	SLC25A37	NA	NA	ENSG00000147454	NA	NA	rs12549025-G	rs12549025	0	12549025	intron_variant	FALSE	0.1638	3e-10	9.522878745280337	NA	0.03055117	[0.021-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1638	NA	0.03055117
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	8p11.21	8	41796022	ANK1	ANK1	NA	NA	ENSG00000029534	NA	NA	rs12550646-G	rs12550646	0	12550646	intron_variant	FALSE	0.295	3e-40	39.52287874528034	NA	0.05217984	[0.044-0.06] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.295	NA	0.05217984
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	19p13.3	19	898288	R3HDM4	R3HDM4	NA	NA	ENSG00000198858	NA	NA	rs12985393-T	rs12985393	0	12985393	intron_variant	FALSE	0.2964	1e-10	10	NA	0.02618045	[0.018-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2964	NA	0.02618045
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	20p13	20	4151717	SMOX	SMOX	NA	NA	ENSG00000088826	NA	NA	rs13043612-G	rs13043612	0	13043612	intron_variant	FALSE	0.3348	2e-62	61.69897000433602	NA	0.06383781	[0.056-0.071] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.3348	NA	0.06383781
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	4q31.21	4	143989463	RP11-673E1.4	GYPE - GYPB	ENSG00000197465	ENSG00000250361	NA	83900	6641	rs13101482-A	rs13101482	0	13101482	intron_variant	TRUE	0.6882	1e-46	46	NA	0.05585973	[0.048-0.063] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.6882	NA	0.05585973
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1q44	1	247875992	TRIM58	TRIM58	NA	NA	ENSG00000162722	NA	NA	rs1339847-A	rs1339847	0	1339847	missense_variant	FALSE	0.1095	1e-208	208	NA	0.176416	[0.17-0.19] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1095	NA	0.176416
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	3p14.3	3	56815721	ARHGEF3	ARHGEF3	NA	NA	ENSG00000163947	NA	NA	rs1354034-C	rs1354034	0	1354034	intron_variant	FALSE	0.5988	4e-10	9.397940008672037	NA	0.02278417	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.5988	NA	0.02278417
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	7q22.1	7	101856650	CUX1	CUX1	NA	NA	ENSG00000257923	NA	NA	rs139141690-A	rs139141690	0	139141690	intron_variant	FALSE	0.0053	2e-9	8.698970004336019	NA	0.1535754	[0.1-0.2] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0053	NA	0.1535754
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	5q33.2	5	154647656	intergenic	MIR3141 - MIR1303	ENSG00000264760	ENSG00000221552	NA	51584	38120	rs74417235-G	rs74417235	0	74417235	intergenic_variant	TRUE	0.0952	7e-48	47.15490195998574	NA	0.08978864	[0.078-0.102] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0952	NA	0.08978864
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	17q12	17	35596533	AP2B1	AP2B1	NA	NA	ENSG00000006125	NA	NA	rs74505413-G	rs74505413	0	74505413	intron_variant	FALSE	0.0428	2e-81	80.69897000433602	NA	0.1700208	[0.15-0.19] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0428	NA	0.1700208
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	8q24.3	8	141218810	SLC45A4	SLC45A4	NA	NA	ENSG00000022567	NA	NA	rs753778-A	rs753778	0	753778	missense_variant	FALSE	0.2935	3e-9	8.522878745280337	NA	0.02332289	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2935	NA	0.02332289
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	13q34	13	109759295	IRS2	IRS2	NA	NA	ENSG00000185950	NA	NA	rs754205-C	rs754205	0	754205	intron_variant	FALSE	0.3804	5e-10	9.301029995663981	NA	0.02318425	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.3804	NA	0.02318425
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	4q25	4	109990411	EGF	EGF	NA	NA	ENSG00000138798	NA	NA	rs7692976-G	rs7692976	0	7692976	intron_variant	FALSE	0.4041	5e-10	9.301029995663981	NA	0.02296516	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4041	NA	0.02296516
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	5q11.2	5	54351327	LINC01033	LINC01033	NA	NA	ENSG00000249069	NA	NA	rs7710385-A	rs7710385	0	7710385	intron_variant	FALSE	0.1517	2e-12	11.698970004336019	NA	0.03543344	[0.026-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1517	NA	0.03543344
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1p36.11	1	23839150	HMGCL	HMGCL - FUCA1	ENSG00000117305	ENSG00000179163	NA	530	5927	rs773011284-A	rs773011284	1	58094828	regulatory_region_variant	TRUE	0.4242	3e-11	10.522878745280337	NA	0.02415589	[0.017-0.031] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4242	NA	0.02415589
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	5q11.2	5	58021714	intergenic	NA - LINC02101	NA	ENSG00000248132	NA	NA	85917	rs7736576-C	rs7736576	0	7736576	regulatory_region_variant	TRUE	0.2197	3e-9	8.522878745280337	NA	0.0256351	[0.017-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2197	NA	0.0256351
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	1p32.2	1	56158423	RP1-158P9.1	NA - RPSAP20	NA	ENSG00000229871	NA	NA	49144	rs778387-G	rs778387	0	778387	intron_variant	TRUE	0.404	1e-25	25	NA	0.0396332	[0.032-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.404	NA	0.0396332
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	7q31.32	7	123778439	intergenic	WASL-DT - RNU6-11P	ENSG00000272686	ENSG00000201104	NA	27273	12166	rs77972171-T	rs77972171	0	77972171	intergenic_variant	TRUE	0.0786	7e-9	8.154901959985743	NA	0.03871022	[0.026-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0786	NA	0.03871022
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	15q22.2	15	62505765	TLN2	TLN2	NA	NA	ENSG00000171914	NA	NA	rs780142-G	rs780142	0	780142	intron_variant	FALSE	0.2736	1e-15	15	NA	0.03215649	[0.024-0.04] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2736	NA	0.03215649
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	10q24.33	10	103107201	NT5C2	NT5C2	NA	NA	ENSG00000076685	NA	NA	rs7896547-G	rs7896547	0	7896547	intron_variant	FALSE	0.3906	3e-55	54.52287874528034	NA	0.05746989	[0.05-0.065] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.3906	NA	0.05746989
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	10q11.21	10	45458319	NR	MARCHF8, MARCHF8	NA	NA	ENSG00000165406, ENSG00000278545	NA	NA	rs7908745-G	rs7908745	0	7908745	missense_variant	FALSE	0.3143	1e-19	19	NA	0.03506293	[0.028-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.3143	NA	0.03506293
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6p22.2	6	26098246	HFE	HFE	NA	NA	ENSG00000010704	NA	NA	rs79220007-C	rs79220007	0	79220007	3_prime_UTR_variant	FALSE	0.0768	5e-88	87.30102999566398	NA	0.1340241	[0.12-0.15] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0768	NA	0.1340241
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	14q11.2	14	23025068	PSMB5	PSMB5	NA	NA	ENSG00000100804	NA	NA	rs8013143-G	rs8013143	0	8013143	intron_variant	FALSE	0.2794	4e-39	38.39794000867204	NA	0.05232083	[0.044-0.06] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2794	NA	0.05232083
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	17q21.2	17	41844756	KLHL10	KLHL10	NA	NA	ENSG00000161594	NA	NA	rs8068544-C	rs8068544	0	8068544	intron_variant	FALSE	0.9171	6e-13	12.221848749616356	NA	0.04684634	[0.034-0.06] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.9171	NA	0.04684634
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	17q12	17	35537752	SLFN12L	SLFN12L	NA	NA	ENSG00000286065	NA	NA	rs8082605-T	rs8082605	0	8082605	non_coding_transcript_exon_variant	FALSE	0.0395	5e-53	52.30102999566398	NA	0.1411431	[0.12-0.16] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.0395	NA	0.1411431
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6p22.3	6	16282288	GMPR	GMPR	NA	NA	ENSG00000137198	NA	NA	rs869167739-A	rs869167739	1	11298204	intron_variant	FALSE	0.2628	6e-16	15.221848749616356	NA	0.03306031	[0.025-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2628	NA	0.03306031
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	5q35.2	5	173860848	intergenic	LINC01485 - CPEB4	ENSG00000254211	ENSG00000113742	NA	51809	27501	rs875741-A	rs875741	0	875741	intergenic_variant	TRUE	0.4063	2e-48	47.69897000433602	NA	0.05342549	[0.046-0.061] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4063	NA	0.05342549
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	2p23.3	2	24023809	MFSD2B	MFSD2B	NA	NA	ENSG00000205639	NA	NA	rs925228-G	rs925228	0	925228	intron_variant	FALSE	0.7643	9e-20	19.045757490560675	NA	0.0384053	[0.03-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.7643	NA	0.0384053
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6p21.1	6	41957421	CCND3	CCND3	NA	NA	ENSG00000112576	NA	NA	rs9349205-A	rs9349205	0	9349205	intron_variant	FALSE	0.2513	8e-18	17.096910013008056	NA	0.03545363	[0.027-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2513	NA	0.03545363
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6p12.3	6	47480600	CD2AP	CD2AP	NA	NA	ENSG00000198087	NA	NA	rs9367279-G	rs9367279	0	9367279	intron_variant	FALSE	0.2747	2e-11	10.698970004336019	NA	0.02681282	[0.019-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.2747	NA	0.02681282
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6q23.3	6	134959381	HBS1L	ALDH8A1 - HBS1L	ENSG00000118514	ENSG00000112339	NA	9266	997	rs9376072-C	rs9376072	0	9376072	intergenic_variant	TRUE	0.4336	9e-35	34.045757490560675	NA	0.04447491	[0.037-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.4336	NA	0.04447491
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	9q21.13	9	74369637	RP11-171A24.2	NA	NA	NA	NA	NA	NA	rs9411103-G	rs9411103	0	9411103	intergenic_variant	TRUE	0.3313	4e-10	9.397940008672037	NA	0.0240727	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.3313	NA	0.0240727
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Reticulocyte fraction of red cells	170,690 European ancestry individuals	NA	6q21	6	108641439	FOXO3	FOXO3	NA	NA	ENSG00000118689	NA	NA	rs9480866-T	rs9480866	0	9480866	intron_variant	FALSE	0.1565	2e-9	8.698970004336019	NA	0.02957763	[0.02-0.039] unit decrease	Affymetrix [~ 2500000] (imputed)	N	reticulocyte count	http://www.ebi.ac.uk/efo/EFO_0007986	GCST004619	Genome-wide genotyping array	0.1565	NA	0.02957763
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78642209	CHRNB4	CHRNB4	NA	NA	ENSG00000117971	NA	NA	rs3813567-A	rs3813567	0	3813567	intron_variant	FALSE	0.808	1e-7	7	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.808	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78453001	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2656071-A	rs2656071	0	2656071	intron_variant	FALSE	0.811	2e-7	6.698970004336019	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.811	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78733659	Intergenic	CHRNB4 - ADAMTS7	ENSG00000117971	ENSG00000136378	NA	5905	25547	rs3894347-A	rs3894347	0	3894347	splice_region_variant	TRUE	0.362	4e-7	6.3979400086720375	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.362	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128169332	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs34409786-A	rs34409786	0	34409786	intron_variant	FALSE	0.839	9e-7	6.045757490560675	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.839	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128305133	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2811392-A	rs2811392	0	2811392	intron_variant	FALSE	0.836	1e-6	6	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.836	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128243914	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955085-A	rs2955085	0	2955085	intron_variant	FALSE	0.84	1e-6	6	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.84	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128244033	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2999072-C	rs2999072	0	2999072	intron_variant	FALSE	0.84	1e-6	6	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.84	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128244867	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955088-T	rs2955088	0	2955088	intron_variant	FALSE	0.84	1e-6	6	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.84	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128218971	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2955130-A	rs2955130	0	2955130	intron_variant	FALSE	0.84	1e-6	6	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.84	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128237865	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2999080-A	rs2999080	0	2999080	intron_variant	FALSE	0.84	1e-6	6	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.84	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128235591	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2999083-T	rs2999083	0	2999083	intron_variant	FALSE	0.84	1e-6	6	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.84	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128201232	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2811486-A	rs2811486	0	2811486	intron_variant	FALSE	0.839	1e-6	6	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.839	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	9p24.3	9	306734	DOCK8	DOCK8	NA	NA	ENSG00000107099	NA	NA	rs62533402-T	rs62533402	0	62533402	intron_variant	FALSE	0.84	3e-6	5.522878745280337	NA	0.059	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.84	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78487042	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs12904234-T	rs12904234	0	12904234	intron_variant	FALSE	0.566	9e-11	10.045757490560675	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.566	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	9q34.2	9	133640119	DBH	DBH	NA	NA	ENSG00000123454	NA	NA	rs1108581-A	rs1108581	0	1108581	intron_variant	FALSE	0.292	9e-9	8.045757490560675	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.292	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144349803	Intergenic	NA	NA	NA	NA	NA	NA	rs6834183-T	rs6834183	0	6834183	intron_variant	TRUE	0.724	1e-8	8	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.724	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q31.21	4	144357685	Intergenic	NA	NA	NA	NA	NA	NA	rs17766287-T	rs17766287	0	17766287	intron_variant	TRUE	0.275	1e-8	8	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.275	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78444251	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2568488-A	rs2568488	0	2568488	intron_variant	FALSE	0.811	2e-7	6.698970004336019	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.811	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78459772	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs2568485-T	rs2568485	0	2568485	intron_variant	FALSE	0.811	2e-7	6.698970004336019	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.811	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q22.2	11	102858443	Intergenic	MMP3 - MMP12	ENSG00000149968	ENSG00000262406	NA	14834	4293	rs654600-A	rs654600	0	654600	intergenic_variant	TRUE	0.793	2e-7	6.698970004336019	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.793	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78482334	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs10851906-A	rs10851906	0	10851906	intron_variant	FALSE	0.811	2e-7	6.698970004336019	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.811	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78439466	IREB2	IREB2	NA	NA	ENSG00000136381	NA	NA	rs924840-A	rs924840	0	924840	intron_variant	FALSE	0.811	2e-7	6.698970004336019	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.811	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q25.1	15	78422219	Intergenic	CRABP1 - IREB2	ENSG00000166426	ENSG00000136381	NA	73994	15212	rs2869032-T	rs2869032	0	2869032	regulatory_region_variant	TRUE	0.819	3e-7	6.522878745280337	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.819	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128269024	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2811400-A	rs2811400	0	2811400	intron_variant	FALSE	0.84	1e-6	6	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.84	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q21.3	3	128272334	EEFSEC	EEFSEC	NA	NA	ENSG00000132394	NA	NA	rs2811414-C	rs2811414	0	2811414	intron_variant	FALSE	0.84	1e-6	6	NA	0.058	NR unit decrease	Illumina [NR] (imputed)	N	forced expiratory volume, response to bronchodilator	http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366	GCST003262	Genome-wide genotyping array	0.84	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6q15	6	90246690	BACH2	BACH2	NA	NA	ENSG00000112182	NA	NA	rs62408225-G	rs62408225	0	62408225	intron_variant	FALSE	0.3513	2e-19	18.69897000433602	NA	0.03360406	[0.026-0.041] unit decrease	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.3513	NA	0.03360406
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6q21	6	107125336	intergenic	BEND3 - RNU6-1299P	ENSG00000178409	ENSG00000252125	NA	9821	7735	rs6902010-G	rs6902010	0	6902010	regulatory_region_variant	TRUE	0.5331	1e-17	17	NA	0.03163848	[0.024-0.039] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.5331	NA	0.03163848
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Eosinophil percentage of granulocytes	170,536 European ancestry individuals	NA	6q23.3	6	135085045	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs9402682-T	rs9402682	0	9402682	intron_variant	FALSE	0.2409	9e-17	16.045757490560675	NA	0.03517155	[0.027-0.043] unit increase	Affymetrix [~ 2500000] (imputed)	N	eosinophil percentage of granulocytes	http://www.ebi.ac.uk/efo/EFO_0007996	GCST004617	Genome-wide genotyping array	0.2409	NA	0.03517155
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	1p36.23	1	8857340	ENO1	RERE - ENO1	ENSG00000142599	ENSG00000074800	NA	8419	3660	rs79565040-TTA	rs79565040	1	59246144	regulatory_region_variant	TRUE	0.5023	1e-9	9	NA	0.02121351	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.5023	NA	0.02121351
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	1q23.2	1	159205564	DARC	ACKR1, CADM3-AS1	NA	NA	ENSG00000213088, ENSG00000225670	NA	NA	rs12075-A	rs12075	0	12075	missense_variant	FALSE	0.58	9e-23	22.045757490560675	NA	0.03469341	[0.028-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.58	NA	0.03469341
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	1q32.1	1	205175235	DSTYK	DSTYK	NA	NA	ENSG00000133059	NA	NA	rs11579220-T	rs11579220	0	11579220	intron_variant	FALSE	0.4382	1e-14	14	NA	0.02707159	[0.02-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.4382	NA	0.02707159
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	1q32.3	1	212385055	TMEM206	PACC1	NA	NA	ENSG00000065600	NA	NA	rs792448-A	rs792448	0	792448	intron_variant	FALSE	0.3442	2e-14	13.698970004336019	NA	0.02823878	[0.021-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.3442	NA	0.02823878
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	1q42.3	1	235939586	RP5-940F7.2	RNU6-968P - LINC02768	ENSG00000206803	ENSG00000229291	NA	24065	18293	rs6701752-A	rs6701752	0	6701752	intergenic_variant	TRUE	0.8923	1e-41	41	NA	0.07659441	[0.065-0.088] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.8923	NA	0.07659441
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	2q13	2	111410354	MIR4435-1HG	MIR4435-2HG	NA	NA	ENSG00000172965	NA	NA	rs62160676-C	rs62160676	0	62160676	intron_variant	FALSE	0.2975	4e-10	9.397940008672037	NA	0.02409079	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.2975	NA	0.02409079
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	2q22.3	2	144567410	AC010090.1	LINC01412	NA	NA	ENSG00000232606	NA	NA	rs16823866-C	rs16823866	0	16823866	intron_variant	FALSE	0.1951	6e-11	10.221848749616356	NA	0.02902272	[0.02-0.038] unit decrease	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.1951	NA	0.02902272
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	White blood cell count (basophil)	171,846 European ancestry individuals	NA	2q22.3	2	147841722	ACVR2A	NA - ACVR2A	NA	ENSG00000121989	NA	NA	2795	rs70992176-C	rs70992176	0	70992176	intergenic_variant	TRUE	0.2415	2e-10	9.698970004336019	NA	0.02610869	[0.018-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	basophil count	http://www.ebi.ac.uk/efo/EFO_0005090	GCST004618	Genome-wide genotyping array	0.2415	NA	0.02610869
2019-08-12	27903959	Lv H	2017-01-31	Oncotarget	www.ncbi.nlm.nih.gov/pubmed/27903959	Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.	Core binding factor acute myeloid leukemia	175 European ancestry cases, 218 European ancestry controls	NA	1p34.3	1	37683093	NR	C1orf109; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs684260-G; rs497705-C; rs11264091-G; rs3790623-G; rs658024-A; rs510208-T; rs11264087-C; rs661460-A; rs768659-A; rs12139097-T; rs12119598-C; rs10908369-G; rs589927-G; rs3762352-C; rs557897-G; rs507667-A	rs684260; rs497705; rs11264091; rs3790623; rs658024; rs510208; rs11264087; rs661460; rs768659; rs12139097; rs12119598; rs10908369; rs589927; rs3762352; rs557897; rs507667	0	NA	3_prime_UTR_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; intergenic_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; 3_prime_UTR_variant; intron_variant	NA	0.019	3e-20	19.522878745280337	NA	NA	NA	Affymetrix [734624]	N	acute myeloid leukemia	http://www.ebi.ac.uk/efo/EFO_0000222	GCST008413	Genome-wide genotyping array	0.019	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6p21.33	6	31354590	HLA-B	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B, HLA-B	NA	NA	ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000232126, ENSG00000224608, ENSG00000206450	NA	NA	rs3819299-G	rs3819299	0	3819299	non_coding_transcript_exon_variant	FALSE	0.0557	2e-28	27.69897000433602	NA	0.08786675	[0.072-0.103] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0557	NA	0.08786675
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6p21.33	6	31374110	FGFR3P1	RNU6-283P - FGFR3P1	ENSG00000201658	ENSG00000230994	NA	3870	3309	rs2523515-A	rs2523515	0	2523515	intron_variant	TRUE	0.3451	6e-13	12.221848749616356	NA	0.02824211	[0.021-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3451	NA	0.02824211
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6p21.33	6	31493781	MICB	MICB-DT	NA	NA	ENSG00000286940	NA	NA	rs3094006-C	rs3094006	0	3094006	intron_variant	FALSE	0.726	1e-12	12	NA	0.02938566	[0.021-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.726	NA	0.02938566
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6p21.31	6	33579060	BAK1	BAK1, GGNBP1	NA	NA	ENSG00000030110, ENSG00000204188	NA	NA	rs210142-C	rs210142	0	210142	intron_variant	FALSE	0.7016	3e-171	170.52287874528034	NA	0.1113763	[0.1-0.12] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.7016	NA	0.1113763
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6p21.31	6	33584930	GGNBP1	GGNBP1	NA	NA	ENSG00000204188	NA	NA	rs75080135-C	rs75080135	0	75080135	intron_variant	FALSE	0.1773	7e-116	115.15490195998575	NA	0.1096288	[0.1-0.12] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1773	NA	0.1096288
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6p21.31	6	33750641	IP6K3	IP6K3 - LEMD2	ENSG00000161896	ENSG00000161904	NA	3736	20561	rs4713675-T	rs4713675	0	4713675	regulatory_region_variant	TRUE	0.5449	3e-67	66.52287874528034	NA	0.06381666	[0.057-0.071] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5449	NA	0.06381666
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6p21.31	6	34801988	UHRF1BP1	UHRF1BP1	NA	NA	ENSG00000065060	NA	NA	rs4472337-T	rs4472337	0	4472337	intron_variant	FALSE	0.1616	2e-17	16.69897000433602	NA	0.04212671	[0.032-0.052] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1616	NA	0.04212671
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6p21.2	6	37342422	intergenic	TBC1D22B - RNF8	ENSG00000065491	ENSG00000112130	NA	9452	11557	rs570442571-AT	rs570442571	1	376444936	intergenic_variant	TRUE	0.6637	7e-12	11.154901959985743	NA	0.02660747	[0.019-0.034] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6637	NA	0.02660747
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6p21.1	6	43385160	intergenic	ZNF318 - ABCC10	ENSG00000171467	ENSG00000124574	NA	15513	42206	rs6919440-A	rs6919440	0	6919440	intron_variant	TRUE	0.5671	3e-9	8.522878745280337	NA	0.02175354	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5671	NA	0.02175354
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6p12.2	6	52791371	GSTA1	GSTA1	NA	NA	ENSG00000243955	NA	NA	rs2894802-G	rs2894802	0	2894802	3_prime_UTR_variant	FALSE	0.5733	4e-16	15.397940008672037	NA	0.02995429	[0.023-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5733	NA	0.02995429
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6q21	6	109271126	C6orf183	CCDC162P	NA	NA	ENSG00000203799	NA	NA	rs6910696-T	rs6910696	0	6910696	intron_variant	FALSE	0.4782	8e-14	13.096910013008056	NA	0.02728362	[0.02-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4782	NA	0.02728362
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6q22.31	6	122457805	SERINC1	SERINC1	NA	NA	ENSG00000111897	NA	NA	rs149291347-CATAT	rs149291347	0	149291347	intron_variant	FALSE	0.5376	3e-10	9.522878745280337	NA	0.02307726	[0.016-0.03] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5376	NA	0.02307726
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6q23.1	6	130821850	intergenic	NA - SMLR1	NA	ENSG00000256162	NA	NA	5556	rs141573810-G	rs141573810	1	35621888	intergenic_variant	TRUE	0.5282	3e-9	8.522878745280337	NA	0.02205216	[0.015-0.029] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5282	NA	0.02205216
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6q23.3	6	134730181	intergenic	NA	NA	NA	NA	NA	NA	rs71736125-T	rs71736125	0	71736125	regulatory_region_variant	TRUE	0.2082	1e-21	21	NA	0.04309661	[0.034-0.052] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2082	NA	0.04309661
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6q23.3	6	134976524	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs4580893-A	rs4580893	0	4580893	intron_variant	FALSE	0.3799	4e-27	26.397940008672037	NA	0.04043883	[0.033-0.048] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3799	NA	0.04043883
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6q23.3	6	135083984	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs1331308-C	rs1331308	0	1331308	intron_variant	FALSE	0.4958	1e-23	23	NA	0.03678186	[0.03-0.044] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4958	NA	0.03678186
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6q23.3	6	135097778	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs7776054-G	rs7776054	0	7776054	intron_variant	FALSE	0.2605	5e-233	232.30102999566398	NA	0.1357089	[0.13-0.14] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2605	NA	0.1357089
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	6q26	6	164042323	intergenic	NA	NA	NA	NA	NA	NA	rs4709819-A	rs4709819	0	4709819	intergenic_variant	TRUE	0.4063	2e-29	28.69897000433602	NA	0.04207929	[0.035-0.049] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4063	NA	0.04207929
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7p22.2	7	2826844	GNA12	GNA12	NA	NA	ENSG00000146535	NA	NA	rs1182196-G	rs1182196	0	1182196	intron_variant	FALSE	0.4249	3e-14	13.522878745280337	NA	0.02813604	[0.021-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4249	NA	0.02813604
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7p21.1	7	18160840	HDAC9	HDAC9	NA	NA	ENSG00000048052	NA	NA	rs1019068-C	rs1019068	0	1019068	intron_variant	FALSE	0.2118	2e-14	13.698970004336019	NA	0.03433184	[0.026-0.043] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2118	NA	0.03433184
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7p13	7	44847477	H2AFV	H2AZ2	NA	NA	ENSG00000105968	NA	NA	rs714543-G	rs714543	0	714543	intron_variant	FALSE	0.4346	2e-50	49.69897000433602	NA	0.0549308	[0.048-0.062] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4346	NA	0.0549308
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7q22.1	7	100408870	ZCWPW1	ZCWPW1	NA	NA	ENSG00000078487	NA	NA	rs68116612-A	rs68116612	0	68116612	intron_variant	FALSE	0.1948	5e-13	12.301029995663981	NA	0.03327809	[0.024-0.042] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1948	NA	0.03327809
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7q22.1	7	100629042	TFR2	TFR2	NA	NA	ENSG00000106327	NA	NA	rs4548095-T	rs4548095	0	4548095	intron_variant	FALSE	0.6356	2e-10	9.698970004336019	NA	0.0242055	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6356	NA	0.0242055
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7q22.1	7	101856650	CUX1	CUX1	NA	NA	ENSG00000257923	NA	NA	rs139141690-A	rs139141690	0	139141690	intron_variant	FALSE	0.005	4e-12	11.397940008672037	NA	0.1843694	[0.13-0.24] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.005	NA	0.1843694
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	7q31.2	7	116850412	CAPZA2	CAPZA2	NA	NA	ENSG00000198898	NA	NA	rs11321799-C	rs11321799	0	11321799	intron_variant	FALSE	0.3832	5e-11	10.301029995663981	NA	0.02487055	[0.017-0.032] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3832	NA	0.02487055
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q11	11	55587706	OR4C16, OR4C11	OR4C16 - OR4C11	ENSG00000279514	ENSG00000172188	NA	14646	14654	rs74237369-G	rs74237369	0	74237369	intergenic_variant	TRUE	NA	4e-6	5.3979400086720375	NA	0.162	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.5	11	1899025	NR	LINC01150	NA	NA	ENSG00000229671	NA	NA	rs7483477-T	rs7483477	0	7483477	intron_variant	FALSE	NA	1e-7	7	NA	0.144	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	16q23.3	16	83012185	CDH13	CDH13	NA	NA	ENSG00000140945	NA	NA	rs7500448-A	rs7500448	0	7500448	intron_variant	FALSE	NA	7e-7	6.154901959985743	NA	0.135	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q12.2	11	61510774	LRRC10B	LRRC10B	NA	NA	ENSG00000204950	NA	NA	rs751984-T	rs751984	0	751984	3_prime_UTR_variant	FALSE	NA	8e-16	15.096910013008056	NA	0.303	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3q22.2	3	134167861	RYK	RYK	NA	NA	ENSG00000163785	NA	NA	rs75305034-T	rs75305034	1	55688777	intron_variant	FALSE	NA	7e-14	13.154901959985743	NA	0.256	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p36.33	1	1808816	GNB1	GNB1	NA	NA	ENSG00000078369	NA	NA	rs7546498-G	rs7546498	0	7546498	intron_variant	FALSE	NA	5e-10	9.301029995663981	NA	0.147	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q36.3	2	226327727	LOC646736, MIR5702	NA	NA	NA	NA	NA	NA	rs7590201-G	rs7590201	0	7590201	TF_binding_site_variant	TRUE	NA	8e-9	8.096910013008056	NA	0.138	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q31.2	2	178889467	CCDC141	CCDC141	NA	NA	ENSG00000163492	NA	NA	rs7591091-T	rs7591091	0	7591091	intron_variant	FALSE	NA	2e-7	6.698970004336019	NA	0.131	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	2q11.2	2	96686103	FER1L5	FER1L5	NA	NA	ENSG00000249715	NA	NA	rs7599598-A	rs7599598	0	7599598	missense_variant	FALSE	NA	1e-7	7	NA	0.128	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p11.1	3	88688891	C3orf38, EPHA3	NDUFA5P5 - NA	ENSG00000242365	NA	NA	87489	NA	rs76217164-T	rs76217164	0	76217164	intergenic_variant	TRUE	NA	1e-7	7	NA	1.629	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	3p21.31	3	48694017	IP6K2	IP6K2	NA	NA	ENSG00000068745	NA	NA	rs76398786-C	rs76398786	0	76398786	3_prime_UTR_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.382	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	7q21.11	7	80758000	SEMA3C	SEMA3C	NA	NA	ENSG00000075223	NA	NA	rs76627715-T	rs76627715	0	76627715	intron_variant	FALSE	NA	1e-9	9	NA	0.216	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	4q25	4	108104223	LEF1	LEF1	NA	NA	ENSG00000138795	NA	NA	rs7665304-A	rs7665304	0	7665304	intron_variant	FALSE	NA	6e-8	7.221848749616356	NA	0.128	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q24.3	8	141386381	GPR20, PTP4A3	GPR20 - PTP4A3	ENSG00000204882	ENSG00000275575	NA	19095	5614	rs76735299-G	rs76735299	0	76735299	regulatory_region_variant	TRUE	NA	1e-7	7	NA	0.249	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q32	5	149010732	NR	SH3TC2	NA	NA	ENSG00000169247	NA	NA	rs7704297-T	rs7704297	0	7704297	intron_variant	FALSE	NA	5e-19	18.30102999566398	NA	0.263	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	5q31.1	5	132479312	C5orf56, IRF1	IRF1, IRF1-AS1	NA	NA	ENSG00000125347, ENSG00000197536	NA	NA	rs7734334-C	rs7734334	0	7734334	intron_variant	FALSE	NA	9e-10	9.045757490560675	NA	0.154	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	17p13.1	17	7668434	TP53	TP53	NA	NA	ENSG00000141510	NA	NA	rs78378222-T	rs78378222	0	78378222	3_prime_UTR_variant	FALSE	NA	1e-8	8	NA	0.638	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	1p22.2	1	88815846	PKN2	PKN2	NA	NA	ENSG00000065243	NA	NA	rs786919-A	rs786919	0	786919	intron_variant	FALSE	NA	4e-6	5.3979400086720375	NA	0.109	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11p15.3	11	13278705	ARNTL	ARNTL	NA	NA	ENSG00000133794	NA	NA	rs7928655-C	rs7928655	0	7928655	intron_variant	FALSE	NA	2e-8	7.698970004336019	NA	0.143	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	11q22.3	11	107211115	GUCY1A2, CWF19L2	ASS1P13 - NA	ENSG00000255353	NA	NA	33585	NA	rs7951348-C	rs7951348	0	7951348	intergenic_variant	TRUE	NA	2e-7	6.698970004336019	NA	0.12	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	12q24.31	12	123338164	SBNO1	SBNO1	NA	NA	ENSG00000139697	NA	NA	rs7980687-G	rs7980687	0	7980687	intron_variant	FALSE	NA	2e-11	10.698970004336019	NA	0.196	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	13q34	13	110307296	COL4A2	COL4A2	NA	NA	ENSG00000134871	NA	NA	rs7989823-A	rs7989823	0	7989823	5_prime_UTR_variant	FALSE	NA	6e-9	8.221848749616356	NA	0.15	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	8q24.12	8	119454719	NR	CCN3 - NA	ENSG00000136999	NA	NA	30285	NA	rs80309268-T	rs80309268	0	80309268	intron_variant	TRUE	NA	1e-16	16	NA	0.242	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	19q12	19	31436641	TSHZ3, THEG5	TSHZ3-AS1 - LINC02841	ENSG00000267662	ENSG00000267407	NA	18847	83514	rs8105753-A	rs8105753	0	8105753	regulatory_region_variant	TRUE	NA	2e-8	7.698970004336019	NA	0.137	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals	NA	22q11.21	22	17985603	MICAL3	MICAL3	NA	NA	ENSG00000243156	NA	NA	rs8139817-A	rs8139817	0	8139817	intron_variant	FALSE	NA	4e-8	7.3979400086720375	NA	0.143	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007094	Genome-wide genotyping array	NA	NA	NA
2017-06-06	28273873	Park YM	2017-03-05	Nutrients	www.ncbi.nlm.nih.gov/pubmed/28273873	Interaction between Single Nucleotide Polymorphism and Urinary Sodium, Potassium, and Sodium-Potassium Ratio on the Risk of Hypertension in Korean Adults.	Hypertension	8,839 Korean ancestry individuals.	NA	1q41	1	221099816	LOC101929750	NA	NA	NA	NA	NA	NA	rs7554672-?	rs7554672	0	7554672	intergenic_variant	TRUE	0.589	2e-6	5.698970004336019	NA	1.21	NA	Affymetrix [1291657] (imputed)	N	hypertension	http://www.ebi.ac.uk/efo/EFO_0000537	GCST004143	Genome-wide genotyping array	0.589	1.21	NA
2017-06-06	28273873	Park YM	2017-03-05	Nutrients	www.ncbi.nlm.nih.gov/pubmed/28273873	Interaction between Single Nucleotide Polymorphism and Urinary Sodium, Potassium, and Sodium-Potassium Ratio on the Risk of Hypertension in Korean Adults.	Hypertension	8,839 Korean ancestry individuals.	NA	7q32.3	7	131507716	MKLN1, PODXL	PODXL	NA	NA	ENSG00000128567	NA	NA	rs3800688-G	rs3800688	0	3800688	intron_variant	FALSE	0.479	4e-6	5.3979400086720375	NA	1.197	NA	Affymetrix [1291657] (imputed)	N	hypertension	http://www.ebi.ac.uk/efo/EFO_0000537	GCST004143	Genome-wide genotyping array	0.479	1.197	NA
2017-06-06	28273873	Park YM	2017-03-05	Nutrients	www.ncbi.nlm.nih.gov/pubmed/28273873	Interaction between Single Nucleotide Polymorphism and Urinary Sodium, Potassium, and Sodium-Potassium Ratio on the Risk of Hypertension in Korean Adults.	Hypertension	8,839 Korean ancestry individuals.	NA	12q21.33	12	89680664	ATP2B1	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs11105368-?	rs11105368	0	11105368	intron_variant	FALSE	0.624	2e-7	6.698970004336019	NA	1.23	NA	Affymetrix [1291657] (imputed)	N	hypertension	http://www.ebi.ac.uk/efo/EFO_0000537	GCST004143	Genome-wide genotyping array	0.624	1.23	NA
2017-07-04	28317342	Hivert MF	2017-03-20	Obesity (Silver Spring)	www.ncbi.nlm.nih.gov/pubmed/28317342	Genetic determinants of adiponectin regulation revealed by pregnancy.	Adiponectin levels in pregnancy	1,322 European ancestry individuals	522 European ancestry individuals, 174 French Canadian founder individuals	3q27.3	3	186841671	ADIPOQ	LINC02043 - ADIPOQ	ENSG00000232233	ENSG00000181092	NA	16150	1033	rs17300539-G	rs17300539	0	17300539	regulatory_region_variant	TRUE	0.92	9e-6	5.045757490560675	(adjusted for BMI, height & mean arterial pressure)	0.26	[0.15-0.37] unit decrease	Illumina [NR]	N	adiponectin measurement	http://www.ebi.ac.uk/efo/EFO_0004502	GCST004289	Genome-wide genotyping array	0.92	NA	0.26
2017-07-04	28317342	Hivert MF	2017-03-20	Obesity (Silver Spring)	www.ncbi.nlm.nih.gov/pubmed/28317342	Genetic determinants of adiponectin regulation revealed by pregnancy.	Adiponectin levels in pregnancy	1,322 European ancestry individuals	522 European ancestry individuals, 174 French Canadian founder individuals	13q13.3	13	37292760	CSNK1A1L	RPS12P24 - NA	ENSG00000230283	NA	NA	71514	NA	rs1408236-A	rs1408236	0	1408236	intergenic_variant	TRUE	0.98	5e-6	5.301029995663981	(adjusted for BMI, height & mean arterial pressure)	0.644	[0.37-0.92] unit decrease	Illumina [NR]	N	adiponectin measurement	http://www.ebi.ac.uk/efo/EFO_0004502	GCST004289	Genome-wide genotyping array	0.98	NA	0.644
2017-07-04	28317342	Hivert MF	2017-03-20	Obesity (Silver Spring)	www.ncbi.nlm.nih.gov/pubmed/28317342	Genetic determinants of adiponectin regulation revealed by pregnancy.	Adiponectin levels in pregnancy	1,322 European ancestry individuals	522 European ancestry individuals, 174 French Canadian founder individuals	3q25.31	3	157080986	CCNL1, LEKR1	LEKR1 - LINC00880	ENSG00000197980	ENSG00000243629	NA	34857	681	rs900400-T	rs900400	0	900400	intergenic_variant	TRUE	0.61	1e-7	7	NA	0.179	[0.11-0.25] unit decrease	Illumina [NR]	N	adiponectin measurement	http://www.ebi.ac.uk/efo/EFO_0004502	GCST004289	Genome-wide genotyping array	0.61	NA	0.179
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	17q21.1	17	39869916	ZPBP2	ZPBP2	NA	NA	ENSG00000186075	NA	NA	rs11655198-?	rs11655198	0	11655198	intron_variant	FALSE	NR	1e-63	63	NA	1.1806375	[1.16-1.2]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.1806375	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	6p21.32	6	32635710	HLA-DRB5, HLA-DQA1	HLA-DQA1, HLA-DQA1	NA	NA	ENSG00000206305, ENSG00000196735	NA	NA	rs3104367-?	rs3104367	0	3104367	intron_variant	FALSE	NR	1e-40	40	NA	1.1467891	[1.12-1.17]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.1467891	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	9p24.1	9	6208030	RANBP6, IL33	GTF3AP1 - IL33	ENSG00000237274	ENSG00000137033	NA	10782	7756	rs144829310-?	rs144829310	0	144829310	intergenic_variant	TRUE	NR	1e-31	31	NA	1.165	[1.136-1.195]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.165	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	5q22.1	5	111066174	SLC25A46, TSLP	BCLAF1P1 - TSLP	ENSG00000248966	ENSG00000145777	NA	115394	3888	rs1837253-?	rs1837253	0	1837253	intergenic_variant	TRUE	NR	3e-31	30.522878745280337	NA	1.1415524	[1.12-1.17]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.1415524	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	2q12.1	2	102297183	IL1RL2, IL1RL1	FAM183DP - IL1RL1	ENSG00000205716	ENSG00000115602	NA	46928	14319	rs202011557-?	rs202011557	0	202011557	intergenic_variant	TRUE	NR	5e-31	30.30102999566398	NA	1.1876484	[1.15-1.22]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.1876484	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	15q22.33	15	67156025	SMAD3	SMAD3	NA	NA	ENSG00000166949	NA	NA	rs56375023-?	rs56375023	0	56375023	intron_variant	FALSE	NR	2e-21	20.69897000433602	NA	1.1148272	[1.09-1.14]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.1148272	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	11q13.5	11	76582714	C11orf30, LRRC32	EMSY - LINC02757	ENSG00000158636	ENSG00000255363	NA	29689	25139	rs7936323-?	rs7936323	0	7936323	intergenic_variant	TRUE	NR	1e-16	16	NA	1.0845987	[1.06-1.1]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.0845987	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	6p21.33	6	31354420	HLA-C, MICA	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B, HLA-B	NA	NA	ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000232126, ENSG00000224608, ENSG00000206450	NA	NA	rs2428494-?	rs2428494	0	2428494	intron_variant	FALSE	NR	1e-16	16	NA	1.0869565	[1.06-1.11]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.0869565	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	5q31.1	5	132565533	RAD50	RAD50	NA	NA	ENSG00000113522	NA	NA	rs2244012-?	rs2244012	0	2244012	intron_variant	FALSE	NR	2e-16	15.698970004336019	NA	1.102	[1.077-1.128]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.102	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	2q37.3	2	241759225	D2HGDH	D2HGDH	NA	NA	ENSG00000180902	NA	NA	rs34290285-?	rs34290285	0	34290285	intron_variant	FALSE	NR	2e-15	14.698970004336019	NA	1.107	[1.079-1.135]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.107	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	16p13.13	16	11136846	CLEC16A	CLEC16A	NA	NA	ENSG00000038532	NA	NA	rs7203459-?	rs7203459	0	7203459	intron_variant	FALSE	NR	4e-15	14.397940008672037	NA	1.092	[1.068-1.117]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.092	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	1q23.3	1	161189357	B4GALT3, ADAMTS4	ADAMTS4	NA	NA	ENSG00000158859	NA	NA	rs4233366-?	rs4233366	0	4233366	3_prime_UTR_variant	FALSE	NR	5e-15	14.301029995663981	NA	1.09	[1.067-1.114]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.09	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	10p14	10	9007290	GATA3	LINC02676 - LINC00709	ENSG00000234752	ENSG00000230014	NA	92694	268543	rs12413578-?	rs12413578	0	12413578	regulatory_region_variant	TRUE	NR	8e-12	11.096910013008056	NA	1.1223345	[1.09-1.16]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.1223345	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	8q21.13	8	80372904	TPD52, ZBTB10	MIR5708 - RNU6-1213P	ENSG00000265588	ENSG00000252884	NA	131431	32612	rs10957978-?	rs10957978	0	10957978	intron_variant	TRUE	NR	1e-11	11	NA	1.0706638	[1.05-1.09]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.0706638	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	15q22.2	15	60776505	RORA	RORA	NA	NA	ENSG00000069667	NA	NA	rs10519068-?	rs10519068	0	10519068	intron_variant	FALSE	NR	4e-11	10.397940008672037	NA	1.1	[1.069-1.132]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.1	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	4p14	4	38797027	TLR1	TLR1	NA	NA	ENSG00000174125	NA	NA	rs5743618-?	rs5743618	0	5743618	missense_variant	FALSE	NR	4e-11	10.397940008672037	NA	1.082	[1.057-1.107]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.082	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	6q15	6	90275479	BACH2	BACH2	NA	NA	ENSG00000112182	NA	NA	rs58521088-?	rs58521088	0	58521088	intron_variant	FALSE	NR	7e-11	10.154901959985743	NA	1.0706638	[1.05-1.09]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.0706638	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	12q13.3	12	57115272	STAT6, LRP1	STAT6	NA	NA	ENSG00000166888	NA	NA	rs3001426-?	rs3001426	0	3001426	intron_variant	FALSE	NR	1e-10	10	NA	1.066098	[1.05-1.09]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.066098	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	3q28	3	188684683	LPP	LPP	NA	NA	ENSG00000145012	NA	NA	rs73196739-?	rs73196739	0	73196739	intron_variant	FALSE	NR	7e-9	8.154901959985743	NA	1.0845987	[1.05-1.11]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.0845987	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	1q32.1	1	203131376	ADORA1	ADORA1	NA	NA	ENSG00000163485	NA	NA	rs6683383-?	rs6683383	0	6683383	intron_variant	FALSE	NR	1e-8	8	NA	1.062	[1.040-1.084]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.062	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	2p25.1	2	8317950	ID2	LINC00299	NA	NA	ENSG00000236790	NA	NA	rs13412757-?	rs13412757	0	13412757	intron_variant	FALSE	NR	1e-8	8	NA	1.062	[1.040-1.084]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.062	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	1q24.2	1	167464183	CD247	CD247	NA	NA	ENSG00000198821	NA	NA	rs1723018-?	rs1723018	0	1723018	intron_variant	FALSE	NR	1e-8	8	NA	1.0582011	[1.04-1.08]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.0582011	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	14q24.1	14	68283210	RAD51B	RAD51B	NA	NA	ENSG00000182185	NA	NA	rs3784099-?	rs3784099	0	3784099	intron_variant	FALSE	NR	2e-8	7.698970004336019	NA	1.0615711	[1.04-1.08]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.0615711	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	7q22.3	7	106036059	CDHR3	CDHR3	NA	NA	ENSG00000128536	NA	NA	rs6959584-?	rs6959584	0	6959584	3_prime_UTR_variant	FALSE	NR	2e-8	7.698970004336019	NA	1.086	[1.055-1.117]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.086	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	5q31.3	5	142150197	NDFIP1	NDFIP1	NA	NA	ENSG00000131507	NA	NA	rs200634877-?	rs200634877	0	200634877	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	1.0638298	[1.04-1.09]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.0638298	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	6q16.1	6	96612248	FHL5	FHL5	NA	NA	ENSG00000112214	NA	NA	rs9486719-?	rs9486719	0	9486719	intron_variant	FALSE	NR	6e-21	20.221848749616356	NA	1.091703	[1.07-1.11]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.091703	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	6p24.1	6	12903725	PHACTR1	PHACTR1	NA	NA	ENSG00000112137	NA	NA	rs9349379-?	rs9349379	0	9349379	intron_variant	FALSE	NR	2e-20	19.69897000433602	NA	1.0741138	[1.06-1.09]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.0741138	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	2q37.1	2	233916086	MSL3P1, TRPM8	MSL3P1 - TRPM8	ENSG00000224287	ENSG00000144481	NA	47642	1287	rs1965629-?	rs1965629	0	1965629	intergenic_variant	TRUE	NR	7e-19	18.154901959985743	NA	1.0893246	[1.07-1.11]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.0893246	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	12p13.32	12	4419506	FGF23, FGF6	FGF23 - FGF6	ENSG00000118972	ENSG00000111241	NA	39794	8649	rs140668749-?	rs140668749	0	140668749	intergenic_variant	TRUE	NR	1e-18	18	NA	1.07	[1.054-1.086]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.07	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	1q22	1	156481081	MEF2D	MEF2D	NA	NA	ENSG00000116604	NA	NA	rs2274319-?	rs2274319	0	2274319	intron_variant	FALSE	NR	2e-18	17.69897000433602	NA	1.072	[1.056-1.089]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.072	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	20p11.23	20	19485263	SLC24A3	SLC24A3	NA	NA	ENSG00000185052	NA	NA	rs6081613-?	rs6081613	0	6081613	intron_variant	FALSE	NR	2e-15	14.698970004336019	NA	1.0695187	[1.05-1.09]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.0695187	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	1p13.2	1	115135325	TSPAN2, NGF	LINC01765 - NA	ENSG00000233730	NA	NA	32667	NA	rs12134493-?	rs12134493	0	12134493	TF_binding_site_variant	TRUE	NR	2e-13	12.698970004336019	NA	1.0893246	[1.06-1.11]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.0893246	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	1p31.1	1	73402703	LRRIQ3	LINC01360 - NA	ENSG00000233973	NA	NA	47450	NA	rs1923243-?	rs1923243	0	1923243	intergenic_variant	TRUE	NR	2e-10	9.698970004336019	NA	1.049	[1.034-1.065]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.049	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	2q33.2	2	202912503	ALS2CR8	WDR12, CARF	NA	NA	ENSG00000138442, ENSG00000138380	NA	NA	rs149163995-?	rs149163995	0	149163995	5_prime_UTR_variant	FALSE	NR	4e-10	9.397940008672037	NA	1.0822511	[1.05-1.11]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.0822511	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	17q25.3	17	80286212	RNF213	RNF213	NA	NA	ENSG00000173821	NA	NA	rs7220465-?	rs7220465	0	7220465	intron_variant	FALSE	NR	5e-10	9.301029995663981	NA	1.0582011	[1.04-1.08]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.0582011	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	10q23.33	10	94278929	PLCE1	PLCE1, PLCE1-AS1	NA	NA	ENSG00000138193, ENSG00000268894	NA	NA	rs11187838-?	rs11187838	0	11187838	non_coding_transcript_exon_variant	FALSE	NR	1e-9	9	NA	1.047	[1.032-1.063]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.047	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	16q24.2	16	87544433	ZCCHC14, JPH3	ZCCHC14 - JPH3	ENSG00000140948	ENSG00000154118	NA	51409	57402	rs8052831-?	rs8052831	0	8052831	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	NA	1.049	[1.033-1.066]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.049	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	11p15.4	11	10652497	MRVI1, CTR9	IRAG1	NA	NA	ENSG00000072952	NA	NA	rs4910165-?	rs4910165	0	4910165	intron_variant	FALSE	NR	2e-9	8.698970004336019	NA	1.05	[1.033-1.067]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.05	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	14q12	14	27191653	NOVA1	NA	NA	NA	NA	NA	NA	rs1245465-?	rs1245465	0	1245465	intron_variant	TRUE	NR	3e-9	8.522878745280337	NA	1.046	[1.031-1.062]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.046	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	14q32.12	14	93129246	ITPK1, MOAP1	ITPK1 - CYB5AP3	ENSG00000274958	ENSG00000281141	NA	12926	8820	rs11624776-?	rs11624776	0	11624776	regulatory_region_variant	TRUE	NR	4e-9	8.397940008672037	NA	1.049318	[1.03-1.07]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.049318	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	7p14.1	7	40378133	C7orf10	SUGCT	NA	NA	ENSG00000175600	NA	NA	rs61693171-?	rs61693171	0	61693171	intron_variant	FALSE	NR	9e-9	8.045757490560675	NA	1.073	[1.047-1.098]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.073	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	10q26.3	10	132754883	INPP5A	INPP5A	NA	NA	ENSG00000068383	NA	NA	rs3793683-?	rs3793683	0	3793683	intron_variant	FALSE	NR	2e-8	7.698970004336019	NA	1.046	[1.030-1.063]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.046	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	9p21.1	9	29372503	LINGO2	IFNA14 - NA	ENSG00000228083	NA	NA	8132498	NA	rs10156578-?	rs10156578	0	10156578	intergenic_variant	TRUE	NR	2e-8	7.698970004336019	NA	1.0449321	[1.03-1.06]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.0449321	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	9q33.1	9	116482904	ASTN2	ASTN2	NA	NA	ENSG00000148219	NA	NA	rs7030607-?	rs7030607	0	7030607	intron_variant	FALSE	NR	2e-8	7.698970004336019	NA	1.046	[1.029-1.062]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.046	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	7q11.23	7	73443388	BAZ1B	BAZ1B	NA	NA	ENSG00000009954	NA	NA	rs202203062-?	rs202203062	0	202203062	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	1.061	[1.039-1.083]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.061	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	20q13.12	20	47212407	ZMYND8	ZMYND8	NA	NA	ENSG00000101040	NA	NA	rs910187-?	rs910187	0	910187	intron_variant	FALSE	NR	4e-8	7.3979400086720375	NA	1.045	[1.029-1.061]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.045	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	16q23.1	16	75408247	CFDP1	CFDP1	NA	NA	ENSG00000153774	NA	NA	rs200914569-?	rs200914569	0	200914569	intron_variant	FALSE	NR	6e-8	7.221848749616356	NA	1.0449321	[1.03-1.06]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.0449321	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	18q21.31	18	57511578	ONECUT2, FECH	ONECUT2 - FECH	ENSG00000119547	ENSG00000066926	NA	20280	32799	rs10871745-?	rs10871745	0	10871745	intergenic_variant	TRUE	NR	6e-8	7.221848749616356	NA	1.045	[1.029-1.062]	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	1.045	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	6p21.2	6	39215694	intergenic	KCNK5	NA	NA	ENSG00000164626	NA	NA	rs10456100-?	rs10456100	0	10456100	intron_variant	FALSE	NR	5e-7	6.301029995663981	NA	NA	NA	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Migraine	53,109 European ancestry cases, 230,876 European ancestry controls	NA	6q22.31	6	121495733	intergenic	RNU4-35P - RNU4-76P	ENSG00000199458	ENSG00000201379	NA	41612	46753	rs9490306-?	rs9490306	0	9490306	intergenic_variant	TRUE	NR	6e-6	5.221848749616356	NA	NA	NA	Illumina [13763073] (imputed)	N	migraine disorder	http://www.ebi.ac.uk/efo/EFO_0003821	GCST003986	Genome-wide genotyping array	NA	NA	NA
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9q22.33	9	97938372	HEMGN	HEMGN	NA	NA	ENSG00000136929	NA	NA	rs3758253-T	rs3758253	0	3758253	intron_variant	FALSE	0.3633	1e-22	22	NA	0.03717625	[0.03-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3633	NA	0.03717625
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9q33.3	9	124427636	intergenic	PSMB7 - ADGRD2	ENSG00000136930	ENSG00000180264	NA	12192	23789	rs10818963-A	rs10818963	0	10818963	intergenic_variant	TRUE	0.6524	7e-10	9.154901959985743	NA	0.02427277	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6524	NA	0.02427277
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9q34.11	9	128704210	PKN3	PKN3	NA	NA	ENSG00000160447	NA	NA	rs13289095-T	rs13289095	0	13289095	intron_variant	FALSE	0.1453	6e-11	10.221848749616356	NA	0.03391913	[0.024-0.044] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1453	NA	0.03391913
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9q34.13	9	132989126	GFI1B	GFI1B	NA	NA	ENSG00000165702	NA	NA	rs150813342-T	rs150813342	0	150813342	synonymous_variant	FALSE	0.0079	6e-27	26.221848749616356	NA	0.2309338	[0.19-0.27] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0079	NA	0.2309338
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	9q34.2	9	133254260	RP11-430N14.4, ABO	ABO, ABO	NA	NA	ENSG00000175164, ENSG00000281879	NA	NA	rs8176759-A	rs8176759	0	8176759	non_coding_transcript_exon_variant	FALSE	0.0645	2e-10	9.698970004336019	NA	0.04763889	[0.033-0.062] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0645	NA	0.04763889
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	10p12.1	10	24911877	PRTFDC1	PRTFDC1	NA	NA	ENSG00000099256	NA	NA	rs140884840-A	rs140884840	0	140884840	intron_variant	FALSE	0.3713	7e-13	12.154901959985743	NA	0.02712682	[0.02-0.035] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3713	NA	0.02712682
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	10p12.1	10	27188019	MASTL	ACBD5	NA	NA	ENSG00000107897	NA	NA	rs788210-C	rs788210	0	788210	intron_variant	FALSE	0.1826	1e-10	10	NA	0.03035086	[0.021-0.04] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1826	NA	0.03035086
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	10q11.23	10	49055156	VSTM4	VSTM4	NA	NA	ENSG00000165633	NA	NA	rs4272720-G	rs4272720	0	4272720	intron_variant	FALSE	0.2362	3e-19	18.522878745280337	NA	0.0387588	[0.03-0.047] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2362	NA	0.0387588
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	10q21.2	10	62058666	ARID5B	ARID5B	NA	NA	ENSG00000150347	NA	NA	rs10821952-A	rs10821952	0	10821952	intron_variant	FALSE	0.5667	1e-9	9	NA	0.02286182	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.5667	NA	0.02286182
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	10q22.3	10	79404390	RP11-342M3.5, ZCCHC24	ZCCHC24	NA	NA	ENSG00000165424	NA	NA	rs116052829-T	rs116052829	0	116052829	intron_variant	FALSE	0.1049	1e-10	10	NA	0.03848108	[0.027-0.05] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.1049	NA	0.03848108
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	10q23.33	10	93079885	CYP26A1	CYP26A1 - NIP7P1	ENSG00000095596	ENSG00000232805	NA	2000	26987	rs2068888-A	rs2068888	0	2068888	regulatory_region_variant	TRUE	0.4509	9e-11	10.045757490560675	NA	0.0238492	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4509	NA	0.0238492
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	10q23.33	10	94266428	PLCE1	PLCE1	NA	NA	ENSG00000138193	NA	NA	rs11289753-C	rs11289753	0	11289753	intron_variant	FALSE	0.4342	9e-12	11.045757490560675	NA	0.02519623	[0.018-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4342	NA	0.02519623
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	10q24.2	10	99518968	intergenic	GOT1 - LINC01475	ENSG00000120053	ENSG00000257582	NA	88344	7382	rs11190133-T	rs11190133	0	11190133	intergenic_variant	TRUE	0.2842	4e-10	9.397940008672037	NA	0.02528815	[0.017-0.033] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2842	NA	0.02528815
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11p15.5	11	200343	BET1L	BET1L	NA	NA	ENSG00000177951	NA	NA	rs55966801-C	rs55966801	0	55966801	intron_variant	FALSE	0.2309	3e-24	23.522878745280337	NA	0.04483173	[0.036-0.053] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.2309	NA	0.04483173
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11p15.5	11	2687789	KCNQ1OT1	KCNQ1OT1, KCNQ1	NA	NA	ENSG00000269821, ENSG00000053918	NA	NA	rs231353-G	rs231353	0	231353	non_coding_transcript_exon_variant	FALSE	0.3493	2e-9	8.698970004336019	NA	0.02308014	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3493	NA	0.02308014
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11p15.4	11	2870735	KCNQ1DN	KCNQ1DN, KCNQ1DN	NA	NA	ENSG00000278855, ENSG00000237941	NA	NA	rs2239897-G	rs2239897	0	2239897	non_coding_transcript_exon_variant	FALSE	0.0637	4e-9	8.397940008672037	NA	0.04672705	[0.031-0.062] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0637	NA	0.04672705
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11p15.4	11	8797456	ST5, RP11-318C2.1	DENND2B	NA	NA	ENSG00000166444	NA	NA	rs10769960-C	rs10769960	0	10769960	intron_variant	FALSE	0.4367	1e-15	15	NA	0.02992373	[0.023-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4367	NA	0.02992373
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11p11.2	11	47789945	NUP160	NUP160	NA	NA	ENSG00000030066	NA	NA	rs34563280-C	rs34563280	0	34563280	intron_variant	FALSE	0.4355	2e-12	11.698970004336019	NA	0.02640469	[0.019-0.034] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4355	NA	0.02640469
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11q12.2	11	61852357	FADS2	FADS2	NA	NA	ENSG00000134824	NA	NA	rs174594-A	rs174594	0	174594	intron_variant	FALSE	0.6242	9e-10	9.045757490560675	NA	0.02313224	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.6242	NA	0.02313224
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11q13.1	11	65486329	intergenic	NEAT1 - LINC02736	ENSG00000245532	ENSG00000279243	NA	40789	912	rs587080-C	rs587080	0	587080	regulatory_region_variant	TRUE	0.3356	2e-10	9.698970004336019	NA	0.02472482	[0.017-0.032] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3356	NA	0.02472482
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11q13.4	11	73236889	RP11-800A3.4	P2RY2	NA	NA	ENSG00000175591	NA	NA	rs11235688-A	rs11235688	0	11235688	3_prime_UTR_variant	FALSE	0.4175	6e-10	9.221848749616356	NA	0.0230823	[0.016-0.03] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4175	NA	0.0230823
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11q22.1	11	100630840	intergenic	NA - RN7SL222P	NA	ENSG00000242165	NA	NA	11135	rs1111890-G	rs1111890	0	1111890	regulatory_region_variant	TRUE	0.3655	2e-13	12.698970004336019	NA	0.02790585	[0.02-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.3655	NA	0.02790585
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11q22.3	11	108174268	NPAT	NPAT	NA	NA	ENSG00000149308	NA	NA	rs7129527-G	rs7129527	0	7129527	intron_variant	FALSE	0.4088	1e-26	26	NA	0.04004646	[0.033-0.047] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.4088	NA	0.04004646
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11q23.2	11	114082900	ZBTB16	ZBTB16	NA	NA	ENSG00000109906	NA	NA	rs73000929-A	rs73000929	0	73000929	intron_variant	FALSE	0.0373	1e-9	9	NA	0.0597131	[0.04-0.079] unit decrease	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.0373	NA	0.0597131
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Plateletcrit	164,339 European ancestry individuals	NA	11q23.3	11	116831646	APOC3	APOC3	NA	NA	ENSG00000110245	NA	NA	rs645901-C	rs645901	0	645901	intron_variant	FALSE	0.8657	2e-10	9.698970004336019	NA	0.03454995	[0.024-0.045] unit increase	Affymetrix [~ 2500000] (imputed)	N	platelet crit	http://www.ebi.ac.uk/efo/EFO_0007985	GCST004607	Genome-wide genotyping array	0.8657	NA	0.03454995
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	1p36.13	1	19512621	CAPZB, MINOS1	MICOS10	NA	NA	ENSG00000173436	NA	NA	rs12138950-?	rs12138950	0	12138950	intron_variant	FALSE	NR	8e-9	8.096910013008056	NA	1.1074197	[1.07-1.15]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.1074197	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	13q12.12	13	24200509	SPATA13	SPATA13	NA	NA	ENSG00000182957	NA	NA	rs9511143-?	rs9511143	0	9511143	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	1.0869565	[1.05-1.12]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.0869565	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	10q21.2	10	62292578	RTKN2, ZNF365	LINC02621	NA	NA	ENSG00000234756	NA	NA	rs10821973-?	rs10821973	0	10821973	intron_variant	FALSE	NR	4e-8	7.3979400086720375	NA	1.07	[1.04-1.10]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.07	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	12q13.2	12	56073803	RPS26, ERBB3	RPS26 - ERBB3	ENSG00000197728	ENSG00000065361	NA	29106	2996	rs7312770-?	rs7312770	0	7312770	intergenic_variant	TRUE	NR	8e-8	7.096910013008056	NA	1.0729614	[1.05-1.10]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.0729614	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	16q23.3	16	83624538	CDH13	CDH13	NA	NA	ENSG00000140945	NA	NA	rs7193703-?	rs7193703	0	7193703	intron_variant	FALSE	NR	8e-8	7.096910013008056	NA	20.408165	[3.97-100.00]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	20.408165	NA
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	1q32.1	1	205667206	SLC45A3	SLC45A3	NA	NA	ENSG00000158715	NA	NA	rs4951018-C	rs4951018	0	4951018	intron_variant	FALSE	0.22	1e-8	8	NA	0.0394282	[0.027-0.052] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.22	NA	0.0394282
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	2p16.1	2	60532612	BCL11A	BCL11A	NA	NA	ENSG00000119866	NA	NA	rs2556375-G	rs2556375	0	2556375	intron_variant	FALSE	0.17	6e-19	18.221848749616356	NA	0.0652336	[0.051-0.08] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.17	NA	0.0652336
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	4q32.1	4	156613097	PDGFC	NA - LINC02272	NA	ENSG00000251283	NA	NA	21397	rs10023685-G	rs10023685	0	10023685	intergenic_variant	TRUE	0.37	2e-9	8.698970004336019	NA	0.0346789	[0.023-0.046] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.37	NA	0.0346789
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	5p15.33	5	1356569	TERT, CLPTM1L	LINC01511	NA	NA	ENSG00000250584	NA	NA	rs37004-C	rs37004	0	37004	intron_variant	FALSE	0.79	9e-13	12.045757490560675	NA	0.0604747	[0.044-0.077] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.79	NA	0.0604747
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	6p21.1	6	43742611	VEGFA	MRPS18A - VEGFA	ENSG00000096080	ENSG00000112715	NA	54820	27573	rs6920449-T	rs6920449	0	6920449	regulatory_region_variant	TRUE	0.16	6e-12	11.221848749616356	NA	0.0529541	[0.038-0.068] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.16	NA	0.0529541
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	8p21.2	8	23670998	NKX3-1	SINHCAFP3 - NKX3-1	ENSG00000253488	ENSG00000167034	NA	35491	7699	rs13272392-T	rs13272392	0	13272392	intergenic_variant	TRUE	0.43	4e-34	33.39794000867204	NA	0.0685113	[0.057-0.08] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.43	NA	0.0685113
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	8q24.21	8	127395198	MYC	CASC8, POU5F1B, PCAT1	NA	NA	ENSG00000246228, ENSG00000212993, ENSG00000253438	NA	NA	rs10505477-A	rs10505477	0	10505477	intron_variant	FALSE	0.49	7e-21	20.154901959985743	NA	0.0525797	[0.042-0.064] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.49	NA	0.0525797
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	9q33.1	9	117970471	TLR4	NA	NA	NA	NA	NA	NA	rs6478343-C	rs6478343	0	6478343	intron_variant	TRUE	0.82	2e-8	7.698970004336019	NA	0.0415085	[0.027-0.056] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.82	NA	0.0415085
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	10p12.31	10	22292652	COMMD3, BMI1, SPAG6	RPL31P45 - COMMD3	ENSG00000233318	ENSG00000148444	NA	25306	23734	rs116940348-A	rs116940348	0	116940348	intergenic_variant	TRUE	0.03	1e-14	14	NA	0.144017	[0.11-0.18] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.03	NA	0.144017
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	10q11.22	10	46046326	MSMB	MSMB	NA	NA	ENSG00000263639	NA	NA	rs10993994-T	rs10993994	0	10993994	5_prime_UTR_variant	FALSE	0.39	1e-50	50	NA	0.0843414	[0.073-0.095] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.39	NA	0.0843414
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	11p13	11	34761870	EHF, APIP	EHF - APIP	ENSG00000135373	ENSG00000149089	NA	98582	91224	rs4378355-C	rs4378355	0	4378355	intergenic_variant	TRUE	0.39	2e-10	9.698970004336019	NA	0.0368406	[0.025-0.048] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.39	NA	0.0368406
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	11q22.2	11	102525876	MMP7	MMP7	NA	NA	ENSG00000137673	NA	NA	rs12285347-C	rs12285347	0	12285347	intron_variant	FALSE	0.46	8e-12	11.096910013008056	NA	0.038463	[0.027-0.049] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.46	NA	0.038463
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	12q24.21	12	114656455	TBX3	OSTF1P1 - Y_RNA	ENSG00000258244	ENSG00000199964	NA	67653	1494	rs11067228-A	rs11067228	0	11067228	TF_binding_site_variant	TRUE	0.54	1e-14	14	NA	0.0439143	[0.033-0.055] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.54	NA	0.0439143
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	14q32.13	14	94631219	SERPINA3	SERPINA3 - ADIPOR1P2	ENSG00000196136	ENSG00000258805	NA	7164	644	rs8023057-A	rs8023057	0	8023057	intergenic_variant	TRUE	0.82	2e-15	14.698970004336019	NA	0.06069	[0.046-0.076] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.82	NA	0.06069
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	16p13.3	16	4299110	GLIS2, TFAP4	TFAP4 - GLIS2	ENSG00000090447	ENSG00000126603	NA	26035	15651	rs9921192-C	rs9921192	0	9921192	TF_binding_site_variant	TRUE	0.5	1e-9	9	NA	0.0350975	[0.024-0.046] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.5	NA	0.0350975
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	10q26.13	10	121425789	WDR11, FGFR2	RN7SKP167 - FGFR2	ENSG00000222979	ENSG00000066468	NA	14589	52543	rs10749415-?	rs10749415	0	10749415	intergenic_variant	TRUE	0.95	9e-25	24.045757490560675	(conditional on Round 3 SNPs)	0.117	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.95	NA	0.117
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	NA	NA	NA	KLK3	NA	NA	NA	NA	NA	NA	rs11665748-?	rs11665748	0	11665748	intergenic_variant	TRUE	0.65	3e-54	53.52287874528034	(conditional on Round 1 SNPs)	0.09	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.65	NA	0.09
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	13q14.3	13	50871978	intergenic	DLEU1, RNASEH2B-AS1	NA	NA	ENSG00000176124, ENSG00000233672	NA	NA	rs12429206-?	rs12429206	0	12429206	intron_variant	FALSE	0.343	7e-8	7.154901959985743	(conditional on Round 3 SNPs)	0.031	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.343	NA	0.031
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	11q24.3	11	129444288	intergenic	BARX2	NA	NA	ENSG00000043039	NA	NA	rs147520802-?	rs147520802	0	147520802	intron_variant	FALSE	0.017	3e-6	5.522878745280337	(conditional on Round 4 SNPs)	0.109	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.017	NA	0.109
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	8q24.21	8	127330621	MYC	POU5F1B, CASC8, PCAT1	NA	NA	ENSG00000212993, ENSG00000246228, ENSG00000253438	NA	NA	rs17464492-?	rs17464492	0	17464492	intron_variant	FALSE	0.71	2e-10	9.698970004336019	(conditional on Round 1 SNPs)	0.04	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.71	NA	0.04
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	3q23	3	141414608	ZBTB38	ZBTB38	NA	NA	ENSG00000177311	NA	NA	rs1991431-?	rs1991431	0	1991431	intron_variant	FALSE	0.43	3e-11	10.522878745280337	(conditional on Round 1 SNPs)	0.037	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.43	NA	0.037
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	NA	NA	NA	WDR11, FGFR2	NA	NA	NA	NA	NA	NA	rs200367988-?	rs200367988	0	200367988	intergenic_variant	TRUE	0.33	5e-18	17.30102999566398	(conditional on Round 1 SNPs)	0.051	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.33	NA	0.051
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	10p12.1	10	27805490	ARMC4	ODAD2	NA	NA	ENSG00000169126	NA	NA	rs2492906-?	rs2492906	0	2492906	intron_variant	FALSE	0.79	1e-8	8	(conditional on Round 1 SNPs)	0.037	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.79	NA	0.037
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	NA	NA	NA	KLK3	NA	NA	NA	NA	NA	NA	rs266849-A	rs266849	0	266849	intron_variant	TRUE	0.79	4e-17	16.397940008672037	(conditional on Round 4 SNPs)	0.057	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.79	NA	0.057
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels (conditioned on lead SNPs)	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer)	NA	NA	NA	KLK3	NA	NA	NA	NA	NA	NA	rs266868-?	rs266868	0	266868	intron_variant	TRUE	0.71	1e-14	14	(conditional on Round 3 SNPs)	0.046	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004094	Genome-wide genotyping array	0.71	NA	0.046
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	1q25.1	1	173182897	TNFSF18, TNFSF4	GOT2P2 - TNFSF4	ENSG00000230849	ENSG00000117586	NA	40547	834	rs6691738-?	rs6691738	0	6691738	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	NA	1.0604454	[1.04-1.08]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.0604454	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Asthma	28,399 European ancestry cases, 128,843 European ancestry controls	NA	1p36.22	1	10497194	PEX14	PEX14	NA	NA	ENSG00000142655	NA	NA	rs662064-?	rs662064	0	662064	intron_variant	FALSE	NR	3e-8	7.522878745280337	NA	1.0615711	[1.04-1.08]	Illumina [13747813] (imputed)	N	asthma	http://www.ebi.ac.uk/efo/EFO_0000270	GCST003987	Genome-wide genotyping array	NA	1.0615711	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	9q22.33	9	97779894	FOXE1, XPA	PTCSC2	NA	NA	ENSG00000236130	NA	NA	rs10759927-?	rs10759927	0	10759927	intron_variant	FALSE	NR	1e-89	89	NA	1.313	[1.278-1.349]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.313	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	6p21.32	6	32658715	HLA-DQA1, HLA-DQB1	HLA-DQA1 - HLA-DQB1	ENSG00000196735	ENSG00000206237	NA	11653	752	rs9273370-?	rs9273370	0	9273370	regulatory_region_variant	TRUE	NR	5e-34	33.30102999566398	NA	1.1737089	[1.14-1.20]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.1737089	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	1p13.2	1	113834946	PTPN22	PTPN22	NA	NA	ENSG00000134242	NA	NA	rs2476601-?	rs2476601	0	2476601	missense_variant	FALSE	NR	2e-31	30.69897000433602	NA	1.2722646	[1.22-1.32]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.2722646	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	12q24.12	12	111472415	ATXN2	ATXN2	NA	NA	ENSG00000204842	NA	NA	rs10774625-?	rs10774625	0	10774625	intron_variant	FALSE	NR	1e-26	26	NA	1.1428571	[1.11-1.17]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.1428571	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	5q13.3	5	77232197	PDE8B	PDE8B	NA	NA	ENSG00000113231	NA	NA	rs1479567-?	rs1479567	0	1479567	intron_variant	FALSE	NR	1e-23	23	NA	1.1363636	[1.11-1.16]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.1363636	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	1p13.3	1	107793911	VAV3	VAV3	NA	NA	ENSG00000134215	NA	NA	rs17020055-?	rs17020055	0	17020055	intron_variant	FALSE	NR	3e-22	21.522878745280337	NA	1.225	[1.18-1.28]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.225	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	4q31.23	4	148710641	NR3C2	ATP5MGP4 - NA	ENSG00000225176	NA	NA	6809	NA	rs76342258-?	rs76342258	0	76342258	intron_variant	TRUE	NR	8e-18	17.096910013008056	NA	1.1494253	[1.11-1.19]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.1494253	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	2q33.2	2	203874196	CTLA4, ICOS	CTLA4 - ICOS	ENSG00000163599	ENSG00000163600	NA	231	62567	rs3087243-?	rs3087243	0	3087243	intergenic_variant	TRUE	NR	1e-15	15	NA	1.105	[1.08-1.14]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.105	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	6q24.3	6	148193165	SAMD5, SASH1	SAMD5 - SASH1	ENSG00000203727	ENSG00000111961	NA	455618	79139	rs6914622-?	rs6914622	0	6914622	regulatory_region_variant	TRUE	NR	1e-14	14	NA	1.109	[1.08-1.14]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.109	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	2p25.3	2	1403856	TPO, SNTG2	TPO	NA	NA	ENSG00000115705	NA	NA	rs11675342-?	rs11675342	0	11675342	intron_variant	FALSE	NR	6e-14	13.221848749616356	NA	1.099	[1.08-1.12]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.099	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	6q27	6	165633546	PDE10A	PDE10A	NA	NA	ENSG00000112541	NA	NA	rs1079418-?	rs1079418	0	1079418	intron_variant	FALSE	NR	9e-12	11.045757490560675	NA	1.0964912	[1.07-1.13]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.0964912	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	NA	NA	NA	C1QTNF6	NA	NA	NA	NA	NA	NA	chr22:37583733-?	chr22:37583733	0	NA	NA	TRUE	NR	1e-10	10	NA	1.085	[1.059-1.113]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.085	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	10q24.2	10	99523573	GOT1, NKX2-3	GOT1 - LINC01475	ENSG00000120053	ENSG00000257582	NA	92949	2777	rs10748781-?	rs10748781	0	10748781	intergenic_variant	TRUE	NR	1e-10	10	NA	1.088	[1.060-1.116]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.088	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	6p21.1	6	43837765	VEGFA, C6orf223	VEGFA - LINC02537	ENSG00000112715	ENSG00000283215	NA	51278	7113	rs10223666-?	rs10223666	0	10223666	intron_variant	TRUE	NR	5e-10	9.301029995663981	NA	1.0905125	[1.06-1.12]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.0905125	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	20p11.21	20	22649878	FOXA2, SSTR4	LNCNEF - LINC01747	ENSG00000237396	ENSG00000230400	NA	42361	18602	rs201295667-?	rs201295667	0	201295667	intergenic_variant	TRUE	NR	5e-10	9.301029995663981	NA	1.1086475	[1.07-1.15]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.1086475	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	8p12	8	32575431	NRG1	NRG1	NA	NA	ENSG00000157168	NA	NA	rs2466075-?	rs2466075	0	2466075	intron_variant	FALSE	NR	6e-10	9.221848749616356	NA	1.08	[1.05-1.11]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.08	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	2q35	2	216763707	IGFBP5, TNP1	IGFBP5 - RPL31P14	ENSG00000115461	ENSG00000237930	NA	68158	22067	rs1861628-?	rs1861628	0	1861628	intron_variant	TRUE	NR	6e-9	8.221848749616356	NA	1.09	[1.05-1.12]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.09	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	8q24.22	8	132882609	TG	TG	NA	NA	ENSG00000042832	NA	NA	rs121912648-?	rs121912648	0	121912648	stop_gained	FALSE	NR	7e-9	8.154901959985743	NA	3.66	[2.44-5.56]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	3.66	NA
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q12	19	31614073	THEG5	LINC02841 - RNA5SP471	ENSG00000267407	ENSG00000252780	NA	59270	41283	rs11084596-T	rs11084596	0	11084596	regulatory_region_variant	TRUE	0.61	1e-15	15	NA	0.0475551	[0.036-0.059] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.61	NA	0.0475551
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q13.33	19	50858501	KLK3	KLK3	NA	NA	ENSG00000142515	NA	NA	rs17632542-T	rs17632542	0	17632542	missense_variant	FALSE	0.92	0	339.69897000433605	NA	0.435333	[0.41-0.46] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.92	NA	0.435333
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	Xp22.13	X	17802225	RAI2	RAI2	NA	NA	ENSG00000131831	NA	NA	rs16980679-G	rs16980679	0	16980679	intron_variant	FALSE	0.95	3e-15	14.522878745280337	NA	0.0765243	[0.058-0.096] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.95	NA	0.0765243
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	Xp11.21	X	55910389	RRAGB	NA - GOT2P6	NA	ENSG00000214745	NA	NA	50819	rs10855058-A	rs10855058	0	10855058	intron_variant	TRUE	0.3	1e-8	8	NA	0.0254562	[0.017-0.034] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.3	NA	0.0254562
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	4q31.22	4	145953076	ZNF827	ZNF827 - Y_RNA	ENSG00000151612	ENSG00000199964	NA	14253	5052	rs56935123-AT	rs56935123	0	56935123	intergenic_variant	TRUE	0.45	4e-9	8.397940008672037	NA	0.0351137	[0.023-0.047] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.45	NA	0.0351137
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	7p15.1	7	27936944	JAZF1	JAZF1	NA	NA	ENSG00000153814	NA	NA	rs10486567-G	rs10486567	0	10486567	intron_variant	FALSE	0.76	4e-19	18.397940008672037	NA	0.0575792	[0.045-0.07] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.76	NA	0.0575792
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	9q33.2	9	120881149	PHF19	PHF19	NA	NA	ENSG00000119403	NA	NA	rs59482735-T	rs59482735	0	59482735	intron_variant	FALSE	0.32	4e-9	8.397940008672037	NA	0.0363711	[0.024-0.048] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.32	NA	0.0363711
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	NA	NA	NA	FGFR2	NA	NA	NA	NA	NA	NA	rs10886902-C	rs10886902	0	10886902	regulatory_region_variant	TRUE	0.24	2e-53	52.69897000433602	NA	0.100774	[0.088-0.114] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.24	NA	0.100774
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	13q14.3	13	50513307	DLEU1	DLEU1	NA	NA	ENSG00000176124	NA	NA	rs202346-A	rs202346	0	202346	intron_variant	FALSE	0.25	3e-22	21.522878745280337	NA	0.061691	[0.049-0.074] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.25	NA	0.061691
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	17q12	17	37737784	HNF1B	HNF1B, HNF1B	NA	NA	ENSG00000276194, ENSG00000275410	NA	NA	rs11263761-A	rs11263761	0	11263761	intron_variant	FALSE	0.51	6e-20	19.221848749616356	NA	0.0515111	[0.04-0.063] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.51	NA	0.0515111
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	1p22.3	1	87724354	LMO4	PKN2-AS1	NA	NA	ENSG00000237505	NA	NA	rs6662386-C	rs6662386	0	6662386	intron_variant	FALSE	0.44	7e-20	19.154901959985743	NA	0.051711	[0.041-0.063] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.44	NA	0.051711
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	Xp22.11	X	24041058	EIF2S3, KLHL15	KLHL15 - EIF2S3	ENSG00000174010	ENSG00000130741	NA	13872	13888	rs6627995-T	rs6627995	0	6627995	intergenic_variant	TRUE	0.33	1e-13	13	NA	0.0343829	[0.025-0.043] unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.33	NA	0.0343829
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	10q26.13	10	121425789	FGFR2, WDR11, 7SK	RN7SKP167 - FGFR2; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10749415-G; rs200367988-G; rs10886902-T	rs10749415; rs200367988; rs10886902	0	NA	intergenic_variant; intergenic_variant; regulatory_region_variant	NA	0.025	3e-11	10.522878745280337	NA	0.168	unit decrease	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.025	NA	0.168
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	10q26.13	10	121425789	FGFR2, WDR11, 7SK	RN7SKP167 - FGFR2; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10749415-A; rs200367988-A; rs10886902-T	rs10749415; rs200367988; rs10886902	0	NA	intergenic_variant; intergenic_variant; regulatory_region_variant	NA	0.148	4e-18	17.397940008672037	NA	0.091	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.148	NA	0.091
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	10q26.13	10	121425789	FGFR2, WDR11, 7SK	RN7SKP167 - FGFR2; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10749415-A; rs200367988-G; rs10886902-T	rs10749415; rs200367988; rs10886902	0	NA	intergenic_variant; intergenic_variant; regulatory_region_variant	NA	0.491	1e-35	35	NA	0.089	unit decrease	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.491	NA	0.089
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	10q26.13	10	121425789	FGFR2, WDR11, 7SK	RN7SKP167 - FGFR2; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs10749415-A; rs200367988-A; rs10886902-C	rs10749415; rs200367988; rs10886902	0	NA	intergenic_variant; intergenic_variant; regulatory_region_variant	NA	0.078	4e-43	42.39794000867204	NA	0.206	unit decrease	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.078	NA	0.206
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q13.33	19;19	50870023;50858501	KLK3, KLK2	KLK2; No mapped genes; No mapped genes; KLK3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2739472-T; rs6070-T; rs11665748-G; rs17632542-G; rs266849-C; rs266868-G; rs61752561-G	rs2739472; rs6070; rs11665748; rs17632542; rs266849; rs266868; rs61752561	0	NA	intron_variant; non_coding_transcript_exon_variant; intergenic_variant; missense_variant; intron_variant; intron_variant; missense_variant	NA	0.042	9e-186	185.04575749056067	NA	0.506	unit decrease	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.042	NA	0.506
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q13.33	19;19	50870023;50858501	KLK3, KLK2	KLK2; No mapped genes; No mapped genes; KLK3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2739472-C; rs6070-T; rs11665748-G; rs17632542-G; rs266849-T; rs266868-A; rs61752561-A	rs2739472; rs6070; rs11665748; rs17632542; rs266849; rs266868; rs61752561	0	NA	intron_variant; non_coding_transcript_exon_variant; intergenic_variant; missense_variant; intron_variant; intron_variant; missense_variant	NA	0.204	2e-111	110.69897000433602	NA	0.211	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.204	NA	0.211
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q13.33	19;19	50870023;50858501	KLK3, KLK2	KLK2; No mapped genes; No mapped genes; KLK3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2739472-C; rs6070-A; rs11665748-G; rs17632542-G; rs266849-T; rs266868-A; rs61752561-A	rs2739472; rs6070; rs11665748; rs17632542; rs266849; rs266868; rs61752561	0	NA	intron_variant; non_coding_transcript_exon_variant; intergenic_variant; missense_variant; intron_variant; intron_variant; missense_variant	NA	0.107	8e-17	16.096910013008056	NA	0.109	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.107	NA	0.109
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q13.33	19;19	50870023;50858501	KLK3, KLK2	KLK2; No mapped genes; No mapped genes; KLK3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2739472-T; rs6070-A; rs11665748-G; rs17632542-G; rs266849-C; rs266868-G; rs61752561-G	rs2739472; rs6070; rs11665748; rs17632542; rs266849; rs266868; rs61752561	0	NA	intron_variant; non_coding_transcript_exon_variant; intergenic_variant; missense_variant; intron_variant; intron_variant; missense_variant	NA	0.01	1e-85	85	NA	0.856	unit decrease	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.01	NA	0.856
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q13.33	19;19	50870023;50858501	KLK3, KLK2	KLK2; No mapped genes; No mapped genes; KLK3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2739472-C; rs6070-T; rs11665748-A; rs17632542-G; rs266849-T; rs266868-A; rs61752561-A	rs2739472; rs6070; rs11665748; rs17632542; rs266849; rs266868; rs61752561	0	NA	intron_variant; non_coding_transcript_exon_variant; intergenic_variant; missense_variant; intron_variant; intron_variant; missense_variant	NA	0.059	4e-9	8.397940008672037	NA	0.1	unit increase	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.059	NA	0.1
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q13.33	19;19	50870023;50858501	KLK3, KLK2	KLK2; No mapped genes; No mapped genes; KLK3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2739472-C; rs6070-T; rs11665748-A; rs17632542-A; rs266849-T; rs266868-A; rs61752561-A	rs2739472; rs6070; rs11665748; rs17632542; rs266849; rs266868; rs61752561	0	NA	intron_variant; non_coding_transcript_exon_variant; intergenic_variant; missense_variant; intron_variant; intron_variant; missense_variant	NA	0.024	1e-7	7	NA	0.124	unit decrease	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.024	NA	0.124
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q13.33	19;19	50870023;50858501	KLK3, KLK2	KLK2; No mapped genes; No mapped genes; KLK3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2739472-T; rs6070-T; rs11665748-G; rs17632542-G; rs266849-T; rs266868-G; rs61752561-G	rs2739472; rs6070; rs11665748; rs17632542; rs266849; rs266868; rs61752561	0	NA	intron_variant; non_coding_transcript_exon_variant; intergenic_variant; missense_variant; intron_variant; intron_variant; missense_variant	NA	0.029	8e-10	9.096910013008056	NA	0.153	unit decrease	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.029	NA	0.153
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q13.33	19;19	50870023;50858501	KLK3, KLK2	KLK2; No mapped genes; No mapped genes; KLK3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2739472-T; rs6070-A; rs11665748-G; rs17632542-G; rs266849-T; rs266868-G; rs61752561-G	rs2739472; rs6070; rs11665748; rs17632542; rs266849; rs266868; rs61752561	0	NA	intron_variant; non_coding_transcript_exon_variant; intergenic_variant; missense_variant; intron_variant; intron_variant; missense_variant	NA	0.02	3e-11	10.522878745280337	NA	0.201	unit decrease	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.02	NA	0.201
2017-05-25	28139693	Hoffmann TJ	2017-01-31	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Prostate-specific antigen levels	28,503 European ancestry individuals	2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals	19q13.33	19;19	50870023;50858501	KLK3, KLK2	KLK2; No mapped genes; No mapped genes; KLK3; No mapped genes; No mapped genes; No mapped genes	NA	NA	NA	NA	NA	rs2739472-C; rs6070-T; rs11665748-G; rs17632542-G; rs266849-C; rs266868-A; rs61752561-G	rs2739472; rs6070; rs11665748; rs17632542; rs266849; rs266868; rs61752561	0	NA	intron_variant; non_coding_transcript_exon_variant; intergenic_variant; missense_variant; intron_variant; intron_variant; missense_variant	NA	0.011	2e-45	44.69897000433602	NA	0.494	unit decrease	Affymetrix [10109774] (imputed)	N	prostate specific antigen measurement	http://www.ebi.ac.uk/efo/EFO_0004624	GCST004093	Genome-wide genotyping array	0.011	NA	0.494
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	11q24.2	11	127398707	Intergenic	LINC02712 - RN7SKP121	ENSG00000273409	ENSG00000222774	NA	61674	7321	rs190169131-G	rs190169131	0	190169131	intergenic_variant	TRUE	0.998	1e-6	6	(AA)	0.315	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.998	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q12	4	56814244	SPINK2	SPINK2	NA	NA	ENSG00000128040	NA	NA	rs190972371-C	rs190972371	0	190972371	intron_variant	FALSE	0.998	1e-6	6	(AA)	0.22	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.998	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	19q13.42	19	55224110	Intergenic	PTPRH - TMEM86B	ENSG00000080031	ENSG00000180089	NA	14604	2528	rs139704751-T	rs139704751	0	139704751	intergenic_variant	TRUE	1.0	1e-6	6	(AA)	0.59	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	14q32.13	14	94206394	PPP4R4	PPP4R4	NA	NA	ENSG00000119698	NA	NA	rs112458284-C	rs112458284	0	112458284	intron_variant	FALSE	0.993	1e-6	6	(AA)	0.109	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.993	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	10q22.1	10	70120545	AIFM2	AIFM2	NA	NA	ENSG00000042286	NA	NA	rs139479025-C	rs139479025	0	139479025	missense_variant	FALSE	0.999	1e-6	6	(AA)	0.374	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	8p23.2	8	5426774	Intergenic	NA - RPL23AP54	NA	ENSG00000240486	NA	NA	49774	rs141088253-G	rs141088253	0	141088253	intergenic_variant	TRUE	0.999	1e-6	6	(AA)	0.384	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q21.3	15	57808394	Intergenic	POLR2M - NA	ENSG00000255529	NA	NA	25632	NA	rs145330511-T	rs145330511	0	145330511	intergenic_variant	TRUE	0.995	1e-6	6	(AA)	0.127	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.995	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	6p21.2	6	38283599	BTBD9	BTBD9	NA	NA	ENSG00000183826	NA	NA	rs77928651-A	rs77928651	0	77928651	intron_variant	FALSE	0.999	1e-6	6	(AA)	0.254	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	1p21.1	1	104948564	Intergenic	NA	NA	NA	NA	NA	NA	rs187226391-C	rs187226391	0	187226391	intergenic_variant	TRUE	0.998	1e-6	6	(AA)	0.228	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.998	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	15q21.3	15	57809666	Intergenic	POLR2M - NA	ENSG00000255529	NA	NA	26904	NA	rs140949321-A	rs140949321	1	112996782	intergenic_variant	TRUE	0.994	1e-6	6	(AA)	0.127	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.994	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	2q37.1	2	230447662	SP100	SP100	NA	NA	ENSG00000067066	NA	NA	rs141521978-T	rs141521978	0	141521978	intron_variant	FALSE	0.996	1e-6	6	(AA)	0.168	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.996	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	12q21.1	12	75180543	KCNC2	KCNC2	NA	NA	ENSG00000166006	NA	NA	rs186586221-C	rs186586221	0	186586221	intron_variant	FALSE	0.999	1e-6	6	(AA)	0.332	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	12q21.33	12	91093740	Intergenic	KERA - LUM	ENSG00000139330	ENSG00000139329	NA	35716	8889	rs187607716-G	rs187607716	0	187607716	intergenic_variant	TRUE	1.0	1e-6	6	(AA)	0.451	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97565435	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs139367725-C	rs139367725	1	9993236	intron_variant	FALSE	0.69	1e-6	6	(AA)	0.017	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.69	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	9p21.3	9	25458903	Intergenic	NA	NA	NA	NA	NA	NA	rs183397371-C	rs183397371	0	183397371	intergenic_variant	TRUE	0.998	1e-6	6	(AA)	0.231	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.998	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	18q12.3	18	41458077	Intergenic	NA - KC6	NA	ENSG00000267313	NA	NA	7706	rs184167040-A	rs184167040	0	184167040	intron_variant	TRUE	1.0	1e-6	6	(AA)	0.544	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	4q22.3	4	97635631	C4orf37	STPG2	NA	NA	ENSG00000163116	NA	NA	rs148460633-G	rs148460633	0	148460633	intron_variant	FALSE	0.63	1e-6	6	(AA)	0.017	unit decrease	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.63	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	3q25.32	3	159127152	IQCJ	IQCJ-SCHIP1, IQCJ	NA	NA	ENSG00000283154, ENSG00000214216	NA	NA	rs138869894-A	rs138869894	0	138869894	intron_variant	FALSE	1.0	1e-6	6	(AA)	0.576	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	1	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	17q25.1	17	73947436	Intergenic	NA - LINC02074	NA	ENSG00000266357	NA	NA	96016	rs111926416-A	rs111926416	0	111926416	intron_variant	TRUE	0.999	1e-6	6	(AA)	0.33	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	7p21.3	7	8411282	Intergenic	NA - NXPH1	NA	ENSG00000122584	NA	NA	22327	rs75890985-C	rs75890985	0	75890985	intergenic_variant	TRUE	0.954	1e-6	6	(AA)	0.039	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.954	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	9p21.1	9	30973109	Intergenic	FTLP4 - HSPA8P17	ENSG00000214020	ENSG00000228557	NA	37132	14976	rs141510725-G	rs141510725	0	141510725	intergenic_variant	TRUE	0.999	1e-6	6	(AA)	0.32	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	9p21.1	9	30973700	Intergenic	FTLP4 - HSPA8P17	ENSG00000214020	ENSG00000228557	NA	37723	14385	rs138792676-A	rs138792676	0	138792676	intergenic_variant	TRUE	0.999	1e-6	6	(AA)	0.32	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	2p12	2	81893393	Intergenic	NA - RN7SL201P	NA	ENSG00000242118	NA	NA	73686	rs78797065-C	rs78797065	0	78797065	intergenic_variant	TRUE	0.997	1e-6	6	(AA)	0.176	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.997	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	9p21.1	9	30972357	Intergenic	FTLP4 - HSPA8P17	ENSG00000214020	ENSG00000228557	NA	36380	15728	rs184676284-A	rs184676284	0	184676284	intergenic_variant	TRUE	0.999	1e-6	6	(AA)	0.32	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.999	NA	NA
2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1/FVC ratio	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals	NA	8p23.1	8	9416866	Intergenic	RNU6-526P - NA	ENSG00000201815	NA	NA	45671	NA	rs142487520-C	rs142487520	0	142487520	intron_variant	TRUE	0.998	1e-6	6	(AA)	0.204	unit increase	Illumina [NR] (imputed)	N	response to bronchodilator, FEV/FEC ratio	http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713	GCST003264	Genome-wide genotyping array	0.998	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	19p13.2	19	7222821	INSR	INSR	NA	NA	ENSG00000171105	NA	NA	rs7508679-?	rs7508679	0	7508679	intron_variant	FALSE	NR	1e-7	7	NA	1.0695187	[1.04-1.10]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.0695187	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	6q15	6	90266280	BACH2	BACH2	NA	NA	ENSG00000112182	NA	NA	rs661713-?	rs661713	0	661713	intron_variant	FALSE	NR	2e-7	6.698970004336019	NA	1.0695187	[1.04-1.10]	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	1.0695187	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Hypothyroidism	17,558 European ancestry cases, 117,083 European ancestry controls	NA	1p34.3	1	37814315	MTF1	MTF1	NA	NA	ENSG00000188786	NA	NA	rs3748682-?	rs3748682	0	3748682	3_prime_UTR_variant	FALSE	NR	7e-6	5.154901959985743	NA	NA	NA	Illumina [13676411] (imputed)	N	hypothyroidism	http://www.ebi.ac.uk/efo/EFO_0004705	GCST003988	Genome-wide genotyping array	NA	NA	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	1p12	1	118909877	TBX15	TBX15	NA	NA	ENSG00000092607	NA	NA	rs1766786-?	rs1766786	0	1766786	intron_variant	FALSE	NR	2e-13	12.698970004336019	NA	1.1750882	[1.13-1.23]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1750882	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	9p22.2	9	16958465	BNC2, CNTLN	BNC2 - RN7SL720P	ENSG00000173068	ENSG00000241152	NA	87622	95436	rs10962767-?	rs10962767	0	10962767	intron_variant	TRUE	NR	2e-13	12.698970004336019	NA	1.1111112	[1.08-1.14]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1111112	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	13q12.11	13	22139569	FGF9	LINC00540	NA	NA	ENSG00000276476	NA	NA	rs73168105-?	rs73168105	0	73168105	intron_variant	FALSE	NR	3e-13	12.522878745280337	NA	1.149	[1.107-1.193]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.149	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	2p21	2	41954539	C2orf91, PKDCC	C2orf91	NA	NA	ENSG00000205086	NA	NA	rs6740960-?	rs6740960	0	6740960	intron_variant	FALSE	NR	4e-13	12.397940008672037	NA	1.117	[1.084-1.151]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.117	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	15q26.3	15	100666433	ASB7, ALDH1A3	ASB7 - NA	ENSG00000183475	NA	NA	14732	NA	rs7167736-?	rs7167736	0	7167736	regulatory_region_variant	TRUE	NR	9e-13	12.045757490560675	NA	1.1363636	[1.1-1.18]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1363636	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	5q14.2	5	82828371	ATP6AP1L, TMEM167A	RPL5P16 - MIR3977	ENSG00000240411	ENSG00000283359	NA	49785	11784	rs10078545-?	rs10078545	0	10078545	intergenic_variant	TRUE	NR	1e-12	12	NA	1.112	[1.080-1.145]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.112	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	3q25.32	3	158110533	RSRC1	RSRC1	NA	NA	ENSG00000174891	NA	NA	rs11713363-?	rs11713363	0	11713363	5_prime_UTR_variant	FALSE	NR	2e-12	11.698970004336019	NA	1.1235955	[1.09-1.16]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1235955	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	5q13.3	5	74187296	ARHGEF28, ENC1	LINC01331	NA	NA	ENSG00000248673	NA	NA	rs199880074-?	rs199880074	0	199880074	intron_variant	FALSE	NR	5e-12	11.301029995663981	NA	1.1198208	[1.08-1.16]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1198208	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	17q24.3	17	71126965	KCNJ2, SOX9	CASC17	NA	NA	ENSG00000260785	NA	NA	rs56347314-?	rs56347314	0	56347314	intron_variant	FALSE	NR	5e-12	11.301029995663981	NA	1.108	[1.076-1.140]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.108	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	17p13.1	17	7549435	TNFSF12, TNFSF13	TNFSF12-TNFSF13, TNFSF12	NA	NA	ENSG00000248871, ENSG00000239697	NA	NA	rs80067372-?	rs80067372	0	80067372	non_coding_transcript_exon_variant	FALSE	NR	1e-11	11	NA	1.115	[1.080-1.150]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.115	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	4q34.1	4	173456853	SCRG1, HAND2	RNU6-1096P - HAND2	ENSG00000252898	ENSG00000164107	NA	10149	68116	rs12505328-?	rs12505328	0	12505328	intergenic_variant	TRUE	NR	2e-11	10.698970004336019	NA	1.106	[1.074-1.139]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.106	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	1q21.3	1	155060832	ADAM15	ADAM15	NA	NA	ENSG00000143537	NA	NA	rs11589479-?	rs11589479	0	11589479	splice_region_variant	FALSE	NR	5e-11	10.301029995663981	NA	1.131	[1.090-1.173]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.131	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	3q26.32	3	177584204	TBL1XR1, KCNMB2	LINC00578	NA	NA	ENSG00000228221	NA	NA	rs2133593-?	rs2133593	0	2133593	intron_variant	FALSE	NR	7e-11	10.154901959985743	NA	1.1061947	[1.07-1.14]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1061947	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	8q24.13	8	122089504	HAS2, ZHX2	HAS2-AS1 - MRPS36P3	ENSG00000248690	ENSG00000253814	NA	95319	1976	rs12541121-?	rs12541121	0	12541121	intron_variant	TRUE	NR	5e-10	9.301029995663981	NA	1.095	[1.064-1.127]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.095	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	14q32.13	14	95013552	GSC, DICER1	LINC02279 - DICER1	ENSG00000258933	ENSG00000100697	NA	50576	72676	rs7161418-?	rs7161418	0	7161418	intergenic_variant	TRUE	NR	1e-9	9	NA	1.106	[1.070-1.143]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.106	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	1q23.1	1	156969383	ARHGEF11	ARHGEF11	NA	NA	ENSG00000132694	NA	NA	rs1336149-?	rs1336149	0	1336149	intron_variant	FALSE	NR	2e-9	8.698970004336019	NA	1.093	[1.062-1.125]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.093	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	8p12	8	32495664	NRG1	NRG1	NA	NA	ENSG00000157168	NA	NA	rs2347498-?	rs2347498	0	2347498	intron_variant	FALSE	NR	2e-9	8.698970004336019	NA	1.0928961	[1.06-1.13]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.0928961	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	10q22.3	10	76390527	C10orf11	LRMDA	NA	NA	ENSG00000148655	NA	NA	rs11001765-?	rs11001765	0	11001765	intron_variant	FALSE	NR	4e-9	8.397940008672037	NA	1.1312217	[1.09-1.18]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1312217	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	3q24	3	148111690	ZIC1, AGTR1	LINC02032 - HNRNPA1P20	ENSG00000241131	ENSG00000205412	NA	22556	54654	rs12495832-?	rs12495832	0	12495832	intron_variant	TRUE	NR	4e-9	8.397940008672037	NA	1.1494253	[1.1-1.2]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.1494253	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	12q14.3	12	66003386	HMGA2, LLPH	HMGA2 - MIR6074	ENSG00000149948	ENSG00000276878	NA	37095	20234	rs141753469-?	rs141753469	0	141753469	regulatory_region_variant	TRUE	NR	6e-9	8.221848749616356	NA	1.111	[1.072-1.151]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.111	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	4q28.1	4	126033497	FAT4	NA - LINC02379	NA	ENSG00000251649	NA	NA	30631	rs145365164-?	rs145365164	0	145365164	intergenic_variant	TRUE	NR	1e-8	8	NA	1.109	[1.070-1.148]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.109	NA
2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Chin dimples	58,032 European ancestry cases, 13,457 European ancestry controls	NA	5q33.2	5	154488702	HAND1, LARP1	HAND1 - CIR1P1	ENSG00000113196	ENSG00000253146	NA	10475	70606	rs4958741-?	rs4958741	0	4958741	intergenic_variant	TRUE	NR	1e-8	8	NA	1.108	[1.069-1.147]	Illumina [13537761] (imputed)	N	chin morphology measurement	http://www.ebi.ac.uk/efo/EFO_0007842	GCST003989	Genome-wide genotyping array	NA	1.108	NA
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	19q13.32	19	44886339	APOE, APOC1, APOC2	NECTIN2	NA	NA	ENSG00000130202	NA	NA	rs7254892-A	rs7254892	0	7254892	intron_variant	FALSE	0.07	4e-22	21.397940008672037	(BMI unadjusted)	0.408	[0.33-0.49] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.07	NA	0.408
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	1p13.3	1	109279544	SORT1	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222	NA	3793	12	rs599839-A	rs599839	0	599839	intergenic_variant	TRUE	0.93	2e-17	16.69897000433602	(BMI unadjusted)	0.162	[0.13-0.2] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.93	NA	0.162
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	5q13.3	5	75513055	HMGCR	POLK	NA	NA	ENSG00000122008	NA	NA	rs4604177-T	rs4604177	0	4604177	intron_variant	FALSE	0.53	4e-16	15.397940008672037	(BMI unadjusted)	0.081	[0.061-0.101] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.53	NA	0.081
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	16q22.2	16	71978873	PKD1L3	PKD1L3	NA	NA	ENSG00000277481	NA	NA	rs1122531-T	rs1122531	0	1122531	intron_variant	FALSE	0.71	1e-13	13	(BMI unadjusted)	0.081	[0.059-0.103] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.71	NA	0.081
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	18q21.1	18	49592028	LIPG	LIPG	NA	NA	ENSG00000101670	NA	NA	rs9958734-T	rs9958734	0	9958734	3_prime_UTR_variant	FALSE	0.62	3e-13	12.522878745280337	(BMI unadjusted)	0.11	[0.081-0.139] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.62	NA	0.11
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	2p24.1	2	20982585	APOB	NA - APOB	NA	ENSG00000084674	NA	NA	18844	rs10172650-A	rs10172650	0	10172650	intergenic_variant	TRUE	0.13	3e-13	12.522878745280337	(BMI unadjusted)	0.102	[0.075-0.129] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.13	NA	0.102
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	9q34.2	9	133278724	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	2700	23746	rs579459-T	rs579459	0	579459	intergenic_variant	TRUE	0.78	7e-13	12.154901959985743	(BMI unadjusted)	0.082	[0.06-0.104] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.78	NA	0.082
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	8q24.13	8	125476008	TRIB1	TRIB1 - NA	ENSG00000173334	NA	NA	37605	NA	rs2980869-T	rs2980869	0	2980869	intron_variant	TRUE	0.56	8e-13	12.096910013008056	(BMI unadjusted)	0.07	[0.05-0.09] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.56	NA	0.07
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	6q23.3	6	135097497	HBS1L	HBS1L	NA	NA	ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	FALSE	0.29	1e-11	11	(BMI unadjusted)	0.077	[0.055-0.099] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.29	NA	0.077
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	19p13.2	19	11223619	LDLR	DOCK6	NA	NA	ENSG00000130158	NA	NA	rs4804155-C	rs4804155	0	4804155	intron_variant	FALSE	0.75	7e-11	10.154901959985743	(BMI unadjusted)	0.074	[0.052-0.096] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.75	NA	0.074
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	9q31.1	9	104902020	ABCA1	ABCA1	NA	NA	ENSG00000165029	NA	NA	rs1883025-T	rs1883025	0	1883025	intron_variant	FALSE	0.26	1e-9	9	(BMI unadjusted)	0.067	[0.045-0.089] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.26	NA	0.067
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	NA	NA	NA	LIPC	NA	NA	NA	NA	NA	NA	rs6494005-A	rs6494005	0	6494005	non_coding_transcript_exon_variant	TRUE	0.75	3e-9	8.522878745280337	(BMI unadjusted)	0.024	[0.016-0.032] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.75	NA	0.024
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	2p23.3	2	27520287	GCKR	GCKR	NA	NA	ENSG00000084734	NA	NA	rs780092-A	rs780092	0	780092	intron_variant	FALSE	0.67	6e-9	8.221848749616356	(BMI unadjusted)	0.058	[0.038-0.078] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.67	NA	0.058
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	6q25.3	6	160085430	LPA	IGF2R	NA	NA	ENSG00000197081	NA	NA	rs2297363-A	rs2297363	0	2297363	intron_variant	FALSE	0.26	2e-8	7.698970004336019	(BMI unadjusted)	0.022	[0.014-0.03] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.26	NA	0.022
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	16q13	16	56981633	CETP	CETP	NA	NA	ENSG00000087237	NA	NA	rs1800774-T	rs1800774	0	1800774	intron_variant	FALSE	0.12	2e-6	5.698970004336019	(BMI adjusted)	0.069	[0.042-0.096] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.12	NA	0.069
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Total cholesterol levels	22,814 East Asian ancestry individuals	57,490 East Asian ancestry individuals	1p32.3	1	55063514	PCSK9	PCSK9	NA	NA	ENSG00000169174	NA	NA	rs505151-A	rs505151	0	505151	missense_variant	FALSE	0.94	4e-6	5.3979400086720375	(BMI unadjusted)	0.102	[0.059-0.145] unit decrease	Affymetrix, Illumina [~ 2400000] (imputed)	N	total cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004574	GCST004231	Genome-wide genotyping array	0.94	NA	0.102
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	1p13.3	1	109279544	SORT1	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222	NA	3793	12	rs599839-A	rs599839	0	599839	intergenic_variant	TRUE	0.782	4e-289	288.39794000867204	(Trans-ethnic initial)	0.16	[0.15-0.17] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.782	NA	0.16
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	19q13.32	19	44908822	APOC1, APOE, APOC2	APOE	NA	NA	ENSG00000130203	NA	NA	rs7412-T	rs7412	0	7412	missense_variant	FALSE	0.066	2e-286	285.69897000433605	(Trans-ethnic initial)	0.59	[0.57-0.61] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.066	NA	0.59
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	2p24.1	2	21041028	APOB	APOB	NA	NA	ENSG00000084674	NA	NA	rs1367117-A	rs1367117	0	1367117	missense_variant	FALSE	0.288	2e-179	178.69897000433602	(Trans-ethnic initial)	0.119	[0.11-0.13] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.288	NA	0.119
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	19q13.32	19	44912383	APOE, APOC1, APOC2	APOE - APOC1	ENSG00000130203	ENSG00000130208	NA	2990	1864	rs445925-A	rs445925	0	445925	non_coding_transcript_exon_variant	TRUE	0.09	1e-129	129	(Asian initial, BMI unadjusted)	0.523	[0.48-0.56] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.09	NA	0.523
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	5q13.3	5	75360714	HMGCR	HMGCR, CERT1	NA	NA	ENSG00000113161, ENSG00000113163	NA	NA	rs12916-T	rs12916	0	12916	3_prime_UTR_variant	FALSE	0.569	3e-95	94.52287874528034	(Trans-ethnic initial)	0.0733	[0.066-0.081] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.569	NA	0.0733
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	8q24.13	8	125478730	TRIB1	TRIB1 - NA	ENSG00000173334	NA	NA	40327	NA	rs2954029-A	rs2954029	0	2954029	intron_variant	TRUE	0.532	2e-56	55.69897000433602	(Trans-ethnic initial)	0.0564	[0.049-0.063] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.532	NA	0.0564
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	9q34.2	9	133278724	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000199964	NA	2700	23746	rs579459-T	rs579459	0	579459	intergenic_variant	TRUE	0.785	2e-51	50.69897000433602	(Trans-ethnic initial)	0.0665	[0.058-0.075] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.785	NA	0.0665
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	19p13.11	19	19296909	CILP2	SUGP1	NA	NA	ENSG00000105705	NA	NA	rs10401969-T	rs10401969	0	10401969	intron_variant	FALSE	0.929	6e-51	50.221848749616356	(Trans-ethnic initial)	0.118	[0.1-0.13] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.929	NA	0.118
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	11q12.2	11	61830500	FADS1, FADS2, FADS3	FADS2	NA	NA	ENSG00000134824	NA	NA	rs1535-A	rs1535	0	1535	intron_variant	FALSE	0.637	5e-45	44.30102999566398	(Trans-ethnic initial)	0.0529	[0.045-0.06] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.637	NA	0.0529
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q21.21	4	80263187	PRDM8, FGF5	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675	NA	58858	3452	rs16998073-A	rs16998073	0	16998073	intergenic_variant	TRUE	NA	2e-17	16.69897000433602	(EA)	0.364	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	6q25.1	6	150683634	PLEKHG1	PLEKHG1	NA	NA	ENSG00000120278	NA	NA	rs17080102-G	rs17080102	0	17080102	5_prime_UTR_variant	FALSE	NA	3e-7	6.522878745280337	(EA)	0.394	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	6q25.1	6	150683634	PLEKHG1	PLEKHG1	NA	NA	ENSG00000120278	NA	NA	rs17080102-G	rs17080102	0	17080102	5_prime_UTR_variant	FALSE	NA	1e-6	6	NA	0.331	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p36.22	1	11802721	MTHFR	MTHFR	NA	NA	ENSG00000177000	NA	NA	rs17367504-A	rs17367504	0	17367504	intron_variant	FALSE	NA	2e-6	5.698970004336019	(EA)	0.253	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	1p36.22	1	11802721	MTHFR	MTHFR	NA	NA	ENSG00000177000	NA	NA	rs17367504-A	rs17367504	0	17367504	intron_variant	FALSE	NA	7e-6	5.154901959985743	NA	0.218	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7p15.2	7	27298248	EVX1, HIBADH	RPL35P4 - HNRNPA1P73	ENSG00000213783	ENSG00000236569	NA	28570	30359	rs17428471-G	rs17428471	0	17428471	intergenic_variant	TRUE	NA	3e-6	5.522878745280337	(EA)	0.326	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	7p15.2	7	27298248	EVX1, HIBADH	RPL35P4 - HNRNPA1P73	ENSG00000213783	ENSG00000236569	NA	28570	30359	rs17428471-G	rs17428471	0	17428471	intergenic_variant	TRUE	NA	9e-6	5.045757490560675	NA	0.286	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q24.13	12	112153882	NR	TRAFD1 - HECTD4	ENSG00000135148	ENSG00000173064	NA	278	6306	rs17630235-G	rs17630235	0	17630235	intergenic_variant	TRUE	NA	3e-15	14.522878745280337	NA	0.292	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q24.13	12	112153882	NR	TRAFD1 - HECTD4	ENSG00000135148	ENSG00000173064	NA	278	6306	rs17630235-G	rs17630235	0	17630235	intergenic_variant	TRUE	NA	3e-12	11.522878745280337	(EA)	0.271	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q24.13	12	112153882	NR	TRAFD1 - HECTD4	ENSG00000135148	ENSG00000173064	NA	278	6306	rs17630235-G	rs17630235	0	17630235	intergenic_variant	TRUE	NA	6e-6	5.221848749616356	(Latino)	0.613	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	6p22.2	6	26090951	HFE	HFE	NA	NA	ENSG00000010704	NA	NA	rs1799945-C	rs1799945	0	1799945	missense_variant	FALSE	NA	5e-6	5.301029995663981	(EA)	0.248	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	15q25.2	15	83130880	TM6SF1	HDGFL3, TM6SF1	NA	NA	ENSG00000166503, ENSG00000136404	NA	NA	rs2034618-C	rs2034618	0	2034618	3_prime_UTR_variant	FALSE	NA	5e-6	5.301029995663981	NA	0.192	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	8q24.12	8	119423572	NOV	CCN3	NA	NA	ENSG00000136999	NA	NA	rs2071518-C	rs2071518	0	2071518	3_prime_UTR_variant	FALSE	NA	3e-7	6.522878745280337	(EA)	0.223	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	8q24.12	8	119423572	NOV	CCN3	NA	NA	ENSG00000136999	NA	NA	rs2071518-C	rs2071518	0	2071518	3_prime_UTR_variant	FALSE	NA	4e-7	6.3979400086720375	NA	0.203	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10q11.21	10	44777631	CXCL12, TMEM72	NA - TMEM72-AS1	NA	ENSG00000224812	NA	NA	15488	rs2246438-G	rs2246438	0	2246438	intergenic_variant	TRUE	NA	5e-8	7.301029995663981	NA	0.22	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	10q11.21	10	44777631	CXCL12, TMEM72	NA - TMEM72-AS1	NA	ENSG00000224812	NA	NA	15488	rs2246438-G	rs2246438	0	2246438	intergenic_variant	TRUE	NA	4e-7	6.3979400086720375	(EA)	0.22	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q13.3	5	75742893	POC5, SV2C	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078	NA	25445	9677	rs258494-C	rs258494	0	258494	intergenic_variant	TRUE	NA	1e-9	9	NA	0.225	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	5q13.3	5	75742893	POC5, SV2C	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078	NA	25445	9677	rs258494-C	rs258494	0	258494	intergenic_variant	TRUE	NA	2e-7	6.698970004336019	(EA)	0.212	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	3p24.1	3	27521497	NR	RNU1-96P - Y_RNA	ENSG00000201033	ENSG00000199964	NA	7465	26260	rs2643826-C	rs2643826	0	2643826	regulatory_region_variant	TRUE	NA	2e-6	5.698970004336019	NA	0.171	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q21.33	12	89619312	ATP2B1	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs2681492-T	rs2681492	0	2681492	intron_variant	FALSE	NA	7e-8	7.154901959985743	NA	0.247	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q21.33	12	89619312	ATP2B1	ATP2B1	NA	NA	ENSG00000070961	NA	NA	rs2681492-T	rs2681492	0	2681492	intron_variant	FALSE	NA	2e-6	5.698970004336019	(EA)	0.241	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q24.3	2	164097664	NR	FIGN - PRPS1P1	ENSG00000182263	ENSG00000226847	NA	361652	115875	rs268263-T	rs268263	0	268263	intron_variant	TRUE	NA	7e-9	8.154901959985743	NA	0.232	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q24.3	2	164097664	NR	FIGN - PRPS1P1	ENSG00000182263	ENSG00000226847	NA	361652	115875	rs268263-T	rs268263	0	268263	intron_variant	TRUE	NA	4e-8	7.3979400086720375	(EA)	0.244	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	15q25.1	15	80723886	FAM108C1	ABHD17C	NA	NA	ENSG00000136379	NA	NA	rs2759308-G	rs2759308	0	2759308	intron_variant	FALSE	NA	5e-6	5.301029995663981	(EA)	0.178	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	17q21.33	17	49377145	NR	ZNF652 - PHB	ENSG00000198740	ENSG00000167085	NA	14672	26907	rs28406364-C	rs28406364	0	28406364	intron_variant	TRUE	NA	6e-14	13.221848749616356	NA	0.274	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	16q22.2	16	72074194	HPR	HPR, TXNL4B	NA	NA	ENSG00000261701, ENSG00000140830	NA	NA	rs2000999-A	rs2000999	0	2000999	intron_variant	FALSE	0.185	5e-45	44.30102999566398	(Trans-ethnic initial)	0.065	[0.056-0.074] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.185	NA	0.065
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	1p32.3	1	55038977	PCSK9	BSND - PCSK9	ENSG00000162399	ENSG00000169174	NA	21805	470	rs2479409-A	rs2479409	0	2479409	intergenic_variant	TRUE	0.667	3e-42	41.52287874528034	(Trans-ethnic initial)	0.0642	[0.056-0.072] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.667	NA	0.0642
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	20q12	20	41095698	MAFB	TOP1	NA	NA	ENSG00000198900	NA	NA	rs6065311-T	rs6065311	0	6065311	non_coding_transcript_exon_variant	FALSE	0.54	2e-34	33.69897000433602	(Trans-ethnic initial)	0.0417	[0.035-0.049] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.54	NA	0.0417
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	20q12	20	41095698	TOP1	TOP1	NA	NA	ENSG00000198900	NA	NA	rs6065311-T	rs6065311	0	6065311	non_coding_transcript_exon_variant	FALSE	0.54	2e-34	33.69897000433602	(Trans-ethnic initial)	0.0417	[0.035-0.049] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.54	NA	0.0417
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	16q13	16	56955678	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237	NA	10814	6245	rs247616-T	rs247616	0	247616	intergenic_variant	TRUE	0.293	1e-33	33	(Trans-ethnic initial)	0.0547	[0.047-0.063] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.293	NA	0.0547
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	5q33.3	5	156963286	TIMD4	TIMD4 - HAVCR1	ENSG00000145850	ENSG00000113249	NA	60	66127	rs6882076-T	rs6882076	0	6882076	regulatory_region_variant	TRUE	0.334	1e-33	33	(Trans-ethnic initial)	0.0456	[0.038-0.053] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.334	NA	0.0456
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	1p31.3	1	62628536	ANGPTL3	DOCK7	NA	NA	ENSG00000116641	NA	NA	rs11485618-A	rs11485618	0	11485618	3_prime_UTR_variant	FALSE	0.691	1e-31	31	(Trans-ethnic initial)	0.05	[0.042-0.058] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.691	NA	0.05
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	1p13.3	1	109279544	SORT1	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222	NA	3793	12	rs599839-A	rs599839	0	599839	intergenic_variant	TRUE	0.931	2e-31	30.69897000433602	(Asian initial, BMI unadjusted)	0.187	[0.16-0.22] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.931	NA	0.187
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	1q42.3	1	234713592	IRF2BP2	LINC00184 - LINC01132	ENSG00000224939	ENSG00000227630	NA	78812	10450	rs2587534-A	rs2587534	0	2587534	intron_variant	TRUE	0.528	2e-23	22.69897000433602	(Trans-ethnic initial)	0.0391	[0.032-0.046] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.528	NA	0.0391
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	8p23.1	8	9325848	PPP1R3B	RNU6-1151P - RNU6-526P	ENSG00000284864	ENSG00000201815	NA	38270	45242	rs9987289-A	rs9987289	0	9987289	non_coding_transcript_exon_variant	TRUE	0.0752	1e-22	22	(Trans-ethnic initial)	0.0714	[0.058-0.084] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.0752	NA	0.0714
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	11q24.2	11	126348646	ST3GAL4	GSEC, DCPS	NA	NA	ENSG00000280832, ENSG00000110063	NA	NA	rs17135399-A	rs17135399	0	17135399	3_prime_UTR_variant	FALSE	0.934	2e-22	21.69897000433602	(Trans-ethnic initial)	0.0797	[0.063-0.096] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.934	NA	0.0797
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	12q24.31	12	120978847	HNF1A	HNF1A-AS1, HNF1A	NA	NA	ENSG00000241388, ENSG00000135100	NA	NA	rs1169288-A	rs1169288	0	1169288	missense_variant	FALSE	0.666	2e-22	21.69897000433602	(Trans-ethnic initial)	0.0375	[0.03-0.045] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.666	NA	0.0375
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	5q13.3	5	75360714	HMGCR	HMGCR, CERT1	NA	NA	ENSG00000113161, ENSG00000113163	NA	NA	rs12916-T	rs12916	0	12916	3_prime_UTR_variant	FALSE	0.475	1e-21	21	(Asian initial, BMI unadjusted)	0.0773	[0.061-0.093] unit decrease	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.475	NA	0.0773
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	1q41	1	220796686	MOSC1	MTARC1	NA	NA	ENSG00000186205	NA	NA	rs2642438-A	rs2642438	0	2642438	missense_variant	FALSE	0.255	1e-19	19	(Trans-ethnic initial)	0.0352	[0.027-0.043] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.255	NA	0.0352
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	8q12.1	8	58440975	CYP7A1	UBXN2B	NA	NA	ENSG00000215114	NA	NA	rs13277801-T	rs13277801	0	13277801	intron_variant	FALSE	0.653	4e-19	18.397940008672037	(Trans-ethnic initial)	0.0338	[0.026-0.041] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.653	NA	0.0338
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	1p36.11	1	25434429	LDLRAP1	MACO1	NA	NA	ENSG00000204178	NA	NA	rs11802413-T	rs11802413	0	11802413	intron_variant	FALSE	0.537	2e-18	17.69897000433602	(Trans-ethnic initial)	0.0323	[0.025-0.039] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.537	NA	0.0323
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	11q23.3	11	116778201	APOA4, APOA5, APOA1, APOC3	ZPR1	NA	NA	ENSG00000109917	NA	NA	rs964184-C	rs964184	0	964184	3_prime_UTR_variant	FALSE	0.0	3e-18	17.522878745280337	(Trans-ethnic initial)	0.0855	[0.07-0.101] unit decrease (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0	NA	0.0855
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	8q24.3	8	143948489	PLEC1	PLEC	NA	NA	ENSG00000178209	NA	NA	rs7832643-T	rs7832643	0	7832643	intron_variant	FALSE	0.405	2e-17	16.69897000433602	(Trans-ethnic initial)	0.0339	[0.026-0.041] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.405	NA	0.0339
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	6p21.32	6	32444658	HLA	HLA-DRA, HLA-DRA, HLA-DRA, HLA-DRA, HLA-DRA, HLA-DRA, HLA-DRA	NA	NA	ENSG00000228987, ENSG00000206308, ENSG00000230726, ENSG00000204287, ENSG00000226260, ENSG00000227993, ENSG00000234794	NA	NA	rs3177928-A	rs3177928	0	3177928	3_prime_UTR_variant	FALSE	0.181	5e-17	16.30102999566398	(Trans-ethnic initial)	0.0452	[0.035-0.055] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.181	NA	0.0452
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	6p22.3	6	16108932	MYLIP	MDH1P2 - MYLIP	ENSG00000217585	ENSG00000007944	NA	339	20154	rs2294261-A	rs2294261	0	2294261	regulatory_region_variant	TRUE	0.487	8e-17	16.096910013008056	(Trans-ethnic initial)	0.0333	[0.026-0.041] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.487	NA	0.0333
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	10q25.2	10	112150963	GPAM	GPAM	NA	NA	ENSG00000119927	NA	NA	rs1129555-A	rs1129555	0	1129555	3_prime_UTR_variant	FALSE	0.323	1e-15	15	(Trans-ethnic initial)	0.0303	[0.022-0.038] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.323	NA	0.0303
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	19p13.2	19	11131631	LDLR	SPC24, LDLR	NA	NA	ENSG00000161888, ENSG00000130164	NA	NA	rs2738464-C	rs2738464	0	2738464	3_prime_UTR_variant	FALSE	0.73	3e-15	14.522878745280337	(Asian initial, BMI unadjusted)	0.095	[0.071-0.119] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.73	NA	0.095
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	16q22.2	16	71981352	PKD1L3	PKD1L3	NA	NA	ENSG00000277481	NA	NA	rs8051431-C	rs8051431	0	8051431	intron_variant	FALSE	0.71	4e-15	14.397940008672037	(Asian initial, BMI unadjusted)	0.075	[0.057-0.093] unit increase	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.71	NA	0.075
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	7p13	7	44539581	NPC1L1	NPC1L1	NA	NA	ENSG00000015520	NA	NA	rs2072183-C	rs2072183	0	2072183	synonymous_variant	FALSE	0.237	2e-14	13.698970004336019	(Trans-ethnic initial)	0.0386	[0.029-0.048] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.237	NA	0.0386
2017-06-26	28334899	Spracklen CN	2017-02-21	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	LDL cholesterol levels	32,285 East Asian ancestry individuals, 173,082 European ancestry individuals	8,478 Chinese ancestry individuals	14q12	14	24414681	NYNRIN	NYNRIN	NA	NA	ENSG00000205978	NA	NA	rs8017377-A	rs8017377	0	8017377	missense_variant	FALSE	0.459	2e-14	13.698970004336019	(Trans-ethnic initial)	0.0303	[0.023-0.038] unit increase (EA Beta value)	Affymetrix, Illumina [~ 1900000] (imputed)	N	low density lipoprotein cholesterol measurement	http://www.ebi.ac.uk/efo/EFO_0004611	GCST004233	Genome-wide genotyping array	0.459	NA	0.0303
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	15q15.1	15	42359702	CAPN3	CAPN3	NA	NA	ENSG00000092529	NA	NA	rs149698681-C	rs149698681	0	149698681	5_prime_UTR_variant	FALSE	0.0219	8e-13	12.096910013008056	NA	0.08823505	[0.064-0.112] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0219	NA	0.08823505
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	15q15.3	15	43735687	CATSPER2P1	CATSPER2P1	NA	NA	ENSG00000205771	NA	NA	rs139974673-C	rs139974673	0	139974673	intron_variant	FALSE	0.026	4e-10	9.397940008672037	NA	0.07087201	[0.049-0.093] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.026	NA	0.07087201
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	15q22.31	15	64194343	CSNK1G1, CTD-2116N17.1	CSNK1G1	NA	NA	ENSG00000169118	NA	NA	rs539389645-CT	rs539389645	1	144287899	intron_variant	FALSE	0.1205	2e-11	10.698970004336019	NA	0.03700482	[0.026-0.048] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1205	NA	0.03700482
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	15q22.31	15	65450052	DPP8	DPP8	NA	NA	ENSG00000074603	NA	NA	rs28574727-T	rs28574727	0	28574727	intron_variant	FALSE	0.1841	1e-15	15	NA	0.0367303	[0.028-0.046] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1841	NA	0.0367303
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	NA	NA	NA	SCAMP2	NA	NA	NA	NA	NA	NA	chr15:75139426-G	chr15:75139426	0	NA	NA	TRUE	0.5821	5e-11	10.301029995663981	NA	0.02376081	[0.017-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.5821	NA	0.02376081
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	15q25.1	15	79930230	intergenic	ST20-AS1 - BCL2A1	ENSG00000259642	ENSG00000140379	NA	3237	30662	rs12916091-G	rs12916091	0	12916091	regulatory_region_variant	TRUE	0.563	2e-27	26.69897000433602	NA	0.03899083	[0.032-0.046] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.563	NA	0.03899083
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	15q25.1	15	79967933	BCL2A1	BCL2A1	NA	NA	ENSG00000140379	NA	NA	rs76648483-T	rs76648483	0	76648483	intron_variant	FALSE	0.2568	6e-97	96.22184874961636	NA	0.08518855	[0.077-0.093] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2568	NA	0.08518855
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	NA	NA	NA	AKAP13	NA	NA	NA	NA	NA	NA	chr15:86122779-C	chr15:86122779	0	NA	NA	TRUE	0.6741	7e-10	9.154901959985743	NA	0.02343536	[0.016-0.031] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.6741	NA	0.02343536
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	15q26.3	15	101176592	CHSY1	CHSY1	NA	NA	ENSG00000131873	NA	NA	rs3784526-A	rs3784526	0	3784526	3_prime_UTR_variant	FALSE	0.1078	9e-13	12.045757490560675	NA	0.04125107	[0.03-0.053] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.10780000000000001	NA	0.04125107
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q12.2	16	53206360	CHD9	CHD9	NA	NA	ENSG00000177200	NA	NA	rs770414535-G	rs770414535	1	77414875	intron_variant	FALSE	0.2573	3e-11	10.522878745280337	NA	0.02827739	[0.02-0.037] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2573	NA	0.02827739
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q23.1	16	74567588	GLG1	GLG1	NA	NA	ENSG00000090863	NA	NA	rs12924604-A	rs12924604	0	12924604	intron_variant	FALSE	0.1979	6e-14	13.221848749616356	NA	0.03349513	[0.025-0.042] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1979	NA	0.03349513
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85893115	intergenic	COX4I1 - IRF8	ENSG00000131143	ENSG00000140968	NA	86047	6047	rs395498-G	rs395498	0	395498	intergenic_variant	TRUE	0.3488	6e-116	115.22184874961636	NA	0.08593058	[0.079-0.093] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3488	NA	0.08593058
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85899046	IRF8	COX4I1 - IRF8	ENSG00000131143	ENSG00000140968	NA	91978	116	rs56177354-T	rs56177354	0	56177354	regulatory_region_variant	TRUE	0.0623	2e-111	110.69897000433602	NA	0.1730887	[0.16-0.19] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0623	NA	0.1730887
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85900910	IRF8	IRF8	NA	NA	ENSG00000140968	NA	NA	rs34993178-AT	rs34993178	0	34993178	intron_variant	FALSE	0.0633	7e-102	101.15490195998575	NA	0.1589751	[0.14-0.17] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0633	NA	0.1589751
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	NA	NA	NA	IRF8	NA	NA	NA	NA	NA	NA	chr16:85935797-C	chr16:85935797	0	NA	NA	TRUE	0.1711	2e-136	135.69897000433602	NA	0.1183281	[0.11-0.13] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1711	NA	0.1183281
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85902784	IRF8	IRF8	NA	NA	ENSG00000140968	NA	NA	rs113899791-TGGTGGCTGCA	rs113899791	1	29001489	5_prime_UTR_variant	FALSE	0.433	3e-226	225.52287874528034	NA	0.1179164	[0.11-0.13] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.433	NA	0.1179164
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85911217	IRF8	IRF8	NA	NA	ENSG00000140968	NA	NA	rs2292982-G	rs2292982	0	2292982	intron_variant	FALSE	0.3385	9e-81	80.04575749056067	NA	0.07181204	[0.064-0.079] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.3385	NA	0.07181204
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85913869	IRF8	IRF8	NA	NA	ENSG00000140968	NA	NA	rs8064111-T	rs8064111	0	8064111	intron_variant	FALSE	0.1294	5e-153	152.30102999566398	NA	0.1409652	[0.13-0.15] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1294	NA	0.1409652
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85939534	RP11-542M13.3	LINC02132 - NA	ENSG00000268804	NA	NA	3311	NA	rs11641153-G	rs11641153	0	11641153	intron_variant	TRUE	0.2282	8e-93	92.09691001300806	NA	0.08750669	[0.079-0.096] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2282	NA	0.08750669
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85957794	intergenic	LINC02132 - NA	ENSG00000268804	NA	NA	21571	NA	rs75479997-T	rs75479997	0	75479997	intergenic_variant	TRUE	0.1124	2e-22	21.69897000433602	NA	0.05485719	[0.044-0.066] unit decrease	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.1124	NA	0.05485719
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85959528	intergenic	LINC02132 - NA	ENSG00000268804	NA	NA	23305	NA	rs2361763-T	rs2361763	0	2361763	intergenic_variant	TRUE	0.4749	4e-67	66.39794000867204	NA	0.06251537	[0.055-0.07] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.4749	NA	0.06251537
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85961830	intergenic	LINC02132 - LINC01082	ENSG00000268804	ENSG00000269186	NA	25607	234124	rs113646461-C	rs113646461	0	113646461	intergenic_variant	TRUE	0.0767	3e-97	96.52287874528034	NA	0.139778	[0.13-0.15] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.0767	NA	0.139778
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	16q24.1	16	85982722	RP11-542M13.2	LINC02132 - LINC01082	ENSG00000268804	ENSG00000269186	NA	46499	213232	rs11642657-T	rs11642657	0	11642657	intron_variant	TRUE	0.009	2e-24	23.69897000433602	NA	0.2097587	[0.17-0.25] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.009	NA	0.2097587
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17p13.1	17	7330793	AC026954.6	NEURL4 - ACAP1	ENSG00000215041	ENSG00000072818	NA	1400	5736	rs3809822-G	rs3809822	0	3809822	non_coding_transcript_exon_variant	TRUE	0.2438	2e-10	9.698970004336019	NA	0.0264869	[0.018-0.035] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.2438	NA	0.0264869
2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Monocyte percentage of white cells	170,494 European ancestry individuals	NA	17p13.1	17	7839283	KDM6B	KDM6B	NA	NA	ENSG00000132510	NA	NA	rs74480102-A	rs74480102	0	74480102	intron_variant	FALSE	0.043	8e-16	15.096910013008056	NA	0.07074734	[0.054-0.088] unit increase	Affymetrix [~ 2500000] (imputed)	N	monocyte percentage of leukocytes	http://www.ebi.ac.uk/efo/EFO_0007989	GCST004609	Genome-wide genotyping array	0.043	NA	0.07074734
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	17p13.1	17	9044391	NTN1	NTN1	NA	NA	ENSG00000065320	NA	NA	rs12944377-?	rs12944377	0	12944377	intron_variant	FALSE	NR	8e-10	9.096910013008056	(EA)	1.4084507	NA	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.4084507	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	1p22.1	1	94109752	ARHGAP29	ABCA4	NA	NA	ENSG00000198691	NA	NA	rs3789432-?	rs3789432	0	3789432	intron_variant	FALSE	NR	1e-8	8	(Asian)	1.4084507	NA	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.4084507	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	1q32.2	1	209818782	IRF6	IRF6 - UTP25	ENSG00000117595	ENSG00000117597	NA	12607	9190	rs12070337-?	rs12070337	0	12070337	intergenic_variant	TRUE	NR	6e-12	11.221848749616356	(Asian)	1.4705882	NA	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.4705882	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	9q33.3	9	124748390	Intergenic	NR6A1	NA	NA	ENSG00000148200	NA	NA	rs78427461-?	rs78427461	0	78427461	intron_variant	FALSE	NR	8e-6	5.096910013008056	(Asian)	1.41	[1.23-1.62]	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.41	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	10q25.3	10	117057556	VAX1	SHTN1	NA	NA	ENSG00000187164	NA	NA	rs1898349-?	rs1898349	0	1898349	intron_variant	FALSE	NR	1e-7	7	(Asian)	1.35	[1.21-1.49]	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.35	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	20q12	20	40656135	MAFB	NA - MAFB	NA	ENSG00000204103	NA	NA	29713	rs6029258-?	rs6029258	0	6029258	intergenic_variant	TRUE	NR	6e-12	11.221848749616356	(Asian)	1.4705882	NA	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.4705882	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	8q24.21	8	128963890	Intergenic	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs55658222-?	rs55658222	0	55658222	intron_variant	FALSE	NR	8e-44	43.096910013008056	NA	2.13	[1.78-2.54] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	2.13	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	1q32.2	1	209811125	IRF6	IRF6 - UTP25	ENSG00000117595	ENSG00000117597	NA	4950	16847	rs75477785-?	rs75477785	0	75477785	intergenic_variant	TRUE	NR	4e-29	28.397940008672037	NA	1.754386	[1.54-2.04] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.754386	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	17p13.1	17	9044391	NTN1	NTN1	NA	NA	ENSG00000065320	NA	NA	rs12944377-?	rs12944377	0	12944377	intron_variant	FALSE	NR	8e-21	20.096910013008056	NA	1.5151515	[1.35-1.72] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.5151515	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	1p22.1	1	94092554	ARHGAP29	ABCA4	NA	NA	ENSG00000198691	NA	NA	rs66515264-?	rs66515264	0	66515264	intron_variant	FALSE	NR	4e-17	16.397940008672037	NA	1.506	[1.31-1.73] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.506	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	1p36.13	1	18646282	PAX7	PAX7	NA	NA	ENSG00000009709	NA	NA	rs9439713-?	rs9439713	0	9439713	intron_variant	FALSE	NR	6e-13	12.221848749616356	NA	1.481	[1.27-1.73] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.481	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	20q12	20	40632414	MAFB	NA - MAFB	NA	ENSG00000204103	NA	NA	53434	rs6072081-?	rs6072081	0	6072081	regulatory_region_variant	TRUE	NR	2e-12	11.698970004336019	NA	1.4285715	[1.28-1.59] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.4285715	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	8q21.3	8	87856112	DCAF4L2	SOX5P1 - DCAF4L2	ENSG00000254376	ENSG00000176566	NA	66424	14635	rs12543318-?	rs12543318	0	12543318	intergenic_variant	TRUE	NR	9e-12	11.045757490560675	NA	1.3	[1.17-1.45] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.3	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	10q25.3	10	117086783	VAX1	SHTN1	NA	NA	ENSG00000187164	NA	NA	rs10886040-?	rs10886040	0	10886040	intron_variant	FALSE	NR	9e-11	10.045757490560675	NA	1.31	[1.17-1.46] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.31	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	13q31.1	13	80105167	SPRY2	LINC01080 - NA	ENSG00000281721	NA	NA	76884	NA	rs11841646-?	rs11841646	0	11841646	intergenic_variant	TRUE	NR	4e-10	9.397940008672037	NA	1.33	[1.17-1.50] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.33	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	17q22	17	56695877	NOG	NA - C17orf67	NA	ENSG00000214226	NA	NA	96036	rs227731-?	rs227731	0	227731	intergenic_variant	TRUE	NR	2e-9	8.698970004336019	NA	1.24	[1.12-1.38] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.24	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	2p24.2	2	16548089	FAM49A	NA - CYRIA	NA	ENSG00000197872	NA	NA	1370	rs7566780-?	rs7566780	0	7566780	intron_variant	TRUE	NR	4e-9	8.397940008672037	NA	1.2	[1.08-1.34] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.2	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	3q28	3	189835583	TP63	TP63	NA	NA	ENSG00000073282	NA	NA	rs76479869-?	rs76479869	0	76479869	intron_variant	FALSE	NR	1e-8	8	NA	1.79	[1.41-2.29] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.79	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	15q24.1	15	74596822	ARID3B	ARID3B	NA	NA	ENSG00000179361	NA	NA	rs11072494-?	rs11072494	0	11072494	3_prime_UTR_variant	FALSE	NR	2e-8	7.698970004336019	NA	1.1904762	[1.05-1.33] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.1904762	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	3q12.1	3	99972678	COL8A1	FILIP1L, CMSS1	NA	NA	ENSG00000168386, ENSG00000184220	NA	NA	rs68092024-?	rs68092024	0	68092024	intron_variant	FALSE	NR	5e-8	7.301029995663981	NA	1.3513513	[1.19-1.52] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.3513513	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	4q21.1	4	76628406	SHROOM3	SHROOM3	NA	NA	ENSG00000138771	NA	NA	rs6838801-?	rs6838801	0	6838801	intron_variant	FALSE	NR	6e-8	7.221848749616356	NA	1.24	[1.11-1.38] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.24	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	12q13.13	12	52963551	KRT18	KRT18 - EIF4B	ENSG00000111057	ENSG00000063046	NA	10645	42731	rs2363632-?	rs2363632	0	2363632	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	NA	1.369863	[1.19-1.56] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.369863	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	5q13.1	5	68187904	PIK3R1	EEF1B2P2 - LINC02219	ENSG00000213864	ENSG00000253787	NA	28011	1972	rs6449957-?	rs6449957	0	6449957	intergenic_variant	TRUE	NR	2e-7	6.698970004336019	NA	1.1764705	[1.05-1.32] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.1764705	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	8p12	8	32476054	NRG1	NRG1	NA	NA	ENSG00000157168	NA	NA	rs1878918-?	rs1878918	0	1878918	intron_variant	FALSE	NR	3e-7	6.522878745280337	NA	1.29	[1.15-1.45] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.29	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft lip with or without cleft palate	83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios.	NA	17q21.32	17	46928337	GOSR2, WNT9B	GOSR2	NA	NA	ENSG00000108433	NA	NA	rs3785888-?	rs3785888	0	3785888	intron_variant	FALSE	NR	4e-7	6.3979400086720375	NA	1.14	[1.03-1.27] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Cleft palate, cleft lip	http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959	GCST004050	Genome-wide genotyping array	NA	1.14	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft palate	272 Asian ancestry case-parent trios, 161 Asian ancestry controls, 38 European ancestry cases, 296 European ancestry case-parent trios, 835 European ancestry controls, 40 Latino or African cases, 34 Latino or African case-parent trios, 704 Latino or African controls, 14 case-parent trios.	NA	8q24.3	8	140502973	NR	TRAPPC9 - CHRAC1	ENSG00000167632	ENSG00000104472	NA	44394	8338	rs4246129-?	rs4246129	0	4246129	intergenic_variant	TRUE	NR	5e-6	5.301029995663981	(Asian)	2	[1.47-2.63]	Illumina [6090031] (imputed)	N	Cleft palate	http://purl.obolibrary.org/obo/HP_0000175	GCST004052	Genome-wide genotyping array	NA	2	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Cleft palate	272 Asian ancestry case-parent trios, 161 Asian ancestry controls, 38 European ancestry cases, 296 European ancestry case-parent trios, 835 European ancestry controls, 40 Latino or African cases, 34 Latino or African case-parent trios, 704 Latino or African controls, 14 case-parent trios.	NA	16p12.1	16	25190659	LCMT1	RN7SL557P - AQP8	ENSG00000266166	ENSG00000103375	NA	5121	25072	rs57933945-?	rs57933945	0	57933945	intergenic_variant	TRUE	NR	3e-6	5.522878745280337	(Asian)	2.857143	[1.85-4.35]	Illumina [6090031] (imputed)	N	Cleft palate	http://purl.obolibrary.org/obo/HP_0000175	GCST004052	Genome-wide genotyping array	NA	2.857143	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	1q32.2	1	209819156	IRF6	IRF6 - UTP25	ENSG00000117595	ENSG00000117597	NA	12981	8816	rs1109430-?	rs1109430	0	1109430	intergenic_variant	TRUE	NR	1e-21	21	NA	1.82	[1.55-2.12] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.82	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	8q24.21	8	128952627	Intergenic	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs17242358-?	rs17242358	0	17242358	intron_variant	FALSE	NR	6e-37	36.221848749616356	NA	1.4925373	[1.32-1.69] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.4925373	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	17p13.1	17	9044391	NTN1	NTN1	NA	NA	ENSG00000065320	NA	NA	rs12944377-?	rs12944377	0	12944377	intron_variant	FALSE	NR	1e-16	16	NA	1.3513513	[1.22-1.49] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.3513513	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	1p22.1	1	94092554	ARHGAP29	ABCA4	NA	NA	ENSG00000198691	NA	NA	rs66515264-?	rs66515264	0	66515264	intron_variant	FALSE	NR	6e-15	14.221848749616356	NA	1.4	[1.24-1.59] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.4	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	20q12	20	40632414	MAFB	NA - MAFB	NA	ENSG00000204103	NA	NA	53434	rs6072081-?	rs6072081	0	6072081	regulatory_region_variant	TRUE	NR	9e-13	12.045757490560675	NA	1.3513513	[1.23-1.47] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.3513513	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	8q21.3	8	87856112	DCAF4L2	SOX5P1 - DCAF4L2	ENSG00000254376	ENSG00000176566	NA	66424	14635	rs12543318-?	rs12543318	0	12543318	intergenic_variant	TRUE	NR	8e-11	10.096910013008056	NA	1.26	[1.15-1.38] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.26	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	10q25.3	10	117086783	VAX1	SHTN1	NA	NA	ENSG00000187164	NA	NA	rs10886040-?	rs10886040	0	10886040	intron_variant	FALSE	NR	8e-11	10.096910013008056	NA	1.26	[1.14-1.39] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.26	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	1p36.13	1	18646282	PAX7	PAX7	NA	NA	ENSG00000009709	NA	NA	rs9439713-?	rs9439713	0	9439713	intron_variant	FALSE	NR	4e-10	9.397940008672037	NA	1.3	[1.14-1.49] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.3	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	9q22.33	9	97857437	FOXE1	FOXE1 - TRMO	ENSG00000178919	ENSG00000136932	NA	720	47052	rs12347191-?	rs12347191	0	12347191	intergenic_variant	TRUE	NR	1e-9	9	NA	1.2820514	[1.14-1.45] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.2820514	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	2p24.2	2	16548089	FAM49A	NA - CYRIA	NA	ENSG00000197872	NA	NA	1370	rs7566780-?	rs7566780	0	7566780	intron_variant	TRUE	NR	1e-8	8	NA	1.18	[1.07-1.29] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.18	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	13q31.1	13	80105167	SPRY2	LINC01080 - NA	ENSG00000281721	NA	NA	76884	NA	rs11841646-?	rs11841646	0	11841646	intergenic_variant	TRUE	NR	3e-8	7.522878745280337	NA	1.19	[1.07-1.33] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.19	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	17q21.32	17	46942365	GOSR2, WNT9B	GOSR2	NA	NA	ENSG00000108433	NA	NA	rs6504622-?	rs6504622	0	6504622	intron_variant	FALSE	NR	1e-7	7	NA	1.1627907	[1.06-1.28] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.1627907	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	8p12	8	32523319	NRG1	NRG1	NA	NA	ENSG00000157168	NA	NA	rs10088648-?	rs10088648	0	10088648	intron_variant	FALSE	NR	1e-7	7	NA	1.2195122	[1.1-1.35] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.2195122	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	3q28	3	189835583	TP63	TP63	NA	NA	ENSG00000073282	NA	NA	rs76479869-?	rs76479869	0	76479869	intron_variant	FALSE	NR	3e-7	6.522878745280337	NA	1.56	[1.27-1.93] (GENEVA cohort)	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.56	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	1p36.13	1	18649995	PAX7	PAX7	NA	NA	ENSG00000009709	NA	NA	rs9439714-?	rs9439714	0	9439714	intron_variant	FALSE	NR	5e-7	6.301029995663981	(EA)	1.33	[1.2-1.47]	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.33	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	6p24.3	6	10296103	intergenic	RNU6ATAC21P - TFAP2A	ENSG00000221583	ENSG00000137203	NA	73942	97083	rs1333657-?	rs1333657	0	1333657	intergenic_variant	TRUE	NR	8e-6	5.096910013008056	(EA)	1.29	[1.16-1.42]	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.29	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	8q21.3	8	87856112	intergenic	SOX5P1 - DCAF4L2	ENSG00000254376	ENSG00000176566	NA	66424	14635	rs12543318-?	rs12543318	0	12543318	intergenic_variant	TRUE	NR	1e-7	7	(EA)	1.34	[1.21-1.48]	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.34	NA
2017-05-19	28054174	Leslie EJ	2017-01-04	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28054174	Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.	Orofacial clefts	83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios.	NA	8q24.21	8	128921474	intergenic	CCDC26	NA	NA	ENSG00000229140	NA	NA	rs72728734-?	rs72728734	0	72728734	intron_variant	FALSE	NR	5e-20	19.30102999566398	(EA)	1.76	[1.56-1.98]	Illumina [6090031] (imputed)	N	Oral cleft	http://purl.obolibrary.org/obo/HP_0000202	GCST004051	Genome-wide genotyping array	NA	1.76	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	17q21.33	17	49377145	NR	ZNF652 - PHB	ENSG00000198740	ENSG00000167085	NA	14672	26907	rs28406364-C	rs28406364	0	28406364	intron_variant	TRUE	NA	3e-10	9.522878745280337	(EA)	0.249	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q24.12	12	111446804	SH2B3	SH2B3, ATXN2	NA	NA	ENSG00000111252, ENSG00000204842	NA	NA	rs3184504-T	rs3184504	0	3184504	missense_variant	FALSE	NA	6e-18	17.221848749616356	NA	0.316	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q24.12	12	111446804	SH2B3	SH2B3, ATXN2	NA	NA	ENSG00000111252, ENSG00000204842	NA	NA	rs3184504-T	rs3184504	0	3184504	missense_variant	FALSE	NA	9e-15	14.045757490560675	(EA)	0.299	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	12q24.12	12	111446804	SH2B3	SH2B3, ATXN2	NA	NA	ENSG00000111252, ENSG00000204842	NA	NA	rs3184504-T	rs3184504	0	3184504	missense_variant	FALSE	NA	4e-6	5.3979400086720375	(Latino)	0.609	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	22q12.1	22	28755162	HSCB	HSCB	NA	NA	ENSG00000100209	NA	NA	rs34887403-G	rs34887403	0	34887403	intron_variant	FALSE	NA	1e-6	6	(EA)	0.268	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	22q12.1	22	28755162	HSCB	HSCB	NA	NA	ENSG00000100209	NA	NA	rs34887403-G	rs34887403	0	34887403	intron_variant	FALSE	NA	4e-6	5.3979400086720375	NA	0.233	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	6q16.1	6	96437529	FUT9, UFL1	UFL1-AS1	NA	NA	ENSG00000233797	NA	NA	rs35410524-C	rs35410524	0	35410524	intron_variant	FALSE	NA	9e-6	5.045757490560675	(EA)	0.217	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	6q16.1	6	96437529	FUT9, UFL1	UFL1-AS1	NA	NA	ENSG00000233797	NA	NA	rs35410524-C	rs35410524	0	35410524	intron_variant	FALSE	NA	1e-6	6	NA	0.22	unit decrease	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	2q14.3	2	123263214	TSN, CNTNAP5	NA	NA	NA	NA	NA	NA	rs3923097-T	rs3923097	0	3923097	intergenic_variant	TRUE	NA	6e-6	5.221848749616356	NA	0.32	unit increase	Affymetrix [at least 2696785] (imputed)	N	diastolic blood pressure	http://www.ebi.ac.uk/efo/EFO_0006336	GCST007098	Genome-wide genotyping array	NA	NA	NA
2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Diastolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals	NA	4q31.21	4	144350